CN101433651A - Plaster for treating painful swelling - Google Patents
Plaster for treating painful swelling Download PDFInfo
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- CN101433651A CN101433651A CNA2007100190453A CN200710019045A CN101433651A CN 101433651 A CN101433651 A CN 101433651A CN A2007100190453 A CNA2007100190453 A CN A2007100190453A CN 200710019045 A CN200710019045 A CN 200710019045A CN 101433651 A CN101433651 A CN 101433651A
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- plaster
- radix
- rhizoma
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- herba
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- 239000011505 plaster Substances 0.000 title claims abstract description 30
- 230000008961 swelling Effects 0.000 title claims abstract description 18
- 239000003814 drug Substances 0.000 claims abstract description 41
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 17
- 208000010392 Bone Fractures Diseases 0.000 claims abstract description 14
- 241000222336 Ganoderma Species 0.000 claims abstract description 12
- 239000002674 ointment Substances 0.000 claims abstract description 7
- 206010003246 arthritis Diseases 0.000 claims abstract description 6
- 238000000605 extraction Methods 0.000 claims abstract description 5
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 238000003756 stirring Methods 0.000 claims description 20
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 241000746375 Andrographis Species 0.000 claims description 11
- 241000717739 Boswellia sacra Species 0.000 claims description 11
- 239000004863 Frankincense Substances 0.000 claims description 11
- 241001057584 Myrrha Species 0.000 claims description 11
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 10
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- 229940079593 drug Drugs 0.000 claims description 6
- 239000002552 dosage form Substances 0.000 claims description 5
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 4
- 235000011837 pasties Nutrition 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 238000005516 engineering process Methods 0.000 claims description 3
- ZEMPKEQAKRGZGQ-AAKVHIHISA-N 2,3-bis[[(z)-12-hydroxyoctadec-9-enoyl]oxy]propyl (z)-12-hydroxyoctadec-9-enoate Chemical compound CCCCCCC(O)C\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CC(O)CCCCCC)COC(=O)CCCCCCC\C=C/CC(O)CCCCCC ZEMPKEQAKRGZGQ-AAKVHIHISA-N 0.000 claims description 2
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- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 2
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- 241000245665 Taraxacum Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
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- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to cataplasmata, namely a swelling pain eliminating plaster, which is used for treating bone fracture, bone diseases, arthritis, and surgical sores and ulcers, and is prepared from pure traditional Chinese medicines. Nineteen traditional Chinese medicine raw materials such as dandelion, radix puerariae, rhizoma drynariae, Cortex Ilicis Rotundae, Japan Yam Rhizome, glossy ganoderma are used for prescription; the traditional Chinese medicine raw materials are crushed first, are extracted through methods such as water extraction and alcohol extraction respectively, and are condensed into a thick ointment shape; and an excipient is added to be prepared into the latest cataplasm type traditional Chinese medicine ointment. Through the clinical observation, the plaster has functions of strengthening body resistance such as promoting blood circulation and removing blood stasis, dredging the channels, reducing swelling and relieving pain, removing blood stasis and toxic substances, and reuniting bones to human bodies, ensures that the qi and blood of the human bodies operate normally, makes the pain disappear due to the fact that no pain exists when the human bodies are smooth, removes blood stasis and toxic substances, and prevents the change caused by persistent injuries. Therefore, during the treatment of traumatic fracture, the plaster relieves pain, promotes the formation of poromas in times, can greatly shorten the healing period of bone fracture, and can prevent various disadvantages caused by stopping the natural healing of bone fracture patients. The plaster can improve bone substance, eliminate the necrosis, and has functions of removing blood stasis and toxic substances, so the plaster has healing effect on diseases such as osteomyelitis, bone necrosis, bone tuberculosis and late cancer pain. The plaster has remarkable treatment effect on various osteoarthropathies such as rheumatoid diseases and bone regeneration.
Description
One, technical field
The pure Chinese medicine that the present invention relates to a kind of set a broken bone, osteopathia, arthritis, boil is made cataplasma---plaster for treating painful swelling.
Two,
Existing medical skill, to the no specific short of fracture, mainly be operative reduction after, dependence normal healing, but the time is long, sees sequela more.Though arthritis, rheumatoid, bone regeneration, intervertebral disk hernia, gout have the equal difficulty of many medicaments of oral administration and externally to reach late result, more refractory more.Furuncle furuncle carbuncle application compress do not have specific short.External application acupuncture point medical treatment internal organs miscellaneous diseases does not also have the specially good effect application compress.
Though Ancient Times in China has a large amount of Dressed plasters, majority all contains drug toxicity, untoward reaction often occurs.Simultaneously traditional oil extractum, too high because of the oil temperature in the fry extractive process, can cause some effective active composition forfeitures in the medicine, and also be difficult on the lagging skin cleaning; Effective ingredient discharges also slow.Modern rubber plaster, content of dispersion is few, and compatibility is not good enough, and produce effects is poor.The cataplasma kind is promoted relatively poor, and Chinese medicine patcher is disunity also, and its content of dispersion is few, and general content of dispersion is 1/10～20, and pastille affects the treatment at least.Influence is pasted at most, is difficult to select an amount of compatibility.
Three, summary of the invention
The pure Chinese medicine that the purpose of this invention is to provide a kind of set a broken bone, osteopathia, arthritis, boil is made cataplasma---plaster for treating painful swelling.It is according to long-term a large amount of clinical experience specially good effect sides medicine, in conjunction with scientific research, and a kind of pure Chinese medicinal preparation external specific drug of drafting.Be a kind of on the basis that guarantees curative effect, optimize dosage form, select the cataplasma compatibility dosage form that adapts to the most.
It is special effect that the present invention has one, can cure the disease, and can keep fit again, i.e. " eliminating pathogenic factor for supporting vital QI ".Non-general dispeling the wind pulled out cold, and the plaster that pursues the numbness class can reach.These application compress can fully show the multi-functional characteristics---i.e. " Chinese medicine nature and flavor---prescription---polymolecular comprehensive effect " that cure mainly of Chinese medicine more simultaneously.The 2nd, in the cataplasma type of intending certainly, adopted the Release Performance height, can use repeatedly, it is comfortable that external application is felt, ductility is arranged, and main is to have changed the easy sensitization of exterior patch in the past, does not almost have sensitization.The 3rd, this patch medicine exceeds several times than the content of dispersion of conventional cataplasma, has improved curative effect, has distinctive feature.
Plaster for treating painful swelling external application medicine provided by the invention has been given full play to the characteristic of " treating the same disease with different methods, the treating different diseases with the same therapeutic principle " of the traditional Chinese medical science, and has been developed a kind of outer emplastrum simultaneously, can adapt to the treatment of multiple disease, can not only eliminate muscles and bones, joint, body surface inflammation.The internal organs miscellaneous diseases can be recuperated under medical treatment in the external application acupuncture point simultaneously.Paste SHANZHONG acupoint, XINYU acupoint as angina pectoris; Stomachache vomiting and dirarrhea disease is pasted umbilicus, ZHONGWAN acupoint, can pain relieving remove disease, and the middle part of gastric cavity is pasted in the cholecystitis acute attack, and liver and gall Yu sticks in the cave and can alleviate distension severe pain immediately.And have no side effect.
Task of the present invention is to finish like this, and it is to be equipped with the externally used paste that the cataplasma type is made by the medicament that following raw materials by weight proportions is made, and wherein the medicament made from the materials of weight proportions medicine is:
Radix Puerariae 10--40 Rhizoma Drynariae 10--30 Thunder Gods are risen 10--30 and are born public affairs and rise 15--35
Herba Andrographis 10--30 Herba Taxilli 15--50 cattle sunset 10--30 Lignum Dalbergiae Odoriferae 5--15
Radix Scutellariae 6--15 Radix Et Rhizoma Rhei 6--15 Olibanum 6--15 Myrrha 6--15
Sea snake 5--30 Ganoderma 10--30 Herba speranskiae tuberculatae 15--30 Rhizoma Dioscoreae Nipponicae 15--30
Rhizoma Chuanxiong 3--15 Cortex Ilicis Rotundae 10--20 Borneolum Syntheticum 0.5--2
The preferred weight proportioning of the prescription of preparation medicine of the present invention is:
Radix Puerariae 15--35 Rhizoma Drynariae 15--25 Thunder God is risen 15--30 and is born public affairs and rise 20--30
Herba Andrographis 15--25 Herba Taxilli 15--40 cattle sunset 15--30 Lignum Dalbergiae Odoriferae 8--15
Radix Scutellariae 8--15 Radix Et Rhizoma Rhei 8--15 Olibanum 8--15 Myrrha 8--15
Sea snake 8--25 Ganoderma 12--25 Herba speranskiae tuberculatae 20--30 Rhizoma Dioscoreae Nipponicae 20--30
Rhizoma Chuanxiong 6--10 Cortex Ilicis Rotundae 12--20 Borneolum Syntheticum 1--1.5
The optimum weight proportioning of the prescription of preparation medicine of the present invention is::
Radix Puerariae 20--30 Rhizoma Drynariae 15--20 Thunder God is risen 20--30 and is born public affairs and rise 25--30
Herba Andrographis 10--20 Herba Taxilli 15--30 cattle sunset 10--30 Lignum Dalbergiae Odoriferae 10--15
Radix Scutellariae 10--15 Radix Et Rhizoma Rhei 10--15 Olibanum 10--15 Myrrha 10--15
Sea snake 10--15 Ganoderma 15--20 Herba speranskiae tuberculatae 25--30 Rhizoma Dioscoreae Nipponicae 25--30
Rhizoma Chuanxiong 8--10 Cortex Ilicis Rotundae 15--20 Borneolum Syntheticum 1--1.3
Optimum implementation of the present invention is:
Radix Puerariae 30 Rhizoma Drynariae 20 Thunder Gods are risen 20 and are born public affairs and rise 30 Herba Andrographis 15
20 Ns of sunset of Herba Taxilli 15 Lignum Dalbergiae Odoriferae, 10 Radix Scutellariaes, 10 Radix Et Rhizoma Rhei 10
Olibanum 10 Myrrhas 10 sea snakes 10 Ganodermas 20 Herba speranskiae tuberculataes 30
Rhizoma Dioscoreae Nipponicae 25 Rhizoma Chuanxiongs 10 Cortex Ilicis Rotundaes 15 Borneolum Syntheticums 1
Above-mentioned each component is made production technology of the present invention is:
1) get Solenognathus, clean drying, superfine grinding. standby;
2) Borneolum Syntheticum ethanol dissolves, and is standby;
3) Radix Puerariae in the side, fall true, Ganoderma, Olibanum, Myrrha, Solenognathus etc. and be ground into fine powder respectively, mix, add 6 times ethanol, the extraction of heating each 2 hours, leaches pure liquid, three times so repeatedly, it is standby to regain pure liquid, all the other residues is carried medicine with water put the continuation extraction;
4) wherein Rhizoma Drynariae, Thunder God are risen, Radix Ophiopogonis rises, Herba Andrographis, Herba Taxilli, Radix Dipsaci, Niu Xi, fall true, Radix Et Rhizoma Rhei, Radix Scutellariae, Herba speranskiae tuberculatae, Rhizoma Dioscoreae Nipponicae, Rhizoma Chuanxiong etc. and be ground into coarse powder, water is carried three times. first, secondary is fried in shallow oil respectively and is carried 3 hours. and fry in shallow oil for three times and to carry 2 hours, collect medicinal liquid, the elimination medicinal residues, precipitation is got supernatant, and is standby;
5) its water extract being concentrated the thick paste shape and fully mix, in mixing, add Solenognathus micropowder and dissolve with ethanol Borneolum Syntheticum liquid with the concentrated thick paste shape of pure liquid. also further fully mix homogeneously is advisable, and is standby. and this pure Chinese medicine unguentum becomes.Its weight is middle dose 1/6.It is 6g that every gram cream contains Biomass;
6) the pure Chinese medicine unguentum that will make is made the novel patch of cataplasma type:
A, elder generation add water 50ml to agitator stirs, and adds card ripple pool 5g and fully stir in stirring, in the pasty state;
B adds the plaster thick paste fully stirring again;
C adds 0.5ml water with NaOH 0.004g and mixes to add and be used as medicine, and to transfer pH value be 6-7;
D adds triethanolamine 1ml and propylene glycol 2ml and glycerol 3mI mixing again, adds to stir;
After e adds glycerol 5ml and magnesium stearate 1g and ethanol mixing again, add and stir;
F adds sodium carboxymethyl cellulose 2g again and fully mixes in the pasty state with water 6ml, adds to stir;
G adds Ni Baijin again: methyl ester 0.004g and ethyl ester 0.004g grind well, and with Oleum Ricini 5ml mixing, add and stir;
H adds that weight is 1g behind tween 61 60% and polysorbate60 40% mixing again, adds fully and stirs;
I mixes abundant the stirring with it and is starchiness, and is dry appropriate through the coating placement, makes cataplasma type patch again, and dosage form specification 0.9 * 11.2cm/ pastes, and containing weight is 3g.
Medicament of the present invention provides a kind of state-of-the art Chinese medicinal ointment dosage form of uniqueness.With Radix Puerariae, Formica fusca is monarch in the prescription of the present invention, the saturating skin expelling pathogenic factors from muscles of energy, and tendons relaxing and meridians dredging, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, the liver and the kidney tonifying, strong muscles and bones, QI invigorating is kept fit.With parasitism, Radix Dipsaci, Niu Xi, Ganoderma, sea snake is minister, with benefit Liver and kidney, strengthening bone and muscle, fill blood, promote tissue repair (comprising nerve, skin, muscles and bones, mucosa etc.), enhance immunity function.And multisystem there is regulating action.With Caulis Lonicerae, Herba Andrographis, Radix Scutellariae, Radix Et Rhizoma Rhei, Rhizoma Dioscoreae Nipponicae etc. is assistant, to strengthen heat-clearing and toxic substances removing, damp eliminating removing blood stasis, dredge the meridian passage, mass dissipating and swelling eliminating.For making, have the dredge the meridian passage of being good at, promoting flow of QI and blood, harmonizing yingfen and weifen with medicines such as Herba speranskiae tuberculatae, Olibanum, Myrrha, Zaocys, Lignum Dalbergiae Odoriferae, Rhizoma Chuanxiong, Borneolum Syntheticums, and can impel this medicine to reach muscles and bones hundred joints thoroughly, interior to internal organs, outer skin, the fur of reaching do not reach, nowhere less than effect nowhere.Therefore,, the disease of joint, muscles and bones, skin can be controlled, also point-application can be passed through though the present invention is an external plaster application agent, by the meridians effect, medical treatment internal organs miscellaneous diseases.
The novel patch of the used cataplasma type of the present invention adapts to the skin environment, and approximate skin ph value adapts with shell temperature, and with Transdermal absorption, the drug effect performance is thorough, and controlled capability can continue to play a role.Stick body surface and feel comfortably cool, flexibility is good, and ductility is arranged, and can paste usefulness repeatedly.Efficient 48 hours phases, persistence effect duration is 72 hours, and more this patch instant effect can paste and can effect a radical cure its disease, for a long time with no fraud.And there is not any toxin, no sensitization have uniqueness than general patch advantage.
Plaster for treating painful swelling provided by the invention proves through toxicological test and pharmacodynamic analysis:
Toxicological experiment, 1, do not have a significantly irritated effect; 2, anxious poison test does not see that through evidences such as depilation, damaged skin, mouthful administration gastrointestinal absorptions obvious poisoning symptom takes place.
Pharmacodynamic analysis, 1, swelling has the obvious suppression effect to mice auricular concha inflammation; 2, the high, medium and low three dosage groups of this plaster all can obviously improve mice pressure tail method pain threshold, and are better than positive controls; 3,, prove the high, medium and low dosage external of this plaster mice mesentery microcirculation that has clear improvement to the microcirculatory experiment of mesentery; 4, this plaster phase of union of fracture mutually in, can obviously accelerate chondrocyte and be converted into bone and its cells, promptly begin to ossify; Periosteal reaction after accelerating to fracture and broken ends of fractured bone organization of hematoma and new bone formation; Accelerate absorption, the transformation of the broken osteocomma of fracture end; Promote callus formation and sclerotin repair process, and obviously be better than the positive control drug group.5, this plaster has certain therapeutical effect .6, this plaster that the generation of staphylococcus aureus is had certain inhibitory action to the rabbit acute osteomyelitis model that duplicates with staphylococcus aureus.
The present invention is through the observation of clinical 416 example treatments, for diseases such as cancer pain, bone tuberculosis, osteomyelitis, paronychia, wound, fracture, wound hematoma, arthritis, bone regeneration, sciatica, lumbago, headache, stomachache, adnexitis, prostate hyperplasia, clinical treatment adopts this plaster of external application that positive effect or cured person 151 examples are arranged for 1 time, 2 times 72 examples, 3 times 131 examples, 4 times 10 examples, 5 times 5 examples, 7 times 5 examples, 8 times 10 examples, 10 times 10 examples, 14 times 6 examples, recovery from illness 382 examples in 416 examples, produce effects 17 examples, effective 8 examples, invalid 9 examples, total effective rate is 98%.According to clinical observation, this plaster has blood circulation promoting and blood stasis dispelling to human body, dredging the meridian, and reducing swelling and alleviating pain, dissolving blood stasis and detoxication, the effect that diffusing wounds such as continuous muscle long bone are set upright makes the human qi and blood running normal, and " general rule is not bitterly " disappears pain, eliminates stasis of blood poison, prevents to hinder and changes for a long time.Therefore in traumatiing fracture treatment, this medicine has pain relieving and promotion callus formation at double, and can shorten fracture greatly and heal the phase, and the many drawbacks that can prevent the fracture patient normal healing to occur.Because of it can improve sclerotin, eliminate necrosis, and the effect of dissolving blood stasis and detoxication is arranged, then to osteomyelitis, necrosis of bone, bone tuberculosis, diseases such as ache in late cancer have the healing effect.To rheumatoid, the many osteoarthrosis of bone regeneration have significant curative effect.So its indication is wide.No matter be toxicological test, pharmacodynamic analysis; Still when participating in the cintest bed checking has shown that all this medicine is strictly that the curative effect height produces effects fast and has and controls the difficult sick advantage of orthopaedics.
Claims (6)
1, the external used medicine plaster for treating painful swelling of the pure Chinese medicine of a kind of set a broken bone, osteopathia, arthritis, boil, it is characterized in that: it is to be equipped with the externally used paste that the cataplasma type is made by the medicament that following raw materials by weight proportions is made, and wherein the medicament made from the materials of weight proportions medicine is:
Radix Puerariae 10--40 Rhizoma Drynariae 10--30 Thunder Gods are risen 10--30 and are born public affairs and rise 15--35
Herba Andrographis 10--30 Herba Taxilli 15--50 cattle sunset 10--30 Lignum Dalbergiae Odoriferae 5--15
Radix Scutellariae 6--15 Radix Et Rhizoma Rhei 6--15 Olibanum 6--15 Myrrha 6--15
Sea snake 5--30 Ganoderma 10--30 Herba speranskiae tuberculatae 15--30 Rhizoma Dioscoreae Nipponicae 15--30
Rhizoma Chuanxiong 3--15 Cortex Ilicis Rotundae 10--20 Borneolum Syntheticum 0.5--2
2, plaster for treating painful swelling as claimed in claim 1 is characterized in that wherein the weight proportion of each crude drug is:
Radix Puerariae 15--35 Rhizoma Drynariae 15--25 Thunder God is risen 15--30 and is born public affairs and rise 20--30
Herba Andrographis 15--25 Herba Taxilli 15--40 cattle sunset 15--30 Lignum Dalbergiae Odoriferae 8--15
Radix Scutellariae 8--15 Radix Et Rhizoma Rhei 8--15 Olibanum 8--15 Myrrha 8--15
Sea snake 8--25 Ganoderma 12--25 Herba speranskiae tuberculatae 20--30 Rhizoma Dioscoreae Nipponicae 20--30
Rhizoma Chuanxiong 6--10 Cortex Ilicis Rotundae 12--20 Borneolum Syntheticum 1--1.5
3, plaster for treating painful swelling as claimed in claim 1 is characterized in that wherein the weight proportion of each crude drug is:
Radix Puerariae 20--30 Rhizoma Drynariae 15--20 Thunder God is risen 20--30 and is born public affairs and rise 25--30
Herba Andrographis 10--20 Herba Taxilli 15--30 cattle sunset 10--30 Lignum Dalbergiae Odoriferae 10--15
Radix Scutellariae 10--15 Radix Et Rhizoma Rhei 10--15 Olibanum 10--15 Myrrha 10--15
Sea snake 10--15 Ganoderma 15--20 Herba speranskiae tuberculatae 25--30 Rhizoma Dioscoreae Nipponicae 25--30
Rhizoma Chuanxiong 8--10 Cortex Ilicis Rotundae 15--20 Borneolum Syntheticum 1--1.3
4, plaster for treating painful swelling as claimed in claim 1 is characterized in that wherein the weight proportion of each crude drug is:
Radix Puerariae 30 Rhizoma Drynariae 20 Thunder Gods are risen 20 and are born public affairs and rise 30 Herba Andrographis 15
20 Ns of sunset of Herba Taxilli 15 Lignum Dalbergiae Odoriferae, 10 Radix Scutellariaes, 10 Radix Et Rhizoma Rhei 10
Olibanum 10 Myrrhas 10 sea snakes 10 Ganodermas 20 Herba speranskiae tuberculataes 30
Rhizoma Dioscoreae Nipponicae 25 Rhizoma Chuanxiongs 10 Cortex Ilicis Rotundaes 15 Borneolum Syntheticums 1
5, plaster for treating painful swelling as claimed in claim 1 is characterized in that making production technology of the present invention and is:
(1), get Solenognathus, cleaning, drying, superfine grinding. standby;
(2), Borneolum Syntheticum ethanol dissolves, and is standby;
(3), Radix Puerariae in the side, fall true, Ganoderma, Olibanum, Myrrha, Solenognathus etc. and be ground into fine powder respectively, mix, add 6 times ethanol, the extraction of heating each 2 hours, leaches pure liquid, three times so repeatedly, it is standby to regain pure liquid, all the other residues is carried medicine with water put the continuation extraction;
(4), wherein Rhizoma Drynariae, Thunder God are risen, Radix Ophiopogonis rises, Herba Andrographis, Herba Taxilli, Radix Dipsaci, Niu Xi, fall true, Radix Et Rhizoma Rhei, Radix Scutellariae, Herba speranskiae tuberculatae, Rhizoma Dioscoreae Nipponicae, Rhizoma Chuanxiong etc. and be ground into coarse powder, water is carried three times. first, secondary is fried in shallow oil respectively and is carried 3 hours. and fry in shallow oil for three times and to carry 2 hours, collect medicinal liquid, the elimination medicinal residues, precipitation is got supernatant, and is standby;
(5), its water extract being concentrated the thick paste shape and fully mix adding Solenognathus micropowder and dissolve with ethanol Borneolum Syntheticum liquid in mixing with the concentrated thick paste shape of pure liquid. also further fully mix homogeneously is advisable, and is standby. and this pure Chinese medicine unguentum becomes.Its weight is dose 1/6.It is 6g that every gram cream contains Biomass.
6,, it is characterized in that the technology of the pure Chinese medicine unguentum of making being made the cataplasma type is as claim 1,5 described plaster for treating painful swelling:
To agitator add water 50ml and stir, in stirring, add card ripple pool 5g and fully stir, in the pasty state (1), earlier.
(2), again the plaster thick paste is added fully stirring.
(3), add 0.5ml water with NaOH0.004g and mix to add and be used as medicine, the accent pH value is 6--7.
(4), again add triethanolamine 1ml and propylene glycol 2ml and glycerol 3mI mixing, add and stir.
(5), again after adding glycerol 5ml and magnesium stearate 1g and ethanol mixing, add and stir.
(6), again add sodium carboxymethyl cellulose 2g and fully mix in the pasty state, add and stir with water 6ml.
(7), again add Ni Baijin: methyl ester 0.004g and ethyl ester 0.004g grind well, and with Oleum Ricini 5ml mixing, add and stir.
(8), again add that weight is 1g behind tween 6160% and polysorbate60 40% mixing, add fully and stir.
(9), it mixed fully to stir be starchiness, place dry appropriateness through coating, make cataplasma type patch again, dosage form specification 0.9 * 11.2cm/ pastes, containing weight is 3g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100190453A CN101433651A (en) | 2007-11-12 | 2007-11-12 | Plaster for treating painful swelling |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100190453A CN101433651A (en) | 2007-11-12 | 2007-11-12 | Plaster for treating painful swelling |
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| Publication Number | Publication Date |
|---|---|
| CN101433651A true CN101433651A (en) | 2009-05-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007100190453A Pending CN101433651A (en) | 2007-11-12 | 2007-11-12 | Plaster for treating painful swelling |
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| Country | Link |
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| CN (1) | CN101433651A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102008536A (en) * | 2010-12-02 | 2011-04-13 | 吴江迪星科技有限公司 | Tripterygium wilfordii hook extract cataplasm and preparation method thereof |
| CN102698041A (en) * | 2012-06-27 | 2012-10-03 | 上海中医药大学附属龙华医院 | Traditional Chinese medicine compound gel for externally treating cancer pain and preparation method for same |
| CN104998131A (en) * | 2015-09-03 | 2015-10-28 | 丁耀龙 | Composition for promoting healing of injured bone and preparation method thereof |
-
2007
- 2007-11-12 CN CNA2007100190453A patent/CN101433651A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102008536A (en) * | 2010-12-02 | 2011-04-13 | 吴江迪星科技有限公司 | Tripterygium wilfordii hook extract cataplasm and preparation method thereof |
| CN102008536B (en) * | 2010-12-02 | 2012-05-23 | 吴江迪星科技有限公司 | Tripterygium wilfordii hook extract cataplasm and preparation method thereof |
| CN102698041A (en) * | 2012-06-27 | 2012-10-03 | 上海中医药大学附属龙华医院 | Traditional Chinese medicine compound gel for externally treating cancer pain and preparation method for same |
| CN102698041B (en) * | 2012-06-27 | 2013-08-28 | 上海中医药大学附属龙华医院 | Traditional Chinese medicine compound gel for externally treating cancer pain and preparation method for same |
| CN104998131A (en) * | 2015-09-03 | 2015-10-28 | 丁耀龙 | Composition for promoting healing of injured bone and preparation method thereof |
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Open date: 20090520 |