CN101444331B - Ultrahigh-pressure extraction method of honeysuckle flower, wild chrysanthemum and mulberry leaf and application of extract liquid thereof - Google Patents
Ultrahigh-pressure extraction method of honeysuckle flower, wild chrysanthemum and mulberry leaf and application of extract liquid thereof Download PDFInfo
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Abstract
The invention discloses an ultrahigh-pressure extraction method of honeysuckle flower, wild chrysanthemum and mulberry leaf and the application of an extract thereof, belonging to the technical field of cigarettes. The ultrahigh-pressure extraction method is to arrange the honeysuckle flower, the wild chrysanthemum and the mulberry leaf in an ultrahigh-pressure extraction tank after the mixing and add 5 times the weight of 60 percent-95 percent ethanol; the pressure of the mixture is increased to 100MPa-400MPa, kept for 8 min and then released immediately; then the mixture is filtrated, after being concentrated to 20 percent-30 percent of the original volume, and the filtrate is refrigerated overnight; the concentrate is separated by a centrifuge for 15 min at the speed of 5000 turns per minute; the concentrate is further filtrated, and the obtained filtrate is the mixed extract liquid of the honeysuckle flower, the wild chrysanthemum and the mulberry leaf. 1 percent-5 percent of the extract liquid is added in cigarette paper pulp by or 0.1 per mill-1 percent of the extract liquid is added in tobacco shred. The method has the advantages of simplicity, practicality, convenient operation, time conservation, low cost, and high yield of extracted effective ingredients. In the invention, the cigarettes prepared by the extract liquid have various health care functions.
Description
Technical field
The invention belongs to technical field of cigarettes, relate to the extraction and the application of extract in cigarette thereof of honeysuckle, mother chrysanthemum, three kinds of mixture of Chinese herbal medicines of mulberry leaf.
Background technology
Great mass of data shows, in smoking process, some harmful substances in the flue gas can be to human body throat, nasal cavity produces stimulates, it is residual that lingual surface is had, thereby allows the people produce unjoyful sense, and is detrimental to health.Thereby the researcher of tobacco business is adjusting the cigarette prescription always, reduces the harm of cigarette to human body as far as possible.A kind of method commonly used is with being of value to health in the Chinese herbal medicine and can reducing that the composition of harmful substance joins in the cigarette in the tobacco, to weaken the harm of tobacco to human body.Honeysuckle, mother chrysanthemum, mulberry leaf all are traditional Chinese medicines, and property is sweet, be slightly cold, and return lung, Liver Channel.Be used for clearing heat and detoxicating, clear throat, promoting production of body fluid and nourishing the lung, and mother chrysanthemum also has the effect of its uniqueness aspect fresh breath.This three flavors Chinese medicine all has antibiotic, antiviral, anti-inflammatory, enhancing immunity, anti-ageing waiting for a long time effect, and honeysuckle is in the prevention canker sore, and mother chrysanthemum also has the effect of uniqueness aspect cardiovascular in protection.
But, cigarette industry when using said herbal medicine, mostly natural Chinese medicinal herb is carried out common solvent extraction after, the extract that obtains is added in cigarette paper or the tobacco leaf, increase cigarette perfume (or spice) to reach, coordinate the effect of flue gas.This traditional extracting method complex process, solvent-oil ratio is big, length consuming time, the yield of active ingredient is lower, and cost is higher relatively.In addition, owing to there is not sterilization process in leaching process, extract can grow assorted bacterium after depositing certain hour, influences product quality, also can produce harm to human body.
Summary of the invention
At the above-mentioned deficiency of prior art, one of purpose of the present invention provides the ultrahigh-pressure extraction method of a kind of honeysuckle, mother chrysanthemum, mulberry leaf, and its yield is higher, and cost is low, not breed bacteria.Another object of the present invention is that the mixed liquor that ultrahigh-pressure extraction method extracted with honeysuckle, mother chrysanthemum, mulberry leaf joins in cigarette paper pulp or the pipe tobacco, utilize that active ingredient reduces the harm of cigarette to human body in the Chinese herbal medicine, make cigarette have clearing heat and detoxicating, clear throat, the promoting production of body fluid and nourishing the lung health care that waits; The suction flavor of mixed extract energy harmony cigarette makes the smoker that comfortable happy sense be arranged.
Technical scheme of the present invention is: the ultrahigh-pressure extraction method of honeysuckle, mother chrysanthemum, mulberry leaf, be that honeysuckle, mother chrysanthemum, mulberry leaf are put into the super-pressure extractor after mixing, add the 60%-95% ethanol (quantity of solvent that common backflow or the extracting method of boiling add is all at least more than 8 times) of 5 times of weight of said mixture; Be pressurized to 100MPa-400MPa, behind the pressurize 8min (common backflow or the minimum 1h-2h of needs of the extracting method of boiling), release immediately; Take out extract and filter while hot, gained filtrate is concentrated into the 20%-30% of original volume after, refrigeration is spent the night; To refrigerate liquid centrifuge centrifugation (with thorough removal protein, polysaccharide and other impurity), rotating speed is that per minute 5000 changes, and the time is 15min, filters, and gained filtrate is the mixed extract of honeysuckle, mother chrysanthemum, mulberry leaf.
Described honeysuckle, mother chrysanthemum, mulberry leaf mixture mix in following ratio: honeysuckle 35-180 part, chrysanthemum 40-195 part, mulberry leaf 20-120 part.
1 ‰-5% the amount of said extracted liquid with cigarette paper pulp weight joined in the cigarette paper pulp; Or join in the pipe tobacco with 0.1 ‰-1% amount of pipe tobacco weight.
Method of the present invention is simple and practical, and is easy to operate, saves time, and cost is low, and the effective component yield height of extraction has utilized raw material resources fully.Sample sterilization behind HTHP is good, can be in lay up period breed bacteria again.Extract of the present invention is made cigarette after joining in pipe tobacco or the cigarette paper pulp, contains multiple effective component to the human body beneficial in this extract, can improve the smoking quality of cigarette, and have plurality of health care functions.
Description of drawings
Accompanying drawing 1 is that the gas chromatography-mass spectrum of extract of the present invention is measured collection of illustrative plates;
Accompanying drawing 2 is high-efficient liquid phase chromatogram spectrums of extract of the present invention.
The specific embodiment
Below in conjunction with embodiment and accompanying drawing relevant technologies problem of the present invention is described in further detail.The method that the present invention sterilizes simultaneously with super-pressure extracts the natural flavor composition of the mixture that natural Chinese medicinal herb honeysuckle, mother chrysanthemum and mulberry leaf are formed, through quantitatively detecting, contrast common extraction method, the yield of the material that plays a major role in the mixed extract of the present invention improves greatly, reduced cost, also utilized raw material resources better, result such as table 1:
Main active ingredient contrast in table 1, the extract
The extract of common extracting method in method of the present invention and the prior art in Bacteria Culture detects, is coated with flat band method by dilution and detects, and both bacteriums detect (seeing Table 2) very inequality.The extract of method preparation of the present invention is owing to killing bacterium fully under ultra-high pressure condition, so can preserve the long period.And common backflow or the extracting method gained extract that boils just had later the bacteriums of different amounts to produce in one month, and product quality reduces along with the prolongation of memory time.
Table 2, period of storage and bacterium colony detect contrast
Embodiment 1: respectively 40 parts on extracting honeysuckle, mother chrysanthemum, mulberry leaf, put into the super-pressure extractor, and add 5 times of amount 60% ethanol, be pressurized to 100MPa, pressurize 8min, release immediately, take out extract and filter while hot, again filtrate is concentrated into 30% of original volume, put into refrigerator cold-storage and spend the night.Filtrate after the refrigeration is used the centrifugal 15min of centrifuge, and rotating speed is that per minute 5000 changes, and refilters, and gained filtrate joins in the cigarette paper pulp with 5 ‰ of cigarette paper pulp weight, makes tobacco product by prior art processes again.
Embodiment 2: respectively 40 parts on extracting honeysuckle, mother chrysanthemum, mulberry leaf, put into the super-pressure extractor, and add 5 times of amount 60% ethanol, be pressurized to 100MPa, pressurize 8min, release immediately, take out extracting liquid filtering, be concentrated into 30% of former extracting liquid volume again, put into refrigerator cold-storage and spend the night, the filtrate after the refrigeration is used the centrifugal 15min of centrifuge, rotating speed is that per minute 5000 changes, refilter, gained filtrate joins in the pipe tobacco with 0.5 ‰ of pipe tobacco weight, makes tobacco product by prior art processes again.
Embodiment 3: 60 parts of extracting honeysuckles, 80 parts of mother chrysanthemums, 50 parts on mulberry leaf, put into the super-pressure extractor, and add 5 times of amount 75% ethanol, be pressurized to 300MPa, pressurize 8min, release immediately, take out extracting liquid filtering, be concentrated into 25% of former extracting liquid volume again, put into refrigerator cold-storage and spend the night, the filtrate after the refrigeration is used the centrifugal 15min of centrifuge, rotating speed is that per minute 5000 changes, refilter filtrate, join in the cigarette paper pulp with 1% of cigarette paper pulp weight, make tobacco product by prior art processes again.
Embodiment 4: 60 parts of extracting honeysuckles, 80 parts of mother chrysanthemums, 50 parts on mulberry leaf, put into the super-pressure extractor, and add 5 times of amount 75% ethanol, be pressurized to 300MPa, pressurize 8min, release immediately, take out extracting liquid filtering, be concentrated into 25% of former extracting liquid volume again, put into refrigerator cold-storage and spend the night, the filtrate after the refrigeration is used the centrifugal 15min of centrifuge, rotating speed is that per minute 5000 changes, refilter filtrate, join in the pipe tobacco with 1 ‰ of pipe tobacco weight, make tobacco product by common tobacco curing technology again.
Embodiment 5: 120 parts of extracting honeysuckles, 80 parts of mother chrysanthemums, 20 parts on mulberry leaf, put into the super-pressure extractor, and add 5 times of amount 95% ethanol, be pressurized to 400MPa, pressurize 8min, release immediately, take out extracting liquid filtering, be concentrated into 20% of former extracting liquid volume again, put into refrigerator cold-storage and spend the night, the filtrate after the refrigeration is used the centrifugal 15min of centrifuge, rotating speed is that per minute 5000 changes, refilter filtrate, join in the cigarette paper pulp with 3% of cigarette paper pulp weight, make tobacco product by prior art processes again.
Embodiment 6: 120 parts of extracting honeysuckles, 80 parts of mother chrysanthemums, 20 parts on mulberry leaf, put into the super-pressure extractor, and add 5 times of amount 95% ethanol, be pressurized to 400MPa, pressurize 8min, release immediately, take out extracting liquid filtering, be concentrated into 20% of former extracting liquid volume again, put into refrigerator cold-storage and spend the night, the filtrate after the refrigeration is used the centrifugal 15min of centrifuge, rotating speed is that per minute 5000 changes, refilter filtrate, join in the pipe tobacco with 5 ‰ of pipe tobacco weight, make tobacco product by prior art processes again.
Embodiment 7: 40 parts of extracting honeysuckles, 50 parts of mother chrysanthemums, 80 parts on mulberry leaf, put into the super-pressure extractor, and add 5 times of amount 70% ethanol, be pressurized to 400MPa, pressurize 8min, release immediately, take out extracting liquid filtering, be concentrated into 20% of former extracting liquid volume again, put into refrigerator cold-storage and spend the night, the filtrate after the refrigeration is used the centrifugal 15min of centrifuge, rotating speed is that per minute 5000 changes, refilter filtrate, join in the cigarette paper pulp with 3% of cigarette paper pulp weight, make tobacco product by prior art processes again.
Embodiment 8: 40 parts of extracting honeysuckles, 50 parts of mother chrysanthemums, 80 parts on mulberry leaf, put into the super-pressure extractor, and add 5 times of amount 70% ethanol, be pressurized to 400MPa, pressurize 8min, release immediately, take out extracting liquid filtering, be concentrated into 20% of former extracting liquid volume again, put into refrigerator cold-storage and spend the night, the filtrate after the refrigeration is used the centrifugal 15min of centrifuge, rotating speed is that per minute 5000 changes, refilter filtrate, join in the pipe tobacco with 5 ‰ of pipe tobacco weight, make tobacco product by prior art processes again.
After mixed extract of the present invention joins in the cigarette, micromolecular volatile oil makes cigarette have pure and fresh simple and elegant unique perfume, in the cigarette combustion process, the extremely strong material of volatility can be cracked into fragrance matters such as micromolecular aldehyde, alcohol, ketone, acid, when not destroying flue gas self style, strengthened the suction flavor of cigarette.And most effective component; all do not have directly to enter human body with flue gas under the ruined state as triterpenes, flavonoids, amino acid etc. in its structure; remove free radical, protection mouth, nasal membrane, pharmacological action such as promoting production of body fluid and nourishing the lung thereby play; to such an extent as to allow the smoker feel joyful sense; as: the assorted gas of flue gas obviously reduces, and the soft exquisiteness of flue gas has the sweet sense of promoting the production of body fluid of tangible profit; the residual eliminating on tongue fur surface, the flue gas property sent out raising thoroughly.
In order to confirm that the active ingredient in the mixed extract of the present invention enters into respiratory tract with flue gas, and produce beneficial effect and make the smoker feel to inhale the happiness sense of flavor, the applicant uses the active ingredient in the dedicated fiber rate sheet collection flue gas, adopt GC/MS to measure volatile ingredient, measurement result as shown in Figure 1.Fig. 1 be gas chromatography-mass spectrum figure (abscissa is a retention time, ordinate represent the relative amount of the composition of measuring in mixture), mensuration be that increase cigarette in the mixed liquor of the present invention is smelt fragrant and jealous volatile ingredient.As showing among Fig. 1 that retention time is that 1.6 minutes composition is a dihydrofuran, content is very high, has significantly roasting fragrant and sweetly, increases the sweet sense of cigarette; Retention time is that 15.87 minutes composition is α-damascenone, content is also quite high, in cigarette, can play the effect of improve significantly flue gas and enrichment flue gas, other volatile ingredients also all have and above-mentionedly similarly improve cigarette and smell fragrant and jealous complementary effect, and content is asked for an interview table 3 with the form demonstration among Fig. 1:
Volatile ingredient and the effect in cigarette thereof in table 3, the mixed extract
| Retention time (min) | Detected material | Effect in cigarette |
| 1.60 | 2, the 3-dihydrofuran | Roasting fragrant and sweet |
| 3.58 | Ethyl cinnamate | More weak is fragrant and sweet |
| 7.90 | Citrene | Soft continuous flue gas, lasting is lasting |
| 13.50 | Menthol | Thorn falls in fine and smooth flue gas |
| 15.87 | α-damascenone | Improve fragrance, the enrichment flue gas |
| 19.76 | Terpinol | Brisk flue gas makes cigarette fragrant bright |
| 23.04 | Nerolidol | Give that flue gas is sweet, the style and features of style, fruital |
| 25.83 | Linalool | Saturating, fine and smooth flue gas, Hui Tian |
| 29.24 | Ethyl maltol | Cover assorted gas, Hui Tian |
| 31.89 | Palmitic acid | Auxiliary other characteristic perfume |
Fig. 2 is that (abscissa is a retention time to high-efficient liquid phase chromatogram; ordinate represents to make into the relative amount of branch in mixture), mensuration be to rise in the mixed liquor of the present invention to improve cigarette and inhale the fixedness composition that flavor and protection oral mucosa, bronchus, reduction cigarette stimulate.As 7.66 minutes the composition of retention time that shows among the figure is galuteolin, and the effect of the cough-relieving of promoting the production of body fluid is arranged; Retention time is that 6.91 minutes composition is a chlorogenic acid, and the spectrum antibacterial action is arranged; Retention time is that 17.19 minutes composition is a linarin, and the effect of anti-inflammatory and releasing smooth muscle spasm is arranged.Other main components also all have similar protection health, the effect of the ill symptoms that minimizing smoking causes.Content is asked for an interview table 4 with the form demonstration among Fig. 2:
Fixedness composition and the effect in cigarette thereof in table 4, the mixed extract
| Retention time (min) | Detected material | Effect in cigarette |
| 4.03 | Sitosterol | The anti-inflammatory sterilization |
| 6.91 | Chlorogenic acid | Broad-spectrum antiseptic |
| 7.66 | Galuteolin | The cough-relieving of promoting the production of body fluid |
| 8.64 | The chrysanthemum glucoside | Wet one's whistle |
| 10.19 | Yejuhua lactone | The removing free radical is antibiotic |
| 12.28 | Artoglasin A | The removing free radical is anti-ageing |
| 16.40 | Inositol | Prevention of arterial is atherosis |
| 17.19 | Linarin | The anti-inflammatory spasmolysis |
| 18.31 | Eucarvone | Expansion bronchus, antiallergy |
| 19.29 | Acaciin | Anti-inflammatory is antibacterial |
| 21.19 | Chrysanthemin | Antitumor, nourish blood and quench the thirst |
| 23.41 | Asparatate | Prevention of cardiac, hypertension |
Smoke panel test through the expert that smokes panel test, mixed extract of the present invention adds in the cigarette, does not only destroy the local flavor of cigarette itself, has also increased the various joyful senses that are of value to smoking, and also can protect health in aspiration procedure, and smoking result sees Table 5:
Table 5, extract of the present invention are applied to the smoking result of cigarette
| Blank cigarette | The cigarette that adds mixed extract of the present invention |
| Astringent taste is very heavy, and the flue gas property sent out thoroughly is not good, and throat stimulates big, and lingual surface has residual | Smell perfume (or spice) and greatly enrich, the flue gas property sent out thoroughly has very big raising, can improve the stimulation of the assorted gas of flue gas to oral cavity and throat well, makes the soft exquisiteness of flue gas, the sweet sense of promoting the production of body fluid of tangible profit is arranged, the lingual surface noresidue. |
Claims (2)
1. the ultrahigh-pressure extraction method of a honeysuckle, mother chrysanthemum, mulberry leaf, it is characterized in that: honeysuckle, mother chrysanthemum, mulberry leaf are mixed in following ratio: honeysuckle 35-180 part, chrysanthemum 40-195 part, mulberry leaf 20-120 part, put into the super-pressure extractor after the mixing, add the 60%-95% ethanol of 5 times of amounts of said mixture gross weight; Be pressurized to 100MPa-400MPa, behind the pressurize 8min, release immediately; Take out extracting liquid filtering, gained filtrate is concentrated into the 20%-30% of original volume, refrigeration is spent the night; Filtrate after the refrigeration is used the centrifuge centrifugation, and rotating speed is that per minute 5000 changes, and the time is 15min, filters, and gained filtrate is the mixed extract of honeysuckle, mother chrysanthemum, mulberry leaf.
2. the application of the extract that makes of a ultrahigh-pressure extraction method as claimed in claim 1 is characterized in that: 1 ‰-5% the amount of described extract with cigarette paper pulp weight joined in the cigarette paper pulp; Or join in the pipe tobacco with 0.1 ‰-1% amount of pipe tobacco weight.
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| CN101843364B (en) * | 2010-02-26 | 2012-09-05 | 湖北中烟工业有限责任公司 | Spice additive for natural cigarettes and preparation method thereof |
| CN102771862A (en) * | 2012-07-23 | 2012-11-14 | 广东省农业科学院蚕业与农产品加工研究所 | Preparation method and application of mulberry leaf phenolic acid extract with antibacterial activity |
| GB201213870D0 (en) | 2012-08-03 | 2012-09-19 | British American Tobacco Co | Tobacco extract, preparation thereof |
| CN102952639B (en) * | 2012-11-13 | 2014-09-10 | 广东中烟工业有限责任公司 | Preparation method of tobacco endogenous perfume and application thereof |
| CN103710149B (en) * | 2013-12-30 | 2015-06-10 | 湖南先伟实业有限公司 | Wild chrysanthemum extract and taraxacum extract matched tobacco flavor, preparation method and application thereof |
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| CN109938396B (en) * | 2019-03-28 | 2021-06-08 | 江西中烟工业有限责任公司 | Preparation method of tobacco endogenous Maillard reaction spice and application of tobacco endogenous Maillard reaction spice in novel tobacco products |
| CN110279739B (en) * | 2019-06-25 | 2022-07-01 | 云南中烟工业有限责任公司 | Application of wild chrysanthemum extract in preparation of medicine or health-care product for preventing and treating oral epithelial cell death caused by mouth tobacco |
| CN114304338A (en) * | 2021-12-30 | 2022-04-12 | 北京康益药业有限公司 | Preparation method of fresh flower leaf beverage for preventing cold |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1051489A (en) * | 1989-11-08 | 1991-05-22 | 沈阳市北方生物技术研究所 | The preparation method of natural quick-dissolving haw tea |
| CN1094915A (en) * | 1993-05-11 | 1994-11-16 | 辽宁大学 | With the Semen Crataegi is the processing method of feedstock production beverage, oil plant and gac |
| CN1384088A (en) * | 2002-05-21 | 2002-12-11 | 杨建文 | Extraction process of resveratrol from giant knotweed |
| CN1467273A (en) * | 2002-07-11 | 2004-01-14 | 李定中 | Extraction process of nimbin oil |
-
2007
- 2007-11-28 CN CN2007101685082A patent/CN101444331B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1051489A (en) * | 1989-11-08 | 1991-05-22 | 沈阳市北方生物技术研究所 | The preparation method of natural quick-dissolving haw tea |
| CN1094915A (en) * | 1993-05-11 | 1994-11-16 | 辽宁大学 | With the Semen Crataegi is the processing method of feedstock production beverage, oil plant and gac |
| CN1384088A (en) * | 2002-05-21 | 2002-12-11 | 杨建文 | Extraction process of resveratrol from giant knotweed |
| CN1467273A (en) * | 2002-07-11 | 2004-01-14 | 李定中 | Extraction process of nimbin oil |
Non-Patent Citations (3)
| Title |
|---|
| 张守勤，王长征.常温超高压中药有效成分提取技术.《第六届全国药用植物和植物药学术研讨会》.2006,正文第224-226页. * |
| 张格等.采用超高压技术从茶叶中提取茶多酚.《茶叶科学》.2006,第26卷(第4期),摘要,正文第291-294页. * |
| 李宏伟等.超高压提取山楂叶中黄酮类化合物.《吉林大学学报(工学版)》.2006,第36卷(第3期),正文第438-442页. * |
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