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CN102093754A - Dyeing agent for labeling skin - Google Patents

Dyeing agent for labeling skin Download PDF

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Publication number
CN102093754A
CN102093754A CN2010105773879A CN201010577387A CN102093754A CN 102093754 A CN102093754 A CN 102093754A CN 2010105773879 A CN2010105773879 A CN 2010105773879A CN 201010577387 A CN201010577387 A CN 201010577387A CN 102093754 A CN102093754 A CN 102093754A
Authority
CN
China
Prior art keywords
staining agent
skin
dye
red
agent according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010105773879A
Other languages
Chinese (zh)
Inventor
钟辉
王普慧
邹传品
孟祥燕
刘利辉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PLA 63975 ARMY
Original Assignee
PLA 63975 ARMY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PLA 63975 ARMY filed Critical PLA 63975 ARMY
Priority to CN2010105773879A priority Critical patent/CN102093754A/en
Publication of CN102093754A publication Critical patent/CN102093754A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a dyeing agent for labeling skin, which comprises a biological dye, a fluorescent dye, assistants and a solvent. The dyeing agent for labeling skin can be used for dyeing and labeling skin; and the dyeing agent for labeling skin appears vivid rose red under visible light, and appears intense fluorescent under ultraviolet light, and has high color fastness. The invention also relates to a method for identifying a label of a specific target (human or animal). After being spread or sprayed on the skin surface of the specific target, the dyeing agent can not be easily removed in a short time because of the high tinting strength, thereby providing reference for later identification and recognition. The dyeing agent can be used for medical treatment, personal protection, criminal identification and the like, and is available within the temperature range of -30-50 DEG C.

Description

A kind of staining agent that is used for mark skin
Technical field
The present invention relates to a kind of staining agent that is used for mark skin, this staining agent shows bright-coloured rose under visible light, and shows intense fluorescence under UV-light, can be used for aspects such as therapeutic treatment, personal protection, criminal's identification.
Background technology
The skin marker staining agent is used for the mark of skin and identification.Domestic less to this staining agent report, only be used for the medical science aspect; More abroad to this research, be used for aspects such as therapeutic treatment, personal protection, criminal's identification more.
Chinese patent 1486676A has introduced a kind of medical skin mark pen and manufacture method thereof, its ink is made by dihydroxy-benzene, magenta, liquefied phenol, ethanol, acetone adding distil water, is used for the accurate location to operative incision, with the tincture of iodine, alcohol disinfecting, can not fade, can not cause cross infection.This invention only is used for the therapeutic treatment aspect, and does not possess fluorescence, and range of application is narrower.
United States Patent (USP) 5084097 discloses a kind of sprays that is used for self-protection and helps identification, and this sprays is made up of food grade dyes, formaldehyde, water, penetration-assisting agent etc., but owing to use formaldehyde in the prescription, skin is produced pungency.This staining agent color is green, can not show fluorescence under UV-light, can not satisfy many-sided demand.
United States Patent (USP) 4219438 discloses a staining agent invention that is used for mark and identification, this composition comprises a kind of quinazoline fluorescent substance, toluene, dimethylbenzene, Synolac etc., this staining agent only shows fluorescence under UV-light, colourless under the visible light, and use benzene-like compounds in forming, toxicity is bigger.
Summary of the invention
The object of the invention is to overcome the weak point that exists in the above-mentioned technology, provides a kind of and both presents bright-colored under visible light, shows intense fluorescence again under UV-light, and has the skin marker staining agent of higher dyefastness.
The technical solution used in the present invention is: select biological dye, fluorescence dye, auxiliary agent and solvent for use, its set of dispense is such as following:
0.5~2.5 part of biological dye
0.5~2.5 part of fluorescence dye
1~10 part of auxiliary agent
85~98 parts of solvents
More than each component sum be 100 parts.
Biological dye of the present invention is that toluylene red, orange N, sarranine premium T, eosin, alizarin red S, acid Network are red, magenta, algae are red, in the phenodin, phenolsulfonphthalein, pink, the pink RC 01 of media, rhodamine B, bright red 4RC 82 one or more.
Fluorescence dye is one or more in fluorescent yellow, furanone, the amino vanillin food grade,1000.000000ine mesh.
Auxiliary agent is one or more of spearmint oil, borneol, oleic acid, azone.
Solvent is one or more of methyl alcohol, ethanol, Virahol, propylene glycol, glycol ether, acetone, water.
Preparation method of the present invention is as follows: under-30 ℃~50 ℃ temperature, take by weighing each component by the component proportion speed, mechanically mixing evenly can make this staining agent.
Skin marker staining agent involved in the present invention, can under visible light, show bright-coloured rose, can under UV-light, show intensive fluorescence again, at the skin surface strong coloring force, with common washing methods, as suds, ethanol, repeated multiple times such as aqueous sodium hypochlorite solution washings all can not thoroughly be eliminated color and fluorescence, thereby serves as a mark and discern.
Skin marker staining agent involved in the present invention, the use temperature scope is at-30 ℃~50 ℃.
Embodiment
Embodiment 1
Embodiment 1 is a comparative examples, adopts biological dye to prepare staining agent.
Take by weighing 2 parts of magentas, 5 parts of borneols, 60 parts of ethanol, 33 parts in water.Finish through mixing preparation.
As the dyeing object, test Color with commercially available pigskin.
The staining agent for preparing evenly is coated in the pigskin surface, place 60min, wash with suds, ethanol, 5% aqueous sodium hypochlorite solution respectively, through overtesting, magenta is in the obfuscation of pigskin surface color, and not bright-coloured, suds, ethanol all can not be removed its color fully, but it is relatively poor that its anti-chlorine floats colour fastness, and 5% aqueous sodium hypochlorite solution can thoroughly be bleached the magenta color.Under the UV-light a little less than the fluorescence.
Embodiment 2
Embodiment 2 is a comparative examples, adopts biological dye to prepare staining agent.
Take by weighing 2 parts of eosins, 5 parts of borneols, 60 parts of ethanol, 33 parts in water.Finish through mixing preparation.
Test method is with embodiment 1.
Through overtesting, eosin is bright-coloured at the pigskin surface color, but inclined to one side pink colour is more shallow.Suds, ethanol, 5% aqueous sodium hypochlorite solution all can not be removed it fully.Under the UV-light a little less than the fluorescence.
Embodiment 3
Embodiment 3 is a comparative examples, adopts fluorescence dye to prepare staining agent.
Take by weighing 2 parts of aminocoumarins, 5 parts of borneols, 60 parts of ethanol, 33 parts in water.Finish through mixing preparation.
Test method is with embodiment 1.
The apparent no color of this staining agent.The staining agent for preparing evenly is coated in the pigskin surface, places 60min, this staining agent can not be in the pigskin surface colour, but under UV-light visible intense fluorescence.Wash with suds, ethanol, 5% aqueous sodium hypochlorite solution respectively, observe its fluorescence property under the 360nm UV-light, test is found, respectively after suds, ethanol, the washing of 5% aqueous sodium hypochlorite solution, still as seen than hyperfluorescence.
Embodiment 4
Take by weighing 0.5 part of magenta, 0.5 part of eosin, red 0.5 part of algae, 0.2 part of orange N, 0.3 part of aminocoumarin, 2 parts of borneols, 3 parts of azones, 30 parts of ethanol, 30 parts of propylene glycol, 33 parts in water.Finish through mixing preparation.
Make the dyeing object with the live body rabbit ears, the test Color.
The above-mentioned staining agent of preparing is applied on the rabbit ears, and the visible stain agent presents bright-coloured rose on the rabbit ear.Under the 360nm UV-light, intense fluorescence is arranged, on dye 24h after, clean through suds, ethanol and 5% aqueous sodium hypochlorite solution successively, still present bright-coloured rose on the rabbit ear, under the UV-light, still have stronger fluorescence to show on the rabbit ear.
Embodiment 5
The staining agent that embodiment 4 is prepared is placed on 24h in-30 ℃ the refrigerator, take out, test by embodiment 1 method, this staining agent still shows bright-coloured rose on the pigskin surface, under the 360nm UV-light, intense fluorescence is arranged, clean through suds, ethanol and 5% aqueous sodium hypochlorite solution successively behind the coating 60min, the pigskin surface still has obvious color to show that stronger fluorescence is still arranged under the UV-light.
Embodiment 6
The staining agent heating in water bath to 50 that embodiment 4 is prepared ℃, constant temperature 1h, take out, test by embodiment 1 method, this staining agent still shows bright-coloured rose on the pigskin surface, under the 360nm UV-light intense fluorescence is arranged, and cleans through suds, ethanol and 5% aqueous sodium hypochlorite solution successively behind the coating 60min, the pigskin surface still has obvious color to show that stronger fluorescence is still arranged under the UV-light.

Claims (8)

1. a staining agent that is used for mark skin is characterized in that this staining agent comprises biological dye, fluorescence dye, auxiliary agent and solvent, and its set of dispense is such as following:
0.5~2.5 part of biological dye
0.5~2.5 part of fluorescence dye
1~10 part of auxiliary agent
85~98 parts of solvents
More than each component sum be 100 parts.
2. staining agent according to claim 1 is characterized in that biological dye is that toluylene red, orange N, sarranine premium T, eosin, alizarin red S, acid Network are red, magenta, algae are red, in the phenodin, phenolsulfonphthalein, pink, the pink RC 01 of media, rhodamine B, bright red 4RC 82 one or more.
3. staining agent according to claim 1 is characterized in that fluorescence dye is one or more in fluorescent yellow, furanone, the amino vanillin food grade,1000.000000ine mesh.
4. staining agent according to claim 1 is characterized in that auxiliary agent is one or more of spearmint oil, borneol, oleic acid, azone.
5. staining agent according to claim 1 is characterized in that solvent is one or more of methyl alcohol, ethanol, Virahol, propylene glycol, glycol ether, acetone, water.
6. staining agent according to claim 1 is characterized in that described staining agent shows bright-coloured rose under visible light.
7. staining agent according to claim 1 is characterized in that described staining agent shows intense fluorescence under 210nm~650nm UV-light.
8. staining agent according to claim 1 is characterized in that the preparation method of this staining agent is as follows: under-30 ℃~50 ℃ temperature, take by weighing each component by the component proportion speed, mechanically mixing evenly can make this staining agent.
CN2010105773879A 2010-12-08 2010-12-08 Dyeing agent for labeling skin Pending CN102093754A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010105773879A CN102093754A (en) 2010-12-08 2010-12-08 Dyeing agent for labeling skin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2010105773879A CN102093754A (en) 2010-12-08 2010-12-08 Dyeing agent for labeling skin

Publications (1)

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CN102093754A true CN102093754A (en) 2011-06-15

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103483869A (en) * 2013-09-12 2014-01-01 无为县荣华鬃刷制品有限公司 Recipe for mane brown coloring agent
CN104479455A (en) * 2014-12-18 2015-04-01 陈林 Marking liquid specially used for radiotherapy and marking pen applying marking liquid
CN105409888A (en) * 2015-10-30 2016-03-23 成都市白蚁防治研究所 Method for marking termites by staining
CN106320000A (en) * 2016-08-18 2017-01-11 福建省华普新材料有限公司 Fluorescent dye for spinning
CN114441271A (en) * 2021-12-27 2022-05-06 桂林优利特医疗电子有限公司 Preparation of novel dyeing liquid and dyeing method

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4610806A (en) * 1982-10-19 1986-09-09 Rosen Gerald M Skin-marking compositions and devices, and their use
US5084097A (en) * 1990-01-18 1992-01-28 Mccreary A James Aerosol spray for self protection and identification of assailants
CN1408798A (en) * 2001-09-21 2003-04-09 伊利诺斯器械工程公司 Fluorescent mark coloring agent and pencil
CN1486676A (en) * 2002-09-30 2004-04-07 余 张 Medical skin mark pen and its production process
CN1788057A (en) * 2003-03-13 2006-06-14 录象射流技术公司 Ink jet ink composition and method for security making
CN1989220A (en) * 2004-06-22 2007-06-27 皮特尼鲍斯股份有限公司 Ir absorbing photosensitive optically variable ink compositions and process
WO2010126883A1 (en) * 2009-04-27 2010-11-04 Georgia Tech Research Corporation Durable skin marking compositions

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4610806A (en) * 1982-10-19 1986-09-09 Rosen Gerald M Skin-marking compositions and devices, and their use
US5084097A (en) * 1990-01-18 1992-01-28 Mccreary A James Aerosol spray for self protection and identification of assailants
CN1408798A (en) * 2001-09-21 2003-04-09 伊利诺斯器械工程公司 Fluorescent mark coloring agent and pencil
CN1486676A (en) * 2002-09-30 2004-04-07 余 张 Medical skin mark pen and its production process
CN100379390C (en) * 2002-09-30 2008-04-09 张余 Medical skin mark pen and its production process
CN1788057A (en) * 2003-03-13 2006-06-14 录象射流技术公司 Ink jet ink composition and method for security making
CN1989220A (en) * 2004-06-22 2007-06-27 皮特尼鲍斯股份有限公司 Ir absorbing photosensitive optically variable ink compositions and process
WO2010126883A1 (en) * 2009-04-27 2010-11-04 Georgia Tech Research Corporation Durable skin marking compositions

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103483869A (en) * 2013-09-12 2014-01-01 无为县荣华鬃刷制品有限公司 Recipe for mane brown coloring agent
CN104479455A (en) * 2014-12-18 2015-04-01 陈林 Marking liquid specially used for radiotherapy and marking pen applying marking liquid
CN104479455B (en) * 2014-12-18 2016-11-30 陈林 Radiotherapy special marker liquid and use the marker pen of this marking fluid
CN105409888A (en) * 2015-10-30 2016-03-23 成都市白蚁防治研究所 Method for marking termites by staining
CN105409888B (en) * 2015-10-30 2017-12-05 成都市白蚁防治研究所 A kind of method of dye marker termite
CN106320000A (en) * 2016-08-18 2017-01-11 福建省华普新材料有限公司 Fluorescent dye for spinning
CN114441271A (en) * 2021-12-27 2022-05-06 桂林优利特医疗电子有限公司 Preparation of novel dyeing liquid and dyeing method
CN114441271B (en) * 2021-12-27 2023-06-27 桂林优利特医疗电子有限公司 Novel dyeing liquid preparation and dyeing method

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Application publication date: 20110615