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CN101648153B - Method and special device for automatically identifying suction/discharge mechanism range of electronic pipette - Google Patents

Method and special device for automatically identifying suction/discharge mechanism range of electronic pipette Download PDF

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Publication number
CN101648153B
CN101648153B CN2009100409313A CN200910040931A CN101648153B CN 101648153 B CN101648153 B CN 101648153B CN 2009100409313 A CN2009100409313 A CN 2009100409313A CN 200910040931 A CN200910040931 A CN 200910040931A CN 101648153 B CN101648153 B CN 101648153B
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China
Prior art keywords
control module
piston
electronic liquid
detection
drive unit
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Expired - Fee Related
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CN2009100409313A
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CN101648153A (en
Inventor
吕志荣
郑得胜
史龙
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HANGZHOU KRONO MEDICAL TECHNOLOGY CO LTD
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Individual
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Abstract

The invention discloses a method and a special device for automatically identifying suction/discharge mechanism range of an electronic pipette. A cavity of the electronic pipette is provided with a checking control unit, a stepping drive unit, a reciprocating motion unit and a reciprocating terminating point. Whether the suction/discharge mechanism range of the electronic pipette is the one required by users can be effectively judged by detecting movement distance and movement time of a piston through the inside computer programming, without an additional detecting instrument, which saves the time of users.

Description

Be used for electronic liquid trasferring device and discern the method and the isolated plant of suction/row mechanism range automatically
Technical field
The present invention relates to a kind of method and isolated plant that electronic liquid trasferring device is discerned suction/row mechanism range automatically that be used for, can discern the range of the absorption/output mechanism of electronic liquid trasferring device automatically.The meter electronics tool field that belongs to accurate transfer liquid.
Background technology
Electronic liquid trasferring device is to be used for accurate liquid sample or the reagent that shifts certain volume.Electronic liquid trasferring device is formed by detecting control system and absorption/discharge system usually; Wherein, detect the control system and be made up of stepper motor, step actuator, motor detecting controller etc., absorption/discharge system is made up of piston, piston cylinder and disposable suction nozzle; The one or more pistons that detect in the stepper motor drive absorption/discharge system in the control system control sytsem move back and forth in piston cylinder; Reciprocating motion through piston changes the air containment in the piston cylinder, thus the soakage or the discharge rate of control liquid.Because it is increasingly high in the modern laboratory to the data demand of being gathered; To experiment reagent to take required precision also increasingly high; Plunger shaft space size has very big influence to taking the caused error of reagent to the precision of electronic liquid trasferring device; Therefore, select the electronic liquid trasferring device of the most approaching piston cylinder of the liquid volume that has and desire to take for use, can avoid the error that causes because of plunger shaft space size to a great extent; So just require to dispose when a series of electronic liquid trasferring devices with absorption/output mechanism of different ranges pipette liquid volume for difference and use, still can increase the manufacturing cost and the use cost of electronic liquid trasferring device greatly.
In the prior art, the someone repays the electronic liquid trasferring device that tries to utilize a detection control system to control the absorption/output mechanism of several different ranges and addresses the above problem.But the electronic liquid trasferring device of this type all is after changing different range absorption/output mechanisms in use at present, and operation detection is controlled system's metering-in control system menu again, to the corresponding execution pattern of the measurement range selection of being changed.For using the unskilled user of electronic liquid trasferring device, through regular meeting mistake taking place to select, with not operating with the execution pattern that the absorption of using/the output mechanism range is corresponding, thereby has caused that the test manufacture data are forbidden or the damage of pipettor like this.And; Because the switch step that moves the liquid pattern of electronic liquid trasferring device is comparatively complicated, the setting of user interface comparatively bothers with operation; The user is in practical operation is used; Without the study procedure of adaptation of complicacy, usually in setting and application process, being provided with of corresponding operating confused, hindered the extensive use of electronic liquid trasferring device.
Summary of the invention
One of the object of the invention; Be in order to solve electronic liquid trasferring device in practical operation; After electronic liquid trasferring device is changed different range absorption/output mechanisms; Shortcomings such as the switch step complicacy of operator scheme, troublesome poeration and easy generation operating mistake provide a kind of method that electronic liquid trasferring device is discerned suction/row mechanism range automatically that is used for.
Two of the object of the invention is for a kind of isolated plant that electronic liquid trasferring device is discerned suction/row mechanism range automatically that is used for is provided.
One of the object of the invention, mainly realize through following technical scheme:
Be used for electronic liquid trasferring device and discern the method for suction/row mechanism range automatically, it is characterized in that, comprise following step:
1) by the detection of electronic liquid trasferring device and the reciprocating motion of control module monitoring piston; The stepper drive cell operation electric current of the variation causes electrons pipettor of this reciprocating motion of the pistons state changes, with feeding back to the detection of electronic liquid trasferring device and the feedback input end of control module after the conversion of operating current variable signal;
2) by detecting and control module control step drive unit drives piston reciprocates; Pass through to measure the numerical value change of feedback signal by said detection and control module; When this feedback signal significantly increases suddenly or significantly reduces suddenly, judge piston arrives forward terminating point;
3) when said piston motion arrives the forward terminating point; By detecting and control module responds the 2nd) the feedback data information in step; Distance and activity time that opening entry piston or stepper motor are movable; And at first send to the stepper drive unit and stop positive movement instruction, send the counter motion instruction then;
4) after the stepper drive unit receives the counter motion instruction; Driven plunger is to motion in the other direction; Stop in the other direction and when stopping, the operating current of stepper drive unit takes place sharply to change when piston runs into, promptly sharply become big or diminish; The rapid variable signal of this electric current feeds back to the detection of electronic liquid trasferring device and the feedback input end of control module after conversion, detect and the reverse terminating point of control module judgement piston arrives;
5) when the motion of said piston arrives reverse terminating point, by detecting and control module responds the 4th) the feedback data information in step, send halt instruction to the stepper drive unit immediately, stop movable distance of recording and analyses or stepper motor and movable time simultaneously;
6) presetting definite value by the data of said detection and the control module distance that the piston of record or stepper motor is movable and activity time with the absorption/output mechanism of various different ranges compares; Find out the one group of preset definite value that equates with the data and the data of activity time of the distance of piston that writes down or stepper motor; Then judge the i.e. preset definite value of group for this reason of range of the absorption/output mechanism of this electronic pipetting device, detect and control module can get into corresponding therewith operator scheme, working interface or next operation sequence automatically.
A kind of embodiment that realizes the present invention's first purpose is: said stepper drive unit is made up of step actuator and stepper motor.
A kind of embodiment that realizes the present invention's first purpose is: the aforementioned the 1st) step and the 4th), the control instruction that detection and control module send is reciprocating with the current constant mode driven plunger through the stepper drive unit.
A kind of embodiment that realizes the present invention's first purpose is: this is the method for identification suction/row mechanism range automatically; Accomplish by the control program that is built in electronic pipettor; When each electronic liquid-transfering device is changed the absorption of different ranges/output mechanism, start and discern, perhaps access program start at any time and discern by the user.
A kind of embodiment that realizes the present invention's first purpose is: when the user was provided with the operation of the absorption/output mechanism range that surpasses electronic liquid trasferring device, detection and control module can in time be pointed out error message on display screen.
Two of the object of the invention, mainly realize by the following technical programs:
Be used for electronic liquid trasferring device and discern the isolated plant of suction/row mechanism range automatically, comprise electronic liquid trasferring device, its design feature is: the inner chamber at electronic liquid trasferring device is provided with detection and control module, stepper drive unit, moves back and forth the unit and moves back and forth terminating point; Moving back and forth the unit moves in moving back and forth the terminating point restricted portion; The signal output part of detection and control module connects the control signal input of stepper drive unit; The signal output part of stepper drive unit connects signal input part, the feedback signal output joint detection of stepper drive unit and the feedback signal input of control module that moves back and forth the unit.
An embodiment that realizes second purpose of the present invention is: the detecting controller of electronic liquid trasferring device constitutes detection and control module; Step actuator and stepper motor constitute the stepper drive unit; Piston and piston cylinder constitute the reciprocating motion unit; The stop member of installing on the two ends inwall of piston cylinder or the two ends inwall constitutes the reciprocating motion terminating point.
Operation principle of the present invention is following:
Piston moves reciprocatingly in piston cylinder, because the diameter of the piston cylinder of different ranges and piston is different, distance and time that piston moves between the starting point of piston cylinder and terminating point are all inequality., piston causes stepper motor stall when moving to the stopping of terminating point and starting point at piston cylinder two ends; The electric current that motor stall makes detection and control module supply with motor takes place to change suddenly; The variation of follow current; Movable distance and the movable time of piston in the time of can detecting piston and run into piston cylinder two ends terminating point and starting point, thus judge the range of corresponding with it plunger shaft, i.e. the absorption of electronic liquid trasferring device/discharge system range.
The beneficial effect that the present invention has is following:
1, the present invention; Need not to add in addition detecting instrument; Only through the structure member in the existing electronic liquid trasferring device, through built-in computer program design, to the move distance of piston and the detection of run duration; Thereby whether absorption/discharge system range of effectively judging the electronic liquid trasferring device that it used is the absorption/discharge system range of the electronic liquid trasferring device of user oneself needs, for the user has saved the time.
2, adopt the present invention; Make electronic liquid trasferring device have automatic identification absorption/discharge system range function; After can overcoming the prior art electronic liquid trasferring device and changing different range absorption/output mechanisms; Shortcomings such as the switch step complicacy of operator scheme, troublesome poeration and easy generation operating mistake can avoid some to surpass the generation of the faulty operation of range.
Description of drawings
Fig. 1 is the structural representation of specific embodiment 1 plunger shaft.
Fig. 2 is the structural representation of specific embodiment 2 plunger shaft.
Specific embodiment
Specific embodiment 1
Fig. 1 constitutes specific embodiment 1 of the present invention.
Inner chamber at electronic liquid trasferring device is provided with control module, stepper drive unit, moves back and forth the unit and moves back and forth terminating point; Moving back and forth the unit moves in moving back and forth the terminating point restricted portion; The signal output part of detection and control module connects the control signal input of stepper drive unit; The signal output part of stepper drive unit connects signal input part, the feedback signal output joint detection of stepper drive unit and the feedback signal input of control module that moves back and forth the unit.
In the present embodiment, the detection of electronic liquid trasferring device and control module comprise the detecting controller; Step actuator and stepper motor constitute the stepper drive unit; Piston and piston cylinder constitute the reciprocating motion unit; The two ends inwall of piston cylinder constitutes the reciprocating motion of the pistons terminating point.
In electronic liquid trasferring device; Utilize above-mentioned device to discern the method for suction/row mechanism range automatically; Mainly comprise following step: 1) detection of electronic liquid trasferring device and control module send the instruction of stepper motor 1 positive movement to step actuator, and stepper motor 1 promotes piston 2 and moves in piston cylinder 3 with current constant mode; 2) when piston 2 moves to the inwall 3-1 of piston cylinder 3, the drive current of stepper motor 1 is owing to receive the rapid variation that stops of piston cylinder inwall 3-1, the change-over circuit of motor detecting this moment controller in time converts situation to the data message feedback; 3) detection and control module responsive feedback information send out stepper motor 1 to step actuator immediately and stop positive movement and the instruction that runs back, and opening entry piston or movable distance and activity time of stepper motor; 4) after step actuator receives the counter motion instruction; Drive stepping motor 1 is being drawn piston 2 to motion in the other direction; When the inwall that moves to reciprocal piston cylinder 3 when piston 2 stops; The drive current of stepper motor 1 sharply changes, and the detecting controller is judged the reverse terminating point of piston arrives, and this current changing signal feeds back to the detection of electronic liquid trasferring device and the feedback input end of control module after conversion; 5) detection and control module responsive feedback data message send halt instruction to the stepper drive unit immediately, stop movable distance of recording and analyses or stepper motor and movable time simultaneously; 6) detection and control module compare the data and the data of activity time of the distance of piston that writes down or stepper motor activity with the preset definite value of the absorption/discharge system program of different ranges; One group of preset definite value that the data of the distance that the stepper motor of finding out and writing down is movable and the data of activity time equate; Then judge the i.e. preset definite value of group for this reason of range of the absorption/discharge system of this electronic pipetting device, detect and control module can get into corresponding therewith operator scheme, working interface or next operation sequence automatically.
This trace routine can start and discern when each electronic liquid-transfering device changed the absorption of various different ranges/discharge system, also can access program start at any time by the user and discern.When the user was provided with the operation of the absorption/discharge system range that surpasses electronic liquid trasferring device, detection and control module can in time be pointed out error message on display screen.
Specific embodiment 2
As shown in Figure 2, the characteristics of present embodiment are: two stop member 3-2 are installed as piston 2 reciprocating forward terminating points and reverse terminating point on the inwall of the two ends of piston cylinder 3; Space between the stop member 3-2 of piston cylinder two ends is the range of piston cylinder.All the other are identical with specific embodiment 1.

Claims (6)

1. be used for electronic liquid trasferring device and discern the method for suction/row mechanism range automatically, it is characterized in that, comprise following step:
1) by the detection of electronic liquid trasferring device and the reciprocating motion of control module monitoring piston (2); The stepper drive cell operation electric current that this piston (2) moves back and forth the variation causes electrons pipettor of state changes, with feeding back to the detection of electronic liquid trasferring device and the feedback input end of control module after the conversion of operating current variable signal;
2) reciprocating by detection and control module control step drive unit drives piston (2); Pass through to measure the numerical value change of feedback signal by said detection and control module; When this feedback signal significantly increases suddenly or significantly reduces suddenly, judge that piston (2) arrives the forward terminating point;
3) when said piston (2) motion arrives the forward terminating point; By detecting and control module responds the 2nd) the feedback data information in step; Distance and activity time that opening entry piston (2) or stepper motor (1) are movable; And at first send to the stepper drive unit and stop positive movement instruction, send the counter motion instruction then;
4) after the stepper drive unit receives the counter motion instruction; Driven plunger (2) is to motion in the other direction; Stop in the other direction and when stopping, the operating current of stepper drive unit takes place sharply to change when piston (2) runs into, promptly sharply become big or diminish; The rapid variable signal of this electric current feeds back to the detection of electronic liquid trasferring device and the feedback input end of control module after conversion, detection and control module judge that piston (2) arrives reverse terminating point;
5) when said piston (2) motion arrives reverse terminating point; By detecting and control module responds the 4th) the feedback data information in step; Send halt instruction to the stepper drive unit immediately, stop movable distance of recording and analyses (2) or stepper motor and movable time simultaneously;
6) presetting definite value by the data of said detection and the control module distance that the piston (2) of record or stepper motor (1) is movable and activity time with the absorption/output mechanism of various different ranges compares; Find out the one group of preset definite value that equates with the data and the data of activity time of the distance of piston that writes down (2) or stepper motor (1); Then judge the i.e. preset definite value of group for this reason of range of the absorption/output mechanism of this electronic pipetting device, detect and control module can get into corresponding therewith operator scheme, working interface or next operation sequence automatically.
2. according to claim 1ly be used for the method that electronic liquid trasferring device is discerned suction/row mechanism range automatically, it is characterized in that: said stepper drive unit is made up of step actuator and stepper motor (1).
3. according to claim 1ly be used for the method that electronic liquid trasferring device is discerned suction/row mechanism range automatically; It is characterized in that: the aforementioned the 1st) step and the 4th), the control instruction that detection and control module send is reciprocating with current constant mode driven plunger (2) through the stepper drive unit.
4. according to claim 1ly be used for the method that electronic liquid trasferring device is discerned suction/row mechanism range automatically; It is characterized in that: this is the method for identification suction/row mechanism range automatically; Accomplish by the control program that is built in electronic pipettor; When each electronic liquid-transfering device is changed the absorption of different ranges/output mechanism, start and discern, perhaps access program start at any time and discern by the user.
5. according to claim 1ly be used for the method that electronic liquid trasferring device is discerned suction/row mechanism range automatically; It is characterized in that: when the user was provided with the operation of the absorption/output mechanism range that surpasses electronic liquid trasferring device, detection and control module can in time be pointed out error message on display screen.
6. use the isolated plant that electronic liquid trasferring device is discerned suction/row mechanism range automatically that is used for of the method for claim 1, comprise electronic liquid trasferring device, it is characterized in that:
1) inner chamber at electronic liquid trasferring device is provided with detection and control module, stepper drive unit, moves back and forth the unit and moves back and forth terminating point; Moving back and forth the unit moves in moving back and forth the terminating point restricted portion; The signal output part of detection and control module connects the control signal input of stepper drive unit; The signal output part of stepper drive unit connects the signal input part that moves back and forth the unit, the feedback signal output joint detection of stepper drive unit and the feedback signal input of control module;
2) the detecting controller of electronic liquid trasferring device constitutes detection and control module; Step actuator and stepper motor (1) constitute the stepper drive unit; Piston (2) and piston cylinder (3) constitute the reciprocating motion unit; The stop member of installing on the two ends inwall (3-1) of piston cylinder (3) or the two ends inwall (3-2) constitutes the reciprocating motion terminating point.
CN2009100409313A 2009-07-08 2009-07-08 Method and special device for automatically identifying suction/discharge mechanism range of electronic pipette Expired - Fee Related CN101648153B (en)

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CN2009100409313A CN101648153B (en) 2009-07-08 2009-07-08 Method and special device for automatically identifying suction/discharge mechanism range of electronic pipette

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Application Number Priority Date Filing Date Title
CN2009100409313A CN101648153B (en) 2009-07-08 2009-07-08 Method and special device for automatically identifying suction/discharge mechanism range of electronic pipette

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CN101648153B true CN101648153B (en) 2012-03-28

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CN106706945B (en) * 2016-12-30 2018-12-21 无锡博慧斯生物医药科技有限公司 A kind of reagent automatic dripping device and the portable tester using the device
CN108414288B (en) * 2018-03-11 2021-02-05 北京工业大学 Sampling structure suitable for flexible raking device

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Owner name: HANGZHOU KENUO MEDICAL TECHNOLOGY CO., LTD.

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Address after: Hangzhou City, Zhejiang province 311202 Xiaoshan Qianjiang farm (Transfar technology city)

Patentee after: Hangzhou Krono Medical Technology Co.,Ltd.

Address before: 510540 863 industrialization promotion center of Taihe private science and Technology Park, Baiyun District, Guangdong, Guangzhou 6F

Patentee before: Lv Zhirong

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