CN102125717B - Biliary tract internal drainage tube carrying radioactive particles - Google Patents
Biliary tract internal drainage tube carrying radioactive particles Download PDFInfo
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- CN102125717B CN102125717B CN 201110087418 CN201110087418A CN102125717B CN 102125717 B CN102125717 B CN 102125717B CN 201110087418 CN201110087418 CN 201110087418 CN 201110087418 A CN201110087418 A CN 201110087418A CN 102125717 B CN102125717 B CN 102125717B
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- drainage tube
- lumen
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- biliary
- radioactive particles
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- 239000002245 particle Substances 0.000 title claims abstract description 32
- 230000002285 radioactive effect Effects 0.000 title claims abstract description 27
- 210000003445 biliary tract Anatomy 0.000 title description 15
- 239000000463 material Substances 0.000 claims abstract description 6
- 230000003902 lesion Effects 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 abstract description 7
- 230000008901 benefit Effects 0.000 abstract description 6
- 238000012545 processing Methods 0.000 abstract description 4
- 206010028980 Neoplasm Diseases 0.000 description 7
- 201000011510 cancer Diseases 0.000 description 6
- 230000008859 change Effects 0.000 description 5
- 206010023129 Jaundice cholestatic Diseases 0.000 description 4
- 201000005267 Obstructive Jaundice Diseases 0.000 description 4
- 238000007459 endoscopic retrograde cholangiopancreatography Methods 0.000 description 4
- 230000003211 malignant effect Effects 0.000 description 4
- 230000004083 survival effect Effects 0.000 description 4
- 210000000013 bile duct Anatomy 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000001959 radiotherapy Methods 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 210000004881 tumor cell Anatomy 0.000 description 3
- 201000009030 Carcinoma Diseases 0.000 description 2
- 206010027476 Metastases Diseases 0.000 description 2
- 239000003708 ampul Substances 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 206010056375 Bile duct obstruction Diseases 0.000 description 1
- 206010008635 Cholestasis Diseases 0.000 description 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 description 1
- 230000003872 anastomosis Effects 0.000 description 1
- 238000002725 brachytherapy Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 201000010175 gallbladder cancer Diseases 0.000 description 1
- 201000007487 gallbladder carcinoma Diseases 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000001665 lethal effect Effects 0.000 description 1
- 210000001165 lymph node Anatomy 0.000 description 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000002638 palliative care Methods 0.000 description 1
- 238000009116 palliative therapy Methods 0.000 description 1
- 208000016853 pontine tegmental cap dysplasia Diseases 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011470 radical surgery Methods 0.000 description 1
- 208000037803 restenosis Diseases 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
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Abstract
本发明所述的携带放射性粒子胆道内引流管，涉及医疗器械技术领域，是一种可承载微型放射性粒子源的胆道内引流支架。是由引流管及固定倒刺所组成；其特征在于在引流管的内壁上加工有管腔容器，管腔容器内加工有管腔阁；各个管腔阁之间由单向瓣膜阀相隔，每个管腔阁上都加工有标记点，标记点为不透射线材料制成；在引流管的管壁外加工有所述固定倒刺；根据引流管插入病灶的位置，在相对应的管腔阁内装入可随时更换的放射性粒子。本发明具有结构新颖、加工简便、成本低廉、使用方便、安全可靠、操作简单、治疗效果明显等优点，故属于一种集经济性与实用性为一体的新型携带放射性粒子胆道内引流管。
The biliary internal drainage tube carrying radioactive particles of the present invention relates to the technical field of medical devices, and is a biliary internal drainage stent capable of carrying miniature radioactive particle sources. It is composed of a drainage tube and a fixed barb; it is characterized in that a lumen container is processed on the inner wall of the drainage tube, and a lumen cabinet is processed in the lumen container; each lumen cabinet is separated by a one-way valve valve, each Marking points are processed on each lumen pavilion, and the marking points are made of radiopaque materials; the fixed barbs are processed outside the tube wall of the drainage tube; The cabinet is filled with radioactive particles that can be replaced at any time. The invention has the advantages of novel structure, simple processing, low cost, convenient use, safety and reliability, simple operation, obvious therapeutic effect, etc., so it belongs to a new type of biliary drainage tube carrying radioactive particles integrating economy and practicability.
Description
Technical field
The radioactive particle biliary tract inner drainage tube that carries of the present invention relates to technical field of medical instruments, but is the interior drainage stent of biliary tract in a kind of bearing micro radioactive particle source.
Background technology
At present malignant obstructive jaundice comprises that one group of malignant tumor hepatic portal portion hepatocarcinoma, cancer of biliary duct, cancer of pancreas, carcinoma of ampulla and portal lymph node that causes obstruction of bile duct shifts, oppresses or invade and bile duct etc.Because how this type of case has lost the surgical engine meeting when making a definite diagnosis, excision rate 15%～20% is appeased the partial flow bypass path art and is only applicable to 19% case.Development from phase early 1990s along with the inner support technology, home and abroad extensively adopt ERCP to appease method treatment malignant obstructive jaundice, and clinical effectiveness is satisfied, and make needed the case of simple biliary enteric anastomosis 70% to be replaced by ERCP in the past.But because malignant tumor itself is not effectively treated, restenosis or neoplasm metastasis often take place, the median survival interval of most statistics is 5～12 months, therefore, during the ERCP that is expert at treatment, should carry out the oncotherapy of protopathy as far as possible simultaneously.
Mainly divide two kinds through duodenoscope biliary drainage art, a kind of is bile duct plastic stent drainage (Endoscopic retrograde biliarydrainge under the scope, ERBD), another kind be bile duct metal rack drainage under the scope (Endoscopic biliary metal stent drainge, EBMSD).Preceding a kind of method is at first by German Soehendra report, it is safe and reliable, anacholia is lost, more meet physiological status, postoperative also need not special care, has greatly improved patient's quality of life, simultaneously the malignant tumor patient that advanced age, the biliary tract patient especially can't excise that operation is had a big risk, be a kind of means of palliative therapy preferably, be extensive use of clinical at present.
125I corpuscular radiation source can be positioned over inside tumor or near, tumor tissues can be subjected to heavy dose of radiation exposure around the particle, reach therapeutic purposes, and because the effective irradiation distance of particle is short, the normal surrounding tissue radioactive dose far away from particle obviously reduces, particle is a solid implant simultaneously, does not participate in general metabolism, and is less to the overall health of patients influence.Therefore the 125I internal-radiation therapy can not only reach the therapeutic purposes of kill tumor cell, and to the little advantage of tumor normal surrounding tissue damage, protection normal structure and organ are avoided the ultrahigh dose irradiation.On the other hand, the 125I particle is a kind of radionuclide of lasting low dose exposure, does not have the specific cytosis cycle, and the tumor cell of each phase is all had certain lethal effect, be subjected to the ray prolonged exposure and obviously minimizing thereby make tumor cell breed again, can reduce the recurrence of tumor.
Employing PTCD technology supports such as Bruha are inserted in one group of malignant obstructive jaundice case of binding cavity internal radiotherapy, 1 year survival rate of cancer of biliary duct patient reaches 47%, 1 year survival rate of carcinoma of ampulla patient reaches 75%, and 1 year survival rate of carcinoma of gallbladder patient has then reached 18%, has received good effect.
Malignant obstructive jaundice is the clinical disease that often runs into, but when patient's whole body situation can not tolerate the existing metastasis of radical surgery or tumor, the emphasis of treatment should be and keeps biliary drainage unobstructed, alleviates patient's complication, improves its life quality.But, only go the interior drain (ERBD/EBMSD) of the interior drainage stent of biliary tract also just to the palliative treatment of malignant tumor, be equivalent to drainage.Biliary tract rack implantation associating (125I) radioactive particle intra cavitary irradiation is as a kind of brand-new treatment means, combine the characteristics of ERCP and brachytherapy, combine the advantage of the two, complication that obstruction of biliary tract causes but also the effect of having played treatment had not only been solved, patient's misery is little, quality of life height, the minimizing of exposure dose reduces the side reaction that patient causes because of radiotherapy greatly, really having embodied the theory of minimally-invasive treatment, is the research topic that has development prospect.
Still there is not drainage stent in the biliary tract that can carry (125I) radioactive particle at present.A kind of novel radioactive particle biliary tract inner drainage tube that carries of research design, existing problem is very necessary in the prior art thereby overcome.
Summary of the invention
In view of existing problem in the above-mentioned prior art, the objective of the invention is a kind of novel radioactive particle biliary tract inner drainage tube that carries of research design.In order to solve drainage stent problem in the biliary tract that does not carry radioactive particle that exists in the prior art.
Technical solution of the present invention is achieved in that
The radioactive particle biliary tract inner drainage tube that carries of the present invention, by drainage tube and fixedly agnail formed; It is characterized in that on the inwall of drainage tube, being processed with the tube chamber container, be processed with the tube chamber pavilion in the tube chamber container; Be separated by by the one-way valve valve between each tube chamber pavilion, all be processed with gauge point on each tube chamber pavilion; State fixedly agnail to some extent in the outer processing of the tube wall of drainage tube; According to the position that drainage tube inserts focus, the radioactive particle of in corresponding tube chamber pavilion, packing into and can change at any time.
Gauge point of the present invention is made for the radiopaque material.
To carry radioactive particle biliary tract inner drainage tube by the duodenoscope technology through nature tract (per os, esophagus, gastroduodenal) Wicresoft inserts in the biliary tract, can change again through scope when after particle reaches the half-life, needing to treat again, have characteristics such as Wicresoft, safety, repeatability are strong.
Advantage of the present invention is conspicuous, mainly shows:
1, owing to be processed with fixedly agnail on the drainage tube of the present invention, makes the drainage tube position stability and difficult drop-off;
2, because the present invention places the tube chamber pavilion with radioactive particle, and there is the one-way valve valve to stop at interval, can not cause because of coming off of radioactive particle and reduce therapeutic effect or cause the damage of health tissues;
3, because the present invention places the tube chamber pavilion with radioactive particle, can place required radioactive particle quantity according to the concrete condition of focus, make treatment reach optimum efficiency;
4, owing to place radioactive particle in the tube chamber of the tangible drainage tube of the present invention, can change at any time, reach better therapeutic effect according to treatment cycle and therapeutic effect;
5, owing to be processed with the radio opaque markers point on the tube chamber pavilion of the present invention, make the treatment location more accurate;
6, material required for the present invention all is the stock that current medical treatment consumptive materials is made, and is with low cost, cost is low.
The present invention has advantages such as novel structure, processing is easy, with low cost, esy to use, safe and reliable, simple to operate, therapeutic effect is obvious, and it puts goods on the market in enormous quantities and will produce positive social benefit and remarkable economic efficiency.
Description of drawings
The present invention has 2 width of cloth accompanying drawings, wherein:
Accompanying drawing 1 is a structural representation of the present invention;
Accompanying drawing 2 is a schematic perspective view of the present invention.
In the drawings: 1, drainage tube 2, tube chamber container 3, fixedly agnail 4, gauge point 5, one-way valve valve 6, tube chamber pavilion 7, radioactive particle.
The specific embodiment
Specific embodiments of the invention as shown in drawings, by drainage tube 1 and fixedly agnail 3 formed; It is characterized in that on the inwall of drainage tube 1, being processed with tube chamber container 2, be processed with tube chamber pavilion 6 in the tube chamber container 2; Be separated by by one-way valve valve 5 between each tube chamber pavilion 6, all be processed with gauge point 4 on each tube chamber pavilion; State fixedly agnail 3 to some extent in the outer processing of the tube wall of drainage tube 1; According to the position that drainage tube 1 inserts focus, the radioactive particle 7 of in corresponding tube chamber pavilion 6, packing into and can change at any time.
The above; it only is the preferable specific embodiment of the present invention; but protection scope of the present invention is not limited thereto; all are familiar with those skilled in the art in technical scope disclosed by the invention, are equal to replacement or change and all should be encompassed within protection scope of the present invention according to technical scheme of the present invention and design of the present invention thereof.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110087418 CN102125717B (en) | 2011-04-07 | 2011-04-07 | Biliary tract internal drainage tube carrying radioactive particles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110087418 CN102125717B (en) | 2011-04-07 | 2011-04-07 | Biliary tract internal drainage tube carrying radioactive particles |
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| Publication Number | Publication Date |
|---|---|
| CN102125717A CN102125717A (en) | 2011-07-20 |
| CN102125717B true CN102125717B (en) | 2013-07-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 201110087418 Expired - Fee Related CN102125717B (en) | 2011-04-07 | 2011-04-07 | Biliary tract internal drainage tube carrying radioactive particles |
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Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX366156B (en) | 2013-03-14 | 2019-06-28 | Bard Inc C R | Brachytherapy seed insertion and fixation system. |
| CN103784157A (en) * | 2014-02-14 | 2014-05-14 | 王葆春 | Device for accurately positioning diseased region of large intestine |
| CN103877675B (en) * | 2014-02-21 | 2016-01-06 | 牛洪欣 | Intraluminal radiotherapy particle implantation device |
| CN103830836A (en) * | 2014-03-03 | 2014-06-04 | 李玉亮 | Drainage catheter capable of carrying radioactive particles |
| CN103933654B (en) * | 2014-04-16 | 2016-07-06 | 南京微创医学科技股份有限公司 | A kind of self-inflated plastic stent and inserter |
| CN104056344B (en) * | 2014-07-19 | 2016-03-23 | 牛洪欣 | Medical treatment particle conduit |
| CN104353189B (en) * | 2014-11-07 | 2018-02-23 | 滕皋军 | The accurate intracavitary radiotherapy method of 3 D stereo and its system for treating tumour |
| CN106512197B (en) * | 2016-11-21 | 2023-11-07 | 窦春青 | Radioactive lumen stent |
| CN109395258A (en) * | 2017-08-18 | 2019-03-01 | 盖炜 | Precise radiotherapy method and system based on sorghum procyanidins |
| CN108785777B (en) * | 2018-03-22 | 2020-11-17 | 丽水市人民医院 | Prevent peritoneal dialysis catheter of aversion |
| CN108325062B (en) * | 2018-03-27 | 2024-01-30 | 郑州大学第一附属医院 | Biliary tract stent particle loading and unloading device |
| CN109224256A (en) * | 2018-11-22 | 2019-01-18 | 上海市东方医院 | The nose bile drainage tube of anti-thelorrhagia and its application |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100030127A1 (en) * | 2006-09-21 | 2010-02-04 | The Second Military Medical University | Duct stent for carrying miniature radioactive particle sources |
| CN101455877A (en) * | 2007-12-12 | 2009-06-17 | 路筝 | Design method of pipe holder capable of bearing micro radioactive particles |
| CN101695458A (en) * | 2009-10-30 | 2010-04-21 | 南京微创医学科技有限公司 | Biliary tract radiation treatment stent |
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| CN102125717A (en) | 2011-07-20 |
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