CN102091174B - Medicament for treating psoriasis and preparation method thereof - Google Patents
Medicament for treating psoriasis and preparation method thereof Download PDFInfo
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- CN102091174B CN102091174B CN2011100263662A CN201110026366A CN102091174B CN 102091174 B CN102091174 B CN 102091174B CN 2011100263662 A CN2011100263662 A CN 2011100263662A CN 201110026366 A CN201110026366 A CN 201110026366A CN 102091174 B CN102091174 B CN 102091174B
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- 239000003814 drug Substances 0.000 title claims abstract description 42
- 201000004681 Psoriasis Diseases 0.000 title abstract description 11
- 238000002360 preparation method Methods 0.000 title abstract description 4
- 241000628997 Flos Species 0.000 claims description 22
- 238000000034 method Methods 0.000 claims description 17
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 11
- 239000000843 powder Substances 0.000 claims description 11
- 229940079593 drug Drugs 0.000 claims description 9
- 239000006187 pill Substances 0.000 claims description 9
- 238000004519 manufacturing process Methods 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- 230000002682 anti-psoriatic effect Effects 0.000 claims description 7
- 229940030999 antipsoriatics Drugs 0.000 claims description 7
- 230000001954 sterilising effect Effects 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 16
- 208000024891 symptom Diseases 0.000 abstract description 6
- 239000002994 raw material Substances 0.000 abstract description 5
- 230000006378 damage Effects 0.000 abstract description 3
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 241000301400 Trogopterus Species 0.000 abstract 1
- 210000003608 fece Anatomy 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 206010015150 Erythema Diseases 0.000 description 12
- 206010037888 Rash pustular Diseases 0.000 description 12
- 231100000321 erythema Toxicity 0.000 description 12
- 208000029561 pustule Diseases 0.000 description 12
- 206010040844 Skin exfoliation Diseases 0.000 description 6
- 230000035618 desquamation Effects 0.000 description 6
- 238000011084 recovery Methods 0.000 description 6
- 208000003251 Pruritus Diseases 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000036039 immunity Effects 0.000 description 4
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- 241000245240 Lonicera Species 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 230000001185 psoriatic effect Effects 0.000 description 3
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- 231100000444 skin lesion Toxicity 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 208000001840 Dandruff Diseases 0.000 description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- 239000002729 catgut Substances 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 241001070941 Castanea Species 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 206010018092 Generalised oedema Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 206010037575 Pustular psoriasis Diseases 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 206010048222 Xerosis Diseases 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- CKMXBZGNNVIXHC-UHFFFAOYSA-L ammonium magnesium phosphate hexahydrate Chemical compound [NH4+].O.O.O.O.O.O.[Mg+2].[O-]P([O-])([O-])=O CKMXBZGNNVIXHC-UHFFFAOYSA-L 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 208000024783 anasarca Diseases 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
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- 230000000740 bleeding effect Effects 0.000 description 1
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- 230000002175 menstrual effect Effects 0.000 description 1
- 206010034754 petechiae Diseases 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 208000014268 psoriasis 15 Diseases 0.000 description 1
- 208000014236 psoriasis 3 Diseases 0.000 description 1
- 208000014271 psoriasis 5 Diseases 0.000 description 1
- 208000014341 psoriasis 7 Diseases 0.000 description 1
- 208000014267 psoriasis 8 Diseases 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 229910052567 struvite Inorganic materials 0.000 description 1
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Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a medicament, in particular to a medicament which is prepared from multiple traditional Chinese medicines serving as raw materials and is used for treating psoriasis. The invention also relates to a preparation method of the medicament. The medicament mainly solves the problems of long treatment period, serious side effect, medicament resistance, easy relapse, cure of symptoms but not root causes and undesirable curative effect of the conventional medicament for treating the psoriasis in clinic. The medicament for treating the psoriasis comprises the following raw material medicaments in part by weight: 50 to 70 parts of honeysuckle, 50 to 70 parts of Indian buead, 20 to 50 parts of raw rehmannia root, 6 to 12 parts of trogopterus dung, 6 to 9 parts of safflower and 30 to 80 parts of root of red-rooted salvia. The medicament is prepared by a simple preparation method, free from side effects, can cure the patient in a short period without bringing extra body damage to the patient, avoids arousing medicament resistance, and has remarkable curative effect and high cure rate.
Description
Technical field
The present invention relates to a kind of medicine, particularly a kind of is the antipsoriatics thing of feedstock production with the plurality of Chinese, the invention still further relates to the method for preparing of this medicine.
Background technology
Psoriasis is a kind of common chronic, recurrent, and struvite dermatosis, what wherein sickness rate was higher is homeliness type psoriasis and pustular psoriasis.Treat psoriasis at present clinically and mainly adopt operation catgut embedding for treatment, Western medicine or Chinese medicine, the cycle of operation catgut embedding for treatment is long, sunkens cord for a long time patient body is caused injury to a certain degree, and side effect is big; The western medicine psoriasis mainly is some hormone medicines, takes for a long time to be prone to develop immunity to drugs, and is prone to recurrence; Also have some to be used to treat psoriasic Chinese medicine at present, but cure the symptoms, not the disease mostly, treatment cycle is long, and curative effect is not remarkable.
Summary of the invention
The present invention is primarily aimed at that present clinical treatment psoriasis exists that treatment cycle is long, side effect big, is prone to develop immunity to drugs, is prone to recur, cures the symptoms, not the disease, the inapparent problem of curative effect, and provide a kind of treatment cycle to lack, have no side effect, do not have Drug resistance, do not recur, treating both the principal and secondary aspects of a disease, antipsoriatics thing evident in efficacy.
The invention still further relates to the method for preparing of this medicine.
Antipsoriatics thing of the present invention is to be crude drug with following parts of medicines by weight:
Flos Lonicerae 50～70, Poria 50～70, Radix Rehmanniae 20～50, Oletum Trogopterori 6～12, Flos Carthami 6～9, Radix Salviae Miltiorrhizae 30～80.
Medicine of the present invention can be processed any dosage form on the pharmaceutics, and like decoction, tablet, pill, powder, capsule etc., wherein the preferred dosage form of the present invention is a honey pill agent.
The method for preparing of honeyed pill of the present invention is: Flos Lonicerae, Poria, Radix Rehmanniae, Oletum Trogopterori, Flos Carthami and the Radix Salviae Miltiorrhizae mix homogeneously of getting above-mentioned parts by weight earlier; Be ground into 80～120 purpose fine powders; The Mel that in fine powder, adds 1～1.5 times of amount is then mixed well, and processes honeyed pill according to the manufacture method sterilization of routine by metering.
In the prescription of the present invention, Flos Lonicerae sweet in the mouth cold in nature, have antibacterial, antiviral, antiinflammatory, analgesic, regulate function such as immunity; Poria property slightly sweet flavor is flat, has eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effects such as mind tranquilizing and the heart calming; The Radix Rehmanniae sweet-bitter flavor is cold in nature, has YIN nourishing and the production of body fluid promoting, effects such as clearing away heat and cooling blood; The Oletum Trogopterori sweet-bitter flavor is warm in nature, has promoting blood circulation and stopping pain, effects such as removing stasis to stop bleeding; The Flos Carthami acrid in the mouth is warm in nature, has effects such as promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; The little hot cold nature of Radix Salviae Miltiorrhizae bitter in the mouth; Has blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, effects such as removing heat from blood detumescence.
For showing the present invention to the psoriasis treatment effect, the present invention has carried out clinical observation on the therapeutic effect to 200 routine psoriatics, and the result shows: effective percentage is 95%, and cure rate is 93%, and is specific as follows:
Homeliness type psoriatic 100 examples, symptom: occur patch or speckle on the skin, there are thicker silvery white phosphorus bits on the surface; Out-of-shape, what have has map or an island appearance outward appearance, and the skin lesion that has is less; Be the Caulis et folium pavettae hongkongensis outward appearance, the squama layer constantly comes off, and wipes scurf gently off and can see the red film of very thin one deck; Strike off red film and can see slight petechia, itch all over; Taking medicine of the present invention after 20～50 days, no longer itches in the affected part, and the silvery white phosphorus bits of skin surface come off, and skin is little red, continues to take medicine of the present invention and fully recovers after 20～40 days.
Pustule type psoriatic 100 examples: symptom: at the both hands palm and toes portion the symmetry erythema is arranged, occur the pustule that syringe needle arrives chestnut Mi Daxiao greatly on the erythema, approximately 1-2 is dry voluntarily after week, has new pustule to occur behind the desquamation again, repeatedly outbreak; Took medicine of the present invention 20～50 days, pustule is dry, and the erythema area reduces, and color shoals, and continues to take medicine of the present invention 20～40 days, and erythema disappears, recovery from illness.
Model case is following:
Patient Lee: the man, 50 years old, suffered from the homeliness type psoriasis 8 years, speckle shape erythema and squama are arranged on one's body; Desquamation decortication back skin damage is serious, and anasarca is very itched and is impatient at, neck, oxter, inguinal lymph nodes enlargement; Constipation, loss of appetite four months can not be controlled after injecting 5 bottles of import methotrexates and multiple therapy, and the state of an illness progressively increases the weight of; Work, neither can normally the carrying out of life were taken medicine of the present invention 30 days, and effect is remarkable, and skin lesion heals gradually; Scratchiness disappears, and continues to take 20 days, and it is normal that skin recovers, and consolidates and takes recovery from illness after 10 days.
Patient Wang, the woman 45 years old, suffered from the homeliness type psoriasis 15 years; Shirtfront back is all surrounded one by squama, xerosis cutis, desquamation, pruritus, and taking Western medicine all is to take effect for the first time; Drug withdrawal is recurrence just, takes 20 days scurfs of medicine of the present invention and begins to come off, and the skin lesion area dwindles gradually; After 40 days, clinical symptoms is eliminated basically, consolidates and takes recovery from illness after 10 days.
Patient Lee, the man, 39 years old, suffered from the homeliness type psoriasis 7 years, psoriasis is long more many more on one's body for many years; Join together, the whole body desquamation, painful hard to bear, take medicine of the present invention after 25 days; The state of an illness is clearly better, and about 40 days, the erythra of bulk begins to disappear on one's body, only surplus a little pigmentation spots; The affected part healing is continued to strengthen and was taken medicine 20 days, transference cure, patient's recovery from illness.
Patient Zhang, the woman, 25 years old, suffered from the pustule type psoriasis 3 years, earlier arm occur point-like erythema, after develop into pustule; Approximately 1-2 is dry voluntarily after week, has the new pustule that differs in size to occur behind the desquamation again, acutely scratches where it itches, and has difficulty in going to sleep every spring and autumn and winter; State of an illness rapid deterioration was taken medicine of the present invention 30 days, and pustule is dry, and the erythema area reduces; Color shoals, and continues to take medicine of the present invention 40 days, and erythema disappears, patient's recovery from illness.
Patient Wang, man, 55 years old; Suffered from the pustule type psoriasis 5 years, the cause of disease is to feel the trick discomfort after drenching with rain owing to suffering from cold, and in trick, works the symmetry erythema that differs in size subsequently; The big pimple of syringe needle appears on the erythema; Pustule is dry voluntarily after about 10 days, has new pustule to occur behind the desquamation again, repeatedly outbreak; Took medicine of the present invention 35 days, pustule is dry, and the erythema area reduces, and color shoals, and continues to take medicine of the present invention 30 days, and erythema disappears, patient's recovery from illness.
Process for preparing medicine of the present invention is simple, have no side effect, patient's life cycle is short and can not bring extra actual bodily harm to the patient, can not develop immunity to drugs and evident in efficacy, cure rate is high.
The specific embodiment
Embodiment 1
Take by weighing raw material by following proportioning:
50 kilograms of Flos Loniceraes, 50 kilograms in Poria, 20 kilograms of Radix Rehmanniae, 6 kilograms of Oletum Trogopteroris, 6 kilograms on Flos Carthami, 30 kilograms of Radix Salviae Miltiorrhizaes.
Concrete method for preparing: Flos Lonicerae, Poria, Radix Rehmanniae, Oletum Trogopterori, Flos Carthami and the Radix Salviae Miltiorrhizae mix homogeneously of getting above-mentioned weight; Be ground into 80 purpose fine powders; In fine powder, add 162 kilograms of Mel then and mix well, process honeyed pill by metering according to the manufacture method sterilization of routine.
Embodiment 2
Take by weighing raw material by following proportioning:
60 kilograms of Flos Loniceraes, 60 kilograms in Poria, 35 kilograms of Radix Rehmanniae, 9 kilograms of Oletum Trogopteroris, 7 kilograms on Flos Carthami, 50 kilograms of Radix Salviae Miltiorrhizaes.
Concrete method for preparing: Flos Lonicerae, Poria, Radix Rehmanniae, Oletum Trogopterori, Flos Carthami and the Radix Salviae Miltiorrhizae mix homogeneously of getting above-mentioned weight; Be ground into 100 purpose fine powders; In fine powder, add 265 kilograms of Mel then and mix well, process honeyed pill by metering according to the manufacture method sterilization of routine.
Embodiment 3
Take by weighing raw material by following proportioning:
70 kilograms of Flos Loniceraes, 70 kilograms in Poria, 50 kilograms of Radix Rehmanniae, 12 kilograms of Oletum Trogopteroris, 9 kilograms on Flos Carthami, 80 kilograms of Radix Salviae Miltiorrhizaes.
Concrete method for preparing: Flos Lonicerae, Poria, Radix Rehmanniae, Oletum Trogopterori, Flos Carthami and the Radix Salviae Miltiorrhizae mix homogeneously of getting above-mentioned weight; Be ground into 120 purpose fine powders; In fine powder, add 430 kilograms of Mel then and mix well, process honeyed pill by metering according to the manufacture method sterilization of routine.
Claims (3)
1. antipsoriatics thing is characterized in that with following parts of medicines by weight be crude drug:
Flos Lonicerae 50～70, Poria 50～70, Radix Rehmanniae 20～50, Oletum Trogopterori 6～12, Flos Carthami 6～9, Radix Salviae Miltiorrhizae 30～80.
2. antipsoriatics thing according to claim 1 is characterized in that said medicine is processed honeyed pill.
3. the method for preparing of the described antipsoriatics thing of claim 2; It is characterized in that getting earlier Flos Lonicerae, Poria, Radix Rehmanniae, Oletum Trogopterori, Flos Carthami and the Radix Salviae Miltiorrhizae mix homogeneously of above-mentioned parts by weight; Be ground into 80～120 purpose fine powders; The Mel that in fine powder, adds 1～1.5 times of amount is then mixed well, and processes honeyed pill according to the manufacture method sterilization of routine by metering.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100263662A CN102091174B (en) | 2011-01-21 | 2011-01-21 | Medicament for treating psoriasis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100263662A CN102091174B (en) | 2011-01-21 | 2011-01-21 | Medicament for treating psoriasis and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102091174A CN102091174A (en) | 2011-06-15 |
| CN102091174B true CN102091174B (en) | 2012-01-25 |
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| CN2011100263662A Expired - Fee Related CN102091174B (en) | 2011-01-21 | 2011-01-21 | Medicament for treating psoriasis and preparation method thereof |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075164A (en) * | 2016-08-16 | 2016-11-09 | 黄琴 | For antipsoriatics thing |
| CN107854576A (en) * | 2017-11-27 | 2018-03-30 | 江苏辉腾环保科技有限公司 | A kind of antipsoriatics thing component and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101099817A (en) * | 2007-06-20 | 2008-01-09 | 济南新境界企业管理咨询有限公司 | Internal-applied traditional Chinese medicine composition for treating psoriasis |
| CN101129716A (en) * | 2007-08-29 | 2008-02-27 | 泰维昌 | Orally taken Chinese medicine for treating psoriasis |
| CN101698045A (en) * | 2009-11-23 | 2010-04-28 | 赵霞 | Traditional Chinese medicine powder for treating psoriasis and preparation method |
-
2011
- 2011-01-21 CN CN2011100263662A patent/CN102091174B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101099817A (en) * | 2007-06-20 | 2008-01-09 | 济南新境界企业管理咨询有限公司 | Internal-applied traditional Chinese medicine composition for treating psoriasis |
| CN101129716A (en) * | 2007-08-29 | 2008-02-27 | 泰维昌 | Orally taken Chinese medicine for treating psoriasis |
| CN101698045A (en) * | 2009-11-23 | 2010-04-28 | 赵霞 | Traditional Chinese medicine powder for treating psoriasis and preparation method |
Non-Patent Citations (3)
| Title |
|---|
| 刘巧.中医皮肤病的治疗.《中国中西医结合皮肤性病学杂志》.2009,第08卷(第02期),122-124. * |
| 吴淞.谈谈皮肤病的辨治.《江苏中医》.2002,第22卷(第12期),1-2. * |
| 宋兆友.常用皮肤病中药外用制剂介绍.《皮肤病与性病》.2006,第28卷(第01期),23-25. * |
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| CN102091174A (en) | 2011-06-15 |
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