CN101849868B - Self-controlled laser surgery equipment - Google Patents
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Abstract
Description
本发明是《自控激光手术设备》申请号:200810154587.6,申请日:2008年12月26日的分案申请。The present invention is a divisional application of "Automatic Control Laser Surgery Equipment" with application number: 200810154587.6 and application date: December 26, 2008.
技术领域 technical field
本发明涉及一种激光手术医疗器械,尤其涉及一种自控激光手术设备。The invention relates to a laser surgery medical instrument, in particular to an automatic control laser surgery equipment.
背景技术 Background technique
采用激光显微进行手术已被广泛应用,不仅是外科、内科、五官科以及眼科均广泛的使用,在治疗青光眼方面,采用激光显微手术是治疗的主要手段。传统的滤过性手术主要有小梁切除术、巩膜咬切术,但是传统的滤过性手术术后并发症较多,如早期的术后浅前房及无前房、睫脉脱、恶性青光眼、出血和滤过泡不形成等;晚期的滤过口堵塞、瘫痕形成、囊样变、滤过泡破裂、白内障和感染等。现有的激光显微手术系统主要是通过显微系统实时观察被激光照射生物组织的变化情况,根据手术所需,手动控制手术过程中的激光照射量,在消除病灶组织的同时常伴有并发症,影响治疗效果,所以,这些治疗设备和治疗方法必须一边观察手术情况,一边手动控制整个手术过程中的激光照射量,比较繁琐,绝大多数手术医生是凭借手术的经验进行激光手术,很难控制好手术,还存在诸多问题亟待解决。Laser microsurgery has been widely used, not only in surgery, internal medicine, ENT and ophthalmology, but in the treatment of glaucoma, laser microsurgery is the main method of treatment. Traditional filtering surgery mainly includes trabeculectomy and scleral bite, but there are many complications after traditional filtering surgery, such as early postoperative shallow anterior chamber and no anterior chamber, ciliary prolapse, malignant Glaucoma, hemorrhage and non-formation of filtering blebs, etc.; late stage filter opening blockage, scar formation, cystoid degeneration, rupture of filtering blebs, cataract and infection, etc. The existing laser microsurgery system mainly observes the changes of the biological tissue irradiated by the laser in real time through the microscopic system, and manually controls the amount of laser irradiation during the operation according to the needs of the operation. Therefore, these treatment equipment and treatment methods must observe the operation situation while manually controlling the amount of laser irradiation during the entire operation process, which is cumbersome. Most surgeons rely on their surgical experience to perform laser surgery. It is difficult to control the operation well, and there are still many problems to be solved urgently.
发明内容 Contents of the invention
本发明的主要目的在于解决上述激光手术医疗器械和激光手术中的问题,提供一种能够控制手术过程中消除病灶组织的同时不损伤正常组织,具有多种控制方式、参数可调、应用广泛,精确地控制手术量,提高治疗效果的自控激光手术设备。The main purpose of the present invention is to solve the above-mentioned problems in laser surgery medical equipment and laser surgery, to provide a method that can control the elimination of lesion tissue during surgery without damaging normal tissue, has multiple control modes, adjustable parameters, and wide application. It is a self-controlled laser surgery equipment that precisely controls the operation volume and improves the treatment effect.
本发明解决其技术问题所采用的技术方案是:The technical solution adopted by the present invention to solve its technical problems is:
由主控制器、显示器、CCD摄像头、激光器、光源设备、主支架、悬臂、悬挂手术治疗头、显微观察系统和显微手术适配器组成。It consists of a main controller, a display, a CCD camera, a laser, a light source device, a main bracket, a cantilever, a suspended surgical treatment head, a microscopic observation system and a microsurgical adapter.
本发明主要由主控制器、显示器、CCD摄像头、激光器、光源设备、主支架、悬臂、悬挂手术治疗头、显微观察系统、显微手术适配器、图像采集卡、激光器与微机的接口电路、脉冲CO2激光器、指示光激光器、微机和软件系统等几部分组成。本发明治疗眼科的青光眼、老花眼和近视眼等眼科疾病,以及鼻息肉和喉癌等疾病。The present invention mainly consists of a main controller, a display, a CCD camera, a laser, a light source device, a main bracket, a cantilever, a suspending surgical treatment head, a microscopic observation system, a microsurgical adapter, an image acquisition card, an interface circuit between a laser and a microcomputer, a pulse CO 2 laser, pointing light laser, microcomputer and software system are composed of several parts. The invention treats eye diseases such as glaucoma, presbyopia and myopia, as well as diseases such as nasal polyps and laryngeal cancer.
CCD摄像头的摄像输出端通过线路与主控制器相连接,激光器的激光控制连接端口通过线路与主控制器相连接,激光器的激光输出端口通过光导纤维与显微手术适配器的适配器输入端口相连接,CCD摄像头采集病灶组织和正常组织的图像和光谱并通过摄像输出端传输给主控制器。The camera output end of the CCD camera is connected with the main controller through the line, the laser control connection port of the laser is connected with the main controller through the line, the laser output port of the laser is connected with the adapter input port of the microsurgical adapter through the optical fiber, The CCD camera collects images and spectra of lesion tissue and normal tissue and transmits them to the main controller through the camera output terminal.
主控制器、显示器、CCD摄像头、激光器和显微手术适配器通过线路的连接构成手术设备的系统。主控制器、显示器、CCD摄像头、激光器和显微手术适配器在这个系统中各自起到部件的作用,CCD摄像头实时检测手术部位光强度和颜色的变化,同时记录手术过程,并把病灶组织和正常组织的图像和光谱传输给主控制器,图像和光谱通过主控制器监控处理,精确控制手术过程,并能够通过I/O接口控制激光器的开启与关断。本发明采用图像采集卡直接以CCD摄像装置的视频信号为输入,无需信号预处理;模拟信号经A/D转换后直接经PCI总线与主控制器通讯;软件系统控制CCD摄像装置获取所需的手术前后手术部位的图像和光谱,并对图像资料和光谱资料进行存储、转换、分析。主控制器可采用PC计算机。The main controller, monitor, CCD camera, laser and microsurgical adapter are connected by lines to form a system of surgical equipment. The main controller, display, CCD camera, laser and microsurgical adapter each play the role of components in this system. The CCD camera detects the changes in the light intensity and color of the surgical site in real time, records the surgical process, and compares the lesion tissue with the normal one. The image and spectrum of the tissue are transmitted to the main controller. The image and spectrum are monitored and processed by the main controller to precisely control the surgical process, and the laser can be turned on and off through the I/O interface. The present invention adopts the image acquisition card to directly take the video signal of the CCD imaging device as input without signal preprocessing; the analog signal is directly communicated with the main controller through the PCI bus after A/D conversion; the software system controls the CCD imaging device to obtain the required Images and spectra of the surgical site before and after surgery, and store, convert, and analyze the image data and spectral data. The main controller can adopt PC computer.
主控制器识别和处理CCD摄像头采集的病灶组织和正常组织的图像和光谱,并相应地发出指令控制激光器的操作,避免激光手术的误操作损伤正常组织导致手术的失误。The main controller identifies and processes the image and spectrum of the lesion tissue and normal tissue collected by the CCD camera, and sends out instructions to control the operation of the laser accordingly, so as to avoid the misoperation of laser surgery from damaging the normal tissue and causing surgery mistakes.
本发明的主控制器对CCD摄像头采集的病灶组织和正常组织的图像和光谱进行识别和处理,在治疗青光眼时面阵CCD实时监测激光打孔部位组织的光反射强度和颜色的变化,当孔切穿时必伴有光强和颜色的突变,随时检测到这一突变并及时控制激光器关断,这个过程可控制在一个激光脉冲的限度内,从而能有效、可靠地防止激光的过度伤害。在治疗老花眼时实时监控晶体表面的弧度(即屈光度)以及前腔距的改变,及时控制激光能量、光斑大小和巩膜切除图形,提高老花眼的治疗效果。The main controller of the present invention recognizes and processes the image and spectrum of the lesion tissue and normal tissue collected by the CCD camera, and when treating glaucoma, the area array CCD monitors the light reflection intensity and color changes of the tissue at the laser perforated part in real time. Cutting must be accompanied by sudden changes in light intensity and color. Detect this sudden change at any time and control the laser to turn off in time. This process can be controlled within the limit of one laser pulse, so that excessive laser damage can be effectively and reliably prevented. During the treatment of presbyopia, real-time monitoring of the curvature of the crystal surface (that is, diopter) and changes in the anterior cavity distance, timely control of laser energy, spot size and scleral resection pattern, to improve the treatment effect of presbyopia.
显示器与主控制器的显示器连接端口相连接,采用显示屏或触摸屏作为主控制器的显示器,显示器即时显示CCD摄像头所采集的病灶组织和正常组织的图像和光谱,同时显示器上显示手术参数。The display is connected to the display connection port of the main controller, and the display or touch screen is used as the display of the main controller. The display immediately displays the images and spectra of the lesion tissue and normal tissue collected by the CCD camera, and the operation parameters are displayed on the display at the same time.
本发明显示器可采用显示屏或者触摸屏,采用触摸屏可简化计算机,直接在触摸屏上操作修正参数;显示器实时显示CCD摄像头采集的图像和光谱,同时显示手术参数和主控制器发出的操作指令,便于医生观察和治疗。显示器上充分显示出病灶组织和正常组织的图像和光谱、激光输出光的能量、手术参数、光斑的大小以及病灶组织切除的图形。The display of the present invention can use a display screen or a touch screen, and the use of the touch screen can simplify the computer, and directly operate the correction parameters on the touch screen; the display can display the images and spectra collected by the CCD camera in real time, and at the same time display the operation parameters and the operation instructions issued by the main controller, which is convenient for doctors Observation and treatment. The image and spectrum of the lesion tissue and normal tissue, the energy of the laser output light, the operation parameters, the size of the light spot and the graph of lesion tissue resection are fully displayed on the monitor.
激光器的激光输出端口通过光导纤维或导光臂与显微手术适配器的适配器输入端口相连接,传输治疗用激光,治疗用激光器采用脉冲式工作方式的气体激光器或固体激光器或半导体激光器或光纤激光器,脉冲宽度:250μs~100ms,能量密度:5~20J/cm2,脉冲频率:<200Hz。The laser output port of the laser is connected to the adapter input port of the microsurgical adapter through an optical fiber or a light guide arm to transmit laser light for treatment. The laser for treatment is a gas laser or a solid laser or a semiconductor laser or a fiber laser in a pulsed working mode. Pulse width: 250μs~100ms, energy density: 5~20J/cm 2 , pulse frequency: <200Hz.
激光参数的选择对手术的效果有直接的影响,本发明泛指所有能对手术造成影响的激光参数,包括激光波长、输出方式(脉冲,连续)、脉冲能量密度、脉冲宽度、脉冲频率、激光控制方式(人工控制,反馈控制)等。The selection of laser parameters has a direct impact on the effect of surgery. The present invention generally refers to all laser parameters that can affect surgery, including laser wavelength, output mode (pulse, continuous), pulse energy density, pulse width, pulse frequency, laser Control methods (manual control, feedback control), etc.
在经外路激光巩膜切除术中,激光参数的选择应遵循三个原则:热损伤和机械损伤最小;可精确控制手术量;切除效率高、手术时间少。获得最小的热损伤是至关重要的原则,因为无论从对邻近组织的损害来讲,还是对手术后的伤口愈合以及减少瘢痕都是十分关键的。在此前提下,应精确地控制手术量,避免对深部组织的过伤害。只有在满足了上述两条的情况下,才能考虑提高切除效率,减少手术时间。In external laser sclerectomy, the selection of laser parameters should follow three principles: minimal thermal and mechanical damage; precise control of surgical volume; high resection efficiency and less operation time. Obtaining minimal thermal damage is a crucial principle, as it is critical for postoperative wound healing and scar reduction, both in terms of damage to adjacent tissues. Under this premise, the operation volume should be precisely controlled to avoid excessive damage to deep tissues. Only when the above two conditions are met, can we consider improving the resection efficiency and reducing the operation time.
短脉冲输出的中远红外激光以其热效应作用表浅、损伤小、手术出血少等优点,适用于青光眼滤过手术。其中CO2激光在切除组织时具有很强的止血功能,而且切除时对周围组织损伤很小,适于做外路激光切除手术。连续波CO2激光和脉冲与眼组织作用的效果有所不同,使用短脉冲激光限制热扩散是减少热损伤的一种方法。The mid-to-far infrared laser with short pulse output is suitable for glaucoma filtration surgery due to its superficial thermal effect, less damage, and less surgical bleeding. Among them, CO 2 laser has a strong hemostatic function when removing tissue, and it causes little damage to surrounding tissues during removal, so it is suitable for external laser resection. CW CO2 lasers and pulsed lasers interact with ocular tissue differently, and using short pulsed lasers to limit thermal diffusion is one way to reduce thermal damage.
激光器的激光控制连接端口通过线路与主控制器的控制激光器连接端口相连接,主控制器发出指令控制激光器的开机、关机以及修正激光输出量。The laser control connection port of the laser is connected with the control laser connection port of the main controller through a line, and the main controller sends instructions to control the start-up and shutdown of the laser and correct the laser output.
本发明通过主控制器控制激光器的输出方式,包括连续波、单脉冲、多脉冲、复合脉冲等;主控制器可以预先设定也可以在手术中跟据需要随时更改手术参数,手术参数包括:连续波输出的功率、照射时间,脉冲波输出能量、脉宽和频率等。本发明利用高速I/O接口电路,将主控制器跟激光器连接起来,使用D/A转换完成设置参数和控制激光开关的功能,A/D转换可以实时监测激光器的状态,记录激光器实际脉冲总个数以及总作用的时间。The present invention controls the output mode of the laser through the main controller, including continuous wave, single pulse, multi-pulse, compound pulse, etc.; the main controller can be preset or can be changed at any time according to the needs during the operation. The operation parameters include: Continuous wave output power, irradiation time, pulse wave output energy, pulse width and frequency, etc. The present invention uses a high-speed I/O interface circuit to connect the main controller with the laser, and uses D/A conversion to complete the functions of setting parameters and controlling the laser switch. The A/D conversion can monitor the state of the laser in real time and record the actual pulse total of the laser. number and total duration of action.
主支架的上部设置悬臂,悬臂的一端部设置悬挂手术治疗头,主支架和悬臂支撑悬吊悬挂手术治疗头,悬挂手术治疗头在悬臂的端部保持治疗状态或自由移动。The upper part of the main bracket is provided with a cantilever, and one end of the cantilever is provided with a suspended surgical treatment head, the main support and the cantilever support the suspended suspended surgical treatment head, and the suspended surgical treatment head maintains a treatment state or moves freely at the end of the cantilever.
悬挂手术治疗头悬吊在主支架的悬臂上,主支架和悬臂不仅保持悬挂和支撑悬挂手术治疗头处于最佳治疗位置,还能够在手术中上、下、左、右、前、后自由移动,使得悬挂手术治疗头始终处于最佳治疗状态。The suspended surgical treatment head is suspended on the cantilever of the main bracket. The main bracket and the cantilever not only keep the suspension and support the suspended surgical treatment head in the best treatment position, but also can move freely up, down, left, right, front and back during the operation , so that the hanging surgical treatment head is always in the best treatment state.
悬挂手术治疗头的上部设置显微观察系统和显微观察镜,悬挂手术治疗头的一侧设置CCD摄像头,CCD摄像头的摄像输出端通过线路与主控制器的数据信息接口相连接,即时把捕获到的图像和光谱传输给主控制器。A microscopic observation system and a microscopic observation mirror are installed on the upper part of the suspended surgical treatment head, and a CCD camera is installed on one side of the suspended surgical treatment head. The received images and spectra are transmitted to the main controller.
悬挂手术治疗头的下部设置显微手术适配器,显微手术适配器的适配器输入端口与激光器相连接,悬挂手术治疗头的一侧设置光源接口,光源设备的光源输出端通过光源接口接通光源照明手术部位。The lower part of the suspended surgical treatment head is provided with a microsurgery adapter, the adapter input port of the microsurgery adapter is connected to the laser, and one side of the suspended surgical treatment head is provided with a light source interface, and the light source output end of the light source device is connected to the light source through the light source interface for lighting operations. parts.
在悬挂手术治疗头上放置显微观察系统、显微观察镜、显微手术适配器和CCD摄像头,激光器、光源设备以及主控制器均通过线路分别向连接,悬挂手术治疗头成为治疗的中心。The microscopic observation system, microscopic observation mirror, microsurgical adapter and CCD camera are placed on the suspended surgical treatment head. The laser, light source equipment and main controller are all connected to each other through lines, and the suspended surgical treatment head becomes the center of treatment.
在悬挂手术治疗头内设置光学镜片组,光学镜片组形成光路,通过光学镜片组将显微观察系统、显微观察镜、CCD摄像头和显微手术适配器构成一整体。An optical lens group is arranged in the suspension operation treatment head, the optical lens group forms an optical path, and a microscopic observation system, a microscopic observation mirror, a CCD camera and a microsurgical adapter are formed as a whole through the optical lens group.
设置在悬挂手术治疗头上的显微观察系统、显微观察镜、CCD摄像头和显微手术适配器通过光学镜片组有机的连成一个整体,显微观察系统、显微观察镜、CCD摄像头和显微手术适配器各自在光学镜片组相应的位置。The micro-observation system, micro-observation mirror, CCD camera and micro-surgical adapter set on the suspended surgical treatment head are organically connected as a whole through the optical lens group. The micro-observation system, micro-observation mirror, CCD camera and microscope The microsurgical adapters are respectively in the corresponding positions of the optical lens group.
脚踏开关与主控制器相连接,启闭脚踏开关通过主控制器手动控制激光器的启动和关闭,当手术中出现突发变故关闭脚踏开关即刻关闭激光器,突发变故结束开启脚踏开关,恢复工作状态。The foot switch is connected to the main controller, and the on-off foot switch manually controls the start and stop of the laser through the main controller. When a sudden change occurs during the operation, turn off the foot switch to immediately turn off the laser, and turn on the foot switch when the sudden change is over. , resume working status.
脚踏开关的操作是人工控制的,是由医生视手术情况,做出主观判断后关断激光器,当需要继续操作,打开脚踏开关恢复工作状态。另外,关断激光器还有两种方式,一种是主控制器上“手术结束”按钮,是由操作人员控制,是为了应付紧急情况保护人身安全而增加的防范措施;另一种是依据病灶组织和正常组织的图像和光谱--阈值控制,属于自动控制的方式。这三项措施中任何1项起作用时,都会关断激光器,而且这三项措施互相不冲突,因而增加了整体系统的安全性。The operation of the foot switch is manually controlled, and the doctor turns off the laser after making a subjective judgment according to the operation situation. When it is necessary to continue the operation, turn on the foot switch to resume the working state. In addition, there are two ways to turn off the laser. One is the "operation end" button on the main controller, which is controlled by the operator and is an added precautionary measure to protect personal safety in case of emergency; Image and spectrum of tissue and normal tissue-threshold control, which belongs to the automatic control method. When any one of these three measures is active, the laser will be turned off, and these three measures do not conflict with each other, thus increasing the safety of the overall system.
由主控制器、显示器、图像采集头、激光器、光源设备和内窥镜组成,显示器与主控制器的显示器连接端口相连接,采用通用显示器或触摸屏显示器作为主控制器的显示器,显示器即时显示CCD摄像头所采集的病灶组织和正常组织的图像和光谱,同时显示器上显示手术参数。It is composed of a main controller, a display, an image acquisition head, a laser, a light source device and an endoscope. The display is connected to the display connection port of the main controller. A general-purpose display or a touch screen display is used as the display of the main controller. The display immediately displays the CCD The image and spectrum of the lesion tissue and normal tissue collected by the camera, and the surgical parameters are displayed on the monitor.
本发明主要由主控制器、显示器、CCD摄像头、激光器、光源设备、主支架、悬臂、悬挂手术治疗头、显微观察系统、显微手术适配器、图像采集卡、激光器与微机的接口电路、脉冲激光器、指示光激光器、微机和软件系统等几部分组成。显示器实时显示CCD摄像头采集的图像和光谱,同时显示手术参数和主控制器发出的操作指令,便于医生观察和治疗。显示器上充分显示出病灶组织和正常组织的图像和光谱、激光输出光的能量、手术参数、光斑的大小以及病灶组织切除的图形。本发明治疗食道癌、胃癌以及直肠息肉的疾病。The present invention mainly consists of a main controller, a display, a CCD camera, a laser, a light source device, a main bracket, a cantilever, a suspending surgical treatment head, a microscopic observation system, a microsurgical adapter, an image acquisition card, an interface circuit between a laser and a microcomputer, a pulse It is composed of several parts such as laser, pointing light laser, microcomputer and software system. The monitor displays the images and spectra collected by the CCD camera in real time, as well as the operation parameters and the operation instructions issued by the main controller, which is convenient for doctors to observe and treat. The image and spectrum of the lesion tissue and normal tissue, the energy of the laser output light, the operation parameters, the size of the light spot and the graph of lesion tissue resection are fully displayed on the monitor. The invention treats diseases of esophageal cancer, gastric cancer and rectal polyps.
内窥镜的上部设置活检口、气孔、水孔、光源接口和内窥镜数据端口,活检口、气孔、水孔和光源接口由内窥镜的上部贯通至观测治疗端部,在观测治疗端部构成活检口端口、气孔端口、水孔端口和光源头,被手术病灶组织汽化后产生的废气通过气孔端口由气孔排出,手术过程中被手术部位产生的组织液体及水分通过水孔端口由水孔排出,光源设备的光源输出端口通过内窥镜的光源接口由光纤束传输到观测治疗端口的光源头,观测治疗端口上至少设置3个光源头,光源头照明手术的部位。The upper part of the endoscope is provided with a biopsy port, air hole, water hole, light source interface and endoscope data port. The biopsy port, air hole, water hole and light source interface are connected from the upper part of the endoscope to the observation and treatment end. The part constitutes the biopsy port, the stomata port, the water hole port and the light source head. The waste gas generated after being vaporized by the surgical lesion tissue is discharged through the stomata port. Exhaust, the light source output port of the light source device is transmitted to the light source head of the observation and treatment port by the fiber bundle through the light source interface of the endoscope. At least 3 light source heads are arranged on the observation and treatment port, and the light source head illuminates the surgical site.
在内窥镜的观测治疗端部设置CCD摄像头的图形采集头,内窥镜上部设置的内窥镜数据端口通过线路与主控制器的数据信息接口相连接并与主控制器的图像卡相连接,CCD摄像头的图形采集头采集病灶组织和正常组织的图像和光谱,主控制器识别和处理CCD摄像头采集的病灶组织和正常组织的图像和光谱,并相应地发出指令控制激光器的操作,避免激光手术的误操作损伤正常组织导致手术的失误。The image acquisition head of the CCD camera is set at the observation and treatment end of the endoscope, and the endoscope data port set on the upper part of the endoscope is connected to the data information interface of the main controller through a line and connected to the image card of the main controller , the image acquisition head of the CCD camera collects images and spectra of the lesion tissue and normal tissue, and the main controller recognizes and processes the images and spectra of the lesion tissue and normal tissue collected by the CCD camera, and issues instructions accordingly to control the operation of the laser to avoid laser Surgical misoperation damages normal tissue and leads to surgical errors.
激光器的激光输出端口连接光导纤维,把光导纤维从内窥镜的活检口插入,光导纤维的端部直至观测治疗端口处的活检口端口,传输治疗用激光,治疗用激光器采用脉冲式工作方式的气体激光器或固体激光器或半导体激光器或光纤激光器,脉冲宽度:250μs~100ms,能量密度:5~20J/cm2,脉冲频率:<200Hz。The laser output port of the laser is connected to the optical fiber, the optical fiber is inserted from the biopsy port of the endoscope, the end of the optical fiber reaches the biopsy port at the observation treatment port, and the therapeutic laser is transmitted. The therapeutic laser adopts the pulse working mode Gas laser or solid laser or semiconductor laser or fiber laser, pulse width: 250μs-100ms, energy density: 5-20J/cm 2 , pulse frequency: <200Hz.
激光器的激光控制连接端口通过线路与主控制器的控制激光器连接端口相连接,主控制器发出指令控制激光器的开机、关机以及修正激光输出量。The laser control connection port of the laser is connected with the control laser connection port of the main controller through a line, and the main controller sends instructions to control the start-up and shutdown of the laser and correct the laser output.
脚踏开关与主控制器相连接,启闭脚踏开关通过主控制器手动控制激光器的启动和关闭,当手术中出现突发变故关闭脚踏开关即刻关闭激光器,突发变故结束开启脚踏开关,恢复工作状态。The foot switch is connected to the main controller, and the on-off foot switch manually controls the start and stop of the laser through the main controller. When a sudden change occurs during the operation, turn off the foot switch to immediately turn off the laser, and turn on the foot switch when the sudden change is over. , resume working status.
术前准备后,开启主控制器、显示器、CCD摄像头和光源设备,调整主支架上的悬臂和悬挂手术治疗头,治疗端进入手术区域,把悬挂手术治疗头上的显微手术适配器对准手术部位。After the preoperative preparation, turn on the main controller, monitor, CCD camera and light source equipment, adjust the cantilever on the main bracket and suspend the surgical treatment head, the treatment end enters the operation area, and align the microsurgical adapter on the suspended surgical treatment head with the operating area. parts.
本发明主要由主控制器、显示器、CCD摄像头、激光器、光源设备、主支架、悬臂、悬挂手术治疗头、显微观察系统、显微手术适配器、图像采集卡、激光器与微机的接口电路、脉冲激光器、指示光激光器、微机和软件系统等几部分组成。采用Visual C进行编程,系统软件按功能可划分为三个部分-CCD控制及图象处理部分、激光控制部分和病例管理数据库。本发明治疗眼科的青光眼、老花眼以及近视眼等眼科疾病。The present invention mainly consists of a main controller, a display, a CCD camera, a laser, a light source device, a main bracket, a cantilever, a suspending surgical treatment head, a microscopic observation system, a microsurgical adapter, an image acquisition card, an interface circuit between a laser and a microcomputer, a pulse It is composed of several parts such as laser, pointing light laser, microcomputer and software system. Using Visual C for programming, the system software can be divided into three parts according to functions - CCD control and image processing part, laser control part and case management database. The invention treats eye diseases such as glaucoma, presbyopia and myopia in ophthalmology.
通过悬挂手术治疗头上的显微观察系统和显示器显示的图像和光谱,观察手术部位的病灶组织和正常组织,主控制器识别、确认病灶组织和正常组织的图像和光谱,将显微手术适配器锁定病灶组织部位。Through the microscopic observation system and the images and spectra displayed on the display on the suspending surgical treatment head, observe the lesion tissue and normal tissue at the surgical site, the main controller identifies and confirms the image and spectrum of the lesion tissue and normal tissue, and connects the microsurgical adapter Lock the lesion tissue site.
激光手术中,手术量的控制一般为人工控制方式,由医生实时观察激光切除深度,控制方式影响较大,手术量难以精确控制,外路激光巩膜切除术联合虹膜切除术对手术量的控制提出了更高的要求,采用反馈控制方式--面阵CCD实时监测激光打孔部位组织的光反射强度和颜色的变化,具有多种控制方式、参数可调、用于手术的系统。In laser surgery, the operation volume is generally controlled manually, and the doctor observes the depth of laser resection in real time. The control method has a great influence, and it is difficult to accurately control the operation volume. In order to meet higher requirements, the feedback control method-area array CCD is used to monitor the light reflection intensity and color changes of the tissue at the laser perforation site in real time. It has a variety of control methods, adjustable parameters, and a system for surgery.
开启激光器,主控制器修正激光器的手术参数,调整激光器的输出功率,激光器准备开机出光。Turn on the laser, the main controller corrects the surgical parameters of the laser, adjusts the output power of the laser, and the laser is ready to turn on and emit light.
本发明开始工作时,点击“开始手术”按钮,显示器上自动弹出信息框“请选择手术部位”,用鼠标点击图像中的指示光激光点,把该点为中心自动画出一个52×52pixel的方框,表示将取该方框内的像素点作为阈值判断的数据,按“确定”按钮后,等待医生开机的信号。When the present invention starts to work, click the "start operation" button, and the information box "please select the operation site" will pop up automatically on the display, click the pointing light laser point in the image with the mouse, and draw a 52×52 pixel automatically with this point as the center The box indicates that the pixel points in the box will be taken as the data for threshold judgment, and after pressing the "OK" button, wait for the signal of the doctor to turn on the machine.
锁定病灶组织,主控制器发“开机”出操作指令,激光器开机出光,激光器输出治疗激光,激光器的治疗激光切割或汽化手术部位的病灶组织,治疗激光采用脉冲式工作方式的气体激光器或固体激光器或半导体激光器或光纤激光器,脉冲宽度:250μs~100ms,能量密度:5~20J/cm2,脉冲频率:<200Hz。Lock the lesion tissue, the main controller sends out the operation command of "starting up", the laser is turned on and emits light, and the laser outputs therapeutic laser. The laser treatment laser cuts or vaporizes the lesion tissue at the surgical site. Or semiconductor laser or fiber laser, pulse width: 250μs-100ms, energy density: 5-20J/cm 2 , pulse frequency: <200Hz.
CCD摄像头始终把捕获到的图像和光谱反馈给主控制器,显示器始终显示CCD摄像头捕获到的图像和光谱,主控制器随时监控捕获到的图像和光谱的变化,并及时对激光器发出操作指令,停机或开机或修正激光的输出量。The CCD camera always feeds back the captured images and spectra to the main controller, and the monitor always displays the images and spectra captured by the CCD camera. The main controller monitors the changes of the captured images and spectra at any time, and issues operation instructions to the laser in time. Shut down or start up or correct the output of the laser.
激光参数的选择对手术的效果有直接的影响,在经外路激光巩膜切除术中,激光参数的选择应遵循三个原则:热损伤和机械损伤最小;可精确控制手术量;切除效率高、手术时间少。短脉冲输出的中远红外激光以其热效应作用表浅、损伤小、手术出血少等优点,适用于青光眼滤过手术。其中激光在切除组织时具有很强的止血功能,而且切除时对周围组织损伤很小,适于做外路激光切除手术。连续波激光和脉冲与眼组织作用的效果有所不同,使用短脉冲激光限制热扩散是减少热损伤的一种方法。The selection of laser parameters has a direct impact on the effect of the operation. In laser sclerectomy through the external route, the selection of laser parameters should follow three principles: minimal thermal and mechanical damage; precise control of surgical volume; high resection efficiency, The operation time is less. The mid-to-far infrared laser with short pulse output is suitable for glaucoma filtration surgery due to its superficial thermal effect, less damage, and less surgical bleeding. Among them, the laser has a strong hemostatic function when removing tissue, and the damage to the surrounding tissue is small during the removal, so it is suitable for external laser resection. Continuous wave lasers and pulsed lasers interact with eye tissue differently, and using short pulsed lasers to limit thermal diffusion is one way to reduce thermal damage.
脚踏开关与主控制器相连接,启闭脚踏开关通过主控制器控制激光器的开机和关机。The foot switch is connected with the main controller, and the on-off foot switch controls the laser on and off through the main controller.
脚踏开关的操作是人工控制的,是由医生视手术情况,做出主观判断后关断激光器,当需要继续操作,打开脚踏开关恢复工作状态。The operation of the foot switch is manually controlled, and the doctor turns off the laser after making a subjective judgment according to the operation situation. When it is necessary to continue the operation, turn on the foot switch to resume the working state.
当病灶组织的图像和光谱一消失,CCD摄像头将捕获到正常组织的图像和光谱反馈给主控制器,主控制器监控到正常组织的图像和光谱出现,即时对激光器发出“停机”操作的指令,激光器接到“停机”操作指令,在发出下一个脉冲激光前停止输出激光,不损伤正常组织。When the image and spectrum of the lesion tissue disappear, the CCD camera will capture the image and spectrum of the normal tissue and feed it back to the main controller. The main controller monitors the appearance of the image and spectrum of the normal tissue, and immediately issues a "stop" operation command to the laser , the laser receives the "shutdown" operation command, and stops outputting laser light before sending out the next pulse laser, without damaging normal tissues.
本发明主控制器可以预先设定也可以在手术中跟据需要随时更改手术参数,手术参数包括:连续波输出的功率、照射时间,脉冲波输出能量、脉宽和频率等。本发明可以实时监测激光器的状态,记录激光器实际脉冲总个数以及总作用的时间。The main controller of the present invention can be preset or can be changed at any time according to the needs during the operation. The operation parameters include: continuous wave output power, irradiation time, pulse wave output energy, pulse width and frequency, etc. The invention can monitor the state of the laser in real time, and record the total number of actual pulses and the total action time of the laser.
调整主支架上的悬臂和悬挂手术治疗头,寻找手术部位的病灶组织,把悬挂手术治疗头上的显微手术适配器对准手术部位的病灶组织,主控制器识别、确认病灶组织和正常组织的图像和光谱,锁定病灶组织,主控制器发出操作指令,激光器开机出光,激光器输出治疗激光,激光器的治疗激光切割或汽化手术部位的病灶组织,往复循环,直至完全消除手术部位的病灶组织。Adjust the cantilever on the main bracket and the suspending surgical treatment head to find the lesion tissue at the surgical site, align the microsurgical adapter on the suspending surgical treatment head with the lesion tissue at the surgical site, and the main controller identifies and confirms the difference between the lesion tissue and the normal tissue. The image and spectrum lock the lesion tissue, the main controller issues an operation command, the laser turns on and emits light, the laser outputs a therapeutic laser, the therapeutic laser cuts or vaporizes the lesion tissue at the surgical site, and reciprocates until the lesion tissue at the surgical site is completely eliminated.
当手术部位的病灶组织消除了一部分,再继续治疗另外部分的病灶组织,调整悬挂手术治疗头的治疗位置,锁定后继续治疗,直到病灶组织完全消除,手术结束。When a part of the lesion tissue at the surgical site is eliminated, continue to treat the other part of the lesion tissue, adjust the treatment position of the suspended surgical treatment head, lock it and continue the treatment until the lesion tissue is completely eliminated, and the operation is over.
当完全消除手术部位的病灶组织,关闭激光器停止输出治疗激光;通过悬挂手术治疗头上的显微观察系统和显示器显示的图像观察手术部位的正常组织和病灶组织,主控制器确认手术部位完全消除病灶组织后,移动主支架上的悬臂和悬挂手术治疗头,把悬挂手术治疗头上的显微手术适配器从手术部位移开。When the lesion tissue at the surgical site is completely eliminated, turn off the laser and stop outputting the therapeutic laser; observe the normal tissue and lesion tissue at the surgical site through the microscopic observation system on the suspending surgical treatment head and the image displayed on the monitor, and the main controller confirms that the surgical site is completely eliminated After the lesion is organized, move the cantilever on the main frame and the suspending surgical treatment head, and move the microsurgical adapter on the suspending surgical treatment head away from the operation site.
关闭主控制器、显示器、CCD摄像头和光源,手术结束。Turn off the main controller, monitor, CCD camera and light source, and the operation is over.
脚踏开关与主控制器相连接,当手术中出现突发变故,关闭脚踏开关,脚踏开关通过主控制器关闭激光器,激光器即刻停机,停止输出治疗激光;The foot switch is connected to the main controller. When there is a sudden change in the operation, the foot switch is turned off, and the foot switch turns off the laser through the main controller. The laser stops immediately and stops outputting therapeutic laser;
当突发变故结束,开启脚踏开关,激光器恢复工作状态。When the accident is over, turn on the foot switch, and the laser will resume working.
一旦出现突发变故,主控制器没有发出关闭激光器的操作指令,手术尚未结束,医生可以采用脚踏开关,脚踏开关的操作是人工控制的,是由医生视手术情况,做出主观判断后关断激光器;当突发变故消除需要继续操作,打开脚踏开关恢复工作状态。Once a sudden change occurs, the main controller does not issue an operation command to turn off the laser, and the operation is not over yet, the doctor can use the foot switch, the operation of the foot switch is controlled manually, and the doctor makes a subjective judgment based on the operation situation. Turn off the laser; when the sudden change eliminates the need to continue the operation, turn on the foot switch to resume the working state.
术前准备后,开启主控制器、显示器、光源设备和CCD摄像头,开启光源设备观测治疗端口的光源头照明手术的部位,内窥镜的观测治疗端部进入手术区域,对准手术部位。After preoperative preparation, turn on the main controller, display, light source equipment and CCD camera, turn on the light source equipment to observe the light source head of the treatment port to illuminate the surgical site, and the observation and treatment end of the endoscope enters the surgical area and aligns with the surgical site.
本发明主要由主控制器、激光器、显示器、内窥镜光源、内窥镜以及脚踏开关组成,激光器跟主控制器的连接是通过A/D卡和数据线连接,主控制器跟显示器的连接是通过显示适配器信号线连接,主控制器跟内窥镜的连接是通过一组数据线连接,光源设备跟内窥镜的连接是通过线路跟内窥镜的光源接口相连接。本发明治疗鼻息肉、喉癌、食道癌、胃癌以及直肠息肉的疾病。The present invention is mainly made up of main controller, laser device, display, endoscope light source, endoscope and foot switch, the connection of laser device and main controller is to connect through A/D card and data line, the connection between main controller and display The connection is through the signal line of the display adapter, the connection between the main controller and the endoscope is through a set of data lines, and the connection between the light source device and the endoscope is through the line to connect with the light source interface of the endoscope. The invention treats the diseases of nasal polyps, laryngeal cancer, esophageal cancer, gastric cancer and rectal polyps.
激光器的激光输出端口连接光导纤维,把光导纤维从内窥镜的活检口插入,光导纤维的端部直至观测治疗端口处的活检口端口,在观测治疗端口处出光治疗病灶。The laser output port of the laser is connected to the optical fiber, the optical fiber is inserted from the biopsy port of the endoscope, the end of the optical fiber reaches the biopsy port at the observation and treatment port, and light is emitted from the observation and treatment port to treat the lesion.
将内窥镜的观测治疗端口对准手术部位,通过显示器显示手术部位的图像和光谱,观察手术部位的病灶组织和正常组织,主控制器识别、确认病灶组织和正常组织的图像和光谱。Aim the observation and treatment port of the endoscope at the surgical site, display the image and spectrum of the surgical site on the monitor, observe the lesion tissue and normal tissue at the surgical site, and the main controller identifies and confirms the image and spectrum of the lesion tissue and normal tissue.
通过主控制器修正手术参数,调整激光器的输出功率,激光器准备开机出光。Correct the surgical parameters through the main controller, adjust the output power of the laser, and the laser is ready to start and emit light.
锁定病灶组织,主控制器发出操作指令,激光器开机出光,激光器输出治疗激光,激光器的治疗激光切割或汽化手术部位的病灶组织,治疗用激光器采用脉冲式工作方式的气体激光器或固体激光器或半导体激光器或光纤激光器,脉冲宽度:250μs~100ms,能量密度:5~20J/cm2,脉冲频率:<200Hz。Lock the lesion tissue, the main controller sends out operation instructions, the laser is turned on and emits light, the laser outputs therapeutic laser, the therapeutic laser cuts or vaporizes the lesion tissue at the surgical site, and the therapeutic laser adopts a gas laser or a solid laser or a semiconductor laser in a pulsed working mode. Or fiber laser, pulse width: 250μs-100ms, energy density: 5-20J/cm 2 , pulse frequency: <200Hz.
CCD摄像头始终把捕获到的图像和光谱反馈给主控制器,显示器始终显示CCD摄像头捕获到的图像和光谱,主控制器随时监控捕获到的图像和光谱的变化,并及时对激光器发出操作指令,停机或开机或修正激光的输出量。The CCD camera always feeds back the captured images and spectra to the main controller, and the monitor always displays the images and spectra captured by the CCD camera. The main controller monitors the changes of the captured images and spectra at any time, and issues operation instructions to the laser in time. Shut down or start up or correct the output of the laser.
在手术过程中被手术的病灶组织汽化后产生的废气通过气孔端口由气孔排出,手术过程中被手术的部位产生的组织液体及水分通过水孔端口由水孔排出。During the operation, the waste gas produced by the vaporization of the operated lesion tissue is discharged from the stomata through the stomata port, and the tissue fluid and moisture generated in the operated part during the operation are discharged from the water hole through the water hole port.
当病灶组织的图像和光谱一消失,CCD摄像头将捕获到正常组织的图像和光谱反馈给主控制器,主控制器监控到正常组织的图像和光谱出现,即时对激光器发出“停机”操作的指令,激光器接到“停机”操作指令,在发出下一个脉冲激光前停止输出激光,不损伤正常组织。When the image and spectrum of the lesion tissue disappear, the CCD camera will capture the image and spectrum of the normal tissue and feed it back to the main controller. The main controller monitors the appearance of the image and spectrum of the normal tissue, and immediately issues a "stop" operation command to the laser , the laser receives the "shutdown" operation command, and stops outputting laser light before sending out the next pulse laser, without damaging normal tissues.
调整内窥镜的观测治疗端口,寻找手术部位的病灶组织,将内窥镜的观测治疗端口对准手术部位的病灶组织,主控制器识别、确认病灶组织和正常组织的图像和光谱,锁定病灶组织,主控制器发出操作指令,激光器开机出光,激光器输出治疗激光,激光器的治疗激光切割或汽化手术部位的病灶组织,往复循环,直至完全消除手术部位的病灶组织。Adjust the observation and treatment port of the endoscope to find the lesion tissue at the surgical site, align the observation and treatment port of the endoscope with the lesion tissue at the surgical site, the main controller identifies and confirms the images and spectra of the lesion tissue and normal tissue, and locks the lesion Tissue, the main controller sends out operation instructions, the laser is turned on to emit light, the laser outputs therapeutic laser, the therapeutic laser cuts or vaporizes the lesion tissue at the surgical site, and reciprocates until the lesion tissue at the surgical site is completely eliminated.
当完全消除手术部位的病灶组织,关闭激光器停止输出治疗激光。When the lesion tissue at the surgical site is completely eliminated, turn off the laser and stop outputting the therapeutic laser.
通过显示器显示的图像观察手术部位的正常组织和病灶组织,主控制器确认手术部位完全消除病灶组织后,内窥镜的观测治疗端口退出手术部位,关闭主控制器、显示器、CCD摄像头和光源设备,手术结束。Observe the normal tissue and lesion tissue of the surgical site through the image displayed on the monitor. After the main controller confirms that the surgical site has completely eliminated the lesion tissue, the observation and treatment port of the endoscope exits the surgical site, and the main controller, monitor, CCD camera and light source equipment are turned off. , the operation is over.
脚踏开关与主控制器相连接,当手术中出现突发变故,关闭脚踏开关,脚踏开关通过主控制器关闭激光器,激光器即刻停机,停止输出治疗激光。The foot switch is connected with the main controller. When there is a sudden change in the operation, the foot switch is turned off, and the foot switch turns off the laser through the main controller. The laser stops immediately and stops outputting therapeutic laser light.
当突发变故结束,开启脚踏开关,激光器恢复工作状态。When the accident is over, turn on the foot switch, and the laser will resume working.
本发明为探讨激光手术的可行性及效果,并与传统的小梁切除术对比,实施了动物实验。In order to explore the feasibility and effect of laser surgery, and compare it with traditional trabeculectomy, the present invention implements animal experiments.
实验材料Experimental Materials
1、动物:由天津医科大学实验动物中心提供的日本大耳白兔种的健康成年白兔30只,体重为1.8~2.9公斤。雌雄各半,分笼喂养。1. Animals: 30 healthy adult white rabbits of the Japanese big-eared white rabbit species provided by the Experimental Animal Center of Tianjin Medical University, weighing 1.8-2.9 kg. Male and female are half and half, and they are fed in separate cages.
2、激光器:激光手术仪器2. Laser: laser surgery instrument
3、眼压计:Perkins压平眼压计3. Tonometer: Perkins applanation tonometer
4、眼科显微手术放大镜和手术器械4. Ophthalmic Microsurgery Magnifiers and Surgical Instruments
实验方法experimental method
1、将30只白兔按左右眼分成两组,右眼为实验组,用CO2激光手术系统进行激光巩膜切除术联合虹膜切除术;左眼为对照组,进行传统的小梁切除术。此前已作双眼术前眼压的测量,经统计学检验无显著差异。1.
2、术后三天0.25%氯霉素眼药水和0.5%可的松眼药水点双眼,3次/日。收集记录术前、术后第1、2、3、7、14、28天的眼压、滤过泡、角膜、前房、虹膜和晶体的情况。2. Apply 0.25% chloramphenicol eye drops and 0.5% cortisone eye drops to both eyes three days after operation, 3 times a day. The intraocular pressure, filtering bleb, cornea, anterior chamber, iris and lens were collected and recorded before operation and on the 1st, 2nd, 3rd, 7th, 14th, and 28th day after operation.
实验结果Experimental results
1、眼前节检查:1. Anterior segment inspection:
实验组的前房反应轻微,且术后3天前房反应完全消失,而对照组经过28天才完全恢复,说明传统手术对前房的影响远大于激光手术对前房的影响,而且前房恢复慢。The anterior chamber reaction in the experimental group was mild, and the anterior chamber reaction completely disappeared 3 days after the operation, while the control group recovered completely after 28 days, indicating that the impact of traditional surgery on the anterior chamber is far greater than that of laser surgery on the anterior chamber, and the anterior chamber recovery slow.
2、滤过泡分析2. Filter bleb analysis
将实验组与对照组术后各级滤过泡的眼数分布情况作秩和检验,术后3天和术后28天的比较结果,P<0.01,差异有统计学意义,实验组明显优于对照组;术后7天的比较结果,P<0.05,差异有统计学意义,实验组优于对照组;术后14天的比较结果,P>0.05,统计学上无显著差异。这表明实验组和对照组的滤过泡功能在大部分时间里有显著性差异,实验组优于对照组。The postoperative distribution of the number of filtering blebs at various levels in the experimental group and the control group was tested by a rank sum test. The comparison results of postoperative 3 days and postoperative 28 days, P<0.01, the difference was statistically significant, and the experimental group was obviously superior. Compared with the control group; the comparison result of 7 days after operation, P<0.05, the difference is statistically significant, the experimental group is better than the control group; the comparison result of 14 days after operation, P>0.05, there is no statistically significant difference. This indicated that the filtering bleb function of the experimental group and the control group had significant differences most of the time, and the experimental group was better than the control group.
3、眼压的变化3. Changes in intraocular pressure
术后1天、2天、3天、7天的两组比较的结果,P<0.01,有显著性差异。在此期间,对照组眼压平均值小于实验组。术后14天的比较结果,P>0.05,无显著差异。而到了第28天,实验组的眼压平均值小于对照组(P<0.01)。也就是说在术后较短的时间里,对照组的眼压平均值小于实验组,而后两组眼压平均值趋于相同,到28天时实验组眼压平均值小于对照组。The results of comparison between the two groups at 1 day, 2 days, 3 days, and 7 days after operation, P<0.01, have significant differences. During this period, the average intraocular pressure of the control group was lower than that of the experimental group. 14 days after the comparison of the results, P> 0.05, no significant difference. On the 28th day, the average intraocular pressure of the experimental group was lower than that of the control group (P<0.01). That is to say, in a short period of time after the operation, the average intraocular pressure of the control group was lower than that of the experimental group, and then the average intraocular pressure of the two groups tended to be the same. By 28 days, the average intraocular pressure of the experimental group was lower than that of the control group.
实验结果表明,与传统的机械性小梁切除术相比,激光巩膜切除术联合虹膜切除术有明显的优势:手术方法简单、易于控制手术,手术时间短;精确控制手术量,满足手术的要求;前房反应轻,无1例出血;形成较好的功能性滤过泡;眼压下降平稳、持久;孔道规则、上皮组织被覆完整、孔道愈合较好;孔周围组织炎反应和纤维化程度较轻。The experimental results show that compared with the traditional mechanical trabeculectomy, laser sclerectomy combined with iridectomy has obvious advantages: the operation method is simple, easy to control the operation, and the operation time is short; the operation volume can be precisely controlled to meet the operation requirements ; Mild anterior chamber reaction, no hemorrhage; good functional filtering bleb formed; stable and long-lasting drop in intraocular pressure; regular pores, complete epithelial tissue covering, and good healing of the pores; tissue inflammation and fibrosis around the pores lighter.
本发明是自控激光手术设备。结构简单,设计合理,制作简单,操作简易容易掌握,手术过程中消除病灶组织的同时不损伤正常组织,具有多种控制方式、参数可调、应用广泛,精确地控制手术量,提高治疗效果,能够广泛的应用于外科、内科、五官科以及眼科疾病的治疗,可实时监视手术过程的、参数可调,可精确地控制手术量并减少对孔周围组织的损伤,手术效果理想。The present invention is a self-controlled laser surgery device. The structure is simple, the design is reasonable, the production is simple, and the operation is simple and easy to master. During the operation, the lesion tissue is eliminated while the normal tissue is not damaged. It has a variety of control methods, adjustable parameters, and wide application. It can precisely control the operation volume and improve the treatment effect. It can be widely used in the treatment of surgery, internal medicine, ENT and ophthalmic diseases. It can monitor the operation process in real time and adjust the parameters. It can accurately control the operation volume and reduce the damage to the tissues around the hole, and the operation effect is ideal.
可以选择多种输出方式,包括连续波、单脉冲、多脉冲、复合脉冲等。连续波输出的功率、照射时间,脉冲波输出能量、脉宽和频率等参数均可预先设定并按需要随时更改;连续激光辐照时间或脉冲激光脉冲总数既可以由人工控制也可以自动反馈控制,并可以在手术结束后立即显示结果;由软件做成的调节旋钮通过接口电路调节激光器的各个参数,与模拟调节相比,具有调整方便、直观、调整量精确、可靠等优点;使用摄像装置实时监视手术过程,可及时检测到滤过孔切穿,反馈控制激光器关断,有效地防止激光的过伤害;可以实时记录手术过程,便于对病人资料进行管理。病历管理数据库系统不但可以将术前和术后的图像资料纪录在案,还可供医生和病人随时查找;根据激光切除滤过术的特点,为避免滤过孔穿透后激光继续对周围特别是深部组织的伤害,采用两种控制方式。一是主动控制方式,二是反馈控制方式。前者是通过对欲切除组织特性的分析,经大量反复实验,总结出最佳的控制参数,通过预先设定的程序,实现自动控制。后一种方式采用摄像装置实时检测切孔部位亮度和颜色的变化。实验发现孔切穿常伴有光强和颜色的突变,及时地检测到这一突变并反馈控制激光器关断,可以有效地防止激光的过伤害;可见光波段的红色激光作指引光,而反馈控制中需要探测孔切穿时光强或颜色的变化,为避免红色指引光对检测的干扰,采用了两种方法:一是选用除红色之外的激光作指引光,二是用主控制器控制适时自动关闭指引光。A variety of output modes can be selected, including continuous wave, single pulse, multi-pulse, composite pulse, etc. Continuous wave output power, irradiation time, pulse wave output energy, pulse width and frequency and other parameters can be preset and changed at any time as needed; continuous laser irradiation time or the total number of pulsed laser pulses can be controlled manually or automatically fed back control, and can display the results immediately after the operation; the adjustment knob made of software adjusts various parameters of the laser through the interface circuit. Compared with analog adjustment, it has the advantages of convenient adjustment, intuitive, accurate adjustment, and reliability; The device monitors the operation process in real time, and can detect the cut-through of the filter hole in time, and feedback controls the laser to turn off, effectively preventing the laser from over-injury; it can record the operation process in real time to facilitate the management of patient data. The medical records management database system can not only record pre-operative and post-operative image data, but also provide doctors and patients to search at any time; It is the injury of deep tissue, which adopts two control methods. One is the active control method, and the other is the feedback control method. The former is based on the analysis of the characteristics of the tissue to be resected, and after a large number of repeated experiments, the optimal control parameters are summarized, and automatic control is realized through a preset program. The latter method uses a camera device to detect changes in the brightness and color of the cut hole in real time. Experiments have found that hole cutting is often accompanied by sudden changes in light intensity and color. Timely detection of this sudden change and feedback control of laser shutdown can effectively prevent laser damage; the red laser in the visible light band is used as a guide light, and the feedback control It is necessary to detect the change of the light intensity or color when the hole is cut through. In order to avoid the interference of the red guide light on the detection, two methods are adopted: one is to use a laser other than red as the guide light, and the other is to use the main controller to control the timely Automatically turns off the guide light.
附图说明 Description of drawings
以下结合附图和实施例对本发明详细说明。The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.
图1自控激光手术设备的示意图Figure 1 Schematic diagram of self-controlled laser surgery equipment
图2自控激光手术设备的局部剖视示意图Fig. 2 Schematic diagram of partial cutaway of self-controlled laser surgery equipment
图3自控激光手术设备的示意图Figure 3 Schematic diagram of self-controlled laser surgery equipment
图4自控激光手术设备的内窥镜(A)和观测治疗端部(B)的示意图Figure 4 Schematic diagram of the endoscope (A) and observation treatment end (B) of the self-controlled laser surgery equipment
图5自控激光手术设备的治疗方法的流程示意框图Fig. 5 Schematic block diagram of the treatment method of the self-controlled laser surgery equipment
1主支架,2悬臂,3悬挂手术治疗头,4显微观察系统,5显微观察镜,6显微手术适配器,7光源接口,8CCD摄像头,9激光器,10主控制器,11显示器,12脚踏开关,13摄像输出端口,14适配器输入端口,15光学镜片组,16内窥镜,17激光输出端口,18激光控制连接端口,19活检口,20气孔,21水口,22观测治疗端部,23内窥镜数据端口,24光源头,25图像采集头,26气孔端口,27水孔端口,28活检口端口,29光源设备,30光源输出端口,31控制激光器连接端口,32数据信息接口,33显示器连接端口1 main bracket, 2 cantilever, 3 suspended surgical treatment head, 4 microscopic observation system, 5 microscopic observation mirror, 6 microsurgical adapter, 7 light source interface, 8CCD camera, 9 laser, 10 main controller, 11 display, 12 Foot switch, 13 camera output port, 14 adapter input port, 15 optical lens group, 16 endoscope, 17 laser output port, 18 laser control connection port, 19 biopsy port, 20 air hole, 21 water port, 22 observation and treatment end , 23 endoscope data port, 24 light source head, 25 image acquisition head, 26 air hole port, 27 water hole port, 28 biopsy port, 29 light source device, 30 light source output port, 31 control laser connection port, 32 data information interface , 33 monitor connection ports
具体实施方式 Detailed ways
实施例1Example 1
由主控制器(10)、显示器(11)、CCD摄像头(8)、激光器(9)、光源设备(29)、主支架(1)、悬臂(2)、悬挂手术治疗头(3)、显微观察系统(4)和显微手术适配器(6)组成。It consists of a main controller (10), a display (11), a CCD camera (8), a laser (9), a light source device (29), a main support (1), a cantilever (2), a suspension surgical treatment head (3), a display It consists of a micro-observation system (4) and a micro-surgery adapter (6).
CCD摄像头(8)的摄像输出端(13)通过线路与主控制器(10)相连接,激光器(9)的激光控制连接端口(18)通过线路与主控制器(10)相连接,激光器(9)的激光输出端口(17)通过光导纤维导线与显微手术适配器(6)的适配器输入端口(14)相连接,CCD摄像头(8)采集病灶组织和正常组织的图像和光谱并通过摄像输出端(13)传输给主控制器(10)。The camera output terminal (13) of the CCD camera (8) is connected with the main controller (10) by the line, and the laser control connection port (18) of the laser device (9) is connected with the main controller (10) by the line, and the laser device ( 9) the laser output port (17) is connected with the adapter input port (14) of the microsurgical adapter (6) through the optical fiber wire, and the image and spectrum of the lesion tissue and normal tissue are collected by the CCD camera (8) and output through the camera. Terminal (13) is transmitted to main controller (10).
主控制器(10)识别和处理CCD摄像头(8)采集的病灶组织和正常组织的图像和光谱,并相应地发出指令控制激光器(9)的操作,避免激光手术的误操作损伤正常组织导致手术的失误。The main controller (10) recognizes and processes the images and spectra of the lesion tissue and normal tissue collected by the CCD camera (8), and sends instructions accordingly to control the operation of the laser (9), so as to avoid damage to normal tissue caused by misoperation of laser surgery and cause surgery mistakes.
显示器(11)与主控制器(10)的显示器连接端口(33)相连接,采用显示屏或触摸屏作为主控制器(10)的显示器(11),显示器(11)即时显示CCD摄像头(8)所采集的病灶组织和正常组织的图像和光谱,同时显示器(11)上显示手术参数。Display (11) is connected with the display connection port (33) of main controller (10), adopts display screen or touch screen as the display (11) of main controller (10), and display (11) shows CCD camera (8) immediately The images and spectra of the collected lesion tissue and normal tissue are displayed, and the operation parameters are displayed on the monitor (11).
激光器(9)的激光输出端口(17)通过光导纤维或导光臂与显微手术适配器(6)的适配器输入端口(14)相连接,传输治疗用激光,治疗用激光器(9)采用脉冲式工作方式的气体激光器或固体激光器或半导体激光器或光纤激光器,脉冲宽度:250μs~100ms,能量密度:5~20J/cm2,脉冲频率:<200Hz。The laser output port (17) of the laser (9) is connected to the adapter input port (14) of the microsurgical adapter (6) through an optical fiber or a light guide arm to transmit therapeutic laser light. The therapeutic laser (9) adopts pulsed Working mode of gas laser or solid laser or semiconductor laser or fiber laser, pulse width: 250μs ~ 100ms, energy density: 5 ~ 20J/cm 2 , pulse frequency: <200Hz.
激光器(9)的激光控制连接端口(18)通过线路与主控制器(10)的控制激光器连接端口(31)相连接,主控制器(10)发出指令控制激光器(9)的开机、关机以及修正激光输出量。The laser control connection port (18) of the laser device (9) is connected with the control laser connection port (31) of the main controller (10) by a line, and the main controller (10) sends instructions to control the start-up, shutdown and shutdown of the laser device (9). Correct the laser output.
主支架(1)的上部设置悬臂(2),悬臂(2)的一端部设置悬挂手术治疗头(3),主支架(1)和悬臂(2)支撑悬吊悬挂手术治疗头(3),悬挂手术治疗头(3)在悬臂(2)的端部保持治疗状态或自由移动。The upper part of the main support (1) is provided with a cantilever (2), and one end of the cantilever (2) is provided with a suspended surgical treatment head (3), and the main support (1) and the cantilever (2) support the suspended suspension surgical treatment head (3), The suspended surgical treatment head (3) maintains a treatment state or moves freely at the end of the cantilever (2).
悬挂手术治疗头(3)的上部设置显微观察系统(4)和显微观察镜(5),悬挂手术治疗头(3)的一侧设置CCD摄像头(8),CCD摄像头(8)的摄像输出端(13)通过线路与主控制器(10)的数据信息接口(32)相连接,即时把捕获到的图像和光谱传输给主控制器(10)。A microscopic observation system (4) and a microscopic observation mirror (5) are arranged on the top of the suspended surgical treatment head (3), and a CCD camera (8) is set on one side of the suspended surgical treatment head (3), and the camera of the CCD camera (8) The output terminal (13) is connected with the data information interface (32) of the main controller (10) through a line, and the captured images and spectra are transmitted to the main controller (10) in real time.
悬挂手术治疗头(3)的下部设置显微手术适配器(6),显微手术适配器(6)的适配器输入端口(14)与激光器(9)相连接,悬挂手术治疗头(3)的一侧设置光源接口(7),光源设备(29)的光源输出端(30)通过光源接口(7)接通光源照明手术部位。A microsurgical adapter (6) is arranged on the lower part of the suspending surgical treatment head (3), and the adapter input port (14) of the microsurgical adapter (6) is connected with the laser (9), and one side of the suspended surgical treatment head (3) A light source interface (7) is provided, and the light source output terminal (30) of the light source device (29) is connected to a light source to illuminate the surgical site through the light source interface (7).
在悬挂手术治疗头(3)内设置光学镜片组(15),光学镜片组(15)形成光路,通过光学镜片组(15)将显微观察系统(4)、显微观察镜(5)、CCD摄像头(8)和显微手术适配器(6)构成一整体。The optical lens group (15) is set in the suspension operation treatment head (3), and the optical lens group (15) forms an optical path, and the microscopic observation system (4), the microscopic observation mirror (5), The CCD camera (8) and the microsurgical adapter (6) form a whole.
脚踏开关(12)与主控制器(10)相连接,启闭脚踏开关(12)通过主控制器(10)手动控制激光器(9)的启动和关闭,当手术中出现突发变故关闭脚踏开关(12)即刻关闭激光器(9),突发变故结束开启脚踏开关(12),恢复工作状态,如图1、图2所示。The foot switch (12) is connected with the main controller (10), and the opening and closing foot switch (12) manually controls the start and stop of the laser (9) through the main controller (10). The foot switch (12) turns off the laser (9) at once, and the sudden change ends and the foot switch (12) is turned on to resume the working state, as shown in Fig. 1 and Fig. 2 .
实施例2Example 2
由主控制器(10)、显示器(11)、图像采集头(25)、激光器(9)、光源设备(29)和内窥镜(16)组成,显示器(11)与主控制器(10)的显示器连接端口(33)相连接,采用通用显示器或触摸屏显示器作为主控制器(10)的显示器(11),显示器(11)即时显示CCD摄像头(8)所采集的病灶组织和正常组织的图像和光谱,同时显示器(11)上显示手术参数。Composed of a main controller (10), a display (11), an image acquisition head (25), a laser (9), a light source device (29) and an endoscope (16), the display (11) and the main controller (10) The monitor connection port (33) is connected, and a general-purpose monitor or a touch screen monitor is used as the monitor (11) of the main controller (10), and the monitor (11) immediately displays the images of the lesion tissue and normal tissue collected by the CCD camera (8) And spectrum, display operation parameter on the monitor (11) simultaneously.
内窥镜(16)的上部设置活检口(19)、气孔(20)、水孔(21)、光源接口(7)和内窥镜数据端口(23),活检口(19)、气孔(20)、水孔(21)和光源接口(7)由内窥镜(16)的上部贯通至观测治疗端部(22),在观测治疗端部(22)构成活检口端口(28)、气孔端口(26)、水孔端口(27)和光源头(24),被手术病灶组织汽化后产生的废气通过气孔端口(26)由气孔(20)排出,手术过程中被手术部位产生的组织液体及水分通过水孔端口(27)由水孔(21)排出,光源设备(29)的光源输出端口(30)通过内窥镜(16)的光源接口(7)由光纤束传输到观测治疗端口(22)的光源头(24),观测治疗端口(22)上至少设置3个光源头(24),光源头(24)照明手术的部位。The top of endoscope (16) is provided with biopsy port (19), air hole (20), water hole (21), light source interface (7) and endoscope data port (23), biopsy port (19), air hole (20 ), the water hole (21) and the light source interface (7) are penetrated from the upper part of the endoscope (16) to the observation and treatment end (22), and the biopsy port (28) and stomata port are formed at the observation and treatment end (22) (26), the water hole port (27) and the light source head (24), the waste gas produced after being vaporized by the surgical lesion tissue is discharged from the stomata (20) through the stomata port (26), and the tissue liquid and moisture produced by the surgical site during the operation Discharged from the water hole (21) through the water hole port (27), the light source output port (30) of the light source device (29) is transmitted to the observation treatment port (22) by the optical fiber bundle through the light source interface (7) of the endoscope (16) ), at least three light source heads (24) are arranged on the observation treatment port (22), and the light source head (24) illuminates the surgical site.
在内窥镜(16)的观测治疗端部(22)设置CCD摄像头(8)的图形采集头(25),内窥镜(16)上部设置的内窥镜数据端口(23)通过线路与主控制器(10)的数据信息接口(32)相连接并与主控制器(1)的图像卡相连接,CCD摄像头(8)的图形采集头(25)采集病灶组织和正常组织的图像和光谱,主控制器(10)识别和处理CCD摄像头(8)采集的病灶组织和正常组织的图像和光谱,并相应地发出指令控制激光器(9)的操作,避免激光手术的误操作损伤正常组织导致手术的失误。The observation and treatment end portion (22) of the endoscope (16) is provided with the image acquisition head (25) of the CCD camera (8), and the endoscope data port (23) provided on the top of the endoscope (16) is connected with the host through the line. The data information interface (32) of the controller (10) is connected and connected with the image card of the main controller (1), and the image and spectrum of the image acquisition head (25) of the CCD camera (8) collects lesion tissue and normal tissue , the main controller (10) recognizes and processes the images and spectra of the lesion tissue and normal tissue collected by the CCD camera (8), and correspondingly issues instructions to control the operation of the laser (9), so as to avoid damage to normal tissue caused by misoperation of laser surgery. Surgical error.
激光器(9)的激光输出端口(17)连接光导纤维,把光导纤维从内窥镜(16)的活检口(19)插入,光导纤维的端部直至观测治疗端口(22)处的活检口端口(28),传输治疗用激光,治疗用激光器采用脉冲式工作方式的气体激光器或固体激光器或半导体激光器或光纤激光器,脉冲宽度:250μs~100ms,能量密度:5~20J/cm2,脉冲频率:<200Hz。The laser output port (17) of the laser (9) is connected to the optical fiber, the optical fiber is inserted from the biopsy port (19) of the endoscope (16), and the end of the optical fiber reaches the biopsy port at the observation treatment port (22) (28) Transmission of therapeutic lasers. The therapeutic lasers are gas lasers or solid-state lasers or semiconductor lasers or fiber lasers in a pulsed working mode. Pulse width: 250μs-100ms, energy density: 5-20J/cm 2 , pulse frequency: <200Hz.
激光器(9)的激光控制连接端口(18)通过线路与主控制器(10)的控制激光器连接端口(31)相连接,主控制器(10)发出指令控制激光器(9)的开机、关机以及修正激光输出量。The laser control connection port (18) of the laser device (9) is connected with the control laser connection port (31) of the main controller (10) by a line, and the main controller (10) sends instructions to control the start-up, shutdown and shutdown of the laser device (9). Correct the laser output.
脚踏开关(12)与主控制器(10)相连接,启闭脚踏开关(12)通过主控制器(10)手动控制激光器(9)的启动和关闭,当手术中出现突发变故关闭脚踏开关(12)即刻关闭激光器(9),突发变故结束开启脚踏开关(12),恢复工作状态,如图3、图4所示。The foot switch (12) is connected with the main controller (10), and the opening and closing foot switch (12) manually controls the start and stop of the laser (9) through the main controller (10). The foot switch (12) turns off the laser (9) at once, and the sudden change ends and the foot switch (12) is turned on to resume the working state, as shown in Fig. 3 and Fig. 4 .
实施例3Example 3
术前准备后,开启主控制器(10)、显示器(11)、CCD摄像头(8)和光源设备(29),调整主支架(1)上的悬臂(2)和悬挂手术治疗头(3),治疗端进入手术区域,把悬挂手术治疗头(3)上的显微手术适配器(6)对准手术部位。After the preoperative preparation, turn on the main controller (10), monitor (11), CCD camera (8) and light source equipment (29), adjust the cantilever (2) on the main bracket (1) and suspend the surgical treatment head (3) , the treatment end enters the operation area, and the microsurgical adapter (6) on the suspended operation treatment head (3) is aligned with the operation site.
通过悬挂手术治疗头(3)上的显微观察系统(4)和显示器(11)显示的图像和光谱,观察手术部位的病灶组织和正常组织,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,将显微手术适配器(6)锁定病灶组织部位。By suspending the images and spectra displayed by the microscopic observation system (4) and the monitor (11) on the surgical treatment head (3), observe the lesion tissue and normal tissue at the surgical site, and the main controller (10) identifies and confirms the lesion tissue and the normal tissue. For images and spectra of normal tissues, lock the microsurgical adapter (6) on the lesion tissue site.
开启激光器(9),主控制器(10)修正激光器(9)的手术参数,调整激光器(9)的输出功率,激光器(9)准备开机出光。Turn on the laser (9), the main controller (10) corrects the surgical parameters of the laser (9), adjusts the output power of the laser (9), and the laser (9) is ready to start up and emit light.
锁定病灶组织,主控制器发“开机”出操作指令,激光器(9)开机出光,激光器(9)输出治疗激光,激光器(9)的治疗激光切割或汽化手术部位的病灶组织,治疗激光采用脉冲式工作方式的气体激光器或固体激光器或半导体激光器或光纤激光器,脉冲宽度:250μs~100ms,能量密度:5~20J/cm2,脉冲频率:<200Hz。Lock the lesion tissue, the main controller sends out the operation command of "starting up", the laser (9) starts to emit light, the laser (9) outputs the treatment laser, the treatment laser (9) cuts or vaporizes the lesion tissue of the surgical site, and the treatment laser adopts pulse Gas laser or solid-state laser or semiconductor laser or fiber laser with working mode, pulse width: 250μs-100ms, energy density: 5-20J/cm 2 , pulse frequency: <200Hz.
CCD摄像头(8)始终把捕获到的图像和光谱反馈给主控制器(10),显示器(11)始终显示CCD摄像头(8)捕获到的图像和光谱,主控制器(10)随时监控捕获到的图像和光谱的变化,并及时对激光器(9)发出操作指令,停机或开机或修正激光的输出量。CCD camera (8) feeds back the captured image and spectrum to main controller (10) all the time, and display (11) shows the image and spectrum captured by CCD camera (8) all the time, and main controller (10) monitors and captures at any time changes in the image and spectrum of the laser, and issue an operation command to the laser (9) in time, stop or start up or correct the output of the laser.
脚踏开关(12)与主控制器(10)相连接,启闭脚踏开关(12)通过主控制器(10)控制激光器(9)的开机和关机。The foot switch (12) is connected with the master controller (10), and the on-off foot switch (12) controls the start-up and shutdown of the laser (9) by the master controller (10).
当病灶组织的图像和光谱一消失,CCD摄像头(8)将捕获到正常组织的图像和光谱反馈给主控制器(10),主控制器(10)监控到正常组织的图像和光谱出现,即时对激光器(9)发出“停机”操作的指令,激光器(9)接到“停机”操作指令,在发出下一个脉冲激光前停止输出激光,不损伤正常组织。When the image and spectrum of the lesion tissue disappear, the CCD camera (8) will capture the image and spectrum of the normal tissue and feed it back to the main controller (10), and the main controller (10) will monitor the appearance of the image and spectrum of the normal tissue. The laser (9) is instructed to "shut down" operation, and the laser (9) receives the "shutdown" operation instruction, and stops outputting laser light before sending out the next pulse laser, without damaging normal tissues.
调整主支架(1)上的悬臂(2)和悬挂手术治疗头(3),寻找手术部位的病灶组织,把悬挂手术治疗头(3)上的显微手术适配器(6)对准手术部位的病灶组织,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,锁定病灶组织,主控制器发出操作指令,激光器(9)开机出光,激光器(9)输出治疗激光,激光器(9)的治疗激光切割或汽化手术部位的病灶组织,往复循环,直至完全消除手术部位的病灶组织。Adjust the cantilever (2) and the suspended surgical treatment head (3) on the main support (1), find the lesion tissue of the surgical site, and align the microsurgical adapter (6) on the suspended surgical treatment head (3) with the surface of the surgical site. For the lesion tissue, the main controller (10) identifies and confirms the image and spectrum of the lesion tissue and normal tissue, locks the lesion tissue, the main controller issues an operation command, the laser (9) turns on and emits light, and the laser (9) outputs a therapeutic laser, and the laser ( 9) The treatment of laser cutting or vaporizing the lesion tissue at the operation site, reciprocating cycle until the lesion tissue at the operation site is completely eliminated.
当完全消除手术部位的病灶组织,关闭激光器(9)停止输出治疗激光;通过悬挂手术治疗头(3)上的显微观察系统(4)和显示器(11)显示的图像观察手术部位的正常组织和病灶组织,主控制器(10)确认手术部位完全消除病灶组织后,移动主支架(1)上的悬臂(2)和悬挂手术治疗头(3),把悬挂手术治疗头(3)上的显微手术适配器(6)从手术部位移开。When the lesion tissue at the surgical site is completely eliminated, turn off the laser (9) to stop outputting the therapeutic laser; observe the normal tissue at the surgical site through the images displayed by the microscopic observation system (4) and the monitor (11) suspended on the surgical treatment head (3) and focus tissue, after the main controller (10) confirms that the operation site completely eliminates the focus tissue, it moves the cantilever (2) on the main support (1) and the suspending surgical treatment head (3), and puts the suspension arm (2) on the surgical treatment head (3) The microsurgical adapter (6) moves away from the surgical site.
关闭主控制器(10)、显示器(11)、CCD摄像头(8)和光源,手术结束,如图1、图2、图5所示。Turn off the main controller (10), display (11), CCD camera (8) and light source, and the operation ends, as shown in Figure 1, Figure 2, and Figure 5.
实施例4Example 4
脚踏开关(12)与主控制器(10)相连接,当手术中出现突发变故,关闭脚踏开关(12),脚踏开关(12)通过主控制器(10)关闭激光器(9),激光器(9)即刻停机,停止输出治疗激光;The foot switch (12) is connected with the main controller (10). When a sudden change occurs during the operation, the foot switch (12) is turned off, and the foot switch (12) turns off the laser (9) through the main controller (10). , the laser (9) shuts down immediately, and stops outputting the therapeutic laser;
当突发变故结束,开启脚踏开关(12),激光器(9)恢复工作状态,如图1、图5所示。When the sudden change ends, the foot switch (12) is turned on, and the laser (9) returns to the working state, as shown in Fig. 1 and Fig. 5 .
实施例5Example 5
术前准备后,开启主控制器(10)、显示器(11)、光源设备(29)和CCD摄像头(8),开启光源设备(29)观测治疗端口(22)的3个光源头(24)照明手术的部位,内窥镜(16)的观测治疗端部(22)进入手术区域,对准手术部位。After the preoperative preparation, turn on the main controller (10), display (11), light source device (29) and CCD camera (8), and turn on the light source device (29) to observe the three light source heads (24) of the treatment port (22) The site of the illumination operation is illuminated, and the observation and treatment end (22) of the endoscope (16) enters the operation area and is aimed at the operation site.
激光器(9)的激光输出端口(17)连接光导纤维,把光导纤维从内窥镜(16)的活检口(19)插入,光导纤维的端部直至观测治疗端口(22)处的活检口端口(28),在观测治疗端口(22)处出光治疗病灶。The laser output port (17) of the laser (9) is connected to the optical fiber, the optical fiber is inserted from the biopsy port (19) of the endoscope (16), and the end of the optical fiber reaches the biopsy port at the observation treatment port (22) (28), emit light at the observation treatment port (22) to treat the lesion.
将内窥镜(16)的观测治疗端口(22)对准手术部位,通过显示器(11)显示手术部位的图像和光谱,观察手术部位的病灶组织和正常组织,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱。Align the observation and treatment port (22) of the endoscope (16) at the surgical site, display images and spectra of the surgical site through the monitor (11), observe the lesion tissue and normal tissue at the surgical site, and the main controller (10) recognizes, Confirm images and spectra of lesion and normal tissue.
通过主控制器(10)修正手术参数,调整激光器(9)的输出功率,激光器(9)准备开机出光。The operation parameters are corrected by the main controller (10), the output power of the laser (9) is adjusted, and the laser (9) is ready to be turned on to emit light.
锁定病灶组织,主控制器发出操作指令,激光器(9)开机出光,激光器(9)输出治疗激光,激光器(9)的治疗激光切割或汽化手术部位的病灶组织,治疗用激光采用脉冲式工作方式的气体激光器或固体激光器或半导体激光器或光纤激光器,脉冲宽度:250μs~100ms,能量密度:5~20J/cm2,脉冲频率:<200Hz。The lesion tissue is locked, the main controller issues an operation command, the laser (9) is turned on and emits light, and the laser (9) outputs a therapeutic laser. The therapeutic laser (9) cuts or vaporizes the lesion tissue at the surgical site, and the therapeutic laser adopts a pulsed working mode Gas laser or solid laser or semiconductor laser or fiber laser, pulse width: 250μs-100ms, energy density: 5-20J/cm 2 , pulse frequency: <200Hz.
CCD摄像头(8)始终把捕获到的图像和光谱反馈给主控制器(10),显示器(11)始终显示CCD摄像头(8)捕获到的图像和光谱,主控制器(10)随时监控捕获到的图像和光谱的变化,并及时对激光器(9)发出操作指令,停机或开机或修正激光的输出量。CCD camera (8) feeds back the captured image and spectrum to main controller (10) all the time, and display (11) shows the image and spectrum captured by CCD camera (8) all the time, and main controller (10) monitors and captures at any time changes in the image and spectrum of the laser, and issue an operation command to the laser (9) in time, stop or start up or correct the output of the laser.
在手术过程中被手术的病灶组织汽化后产生的废气通过气孔端口(26)由气孔(20)排出,手术过程中被手术的部位产生的组织液体及水分通过水孔端口(27)由水孔(21)排出。During the operation, the waste gas produced by the vaporization of the operated lesion tissue passes through the stomata port (26) and is discharged from the stomata (20), and the tissue liquid and moisture generated at the operated site pass through the water hole port (27) through the water hole. (21) DISCHARGE.
当病灶组织的图像和光谱一消失,CCD摄像头(8)将捕获到正常组织的图像和光谱反馈给主控制器(10),主控制器(10)监控到正常组织的图像和光谱出现,即时对激光器(9)发出“停机”操作的指令,激光器(9)接到“停机”操作指令,在发出下一个脉冲激光前停止输出激光,不损伤正常组织。When the image and spectrum of the lesion tissue disappear, the CCD camera (8) will capture the image and spectrum of the normal tissue and feed it back to the main controller (10), and the main controller (10) will monitor the appearance of the image and spectrum of the normal tissue. The laser (9) is instructed to "shut down" operation, and the laser (9) receives the "shutdown" operation instruction, and stops outputting laser light before sending out the next pulse laser, without damaging normal tissues.
调整内窥镜(16)的观测治疗端口(22),寻找手术部位的病灶组织,将内窥镜(16)的观测治疗端口(22)对准手术部位的病灶组织,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,锁定病灶组织,主控制器发出操作指令,激光器(9)开机出光,激光器(9)输出治疗激光,激光器(9)的治疗激光切割或汽化手术部位的病灶组织,往复循环,直至完全消除手术部位的病灶组织。Adjust the observation and treatment port (22) of the endoscope (16), find the lesion tissue of the surgical site, align the observation and treatment port (22) of the endoscope (16) with the focus tissue of the surgical site, and the main controller (10) Identify and confirm the image and spectrum of the lesion tissue and normal tissue, lock the lesion tissue, the main controller issues an operation instruction, the laser (9) turns on and emits light, the laser (9) outputs therapeutic laser, and the therapeutic laser cutting or vaporization surgery of the laser (9) The lesion tissue at the surgical site is reciprocated until the focal tissue at the surgical site is completely eliminated.
当完全消除手术部位的病灶组织,关闭激光器(9)停止输出治疗激光。When the lesion tissue at the operation site is completely eliminated, the laser (9) is turned off to stop outputting the therapeutic laser.
通过显示器(11)显示的图像观察手术部位的正常组织和病灶组织,主控制器(10)确认手术部位完全消除病灶组织后,内窥镜(16)的观测治疗端口(22)退出手术部位,关闭主控制器(10)、显示器(11)、CCD摄像头(8)和光源设备(29),手术结束,如图3、图4、图5所示。Observe the normal tissue and the lesion tissue of the operation site through the image displayed on the monitor (11), after the master controller (10) confirms that the operation site has completely eliminated the focus tissue, the observation and treatment port (22) of the endoscope (16) withdraws from the operation site, Close main controller (10), display (11), CCD camera (8) and light source equipment (29), operation finishes, as shown in Fig. 3, Fig. 4, Fig. 5.
实施例6Example 6
脚踏开关(12)与主控制器(10)相连接,当手术中出现突发变故,关闭脚踏开关(12),脚踏开关(12)通过主控制器(10)关闭激光器(9),激光器(9)即刻停机,停止输出治疗激光。The foot switch (12) is connected with the main controller (10). When a sudden change occurs during the operation, the foot switch (12) is turned off, and the foot switch (12) turns off the laser (9) through the main controller (10). , the laser (9) shuts down immediately, and stops outputting the therapeutic laser.
当突发变故结束,开启脚踏开关(12),激光器(9)恢复工作状态,如图3、图5所示。When the sudden change ends, the foot switch (12) is turned on, and the laser (9) returns to the working state, as shown in Fig. 3 and Fig. 5 .
实施例7Example 7
术前准备后,开机,内窥镜(16)的观测治疗端口(22)进入鼻腔,对准手术部位--鼻息肉,CCD摄像头(8)即时捕获手术部位的病灶组织和正常组织的图像和光谱,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,主控制器(10)修正激光器(9)的手术参数,激光器(9)准备出光;锁定鼻息肉的病灶组织,主控制器(10)发出操作指令,激光器(9)出光,主控制器(10)随时监控CCD摄像头(13)捕获手术部位的病灶组织和正常组织的图像和光谱,病灶组织的图像和光谱一消失,主控制器(10)即刻指令激光器(9)停机;在鼻腔内的手术部位寻找鼻息肉的病灶组织,在鼻腔内手术部位发现鼻息肉的病灶组织,将内窥镜(16)的观测治疗端口(22)对准手术部位的病灶组织,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,锁定病灶组织,主控制器发出操作指令,激光器(9)开机出光,激光器(9)输出治疗激光,激光器(9)的治疗激光切割或汽化手术部位的病灶组织,往复循环,直至完全消除手术部位的病灶组织。After the preoperative preparation, start the machine, the observation treatment port (22) of the endoscope (16) enters the nasal cavity, aligns with the surgical site—nasal polyps, and the CCD camera (8) captures images and images of the lesion tissue and normal tissue at the surgical site in real time. Spectrum, the main controller (10) identifies and confirms the image and spectrum of the lesion tissue and normal tissue, the main controller (10) corrects the surgical parameters of the laser (9), and the laser (9) is ready to emit light; lock the lesion tissue of the nasal polyp, The main controller (10) sends out operation instructions, the laser (9) emits light, and the main controller (10) monitors the CCD camera (13) at any time to capture the image and spectrum of the lesion tissue and normal tissue at the surgical site. disappear, the main controller (10) immediately instructs the laser (9) to shut down; look for the focal tissue of nasal polyps at the surgical site in the nasal cavity, find the focal tissue of nasal polyps at the surgical site in the nasal cavity, and use the observation of the endoscope (16) The treatment port (22) is aligned with the lesion tissue at the surgical site, the main controller (10) identifies and confirms the images and spectra of the lesion tissue and normal tissue, locks the lesion tissue, the main controller issues an operation command, and the laser (9) starts to emit light. The laser (9) outputs therapeutic laser, and the therapeutic laser of the laser (9) cuts or vaporizes the lesion tissue at the operation site, and reciprocates until the lesion tissue at the operation site is completely eliminated.
当完全消除手术部位的病灶组织,关闭激光器(9)停止输出治疗激光。通过显示器(11)显示的图像观察手术部位的正常组织和病灶组织,主控制器(10)确认手术部位完全消除鼻息肉的病灶组织后,内窥镜(16)的观测治疗端口(22)退出鼻腔,关闭主控制器(10)、显示器(11)、CCD摄像头(8)和光源设备(29),手术结束,如图3、图4、图5所示。When the lesion tissue at the operation site is completely eliminated, the laser (9) is turned off to stop outputting the therapeutic laser. Observe the normal tissue and lesion tissue of the surgical site through the image displayed on the monitor (11), and after the main controller (10) confirms that the surgical site has completely eliminated the focal tissue of the nasal polyps, the observation treatment port (22) of the endoscope (16) exits Nasal cavity, close master controller (10), display (11), CCD camera (8) and light source equipment (29), operation finishes, as shown in Fig. 3, Fig. 4, Fig. 5.
实施例8Example 8
术前准备后,开机,内窥镜(16)的观测治疗端口(22)进入口腔,对准手术部位-喉癌,CCD摄像头(8)即时捕获手术部位的病灶组织和正常组织的图像和光谱,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,主控制器(10)修正激光器(9)的手术参数,激光器(9)准备出光;锁定喉癌的病灶组织,主控制器(10)发出操作指令,激光器(9)出光,主控制器(10)随时监控CCD摄像头(13)捕获手术部位的病灶组织和正常组织的图像和光谱,病灶组织的图像和光谱一消失,主控制器(10)即刻指令激光器(9)停机;在口腔内的手术部位寻找喉癌的病灶组织,在口腔内手术部位发现喉癌的病灶组织,将内窥镜(16)的观测治疗端口(22)对准手术部位的病灶组织,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,锁定喉癌的病灶组织,主控制器发出操作指令,激光器(9)开机出光,激光器(9)输出治疗激光,激光器(9)的治疗激光切割或汽化手术部位的病灶组织,往复循环,直至完全消除手术部位的喉癌病灶组织。After the preoperative preparation, turn on the machine, the observation and treatment port (22) of the endoscope (16) enters the oral cavity, and aligns with the surgical site - laryngeal cancer, and the CCD camera (8) captures the images and spectra of the lesion tissue and normal tissue at the surgical site in real time , the main controller (10) identifies and confirms the images and spectra of the lesion tissue and normal tissue, the main controller (10) corrects the surgical parameters of the laser (9), and the laser (9) is ready to emit light; the lesion tissue of laryngeal cancer is locked, and the main The controller (10) sends out operation instructions, the laser (9) emits light, and the main controller (10) monitors the CCD camera (13) at any time to capture images and spectra of the lesion tissue and normal tissue at the surgical site, and the image and spectrum of the lesion tissue disappear , the main controller (10) immediately instructs the laser (9) to shut down; look for the lesion tissue of laryngeal cancer at the surgical site in the oral cavity, find the lesion tissue of laryngeal cancer at the surgical site in the oral cavity, and use the observation and treatment of the endoscope (16) The port (22) is aligned with the lesion tissue at the surgical site, the main controller (10) identifies and confirms the image and spectrum of the lesion tissue and normal tissue, locks the lesion tissue of laryngeal cancer, the main controller issues an operation command, and the laser (9) is turned on Light is emitted, and the laser (9) outputs a therapeutic laser. The therapeutic laser of the laser (9) cuts or vaporizes the lesion tissue at the operation site, and reciprocates until the laryngeal cancer focus tissue at the operation site is completely eliminated.
当完全消除手术部位的病灶组织,关闭激光器(9)停止输出治疗激光。通过显示器(11)显示的图像观察手术部位的正常组织和病灶组织,主控制器(10)确认手术部位完全消除喉癌的病灶组织后,内窥镜(16)的观测治疗端口(22)退出口腔,关闭主控制器(10)、显示器(11)、CCD摄像头(8)和光源设备(29),手术结束,如图3、图4、图5所示。When the lesion tissue at the operation site is completely eliminated, the laser (9) is turned off to stop outputting the therapeutic laser. Observe the normal tissue and lesion tissue of the operation site through the image displayed on the monitor (11), and after the main controller (10) confirms that the lesion tissue of the laryngeal cancer is completely eliminated in the operation site, the observation treatment port (22) of the endoscope (16) exits Oral cavity, close master controller (10), display (11), CCD camera (8) and light source equipment (29), operation finishes, as shown in Figure 3, Figure 4, Figure 5.
实施例9Example 9
术前准备后,开机,内窥镜(16)的观测治疗端口(22)从口腔进入食道,对准手术部位-食道癌,CCD摄像头(8)即时捕获手术部位的病灶组织和正常组织的图像和光谱,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,主控制器(10)修正激光器(9)的手术参数,激光器(9)准备出光;锁定食道癌的病灶组织,主控制器(10)发出操作指令,激光器(9)出光,主控制器(10)随时监控CCD摄像头(13)捕获手术部位的病灶组织和正常组织的图像和光谱,病灶组织的图像和光谱一消失,主控制器(10)即刻指令激光器(9)停机;在食道内的手术部位寻找食道癌的病灶组织,在食道内手术部位发现食道癌的病灶组织,将内窥镜(16)的观测治疗端口(22)对准手术部位的病灶组织,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,锁定食道癌的病灶组织,主控制器发出操作指令,激光器(9)开机出光,激光器(9)输出治疗激光,激光器(9)的治疗激光切割或汽化手术部位的病灶组织,往复循环,直至完全消除手术部位的食道癌病灶组织。After the preoperative preparation, start the machine, the observation and treatment port (22) of the endoscope (16) enters the esophagus from the oral cavity, and aligns with the surgical site-esophageal cancer, and the CCD camera (8) captures images of the lesion tissue and normal tissue at the surgical site in real time and spectrum, the main controller (10) identifies and confirms the image and spectrum of the lesion tissue and normal tissue, the main controller (10) revises the surgical parameters of the laser (9), and the laser (9) is ready to emit light; lock the lesion tissue of esophageal cancer , the main controller (10) sends an operation command, the laser (9) emits light, and the main controller (10) monitors the CCD camera (13) at any time to capture the images and spectra of the lesion tissue and normal tissue at the surgical site, and the image and spectrum of the lesion tissue As soon as it disappears, the main controller (10) immediately instructs the laser (9) to shut down; look for the lesion tissue of esophageal cancer at the surgical site in the esophagus, find the lesion tissue of the esophageal cancer at the surgical site in the esophagus, and place the endoscope (16) The observation treatment port (22) is aimed at the lesion tissue of the operation site, the main controller (10) identifies and confirms the images and spectra of the lesion tissue and normal tissue, locks the lesion tissue of esophageal cancer, the main controller issues an operation instruction, and the laser (9 ) is turned on to emit light, the laser (9) outputs a therapeutic laser, and the therapeutic laser of the laser (9) cuts or vaporizes the lesion tissue at the operation site, and reciprocates until the esophageal cancer focus tissue at the operation site is completely eliminated.
当完全消除手术部位的病灶组织,关闭激光器(9)停止输出治疗激光。通过显示器(11)显示的图像观察手术部位的正常组织和病灶组织,主控制器(10)确认手术部位完全消除食道癌的病灶组织后,内窥镜(16)的观测治疗端口(22)退出口腔,关闭主控制器(10)、显示器(11)、CCD摄像头(8)和光源设备(29),手术结束,如图3、图4、图5所示。When the lesion tissue at the operation site is completely eliminated, the laser (9) is turned off to stop outputting the therapeutic laser. Observe the normal tissue and focus tissue of the operation site through the image displayed on the monitor (11), and after the main controller (10) confirms that the focus tissue of esophageal cancer is completely eliminated in the operation site, the observation treatment port (22) of the endoscope (16) exits Oral cavity, close master controller (10), display (11), CCD camera (8) and light source equipment (29), operation finishes, as shown in Figure 3, Figure 4, Figure 5.
实施例10Example 10
术前准备后,开机,内窥镜(16)的观测治疗端口(22)从口腔通过食道进入胃部,对准手术部位-胃癌,CCD摄像头(8)即时捕获手术部位的病灶组织和正常组织的图像和光谱,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,主控制器(10)修正激光器(9)的手术参数,激光器(9)准备出光;锁定胃癌的病灶组织,主控制器(10)发出操作指令,激光器(9)出光,主控制器(10)随时监控CCD摄像头(13)捕获手术部位的病灶组织和正常组织的图像和光谱,病灶组织的图像和光谱一消失,主控制器(10)即刻指令激光器(9)停机;在胃内的手术部位寻找胃癌的病灶组织,在胃内手术部位发现胃癌的病灶组织,将内窥镜(16)的观测治疗端口(22)对准手术部位的病灶组织,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,锁定胃癌的病灶组织,主控制器发出操作指令,激光器(9)开机出光,激光器(9)输出治疗激光,激光器(9)的治疗激光切割或汽化手术部位的病灶组织,往复循环,直至完全消除手术部位的胃癌病灶组织。After the preoperative preparation, turn on the machine, the observation and treatment port (22) of the endoscope (16) enters the stomach from the oral cavity through the esophagus, and is aimed at the surgical site - gastric cancer, and the CCD camera (8) captures the lesion tissue and normal tissue of the surgical site in real time images and spectra, the main controller (10) identifies and confirms the images and spectra of the lesion tissue and normal tissue, the main controller (10) corrects the surgical parameters of the laser (9), and the laser (9) is ready to emit light; the focus of gastric cancer is locked tissue, the main controller (10) sends out operation instructions, the laser (9) emits light, and the main controller (10) monitors the CCD camera (13) at any time to capture the image and spectrum of the lesion tissue and normal tissue at the surgical site, the image of the lesion tissue and As soon as the spectrum disappears, the main controller (10) immediately instructs the laser (9) to shut down; search for the lesion tissue of gastric cancer at the surgical site in the stomach, find the lesion tissue of gastric cancer at the surgical site in the stomach, and use the observation of the endoscope (16) The treatment port (22) is aimed at the lesion tissue of the surgical site, the main controller (10) identifies and confirms the images and spectra of the lesion tissue and normal tissue, locks the lesion tissue of gastric cancer, the main controller issues an operation command, and the laser (9) is turned on Light is emitted, and the laser (9) outputs therapeutic laser. The therapeutic laser of the laser (9) cuts or vaporizes the lesion tissue at the operation site, and reciprocates until the gastric cancer lesion tissue at the operation site is completely eliminated.
当完全消除手术部位的病灶组织,关闭激光器(9)停止输出治疗激光。通过显示器(11)显示的图像观察手术部位的正常组织和病灶组织,主控制器(10)确认手术部位完全消除胃癌的病灶组织后,内窥镜(16)的观测治疗端口(22)退出口腔,关闭主控制器(10)、显示器(11)、CCD摄像头(8)和光源设备(29),手术结束,如图3、图4、图5所示。When the lesion tissue at the operation site is completely eliminated, the laser (9) is turned off to stop outputting the therapeutic laser. The normal tissue and lesion tissue of the operation site are observed through the image displayed on the monitor (11), and after the main controller (10) confirms that the lesion tissue of gastric cancer is completely eliminated in the operation site, the observation and treatment port (22) of the endoscope (16) withdraws from the oral cavity , close main controller (10), display (11), CCD camera (8) and light source equipment (29), and operation finishes, as shown in Fig. 3, Fig. 4, Fig. 5.
实施例11Example 11
术前准备后,开机,内窥镜(16)的观测治疗端口(22)从肛门进入直肠,对准手术部位-直肠息肉,CCD摄像头(8)即时捕获手术部位的病灶组织和正常组织的图像和光谱,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,主控制器(10)修正激光器(9)的手术参数,激光器(9)准备出光;锁定直肠息肉的病灶组织,主控制器(10)发出操作指令,激光器(9)出光,主控制器(10)随时监控CCD摄像头(13)捕获手术部位的病灶组织和正常组织的图像和光谱,病灶组织的图像和光谱一消失,主控制器(10)即刻指令激光器(9)停机;在直肠内的手术部位寻找直肠息肉的病灶组织,在直肠内手术部位发现直肠息肉癌的病灶组织,将内窥镜(16)的观测治疗端口(22)对准手术部位的病灶组织,主控制器(10)识别、确认病灶组织和正常组织的图像和光谱,锁定直肠息肉的病灶组织,主控制器发出操作指令,激光器(9)开机出光,激光器(9)输出治疗激光,激光器(9)的治疗激光切割或汽化手术部位的病灶组织,往复循环,直至完全消除手术部位的直肠息肉病灶组织。After the preoperative preparation, turn on the machine, the observation and treatment port (22) of the endoscope (16) enters the rectum from the anus, and aligns with the surgical site-rectal polyp, and the CCD camera (8) captures the images of the lesion tissue and normal tissue at the surgical site in real time and spectrum, the main controller (10) identifies and confirms the image and spectrum of the lesion tissue and normal tissue, the main controller (10) revises the surgical parameters of the laser (9), and the laser (9) is ready to emit light; lock the lesion tissue of the rectal polyp , the main controller (10) sends an operation command, the laser (9) emits light, and the main controller (10) monitors the CCD camera (13) at any time to capture the images and spectra of the lesion tissue and normal tissue at the surgical site, and the image and spectrum of the lesion tissue As soon as it disappears, the main controller (10) immediately instructs the laser (9) to shut down; look for the lesion tissue of rectal polyp at the surgical site in the rectum, find the lesion tissue of rectal polyp cancer at the surgical site in the rectum, and place the endoscope (16) The observation treatment port (22) is aimed at the lesion tissue of the operation site, the main controller (10) identifies and confirms the images and spectra of the lesion tissue and normal tissue, locks the lesion tissue of the rectal polyp, the main controller issues an operation instruction, and the laser ( 9) Turn on the light, the laser (9) outputs therapeutic laser, the therapeutic laser of the laser (9) cuts or vaporizes the lesion tissue at the operation site, and reciprocates until the rectal polyp lesion tissue at the operation site is completely eliminated.
当完全消除手术部位的病灶组织,关闭激光器(9)停止输出治疗激光。通过显示器(11)显示的图像观察手术部位的正常组织和病灶组织,主控制器(10)确认手术部位完全消除直肠息肉的病灶组织后,内窥镜(16)的观测治疗端口(22)退出肛门,关闭主控制器(10)、显示器(11)、CCD摄像头(8)和光源设备(29),手术结束,如图3、图4、图5所示。When the lesion tissue at the operation site is completely eliminated, the laser (9) is turned off to stop outputting the therapeutic laser. Observe the normal tissue and lesion tissue of the operation site through the image displayed on the monitor (11), after the main controller (10) confirms that the lesion tissue of the rectal polyp is completely eliminated at the operation site, the observation treatment port (22) of the endoscope (16) exits Anus, close master controller (10), display (11), CCD camera (8) and light source equipment (29), operation finishes, as shown in Figure 3, Figure 4, Figure 5.
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