CN101934046B - Semifluid extract of deer foetus and preparation method thereof - Google Patents
Semifluid extract of deer foetus and preparation method thereof Download PDFInfo
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses the semifluid extract of deer foetus, which takes the deer foetus, deer born after the normal period of gestation and not fed by breast milk, American ginseng, medlar, eucommia bark, white paeony root, spina date seed, villous amomum fruit, safflower, echinacea, astragalus and honey as raw materials. The semifluid extract of deer foetus is prepared by the following steps of: pre-treating the deer foetus and the deer born after the normal period of gestation and not fed by the breast milk, preparing deer foetus powder and the powder of the deer born after the normal period of gestation and not fed by the breast milk from the deer foetus and the deer born after the normal period of gestation and not fed by the breast milk by adopting freeze-drying technology, compounding the deer foetus powder, the powder of the deer and the other components according to proportion, and performing bulking and sterilization to prepare the semifluid extract. The semifluid extract of deer foetus completely maintains the bioactive ingredients of the deer foetus and the deer born after the normal period of gestation and not fed by the breast milk, has the double effects of treatment and nourishing, and is particularly suitable to be taken by weak patients with immune dysfunction, female chronic pelvic inflammatory disease, leucopenia after cancer chemotherapy and radiotherapy, and the like.
Description
One, technical field
The present invention relates to Chinese medicine preparation, particularly a kind of is Embryo cervi paste of processing of raw material and preparation method thereof with Embryo cervi, tire deer and other Chinese herbal medicine.
Two, background technology
The Embryo cervi that China's traditional medicine is alleged is meant the still rudimentary amniotic fluid tire of skeleton that from 4 to 5 months doe abdomen of gestation, takes out, and because of it contains multiple biotic component to the human body beneficial, the traditional Chinese medical science uses it as the human body tonic always.
The Embryo cervi single uses and to focus on kidney-replenishing, is prone to cause that because of weak deficiency of YIN patient obeys Embryo cervi for a long time the human body negative and positive become estranged, so the traditional Chinese medical science is processed compound preparation often with Embryo cervi and other Chinese herbal medicine compatibility, makes its negative and positive mutual aid, body gentle.The tonic compound deer fetus ointment that discloses like the ZL00110263.X Chinese patent is exactly to add Mel by Embryo cervi with kinds of traditional Chinese medicines compatibilities such as Radix Panacis Quinquefolii, Fructus Lycii, the Cortex Eucommiae, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Fructus Amomi, Flos Carthamis to process, and has nourishing negative and positive, liver and kidney tonifying, nourishing blood to tranquillize the mind, be amusing appetizing and accent be freely through the feeling pulse effect.This Embryo cervi paste focuses on nourishing, through nourishing, to old, the physical weakness persons such as back and women puerperal that recover play the health invigorating effect greatly.But among the real weak crowd, many suffer from chronic disease, and wherein leukopenia etc. is the most common behind endocrine disturbance, women's chronic pelvic inflammatory disease, the carcinosis radiotherapy and chemotherapy.To suffering from the crowd of this type disease, do not remove disease, depend merely on and nourish that often effect is slow, be difficult for reaching ideal effect.And this type chronic disease leans on Western medicine to be difficult to cure, moreover obeys Western medicine for a long time human body is had side effect, causes new infringement easily.In addition, the used Embryo cervi of this Embryo cervi paste is immature amniotic fluid tire, and some bioactive ingredients is not as good as full grown tire deer; Moreover use primary high temperature boiling method, its active component suffers to destroy in various degree, and effect is not fully exerted.
Three, summary of the invention
The purpose of this invention is to provide a kind of being specially adapted to and take, have concurrently the Embryo cervi paste of treatment and nourishing double effects because of suffering from diseases such as leukopenia behind endocrine disturbance, women's chronic pelvic inflammatory disease and the carcinosis radiotherapy and chemotherapy person that causes the physical weakness.
Another object of the present invention provides the method for preparing of this Embryo cervi paste.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to above-mentioned disease; With reference to the modern pharmacological research achievement; The animal and plant medicine that screening has endocrine regulation balance, anti-inflammation, nourishing bone marrow, a hemopoietic function improvement is compatible with the component of above-mentioned deer embryo-contained tonifying cream, and adopts the modern Chinese medicine process technology to reduce the bioactive ingredients loss, the raising drug effect; Make the Embryo cervi paste of processing can treat disease, again can nourishing and fit keeping function.
Embryo cervi paste provided by the invention, its raw material is formed and weight proportion is: Embryo cervi (referring to 4-5 month amniotic fluid tire) powder 5-10 part, tire deer (breast milk is not eaten in mature life) powder 10-15 part, Radix Panacis Quinquefolii 5-15 part; Fructus Lycii 10-20 part, Cortex Eucommiae 10-20 part, Radix Paeoniae Alba 8-20 part; Semen Ziziphi Spinosae 10-20 part, Fructus Amomi 1-10 part, Flos Carthami 10-20 part; Echinacea 10-20 part, Radix Astragali 10-20 part, Mel 20-90 part.
The preferred feedstock of Embryo cervi paste of the present invention is formed and weight proportion is: 5 parts in Embryo cervi powder, 10 parts in tire deer powder, 10 parts of Radix Panacis Quinquefoliis, 15 parts of Fructus Lyciis, 15 parts of the Cortexs Eucommiae, 15 parts of the Radix Paeoniae Albas, 15 parts of Semen Ziziphi Spinosaes, 5 parts of Fructus Amomis, 15 parts on Flos Carthami, 15 parts of Echinaceas, 15 parts of the Radixs Astragali, 50 parts of Mel.
The method for preparing of Embryo cervi paste of the present invention may further comprise the steps:
(1) Embryo cervi and tire deer are cut open the belly, remove meconium, clean, be cut into the fragment that full-size is no more than 2cm respectively;
(2) in above-mentioned Embryo cervi and tire deer fragment respectively spray concentration be the rice vinegar of 3-6%, the sprinkling amount is the 5-10% of Embryo cervi and tire deer weight, stirs, and rice vinegar is immersed in Embryo cervi and the tire deer fragment, is to leave standstill 1-2 hour under the 5-10 ℃ of environment in temperature;
(3) Embryo cervi and the tire deer that step (2) handles be will pass through with Vacuum Freezing & Drying Technology and Embryo cervi and tire deer dry product processed respectively;
(4) above-mentioned Embryo cervi is become 120 order Embryo cervi powder and tire deer powder with tire deer dry product pulverize separately;
(5) above-mentioned Embryo cervi powder and tire deer powder and Radix Panacis Quinquefolii, Fructus Lycii, the Cortex Eucommiae, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Fructus Amomi, Flos Carthami, Echinacea, the Radix Astragali, Mel are prepared burden in said ratio;
(6) with after the Radix Panacis Quinquefolii in the above-mentioned batching, Fructus Lycii, the Cortex Eucommiae, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Fructus Amomi, Flos Carthami, Echinacea and the cleaning of Radix Astragali water, decocte with water three times adds the water of 10 times of weight the first time; Decocted 1.5 hours, second and third time respectively adds the water of 8 times of weight, and each decocted 1 hour; Merge three times decoction liquor, filter, left standstill 10 hours; Get supernatant, heating is condensed into the extractum that relative density is 1.2-1.3 (55 ℃ of survey);
(7) Mel in the above-mentioned batching is heated to boils, filter out impurities;
(8) Embryo cervi powder in the above-mentioned batching and tire deer powder are mixed with the extractum of step (6) and the Mel of step (7), be stirred into paste;
(9) paste of step (8) is used container filling, place sterilization tank, sterilized 30 minutes down, make finished product at 105 ℃.
Adopt rice vinegar that Embryo cervi and tire deer are carried out pretreatment in the above-mentioned method for preparing, can play the effect of removing abnormal flavour (because of Embryo cervi and tire deer can have abnormal flavour without the high temperature decoction), increase acceptable calcium matter, blood circulation promoting and blood stasis dispelling, dispersing the stagnated live-QI to relieve the stagnation of QI and inducting the medicines into affected channel, heightening the effect of a treatment.Adopting modern Freeze Drying Technique to replace traditional decocting method helps Embryo cervi and the processing of tire deer in the powder entering medicament; Can guarantee that the various effective ingredient of Embryo cervi and tire deer do not lose; The various bioactive substances that comprise tire Os Cervi marrow are not destroyed by long-time heat, and effect is improved.
Embryo cervi paste of the present invention has increased components such as Echinacea, the Radix Astragali and tire deer, and wherein Echinacea has facilitation to the human immune system, has antiinflammatory, anti-bacteria and anti-virus effect; Radix Astragali invigorating QI to consolidate the body surface resistance matches with Echinacea, not only can strengthen the former curative effect, and tumor cell is had inhibition and killing action; The tire deer is mainly used its bone marrow, has profit and supports the human bone marrow, promotes the effect of human body hematopoietic function.These components and former deer embryo-contained tonifying cream component are compatible, have both kept and improved the nourishing effects of former Embryo cervi paste, have increased again treatment of diseases effects such as leukopenia behind endocrine disturbance, women's chronic pelvic inflammatory disease and the carcinosis radiotherapy and chemotherapy.Clinical trial proves; To take Embryo cervi paste effect of the present invention particularly evident because of suffering from this type of disease person that causes the physical weakness: it can make disease treatment and two kinds of effects of nourishing and fit keeping function complement each other, bring out the best in each other; Efficacy exertion is fast, and the cycle of taking is short, and body constitution is strengthened; Premunition improves, and disease is difficult for recurrence.
Below for taking the clinical case of Embryo cervi paste of the present invention:
Case 1 Lee * *, the woman, 50 years old, the government functionary, because of insomnia, headache, Chang Buneng uncomfortable in chest, irritated adhere to working, examination in hospital does not have organic disease over 2 years, makes a definite diagnosis to belong to the endocrine regulation that climacteric estrogen decline causes.Take Embryo cervi paste of the present invention, every day is each 10 gram sooner or later, and subjective symptoms takes a turn for the better after two weeks, continues two weeks of clothes, and insomnia and headache symptom disappear basically, can adhere to working.Body & mind recovers normal after taking half a year, working always.
Case 2 enemy * *, the woman, 35 years old, the workman suffered from chronic pelvic inflammatory disease for many years, obstinate, inferior belly gas pain on ordinary days, leucorrhoea grow in quantity, menoxenia with the temperature rise of antibiotics control volume, is prone to after the drug withdrawal recur during acute attack, emaciated physique, face is sallow.Take Embryo cervi paste of the present invention, every day is each 10 gram sooner or later, and the conscious abdominal distention in two week backs, colic symptoms alleviate, and continues two weeks of clothes, and abdominal distention, colic symptoms are slight, and leucorrhea reduces, and takes resolution of symptoms after three months, and menstruation recovery is normal, medical inspection, and pelvic inflammatory disease heals.Continue to strengthen and take half a year, physical recovery is normal, weight increase, and face is improved.Followed up a case by regular visits to 1 year, pelvic inflammatory disease does not recur.
3 of cases * *, man, 56 years old; The government functionary, colon cancer operation back chemotherapy, blood leucocyte is reduced to 2.0 * 10^9/L; Take Embryo cervi paste of the present invention, every day is each 10 gram sooner or later, looks into leukocyte after two months and is raised to 3.0 * 10^9/L; Take half a year continuously, leukocyte rises to 4.3 * 10^9/L, reaches normal value.
Four, the specific embodiment
Embodiment
Prepare Embryo cervi paste by following step successively:
(1) gets 4 months the amniotic fluid Embryo cervi and the tire deer of mature life, cut open the belly, remove meconium, clean, be cut into the fragment that full-size is no more than 2cm respectively;
(2) in above-mentioned Embryo cervi and tire deer fragment respectively spray concentration be 5% rice vinegar, the sprinkling amount is 8% of Embryo cervi and a tire deer weight, with sprinkling; With stirring; Rice vinegar is fully mixed with Embryo cervi and tire deer fragment, immerse in Embryo cervi and the tire deer fragment, place 8 ℃ cold closet to preserve then 1.5 hours;
(3) Embryo cervi and the tire deer that step (2) handles be will pass through with vacuum freeze drier and Embryo cervi and tire deer dry product processed respectively;
(4) above-mentioned Embryo cervi and tire deer dry product are pulverized respectively, crossed 120 mesh sieves, process Embryo cervi powder and tire deer powder;
(5) by above-mentioned Embryo cervi powder 1Kg, tire deer powder 2Kg, Radix Panacis Quinquefolii 2Kg, Fructus Lycii 3Kg, Cortex Eucommiae 3Kg, Radix Paeoniae Alba 3Kg, Semen Ziziphi Spinosae 3Kg, Fructus Amomi 1Kg, Flos Carthami 3Kg, Echinacea 3Kg, Radix Astragali 3Kg, Mel 10Kg batching;
(6) Radix Panacis Quinquefolii in the above-mentioned batching, Fructus Lycii, the Cortex Eucommiae, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Fructus Amomi, Flos Carthami, Echinacea and Radix Astragali water are cleaned, add water 240Kg and decocted 1.5 hours, filter, get first-time filtrate with 20 mesh filter screens; To leach thing and continue to add respectively successively 192Kg water and carry out secondary and decoct for three times, decoct 1 hour at every turn, filter with 20 mesh filter screens; Three filtratings are merged, left standstill 10 hours, get supernatant, using dual concentrating instrument to be condensed into relative density is 1.2 extractum;
(7) Mel in the above-mentioned batching is heated to boils, remove floating foam, filter out impurities;
(8) Embryo cervi powder in the above-mentioned batching and tire deer powder are mixed with the extractum of step (6) and the Mel of step (7), be stirred into paste;
(9) the paste bottling that step (8) is made places sterilization tank, sterilizes 30 minutes down at 105 ℃, makes the Embryo cervi paste finished product.
This Embryo cervi paste is suitable especially, and the person takes because of diseases such as leukopenia behind trouble endocrine disturbance, women's chronic pelvic inflammatory disease and the carcinosis radiotherapy and chemotherapy cause the physical weakness, and usual amounts is day clothes twice, and each 10 grams are used warm boiled water sooner or later.
Need to prove; This Embryo cervi paste also can not add Mel and wear into fine powder behind the extract dry with above-mentioned steps (6); Prepare burden in said ratio with the Embryo cervi powder and the tire deer powder of step (4); Process powder, tablet, granule or soft capsule with different auxiliary material, the Embryo cervi goods of these dosage forms are all in protection scope of the present invention.
Claims (2)
1. an Embryo cervi paste is characterized in that the raw material composition and the weight proportion of this Embryo cervi paste is: Embryo cervi powder 5-10 part, tire deer powder 10-15 part, Radix Panacis Quinquefolii 5-15 part; Fructus Lycii 10-20 part, Cortex Eucommiae 10-20 part, Radix Paeoniae Alba 8-20 part; Semen Ziziphi Spinosae 10-20 part, Fructus Amomi 1-10 part, Flos Carthami 10-20 part; Echinacea 10-20 part, Radix Astragali 10-20 part, Mel 20-90 part; Its preparation method may further comprise the steps:
(1) Embryo cervi and tire deer are cut open the belly, remove meconium, clean, be cut into the fragment that full-size is no more than 2cm respectively;
(2) in above-mentioned Embryo cervi and tire deer fragment respectively spray concentration be the rice vinegar of 3-6%, the sprinkling amount is the 5-10% of Embryo cervi and tire deer weight, stirs, and rice vinegar is immersed in Embryo cervi and the tire deer fragment, is to leave standstill 1-2 hour under the 5-10 ℃ of environment in temperature;
(3) Embryo cervi and the tire deer that step (2) handles be will pass through with Vacuum Freezing & Drying Technology and Embryo cervi and tire deer dry product processed respectively;
(4) above-mentioned Embryo cervi is become 120 order Embryo cervi powder and tire deer powder with tire deer dry product pulverize separately;
(5) above-mentioned Embryo cervi powder and tire deer powder and Radix Panacis Quinquefolii, Fructus Lycii, the Cortex Eucommiae, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Fructus Amomi, Flos Carthami, Echinacea, the Radix Astragali, Mel are prepared burden in said ratio;
(6) with after the Radix Panacis Quinquefolii in the above-mentioned batching, Fructus Lycii, the Cortex Eucommiae, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Fructus Amomi, Flos Carthami, Echinacea and the cleaning of Radix Astragali water, decocte with water three times adds the water of 10 times of weight the first time; Decocted 1.5 hours, second and third time respectively adds the water of 8 times of weight, and each decocted 1 hour; Merge three times decoction liquor, filter, left standstill 10 hours; Get supernatant, heating is condensed into the extractum that relative density is 1.2-1.3;
(7) Mel in the above-mentioned batching is heated to boils, filter out impurities;
(8) Embryo cervi powder in the above-mentioned batching and tire deer powder are mixed with the extractum of step (6) and the Mel of step (7), be stirred into paste;
(9) paste of step (8) is used container filling, place sterilization tank, sterilized 30 minutes down, make finished product at 105 ℃.
2. Embryo cervi paste according to claim 1 is characterized in that its raw material is formed and weight proportion is: 5 parts in Embryo cervi powder, 10 parts in tire deer powder, 10 parts of Radix Panacis Quinquefoliis, 15 parts of Fructus Lyciis; 15 parts of the Cortexs Eucommiae, 15 parts of the Radix Paeoniae Albas, 15 parts of Semen Ziziphi Spinosaes, 5 parts of Fructus Amomis; 15 parts on Flos Carthami, 15 parts of Echinaceas, 15 parts of the Radixs Astragali, 50 parts of Mel.
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CN1102049C (en) * | 2000-03-29 | 2003-02-26 | 金龙亮 | Tonic compound deer fetus ointment and its preparation |
CN100363022C (en) * | 2004-06-04 | 2008-01-23 | 成都地奥制药集团有限公司 | Pharmaceutical composition with immunoregulation function and method for preparing the same |
CN100425270C (en) * | 2006-03-02 | 2008-10-15 | 魏峰 | Semifluid extract of deer foetus and preparing method |
CN101085236B (en) * | 2007-06-05 | 2010-08-04 | 王海阔 | Semifluid extract of deer foetus and preparation method thereof |
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