CN101964155A - Method for manufacturing anthropotomy cast specimen model - Google Patents
Method for manufacturing anthropotomy cast specimen model Download PDFInfo
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- CN101964155A CN101964155A CN 201010285436 CN201010285436A CN101964155A CN 101964155 A CN101964155 A CN 101964155A CN 201010285436 CN201010285436 CN 201010285436 CN 201010285436 A CN201010285436 A CN 201010285436A CN 101964155 A CN101964155 A CN 101964155A
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- 238000000034 method Methods 0.000 title claims abstract description 25
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 10
- 210000003484 anatomy Anatomy 0.000 claims abstract description 15
- 230000008676 import Effects 0.000 claims abstract description 10
- 238000012545 processing Methods 0.000 claims abstract description 8
- 210000001367 artery Anatomy 0.000 claims description 11
- 210000000621 bronchi Anatomy 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 6
- 230000007547 defect Effects 0.000 claims description 5
- 238000009499 grossing Methods 0.000 claims description 5
- 238000003709 image segmentation Methods 0.000 claims description 5
- 210000001365 lymphatic vessel Anatomy 0.000 claims description 5
- 210000003459 common hepatic duct Anatomy 0.000 claims description 4
- 210000003205 muscle Anatomy 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- 210000003491 skin Anatomy 0.000 claims description 4
- 210000003462 vein Anatomy 0.000 claims description 4
- 238000002591 computed tomography Methods 0.000 claims description 3
- 210000002808 connective tissue Anatomy 0.000 claims description 3
- 239000003086 colorant Substances 0.000 claims description 2
- 210000000944 nerve tissue Anatomy 0.000 claims 1
- 210000000277 pancreatic duct Anatomy 0.000 claims 1
- 238000000547 structure data Methods 0.000 claims 1
- 210000003437 trachea Anatomy 0.000 claims 1
- 238000005266 casting Methods 0.000 abstract description 68
- 239000000463 material Substances 0.000 abstract description 9
- 238000002474 experimental method Methods 0.000 abstract description 3
- 210000004072 lung Anatomy 0.000 description 12
- 238000005516 engineering process Methods 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- 210000000988 bone and bone Anatomy 0.000 description 5
- 238000013461 design Methods 0.000 description 5
- 238000005094 computer simulation Methods 0.000 description 4
- 238000009826 distribution Methods 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 229920002521 macromolecule Polymers 0.000 description 3
- 210000004126 nerve fiber Anatomy 0.000 description 3
- 210000001147 pulmonary artery Anatomy 0.000 description 3
- 210000003492 pulmonary vein Anatomy 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 239000002585 base Substances 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000002639 bone cement Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000011218 segmentation Effects 0.000 description 2
- 208000034189 Sclerosis Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000002406 microsurgery Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
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Abstract
本发明公开了一种人体解剖学铸型标本模型的制作方法，包括步骤：a、采集已有铸型标本或人体标本的原始图像数据；b、分析所述原始图像数据，提取所述原始图像数据中人体内各种管道的结构数据，进行相应图像处理，形成人体铸型标本的三维模型；c、将所述人体铸型标本的三维模型导入快速成型设备中，利用快速成型设备三维打印出所述人体解剖学铸型标本模型。本发明的制作方法不必采用真实的人体标本来制作铸型标本模型，解决了伦理道德问题和寻找制作材料困难的问题。还能准确快速、低成本地制作出不同人体部位的铸型标本模型。大大扩展了人体铸型标本的广泛传播及教学实验的应用。
The invention discloses a method for making a cast specimen model of human anatomy, comprising the steps of: a. collecting original image data of existing cast specimens or human specimens; b. analyzing the original image data and extracting the original image In the data, the structural data of various pipelines in the human body are subjected to corresponding image processing to form a three-dimensional model of the human body casting specimen; c, import the three-dimensional model of the human body casting specimen into the rapid prototyping equipment, and use the rapid prototyping equipment to three-dimensionally print out The human anatomy cast specimen model. The production method of the present invention does not need to use real human body specimens to produce cast specimen models, which solves the problems of ethics and morality and difficulty in finding production materials. It can also produce cast specimen models of different human body parts accurately, quickly and at low cost. It has greatly expanded the wide dissemination of human body cast specimens and the application of teaching experiments.
Description
Technical field
The present invention relates to a kind of method for making of medical model, relate in particular to a kind of method for making that supplies the casting mold sample model of dissection and analysis.
Background technology
Various pipeline is arranged in the animal body, have different functions.Such as structures such as the artery in the human body, vein, lymphatic vessel, digest tube, tracheae, bronchuses, they are interspersed, very complicated, are the objects that must deal carefully with in the operation.Be distribution range and the identical situation of traffic of studying organ interior conduit branch better, people have been developed anatomy casting mold sample technology.Casting mold sample technology is a technical skill of anatomy preparation of specimen, and very high using value is arranged in medical teaching and microsurgery.It is with various pipelines in the human body, make mould such as blood vessel, bronchus, lymphatic vessel, common hepatic duct, ductus pancreaticus etc., the macromolecular compound filling agent is filled in the pipeline with syringe, after treating the filling agent sclerosis in the pipeline, utilize acidproof, the alkaline-resisting characteristic of macromolecular compound again, with acid or alkali other tissue is corroded, thereby make human body casting mold sample.The casting mold sample can reflect comprehensively, truly that organ interior conduit solid constructs form, can help clinician, particularly surgeon to fully understand the anatomical relationship that it is complicated effectively, finally can improve quality of medical care effectively, benefits extensive patients.
But above-mentioned casting mold sample technology also has a lot of limitation, and at first, every making one tool casting mold sample just needs a real human body specimen, and this technology is very big to the demand of sample.Secondly, these casting mold samples are because various human pipelines are staggered, and complex structure can't utilize industrial mould rotating technology commonly used to duplicate this sample, causes manufacturing cost big.In addition,, consider that these casting mold samples can not be as the usefulness of the universal teaching of commodity interchange and colleges and universities based on ethics because each tool casting mold sample is all obtained by the real human body sample.The wide-scale distribution and the application of casting mold sample have more than been limited.
Summary of the invention
The present invention provides a kind of method for making of human anatomy casting mold sample model, utilizes the medical image three-dimensional reconstruction technique, and the various human pipeline's structures of extraction and analysis are produced the casting mold sample model at different human body position fast, at low cost.
The embodiment of the invention provides a kind of method for making of human anatomy casting mold sample model, comprises step:
The raw image data of a, the existing casting mold sample of collection or human body specimen;
B, analyze described raw image data, extract the structured data of various pipelines in the human body, carry out respective image and handle, form the three-dimensional model of human body casting mold sample;
In c, the three-dimensional model importing rapid forming equipment, utilize the rapid forming equipment 3 D-printing to go out described human anatomy casting mold sample model with described human body casting mold sample.
Further, described step a specifically comprises:
By the raw data of the scanning of CT machine or MRI equipment or X-ray production apparatus or 3 D laser scanning equipment collection human body or human body specimen, comprise the Digital Image Data of various pipelines in shape, size, structure, the human body.
Further, described step b specifically comprises:
Raw image data is imported in the three-dimensional reconstruction software, on computers the original human body faultage image data of gathering is carried out image segmentation, eliminate skin, muscle, connective tissue, nerve fiber, extract one or more pipeline configuration images in the human body, and described pipeline configuration in the human body carried out three-dimensional reconstruction, obtain the three-dimensional model of described human body casting mold sample;
Carry out respective image in the three-dimensional model importing image processing software with described human body casting mold sample and handle, comprise surface smoothing, minimizing tri patch, defect repairing, light and shade contrast processing, and design the color and the scaling of various pipeline configurations.
Further, in described step c, the three-dimensional model of the human body casting mold sample that machine Flame Image Process is as calculated crossed imports in the three-dimensional printer, according to the various pipeline kinds differences of described human body casting mold sample, produces the human anatomy casting mold sample model in kind of different colours pipeline configuration.
Various pipeline configuration data are according to the different human body position in the human body described in each step of said method, select to gather the Digital Image Data that comprises one or more pipelines in artery, vein, tracheae, bronchus, lymphatic vessel, common hepatic duct, the ductus pancreaticus structure.
The embodiment of the invention provides a kind of method for making of human anatomy casting mold sample model, needn't adopt real human body specimen to make casting mold sample model, has solved the problem of seeking the manufacturing materials difficulty.Can pass through the 3-D scanning technology to human body specimen or medical science casting mold sample, combining image three-dimensional reconstruction software extracts various pipeline configuration images in the human body, can accurately produce the casting mold sample model at different human body position fast, at low cost.Can certainly duplicate medical science casting mold sample, produce in batches, not be subjected to the influence of human body specimen scarcity of raw material, expand the wide-scale distribution of human body casting mold sample model and the application of education experiment greatly.
Avoided ethics morals problem that corpse is handled simultaneously, mass-produced casting mold sample model, exchanged and the usefulness of the universal teaching of colleges and universities as commodity with existing 3 D-printing material or medical bone cement or medical denture base material.
Description of drawings
Fig. 1 is the method for making process flow diagram of the human anatomy casting mold sample model that provides of the embodiment of the invention.
Embodiment
For making the purpose, technical solutions and advantages of the present invention clearer, the present invention is described in further detail below in conjunction with accompanying drawing.
As shown in Figure 1, the embodiment of the invention provides a kind of method for making of human anatomy casting mold sample model, comprises step:
101, gather the raw image data of existing casting mold sample or human body specimen.
By the raw image data of CT machine or MRI equipment or X-ray production apparatus or 3 D laser scanning equipment collection human body or corpse or medical science casting mold sample, described raw image data comprises the Digital Image Data of various pipelines in shape, size, structure, the human body.
The Digital Image Data of various pipelines is to select to gather according to the different human body position in the described human body, can comprise the Digital Image Data of one or more pipelines in the structures such as artery, vein, tracheae, bronchus, lymphatic vessel, common hepatic duct, ductus pancreaticus.
102, raw image data is imported among the three-dimensional reconstruction software Mimics, extract the structured data of the interior various pipelines of human body in the described three-dimensional model on computers, carry out respective image and handle, form the three-dimensional model of human body casting mold sample.
Concrete, the human body faultage image data of gathering is carried out image segmentation, adjustment, mark different pipelines, such as human body or human body specimen image to collecting, on the computer virtual three-dimensional model, eliminate skin, muscle, nerve fiber, connective tissue etc., extract the image of various pipeline configurations in the human body, and various pipeline configurations are carried out three-dimensional reconstruction, obtain the three-dimensional model of described human body casting mold sample structure; Carrying out respective image among the three-dimensional model importing image processing software 3-Matic with described human body casting mold sample handles, processing procedure comprises surface smoothing, minimizing tri patch, defect repairing, light and shade contrast processing, and design the color and the scaling of various pipeline configurations, make the three-dimensional model of described human body casting mold sample more true to nature.
103, the three-dimensional model with described human body casting mold sample imports in the rapid forming equipment, utilizes the rapid forming equipment 3 D-printing to go out described human anatomy casting mold sample model.
The three-dimensional model of the human body casting mold sample that machine Flame Image Process is as calculated crossed imports among the three-dimensional printer Z-Corp, according to color that designs and scaling, produces human anatomy casting mold sample model in kind.Can go out a plurality of living human body casting mold sample models by batch making by this method, and manufacturing materials obtains easily, cost is low, is convenient to the application of wide-scale distribution and education experiment.
Embodiment one: introduce the process according to lung of casting mold preparation of specimen of lung casting mold sample model.
1, lung's casting mold sample is carried out CT scan or 3 D laser scanning, obtain the faultage image data of lung's casting mold sample.
2, the continuous layer data with lung's casting mold sample imports among the three-dimensional reconstruction software Mimics, function items such as " Threshold Segmentation " that comprehensive three-dimensional reconstruction software carries, " region growing ", faultage image data is carried out image segmentation, pulmonary artery, pulmonary vein and tracheae, the isostructural two dimensional image of bronchus are extracted in the artificial judgment adjustment, and this is carried out three-dimensional reconstruction, obtain the three dimensional computer modeling of the various pipeline configurations of lung's casting mold sample.
3, carrying out associated picture among the electronic 3-D model importing image processing software 3-Matic with acquired lung casting mold sample handles, comprise surface smoothing, reduce processing such as tri patch, defect repairing, make model more true to nature, and design the color and the scaling of each structure.
4, will be as calculated the three dimensional computer modeling of lung's casting mold sample of crossing of machine Flame Image Process import and make lung casting mold sample model among the three-dimensional printer Z-Corp.On computer picture, represent the pulmonary vein in the lung casting mold sample model with the red pulmonary artery in lung's casting mold sample model, the blueness represented respectively, white is represented structures such as tracheae in the lung casting mold sample model, bronchus, Li Ti model is more directly perceived clear like this, make things convenient for medical teaching, facilitate for structure situation such as the pulmonary artery of understanding operation patients in advance, pulmonary vein and tracheae, bronchuses, improve success rate of operation.
Embodiment two: introduce according to the band bone of human body specimen and the shank scan-data of artery structure, make the process of the shank casting mold sample model of band bone and artery structure.
1, the shank to human body specimen carries out CT scan or 3 D laser scanning, obtains the faultage image data of shank structure.
2, the continuous faultage image data with the shank structure imports among the three-dimensional reconstruction software Mimics, adopt different threshold values that bone and artery structure are carried out " Threshold Segmentation " respectively, and functions such as modification of employing two dimensional image and region growing, realize the image segmentation of faultage image, skin, muscle, nerve fiber etc. in the deleted image, extract the two dimensional image of focile, artery structure, and this is carried out three-dimensional reconstruction, obtain the three dimensional computer modeling of shank casting mold sample.
3, carrying out associated picture among the electronic 3-D model importing image processing software 3-Matc with acquired shank casting mold sample handles, comprise surface smoothing, reduce processing such as tri patch, defect repairing, make model more true to nature, and design the color and the scaling of focile and artery structure.
4, will be as calculated the three dimensional computer modeling of the shank casting mold sample crossed of machine Flame Image Process import and make shank casting mold sample among the three-dimensional printer Z-Corp.With the white bone structure of representing in the shank casting mold sample, redness is represented the artery structure in the shank casting mold sample, and is so more directly perceived clear, makes things convenient for medical teaching, and understands operation patients bone and artery structure situation in advance, improves success rate of operation respectively.
Need to prove that patent of the present invention is also protected the casting mold sample model that adopts the inventive method to produce, the material of making comprises 3 D-printing material, medical bone cement, medical denture base material etc., macromolecule injected plastics material etc.Certainly also can adopt the inventive method to produce the casting mold sample model of different animals for those skilled in the art person, the method principle is all the same just not to be repeated here.These casting mold sample models of producing different animals all belong to protection scope of the present invention.
Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention, can also make some improvement and change, these improvement and change also are considered as protection scope of the present invention.
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| CN 201010285436 CN101964155A (en) | 2010-09-16 | 2010-09-16 | Method for manufacturing anthropotomy cast specimen model |
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| CN 201010285436 CN101964155A (en) | 2010-09-16 | 2010-09-16 | Method for manufacturing anthropotomy cast specimen model |
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| CN101964155A true CN101964155A (en) | 2011-02-02 |
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| CN 201010285436 Pending CN101964155A (en) | 2010-09-16 | 2010-09-16 | Method for manufacturing anthropotomy cast specimen model |
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