CN101940652B - Chinese medicinal liniment for treating psoriasis, multiple kinds of stubborn dermatitis and pruritus - Google Patents
Chinese medicinal liniment for treating psoriasis, multiple kinds of stubborn dermatitis and pruritus Download PDFInfo
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- CN101940652B CN101940652B CN201010268850.1A CN201010268850A CN101940652B CN 101940652 B CN101940652 B CN 101940652B CN 201010268850 A CN201010268850 A CN 201010268850A CN 101940652 B CN101940652 B CN 101940652B
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Abstract
The invention relates to a Chinese medicinal liniment for treating psoriasis, multiple kinds of stubborn dermatitis and pruritus. At present, most medicaments for treating the psoriasis, multiple kinds of stubborn dermatitis and pruritus belong to immunosuppressive agents and have the adverse effect on the normal immunologic function. The Chinese medicinal liniment comprises the following medicaments by weight: 90 to 110 grams of rhubarb, 140 to 160 grams of pricklyash peel, 40 to 60 grams of Chinese mugwort leaf, 90 to 110 grams of lightyellow sophora root, 90 to 110 grams of shrubalthea bark, 70 to 90 grams of garden balsam stem, 140 to 160 grams of chaulmoogratree seed and 90 to 110 grams of erythrina indica lam. A preparation method comprises the following steps of: grinding the Chinese medicinal herbs into 150 to 200-mesh powder, adding 1,000 milliliters of 95 percent ethanol for stirring, and immersing the mixture for 24 hours; and extracting filter liquor, adding 4,000 milliliters of 50 percent ethanol into filter residues for stirring, immersing the mixture for 24 hours, extracting filter liquor, merging the two-time filter liquor, and mixing uniformly for packaging to obtain the Chinese medicinal liniment. The Chinese medicinal liniment is used for treating the psoriasis, multiple kinds of stubborn dermatitis and pruritus.
Description
technical field:
the present invention relates to a kind of Traditional Chinese medicine liniment for the treatment of psoriasis, various stubborn dermatitis, pruritus.
background technology:
psoriasis, various stubborn dermatitis, pruritus are very common chronic dermatosis.Doctor trained in Western medicine it be unclear that the psoriasic cause of disease, also without a kind of medicine, can reach radical cure at present.Many patients when treatment psoriasis, various stubborn dermatitis, pruritus owing to not following medication requirement, not only do not improve disease symptoms, missed on the contrary best treatment opportunity, treatment time is long, the medicine for the treatment of belongs to immunosuppressant class mostly at present, and normal immunologic function is had to harmful effect, if blindness long-term prescription, can make the lower for the resistance of patient, have a strong impact on treatment.
current medicine and method mainly contain following several
1. steroid hormone: corticosteroid hormone ointment (frost) external has 20 years history.Potent steroid hormone ointment (frost) external is clean, instant effect, but drug withdrawal easily recurs, and life-time service side effect increases, thus a lot of doctor's tendency need not, or only short-term, be interrupted and use.The intensity of medicine has very large difference, from mild to super strong type.The intensity of hormone has determined how long the skin in which region can not have side effects with using in medication.After excessively using, common side effect comprises thinning of skin, stretches cicatrix, and the Drug resistance to this hormone.
suppress DNA class medicine: its side effect is little, but the psoriatic lesion normal skin around that can stimulate or burn.
phototherapy (UVB): treat psoriatic lesion general hair style or local obstinate type with Type B ultraviolet (UVB) under doctor's specialized guidance.Can combine use with external medication method.There is very little risk to use in a short time UVB.The risk of life-time service UVB is the same with being exposed to the sun in the sun: skin carcinoma and skin aging.Short-term is used the side effect of PUVA to common are stomach discomfort, and skin rubefaction is itched.Life-time service can increase trouble skin splash, skin senilism, the chance of cataract etc.To accepting for a long time the patient's of PUVA treatment repeatedly investigation, show, after life-time service PUVA therapy, can cause suffering from the risk of some skin carcinoma.
above-mentioned treatment medicine and method are mainly to eliminate symptom, avoid further deterioration, cannot effect a radical cure.Side effect is larger, uses and wants prudent.
summary of the invention:
the object of this invention is to provide a kind of Traditional Chinese medicine liniment for the treatment of psoriasis, various stubborn dermatitis, pruritus, evident in efficacy, and after recovery from illness, be difficult for recurrence, patient no longer needs life-time service medicine to maintain, and does not develop immunity to drugs.
above-mentioned object realizes by following technical scheme:
treatment psoriasis, various stubborn dermatitis, the Traditional Chinese medicine liniment of pruritus, its Chinese medicine consists of: Radix Et Rhizoma Rhei, Pericarpium Zanthoxyli, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Shrubalthea Bark, Herba speranskiae tuberculatae, Semen Hydnocarpi, Cortex erythrinae, its weight is: Radix Et Rhizoma Rhei 90g-110g, Pericarpium Zanthoxyli 140g-160g, Folium Artemisiae Argyi 40g-60g, Radix Sophorae Flavescentis 90g-110g, Shrubalthea Bark 90g-110g, Herba speranskiae tuberculatae 70g-90g, Semen Hydnocarpi 140g-160g, Cortex erythrinae 90g-110g, described Chinese herbal medicine powder is broken into 150-200 order, adding 95% ethanol 1000ml stirs, flood 24 hours, extract filtrate, filtering residue adds 50% ethanol 4000ml again and stirs, flood 24 hours, extract again filtrate, merge filtrate twice, mix packing, obtain.
beneficial effect:
1. psoriasis, various stubborn dermatitis, pruritus initial stage are caused by wind, wet, pathogenic heat retardance skin, so that QI-blood circulation loses freely, with the passing of time consume impairment of YIN blood, seek deficiency of YIN, and wind syndrome due to blood-deficiency, dryness-transformation, due to failure of skin and muscle to be nourished.Method of the present invention dispeling the wind, heat clearing away, dampness, nourish blood, the poison that purifies the blood from source, thoroughly changes heat in blood, blood stasis, the dry phenomenon of blood, and opens a mao key, qi and blood circulation promotion, the poison that gets rid of illness, treating both the principal and secondary aspects of a disease.The present invention is by famous and precious natural Chinese medicine, and compatibility forms meticulously, drug utilization Du Genggao, more remarkable treatment effect.
this product is a kind of externally applied liniment, and during treatment, effect is good, evident in efficacy, and is difficult for recurrence after recovery from illness, and patient no longer needs life-time service medicine to maintain, and does not develop immunity to drugs.
this product is not containing the additives such as any hormone, Fructus Psoraleae, advantage without any side effects.
medicine of the present invention, through evidence safety non-toxic, has significant curative effect to treatment vitiligo, and its toxicology and pharmacodynamic experiment data are as follows:
skin irritation test: the stimulus intensity to rabbit skin belongs to nonirritant.Skin allergic reaction experiment: sensitization rate 0%, sensitization intensity belongs to extremely slightly degree.
long term toxicity test: respectively with 0.8g/kg, apply medicinal lotion or ointment to rat skin, every day three times, continuous 60 days, result of the test showed, the general state of tested rat, behavioral activity and diet situation and matched group are without significant difference; Hematology, liver function, renal function and organ coefficient and matched group, more all without significant difference, show that life-time service medicine of the present invention is safe.
carry out patient's clinical trial as follows: 150 routine psoriasiss, various stubborn dermatitis, pruritus patient patient are in Harbin Xian Chen dermatosis section hospital according to the degree of the state of an illness, and the patient of this medicine of clinical practice is divided into 3 groups, every group of 50 people.
, 50 routine psoriasiss, various stubborn dermatitis, pruritus patient are ill in 1 year, affected part is in 7cm2.Harbin Xian Chen dermatosis section hospital clinical practice 2 months, therapeutic effect was in Table 1:
the therapeutic effect of this medicine of table 1 to psoriasis, various stubborn dermatitis, pruritus patient:
50 routine psoriasiss, various stubborn dermatitis, pruritus patient are ill in 5 years, and affected part is in 10cm2.Harbin Xian Chen dermatosis section hospital clinical practice 6 months, therapeutic effect was in Table 2:
the therapeutic effect of this medicine of table 2 to psoriasis, various stubborn dermatitis, pruritus patient:
50 routine psoriasiss, various stubborn dermatitis, pruritus patient are ill in 10 years, and affected part is in 50cm2.Harbin Xian Chen dermatosis section hospital clinical practice 8 months, therapeutic effect was as follows:
the therapeutic effect of this medicine of table 3 to psoriasis, various stubborn dermatitis, pruritus patient
patient's clinical manifestation: its symptom is normal or filbert flat little scrofula from the beginning of color of the leather, surperficial glimmer, of a specified duration increasing gradually merged in flakes, pachyderma, sulci of skin is deepened, dry coarse, is lichen sample and becomes, and desquamation, very itches, and pain is not known in scratching of having.Also there are the coin of being shape, map shape in sick place, return shape, has individually vesicle, crowfoot cracks etc.Different parts, symptom differs, and outbreak, increases the weight of year by year repeatedly.
the standard of medical effect evaluation: effectively: 1, just sloughed the sclerderm dead bark of body surface, the skin wounds of chapping also starts rapid healing, and pruritus alleviates, squama reduces.2, focus area reducing, is linked to be large stretch of tinea piece originally and has become the red point isolating one by one, and squama further reduces, and sufferings sense is most of to disappear.3, there is gloss in skin, basic recovery normally, and scratchiness disappears substantially.4, sufferings sense disappears completely, and cutaneous pigmentation disappears, and it is normal that recover completely at skin lesion position.
statistical result: effective 95%, fully recover 80%, invalid 5%.
result shows: medicine of the present invention can obviously be treated psoriasis, various stubborn dermatitis, pruritus.
the specific embodiment:
embodiment 1:
treatment psoriasis, various stubborn dermatitis, the Traditional Chinese medicine liniment of pruritus, its Chinese medicine consists of: Radix Et Rhizoma Rhei, Pericarpium Zanthoxyli, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Shrubalthea Bark, Herba speranskiae tuberculatae, Semen Hydnocarpi, Cortex erythrinae, its weight is: Radix Et Rhizoma Rhei 110g, Pericarpium Zanthoxyli 160g, Folium Artemisiae Argyi 60g, Radix Sophorae Flavescentis 110g, Shrubalthea Bark 90g, Herba speranskiae tuberculatae 70g, Semen Hydnocarpi 140g, Cortex erythrinae 90g, described Chinese herbal medicine powder is broken into 150-200 order, adding 95% ethanol 1000ml stirs, flood 24 hours, extract filtrate, filtering residue adds 50% ethanol 4000ml again and stirs, flood 24 hours, extract again filtrate, merge filtrate twice, mix packing, obtain.
embodiment 2:
treatment psoriasis, various stubborn dermatitis, the Traditional Chinese medicine liniment of pruritus, its Chinese medicine consists of: Radix Et Rhizoma Rhei, Pericarpium Zanthoxyli, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Shrubalthea Bark, Herba speranskiae tuberculatae, Semen Hydnocarpi, Cortex erythrinae, its weight is: Radix Et Rhizoma Rhei 90g, Pericarpium Zanthoxyli 140g, Folium Artemisiae Argyi 40g, Radix Sophorae Flavescentis 90g, Shrubalthea Bark 110g, Herba speranskiae tuberculatae 90g, Semen Hydnocarpi 160g, Cortex erythrinae 110g, described Chinese herbal medicine powder is broken into 150-200 order, adding 95% ethanol 1000ml stirs, flood 24 hours, extract filtrate, filtering residue adds 50% ethanol 4000ml again and stirs, flood 24 hours, extract again filtrate, merge filtrate twice, mix packing, obtain.
embodiment 3:
treatment psoriasis, various stubborn dermatitis, the Traditional Chinese medicine liniment of pruritus, its Chinese medicine consists of: Radix Et Rhizoma Rhei, Pericarpium Zanthoxyli, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Shrubalthea Bark, Herba speranskiae tuberculatae, Semen Hydnocarpi, Cortex erythrinae, its weight is: Radix Et Rhizoma Rhei 100g, Pericarpium Zanthoxyli 150g, Folium Artemisiae Argyi 50g, Radix Sophorae Flavescentis 100g, Shrubalthea Bark 100g, Herba speranskiae tuberculatae 80g, Semen Hydnocarpi 150g, Cortex erythrinae 100g, described Chinese herbal medicine powder is broken into 150-200 order, adding 95% ethanol 1000ml stirs, flood 24 hours, extract filtrate, filtering residue adds 50% ethanol 4000ml again and stirs, flood 24 hours, extract again filtrate, merge filtrate twice, mix packing, obtain.
using method:
with gauze or absorbent cotton, be stained with a small amount of medicinal liquid, in affected part, massage gently wiping (contributing to like this absorption of medicine), during use in winter, preferably liquid medicine can be scalded, to give full play to drug effect.Apply medicinal lotion or ointment every day 2-3 times, any time external all can, apply medicinal lotion or ointment at least 2 hours time in affected part every day.Note keeping the dry of position of applying medicinal lotion or ointment.While applying medicinal lotion or ointment, do not exert oneself very much, in order to avoid cause skin injury.
Claims (1)
1.
a kind of psoriasis for the treatment of, various stubborn dermatitis, the Traditional Chinese medicine liniment of pruritus, its Chinese herbal medicine consists of: Radix Et Rhizoma Rhei, Pericarpium Zanthoxyli, Folium Artemisiae Argyi, Radix Sophorae Flavescentis, Shrubalthea Bark, Herba speranskiae tuberculatae, Semen Hydnocarpi, Cortex erythrinae, it is characterized in that: its weight is: Radix Et Rhizoma Rhei 90g-110g, Pericarpium Zanthoxyli 140g-160g, Folium Artemisiae Argyi 40g-60g, Radix Sophorae Flavescentis 90g-110g, Shrubalthea Bark 90g-110g, Herba speranskiae tuberculatae 70g-90g, Semen Hydnocarpi 140g-160g, Cortex erythrinae 90g-110g, described Chinese herbal medicine powder is broken into 150-200 order, adding 95% ethanol 1000ml stirs, flood 24 hours, extract filtrate, filtering residue adds 50% ethanol 4000ml again and stirs, flood 24 hours, extract again filtrate, merge filtrate twice, mix packing.
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| CN101940652B true CN101940652B (en) | 2014-02-26 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102920829A (en) * | 2012-11-28 | 2013-02-13 | 陈丽芳 | Drug for treating psoriasis and preparation method thereof |
| WO2017146368A1 (en) * | 2016-02-25 | 2017-08-31 | 대구한의대학교산학협력단 | Composition for preventing or treating skin pruritus containing kalopanax pictus extract as active ingredient |
Citations (4)
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| CN101049368A (en) * | 2007-05-12 | 2007-10-10 | 韩艳军 | Oral and external remedy for curing psoriasis |
| CN101301354A (en) * | 2008-04-03 | 2008-11-12 | 魏芸 | Externally used medicinal liquor for treating psoriasis |
| CN101569703A (en) * | 2008-04-30 | 2009-11-04 | 王卿荣 | Traditional chinese medicine lotion |
| CN101623373A (en) * | 2009-08-14 | 2010-01-13 | 周大红 | Traditional Chinese medicine composition for treating psoriasis and preparation method thereof |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101049368A (en) * | 2007-05-12 | 2007-10-10 | 韩艳军 | Oral and external remedy for curing psoriasis |
| CN101301354A (en) * | 2008-04-03 | 2008-11-12 | 魏芸 | Externally used medicinal liquor for treating psoriasis |
| CN101569703A (en) * | 2008-04-30 | 2009-11-04 | 王卿荣 | Traditional chinese medicine lotion |
| CN101623373A (en) * | 2009-08-14 | 2010-01-13 | 周大红 | Traditional Chinese medicine composition for treating psoriasis and preparation method thereof |
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Owner name: HEILONGJIANG HENGFA PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: WANG XIANCHEN Effective date: 20140121 |
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