CN101549101A - Traditional Chinese medicine for treating pneumoconiosis and drug-tolerant pulmonary tuberculosis and preparation method thereof - Google Patents
Traditional Chinese medicine for treating pneumoconiosis and drug-tolerant pulmonary tuberculosis and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating pneumoconiosis and drug-tolerant pulmonary tuberculosis and a preparation method thereof, which improve and eliminate the pathological residues through the synergy of all medicine according to the dialectic theory of the traditional Chinese medicine, thus leading the body fluid and other organic substances to be transferred to the lung and achieving the effect of rapidly relieving and getting rid of disease and health recovery. The traditional Chinese medicine prepared in the invention comprises the raw materials with weight ratios as follows: 8-12 parts of cordyceps sinensis, 3-7 parts of tokay, 250-350 parts of Pinellia tuberifera, 25-300 parts of Chinese wolfberry, 250-350 parts of Bletilla hyacinthina reichb, 15-50 parts of balloon flower, 3-20 parts of mulberry bark, 3-20 parts of shizandra berry, 250-350 parts of liquorice root, 45-55 parts of bulb of fritillary, 15-25 parts of almond, 15-25 parts of Tatarian Aster Root, 25-35 parts of coltsfoot, 15-25 parts of Blackberrykiky Rhizome, 8-12 parts of root of straight ladybell, 8-12 parts of dried orange peel, 8-12 parts of sugared sesame powder, 10-20 parts of polygala tenuifolia, 8-12 parts of red tangerine peel, 15-25 parts of ginkgo seed, 15-25 parts of trichosanthes kirilowii shell, 15-25 parts of white muscardine silkworm, 8-12 parts of placenta hominis, 4-8 parts of Scutellaria baicalensis, 8-12 parts of radix peucedani, 8-12 parts of perilla seed.
Description
One, technical field:
The present invention relates to a kind of Chinese medicine, specifically be meant a kind of Chinese medicine that is used for the treatment of pneumoconiosis and drug-tolerant pulmonary tuberculosis and preparation method thereof.
Two, background technology:
Pneumoconiosis is owing to causing at the medium-term and long-term industrial dust (as coal dust, breeze, weldering electricity dust etc.) that sucks of activity in production, systemic disease based on the lung tissue diffuse fibrosis, the excessive increase of matter between pulmonary fibrosis, and then the normal lung tissue of broken ring, the elasticity of lung is reduced, influence the normal respiratory function of lung.Because pneumoconiosis does not have special clinical manifestation, early stage pneumosilicosis does not have tangible subjective symptoms or has only slight subjective symptoms, often have only when inspection just can find, but along with further developing of disease when finding, the patient in late period particularly, light or the heavy subjective symptoms based on respiratory system can appear, first symptom is cough, expectoration, hemoptysis, uncomfortable in chest, chest pain, breathe hard, become thin, unable, insomnia, loss of appetite etc., minority merges tuberculosis, often feel to breathe hard when being engaged in heavy physical labour or when excessively walking about when the state of an illness is light, have a rest a little and just can take a turn for the better, lose all labour forces in the time of seriously, quality of life descends, until health risk and life.
At present clinically in treatment to it, doctor trained in Western medicine adopts cleans operation and medicine chemotherapeutic treatment, as aluminium citrate, phosphoric acid croak quinoline, oxypovidinum etc., immune function with enhancing body, but western medical treatment can have certain side effect to human body, and therapeutic effect is not fine, and the traditional Chinese medical science is thought, after the dirt powder sucks pulmonary, make it to have destroyed lung tissue structure, the impairment of the spleen with the passing of time gradually, be impairment of the kidney, though pathological changes is at lung, because of the spleen is the source of growth and development, insufficiency of the spleen then essence of water and grain can not be gone up defeated and lung, lung Tianjin deficiency is difficult autotrophy, makes lung yin day void, yet at present in the Chinese traditional treatment at this mechanism, still find no effect, treat the medicine of pneumoconiosis in a short time, and pulmonary tuberculosis is frequently-occurring disease in recent years, brings very big misery to the patient, and the phthisical Chinese medicine curative effect of existing treatment is long, therapeutic effect is not obvious, very easily causes drug resistance.
Three, summary of the invention:
The object of the present invention is to provide a kind of Chinese medicine and preparation method that is used for the treatment of pneumoconiosis and drug-tolerant pulmonary tuberculosis, it is according to the Dialectic Theory of the traditional Chinese medical science, synergism by all medicines improves and removing pathology residue, make it defeated and lung on the organic substance such as body fluid, thereby reach quick alleviation, remove pathogenic factor, get well.
For achieving the above object, the technical solution used in the present invention is:
A kind of Chinese medicine that is used for the treatment of pneumoconiosis and drug-tolerant pulmonary tuberculosis is characterized in that: raw material composition and the weight proportion thereof of making described Chinese medicine are: Cordyceps 8-12 part, Gecko 3-7 part, Rhizoma Pinelliae 250-350 part, Fructus Lycii 25-300 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 250-300 part, Radix Platycodonis 15-50 part, Cortex Mori 3-20 part, Fructus Schisandrae Chinensis 3-20 part, Radix Glycyrrhizae 250-350 part, Bulbus Fritillariae Uninbracteatae 45-55 part, Semen Armeniacae Amarum 15-25 part, Radix Asteris 15-25 part, Flos Farfarae 25-35 part, Rhizoma Belamcandae 15-25 part, Radix Adenophorae (Radix Glehniae) 8-12 part, Pericarpium Citri Reticulatae 8-12 part, MARONG 8-12 part, Radix Polygalae 10-20 part, tangerine 8-12 part, Semen Ginkgo core 15-25 part, Fructus Trichosanthis shell 15-25 part, Bombyx Batryticatus 15-25 part, Placenta Hominis 8-12 part, Radix Scutellariae 4-8 part, Radix Peucedani 8-12 part, CHAISUZI 8-12 part.
A kind of Chinese medicine that is used for the treatment of pneumoconiosis and drug-tolerant pulmonary tuberculosis is characterized in that: raw material composition and the weight proportion thereof of making described Chinese medicine are: Cordyceps 8-12 part, Gecko 3-7 part, Fructus Lycii 25-300 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 250-300 part, Radix Platycodonis 15-50 part, Cortex Mori 3-20 part, Fructus Schisandrae Chinensis 3-20 part, Radix Glycyrrhizae 250-350 part, Bulbus Fritillariae Uninbracteatae 45-55 part, Radix Salviae Miltiorrhizae 15-45 part, Radix Pseudostellariae 60-80 part, Semen Armeniacae Amarum 15-25 part, Radix Asteris 15-25 part, Flos Farfarae 25-35 part, Rhizoma Belamcandae 15-25 part, Radix Adenophorae (Radix Glehniae) 8-12 part, Pericarpium Citri Reticulatae 8-12 part, MARONG 8-12 part, Radix Polygalae 10-20 part, tangerine 8-12 part, Semen Ginkgo core 15-25 part, Fructus Trichosanthis shell 15-25 part, Bombyx Batryticatus 15-25 part, Placenta Hominis 8-12 part, Radix Scutellariae 4-8 part, Radix Peucedani 8-12 part, CHAISUZI 8-12 part.
A kind of preparation method of Chinese medicine that is used for the treatment of pneumoconiosis and drug-tolerant pulmonary tuberculosis may further comprise the steps:
(1) uses ultraviolet radiation disinfection;
(2) pulverize;
(3) oven dry;
(4) reuse ultraviolet radiation disinfection;
(5) adopt existing pellet processing machine to make pill.
Relative and the prior art of the present invention has the following advantages and effect:
1, can make each visceras function reparation rapidly, lesions position improves, and has broken Chinese medicine to the slow present situation of pneumoconiosis curative effect;
2, except that treatment to pneumoconiosis and pulmonary tuberculosis, also cold various pneumonopathy that cause of lung-heat and cough all there are the rapid healing curative effect, the dizziness insomnia that lassitude loin and legs, deficiency of kidney-QI, yang-energy surplus are caused, dysphoria with feverish sensation in the chest palms and soles night sweat etc. are also effective in cure;
3, pure Chinese medicinal preparation, without any side effects, can contain the state of an illness rapidly, promote vigour, enhancing human body immunity power, in a short time reach healings, be difficult for recurring.
4, broken drug resistance and the Drug resistance of Western medicine, based on nourishing YIN to lower pathogenic fire, had and transfer the gas of enriching blood, the effect of training spleen reinforcing kidney, enrich and benefit essence and blood, strengthening the body resistance pneumoconiosis and pulmonary tuberculosis.Adopt Drug therapy of the present invention can recover lung tissue fully, make the lung tissue calcification and can only reach unlike existing medicine.Symptoms such as the patient can eliminate after taking medicine 20-30 days and become thin, diet reduces, weak, night sweat and asthma.
Four, the specific embodiment:
Embodiment 1 (treatment pneumoconiosis):
Cordyceps 10 grams, Gecko 10 grams, Radix Salviae Miltiorrhizae 30 grams, Radix Pseudostellariae 0-25 part, the Rhizoma Pinelliae 300 grams, Fructus Lycii 300 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 300 grams, Radix Platycodonis 50 grams, Cortex Mori 20 grams, Fructus Schisandrae Chinensis 20 grams, Bulbus Fritillariae Uninbracteatae 50 grams, Radix Glycyrrhizae 300 grams, Semen Armeniacae Amarum 20 grams, Radix Asteris 20 grams, Flos Farfarae 30 grams, Rhizoma Belamcandae 20 grams, Radix Adenophorae (Radix Glehniae) 10 grams, Pericarpium Citri Reticulatae 10 grams, MARONG 10, Radix Polygalae 15 grams, tangerine 10, Semen Ginkgo core 20 grams, Fructus Trichosanthis shell 20 grams, Bombyx Batryticatus 20 grams, Placenta Hominis 10 grams, Radix Scutellariae 6 grams, Radix Peucedani 10 grams, CHAISUZI 10 grams.
Preparation method is an existing conventional pill preparation method: (1) is with the said components ultraviolet radiation disinfection; (2) pulverize; (3) oven dry; (4) reuse ultraviolet radiation disinfection; (5) adopt existing pellet processing machine to make pill.
Embodiment 2 (treatment drug-tolerant pulmonary tuberculosis):
Cordyceps 10 grams, Gecko 10 grams, Radix Salviae Miltiorrhizae 30 grams, Radix Pseudostellariae 70 grams, Fructus Lycii 300 grams, the Pseudobulbus Bletillae (Rhizoma Bletillae) 300 grams, Radix Platycodonis 50 grams, Cortex Mori 20 grams, Fructus Schisandrae Chinensis 20 grams, Bulbus Fritillariae Uninbracteatae 50 grams, Radix Glycyrrhizae 300 grams, Semen Armeniacae Amarum 20 grams, Radix Asteris 20 grams, Flos Farfarae 30 grams, Rhizoma Belamcandae 20 grams, Radix Adenophorae (Radix Glehniae) 10 grams, Pericarpium Citri Reticulatae 10 grams, MARONG 10, Radix Polygalae 15 grams, tangerine 10, Semen Ginkgo core 20 grams, Fructus Trichosanthis shell 20 grams, Bombyx Batryticatus 20 grams, Placenta Hominis 10 grams, Radix Scutellariae 6 grams, Radix Peucedani 10 grams, CHAISUZI 10 grams.
Preparation method is with embodiment 1.
Motherland's medical science thinks that " the lung master breathes; the gas of main the whole body; The spleen has the function to transport and transform nutrients; be the river of QI and blood biochemistry; lung qi a surname fall; the strong fortune of temper, then can transformation of body flaud ", so the relation of lung and spleen, be mainly reflected in the generation of gas and two aspects of conveying of body fluid; the present invention adopts Cordyceps; Gecko; the Rhizoma Pinelliae; Fructus Lycii; the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Platycodonis, Cortex Mori, Fructus Schisandrae Chinensis, tens of flavor Chinese medicines such as Radix Glycyrrhizae are formed, make separately medicine reach its maximum magnitude of performance by mediation, eliminate the cause of disease, the restoration and reconstruction lung, spleen, visceras functions such as kidney, in the side, Gecko has the tonifying the lung Dingchuan, kidney tonifying is supporing yang, the controlling nocturnal emission with astringent drugs nourishing YIN to lower pathogenic fire effect of nourishing blood; The Rhizoma Pinelliae has the drying dampness to eliminate phlegm spleen invigorating, the effect of dissolving lump and resolving mass parasite killing, and have toxicity, and to associate with Radix Glycyrrhizae, it separates toxicity; The Pseudobulbus Bletillae (Rhizoma Bletillae) has tonifying the lung hemostasis, detumescence, granulation promoting, holds back the skin ulcer effect; Radix Platycodonis bitter in the mouth and suffering have the lung qi dispersing evacuation of pus of eliminating the phlegm, and medicine carrying is up, is good at consulting other medicines, treatment human body upper body disease; The Cortex Mori sweet in the mouth is cold in nature, and eliminating pathogen from the lung for relieving asthma is arranged, the inducing diuresis to remove edema effect; The convergence of Fructus Schisandrae Chinensis antitussive, cough-relieving is promoted the production of body fluid; Radix Glycyrrhizae invigorating the spleen and replenishing QI, expelling phlegm for arresting cough, nourishing spleen and stomach, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription, clean the effect of hundred poison, so concentrate Gecko, the five tastes, Fructus Lycii, Rhizoma Pinelliae compatibility Cortex Mori, Radix Platycodonis, Radix Glycyrrhizae nourishing the moon of spleen kidney, negative and positive of qi and blood belongs to and calms down and reach taking-up pathogenic factor, the effect that regains the function.
The present invention is based on modern clinical experience, offer and source investigation, number flavor herbal nature in the prescription is carried out as detailed below in conjunction with long-term clinical practice and preliminary clinical research case with reference to successive dynasties doctor ancient Chinese prose:
1, Cordyceps
Source: be the larva cadaveric complex of the Stroma of Clavicipitaceae plant Cordyceps fungus and host's Hepialidae insecticide Cordyceps Hepialus armorieanus Oberthur thereof etc.
Meridian distribution of property and flavor: sweet, flat; Return lung, kidney channel.
Performance characteristics: have tonifying deficiency, beneficial vital essence, kidney-reinforcing Yang-strengthening, tonifying the lung is relievingd asthma, relieving cough and resolving phlegm effect and the negative dirty function of adjusting kidney.
2, Gecko
Source: the dry body of Gekkonidae animal Gecko Gekko gecko Linnaeus.
Meridian distribution of property and flavor: salty, flat; Return lung, kidney channel.
Performance characteristics: have tonifying the lung gas, benefiting essence-blood, supporing yang road, invigorating the lung and the kidney is breathed heavily in cough-relieving, improving inspiration by invigorating kidney-QI Dingchuan, the smart effect of supporing yang benefit.
3, the Rhizoma Pinelliae
Source: the tuber of the aroid Rhizoma Pinelliae
Nature and flavor: suffering, temperature, poisonous; Go into spleen, stomach warp.
Performance characteristics: be used for the abundant expectoration cough, breast gastral cavity painful abdominal mass is vexed, the thoracic obstruction, blocked-up chest, phlegm resistance.
4, Fructus Lycii
Source: the mature fruit of dicotyledon medicine matrimony vine of solanaceae plant.
Meridian distribution of property and flavor: sweet, flat; Go into liver, stomach two warps, doublely go into lung meridian.
Performance characteristics: have effects such as the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, blood-enriching tranquillizing, promoting the production of body fluid to quench thirst, nourishing the lung to arrest cough, be used for that Liver and kidney is deficient, asthenia of essence and blood, soreness of the waist and knees, dizzy tinnitus, seminal emission, infertile, deficiency of kidney essence, symptoms such as the xerostomia of quenching one's thirst, frequent micturition red tongue.
5, the Pseudobulbus Bletillae (Rhizoma Bletillae)
Source: herbaceos perennial Pseudobulbus Bletillae (Rhizoma Bletillae) rhizome.
Meridian distribution of property and flavor: bitter in the mouth, sweet, puckery, cold in nature; Return lung, stomach, Liver Channel.
Performance characteristics: have astringing to arrest bleeding, the effect of detumescence and promoting granulation; All cards of external haemorrhage and carbuncle, scald, rhagadia manus et pedis, anal fissure etc. in being used for.
6, Radix Platycodonis
Source: exsiccant of campanulaceae Platycodon grandiflouorum.
Meridian distribution of property and flavor: bitter in the mouth, suffering, property are put down; Attach to the lung and stomach meridians.
Performance characteristics: have lung qi dispersing, eliminate the phlegm, the effect of sore-throat relieving, evacuation of pus; Be used for cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache, uroschesis etc.
7, Cortex Mori
Source: the exsiccant skin of mulberry.
Meridian distribution of property and flavor: sweet in the mouth, little hardship; Return lung, spleen channel
Performance characteristics: be used for dyspnea and cough due to lung-heat, distension dyspnea with rapid respiration; Outstanding kind purte the white and relieving asthma and cough, control the lung-heat cough with asthma, the thick and Huang etc. of expectorant.
8, Fructus Schisandrae Chinensis
Source: the fruit of magnoliaceae schisandra (Latin is called FructusSchisandraeChinensis).
Meridian distribution of property and flavor: temperature, acid, sweet; Return lung, the heart, kidney channel.
Performance characteristics: effect with astringent or styptic treatment for spontaneous sweating, the supplementing QI for promoting the production of body fluid of convergence, kidney calming.Be used for that chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound are thirsty, symptoms such as the deficient pulse of losing heart, interior-heat are quenched one's thirst, palpitation and insomnia.
9, Radix Glycyrrhizae
Source: dicotyledon pulse family Leguminosae Radix Glycyrrhizae Glycyrrhiza uralensisFisch., Glycyrrhiza inflata Bat. G.inflata Bat., or the root and rhizome of Glycyrrhiza glabra L. G.glabra L..
Meridian distribution of property and flavor: property is flat, sweet in the mouth; Return 12 warps.
Performance characteristics: have invigorating the spleen and replenishing QI; Heat-clearing and toxic substances removing; Expelling phlegm for arresting cough; Relieving spasm to stop pain; Effects such as coordinating the actions of various ingredients in a prescription are used for the anxious pain of weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, symptom such as strong.
10, Bulbus Fritillariae Uninbracteatae
Source: the underground bulb of Liliaceae herbaceos perennial Bulbus Fritillariae Uninbracteatae.
Meridian distribution of property and flavor hardship, sweet is slightly cold; Return lung, heart channel.
Performance characteristics: effect with clearing heat and moistening lung, preventing phlegm from forming and stopping coughing; Be used for symptoms such as cough due to lung-heat, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood.
11, Radix Salviae Miltiorrhizae
Source: the dry root and rhizome of dicotyledon Labiatae Labiatae Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bge..
Meridian distribution of property and flavor: hardship is slightly cold; GUIXIN, Liver Channel.
Performance characteristics: have effects such as pain relieving, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Be used for that costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen caking, skin infection swell and ache, the tumbling down pain of injury, menoxenia, amenorrhea dysmenorrhea, puerperal symptom such as stasis of blood pain.
12, Radix Pseudostellariae
Source: the tuber of pinkwort pseudostellaria heterophylla Pseudostellaria heterophylla (Miq.) Pax ex Pax et Hoffm..
Meridian distribution of property and flavor: sweet, little hardship, tepor, nontoxic; Go into the heart, spleen, lung three warps.
Performance characteristics: have the effect of mending strengthening spleen and lung, supplementing QI for promoting the production of body fluid; Symptoms such as being used for cough due to deficiency of the lung, insufficiency of the spleen lack of appetite, cardiopalmus, palpitation with a distress feeling, edema, quenching one's thirst, spirit is tired.
13, Semen Armeniacae Amarum
Source: the seed of rosaceous plant Fructus Pruni.
Meridian distribution of property and flavor: sweet in the mouth, property is flat.Lung; Spleen; Large intestine channel
Performance characteristics: have expelling phlegm for arresting cough; Relieving asthma; Intestine moistening; The effect of following air to open numbness is used for cough due to consumptive disease, asthma, and the breast abdomen is contrary vexed; The dryness of the intestine constipation, constipation with dry stool.
14, Radix Asteris
Source: the dry root and rhizome of feverfew Radix Asteris
Meridian distribution of property and flavor: bitter, sweet, tepor.Return lung meridian.
Performance characteristics: have nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm, antibiotic anticancer effect is used for abundant expectoration and breathes with cough, and new chronic cough is coughed the chronic cough hemoptysis.
15, Flos Farfarae
Source: the alabastrum of thymelaeceae plant Edgeworthia chrysantha Lindl..
Nature and flavor: lightly seasoned, property is flat, and is nontoxic.″
Control optic atrohic blindness, cataracta, many tears, photophobia, nocturnal emission, empty pouring, aphonia.
16, Rhizoma Belamcandae
Source: irides Rhizoma Belamcandae rhizome.
Meridian distribution of property and flavor: hardship, cold.Go into lung, Liver Channel.
Performance characteristics: have heat-clearing and toxic substances removing, throat, the effect of expectorant saliva; Be used to experience wind heat, or expectorant heat is stopped up diseases such as laryngopharynx swelling and pain due to containing and accumulation and obstruction of sputum, cough and asthma.
17, Radix Adenophorae (Radix Glehniae)
Source: the root of campanulaceae plant Folium Pruni Radix Adenophorae (Radix Glehniae) Adenophora stricta Miq..
Meridian distribution of property and flavor: bitter, be slightly cold, nontoxic; Attach to the lung and stomach meridians.
Performance characteristics: have nourishing YIN and moistening the lung, the effect of reinforcing stomach reg fluid, the dry cough expectorant that is used for due to lung-dryness syndrome due to deficiency of YIN or the thermal burn lung yin is few, the dry mouth and throat due to dry laryngopharynx and thermal burn stomach-Yin or the Yin and fluid deficiency, the few tongue of red tongue, diseases such as constipation with dry stool.
18, Pericarpium Citri Reticulatae
Source: the dry mature skin of rutaceae orange Citrus reticulata Blanco and variety thereof.
Meridian distribution of property and flavor: bitter, hot, temperature; Return lung, spleen channel.
Performance characteristics: have regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, the effect of diuretic relieving constipation; Be used for incoordination between the spleen and stomach, fullness in the epigastrium and chest, lack of appetite and vomiting, accumulation of phlegm-damp in the lung, cough with copious phlegm, chest and diaphragm is full vexed, symptoms such as the vertigo.
19, Radix Polygalae
Source: the dry root of milk wort Radix Polygalae Polygala tenuifolia Willd. or ovum leaf Radix Polygalae Polygalasibirica L..
Meridian distribution of property and flavor: bitter, hot, tepor; GUIXIN, kidney, lung meridian
Performance characteristics: have the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, the effect of detumescence; Be used for the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, diseases such as breast swell and pain.
20, dried tangerine peel
Source: the dry outer peel of rutaceae Huazhou Fructus Citri tangerinae Citrus grandis Osbeck var.tomentosa Hort. or Fructus Citri tangerinae Citrus reticulata Blanco and variety thereof.
Meridian distribution of property and flavor: hot, bitter, temperature; Return lung, spleen channel.
Performance characteristics: cold expelling, dampness, promoting the circulation of QI, expectorant; Be used for the cough due to wind and cold, the itching of the throat abundant expectoration, food stagnation is got sick from drinking too much wine, the vexed grade of vomiting and nausea painful abdominal mass disease.
21, Semen Ginkgo core
Source: the dry mature seed of Ginkgoaceae plant Ginkgo biloba (maidenhair tree, Gong Sunshu).
Meridian distribution of property and flavor: sweet, bitter, puckery, flat; Poisonous; Return lung meridian.
Performance characteristics: have astringing lung QI for relieving asthma, leukorrhagia stopping is turbid, the effect of urine reducing; Be used for abundant expectoration and breath with cough, leukorrhagia nebulousurine, symptoms such as enuresis frequent micturition.
22, Bombyx Batryticatus
The source: the larva of Bombycidae insecticide bombyx mori infects muscardine and ossified dry Scorpio.
Meridian distribution of property and flavor: salty in the mouth is flat; Go into liver, lung, the stomach warp.
Performance characteristics: have relieving spasm by subduing liver-wind, powder detoxifcation, atmosphere of news service itching relieving effect; Be used for infantile convulsion and twitch, the apoplexy facial hemiparalysis, tetanus, migraine and general headache, tuberculous lymphadenitis, mumps, laryngopharynx swelling and pain, conjunctival congestion is shed tears, toothache ulcerative gingivitis, woman's metrorrhagia and leukorrhagia, furuncle swelling toxin, diseases such as rubella pruritus.
23, Placenta Hominis
Source: people's dry Placenta Hominis.
Meridian distribution of property and flavor: sweet in the mouth, salty, warm; Go into lung, the heart, kidney channel,
Performance characteristics: have the kidney invigorating and essence nourishing, the merit of benefiting QI and nourishing blood; Be used for diseases such as deficient, weakness and emaciation, hemoptysis asthma, consumptive fever hectic fever due to YIN-deficiency, seminal emission.
24, Radix Scutellariae
Source: the dry root of labiate Radix Scutellariae Scutellaria baicalensis Georgi.
Meridian distribution of property and flavor: hardship, cold; Return lung, gallbladder, spleen, large intestine, small intestine meridian.
Performance characteristics: have heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect; Be used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, the cough due to lung-heat, the hyperpyrexia excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, diseases such as frequent fetal movement.
25, Radix Peucedani
Source: the dry root of samphire RADIX PEUCEDANI Peucedanum decursiyum (Miq.) Maxim..
Meridian distribution of property and flavor: be slightly cold bitter in the mouth, suffering; Return lung, spleen channel.
Performance characteristics: have diffusing wind heat clearing away, the effect of lowering the adverse-rising QI to resolve phlegm; Be used for diseases such as cough due to pathogenic wind-heat's abundant expectoration, the expectorant dyspnea of heat type is full, the Huang of coughing up phlegm is thick.
The present invention is based on the clinical dialectical theory of the traditional Chinese medical science, adopt building up the spleen to supplement the lung, the mechanism of strengthening the body resistance is adjusted and taste, makes it to digest and assimilate the elite of grain rice, and nutrition is in each internal organs, makes it to fail in lung on the organic substance such as body fluid, makes lung Tianjin burn phenomenon and progressively improves.
The present invention treats the effect of drug tolerance pulmonary tuberculosis Chinese medicine to infecting mouse:
Select 45 of mices, inject the HR37V reference culture for every mouse vein, be mixed with 5mg/ml with normal saline, every is injected 0.2ml.Infect and played gastric infusion in preceding 5 days, continue administration 5 days after the microbiological contamination, dosage sees Table 1.Every treated animal death toll in 20 days is calculated mortality rate after the observation microbiological contamination.Dead mice and survival mice lungs are taken out, give the score of lung lesion degree, ask the lung index, judge drug effect, the results are shown in Table 1 and table 2 according to score with the YOUMANShi method.Medicine of the present invention as seen from Table 1 can obviously prolong the mice time-to-live, reduces mortality rate, to infecting the tuberculosis mice obvious protective effect is arranged.Medicine 4g/kg dosage of the present invention as seen from Table 2 can obviously suppress pneumonopathy range degree, and the lung index is 0.58, shows tuberculosis treatment effective.
Table 1 the present invention treats drug tolerance pulmonary tuberculosis Chinese medicine to the effect of infecting mouse (X ± S)
*P＜0.05 **P＜0.01
Table 2 medicine of the present invention is to the influence of mouse lung disease of ZANG-organs range degree (X ± S)
* the lung exponential quantity is effective between 0.5-0.7.
The effect experiment of treatment by Chinese herbs pneumoconiosis of the present invention:
Select 80 patients as observing treatment target, be divided into two groups at random, wherein 40 examples are organized in treatment, matched group 40 examples, the treatment group is taken the pill of treatment pneumoconiosis of the present invention, instructions about how to take medicine: every ball contains patent medicine 12 grams, take two balls every day, eliminating cold for resuscitation water send down, and period in a medicine is avoided clothes rareripe, living Bulbus Allii, tobacco and wine.Be a course of treatment January.Matched group is treated with Asmeton"strong" Capsules (Japan rises field pharmacy commercial firm and makes), and dose is taken as requested.The equal had palpitation of selected patient, uncomfortable in chest, breathe hard, the symptom of easy to catch cold and complicated with pulmonary infection.The pneumoconiosis diagnosis is pressed the pneumoconiosis X line of national regulation and is carried out with diagnostic criteria by stages, and X line rabat can reflect the pathological change of pneumoconiosis, and the clinical symptoms comparative result sees Table 3 between two groups.
Table 3 liang group pneumoconiosis X radiodiagnosis x typing relatively
| Group | The example number | The I phase | The II phase | The III phase |
| The treatment group | 40 | 30 | 8 | 2 |
| Matched group | 40 | 32 | 7 | 1 |
Criterion of therapeutical effect: 1, produce effects: clinical symptom disappearance, not catch a cold more than two months, X line rabat pathological changes does not have development; 2, effective: clinical symptom relief, do not catch a cold the suspicious person of X line rabat pathological changes within one month; 3, invalid: the clinical symptoms no change, X line rabat has development person.Therapeutic outcome sees Table 4 and table 5.As can be seen from Table 4, two groups of patients' flu incidence rate treatment group is starkly lower than matched group, exists significant difference between two groups of cases.As can be seen from Table 5, the treatment group significantly is better than matched group on curative effect, proves that Chinese medicine of the present invention has definite therapeutic effect to pneumoconiosis.
Table 4 liang group flu incidence rate relatively
P＜0.01
Table 5 liang group clinical efficacy relatively
| Group | The example number | Produce effects | Effectively | Invalid | Total effective rate |
| The treatment group | 40 | 20 | 17 | 3 | 92.5％ |
| Matched group | 40 | 0 | 9 | 31 | 22.5％ |
P＜0.01
Medicine pill treatment case of the present invention is listed below:
Case 1:
Patient: Zhang Zhonghong, man, 44 years old, the 3 groups of people in various schools of thinkers village, town, loess mountain range, Dashiqiao City, Liaoning Province;
The cause of disease: coal mine working for many years, when going home rest, the self-induction general fatigue is unable unintentionally, cough, breathe hard, be diagnosed as viral influenza in local clinic, after a weeks treatment, the invalid commentaries on classics in bridge Shi Shi the People's Hospital, be diagnosed as the concurrent tuberculosis of pneumosilicosis on inspection, through the treatment, symptom makes moderate progress, but because of economic cause go home the mastery, during the mastery, walk two and go on foot the rest of just need squatting down, asthma, cough, fever in the afternoon, general weakness, chest pain, poor appetite, become thin, getting up early has nauseating, the symptom of vomiting, yellow sputum, idol is told yellow fluid, big dry stool, no labour force, after the warp of being in hospital again
Have a medical check-up: stringy pulse, count accurately, tongue is white, red tip of the tongue, Shao Jin;
The X radiodiagnosis x is: sick 3 grades of the concurrent cavernous pulmonary tuberculosis of pneumosilicosis;
Instructions about how to take medicine: every ball contains patent medicine 12 grams, takes two balls every day, and eliminating cold for resuscitation water send down, and period in a medicine is avoided clothes rareripe, living Bulbus Allii, tobacco and wine.
The treatment degree: take this medicine pill after 15 days, cough, asthma begin to alleviate, early the nauseating transference cure of time-out, after 20 days, the patient can slowly walk, and fever in the afternoon alleviates, the chest pain number of times reduces, after 30 days, patient's face has ruddy, and diet increases, stool is normal, after 90 days, the patient can activity freely, competent slight muscular labor.
Case 2:
Li Jingfu, man, 35 years old, the 5 groups of people in Xia Xianyu village, town, loess mountain range, Dashiqiao City, Liaoning Province, coal miner;
The cause of disease: checked before 3 years that the patient suffers from pneumoconiosis, the X line is 3 grades of pneumosilicosis, patient's cough, expectoration, uncomfortable in chest, chest pain, have palpitation, breathe hard, become thin, weak all over, can't take care of oneself, be afraid of cold, night sweat, hectic fever in the afternoon have repeatedly hemoptysis phenomenon, warp
Have a medical check-up: stringy pulse, white, the few Tianjin of tongue fur;
The X line: epimere all has big or small irregular shade and tuberosity in two lungs;
Instructions about how to take medicine: every ball contains patent medicine 12 grams, takes two balls every day, and eliminating cold for resuscitation water send down, and period in a medicine is avoided clothes rareripe, living Bulbus Allii, tobacco and wine.
Treatment degree: on May 12nd, 2007 began to take this medicine pill, patient's cough, expectoration, chest pain begin to alleviate after 20 days, nervous breathing hard make moderate progress, patient's walking that begins to leave the bed after 30 days, and the patient can do slight muscular labor after 90 days, but because of economic cause, drug withdrawal.
Case 3:
Shen Yuhua: man, 36 years old, phoenix people from town, Zuoshui County, Shaanxi Province;
The cause of disease: patient's beginning in 24 years old Shanxi coal mine working, checked the easily loyal pneumoconiosis that goes up before 4 years, the beginning non-evident sympton, just do not take notice of that the planting vegetable of being in is when idol and Changes in weather, just begin cough, expectoration, uncomfortable in chest, breathe hard, local clinic is with common cold treatment (antiinflammatory is controlled and coughed medicine), also take a turn for the better to some extent, slowly above-mentioned symptom begins to increase the weight of, begin to become thin, night sweat, loss of appetite, tired general unable, chest pain, slowly walking all feel breathe hard, local doctor advises going the inspection of province tuberculosis hospital;
CT confirms as: stage merges pulmonary tuberculosis, hospitalization, and symptom makes moderate progress after three months, and because of expense is too high, the patient requires the recuperation of going home, after have a medical check-up:
Arteries and veins picture: count accurately, string, red tip of the tongue, Shao Jin;
Instructions about how to take medicine: every ball contains patent medicine 12 grams, takes two balls every day, and eliminating cold for resuscitation water send down, and period in a medicine is avoided clothes rareripe, living Bulbus Allii, tobacco and wine.
The treatment degree: take traditional Chinese medicine pill after 15 days, cough, expectoration alleviate, and appetite increases, and the chest pain number of times reduces, and after one month, breathing hard alleviates, and have rosy cheeks, and after six months, patient's self-induction symptomatology disappears, and can do physical labor.
Case 4:
Wang Zhizhong: man, 28 years old, the Sanmenxia City people of Henan Province;
The cause of disease: in the time of 23 years old, follow the elder brother and beat drilled dry in certain ore deposit; In the time of 25 years old, often occur that cough is breathed hard, power uncomfortable in chest, general, night sweat symptom, at local examination in hospital x line justification: stage, tuberosity is greater than 2cm, left hospital in two months in local hospitalize, symptom makes moderate progress, but still yellowish complexion, thin, walk slowly, play is coughed, a large amount of yellow sputum, breathe hard, uncomfortable in chest; After have a medical check-up: thready and stringy pulse, white, the few Tianjin of tongue fur;
Instructions about how to take medicine: every ball contains patent medicine 12 grams, takes two balls every day, and eliminating cold for resuscitation water send down, and period in a medicine is avoided clothes rareripe, living Bulbus Allii, tobacco and wine.
The treatment degree: behind the pill one month of taking traditional Chinese medicine, all symptoms begin to take a turn for the better, and after six months, the x sheet sees that two lung yin shadows are thin out, and tuberosity is less than 1cm, continues medication, rehabilitation after 12 months.
Case 5:
Duan Pingan, man, 68 years old, the Hanzhong City people of Shaanxi Province;
The cause of disease: two more than ten years of hectic, and with rheumatic heart disease, when coming to daughter home to act as a guest, the state of an illness increases the weight of, the back is week poor effect of high-new hospitalize in the Xian City, Shanxi Province, still have cough, chest pain, cough pink foam sample disease, fever in the afternoon, Sleep hyperhidrosis, white, the rolling pulse of house
Instructions about how to take medicine: every ball contains patent medicine 12 grams, takes two balls every day, and eliminating cold for resuscitation water send down, and period in a medicine is avoided clothes rareripe, living Bulbus Allii, tobacco and wine.
The treatment degree: take this medicine pill after 30 days, cough alleviates, and expectorant is white, foam sample, after 60 days, and to examination in hospital, the dark cloudy calcification fully of pulmonary tuberculosis, the rheumatic heart disease page or leaf takes a turn for the better to some extent.
Case 6:
Open X silver, woman, 32 years old, people from Lantian County, Shaanxi Province;
The cause of disease: in March, 2004 because of heating, cough, expectoration, after failing to respond to any medical treatment in the locality, change county hospital over to, 38 ° of body temperature, it is more and more heavier to cough, having a blood test heavy is 100, X-ray sees that there is lamellar shade in various degree in two pulmonarys, is diagnosed as pulmonary tuberculosis, changes city tuberculosis hospital over to, while in hospital, body temperature is reduced to 37.2 °, and cough, expectoration alleviate to some extent, but the patient is heavy unable night, extremity are aching and limp to be increased the weight of, after leave hospital;
Instructions about how to take medicine: every ball contains patent medicine 12 grams, takes two balls every day, and eliminating cold for resuscitation water send down, and period in a medicine is avoided clothes rareripe, living Bulbus Allii, tobacco and wine.
The treatment degree: take our medicine pill after 30 days, cough, expectoration transference cure, complexion begins ruddy, and after 60 days, above transference cure, X-ray see that two pulmonary shadows are all with calcification.
Clinical data shows that the effect of medicine pill of the present invention is conspicuous:
1. cure rate is up to 91.7%, total effective rate 97.7%.
2. follow up a case by regular visits to after more and show, do not recur after more.
3. the patient is followed up a case by regular visits to and show that this medicine pill has no side effect, no Drug resistance and drug resistance.
4. to the patient of all ages and classes, dissimilar pneumoconiosis all has produce effects.
Claims (3)
1, a kind of Chinese medicine that is used for the treatment of pneumoconiosis and drug-tolerant pulmonary tuberculosis is characterized in that: raw material composition and the weight proportion thereof of making described Chinese medicine are: Cordyceps 8-12 part, Gecko 3-7 part, Rhizoma Pinelliae 250-350 part, Fructus Lycii 25-300 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 250-300 part, Radix Platycodonis 15-50 part, Cortex Mori 3-20 part, Fructus Schisandrae Chinensis 3-20 part, Radix Glycyrrhizae 250-350 part, Bulbus Fritillariae Uninbracteatae 45-55 part, Semen Armeniacae Amarum 15-25 part, Radix Asteris 15-25 part, Flos Farfarae 25-35 part, Rhizoma Belamcandae 15-25 part, Radix Adenophorae (Radix Glehniae) 8-12 part, Pericarpium Citri Reticulatae 8-12 part, MARONG 8-12 part, Radix Polygalae 10-20 part, tangerine 8-12 part, Semen Ginkgo core 15-25 part, Fructus Trichosanthis shell 15-25 part, Bombyx Batryticatus 15-25 part, Placenta Hominis 8-12 part, Radix Scutellariae 4-8 part, Radix Peucedani 8-12 part, CHAISUZI 8-12 part.
2, a kind of Chinese medicine that is used for the treatment of pneumoconiosis and drug-tolerant pulmonary tuberculosis according to claim 1 is characterized in that: raw material composition and the weight proportion thereof of making described Chinese medicine are: Cordyceps 8-12 part, Gecko 3-7 part, Fructus Lycii 25-300 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 250-300 part, Radix Platycodonis 15-50 part, Cortex Mori 3-20 part, Fructus Schisandrae Chinensis 3-20 part, Radix Glycyrrhizae 250-350 part, Bulbus Fritillariae Uninbracteatae 45-55 part, Radix Salviae Miltiorrhizae 15-45 part, Radix Pseudostellariae 60-80 part, Semen Armeniacae Amarum 15-25 part, Radix Asteris 15-25 part, Flos Farfarae 25-35 part, Rhizoma Belamcandae 15-25 part, Radix Adenophorae (Radix Glehniae) 8-12 part, Pericarpium Citri Reticulatae 8-12 part, MARONG 8-12 part, Radix Polygalae 10-20 part, tangerine 8-12 part, Semen Ginkgo core 15-25 part, Fructus Trichosanthis shell 15-25 part, Bombyx Batryticatus 15-25 part, Placenta Hominis 8-12 part, Radix Scutellariae 4-8 part, Radix Peucedani 8-12 part, CHAISUZI 8-12 part.
3, a kind of preparation method of Chinese medicine that is used for the treatment of pneumoconiosis and drug-tolerant pulmonary tuberculosis as claimed in claim 1 or 2 may further comprise the steps:
(1) uses ultraviolet radiation disinfection;
(2) pulverize;
(3) oven dry;
(4) reuse ultraviolet radiation disinfection;
(5) adopt existing pellet processing machine to make pill.
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| CN102058779A (en) * | 2010-12-24 | 2011-05-18 | 李坤 | Traditional Chinese medicine decoction for treating asthma |
| CN101829276B (en) * | 2010-02-06 | 2011-09-14 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine combination for treating pneumonoconiosis and preparation method thereof |
| CN102357186A (en) * | 2011-11-01 | 2012-02-22 | 北京师范大学 | Chinese medicinal composition for treating pneumoconiosis |
| CN103385980A (en) * | 2013-07-19 | 2013-11-13 | 苏州市天灵中药饮片有限公司 | Decoction for treating pneumonia |
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| CN104189457A (en) * | 2014-09-19 | 2014-12-10 | 袁宗伦 | Traditional Chinese medicine composition for treating pneumoconiosis |
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| CN103638412B (en) * | 2013-12-16 | 2016-04-27 | 王文兮 | Multiple-effect Chinese medicinal formulae of a kind of quick elimination pulmonary persistent ailment and preparation method thereof |
| CN104189457A (en) * | 2014-09-19 | 2014-12-10 | 袁宗伦 | Traditional Chinese medicine composition for treating pneumoconiosis |
| CN105168880A (en) * | 2015-10-08 | 2015-12-23 | 孟令霞 | Compound pharmaceutic preparation for treating pneumoconiosis |
| CN112057580A (en) * | 2020-07-31 | 2020-12-11 | 河南中医药大学 | A traditional Chinese medicine prescription for treating pneumoconiosis with yin deficiency, dryness and heat syndrome and its application |
| CN112057580B (en) * | 2020-07-31 | 2024-04-05 | 河南中医药大学 | Traditional Chinese medicine prescription for treating yin deficiency and dryness heat syndrome of pneumoconiosis and application thereof |
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