CN102087172B - Quantitative biological sampling flocking swab - Google Patents
Quantitative biological sampling flocking swab Download PDFInfo
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- CN102087172B CN102087172B CN201010604583.0A CN201010604583A CN102087172B CN 102087172 B CN102087172 B CN 102087172B CN 201010604583 A CN201010604583 A CN 201010604583A CN 102087172 B CN102087172 B CN 102087172B
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- swab
- annular support
- cashmere
- flocking
- planted layer
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Abstract
The present invention is to provide a kind of quantitative biological sampling flocking swab, and including swab handle and swab head, swab head is to cover the cashmere-planted layer in swab handle end, and the end of the one or both ends of swab handle is set to annular support structure, and cashmere-planted layer covers on the surface of annular support；Realize the definite value that liquid volume is 10～200 μ l scopes that sampling quantity is big, can control Absorption quantity, and swab head difficult drop-off, easy to use and safety good.
Description
Technical field
The present invention relates to a kind of biological experiment equipment, especially relate to a kind of quantitative biological sampling flocking swab.
Background technology
In field of biology, can the collection of biological specimen (including biological cell and biomolecule) and transmission be the most important condition that carry out effective lab testing, in numerous biological specimen collections and Transfer Technology, swab sampling is a kind of the most frequently used and Sampling techniques the most easily, and wherein sampling swab is the sampling equipment of most critical.Can complete reliably gathered biological specimen by sampling sites and be delivered to safely the experimentation of laboratory around sampling swab composition sampling transmission system equipment.
At present, the structure of conventional biological sampling swab includes swab handle and swab head.Swab handle is a bar-shaped cylinder, tool certain degree of hardness resilient material make, and one end is handgrip part, and one or both ends all can be as the position making swab head.Swab head be fixed on swab handle one or both ends can the part of active adsorption biological specimen, be divided into winding, flocking and foaming three class.Integrated comparative, existing three class biological sampling swabs have following defects that (1) winding, flocking or foaming swab head are all distributed in swab handle one end along swab handle major axis, the half of the not enough whole swab head of effective contact portion of swab head and sampling sites when actually used, tending not to effectively gather liquid sample, the active adsorption amount causing swab is not enough；(2) the swab head by being wound around or expanded material wraps up is combined insecure with swab handle, is susceptible to swab head and comes off；(3) existing three class swabs can only saturated sampling and do not possess the performance of quantitative collection biological specimen；The cylinder top end of the swab handle of (4) three class swabs likely damages sampling sites.
Summary of the invention
Present invention aim to address traditional biological sampling swab can not quantitative sampling, sample adsorbance low, and solve swab head problem easy to fall off and unsafe.
To achieve these goals, the present invention provides a kind of quantitative biological sampling flocking swab, including swab handle and swab head, swab head is to cover the cashmere-planted layer in swab handle end, it is characterized in that: the end of the one or both ends of swab handle is set to annular support structure, cashmere-planted layer covers on the surface of annular support.
Annular support annular diameters is 1.25～10 mm, and annular support cylinder cross-sectional diameter is 0.2～3 mm.
Annular support is 2.5～296 mm as effective flocking area of flocked substrates2。
Annular support is arranged to the polygonal annular on more than annular, oval ring, three limit annulars or at least three limits, and annular support cylinder cross section is arranged to circle, ellipse or polygon.
The fibre length of cashmere-planted layer is 0.2～3.0 mm, and the fibre number of cashmere-planted layer is 0.33～7.0 dtex, and the fibre density of cashmere-planted layer is 1.5～350 μ g/mm2。
The material of swab handle is polypropylene plastics, vinyon, poly terephthalic acid class plastics, polystyrene plastics or engineering plastics.
Cashmere-planted layer uses natural fiber, or chemical fibre, or the composite fibre of the two covers on the surface of annular support.
Cashmere-planted layer uses nylon fiber to cover on the surface of annular support.
It is provided with the fracture being easy to pinpoint the swab handle that fractures on swab handle, or can not set fracture on the swab handle that fractures of arbitrfary point with what modified polystyrene plastics made.
The annular support annular diameters of quantitative biological sampling flocking swab and annular support cylinder cross-sectional diameter are to determine effective flocking area and then control gather sample volume and realize the principal element of quantitative collection sample.Additionally, swab can the volume of collecting sample also be affected by fibre length, fibre number and the fibre density of cashmere-planted layer.Compared with being columned tradition swab head with common end, with the long-pending increase of flocked surface of the base material that annular support is obtained by base material, namely increase efficiently sampling amount by the effective flocking area of increase.The present invention is by controlling annular support annular diameters and annular support cylinder cross-sectional diameter, control to implement the surface area of flocked substrates, the regulation fibre number of cashmere-planted layer, fibre length and the change of fibre density, finally make swab head possess quantitative sampling function further.The swab made according to the principle of the present invention, absorb water under 25 DEG C of environmental conditions gravimetry (H2O@25 DEG C) definite value that controlled formulation amount sampling volume is 10～200 μ l scopes that detects.
Owing to the efficiently sampling position of the flocking sampling swab of present invention acquisition concentrates on swab handle end, can completely attach to being sampled position when implementing sampling, it is ensured that fully collecting sample；Owing to using annular support structure, no longer use the simple columnar design following swab handle end for many years, make swab head both difficult drop-offs also effectively eliminate the probability that sampling swab causes sampling sites to injure.
The quantitative biological sampling flocking swab that the present invention obtains has the advantage that
(1) can be according to the quantitative biological sampling flocking swab needing the different sampling quantity of selection of collecting sample.
(2) the swab head effective site of quantitative biological sampling flocking swab completely attaches to sampling sites, it is ensured that sampling quantity maximizes.
(3) quantitative biological sampling flocking swab can quantitative collection sample, contribute to realizing after experiment detection directly result of calculation.
(4) quantitative biological sampling flocking swab efficiently solve swab head loosen and the problem that comes off.
(5) quantitative biological sampling flocking swab overcomes the problem that sampling sites (such as human body) is damaged by swab completely.
Accompanying drawing explanation
Fig. 1 is the structure sectional view of the embodiment of the present invention one.
Fig. 2 is the annular support cylinder cross sectional representation of the embodiment of the present invention one.
Fig. 3 is the sectional view of the annular support of the embodiment of the present invention one.
Fig. 4 is the swab structure sectional view that prior art produces.
Wherein: 1-swab handle, 2-cashmere-planted layer, 3-fracture, 4-annular support.
Detailed description of the invention
The preferred embodiments of the present invention are described in detail below according to accompanying drawing.
Embodiment one as shown in Figure 1, Figure 2, shown in Fig. 3, the present embodiment provides a kind of quantitative biological sampling flocking swab, including swab handle 1 and swab head, the end of one end of swab handle 1 is arranged to annular support 4, or the end at swab handle 1 two ends can also be arranged respectively to annular support 4, the ring-type annular that is arranged to of the annular support 4 of the present embodiment, or the polygonal annular on more than oval ring, three limit annulars or at least three limits can also be arranged to；Annular support 4 cylinder cross section is arranged to circle, or can also be arranged to ellipse or polygon.
Annular support 4 annular diameters of the present embodiment may be provided between 1.25～10 mm scopes, and the present embodiment is set to 3.91 mm；Annular support 4 cylinder cross-sectional diameter may be provided between 0.2～3 mm scopes, and the present embodiment is set to 1.19 mm；Swab handle 1 and annular support 4 can use vinyon, poly terephthalic acid class plastics or engineering plastics, the present embodiment uses polypropylene plastic material to make, and the fracture 3 being easy to pinpoint the swab handle 1 that fractures it is provided with as required in swab handle 1 part, use with the transmission after facilitating sampling；Or the swab handle 1 of polystyrene material manufacture of modification can also be used to realize fractureing in arbitrfary point.
With annular support 4 as base material, making cashmere-planted layer 2 cover on the surface of annular support 4 base material, effective cashmere-planted layer area of annular support 4 substrate surface may be provided at 2.5～296 mm2Between scope, the present embodiment is 46 mm2；The fibre length of cashmere-planted layer 2 may be provided between 0.2～3.0 mm scopes, and the present embodiment is 0.6 mm；The fibre number of cashmere-planted layer 2 may be provided between 0.33～7.0 dtex scopes, and the present embodiment is 1.5 dtex；The fibre density of cashmere-planted layer 2 may be provided at 1.5～350 μ g/mm2Between scope, the present embodiment is 17 μ g/mm2；The material that swab head cashmere-planted layer 2 relates to is natural fiber, or chemical fibre, or the composite fibre of the two, and the present embodiment is nylon fiber.
Compared with tradition swab shown in Fig. 4, the advantage of the present embodiment shows as that sampling quantity is big, the liquid volume that can determine Absorption quantity is 55 μ l(H2O@25 DEG C), swab head difficult drop-off, easy to use and safety good.
Embodiment two, annular support 4 annular diameters 5 mm, annular support 4 cylinder cross-sectional diameter 1.5 mm, base material effective flocking area of annular support 4 is 74 mm2 , nylon fiber length 1.5 mm, fibre number 6.67 dtex, the fibre density 328 μ g/mm of cashmere-planted layer 22 , adsorptive liquid volume 110 μ l(H2O@25 DEG C), remaining is with embodiment one.
Embodiment three, annular support 4 annular diameters 1.5 mm, annular support 4 cylinder cross-sectional diameter 0.5 mm, base material effective flocking area of annular support 4 is 7.39 mm2 , nylon fiber length 1.0 mm, fibre number 1.5 dtex, the fibre density 109 μ g/mm of cashmere-planted layer 22, adsorptive liquid volume 20 μ l(H2O@25 DEG C), remaining is with embodiment one.
Claims (7)
1. quantitative biological sampling flocking swab, including swab handle (1) and swab head, swab head is to cover the cashmere-planted layer in swab handle end, it is characterized in that: the end of the one or both ends of swab handle (1) is set to annular support (4) structure, cashmere-planted layer (2) covers the surface in annular support (4)；
Annular support (4) annular diameters is 1.25～10 mm, and annular support (4) cylinder cross-sectional diameter is 0.2～3 mm；
Annular support (4) is 2.5～296 mm as effective flocking area of flocked substrates2；
The fibre length of cashmere-planted layer (2) is 0.2～3.0 mm, and the fibre number of cashmere-planted layer (2) is 0.33～7.0
Dtex, the fibre density of cashmere-planted layer (2) is 1.5～350 μ g/mm2；
By regulation annular support internal diameter, annular support cylinder cross-sectional diameter, effective flocking area, the fibre number of cashmere-planted layer, the fibre length of cashmere-planted layer, the fibre density of cashmere-planted layer so that swab head quantitative sampling volume is a definite value of 10～200ul scopes.
Quantitative biological sampling flocking swab the most according to claim 1, it is characterized in that: annular support (4) is arranged to annular, oval ring, three limit annular or the polygonal annular more than three limits, and annular support (4) cylinder cross section is arranged to circle, ellipse or polygon.
Quantitative biological sampling flocking swab the most according to claim 1, it is characterised in that: the material of swab handle (1) is polypropylene plastics, vinyon, poly terephthalic acid class plastics or polystyrene plastics.
Quantitative biological sampling flocking swab the most according to claim 1, it is characterised in that: cashmere-planted layer (2) uses natural fiber, or chemical fibre, or the composite fibre of the two covers the surface in annular support (4).
5. according to the quantitative biological sampling flocking swab described in claim 1 or 4, it is characterised in that: cashmere-planted layer (2) uses nylon fiber to cover the surface in annular support (4).
Quantitative biological sampling flocking swab the most according to claim 1, it is characterized in that: be provided with on swab handle (1) and be easy to fixed point and fracture the fracture (3) of swab handle (1), or can not set fracture (3) on the swab handle (1) that fractures of arbitrfary point with what modified polystyrene plastics made.
Quantitative biological sampling flocking swab the most according to claim 1, it is characterised in that: the material of swab handle (1) is engineering plastics.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010604583.0A CN102087172B (en) | 2010-12-24 | 2010-12-24 | Quantitative biological sampling flocking swab |
| PCT/CN2011/000203 WO2012083572A1 (en) | 2010-12-24 | 2011-02-09 | Flocking swab for biological sampling quantitatively and method for making the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010604583.0A CN102087172B (en) | 2010-12-24 | 2010-12-24 | Quantitative biological sampling flocking swab |
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| CN102087172A CN102087172A (en) | 2011-06-08 |
| CN102087172B true CN102087172B (en) | 2016-09-07 |
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| CN201010604583.0A Active CN102087172B (en) | 2010-12-24 | 2010-12-24 | Quantitative biological sampling flocking swab |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| FI20155110L (en) * | 2015-02-19 | 2016-08-20 | Thermo Fisher Scientific Oy | Sampler and combination of sampler and sample container |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2460050Y (en) * | 2001-01-18 | 2001-11-21 | 江苏苏云医疗器材有限公司 | Medical sampling swab |
| CN201085636Y (en) * | 2007-09-25 | 2008-07-16 | 王学礼 | Disposal bone shaped neck of uterus flighter |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1325287A (en) * | 1998-07-23 | 2001-12-05 | 奥乐斯堪/崔龙合资企业公司 | Device and method for obtaining a transepithelial sample of a body surface using a non-scratch technique |
| CN101243982B (en) * | 2008-03-21 | 2010-08-18 | 周星 | Uterine cervix brush |
| CN201993241U (en) * | 2010-12-24 | 2011-09-28 | 江苏世泰实验器材有限公司 | Quantitative biological sampling flocked swab |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2460050Y (en) * | 2001-01-18 | 2001-11-21 | 江苏苏云医疗器材有限公司 | Medical sampling swab |
| CN201085636Y (en) * | 2007-09-25 | 2008-07-16 | 王学礼 | Disposal bone shaped neck of uterus flighter |
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Effective date of registration: 20240102 Address after: 226100 No.48, Xinxiu Road, Haimen street, Haimen District, Nantong City, Jiangsu Province Patentee after: Jiangsu yingwotai Biotechnology Co.,Ltd. Address before: No. 48 Xinxiu Road, Haimen City, Nantong City, Jiangsu Province, 226100 Patentee before: CITOTEST LABWARE MANUFACTURING Co.,Ltd. |
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