CN101496772B - Anti-aging allergy-releasing composition containing plant effective ingredient - Google Patents
Anti-aging allergy-releasing composition containing plant effective ingredient Download PDFInfo
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- CN101496772B CN101496772B CN 200810033341 CN200810033341A CN101496772B CN 101496772 B CN101496772 B CN 101496772B CN 200810033341 CN200810033341 CN 200810033341 CN 200810033341 A CN200810033341 A CN 200810033341A CN 101496772 B CN101496772 B CN 101496772B
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Abstract
The invention provides an anti-aging allergy-relieving composition. The composition comprises effective anti-aging and allergy-relieving ingredients prepared by compatibility of plant extract natural alpha-bisaboll and procyanidins, make-up, skin-care products or pharmaceutically accepted carriers. When the composition is applied to skin, anti-aging and anti-allergy effect superior to independently used natural alphs-bisaboll or procyanidins can be generated.
Description
Technical field
The present invention relates to a kind of anti-aging allergy-releasing composition that contains effective ingredients in plant, relate in particular to a kind of contain effective ingredients in plant be used for skin anti-aging, antianaphylactic cosmetics, skin care item or pharmaceutical preparation.
Technical background
Although skin aging is the natural physiological phenomenon of human body, environmental factors can be aggravated this phenomenon, and female skin is especially true.If in cosmetics, skin care item, add some anti-ageing materials that have no side effect, aging that can delaying skin.
In addition, skin allergy is that common dermatosis, especially cosmetic allergic contact dermatitis are the problems that many women and special occupation person run into, and comprising: lipstick causes reddened and swollen lips, pain, scalp erythema, vesicle that hair dye causes, the pruritus that sunscreen cream, anti-freckle agent cause, pain and pigmentation.Irritated crowd's skin sensitivity is smeared and is seemed simple cosmetics and also untoward reaction can occur.Common are lipstick, hair dye etc., namely occur after the use skin red, swollen, hot, itch, bitterly, the anaphylaxis problem such as get blister, not only can not find beautiful sensation, embarrassment but occurs often.Suppressing and the opposing skin allergy, all is very important problem from skin physiology and medical science and the angle of improving looks.The method treatment of at present traditional control, such as hormones, antihistaminic, although the anti-inflammatory type Drug therapy can make the problem of skin allergy and symptom be eased within the regular hour and treat, if but improper use, probably increase the weight of the state of an illness of skin, even can cause the irremediable pathological changes of skin.Therefore be very worth research for how suppressing safely and effectively the skin allergy problem.
Therefore an object of the present invention is to provide a kind of compositions of new medical science, beauty treatment and used for cosmetic, the compositions of this medical science, beauty treatment and used for cosmetic contains any hormone anything but, and contained active substance all is the extract of the effective ingredients in plant of pure natural.This complex can be blocked anaphylactoid generation from cellular level.The effective ingredient of natural plants, it is non-stimulated to be perfectly safe, thereby has avoided stimulation and the sensitization of chemicals to skin.
Studies show that, in many natural plant extracts, have effective defying age, antianaphylactic material, can utilize it to make cosmetics, skin care item or the medicine with defying age or anti-allergic effects.Natural plants or its extract comprise: Radix Hamamelidis Mollis, Proflavanol, the blue berry extract, Semen Ginkgo extrac, camomile extract, the Fructus Crataegi extract, Radix Glycyrrhizae extract liquid and glycyrrhizic acid, Aloe gel, azulene, Bisabolol, the neutral red bisabolol, Radix Astragali extract, the Flos Lonicerae extract, Flos Chrysanthemi Indici extract, the Radix Isatidis elite, Cordyceps, the Fructus actinidiae chinensis essence, the Fructus Rosae Normalis extract, the Calendula arvensis L. extract, yellow spring flower extract, the Garden lavender essence, the Sargassum essence, Radix Ophiopogonis, Semen Coicis, the jasmine grass, favus skin, the Ganoderma elite, green tea extract, Poria, Radix Scutellariae etc.But single active ingredient often is difficult to the effect that reaches desirable.
Summary of the invention
The object of the present invention is to provide a kind of anti-aging allergy-releasing composition that contains the composite plant effective component extracting, as cosmetics, skin care item or drug use, can play good skin anti-aging and anti-allergic effects.
According to compositions of the present invention, it comprises, the natural α-bisabolol of plant extract and plant extract grasp seed procyanidins, and comprise cosmetics, skin care item or medicine acceptable carrier.
In an embodiment of the present invention, the weight ratio of natural α-bisabolol and grasp seed procyanidins is 1: 5～7: 1 in the described compositions, and both sums account for 0.1～10 % by weight of described compositions.
In the present invention's one preferred implementation, the weight ratio of natural α-bisabolol and grasp seed procyanidins is 1: 1～5: 1 in the described compositions, and both sums account for 1～5 % by weight of described compositions.
In a preferred embodiment of this invention, the present composition also comprises at least a in the following plant extract: Fructus Vitis viniferae oligosaccharide, tea polyphenols, azulene and Rhizoma pinelliae cordatae.
Compositions of the present invention can be cream cream, Emulsion or Gel mile agent, comprises water and oil phase, and water accounts for 92～75 % by weight of described compositions, and wherein said plant extract is contained in described aqueous phase.The active substance that the present composition is contained all is the extract of the effective ingredients in plant of pure natural.When it was applied to skin, the combination of effective ingredient can be blocked anaphylactoid generation from cellular level, plays simultaneously the effect of delay skin aging.And the effective ingredient of natural plants, safe and non-stimulating, thus avoided stimulation and the sensitization of chemicals to skin.
Below with reference to the specific embodiment and embodiment, the technique effect of design of the present invention and generation is described further, to understand fully the present invention.
The specific embodiment
Proposition of the present invention is based on, and we find that in test some plant extract effective ingredient with anti-aging allergy-releasing effect can improve result of use significantly when being used in combination.
Take the cream cream as example, the preparation method of anti-aging allergy-releasing composition is described
Water: natural α-bisabolol and grasp seed procyanidins is water-soluble respectively, then mixing, become water, the weight ratio 1: 5～7: 1 of natural α-bisabolol and grasp seed procyanidins wherein, be to be preferably 10: 4 in 1: 1～5: 1 preferably, and both sums are 0.02～8 % by weight at the content of aqueous phase, are preferably 4.5 % by weight;
Oil phase: oil can be the oil in mineral oil, vegetable oil or other source;
With water and the oil phase weight ratio with 92: 8～75: 25, preferably with 78: 22 part by weight mix, homogenizing, become the cream cream.
Also can add at least a in the following plant extract at aqueous phase: Fructus Vitis viniferae oligosaccharide, tea polyphenols, azulene and Rhizoma pinelliae cordatae.The weight ratio of the natural α-bisabolol of aqueous phase and Fructus Vitis viniferae oligosaccharide can be 10: 1～10: 2, is preferably 10: 1.5.The weight ratio of the described natural α-bisabolol of aqueous phase and tea polyphenols can be 10: 0.6～10: 1.2, is preferably 10: 0.8.The weight ratio of the described natural α-bisabolol of aqueous phase and azulene can be 10: 0.5～10: 2, is preferably 10: 1.The weight ratio of the described natural α-bisabolol of aqueous phase and Rhizoma pinelliae cordatae can be 10: 0.02～10: 0.1, is preferably 10: 0.06.
Embodiment
Raw material:
| Producer | Trade name | Goods number | Specification | |
| Natural α-bisabolol | The sharp chemicals company limited of containing in Shanghai | Natural α-bisabolol | 2/012685 | |
| Grasp seed procyanidins | The sharp chemicals company limited of containing in Shanghai | Semen Vitis viniferae extract | 2/031999 | |
| Ligoglucoside | Dalian Chemistry and Physics Institute natural product and sugared engineering group | No. 3, middle section (ligoglucoside) | ||
| Tea polyphenols | Bold and unconstrained Fine Chemical Co., Ltd is gathered in Shanghai | Tea polyphenols | 99％ | |
| Azulene | Permanent scientific ﹠ trading Co., Ltd. of a specified duration of Beijing Cigna | The Flos Matricariae chamomillae extract | 10％ | |
| Rhizoma pinelliae cordatae | The huge nation in Shifang City plant material company limited | Rhizoma Pinelliae extract | Pro20061124163839 |
Embodiment 1～35 is anti-aging allergy-releasing composition according to the present invention, be specially the cream cream by above-mentioned preparation method preparation, wherein, the weight ratio of water and oil phase is 78: 22, natural α-bisabolol and grasp seed procyanidins sum account for 4.5 % by weight of water, namely account for about 3.5 % by weight of cream cream, oil phase is isopropyl palmitate.
Natural α-bisabolol and grasp seed procyanidins, and and the proportioning of other effective ingredients in plant see Table 1～table 7.
Natural α-bisabolol and the grasp seed procyanidins proportioning of the compositions anti-aging allergy-releasing effective ingredients in plant of embodiment 1～embodiment 16 that table 1～table 3 shows, and result of use.
Table 1
| Embodiment | 1 | 2 | 3 | 4 | 5 |
| Natural α-bisabolol: grasp seed procyanidins | 1∶5 | 1∶4 | 1∶3 | 1∶2 | 1∶1 |
| Effect | Generally | Generally | Generally | Generally | Generally |
Table 2
| Embodiment | 6 | 7 | 8 | 9 | 10 | 11 |
| Natural α-bisabolol: grasp seed procyanidins | 2∶1 | 3∶1 | 4∶1 | 5∶1 | 6∶1 | 7∶1 |
| Effect | Generally | Better | Good | Good | Generally | Generally |
Can find out from the result of embodiment 1～embodiment 11, raising along with natural α-bisabolol concentration, the effect of compositions has improved, if but natural α-bisabolol ground excessive concentration, the antiallergic sense of component can reduce again, this shows that natural α-bisabolol plays than major effect.
On the basis of embodiment 1～embodiment 11, further optimize natural α-bisabolol: the proportioning of grasp seed procyanidins, see table 3 for details.
Table 3
| Embodiment | 12 | 13 | 14 | 15 | 16 |
| Natural α-bisabolol: grasp seed procyanidins | 3∶2 | 4∶3 | 5∶2 | 5∶3 | 5∶4 |
| Effect | Good | Good | Very good | Fine | Better |
Find out that from embodiment 12～17 when natural α-bisabolol: grasp seed procyanidins is 5: 2 best results.
Also added other auxiliary effective ingredients in plant in the compositions of embodiment 17～embodiment 35 shown in table 4～table 7.Wherein, in the compositions of embodiment 17～embodiment 35, natural α-bisabolol: grasp seed procyanidins is fixed as 5: 2.
Table 4
| Embodiment | 17 | 18 | 19 | 20 |
| Natural α-bisabolol: Fructus Vitis viniferae oligosaccharide | 5∶0.25 | 5∶0.5 | 5∶0.75 | 5∶1 |
| Effect | Generally | Good | Fine | Generally |
According to the above results, the natural α-bisabolol of optimization: grasp seed procyanidins: Fructus Vitis viniferae oligosaccharide proportioning is 5: 2: 0.75.
Table 5
| Embodiment | 21 | 22 | 23 | 24 | 25 | 26 |
| Natural α-bisabolol: tea polyphenols | 5∶0.1 | 5∶0.2 | 5∶0.3 | 5∶0.4 | 5∶0.5 | 5∶0.6 |
| Effect | Generally | Generally | Good | Fine | Good | Generally |
According to the above results, the natural α-bisabolol of optimization: grasp seed procyanidins: the tea polyphenols proportioning is 5: 2: 0.4.
Table 6
| Embodiment | 27 | 28 | 29 | 30 |
| Natural α-bisabolol: azulene | 5∶0.25 | 5∶0.5 | 5∶0.75 | 5∶1 |
| Effect | Generally | Fine | Good | Generally |
According to the above results, the natural α-bisabolol of optimization: grasp seed procyanidins: the azulene proportioning is 5: 2: 0.5.
Table 7
| Embodiment | 31 | 32 | 33 | 34 | 35 |
| Natural α-bisabolol: Rhizoma pinelliae cordatae | 5∶0.1 | 5∶0.2 | 5∶0.3 | 5∶0.4 | 5∶0.5 |
| Effect | Generally | Good | Fine | Good | Generally |
According to the above results, the natural α-bisabolol of optimization: grasp seed procyanidins: Rhizoma pinelliae cordatae is 5: 2: 0.03.
Find by a large amount of skin application tests, utilize the combination of the effective ingredients in plant such as above-mentioned natural α-bisabolol and grasp seed procyanidins, the anti-aging allergy-releasing composition of the present invention that obtains with the cosmetics of routine, skin care item or medicine preparation production method, its skin anti-aging, antiallergic effect are much better than the effect of the above-mentioned natural plant composition of independent use.Particularly, compositions in table 1～table 7 is broken into sample, east, the whole nation, south, west, each area, north select respectively the crowd of skin allergy symptom to carry out skin application test, the result shows, the irritated effective percentage of compositions control of embodiment 1～embodiment 11 reaches more than 45%, adopts the embodiment 14,19,24 of effective ingredients in plant optimization proportioning, 28 and 33 the irritated effective percentage of compositions control to reach more than 85%.
By those of ordinary skill is scrutable in the art, described in this description is a kind of preferred embodiments of the present invention, and all changes of making under this invention's idea or modification all should be in claim protection domains of the present invention.
Claims (4)
1. anti-aging allergy-releasing composition, contain the natural ɑ-bisabolol of plant extract and grasp seed procyanidins, and cosmetics, skin care item or medicine acceptable carrier, it is characterized in that: said composition is the cream cream, the weight ratio of water and oil phase is 78:22, and described natural ɑ-bisabolol and described grasp seed procyanidins sum account for 4.5 % by weight of water, namely accounts for about 3.5 % by weight of cream cream, oil phase is isopropyl palmitate, described natural ɑ-bisabolol: the weight ratio of described grasp seed procyanidins is 5:2.
2. compositions according to claim 1 is characterized in that, described compositions also comprises the Fructus Vitis viniferae oligosaccharide, described natural ɑ-bisabolol: described grasp seed procyanidins: the weight ratio of described Fructus Vitis viniferae oligosaccharide is 5:2:0.75.
3. compositions according to claim 1 is characterized in that, described compositions also comprises tea polyphenols, described natural ɑ-bisabolol: described grasp seed procyanidins: the weight ratio of described tea polyphenols is 5:2:0.4.
4. compositions according to claim 1 is characterized in that, described compositions also comprises azulene, described natural ɑ-bisabolol: described grasp seed procyanidins: the weight ratio of described azulene is 5:2:0.5.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102429826B (en) * | 2010-09-29 | 2013-09-25 | 科丝美诗(中国)化妆品有限公司 | Composition of impressive emulsified cosmetics and producing method thereof |
| CN102727415B (en) * | 2012-06-18 | 2013-07-24 | 曾技 | Anti-allergic cosmetic and production process thereof |
| CN103462041B (en) * | 2013-08-06 | 2014-12-17 | 浙江省农业科学院 | Antiallergic citrus dietary fiber preparation method and product thereof |
| CN103479562A (en) * | 2013-09-12 | 2014-01-01 | 严晓燕 | Gingko green tea moisture keeping emulsion |
| CN104706556A (en) * | 2015-03-31 | 2015-06-17 | 苏州维泰生物技术有限公司 | Antiallergic composition and application thereof in cosmetics |
| CN104721098B (en) * | 2015-04-17 | 2015-12-30 | 广州市科玮生物技术有限公司 | A kind of skin Shu Min liquid and its preparation method and application |
| CN105342973A (en) * | 2015-12-11 | 2016-02-24 | 饶雅琴 | Tea polyphenol sun cream and preparation method thereof |
| CN106726965B (en) * | 2016-12-26 | 2020-06-23 | 湖南御家化妆品制造有限公司 | Anti-allergy and soothing skin care product composition and preparation method thereof |
| CN111840118A (en) * | 2020-08-26 | 2020-10-30 | 惠州市蕙薏美生物科技有限公司 | Skin care preparation with hormone repairing face |
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| CN1646151A (en) * | 2002-04-09 | 2005-07-27 | 辛克莱药物有限公司 | Topical pharmaceutical compositions comprising proanthocyanidins for the treatment of dermatitis |
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| CN1646151A (en) * | 2002-04-09 | 2005-07-27 | 辛克莱药物有限公司 | Topical pharmaceutical compositions comprising proanthocyanidins for the treatment of dermatitis |
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Effective date of registration: 20180514 Address after: 201203 Pudong New Area, Shanghai, China (Shanghai) free trade trial area, 351 671-03, Hai Tai Road, Guo Shou Jing Road. Patentee after: Shanghai Lanace Biotechnology Co., Ltd. Address before: 200062 1703, room 15, 3751 lane, Zhongshan North Road, Putuo District, Shanghai. Patentee before: Jiang Ning |
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