CN101658579A - Chinese medicinal composition for treating pig colibacillosis and preparation method thereof - Google Patents

Abstract

The invention relates to a Chinese medicinal composition for treating pig colibacillosis, which is characterized by comprising the following medicaments in parts by weight: 13 to 17 parts of Chinese pulsatilla root, 8 to 12 parts of argy wormwood leaves, 8 to 12 parts of coked hawthorn, 13 to 17 parts of pomegranate bark, 3 to 7 parts of liquorice, 8 to 12 parts of honeysuckle, 8 to 12 parts of fructus forsythiae, 13 to 17 parts of mung beans, and 8 to 12 parts of dried orange peel. The preparation method comprises the following steps: (1) weighing the Chinese pulsatilla root, the argy wormwood leaves, the coked hawthorn, the pomegranate bark, the liquorice, the honeysuckle, the fructus forsythiae, the mung beans and the dried orange peel as raw materials in parts by weight; and (2) crushing and screening the medicaments to enable the granularity to reach 60 to 200 meshes, evenly mixing the medicaments to obtain a finished product. The Chinese medicinal composition has the effect thatthe formula has the functions of clearing away heat and toxic materials, removing heat from the blood and relieving diarrhea, astringing intestine and arresting bleeding, regulating the flow of vitalenergy, strengthening the spleen, and alleviating water retention; and the liquorice with other compositions together play roles of clearing away heat and toxic materials, eliminating dampness, and inducing diuresis to alleviate edema based on the knowledge and treatment principle of Chinese veterinary science on pathogeny of the pig colibacillosis. The Chinese medicinal composition cannot generate drug resistance; no residue in a pig body when the pig eats the composition so as to guarantee edible safety of meat products.

Description

Chinese medicine composition of treatment colibacillosis of pigs and preparation method thereof

Technical field

The invention belongs to pig and use Chinese medicine, relate in particular to a kind of Chinese medicine composition for the treatment of colibacillosis of pigs and preparation method thereof.

Background technology

Colibacillosis of pigs is the one group of infectious disease based on piglet that is caused by colon bacillus.Clinical serves as typical case's representative with yellow scour of piglet, piglet pujos blancos and baby pig edema usually, is the important diseases of one group of harm piglet growth, each hog area all over the world.Mainly be to carry disease germs sow, intersperse among the external world, pollute nipple and the skin of sow by feces discharge pathogen bacterium.Piglet is sucked the breast or infects when licking sow.The pathogenic bacteria that the piglet of dysentery is discharged with feces pollutes other sow with water, feedstuff and apparatus, forms the new source of infection.Along with the continuous development, particularly intensive farm of pig industry, this disease takes place in some pig farms in various degree, has brought serious harm to pig industry, and has caused bigger economic loss.Treatment according to different disease routines: adopt chemotherapy or regularly thorough disinfection, reinforcement feeding and management are carried out in place, utensil etc.But above several method can make the pig body that drug residue or cure diseases are fundamentally arranged, so people expect the appearance of novel treatment swine escherichia coli medicine.

Summary of the invention

The present invention is in order to overcome deficiency of the prior art, for pig industry provides a kind of curative effect outstanding, and Chinese medicine composition of no drug residue, the treatment colibacillosis of pigs that has no side effect, have no drug resistance and preparation method thereof.

The present invention is achieved through the following technical solutions for achieving the above object, and a kind of Chinese medicine composition for the treatment of colibacillosis of pigs is characterized in that: be made up of following medicine, by weight meter (part)

Radix Pulsatillae 13-17 part Folium Artemisiae Argyi 8-12 part Fructus Crataegi (parched to brown) 8-12 part

Pericarpium Granati 13-17 part Radix Glycyrrhizae 3-7 part Flos Lonicerae 8-12 part

Fructus Forsythiae 8-12 part Semen phaseoli radiati 13-17 part Pericarpium Citri Reticulatae 8-12 part.

The preparation method of above-mentioned Chinese medicine composition is characterized in that: carry out according to the following steps:

(1) taking by weighing the Radix Pulsatillae, Folium Artemisiae Argyi, Fructus Crataegi (parched to brown), Pericarpium Granati, Radix Glycyrrhizae, Flos Lonicerae, Fructus Forsythiae, Semen phaseoli radiati and Pericarpium Citri Reticulatae by weight is raw material

(2) Radix Pulsatillae, Folium Artemisiae Argyi, Fructus Crataegi (parched to brown), Pericarpium Granati, Radix Glycyrrhizae, Flos Lonicerae, Fructus Forsythiae, Semen phaseoli radiati, Pericarpium Citri Reticulatae are pulverized, sieved, make granularity reach the 60-200 order, mix homogeneously, packing gets product.

The said components medicine is commercially available product, meets the relevant regulations of " Chinese veterinary drug allusion quotation ".

Composition principle of the present invention:

The Radix Pulsatillae: have clearing away heat and cooling blood, the antidotal effect is mainly used in and controls toxic-heat and blood stasis, the pyrexial malaria cold and heat, and meridian distribution of property and flavor, hardship, cold.Return stomach, large intestine channel.

Folium Artemisiae Argyi: have the blood of regulating the flow of vital energy, by cold-damp; Warming the meridian, the hemostatic effect, be mainly used in the treatment deficiency and coldness hemorrhage, dispersing cold for relieving pain.Hot, bitter, temperature; Slightly poisonous.Return the liver,spleen,kidney warp.

Fructus Crataegi (parched to brown): sour in the mouth, sweet, slightly warm in nature.The energy invigorating the stomach and promoting digestion, blood circulation promoting and blood stasis dispelling.Various dysentery bacteriums and bacillus pyocyaneus, escherichia coli, golden yellow coccus, anthrax bacillus etc. all have the obvious suppression effect; So can be used for the treatment of bacillary dysentery.

Pericarpium Granati: have astringing intestine to stop diarrhea, hemostasis, anthelmintic effect contains tannin 10.4～21.3%.Sour and astringent, temperature, poisonous, go into large intestine, kidney channel.

Radix Glycyrrhizae: have invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.Meridian distribution of property and flavor: property is flat, flavor is sweet, is mainly used in the treatment weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, cushion toxicity.Be the Chinese medicine of QI invigorating strengthening the spleen simply, have the effect of healthy energy in the accent.

Flos Lonicerae: the main pharmacodynamics composition is a chlorogenic acid, Flos Lonicerae is cold in nature, sweet in the mouth, gas flat, effect with heat-clearing and toxic substances removing is a monarch drug at these combination species, with the Radix Scutellariae compatibility, can treat acute upper respiratory tract infection, acute pharyngolaryngitis, also how treat the infection that above-mentioned pathogenic microorganism causes clinically with it.Flos Lonicerae contains cyclohexanhexanol, flavonoid, inositol, Saponin and tannin etc., has broad-spectrum antibacterial action, various pathogens such as staphylococcus aureus, dysentery bacterium all there is stronger inhibitory action, multiple pathogenic microorganisms such as leptospira, influenza virus and pathogenic moulds are also had inhibitory action.In addition, Flos Lonicerae also has tangible antiinflammatory and refrigeration function.Recently research points out that Flos Lonicerae can promote lymphocytic conversion, and lymhocyte transformation rate can reflect cellular immune function, i.e. human body immunity improving power.Flos Lonicerae can also strengthen leukocytic phagocytic function, improves immunologic function from another angle;

Fructus Forsythiae: have heat clearing away, detoxifcation, eliminating stagnation, repercussive effect.Meridian distribution of property and flavor, hardship, cold.Go into the heart, liver, gallbladder meridian.Contain multiple chemical compounds such as forsythin, phillygenin.

Semen phaseoli radiati: have clearing away heat and removing summer; Diuretic; The antidotal effect is mainly used in the summer-heat excessive thirst; Cold, fever; Cholera is vomited and diarrhoea; The expectorant asthma of heat type is breathed heavily; The headache conjunctival congestion; Aphtha of the mouth and tongue; The edema oliguria; The skin infection carbuncle; The rubella erysipelas; Medicine and alimentary toxicosis.

Pericarpium Citri Reticulatae: have regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, the effect of diuretic relieving constipation.Be mainly used in the treatment incoordination between the spleen and stomach, fullness in the epigastrium and chest, lack of appetite and vomiting; Accumulation of phlegm-damp in the lung, cough with copious phlegm, chest and diaphragm is full vexed, the vertigo;

Edema, dysuria, constipation; Meridian distribution of property and flavor hardship, suffering, temperature.Return lung, spleen channel.

Beneficial effect: prescription is based on traditional Chinese veterinary medicine to pathogenetic cognition of colibacillosis of pigs and Therapeutic Principle, according to the etiology and pathogenesis of colibacillosis of pigs.The Radix Pulsatillae, Flos Lonicerae, the Fructus Forsythiae of blood system, heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery are gone into by the side with bitter cold; The hemostasis of Pericarpium Granati astringing intestine to stop diarrhea, Pericarpium Citri Reticulatae, Semen phaseoli radiati, Folium Artemisiae Argyi is regulated the flow of vital energy, spleen invigorating, diuretic, each component of Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription plays heat-clearing and toxic substances removing jointly, dampness, the effect of inducing diuresis to remove edema.Can not develop immunity to drugs, particularly pig is taken noresidue in the body of back, and then can ensure the edible safety problem of people to meat product effectively.

The specific embodiment

Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:

Embodiment 1

A kind of Chinese medicine composition for the treatment of colibacillosis of pigs is made up of following medicine, counts by weight (part),

Every part by 10g, commercially available Radix Pulsatillae 150g, Folium Artemisiae Argyi 80g, Fructus Crataegi (parched to brown) 80g, Pericarpium Granati 130g, Radix Glycyrrhizae 30g, Flos Lonicerae 120g, Fructus Forsythiae 120g, Semen phaseoli radiati 170g, Pericarpium Citri Reticulatae 120g are pulverized, sieve, make granularity reach 60 orders, mix homogeneously, packing gets product.

Embodiment 2

A kind of Chinese medicine composition for the treatment of colibacillosis of pigs is made up of following medicine, by weight meter (part)

Every part by 10g, commercially available Radix Pulsatillae 170g, Folium Artemisiae Argyi 100g, Fructus Crataegi (parched to brown) 120g, Pericarpium Granati 170g, Radix Glycyrrhizae 70g, Flos Lonicerae 80g, Fructus Forsythiae 80g, Semen phaseoli radiati 130g, Pericarpium Citri Reticulatae 80g are pulverized, sieve, make granularity reach 160 orders, mix homogeneously, packing gets product.

Embodiment 3

A kind of Chinese medicine composition for the treatment of colibacillosis of pigs is made up of following medicine, by weight meter (part)

Every part by 10g, commercially available Radix Pulsatillae 130g, Folium Artemisiae Argyi 120g, Fructus Crataegi (parched to brown) 100g, Pericarpium Granati 150g, Radix Glycyrrhizae 50g, Flos Lonicerae 100g, Fructus Forsythiae 100g, Semen phaseoli radiati 150g, Pericarpium Citri Reticulatae 100g are pulverized, sieve, make granularity reach 200 orders, mix homogeneously, packing gets product.

During use, can mix thoroughly and feed, logotype 3～7 days according to the ratio of 100 kilograms of per 200 grams finished product mix fodders of the present invention.

Clinical trial:

Experimental example 1:

The pig of Shandong Province Lee raiser raising, normal during the piglet birth, first sick pig took place in the nest, brood pig phase secondary disease in a couple of days on 7th in the birth back.Be initially unexpected diarrhoea, discharge thin as the water sample yellow to lark feces, be mixed with minute bubbles and band is stench, diarrhoea is serious further subsequently, promptly rushes down once in several minutes.Thirsty, the dehydration of sick pig, but do not have the vomiting phenomenon, stupor is dead at last.Cut open inspection as seen: corpse dehydration and show skinny and wizened, it is pale to show as xerosis cutis, shrinkage, oral cavity, and anus speckles with yellow loose stool on every side.The acute catarrhal inflammation of intestinal, duodenum is the most serious.Gastric distension, inside are full of the smelly ziega of acid, stomach bottom mucosa flushing.The intestinal wall attenuation, mucosa and serous coat hyperemia, edema are full of stench yellow, the thin content of yellow-white in the enteric cavity.Backlash intestinal distension gas is very remarkable, is diagnosed as colibacillosis.Use this invention finished product 200 grams, mix fodder 200kg, logotype 3 days, feed intake increases to some extent, and feces is normal, uses 2 days again, transference cure, the course of disease is controlled.

Experimental example 2:

18 age in days pigs, sudden onset are raised in the pig farm, Hebei.Sick pig is suffered from diarrhoea suddenly, discharges white, canescence so that yellow medicated porridge shape has special stench glutinous greasy feces, and hogback is slow in action, and fur is coarse unglazed, unclean.Cut open the inspection gastric a small amount of ziega is arranged.The hyperemia of part intestinal mucosa, intestinal wall attenuation and be with translucently, intestinal mucosa easily strips off, and acoprosis contains a large amount of gases and thin on a small quantity, HUANGBAI(sic) colour band acid smell feces.The mesenteric lymph node edema.Be diagnosed as colibacillosis.Use this invention finished product 200 grams, mix fodder 200kg carries out the environment spraying disinfection with the disinfectant solution that contains Operand simultaneously.Medication does not have dead after four days, it is normal that swinery recovers substantially.

The above only is preferred embodiment of the present invention, is not structure of the present invention is done any pro forma restriction.Every foundation technical spirit of the present invention all still belongs in the scope of technical scheme of the present invention any simple modification, equivalent variations and modification that above embodiment did.

Claims (2)

1. a Chinese medicine composition for the treatment of colibacillosis of pigs is characterized in that: be made up of following medicine, by weight meter (part)

Radix Pulsatillae 13-17 part Folium Artemisiae Argyi 8-12 part Fructus Crataegi (parched to brown) 8-12 part

Pericarpium Granati 13-17 part Radix Glycyrrhizae 3-7 part Flos Lonicerae 8-12 part

Fructus Forsythiae 8-12 part Semen phaseoli radiati 13-17 part Pericarpium Citri Reticulatae 8-12 part.

2. the preparation method of an above-mentioned Chinese medicine composition is characterized in that: carry out according to the following steps:

(1) taking by weighing the Radix Pulsatillae, Folium Artemisiae Argyi, Fructus Crataegi (parched to brown), Pericarpium Granati, Radix Glycyrrhizae, Flos Lonicerae, Fructus Forsythiae, Semen phaseoli radiati and Pericarpium Citri Reticulatae by weight is raw material;

(2) Radix Pulsatillae, Folium Artemisiae Argyi, Fructus Crataegi (parched to brown), Pericarpium Granati, Radix Glycyrrhizae, Flos Lonicerae, Fructus Forsythiae, Semen phaseoli radiati, Pericarpium Citri Reticulatae are pulverized, sieved, make granularity reach the 60-200 order, mix homogeneously, packing gets product.