CN101569600A - Antibacterial traditional Chinese medicine additive for bath lotion and preparation method thereof - Google Patents
Antibacterial traditional Chinese medicine additive for bath lotion and preparation method thereof Download PDFInfo
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Abstract
本发明涉及来源于植物的洗浴添加剂,具体涉及一种用于洗浴乳液具有抗菌抑菌功效的中药添加剂。本发明的中药添加剂由下列重量比的原料组成:苦参10~15、黄莲15~25、艾叶15~20、生姜20~30、薄荷15~20、黄芩20~30、辣椒10~15、侧柏叶15~20、黄柏15~20、雪莲果叶25~30、甘草25~35。本添加剂可以作为洗浴乳液包括洗发乳液、沐浴乳液、洁面乳液、洗手液的添加剂,能够替代化学抑菌剂杀灭抑制粪大肠杆菌、金黄色葡萄球菌、绿脓杆菌等常规细菌和马拉色菌等皮肤真菌,添加至洗浴乳液后具有止痒、灭菌、去屑、护肤的作用,对皮肤不产生刺激和毒副作用,同时具有低成本和不污染环境的优势。The invention relates to a bath additive derived from plants, in particular to a traditional Chinese medicine additive used in bath lotions with antibacterial and antibacterial effects. The traditional Chinese medicine additive of the present invention is composed of the following raw materials in weight ratio: Sophora flavescens 10-15, Coptis chinensis 15-25, Artemisia argyi 15-20, Ginger 20-30, Mint 15-20, Scutellaria baicalensis 20-30, Capsicum 10-15, Arborvitae leaves 15-20, Phellodendron 15-20, Yacon leaves 25-30, Licorice 25-35. This additive can be used as an additive for bath lotion including shampoo lotion, body lotion, facial cleanser, and hand sanitizer, and can replace chemical bacteriostatic agents to kill and inhibit conventional bacteria such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Malassezia Bacteria and other skin fungi, when added to the bath lotion, it has the functions of antipruritic, sterilizing, anti-dandruff, and skin care. It does not cause irritation and side effects to the skin, and has the advantages of low cost and no pollution to the environment.
Description
技术领域 technical field
本发明涉及来源于植物的洗浴添加剂,具体涉及一种用于洗浴乳液具有抗菌抑菌功效的中药添加剂及其制备方法。The invention relates to a bath additive derived from plants, in particular to a traditional Chinese medicine additive used in bath lotion with antibacterial and antibacterial effects and a preparation method thereof.
背景技术 Background technique
洗浴用品在市场上琳琅满目,其作用一是去污,二是兼有保湿、护肤、抑菌等。要达到以上作用可以加入各种添加剂,但大都是化学制剂,对皮肤有一定刺激作用,有些甚至会致敏。用中药添加剂替代化学制剂,副作用小,且保护皮肤。但中药添加于乳液体系中,会使乳液的泡沫、稳定性产生影响,导致这种情况的原因除了与中药添加量有关还与中药成分有关。本发明在中国专利1074114、1131035、1334077、1176099、02129032的基础上,不仅考虑了中药成分对乳液性能的影响,中药添加量以及对粪大肠杆菌、金黄色葡萄球菌、绿脓杆菌等常规细菌和马拉色菌等皮肤真菌的有效抑制及杀灭作用。以上提到的专利基本是一些中药组合或是组合后的提取物直接用于洗浴,这样的浴液只是一种中药液,而达不到同时去污洗涤的目的。There are a lot of bath products on the market, and their functions are decontamination, moisturizing, skin care, antibacterial and so on. Various additives can be added to achieve the above effects, but most of them are chemical agents, which have a certain stimulating effect on the skin, and some may even cause sensitization. The traditional Chinese medicine additive is used to replace the chemical preparation, the side effect is small, and the skin is protected. However, the addition of traditional Chinese medicine to the emulsion system will affect the foam and stability of the emulsion. The reason for this situation is not only related to the amount of traditional Chinese medicine added but also to the ingredients of traditional Chinese medicine. On the basis of Chinese patents 1074114, 1131035, 1334077, 1176099, and 02129032, the present invention not only considers the influence of traditional Chinese medicine ingredients on the performance of the emulsion, but also the amount of Chinese medicine added and the effects on conventional bacteria such as E. Effective inhibition and killing of skin fungi such as Malassezia. The patents mentioned above are basically that some Chinese medicine combinations or the combined extracts are directly used for bathing. Such bath liquid is only a kind of Chinese medicine liquid, and cannot reach the purpose of decontamination and washing at the same time.
发明内容 Contents of the invention
本发明的目的是提供一种用于洗浴乳液的抗菌中药添加剂及其制备方法,该添加剂充分考虑了中药有效成分的作用,同时考虑了对洗浴乳液体系的性能的影响,能有效抑制及杀灭粪大肠杆菌、金黄色葡萄球菌、绿脓杆菌等常规细菌和马拉色菌等皮肤真菌。The object of the present invention is to provide a kind of antibacterial traditional Chinese medicine additive for bath lotion and its preparation method, and this additive fully considers the effect of active ingredient of traditional Chinese medicine, simultaneously considers the impact on the performance of bath lotion system, can effectively inhibit and kill Common bacteria such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and skin fungi such as Malassezia.
本发明通过以下技术技术方案实现:The present invention is realized through the following technical solutions:
本中药添加剂的各组分重量之比为,苦参(10~15)、黄莲(15~25)、艾叶(15~20)、生姜(20~30)、薄荷(15~20)、黄芩(20~30)、辣椒(10~15)、侧柏叶(15~20)、黄柏(15~20)、雪莲果叶(25~30)、甘草(25~35)。The weight ratio of each component of this traditional Chinese medicine additive is: Sophora flavescens (10-15), Huanglian (15-25), Artemisia argyi (15-20), Ginger (20-30), Peppermint (15-20), Scutellaria baicalensis (20-30), pepper (10-15), arborvitae leaves (15-20), cork (15-20), yacon leaves (25-30), licorice (25-35).
本中药添加剂的制备工艺包括:(1)按配方量将生姜、薄荷、黄芩用10~15倍重量百分比60~80%乙醇回流提取2次,合并滤液,静置7天后过滤备用,回收乙醇;(2)药渣与苦参、黄莲、艾叶、侧柏叶、黄柏、雪莲果叶、甘草一起加10~15倍水煎煮2次,合并滤液,静置7天后过滤备用;(3)将前面二步骤得到的滤液混合搅拌均匀,静置3天后过滤备用;(4)根据需要进行浓缩成浸膏或喷雾干燥成干粉。The preparation process of the traditional Chinese medicine additive includes: (1) refluxing and extracting ginger, peppermint and scutellaria baicalensis with 10 to 15 times the weight percentage of 60 to 80% ethanol according to the formula amount twice, combining the filtrates, filtering after standing for 7 days, and recovering the ethanol; (2) Add 10-15 times of water to decoct the medicinal residues together with Sophora flavescens, Coptis chinensis, Artemisia argyi leaves, Arborvitae leaves, Phellodendron japonica, yacon leaves, and licorice for 2 times, combine the filtrates, let stand for 7 days, and then filter for later use; (3) Mix and stir the filtrate obtained in the previous two steps evenly, and filter after standing for 3 days for later use; (4) Concentrate into extract or spray dry into dry powder as required.
在本发明所述的中药添加剂的制备工艺中,当添加于洗浴乳液产品中,浸膏添加量控制在1~5%,干粉控制在0.5~3%,既不会影响洗浴产品的泡沫高度和乳液的稳定性,又能较好抑制和杀灭粪大肠杆菌、金黄色葡萄球菌、绿脓杆菌等常规细菌和马拉色菌等皮肤真菌。In the preparation process of the traditional Chinese medicine additive described in the present invention, when added to the bath lotion product, the addition amount of the extract is controlled at 1-5%, and the dry powder is controlled at 0.5-3%, which will neither affect the foam height and The stability of the emulsion can better inhibit and kill conventional bacteria such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and skin fungi such as Malassezia.
本发明利用天然的具有多种抑菌、保湿、护肤、清凉等作用的中药为原料,配以:苦参,具有清热燥湿、杀虫、利尿等功效,治皮肤瘙痒,阴疮湿痒,烫伤,疥癣麻疹等作用;黄莲,具有明显的广谱抗菌性,对革兰氏阳性与阴性菌、金黄色葡萄球菌等有较强的抗菌作用;艾叶,具有抗菌抗病毒、止血与抗凝血、抗过敏等作用;生姜,具有解表散寒、温中止呕,抗氧化,延缓神经病变性疾病的发生与发展,对抗体内或体外血管生成,治疗高血压和心动过速,具抗微生物活性;薄荷,具有抗病毒、抗菌包括对大肠杆菌、表面葡萄球菌、须毛癣菌等有较强抗菌作用,杀虫除螨,促进作用,可有效促进药物透过皮肤的吸收,同时具有抗氧化、抗辐射作用;黄芩,具有抑制大肠杆菌、枯草杆菌、白念珠菌、金黄色葡萄球菌等,同时具有抗炎、抗过敏、抗氧化和清除自由基作用;辣椒,具有治疗皮肤病及皮肤瘙痒症,同时对蜡样芽胞杆菌及枯草杆菌有较强抑制作用;侧柏叶,具有抗炎及抗真菌作用,治疗疱疹,止血抑菌等;黄柏,具有清热燥湿、泻火解毒、消肿祛腐作用;雪莲果叶具有抗菌、抗氧化和清除自由基作用;甘草,具有抗炎、抗病毒、保湿的作用。洗浴液中使用这些中药组合物具有较强的抗病毒、抗菌、抑菌、养颜、护肤等功效,对具有皮肤疾病的群体有一定疗效及缓解。The present invention uses natural traditional Chinese medicines with multiple antibacterial, moisturizing, skin care, and cooling effects as raw materials, and is equipped with Sophora flavescens, which has the effects of clearing away heat and dampness, killing insects, diuresis, etc. Scalds, scabies and measles, etc.; Huanglian has obvious broad-spectrum antibacterial properties, and has strong antibacterial effects on Gram-positive and negative bacteria, Staphylococcus aureus, etc.; Blood coagulation, anti-allergy and other effects; Ginger has the functions of relieving the exterior and dispelling cold, warming the middle and relieving vomiting, anti-oxidation, delaying the occurrence and development of neuropathic diseases, resisting angiogenesis in vivo or in vitro, treating hypertension and tachycardia, and having anti-microbial properties Active; peppermint, antiviral, antibacterial, including strong antibacterial effect on Escherichia coli, surface staphylococcus, trichophyton mentagrophytes, etc. Oxidation and anti-radiation effects; Scutellaria baicalensis, which can inhibit Escherichia coli, Bacillus subtilis, Candida albicans, Staphylococcus aureus, etc., and has anti-inflammatory, anti-allergic, anti-oxidation and free radical scavenging effects; Capsicum, has the effect of treating skin diseases and skin Pruritus, at the same time has a strong inhibitory effect on Bacillus cereus and Bacillus subtilis; orientalis leaves, has anti-inflammatory and anti-fungal effects, can treat herpes, stops bleeding and inhibits bacteria, etc.; Swelling and decomposing effect; yacon leaves have antibacterial, anti-oxidation and free radical scavenging effects; licorice has anti-inflammatory, anti-viral and moisturizing effects. These traditional Chinese medicine compositions used in the bath liquid have strong antiviral, antibacterial, antibacterial, beauty, skin care and other effects, and have a certain curative effect and relief for groups with skin diseases.
具体实施方案 specific implementation plan
实施例1Example 1
1.取生姜20份、薄荷15份、黄芩20份用10倍75%乙醇回流提取2次,合并滤液,静置1周后过滤备用,回收乙醇。1. Take 20 parts of ginger, 15 parts of mint, and 20 parts of scutellaria baicalensis, extract twice with 10 times of 75% ethanol under reflux, combine the filtrate, let it stand for 1 week, filter it for later use, and recover the ethanol.
2.取苦参10份、黄莲15份、艾叶15份、、辣椒10份、侧柏叶15份、黄柏15份、雪莲果叶25份、甘草25份与上步提取的药渣加10倍水煎煮2次,合并滤液,静置1周后过滤备用。2. Take 10 parts of sophora flavescens, 15 parts of yellow lotus, 15 parts of mugwort leaves, 10 parts of pepper, 15 parts of arborvitae leaves, 15 parts of Phellodendron cork, 25 parts of yacon fruit leaves, 25 parts of licorice and add 10 parts of the dregs extracted from the previous step. Double the water and decoct twice, combine the filtrate, let it stand for 1 week, and then filter it for later use.
3.将1和2步得到的滤液混合搅拌均匀,静置3天后过滤。3. Mix and stir the filtrate obtained in step 1 and step 2 evenly, let stand for 3 days and then filter.
4.将滤液浓缩至比重为1.15浓缩浸膏。4. The filtrate is concentrated to a specific gravity of 1.15 concentrated extract.
5.将所制添加剂用于洗发水乳液中进行乳液泡沫高高度、稳定性及抑菌试验,其结果见表1、表2。5. The prepared additives are used in shampoo emulsions to carry out emulsion foam height, stability and antibacterial tests, the results are shown in Table 1 and Table 2.
表1 添加中草药添加剂(浸膏)浓度为4%洗发乳液性能Table 1 Adding Chinese herbal medicine additive (extract) concentration is 4% performance of shampoo lotion
表2 中草药添加剂(浸膏)抑菌效果Table 2 Antibacterial effect of Chinese herbal medicine additives (extracts)
注:“+”为阳性,“-”为阴性Note: "+" is positive, "-" is negative
实施例2Example 2
1.取生姜22份、薄荷18份、黄芩23份用15倍65%乙醇回流提取2次,合并滤液,静置1周后过滤备用,回收乙醇。1. Take 22 parts of ginger, 18 parts of mint, and 23 parts of scutellaria baicalensis, extract twice with 15 times of 65% ethanol under reflux, combine the filtrate, let it stand for 1 week, filter it for later use, and recover the ethanol.
2.取苦参13份、黄莲18份、艾叶18份、、辣椒15份、侧柏叶20份、黄柏15份、雪莲果叶30份、甘草25份与上步提取的药渣加13倍水煎煮2次,合并滤液,静置1周后过滤备用。2. Take 13 parts of sophora flavescens, 18 parts of yellow lotus, 18 parts of mugwort leaves, 15 parts of pepper, 20 parts of arborvitae leaves, 15 parts of Phellodendron cork, 30 parts of yacon fruit leaves, 25 parts of licorice and add 13 parts of the dregs extracted in the previous step. Double the water and decoct twice, combine the filtrate, let it stand for 1 week, and then filter it for later use.
3.将1和2步得到的滤液混合搅拌均匀,静置3天后过滤。3. Mix and stir the filtrate obtained in step 1 and step 2 evenly, let stand for 3 days and then filter.
4.将滤液喷雾干燥成干粉。4. Spray-dry the filtrate into a dry powder.
5.将所制添加剂用于洗发水乳液中进行乳液泡沫高高度、稳定性及抑菌试验,其结果见表3、表4。5. The prepared additives are used in shampoo emulsions to carry out emulsion foam height, stability and antibacterial tests, the results are shown in Table 3 and Table 4.
表3添加中草药添加剂(干粉)浓度为1%洗发乳液性能Table 3 adds Chinese herbal medicine additive (dry powder) concentration and is 1% shampoo performance
表2中草药添加剂(干粉)抑菌效果Antibacterial effect of Chinese herbal medicine additive (dry powder) in table 2
注:“+”为阳性,“-”为阴性Note: "+" is positive, "-" is negative
实施例3Example 3
1.取生姜26份、薄荷12份、黄芩20份用15倍80%乙醇回流提取2次,合并滤液,静置1周后过滤备用,回收乙醇。1. Take 26 parts of ginger, 12 parts of mint, and 20 parts of scutellaria baicalensis, extract twice with 15 times of 80% ethanol under reflux, combine the filtrate, let it stand for 1 week, filter it for later use, and recover the ethanol.
2.取苦参15份、黄莲20份、艾叶12份、、辣椒12份、侧柏叶18份、黄柏18份、雪莲果叶28份、甘草30份与上步提取的药渣加15倍水煎煮2次,合并滤液,静置1周后过滤备用。2. Take 15 parts of sophora flavescens, 20 parts of yellow lotus, 12 parts of mugwort leaves, 12 parts of pepper, 18 parts of arborvitae leaves, 18 parts of Phellodendron cork, 28 parts of yacon fruit leaves, 30 parts of licorice and add 15 parts of the dregs extracted from the previous step. Double the water and decoct twice, combine the filtrate, let it stand for 1 week, and then filter it for later use.
3.将1和2步得到的滤液混合搅拌均匀,静置3天后过滤。3. Mix and stir the filtrate obtained in step 1 and step 2 evenly, let stand for 3 days and then filter.
4.将滤液喷雾干燥成干粉。4. Spray-dry the filtrate into a dry powder.
5.将所制添加剂用于洗发水乳液中进行乳液泡沫高高度、稳定性及抑菌试验,其结果见表3、表4。5. The prepared additives are used in shampoo emulsions to carry out emulsion foam height, stability and antibacterial tests, the results are shown in Table 3 and Table 4.
表3添加中草药添加剂(干粉)浓度为1%洗发乳液性能Table 3 adds Chinese herbal medicine additive (dry powder) concentration and is 1% shampoo performance
表2中草药添加剂(干粉)抑菌效果Antibacterial effect of Chinese herbal medicine additive (dry powder) in table 2
注:“+”为阳性,“-”为阴性Note: "+" is positive, "-" is negative
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