CN101940817A

CN101940817A - Light-medicine-combined treatment device for skin ulcers

Info

Publication number: CN101940817A
Application number: CN 201010280607
Authority: CN
Inventors: 宓现强; 钟福清
Original assignee: University of Shanghai for Science and Technology
Current assignee: University of Shanghai for Science and Technology
Priority date: 2010-09-14
Filing date: 2010-09-14
Publication date: 2011-01-12
Anticipated expiration: 2030-09-14
Also published as: CN101940817B

Abstract

A skin ulcer treatment device combined with photopharmaceuticals, which includes an outer cladding, a luminous layer, a drug patch layer, and a light parameter controller. The outer cladding is the basic structural part of the entire device, which is made of flexible materials and is located on the outermost layer. The drug patch layer is located in the innermost layer, and it is paved with externally applied drugs for treating skin ulcers. The light-emitting layer is located between the outer cladding layer and the drug patch layer, and includes optical fiber cloth and several LED light-emitting devices. The LED light-emitting devices are connected to the Around the fiber cloth, the light parameter controller is electrically connected with the LED lighting device, and controls the lighting parameters of the LED lighting device. The invention realizes a unique treatment method combining LED light irradiation and external application of medicines, has the advantages of remarkable effect, simple operation and convenient portability, and is suitable for the treatment of skin ulcers.

Description

The bonded skin ulcer therapy equipment of light medicine

Technical field:

The present invention relates to a kind of medical apparatus and instruments for the treatment of skin ulcer, relate in particular to the bonded skin ulcer therapy equipment of a kind of smooth medicine.

Background technology:

Skin ulcer is damaged for what caused by corium or deep skin disorganization, generally leaves cicatrix after more, and different with erosion, ulcer is secondary lesion, and the infringement that every skin injury, infection or tuberosity ulceration reach certain depth all can cause the generation of ulcer.Skin ulcer generally is that the limitation skin histology that is caused by infected by microbes, disturbance of blood circulation and delayed ischemic neurological deficits, immunologic dysfunction or congenital skin injury etc. after the wound is damaged, and these serious symptom ground influence people's work and life.Traditional therapy is a pharmacotherapy at present, treats these diseases by for oral administration or local external application medicine thing.But the drug effect of oral medicine is slow, and medicine is to transmit by blood circulation to spread all over whole body, therefore the whole efficiency of medicine is not high, also can cause the healthy position of human body to be subjected to side effects of pharmaceutical drugs simultaneously, thus the shortcoming of oral drug therapy skin ulcer be the course of treatment long, side effect big, Drug resistance etc. occurs.

Along with the develop rapidly of semiconductor technology, (Lighting Emitting Diode, LED) application at biomedical aspect enlarges the light emitting diode of various wavelength day by day.(630～1,000nm) the interior LED irradiation of scope has been found in multiple biological regulating action can have been arranged in cell culture and the animal model far infrared near infrared spectrum.Breadboard data show the mitochondrion oxidative metabolism of 670nmLED irradiation can raising cultured cell in vitro, and wherein LED is also extensively applied to the photon medical field as a kind of new clean and effective energy., be used to people's disease treatment and health care of body field in recent years more and more because light therapy apparatus has that effect is obvious, but the good repetitive therapy of the suitability, patient are used no pain, environmental protection, characteristics such as easy to use.Currently occurred miscellaneous optical dynamic therapy equipment on the market, be widely used in beauty treatment, as the Quantum SR that U.S. Luminous company produces, its light source is an xenon lamp; The Omnilux HONGGUANG photodynamic therapeutic instrument produced of Instr Ltd. of Britain Micron Technology and for example, its light source is a light emitting diode matrix, exports narrow spectrum HONGGUANG.The characteristics of these equipment are that bulky, inconvenience is carried, the patient must lie in or be sitting in the instrument next door when receiving treatment, patient's activity is restricted, in addition, these phototherapy apparatuss all can only be implemented single Photon Thherapy, well do not cooperate with Drug therapy, thereby limited room for promotion the skin ulcer curative effect.

At present, do not see as yet on the market have utilize LED light combine with liniment the treatment skin ulcer medical treatment device.

Summary of the invention:

For overcome present oral drug therapy skin ulcer course of treatment long, side effect is big, Drug resistance and shortcomings such as the Photon Thherapy curative effect is single, equipment heaviness, the invention provides the bonded skin ulcer therapy equipment of a kind of smooth medicine, the method that it adopts light emitting diode (LED) light source irradiation to combine with the medicine external application, reach the purpose for the treatment of skin ulcer effectively, the present invention has remarkable, the simple, convenient advantage of carrying of effect.

It is as follows that the present invention solves the technical scheme that its technical problem takes:

The bonded skin ulcer therapy equipment of a kind of smooth medicine, it comprises surrounding layer, luminescent layer, patche layer and optical parameter controller, described surrounding layer is the base structure part of whole device, it is made by flexible material and is positioned at outermost layer, described patche layer is positioned at innermost layer, it is equipped with the liniment of treatment skin ulcer, described luminescent layer is between this surrounding layer and patche layer, it comprises optical fiber cloth and some LED light-emitting devices, this LED light-emitting device be connected in this optical fiber cloth around, described optical parameter controller is electrically connected with described LED light-emitting device, and controls the luminous parameters of this LED light-emitting device.

The bonded skin ulcer therapy equipment of smooth medicine of the present invention also comprises magic tape, and this magic tape is connected on the edge of described surrounding layer, and this surrounding layer is made by medical canvas; Described optical fiber cloth intersects, walks up and down braiding in length and breadth by multiple beams of optical fiber and forms, and this optical fiber is made of the optical transmission core at center and the oversheath on surface, and its oversheath near patche layer one side is carried out damaged the processing; The luminous wavelength of described LED light-emitting device is 670 ± 10nm, and the mobility scale of its luminous parameters is: optical power density 3mw/cm ²～10mw/cm ²0～24 hour time, this LED light-emitting device includes pin, LED lamp and support, this pin is connected on the described LED lamp and by lead and is connected with described optical parameter controller, this LED lamp is provided with the transparent epoxy resin encapsulation, itself and described optical fiber are individually fixed on the described support, and medial surface and its medial surface that this support is fixed in described surrounding layer are provided with the reflectorized material coating; Described patche layer includes outer impervious barrier, inner medicine layer and the layer of attracting deposit, and this layer of attracting deposit is folded between described impervious barrier and the medicine layer; Described optical parameter controller includes electric power system, LCD display, shift knob, switching push button, subtracts button and add button, this electric power system is supplied this optical parameter controller with electric energy, this LCD display can show the luminous parameters of LED light-emitting device, and this luminous parameters comprises optical power density and time.

The present invention has realized a kind of unique Therapeutic Method of the brand-new skin ulcer that light emitting diode (LED) light source irradiation is combined with the medicine external application, compares with the light irradiation apparatus that can only realize traditional monotherapy or liniment, and it has following advantage:

1, evident in efficacy---device of the present invention promptly has the luminescent layer that can launch infrared light and comprises the patche layer that contains liniment again, the light of the 670nm unique wavelength that LED light-emitting device is wherein launched is to skin ulcer, skin burn, skin scald, acne, infect, symptoms such as pain have anti-inflammation detumescence, the analgesia spasmolytic, improve local blood circulation, adjust neural and the raising immunologic function, dredging the meridian, the effect of QI and blood regulating, and the liniment of special for treating skin ulcer can change partial pathology environment, promote cell proliferation, the growth of acceleration cambium promotes tissue ripe.The bonded skin ulcer therapy equipment of described smooth medicine makes that illumination and drug application act on simultaneously, the curative effect stack, therefore elkodermatosis is had fast, the good remarkable therapeutic effect in back more of short treating period, rehabilitation.

2, easy to carry---light-emitting device of the present invention has adopted small-sized LED lamp, softish optical fiber cloth and medical canvas surrounding layer; whole device can fold; be easy to carry; the defective that overcome existing Phototherapeutic device heaviness, can not carry; can realize the patient being received treatment whenever and wherever possible or changing dressings; not only do not influence patient's normal activity, and greatly reduce medical expense.

3, simple to operate---integral body of the present invention is folding cloth band shape, therefore can wrap up flexibly according to the different sizes of patient's affected part, the concrete condition of position, nexine patche layer is removable disposable drug paster simultaneously, thereby the bonded skin ulcer therapy equipment of described smooth medicine has the advantage of the usefulness of being simple and easy to, and can realize the comprehensive ring-type irradiation and the external application for curing of 360 ° of random times to patient's lesions position.

In a word, compared with conventional device and therapy, device of the present invention has remarkable, the simple, convenient advantage of carrying of effect to the treatment of elkodermatosis.

Description of drawings:

Fig. 1 is a schematic appearance of the present invention.

Fig. 2 is an internal structure sketch map of the present invention.

Fig. 3 is the schematic cross-section of structure of the present invention.

Fig. 4 is the schematic cross-section of optical fiber cloth.

Fig. 5 is the braiding structure sketch map of optical fiber cloth.

Fig. 6 is the structural representation of LED light-emitting device.

Fig. 7 is the front schematic view of optical parameter controller.

Fig. 8 is the reverse side sketch map of optical parameter controller.

Fig. 9 is the structural representation of patche layer.

The specific embodiment:

Now with specific embodiment the present invention is done detailed explanation in conjunction with the accompanying drawings.

At first please in conjunction with consulting Fig. 1,2 and 3 structural representations of the present invention, diagram light medicine bonded skin ulcer therapy equipment is that a kind of LED of utilization light combines with liniment and treats the medical treatment device of skin ulcer, and it comprises surrounding layer 1, luminescent layer, patche layer 4, optical parameter controller 5 and magic tape 6.

The base structure part that described surrounding layer 1 is whole device is " shell ", mainly is the stability that is used for fixing described luminescent layer and keeps whole apparatus structure.This surrounding layer 1 is made as medical canvas by flexible material, and is positioned at the outermost layer (see figure 3) of whole device.This surrounding layer 1 some region surface impression has the coat of strengthening the property, this coat is mainly in order to strengthen the physical characteristic of surrounding layer 1 regional area, make it to have toughness, intensity, anti-skidding and comfortable, it is generally the composite bed that medicated napkin and the pressing of plastic film material form, and this plastic film material adopts polyethylene from high pressure process and polyacrylic copolymer.This surrounding layer 1 some region surface has also impressed anti-liquid coat, and this anti-liquid coat comprises the hygroscopic material based on acrylic acid, has more intense moisture-absorption characteristics, can protect not liquid body pollution of user.

Described magic tape 6 is connected on the edge of described surrounding layer 1, and it has certain elasticity, can degree of tightness be wrapped in the affected part fitly.This magic tape 6 is sewed with three groups, and its hook face is sewn on the edge of surrounding layer 1 side by side, and the length of this hook face is 15cm, and width is 30mm, and the hair side of this magic tape 6 is all sewed in the outside of surrounding layer 1.

Described patche layer 4 is positioned at the innermost layer (see figure 3), can be made into the disposable paster that can change, and it is equipped with the liniment of treatment skin ulcer.See also Fig. 9 again, described patche layer 4 includes impervious barrier 41, medicine layer 42 and attracts deposit layer 43.These impervious barrier 41 positions are outer, and it is made by macromolecular material, as polyethylene film, dacron membrane etc., also can adopt latex film, aluminium foil etc. to make, and this impervious barrier 41 can prevent that drug leakage is to luminescent layer.These medicine layer 42 positions are inner and directly contact with human body surface, be equipped with the medicinal liquid of colloidal above, as rarer fluid extract etc., this medicinal liquid is made of quantitative medicine and adjuvant, can change local skin the pathology environment, promote cell proliferation, quicken the cambium growth.This layer of attracting deposit 43 is folded between described impervious barrier 41 and the medicine layer 42, is made by materials such as sponge or flannelette, gauze, Cotton Gossypiis, and its effect is absorption and storage compartment medicine, and certain patche layer 4 also can not established and attract deposit layers 43.

Described luminescent layer is between described surrounding layer 1 and patche layer 4, and it comprises optical fiber cloth 3 and some LED light-emitting devices 2.See also Fig. 5, described optical fiber cloth 3 intersects, walks up and down equably braiding in length and breadth by multiple beams of optical fiber 31 and forms, and it is flexible and can folds, and effective irradiation area of this optical fiber cloth 3 is roughly the rectangle of 30cm * 20cm.See also Fig. 4 again, described optical fiber 31 is made of the optical transmission core 311 at center and the oversheath 312 on surface, on the optical fiber cloth 3 that it is woven into, this optical fiber 31 is carried out damaged the processing near the oversheath 312 of patche layer 4 one side, as etching, strike off etc., promptly make it the damage that along its length discrete location place forms machinery, chemistry or other type; So the purpose of handling is, makes light L that LED light-emitting device 2 sends when optical fiber 31 length directions transmits, can an easier side from close patche layer 4, and promptly the side towards patient skin transmits, thereby makes the efficient of illumination higher.Described some LED light-emitting devices 2 be connected in this optical fiber cloth 3 around, see also Fig. 6, each LED light-emitting device 2 includes pin 21, LED lamp 22 and support 24.This LED lamp 22 is provided with the transparent epoxy resin encapsulation, and it is fixed on the described support 24, and this LED lamp 22 can be launched specific light, and its wavelength is 670nm, and the degree of bias is no more than 10nm up and down.This pin 21 is connected on the described LED lamp 22 and by lead 51 and is connected with described optical parameter controller 5.This support 24 is fixed in the medial surface of described surrounding layer 1, described optical fiber 31 also be fixed on this support 24 and the position near LED lamp 22.Thereby by support 24, whole LED light-emitting device 2 and optical fiber cloth 3 are fixed on the medial surface of surrounding layer 1, and when LED lamp 22 sends the light time, light L just can enter the also transmission on edge of optical fiber 31, and then makes monoblock optical fiber cloth 3 luminous.These support 24 medial surface are provided with reflectorized material coating 23, and this reflectorized material coating 23 plays a part optically focused and energy-conservation.

See also the sketch map of Fig. 7 and Fig. 8 optical parameter controller, described optical parameter controller 5 is electrically connected with described LED light-emitting device 2 by lead 51, the luminous parameters that it can provide electric energy and control this LED light-emitting device 2 for LED light-emitting device 2.This optical parameter controller 5 includes electric power system, LCD display 53, shift knob 54, switching push button 55, subtracts button 56 and add button 57.This electric power system provides this optical parameter controller 5 with electric energy, and it is the electric power system of rechargeable type, and once abundance can be powered 3～6 hours; This electric power system comprises Concealable two-pin plug 52, opens during charging, can be folded down when not charging.This LCD display 53 can show the luminous parameters of described LED light-emitting device 2, this luminous parameters comprises the optical power density and the current residual irradiation time of Set For Current, and Show Styles is as P:5mw, T:3:15:36.This shift knob 54 is the on and off switch that are used for controlling whole device.The effect of switching push button 55 is that illumination parameter is set, and when switching to P, adjusts optical power density by the plus-minus button, when switching to T, adjusts the time of light exposure treatment by the plus-minus button.This subtracts button 56 and is used for reducing parameter, and this adds button 57 and is used for strengthening parameter.The mobility scale that optical parameter controller 5 can be controlled the luminous parameters of LED light-emitting device 2 realizations is: optical power density 3mw/cm ²～10mw/cm ², 0～24 hour time.

Claims

1. a skin ulcer treatment device combined with photopharmaceuticals, characterized in that: said treatment device comprises an outer cladding, a luminous layer, a drug patch layer and an optical parameter controller, and said outer cladding is a basic structural part of the whole device, which Made of flexible materials and located in the outermost layer, the drug patch layer is located in the innermost layer, which is laid with externally applied drugs for treating skin ulcers, and the light-emitting layer is located between the outer covering layer and the drug patch layer, which includes Optical fiber cloth and several LED lighting devices, the LED lighting device is connected around the fiber cloth, the optical parameter controller is electrically connected with the LED lighting device, and controls the lighting parameters of the LED lighting device.

2. The skin ulcer treatment device combined with photopharmaceuticals according to claim 1, characterized in that: the optical fiber cloth is woven from multiple bundles of optical fibers that intersect vertically and horizontally and travel up and down, and the optical fiber is composed of a central light transmission core and a surface. Outer sheath composition.

3. The photopharmaceutical-combined skin ulcer treatment device according to claim 2, characterized in that: the outer sheath on the side of the optical fiber close to the drug patch layer is damaged.

4. The skin ulcer treatment device combined with photopharmaceuticals according to claim 2 or 3, characterized in that: said LED lighting device includes pins, LED lights and brackets, the pins are connected to said LED lights and The LED lamp and the optical fiber are respectively fixed on the bracket by connecting with the optical parameter controller through the wire, and the bracket is fixed on the inner surface of the outer cladding.

5. The photopharmaceutical-combined skin ulcer treatment device according to any one of claim 4, characterized in that: the LED lamp is provided with a transparent epoxy resin package, and the inner surface of the bracket is provided with a reflective material coating .

6. The skin ulcer treatment device combined with photopharmaceuticals according to any one of claims 1 to 5, characterized in that: the wavelength of light emitted by the LED light-emitting device is 670±10nm, and the fluctuation range of its light-emitting parameters is: light The power density is 3mw/cm ² -10mw/cm ² , and the time is 0-24 hours.

7. The skin ulcer treatment device combined with photopharmaceuticals according to claim 1, characterized in that: the drug patch layer includes an outer anti-seepage layer and an inner drug layer.

8. The skin ulcer treatment device combined with photopharmaceuticals according to claim 7, characterized in that: the drug patch layer also includes a suction reservoir, and the suction reservoir is sandwiched between the anti-seepage layer and the drug layer between.

9. The skin ulcer treatment device combined with light and medicine according to claim 1, characterized in that: the light parameter controller includes a power supply system, an LCD display, a switch button, a switch button, a minus button and a plus button, the power supply The system supplies the light parameter controller with electric energy, and the LCD display can display the lighting parameters of the LED lighting device, and the lighting parameters include light power density and time.

10. The skin ulcer treatment device combined with photopharmaceuticals according to claim 1, characterized in that: the treatment device also comprises a Velcro, which is connected to the edge of the outer cladding, and the outer cladding consists of Made of medical canvas.