CN101862480B - Cardiac auxiliary volume amplifier - Google Patents
Cardiac auxiliary volume amplifier Download PDFInfo
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- CN101862480B CN101862480B CN2010102298746A CN201010229874A CN101862480B CN 101862480 B CN101862480 B CN 101862480B CN 2010102298746 A CN2010102298746 A CN 2010102298746A CN 201010229874 A CN201010229874 A CN 201010229874A CN 101862480 B CN101862480 B CN 101862480B
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- 230000000747 cardiac effect Effects 0.000 title claims abstract description 19
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- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
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Abstract
The invention relates to a cardiac auxiliary volume amplifier, which is characterized in that the amplifier comprises an amplifier shell and a double piston. An inner cavity of the amplifier shell comprises a driving cavity and a driven cavity, wherein the volume of the driven cavity is smaller than the volume of the driving cavity; the double piston is placed in the inner cavity of the amplifier shell and slides axially; and the amplifier shell is provided with an air inlet communicated with the driven cavity and an air outlet communicated with the driving cavity. The invention has the advantages that the volume amplifier has the principle of guiding the driving cavity with bigger volume to move for the same distance through the driven cavity with smaller volume and generating bigger volume through the driving cavity so as to amplify the volume. The friction generated by moving the piston can be reduced by using a film sealing ring. When treating a serious difficult treated heart failure, the auxiliary effect is obviously promoted and the circulation is more effectively assisted. The invention can make up the defect that an IABP air pump has insufficient volume.
Description
Technical field
The invention belongs to the cardiac mechanical auxiliary device, relate in particular to a kind of and pneumatic counter-pulsation device and link to each other, jumbo circulation support is provided, obviously improve the cardiac auxiliary volume amplifier of heart failure patient auxiliaring effect.
Background technology
Have among China adult and surpass 4,000,000 heart failure (annual medical expense has brought huge burden up to 10,000,000,000 yuans to the country and people for Heart failure, HF) patient.At present, can't obtain satisfied effect for severe and intractable HF Drug therapy; And heart transplantation receives the donor restriction.At present; The clinical auxiliary treating method of using always for serious difficult treated HF patient; The first is used axial flow blood pump and the effective assist circulation of centrifugal blood pump, but the excessively hemorrhage and not enough thrombosis of anticoagulant in back of anticoagulant, fatal severe complications such as the auxiliary back of left heart right heart failure possibly appear in the patient; It two is IABC (IABP), improves cardiac function through reducing afterload.IABP is because of implanting simple, safety, and is cheap, becomes clinical the most frequently used circulatory aid.But in its application process, clinical discovery has following shortcoming: 1. because descending aorta and sacculus capacity limitation, the hemodynamics that provides is supported limited, by force the cardiac function of dependent patient self and playing a role; 2. can not prolonged application (generally in 2 weeks) because the restriction patient is movable; 3. complication such as IABP implantable intravascular far-end ischemia and thrombosis possibly take place.In recent years; It is more and more to break away from cardiopulmonary bypass unit or wait heart transplantation or the heart patient in whole latter stage behind MSOF of severe acute cardiac or the operation on heart, and urgent need cardiac mechanical auxiliary device carries out the short-term transition or keeps the long period and wait for heart donor or auxiliary for a long time.Require the cardiac mechanical auxiliary device not only favorable durability will be arranged clinically, but also higher biocompatibility will be arranged.Clinically demand developing a kind of simple to operate, cheap heart-assist device urgently.And external large-artery side counterpulsation device has above-mentioned advantage, through using volume amplifier, can reach that high capacity is counter fights; Further reduce afterload, improve mean arterial pressure, keep effective circulation, reduce myocardial oxygen consumption; Suppress remodeling ventricle, increase coronary perfusion, promote cardiac muscle to recover; Obviously improve auxiliaring effect, obviously improve the perfusion of whole body important organ, accelerate the recovery of cardiac function.
Summary of the invention
The objective of the invention is to overcome the deficiency that the anti-auxiliary device high capacity of fighting of heart is difficult to drive, a kind of cardiac auxiliary volume amplifier is provided, it places external, is connected between IABP control station and the pneumatic counter-pulsation device, effectively the anti-capacity of fighting of raising.With the anti-capsule of fighting of the more suctions of large artery trunks inner blood, obviously reduce aortic systolic pressure at paradoxical expansion, reduce cardiac afterload, further reduce heart acting and myocardial oxygen consumption; Diastole is squeezed into the blood in the jumbo anti-capsule of fighting in the large artery trunks, obviously improves AoMP, further increases the hemoperfusion of arteria coronaria and surrounding tissue, obviously improves cardiac function.
The present invention is for realizing above-mentioned purpose; Realize through following technical scheme: a kind of cardiac auxiliary volume amplifier; It is characterized in that: mainly be made up of amplifier housing and double-piston, the inner chamber of said amplifier housing constitutes by actuator chamber with by actuator chamber two parts, by the volume of the volume of actuator chamber less than actuator chamber; Said double-piston places that intracavity endwisely slips in the amplifier housing, and said amplifier housing is provided with and air inlet that is communicated with by actuator chamber and the gas outlet that is communicated with actuator chamber
,Said double-piston connects into integral body by large and small piston solid phase, and the distance that large and small piston moves equates.
Said large and small piston outer rim is provided with film property sealing ring.
Said actuator chamber is provided with the assist gas inlet, and said assist gas inlet injects switch with manual adjustment and is connected.
Beneficial effect: the principle of volume amplifier is made actuator chamber (high capacity) mobile phase equidistant by actuator chamber (low capacity), and actuator chamber will produce more high capacity, reaches the effect that capacity amplifies.The friction that piston moves can be used film property sealing ring and reduced.This device is connected in IABP control station exhaust apparatus by the air inlet of actuator chamber, and the actuator chamber gas outlet is connected in the air bag pipeline of large-artery side counterpulsation pump, moves the completion capacity through valve piston to big piston and amplifies, and realizes that high capacity is counter to fight.At paradoxical expansion the large artery trunks inner blood is more sucked haematodocha, further reduce aortic systolic pressure, reduce cardiac afterload, reduce the heart acting, lower myocardial oxygen consumption; Diastole is squeezed into more blood in the haematodocha in the large artery trunks, obviously improves AoMP, further increases the perfusion of arteria coronaria and surrounding tissue organ, and assist circulation is more effectively improved the function of heart and each histoorgan of whole body.When treatment serious difficult treated heart failure,, obviously improved auxiliaring effect, more effective assist circulation owing to increased auxiliary capacity.It can remedy the shortcoming that the IABP air pump drives off-capacity.
Description of drawings
Fig. 1 is a structural representation of the present invention;
Among the figure: 1, amplifier housing, 2, inner chamber, 2-1, actuator chamber, 2-2,, 3, double-piston, 4, air inlet, 5, the gas outlet, 6, film property sealing ring, 7, gas injects switch, 8, the assist gas inlet by actuator chamber.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention.
See a kind of cardiac auxiliary volume amplifier of accompanying drawing for details; Mainly constitute by amplifier housing 1 and double-piston 3; The inner chamber 2 of said amplifier housing constitutes by actuator chamber 2-1 with by actuator chamber 2-2 two parts; By the volume of the volume of actuator chamber less than actuator chamber, said double-piston places that intracavity endwisely slips in the amplifier housing, and said amplifier housing is provided with and air inlet that is communicated with by actuator chamber 4 and the gas outlet 5 that is communicated with actuator chamber.Connected the outlet of inflating of IABP control station by the actuator chamber air inlet; The actuator chamber gas outlet connects on the air bag pipeline of large-artery side counterpulsation auxiliary device; Through inflating of IABP control station with air-breathing, the intravital double-piston of amplifier shell is endwisely slipped in cavity, the realization capacity amplifies; Said double-piston connects into integral body by large and small piston solid phase, and the distance that large and small piston moves equates.Said large and small piston outer rim is provided with film property sealing ring 6.The actuator chamber amplification capacity of inner chamber is 60-140mL.Said actuator chamber is provided with the assist gas inlet, and said assist gas inlet 8 injects switch 7 with gas and is connected.Actuator chamber assist gas capacity can inject the switch manual adjustment through the gas on actuator chamber surface, can select optimum capacity as required.
Work process: when using volume amplifier, get into by actuator chamber, drive double-piston and shift to actuator chamber from IABP control station expellant gas; Air vent through actuator chamber is squeezed into gas in the air bag of heart-assist device; Because of the actuator chamber volume greater than by actuator chamber, the piston mobile phase is equidistant, and jumbo gas in the actuator chamber is squeezed in the air bag of the anti-auxiliary device of fighting; Increase auxiliary tolerance, realize that high capacity is counter to fight.When a large amount of gases were discharged in the piston motion to the auxiliary device air bag, the volume that the driven plunger motion stays was greater than the volume that is occupied by driven plunger.Formed like this difference in volume just produces negative pressure in connection chamber.After the gases at high pressure of getting from the IABP control station were drawn back, just resorption double-piston and then the collaborative anti-auxiliary device of fighting were drawn back gas to the negative pressure that produces in the connection chamber rapidly.Actuator chamber assist gas capacity can inject the switch manual adjustment through the gas on actuator chamber surface; Press heart failure patient's body surface area, select optimum capacity, when reciprocating motion of the pistons; Just be full of blood and emptying blood in the anti-auxiliary device haematodocha of fighting, reach the optimal counter-pulsation effect.
Operation principle: move through double-piston, make by actuator chamber (low capacity) to make actuator chamber (high capacity) mobile phase equidistant, actuator chamber will produce more high capacity, reach the effect that capacity amplifies.
Animal experiment study
One, purpose: the high capacity large-artery side counterpulsation heart auxiliary device can improve the hemodynamics of low heart row animal more significantly, keeps effective circulation, improves cardiac function, increases perfused tissue.
Two, method: select the sheep (50-65 kg) that grows up for use, be divided into 2 groups, 4 every group, the auxiliary first group of 40ml of capacity of the anti-auxiliary device of fighting, second group of 80ml.In the identical large-artery side counterpulsation heart auxiliary device (first group of 40ml, second group of 80ml) of descending aorta, between auxiliary device and IABP control station, settle volume amplifier (because of the maximum auxiliary capacity of IABP control station can not surpass 60ml), improve auxiliary capacity.Set up the acute heart failure model; Relatively the auxiliary front and back of heart failure aortic pressure, left indoor pressure, pulmonary artery down pressure, cardiac output, carotid artery flow, coronary flow, crown arteriovenous blood oxygen saturation are calculated endocardium survival rate, left outdoor merit, myocardial oxygen consumption.
Three, result: acute heart failure, large-artery side counterpulsation heart auxiliary device can provide effective circulation support.After auxiliary, aortic systolic pressure descends, and AOD improves, and coronary flow increases, the ventricular systole drops, and the heart acting reduces, and cardiac output increases.Simultaneously, the carotid artery flow amount increases, and the Coronary vein blood oxygen saturation improves, and the endocardium survival rate increases, and left outdoor merit reduces, and myocardial oxygen consumption reduces.The result of high capacity (80ml) group is better, obviously is superior to low capacity (40ml) group.
Four, conclusion: the high capacity large-artery side counterpulsation heart auxiliary device lowers cardiac afterload through further reducing aortic systolic pressure, reduces the heart acting; Reduce myocardial oxygen consumption; Further improve mean arterial pressure, increase the relaxing period perfusion, improve cardiac function.According to the anti-capacity of fighting of the reasonable increase of body surface area, can obtain better auxiliaring effect.
The above only is preferred embodiment of the present invention, is not structure of the present invention is done any pro forma restriction.Every foundation technical spirit of the present invention all still belongs in the scope of technical scheme of the present invention any simple modification, equivalent variations and modification that above embodiment did.
Claims (3)
1. cardiac auxiliary volume amplifier; It is characterized in that: mainly constitute by amplifier housing and double-piston; The inner chamber of said amplifier housing constitutes by actuator chamber with by actuator chamber two parts; By the volume of the volume of actuator chamber less than actuator chamber, said double-piston places that intracavity endwisely slips in the amplifier housing, and said amplifier housing is provided with and air inlet that is communicated with by actuator chamber and the gas outlet that is communicated with actuator chamber; Said double-piston connects into integral body by large and small piston solid phase, and the distance that large and small piston moves equates.
2. cardiac auxiliary volume amplifier according to claim 1 is characterized in that: said large and small piston outer rim is provided with film property sealing ring.
3. cardiac auxiliary volume amplifier according to claim 1 is characterized in that: said actuator chamber is provided with the assist gas inlet, and said assist gas inlet injects switch with manual adjustment and is connected.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102298746A CN101862480B (en) | 2010-07-19 | 2010-07-19 | Cardiac auxiliary volume amplifier |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102298746A CN101862480B (en) | 2010-07-19 | 2010-07-19 | Cardiac auxiliary volume amplifier |
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| Publication Number | Publication Date |
|---|---|
| CN101862480A CN101862480A (en) | 2010-10-20 |
| CN101862480B true CN101862480B (en) | 2012-06-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010102298746A Active CN101862480B (en) | 2010-07-19 | 2010-07-19 | Cardiac auxiliary volume amplifier |
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| Country | Link |
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| CN (1) | CN101862480B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3842440A (en) * | 1972-09-01 | 1974-10-22 | E Karlson | Implantable linear motor prosthetic heart and control system therefor |
| US3885393A (en) * | 1973-09-07 | 1975-05-27 | Us Energy | Hydraulic load matching device |
| US5913814A (en) * | 1997-08-26 | 1999-06-22 | Belmont Instrument Corporation | Method and apparatus for deflation of an intra-aortic balloon |
| CN100534395C (en) * | 2004-06-30 | 2009-09-02 | 爱尔伯电子医疗设备公司 | Medical pump |
| CN201727776U (en) * | 2010-07-19 | 2011-02-02 | 刘晓程 | Heart auxiliary capacity expander |
-
2010
- 2010-07-19 CN CN2010102298746A patent/CN101862480B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3842440A (en) * | 1972-09-01 | 1974-10-22 | E Karlson | Implantable linear motor prosthetic heart and control system therefor |
| US3885393A (en) * | 1973-09-07 | 1975-05-27 | Us Energy | Hydraulic load matching device |
| US5913814A (en) * | 1997-08-26 | 1999-06-22 | Belmont Instrument Corporation | Method and apparatus for deflation of an intra-aortic balloon |
| CN100534395C (en) * | 2004-06-30 | 2009-09-02 | 爱尔伯电子医疗设备公司 | Medical pump |
| CN201727776U (en) * | 2010-07-19 | 2011-02-02 | 刘晓程 | Heart auxiliary capacity expander |
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| Publication number | Publication date |
|---|---|
| CN101862480A (en) | 2010-10-20 |
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Effective date of registration: 20200402 Address after: 300457 No.61, Third Street, economic and Technological Development Zone, Binhai New Area, Tianjin Patentee after: TEDA INTERNATIONAL CARDIOVASCULAR Hospital Address before: 300457 No. third, 61 Avenue, Tanggu economic and Technological Development Zone, Tianjin Patentee before: Liu Xiaocheng |
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| TR01 | Transfer of patent right |
Effective date of registration: 20201120 Address after: 300457 No.61, Third Street, economic and Technological Development Zone, Binhai New Area, Tianjin Patentee after: TEDA International Cardiovascular Hospital Co., Ltd Address before: 300457 No.61, Third Street, economic and Technological Development Zone, Binhai New Area, Tianjin Patentee before: TEDA INTERNATIONAL CARDIOVASCULAR Hospital |