CN101978989A - Chinese medicament for treating diabetic diarrhea - Google Patents
Chinese medicament for treating diabetic diarrhea Download PDFInfo
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- CN101978989A CN101978989A CN2010105282542A CN201010528254A CN101978989A CN 101978989 A CN101978989 A CN 101978989A CN 2010105282542 A CN2010105282542 A CN 2010105282542A CN 201010528254 A CN201010528254 A CN 201010528254A CN 101978989 A CN101978989 A CN 101978989A
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- 206010012735 Diarrhoea Diseases 0.000 title claims abstract description 23
- 239000003814 drug Substances 0.000 title claims abstract description 22
- 206010012601 diabetes mellitus Diseases 0.000 title claims abstract description 14
- 241000222336 Ganoderma Species 0.000 claims abstract description 9
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 10
- 241000180649 Panax notoginseng Species 0.000 claims description 10
- 210000000582 semen Anatomy 0.000 claims description 10
- 230000000694 effects Effects 0.000 abstract description 15
- 239000008280 blood Substances 0.000 abstract description 11
- 210000004369 blood Anatomy 0.000 abstract description 11
- 239000002994 raw material Substances 0.000 abstract description 2
- MFYSUUPKMDJYPF-UHFFFAOYSA-N 2-[(4-methyl-2-nitrophenyl)diazenyl]-3-oxo-n-phenylbutanamide Chemical compound C=1C=CC=CC=1NC(=O)C(C(=O)C)N=NC1=CC=C(C)C=C1[N+]([O-])=O MFYSUUPKMDJYPF-UHFFFAOYSA-N 0.000 abstract 1
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 244000270834 Myristica fragrans Species 0.000 abstract 1
- 235000009421 Myristica fragrans Nutrition 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 235000003181 Panax pseudoginseng Nutrition 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 241000219784 Sophora Species 0.000 abstract 1
- 241001534869 Terminalia Species 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 239000001702 nutmeg Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 description 15
- 239000000843 powder Substances 0.000 description 13
- 238000000034 method Methods 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- 241000498779 Myristica Species 0.000 description 6
- 241000001522 Terminalia chebula Species 0.000 description 6
- 230000001737 promoting effect Effects 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 4
- 230000000968 intestinal effect Effects 0.000 description 4
- 241000207961 Sesamum Species 0.000 description 3
- 235000003434 Sesamum indicum Nutrition 0.000 description 3
- 239000003212 astringent agent Substances 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- AXONCVPTTFHNOI-UHFFFAOYSA-N kairine Chemical compound C1=CC(O)=C2N(C)CCCC2=C1 AXONCVPTTFHNOI-UHFFFAOYSA-N 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 2
- 230000036770 blood supply Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 206010062198 microangiopathy Diseases 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 201000001119 neuropathy Diseases 0.000 description 2
- 230000007823 neuropathy Effects 0.000 description 2
- 208000033808 peripheral neuropathy Diseases 0.000 description 2
- 238000007560 sedimentation technique Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 238000003809 water extraction Methods 0.000 description 2
- 230000002411 adverse Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 229940127003 anti-diabetic drug Drugs 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 239000003472 antidiabetic agent Substances 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 208000033065 inborn errors of immunity Diseases 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 208000028529 primary immunodeficiency disease Diseases 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
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Abstract
The invention discloses a Chinese medicament for treating diabetic diarrhea, and belongs to the field of Chinese medicaments for treating diabetes. The Chinese medicament has good effect and quick response. The Chinese medicament is prepared from raw materials such as light-yellow sophora root, terminalia fruit, glossy ganoderma, root of pseudo-ginseng, nutmeg, Chinese angelica, root of red rooted salvia and the like. The Chinese medicament has the effects of supporting right, banking up root, replenishing qi, nourishing blood, activating blood, dissolving stasis, astringing intestines and stopping diarrhea, and has the advantages of remarkable effect, extract curative effect and quick response.
Description
Technical field
The invention belongs to the field of Chinese medicines of treatment diabetes.
Background technology
Diabetic diarrhea is due to the diabetes complicated intestinal microangiopathies and neuropathy.Much in diabetics.Because antibiotic is invalid to this, this disease is refractory very.There is the deficiency of two aspects in the present Chinese medicine that is used for the treatment of diabetic diarrhea: the one, and effect is obvious inadequately, and the 2nd, it is slower to take effect, so that large quantities of these patients suffer from diarrhoea incessantly all the year round, very misery.
At above problem, the invention provides a kind of Chinese medicine for the treatment of diabetic diarrhea, effect was obvious inadequately during it can solve and treat in the past, the slower problem that takes effect, effective, instant effect, it is remarkable to have effect, and drug effect is definite, the advantage of quick result.
Summary of the invention
The present invention is achieved through the following technical solutions:
1, a kind of Chinese medicine for the treatment of diabetic diarrhea adopts the raw material of Chinese medicine preparation, and filling a prescription is (by weight):
Radix Sophorae Flavescentis 5---18 parts of 15 parts of Fructus Chebulaes 5---15 portions of Ganodermas 6---
Radix Notoginseng 3---18 parts of 9 parts of Semen Myristicaes 5---15 parts of Radix Angelicae Sinensis 6---
Radix Salviae Miltiorrhizae 6---18 parts
The Chinese medicine of this treatment diabetic diarrhea is made by following method:
(1) by above-mentioned weight ratio, Ganoderma is extracted ganoderan with decoction and alcohol sedimentation technique, technological process is as follows: Ganoderma is broken into graininess, cross 40 mesh sieves →, concentrate → mixed, leave standstill 10-12 hour, centrifugal → as to add 75% ethanol with 95% ethanol of 3 times of volumes with 1: 20 hot water (95 ℃) lixiviate → lixiviating solution decompression, precipitate polysaccharide → dry the ganoderan extract fine powder;
(2) by above-mentioned weight ratio, Radix Sophorae Flavescentis, Fructus Chebulae, Semen Myristicae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae are extracted through conventional water extraction process, make extractum extract fine powder;
(3) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, make Chinese medicine granules, capsule, tablet with above-mentioned (1), (2) two kinds of extract fine powders.
The present invention is according to the folk tradition prescription, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling develops meticulously.We think in research, the diabetics hypoimmunity, and the deficiency of YIN is scorching, and blood is sticky, the intestinal blood supply insufficiency, this is the main cause of intestinal generation microangiopathies and neuropathy.Concurrent in addition intractable diarrhea, loose stool is more than all the year round, does not fully recover for a long time, and health degree to the utmost is weak, and the healthy energy scarcity is main pathogenic factor.Sick to middle and late stage, there is the blood stasis phenomenon to some extent.Therefore, set upright, heat clearing away, antidiarrheal, blood circulation promoting and blood stasis dispelling be the main starting point of prescription of the present invention.Ganoderma, Radix Angelicae Sinensis the body resistance strengthening and constitution consolidating in the side, benefiting QI and nourishing blood, enhancing human body immunity power, " removing " effect of immunity makes blood clean, good fluidity, and the intestinal blood supply is full, and this is the key of treatment primary disease; 5 with Radix Salviae Miltiorrhizae, Radix Notoginseng nourshing blood and promoting blood circulation, blood-activating analgetic; Minister is with the Radix Sophorae Flavescentis heat clearing and damp drying; Be aided with Fructus Chebulae's relieving diarrhea with astringents, therapeutic method to keep the adverse QI flowing downwards relieving distension, Semen Myristicae warming middle-JIAO dampness, spleen invigorating circulation of qi promoting, relieving diarrhea with astringents.All medicine compatibilities bring out the best in each other, and play the body resistance strengthening and constitution consolidating altogether, benefiting QI and nourishing blood, and blood circulation promoting and blood stasis dispelling, the merit of relieving diarrhea with astringents, effective, instant effect, it is remarkable to have effect, and drug effect is definite, the advantage of quick result.
The specific embodiment
By following embodiment the present invention is done and to specify:
1, get following prescription (weight is unit by gram):
Radix Sophorae Flavescentis 50 gram Fructus Chebulaes 50 kairine sesames 60 grams
Radix Notoginseng 30 gram Semen Myristicaes 50 gram Radix Angelicae Sinensis 60 grams
Radix Salviae Miltiorrhizae 60 grams
Weight is extracted Ganoderma with decoction and alcohol sedimentation technique in accordance with regulations; With conventional water extraction process Radix Sophorae Flavescentis, Fructus Chebulae, Semen Myristicae, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae are extracted, make extract fine powder 66 grams altogether, Radix Notoginseng is ground into fine powder, mix with said extracted thing fine powder, stir, make fine particle, the capsule of packing into No. 0, make 342 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.
2, get following prescription (weight is unit by gram):
Radix Sophorae Flavescentis 100 gram Fructus Chebulaes 100 kairine sesames 120 grams
Radix Notoginseng 60 gram Semen Myristicaes 100 gram Radix Angelicae Sinensis 120 grams
Radix Salviae Miltiorrhizae 120 grams
By above-mentioned same method, make 685 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.
3, get following prescription (weight is unit by gram):
Radix Sophorae Flavescentis 150 gram Fructus Chebulaes 150 kairine sesames 180 grams
Radix Notoginseng 90 gram Semen Myristicaes 150 gram Radix Angelicae Sinensis 180 grams
Radix Salviae Miltiorrhizae 180 grams
By above-mentioned same method, make 1028 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.28 gram.
4, get following prescription (by weight):
7 parts of 6 portions of Ganodermas of 6 parts of Fructus Chebulaes of Radix Sophorae Flavescentis
7 parts of 6 parts of Radix Angelicae Sinensis of 3 parts of Semen Myristicaes of Radix Notoginseng
7 parts of Radix Salviae Miltiorrhizaes
By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.
5, get following prescription (by weight):
17 parts of 14 portions of Ganodermas of 14 parts of Fructus Chebulaes of Radix Sophorae Flavescentis
17 parts of 14 parts of Radix Angelicae Sinensis of 8 parts of Semen Myristicaes of Radix Notoginseng
17 parts of Radix Salviae Miltiorrhizaes
By above-mentioned same method, make Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.28 gram.
Clinical data:
The present invention is example with the diabetic diarrhea, through 6 routine clinical observations.The selection diabetic diarrhea is a standard: diabetics has a delicate constitution, and asthenia is unable; Rare water sample of defecating during diarrhoea, or diarrhea, not molding, 1 day more than 3 times; Suffer from diarrhoea more than 3 months the antibiotic therapy DeGrain continuously.As above symptom, can make a definite diagnosis.In making a definite diagnosis the object of observation, male's 4 examples, women's 2 examples do not have other serious disease, and the age is 42 years old-74 years old, 61.3 years old mean age.
Efficacy determination:
1, produce effects: body constitution strengthens, on one's body energetically; Diarrhoea stops, the stool molding; Defecate 1~2 day once, defecation is comfortable.
2, effective: weak alleviation, the diarrhoea number of times reduces, and stool half is rare.
3, invalid: the disease no change.
During clinical experiment, except that antidiabetic drug is taken as usual, withdraw other medicines and health nutrient.Take Chinese medicinal capsule of the present invention, observing 3 months is a course of treatment.Instructions of taking: every day 2 times, each 4 capsules, every capsules include Chinese medicine fine powder and extract 0.28 gram, warm water delivery service after meal, symptom promptly has alleviation after 1 month, take 3 months after, symptom is obviously improved.Clinical experiment 6 in, produce effects 3 people, effective 2 people, invalid 1 people, total effective rate 83.3%.
Claims (1)
1. Chinese medicine for the treatment of diabetic diarrhea, it is characterized in that: it is to make with the component of following weight ratio: Radix Sophorae Flavescentis 5---15 parts, the Fructus Chebulae 5---15 parts, Ganoderma 6---18 parts, Radix Notoginseng 3---9 parts, Semen Myristicae 5---15 parts, Radix Angelicae Sinensis 6---18 parts, Radix Salviae Miltiorrhizae 6---18 parts.
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CN2010105282542A CN101978989A (en) | 2010-10-27 | 2010-10-27 | Chinese medicament for treating diabetic diarrhea |
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CN2010105282542A CN101978989A (en) | 2010-10-27 | 2010-10-27 | Chinese medicament for treating diabetic diarrhea |
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CN101978989A true CN101978989A (en) | 2011-02-23 |
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CN2010105282542A Pending CN101978989A (en) | 2010-10-27 | 2010-10-27 | Chinese medicament for treating diabetic diarrhea |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102626456A (en) * | 2012-04-20 | 2012-08-08 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic diarrhea |
CN103006871A (en) * | 2011-09-27 | 2013-04-03 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic diarrhea |
-
2010
- 2010-10-27 CN CN2010105282542A patent/CN101978989A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103006871A (en) * | 2011-09-27 | 2013-04-03 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic diarrhea |
CN102626456A (en) * | 2012-04-20 | 2012-08-08 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic diarrhea |
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PB01 | Publication | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110223 |