CN102202619B

CN102202619B - Reduced-pressure, wound-treatment dressings and systems

Info

Publication number: CN102202619B
Application number: CN200980143982.7A
Authority: CN
Inventors: 克里斯多佛·布赖恩·洛克; 蒂莫西·马克·罗宾逊
Original assignee: KCI Licensing Inc
Current assignee: 3M Innovative Properties Co
Priority date: 2008-11-07
Filing date: 2009-11-02
Publication date: 2014-03-12
Anticipated expiration: 2029-11-02
Also published as: CN102202619A; EP2361069A1; EP2361069B1; US20130253401A1; EP2361069A4; JP2015097792A; EP3421020B1; RU2011114000A; KR101644206B1; BRPI0916062A2; WO2010053870A1; KR20110083709A; AU2009311352A1; US8460257B2; JP5864711B2; US20190298577A1; MX2011004820A; JP2012508037A; EP3421020A1; AU2009311352B2

Abstract

A wound-closing dressing, which is suitable for use as part of a reduced-pressure, wound-treatment system, may include a sealing drape, one or more contracting elements, and a gripping member. The contracting element may be coupled to the sealing drape and is configured to contract when activated and to generate a closing force. A gripping member is coupled to the sealing drape and is configured to transmit the closing force to a patient's epidermis. Other dressings, systems, and methods are also disclosed.

Description

Reduced-pressure, wound-treatment dressings and system

Related application

The U.S. Provisional Patent Application serial number 61/112 that the exercise question that the present invention requires to submit on November 7th, 2008 according to 35U.S.C. § 119 (e) is " Reduced-Pressure Wound Treatment Dressing and System (reduced-pressure, wound-treatment dressings and system) ", 371 rights and interests, 61/112,371 is merged in herein by reference for all objects.

Technical field

The present invention relates generally to medical treatment system, and more particularly, relates to reduced-pressure, wound-treatment dressings, system and method.

Background technology

Wound can be by wittingly, surgical incision for example, or by mistake, for example, in accident, produced.In both cases, the closure of wound is for preventing that the loss of important body fluid and the intrusion of microorganism from being important.Wound is typically by being used suture or nail to be closed.

Yet the use of suture or nail may have less desirable side effect.For example, the insertion of suture or nail necessarily relates to patient is suffered for making suture or nail enter the extra wound of patient's epidermis.These extra wounds also stand possible infection.In addition, although wound self can cause cicatrix, from the extra wound of suture or nail, also can cause extra scar, what this may unnecessarily give prominence to initial wound scar is aesthetic less desirable essence.

Summary of the invention

The invention solves the shortcoming of Wound care, as shown in various illustrative nonrestrictive embodiment herein and describe.According to illustrative nonrestrictive embodiment, the reduced-pressure wound treatment systems that is used for the treatment of patient's wound with it comprises wound closure dressing, for being arranged in, seals the surface towards tissue of drop cloth and the manifold member between wound; And for transmit the decompression subsystem of decompression to wound closure dressing.Wound closure dressing comprise have first surface and towards tissue surperficial sealing drop cloth, be coupled in sealing drop cloth contraction elements and be coupled in sealing drop cloth clamping component (gripping member).Sealing drop cloth is used for being placed on wound.Contraction elements is configured to when being activated, shrink and produce thus closing force.Clamping component is configured to the epidermis to patient by closed force transfer.Sealing drop cloth and clamping component are configured to form fluid-tight in wound.

According to another illustrative nonrestrictive embodiment, wound closure dressing comprise have first surface and towards tissue surperficial sealing drop cloth, be coupled in sealing drop cloth contraction elements and be coupled in sealing drop cloth clamping component.Sealing drop cloth is used for being placed on wound.Contraction elements is configured to when being activated, shrink and produce thus closing force.Clamping component is configured to the epidermis to patient by closed force transfer.Sealing drop cloth and clamping component are configured to form fluid-tight in wound.

According to another illustrative nonrestrictive embodiment, wound closure dressing comprise there is first surface and towards the surperficial sealing drop cloth of tissue, be coupled in the sealing solvable disintegration of drop cloth and the elastic component that is coupled in solvable disintegration in stretch position.Sealing drop cloth is used for being placed on wound.Elastic component is contracted to free position when at least a portion of solvable disintegration is dissolved, and produces thus closing force.Wound closure dressing also comprises at least one the clamping component being coupled in sealing drop cloth and elastic component.Clamping component is configured to the epidermis to patient by closed force transfer.

According to another illustrative nonrestrictive embodiment, the method that is used for the treatment of wound comprises the following steps: the epidermis that contraction elements is fixed on to patient, make contraction elements cross at least a portion of patient's wound, and activate contraction elements, make contraction elements produce closing force.Thereby contraction elements is configured to from extended position, be contracted to punctured position and produce closing force when being activated.

According to another illustrative nonrestrictive embodiment, the method of manufacturing wound closure dressing comprises the following steps: form and have first surface and towards the surperficial sealing drop cloth of tissue, contraction elements is coupled in to sealing drop cloth, and clamping component is coupled in to sealing drop cloth.Clamping component is configured to the epidermis to patient by closed force transfer.Thereby contraction elements is configured to from extended position, be contracted to punctured position and produce closing force when being activated.

Accompanying drawing summary

When by reference to the accompanying drawings with reference to following detailed description in detail, can obtain and understand more completely of the present invention, in the accompanying drawings:

Fig. 1 is the schematic perspective view of illustrative nonrestrictive embodiment that is used for the treatment of the system of patient's wound with it;

Fig. 2 is the schematic viewgraph of cross-section that the line 2-2 along in Fig. 1 of the system of Fig. 1 gets;

Fig. 3 A is the schematic top view of the system of Fig. 1;

Fig. 3 B is the schematic top view of the system of Fig. 1, shows some and is activated and produces thus the contraction elements of closing force;

Fig. 4 A is the schematic top view of illustrative nonrestrictive embodiment that is shown as the wound closure dressing of wound coverage;

Fig. 4 B is the schematic top view of the dressing of Fig. 4 A, and showing is activated produces the contraction elements of closing force thus;

Fig. 5 is the schematic top view of illustrative nonrestrictive embodiment that is used for the treatment of the system of wound;

The schematic top view of the illustrative nonrestrictive embodiment of the system that be used for the treatment of wound of Fig. 6 shown in being;

Fig. 7 A is the schematic upward view of a part of illustrative nonrestrictive embodiment that is used for the treatment of the system of wound;

Fig. 7 B is the schematic perspective view of the system of Fig. 7 A;

Fig. 8 is the schematic perspective view of a part of illustrative nonrestrictive embodiment that is used for the treatment of the system of wound;

Fig. 9 A is the schematic top view of the components of system as directed of Fig. 8; And

Fig. 9 B is the schematic top view of the components of system as directed of Fig. 8, thereby shows some dissolved pearl that makes corresponding elastic component produce closing force.

Detailed Description Of The Invention

Following to the detailed description of preferred embodiment in, with reference to accompanying drawing, accompanying drawing forms a part for illustrative embodiment, and wherein shows as an example the specific embodiment that the present invention can be put into practice.These embodiments are enough described to enable those skilled in the art to put into practice in detail the present invention, and should be appreciated that can utilize other embodiment and can make logical structure, machinery, electricity and chemistry variation and do not depart from the spirit or scope of the present invention.For fear of to enabling those skilled in the art to put into practice the unnecessary details of the present invention, description may have been saved some information known to those skilled in the art.Therefore, the following detailed description should be at the meaning understanding of restriction, and scope of the present invention is only defined by the appended claims.

, mainly with reference to Fig. 1-3B, show the first illustrative nonrestrictive embodiment of the reduced-pressure wound treatment systems 100 that is used for the treatment of patient's wound 102 with it now.Reduced-pressure wound treatment systems 100 comprises wound closure dressing 110, manifold member 112 and decompression subsystem 114 substantially.Reduced-pressure wound treatment systems 100 is shown in the region of wound 102.In this diagram, wound 102 is through epidermis 104 (or skin), corium 106, and arrival hypodermis or subcutaneous tissue 108.Subcutaneous tissue 108 can comprise many organization types, for example fatty tissue or muscle.Although wound 102 is shown as through epidermis 104, corium 106 and arrives in subcutaneous tissue 108 in this illustrative embodiment, will recognize, reduced-pressure wound treatment systems 100 can be used for the treatment of the wound with any degree of depth.

Wound closure dressing 110 comprises sealing drop cloth 116, one or more contraction elements 118 and clamping component 120.Sealing drop cloth 116 comprise first surface 122 and towards tissue second surface 124.Sealing drop cloth 116 can be by controlling dimension, make to seal drop cloth 116 so that drop cloth extension (drape extension) 126 to extend beyond mode and the wound 102 of periphery of wound 102 overlapping.

Sealing drop cloth 116 can be the material of elastomer." elastomer " means to have elastomeric character.It typically refers to the polymeric material with the character as rubber.More specifically, most of elastomers have percentage elongation and the sizable resilience that is greater than 100%.The resilience of material refers to the ability that material recovers from elastic deformation.Elastomeric example can include but not limited to: natural rubber, polyisoprene, butadiene-styrene rubber, neoprene, polybutadiene, acrylonitrile-butadiene rubber, butyl rubber, EP rubbers, EPDM monomer, chlorosulfonated polyethylene, thiorubber., polyurethanes, EVA film, copolyesters and silicones.In addition, the concrete example of seal member material comprises silicones drop cloth material, 3M

the acrylic acid drop cloth material that drop cloth material, acrylic acid drop cloth material for example can obtain from Avery Dennison or cutting drop cloth material (incise drape material).Yet, will recognize, sealing drop cloth 116 can be formed by any suitable material.In an alternative form, sealing drop cloth 116 can be perforated to allow dampness or steam process to activate contraction elements (below further discussing).Except as otherwise noted, as used herein, "or" does not require mutually exclusive.

One or more contraction elements 118 are coupled in sealing drop cloth 116.Each contraction elements 118 is configured to when being activated, to shrink to produce the closing force (for example the vector in Fig. 3 B or arrow 128 illustrated directions) that can assist wound closure 102.In this illustrative embodiment, contraction elements 118 is in stretch position when wound closure dressing 110 is applied to patient.Contraction elements 118 can be coupled in sealing drop cloth 116 in stretch position, or when wound closure dressing 110 is being applied to patient, can passive movement to stretch position.In both cases, when contraction elements 118 is activated, they attempt to be back to non-stretching or free position, thereby and shrink to produce closing force.Below further describe other illustrative modes of contraction.

Wound closure dressing 110 can comprise by the various contraction elements 118 with many deployment arrangements.For example, as shown in Fig. 1-3B, wound closure dressing 110 can comprise a plurality of contraction elements 118, and each contraction elements 118 is formed as bar.Selectively, wound closure dressing 110 can comprise single contraction elements 118.In another embodiment, one or more contraction elements 118 can be knitted in sealing drop cloth 116 or be knitted into the extra member that is coupled in sealing drop cloth 116, for example, in part of gauze, another drop cloth shape etc.In addition, each contraction elements 118 can include but not limited to welding (for example ultra-sonic welded or radio-frequency welding), binding, machanical fastener, binding agent, cement etc. by any suitable device or technology, is coupled in sealing drop cloth 116.Selectively, each contraction elements 118 can be entered to seal in drop cloth 116 by molding.Contraction elements 118 is coupled in the second surface 124 towards tissue of sealing drop cloth 116 or is coupled in the first surface 122 of sealing drop cloth 116 or is coupled in the interior section that seals drop cloth 116.

Each contraction elements 118 can be formed by any suitable material shrinking in response to being activated.Contraction elements 118 is configured to from extended position, move to punctured position (or free position) when being activated completely.For example, each contraction elements 118 can be formed by cellulose, and dampness shrinks contraction elements 118 thus.Dampness can be introduced into from patient's self transudate.Selectively or additionally, dampness can be before wound closure dressing 110 be applied to patient with fluid for example the mode of water, bacteriostatic water, saline etc. be introduced into wound 102 or wound area.In another alternative form or additional form, sealing drop cloth 116 can be provided with for fluid being introduced to wound area after wound closure dressing 110 has been applied to patient to activate the mouth (not shown) of contraction elements 118.

In another alternative form or additional form, contraction elements 118 can be formed by the shape memory metal shrinking in response to being activated.An example of suitable shape memory metal is from the Nitinol Devices & Components of Fremont's of California material.The contraction elements 118 being formed by shape memory metal can be by heat, and for example patient's body heat, hot plate, thermolamp etc. activate.Selectively or additionally, contraction elements 118 can be activated by the introducing of electromagnetic induction.Yet, to recognize, contraction elements 118 can be formed by any suitable material, includes but not limited to marmem, magnetic shape memory alloy, shape-memory polymer, piezoelectric, electroactive polymer, magneto-rheological fluid and elastomer and ERF.Depend on concrete material, activation can be taked the form of the variation of electric field, variations in temperature, magnetic field, mechanical load or pressure, light, ultraviolet light, environment pH, ultrasonic, dampness etc.

Clamping component 120 helps closing force (being illustrated by arrow 128) that the contraction by contraction elements 118 produces to patient's skin transmission.The power being passed is illustrated as force vector 130 in Fig. 2.Sealing drop cloth 116 and clamping component 120 can concur to form fluid-tight above the wound 102 patient.Consider related concrete Reduced pressure source or subsystem, " fluid-tight " or " sealing " means to be enough to keep at the position of expectation the sealing of decompression.

Clamping component 120 can be any be suitable for by closing force from contraction elements 118 be passed to patient epidermis 104 (patient's epidermis 104 can be regarded as comprising the layer of liner or other materials) material or assist in wound 102 and form fluid-tight.For example, clamping component 120 can be contact adhesive, heat-activatable adhesive, band, dual face seals band, glue, hydrocolloid, hydrogel, hook, suture etc.In this illustrative embodiment, clamping component 120 is adhesive phase and the width towards the second surface 124 of organizing of crossing over sealing drop cloth 116 and overlapping with contraction elements 118.Yet, will recognize, clamping component 120 can only be coupled in the surface towards tissue of drop cloth extension 126.Clamping component 120 can be used as the lamella or the pattern (pattern) that are distributed on sealing drop cloth 116 and is formed.Selectively, for the situation of band, clamping component 120 can be applied on the whole first surface 122 that seals drop cloth 116 or be applied on the first surface of drop cloth extension 126.

Manifold member 112 or manifold can be positioned in sealing drop cloth 116 towards tissue second surface 124 and at least a portion of wound 102 between.Manifold member 112 can be by controlling dimension with the area of the estimation of wound coverage 102 in fact, but in different application, can use larger or less size.Manifold member 112 is manufactured by manifold material.

As used herein term " manifold " typically refers to and is provided to assist material or the structure that applies decompression, transmits fluid or remove fluid from wound 102 to wound 102 to wound 102.Manifold member 112 typically comprises a plurality of flow channels or path, and the plurality of flow channel or path allocation are provided to manifold member 112 wound 102 around and the fluid of being removed by the wound 102 around manifold member 112.In an illustrative embodiment, flow channel or path are connected to each other to improve and are provided or by the distribution of the fluid of removing from wound 102.Manifold member 112 can be can be placed as to contact with wound 102 and to the biocompatible material of wound 102 distribute reduced pressure.The example of manifold member 112 can include but not limited to for example have the device of the structural element that is arranged to form flow channel, for example cellular foam, open celled foam, porous organization's aggregation and comprise or solidify to comprise liquid, gel and the foam of flow channel.Manifold member 112 can be porous and can be suitable for the material manufacture of concrete biological applications by foam, gauze, felting pad or any other.

In one embodiment, manifold member 112 is porous foams and comprises a plurality of interconnected cell or the hole as flow channel.Porous foam can be polyurethanes open mesh foams, and for example, by the Kinetic Concepts of the San Antonio of Texas, Incorporated produces

material.Other embodiments can comprise " closed pore ".Under certain conditions, manifold member 112 can also be for to wound 102 distributing fluids, for example medicine, antibacterial, somatomedin and various solution.In manifold member 112 or in manifold member 112, can comprise other layer, for example absorbent material, capillary material (wicking material), hydrophobic material and water wetted materials.In some cases, can be expectation, in microbonding technique, ionic silver is added to foam in or in manifold member 112, add other materials, antimicrobial for example.Manifold member 112 can be isotropic or anisotropic, depends on the accurate orientation in the desired compression stress of decompression.In addition, manifold material can be bioabsorbable material.

Manifold member 112 can be coupled in sealing drop cloth 116.Coupling can occur in many ways.Sealing drop cloth 116 and manifold member 112 can be used binding agent, and for example acryloid cement, silicone adhesive, hydrogel, hydrocolloid etc. are coupled.Selectively, it is combined that sealing drop cloth 116 and manifold member 112 can be passed through thermal, ultrasound wave combination and radio frequency combination etc.Coupling can pattern form or generation more completely.Structure can be added into joint portion so that sealing drop cloth 116 shows anisotropy in the direction of expectation, manufactures anisotropic drop cloth material.Anisotropic drop cloth material can concur with contraction elements 118, mainly to move in given direction, only around some or a plurality of axis.For example, anisotropic sealing drop cloth can concur to produce closing force to assist wound closure with contraction elements.

Decompression subsystem 114 comprises Reduced pressure source 132, and Reduced pressure source 132 can take a number of different forms.Reduced pressure source 132 provides decompression as a part for reduced-pressure wound treatment systems 100.Reduced pressure source 132 provides decompression.Reduced pressure source 132 can be any for supplying the device of decompression, for example vacuum pump, wall inhaler or other sources.Although being applied in amount and the character of the decompression of tissue site or wound will be typically according to application change, but decompression will be typically-5mmHg between-500mmHg and more typically at-100mmHg between-300mmHg, and more typically at-100mmHg to the scope of-200mmHg.

As used herein, " decompression " typically refers to and is less than through the pressure of the ambient pressure of subject tissue site or site of injury.In most of the cases, this decompression will be less than the atmospheric pressure of patient's part of living in.Selectively, decompression can be less than the hydrostatic pressure of tissue site.Except as otherwise noted, the value of the pressure of statement is gauge pressure herein.The decompression being transmitted can be constant or (regular or random) that change and can be transmitted continuously or off and on.Although can use term " vacuum " and " negative pressure " to describe the pressure that is applied in tissue site, the actual pressure that is applied in tissue site can be greater than the pressure being conventionally associated with absolute vacuum.Consistent with use herein, the rising of decompression or vacuum pressure typically refers to the relative reduction of absolute pressure.

In this illustrative embodiment, Reduced pressure source 132 is shown as the territory, tank field 136 that has cell compartments 134 and have window 138, and window 138 provides the visible indication of the level of the fluid in tank 136.The film filter inserting, for example hydrophobic filter or oleophobic filter, can be interspersed between decompression delivery catheter or pipeline 140 and Reduced pressure source 132.

The decompression being generated by Reduced pressure source 132 is sent to the decompression body 142 of plugging into through decompression delivery catheter 140, and the decompression body 142 of plugging into can be elbow mouth 144.In an illustrative embodiment, elbow mouth 144 is to obtain from the KCI of the San Antonio of Texas

technology mouth (technology port).Plug into body 142 of decompression allows decompression be transferred into wound closure dressing 110 and be implemented in the interior section of wound closure dressing 110 and in manifold member 112.In this illustrative embodiment, elbow mouth 144 extends to manifold member 112 through sealing drop cloth 116.

One or more devices 141 can be added in decompression delivery catheter 140.For example, installing 141 can be for holding the fluid reservoir of transudate and other fluids that are removed or collecting member.Other examples of device 141 that can be included on decompression delivery catheter 140 or otherwise fluidly be coupled in decompression delivery catheter 140 comprise following nonrestrictive example: press feedback device, volume detection system, blood detection system, infection detection system, mobile monitoring system, temperature monitoring system etc.Some in these devices can be formed with Reduced pressure source 132.

In operation, reduced-pressure wound treatment systems 100 can be applied to patient's wound 102.First manifold member 112 is placed in wound 102.Manifold member 112 can be placed in wound 102 or a part that can wound coverage 102.If wound closure dressing 110 is not yet coupled in manifold member 112, so then wound closure dressing 110 can be placed on the top of manifold member 112, and the drop cloth extension 126 that makes to seal drop cloth 116 extends beyond the periphery of wound 102.The clamped member 120 of drop cloth extension 126 is fixed on patient's epidermis 104, to form fluid-tight in wound 102.Then, one or more contraction elements 118 can be activated, and make contraction elements 118 produce contractility (being illustrated by arrow 128), and this contractility is transferred to patient's epidermis 104 by clamping component 120, make wound edge 101 be pulled more closely.

If the decompression body 142 of plugging into is not yet mounted, the decompression body 142 of plugging into is applied so, and decompression delivery catheter 140 is at one end fluidly coupled.The other end of decompression delivery catheter 140 is fluidly coupled in Reduced pressure source 132.Then Reduced pressure source 132 can be activated, and decompression is transmitted to wound closure dressing 110.Advantageously, if contraction elements 118 is activated by the dampness from fluid, as discussed above, applying of decompression can partly work that extra fluid is pulled out and is pulled to contraction elements 118 from the inside of wound closure dressing 110 so.

When pressure is lowered, semirigid substrate is laterally compressed and shunk to form to manifold member 112.Decompression is still transmitted through manifold member 112 further, makes at patient's epidermis 104 places and at wound 102 places, stands decompression.The decompression that is transferred into manifold member 112 can generate the compression stress of stability and therapy 146 can be provided.Compression stress 146 can be not only at the top of epidermis 104; Compression stress 146 can deeper be extended downwards and can be felt at the level place of subcutaneous tissue 108.

When sealing drop cloth 116 and manifold member 112 are laterally shunk under the impact of decompression, and work as downward power and do the used time through the Poisson's ratio of epidermis 104, can generate inside power 148, this inside power 148 can help the closing force that keeps extra in wound 102 and can to wound 102, provide extra stability substantially.Therefore, from the inside power 148 of decompression and from the power 130 of contraction elements 118 can combined effect to assist wound closure 102.Meanwhile, the decompression help that is transmitted and be transmitted through manifold member 112 to manifold member 112 is removed any transudate with other fluids and provides reduced pressure therapy to wound 102 from wound 102.These all effects can improve the healing of wound 102.

With reference to Fig. 3 A, the activation that wound closure dressing 110 is shown in contraction elements 118 is disposed in wound 102 before.Fig. 3 B shows at least three the wound closure dressing 110 of the contraction elements 118 of inner side after having shunk at least in part to provide the closing force being represented by arrow 128.

Can be expectation, administering reduced pressure wound treatment system 100 in operating room, and allow reduced-pressure wound treatment systems 100 to be retained in it patient, until there is enough healings.In this respect, can be expectation, by transparent material, form sealing drop cloth 116, manifold member 112 and any other layer, to allow nursing supplier, obtain the visual cues about wound 102, and do not need to remove wound closure dressing 110.In addition, it will be appreciated that reduced-pressure wound treatment systems 100 can be as main wound closure treatment or the intermediate steps for the treatment of as wound closure.In addition, will recognize, wound closure dressing 110 can not used in the situation that there is no manifold member 112 or decompression subsystem 114.Wound closure dressing 110 can be useful as transmitting closing force and not need the independently binder of decompression to wound 102.

, mainly with reference to Fig. 4 A and 4B, show the illustrative embodiment of wound closure dressing 210 now.Wound closure dressing 210 is similarly with the wound closure dressing 110 of Fig. 1-3B and relevant parts aspect most of, and the dependency of each several part in the present embodiment conventionally by numeral adjustment 100 is represented.For example, sealing drop cloth 216 is similar to sealing drop cloth 116.Although wound closure dressing 210 exists as separated wound closure dressing, wound closure dressing 210 can be used as depressurized system, for example a part for reduced-pressure wound treatment systems 100.Wound closure dressing 210 can be shaped to approach the shape of wound 202 or extend beyond wound 202.Although it is circular in fact that the plane graph of wound closure dressing 210 is shown as, but will recognize, wound closure dressing 210 can have any suitable plane graph, includes but not limited to foursquare, rectangle, leg-of-mutton, oval-shaped, hexagonal, octagonal, irregular etc.Contraction elements 218 can be woven in together with the pattern of " straw mulch (thatched) ", make when being activated, equal in fact closing force (arrow 228 representatives in Fig. 4 B) can be distributed in around the whole periphery 203 of wound 202.Fig. 4 A shows wound closure dressing 210 and the wound 202 before the activation of contraction elements 218, and Fig. 4 B shows wound closure dressing 210 and wound 202 after contraction elements 218 has been activated.

, mainly with reference to Fig. 5, show another the illustrative decompression wound closure system 300 that is used for the treatment of patient's wound 302 with it now.System is similar substantially with the system of the reduced-pressure wound treatment systems 100 of Fig. 1-3B aspect most of.Similarly part is by representing the reference number adjustment 200 of Fig. 1-3B.In this illustrative embodiment, can utilize a plurality of contraction elements 318 and back strap 350.Each contraction elements 318 and corresponding back strap 350 form shrink strip 352.Therefore, can utilize a plurality of shrink strips 352.Each contraction elements 318 is coupled in corresponding back strap 350 separatably.As previously mentioned, contraction elements 318 is configured to shrink when being activated, to produce the closing force that can assist wound closure 302.Contraction elements 318 can be coupled in separatably back strap 350 in stretch position, or when shrink strip 352 is applied to patient, can passive movement to stretch position.In both cases, when contraction elements 318 is activated, contraction elements 318 attempts to be back to non-stretching or free position, thereby and shrinks to produce closing force.

Although illustrative embodiment illustrates each shrink strip 352, there is single contraction elements 318, will recognize, can adopt any suitable number of contraction elements 318.In addition, in the situation that shrink strip 352 comprises a plurality of contraction elements 318, a plurality of contraction elements 318 can relative to each other be arranged with any suitable pattern, for example parallel, vertical, angled etc.Although mentioned a plurality of contraction elements 318, back strap 350 and shrink strip 352, also can use the single member of each.As other embodiments, contraction elements 318 can be formed and can be activated in many ways by any suitable material shrinking in response to being activated.

Back strap 350 can be formed by any suitable material, includes but not limited to gauze, elastomer, binding agent etc.The shrink strip 352 of any suitable number can be placed on wound 302 and manifold member, for example, in the manifold member in Fig. 2 112.Each shrink strip 352 can be fixed on epidermis with any suitable pattern by corresponding clamping component, to assist wound closure 302.Thering is the plug into sealing drop cloth 316 of body 342 of decompression and can be placed on shrink strip 352, making decompression can be transferred into wound 302; Selectively or additionally, shrink strip 352 can be placed on the top of sealing drop cloth 316.In selectable embodiment, the back strap 350 of each shrink strip adopting 352 can be formed by drop cloth material, each back strap 350 concurs with one or more back straps that adjoin 350 thus, thereby shape all-in-one-piece drop cloth is eliminated the needs to extra sealing drop cloth thus; In the present embodiment, can be expectation, use the clamping component (for example binding agent) with high water vapor transfer rate (MVTR).In another selectable embodiment, shrink strip 352 can be for example, as parts (there is no manifold and decompression subsystem) independently to assist wound closure.

, mainly with reference to Fig. 6, show another illustrative nonrestrictive embodiment of the decompression wound closure system 400 that is used for the treatment of wound 402 now.Decompression wound closure system 400 is similar substantially with the reduced-pressure wound treatment systems 100 of Fig. 1-3B aspect most of, and similarly part by the reference number adjustment 300 of Fig. 1-3B is represented.Contraction elements 418 is arranged with " star " pattern, with the periphery 401 to wound 402, transmits equal in fact closing force.Contraction elements 418 comprises medium pore 454, and medium pore 454 is for receiving through the decompression of medium pore 454 body 442 of plugging into.Although illustrative contraction elements 418 is shown as, have eight " supporting legs ", will recognize, contraction elements 418 can comprise the supporting leg of any suitable number and can be used as the unit manufacture of as directed one or be manufactured by a plurality of parts.

Now mainly with reference to Fig. 7 A and Fig. 7 B, Fig. 7 A is the schematic upward view of a part of illustrative embodiment that is used for the treatment of the system of wound.These figure comprise the selectable embodiment for the wound closure dressing 500 of wound closure.Wound closure dressing 500 comprises sealing drop cloth 502, solvable disintegration 504, elastic component 506 and clamping component 508.Wound closure dressing 500 can, as the individual components of auxiliary wound closure, maybe can be used as a part for the depressurized system of auxiliary wound closure and treatment.Sealing drop cloth 502 comprise first surface 510 and towards tissue second surface 512.Sealing drop cloth 502 can be formed and can operate in a similar manner by identical or similar material by the sealing drop cloth 116 with Fig. 1-3B substantially.Selectively, sealing drop cloth 502 can be perforated to allow dampness to lead to solvable disintegration 504 from first surface 510.

Solvable disintegration 504 is coupled in the second surface 512 towards tissue of sealing drop cloth 502.Solvable disintegration 504 can be formed by any suitable soluble material, include but not limited to Biodegradable material or bioabsorbable material, for example polyactide (PLA), lactic acid-ethanol copolymer (poly (lactic-co-glycolic acid)) (PLGA), polyglycolic acid (PGA), polycaprolactone (PCL), sodium chloride or similarly.In addition, solvable disintegration 504 can comprise granule (oxygenated particle) or the antimicrobial particle for reducing the oxidation of infection.Solvable disintegration 504 remains on elastic component 506 in stretch position, and solvable disintegration 504 can be in any suitable factor, includes but not limited to dissolve under dampness, heat, ultrasonic etc. impact.When solvable disintegration 504 is dissolved, elastic component 506 is discharged at least in part, produces thus closing force, because elastic component 506 attempts to return not stretch position.Although illustrative embodiment shows single solvable disintegration 504, will recognize, can adopt any suitable number (seeing for example Fig. 8-9B) of solvable disintegration.

Elastic component 506 is coupled in solvable disintegration 504 in stretch position, makes when solvable disintegration 504 or one are partly dissolved, and elastic component 506 shrinks to produce closing force.Elastic component 506 can include but not limited to that binding agent, machanical fastener, binding, sonic soldering connect etc. by any suitable device or technology, is coupled in solvable disintegration 504.Selectively or additionally, elastic component 506 can be coupled by will elastic component 506 embedding in solvable disintegration 504.Elastic component 506 can be any suitable material that can be coupled in solvable disintegration 504 and can shrink when at least a portion of solvable disintegration 504 is dissolved in stretch position.Such as but not limited to, elastic component 506 can be formed by elastomer.As used herein, term " coupling " comprises by the coupling of separated object and comprises direct-coupling.Term " coupling " also comprises that two or more parts are formed by same one piece material by means of each in parts and is continuous each other.In addition, term " coupling " can comprise (for example passing through chemical bond), machinery, heat or the electric coupling of chemistry.Coupling can also comprise a Component Embedding in another.

As being clearly shown that in Fig. 7 B, elastic component 506 has circular in fact cross section in this illustrative embodiment.Yet, it will be appreciated that elastic component 506 can have any suitable cross section.In addition, will recognize, elastic component 506 can have any suitable configuration.For example, elastic component 506 can be arranged to " straw mattress " pattern, cross pattern, parallel pattern etc.In addition, although illustrative embodiment shows single elastic component 506, will recognize, the elastic component 506 of any suitable number can be coupled in one or more solvable disintegration 504.In addition, the end of elastic component 506 can be coupled in sealing drop cloth 502, makes the contractility being produced by elastic component 506 can be directly passed to clamping component 508 (as discussed further below).

Clamping component 508 is identical or similar with the clamping component 120 of the reduced-pressure wound treatment systems 100 of Fig. 1-3B.Clamping component 508 can be coupled at least one in sealing drop cloth 502, solvable disintegration 504 or elastic component 506.The epidermis that the power that clamping component 508 is configured to that the contraction by elastic component 506 is produced is passed to patient is to assist wound closure.Selectively, as illustrated best in Fig. 7 B, wound closure dressing 500 also can comprise perforated sheets 514, and perforated sheets 514 is disposed between solvable disintegration 504 and wound, to regulate the amount of dampness of transudate that is allowed to reach solvable disintegration 504 from patient.The amount of the in the situation that this dissolving when dampness is introduced into solvable disintegration 504 for solvable disintegration 504 therein, solvable disintegration 504 being dissolved or the control of speed, can be useful.

, mainly with reference to Fig. 8-9B, show the wound closure dressing 610 that another is used for the treatment of wound 602 now.Wound closure dressing 610 is similar substantially with the wound closure dressing 500 of Fig. 7 A and 7B aspect most of.Similarly part is by representing the reference number adjustment 100 of Fig. 7 A and 7B.In the present embodiment, solvable disintegration 604 comprises a plurality of solubilized pearls 618 or other soluble members.A plurality of solubilized pearls 618 keep the power being produced by the elastic component 606 stretching, and if a plurality of solubilized pearl 618 is dissolved, the clamping component (not shown) that attaches to so elastic component 606 stands the power raising.Pearl 618 is typically dissolved by the transudate from wound 602.When pearl 618 is dissolved, the contractility being produced by corresponding elastic component 606 increases.The closing force producing can have direct relation with the number of dissolved pearl 618.For example, when the number of dissolved pearl 618 increases, the closing force producing can be with the relation of determining, increases for example linearly, exponentially etc.

Therefore,, as being clearly shown that in Fig. 9 A and 9B, wound closure dressing 610 can be " tuned " with the wider part place in wound 602 and produce larger closing force.In addition, this can occur in self-regulating mode.In other words, the region of the level of the rising with transudate of wound 602, the wider part of wound 602 typically, stands larger closing force, because the level of the rising of transudate causes more pearl 618 to be dissolved, this has increased the closing force being produced by elastic component 606.Wound closure dressing 610 can with the sealing drop cloth of wound closure dressing 510 similar in appearance to Fig. 7 A and 7B and clamping component and as sealing drop cloth and the clamping component of the part of Reduced pressure treatment system, jointly use.Selectively, each end of each elastic component 606 can be fixed in patient's epidermis and be used as the wound closure dressing 610 for the independent dressing of auxiliary wound closure.

Although in the context of some illustrative non-limiting embodiments, disclose the present invention with and advantage, but should be appreciated that and can make various changes, replacement, displacement and change and not depart from scope of the present invention defined by the appended claims.It should be understood that the feature of describing in conjunction with any one embodiment also goes for any other embodiment.

Claims

1. a reduced-pressure wound treatment systems that is used for the treatment of patient's wound with it, described system comprises:

Wound closure dressing, it comprises:

Sealing drop cloth, it has first surface and towards the surface of organizing, described sealing drop cloth is used for being placed on wound,

Contraction elements, it is coupled in described sealing drop cloth, and described contraction elements is configured to when being activated, shrink and produce thus closing force,

Clamping component, it is coupled in described sealing drop cloth, and described clamping component is configured to the epidermis to patient by described closed force transfer, and wherein said sealing drop cloth and described clamping component are configured to form fluid-tight in described wound;

Manifold member, it is for being arranged in the described towards between the surface and described wound of tissue of described sealing drop cloth; And

Decompression subsystem, it is for transmitting decompression to described wound closure dressing.

2. system according to claim 1, wherein said contraction elements is configured to move to punctured position from extended position, and wherein said contraction elements is initially in described extended position.

3. system according to claim 1, wherein said contraction elements is by hot activation.

4. system according to claim 1, wherein said contraction elements is activated by dampness.

5. system according to claim 1, wherein said contraction elements is activated by electromagnetic induction.

6. system according to claim 1, wherein said contraction elements comprises a plurality of shrink strips.

7. system according to claim 1, wherein said clamping component comprises binding agent.

8. system according to claim 1, also comprises the solvable disintegration that is coupled in described contraction elements, and wherein said contraction elements is activated when at least a portion of described solvable disintegration is dissolved.

9. system according to claim 1, also comprises the solvable disintegration that is coupled in described contraction elements, and wherein said contraction elements is activated when at least a portion of described solvable disintegration is dissolved, and wherein said solvable disintegration comprises a plurality of solubilized pearls.

10. system according to claim 1, wherein said contraction elements is coupled in the described surface towards tissue of described sealing drop cloth.

11. systems according to claim 1, wherein said contraction elements comprises by the material that is stretched to tensile elongation and is dried from drift, and wherein said contraction elements is activated by dampness.

12. systems according to claim 1, wherein said contraction elements comprises the memory metal that is stretched to stretch position, and wherein said contraction elements is by the hot activation from patient.

13. systems according to claim 1, wherein said contraction elements comprises by the material that is stretched to tensile elongation and is dried from drift;

Wherein said contraction elements is activated by dampness; And

Wherein said clamping component comprises adhesive phase.

14. 1 kinds of methods of manufacturing wound closure dressing, comprise the following steps:

Formation have first surface and towards tissue surperficial sealing drop cloth;

Contraction elements is coupled in to described sealing drop cloth, thereby wherein said contraction elements is configured to from extended position, be contracted to punctured position and produce closing force when being activated;

Clamping component is coupled in to described sealing drop cloth, makes described clamping component be configured to the epidermis to patient by described closed force transfer; And

Manifold member is coupled in to the described surface towards tissue of described sealing drop cloth.

15. methods according to claim 14, also comprise solvable disintegration are coupled in to described contraction elements, and described contraction elements is activated when at least a portion of described solvable disintegration is dissolved.

16. methods according to claim 14, also comprise a plurality of contraction elements are coupled in to described sealing drop cloth.

17. methods according to claim 14, also comprise decompression subsystem are fluidly coupled in to described sealing drop cloth.

18. methods according to claim 14, the step that wherein contraction elements is coupled in to described sealing drop cloth comprises that coupling has the contraction elements of a plurality of solubilized pearls.