CN101428097A - Psoriasis treating Chinese medicine preparation and its preparing process - Google Patents
Psoriasis treating Chinese medicine preparation and its preparing process Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating psoriasis and a preparation method thereof, the traditional Chinese medicine is prepared by dried rehmannia root, tree peony bark, cortex lycii, red paeony root, common threewingnut root, Mongolian snakegourd root, honeysuckle flower, weeping forsythiae capsule, sinkiang arnebia root, densefruit pittany root-bark, peppermint, rhubarb, liquoric root, belvedere fruit, incised notopterygium rhizome, myrrh and towel gourd vegetable sponge by compatibility according to a certain proportion; the traditional Chinese medicine preparation has the advantages that the medicine has scientific compatibility and comprehensive functions, selects the medicines with the effects of activating blood circulation, cooling blood, eliminating heat and removing dampness to assemble damp pathogenic virus in vivo at the exterior, then uses the medicines with the effects of clearing heat, removing toxin, removing blood stasis and removing freckles to centralizedly remove the virus and uses the medicines with the effects of moistening skin, relieving itch, dredge channels and activating collaterals to promote the regeneration of healthy skin; the medicine can effectively eliminate a variety of virus and pathogenic bacteria, inhibit the invasion of pathogenic microorganisms, improve the microcirculation of the exterior at the same time of removing pathogen and toxin, improve the body immunity and further obtain a lasting efficacy; another major advantage of the medicine is small toxicity and side effects, thereby not causing any harm to liver, kidney and lymphatic system.
Description
Technical field
The present invention relates to a kind of psoriatic Chinese medicine preparation that is used for the treatment of, the invention still further relates to a kind of preparation method of this Chinese medicine preparation.
Background technology
Psoriasis is a kind of common chronic erythema squama, inflammatory skin disease, because its sickness rate height, the course of disease is long, can constitute serious threat to patient's physical and mental health, thereby effective Therapeutic Method of inquiring into this disease is one of emphasis research topic in the current department of dermatologry field.
The psoriatic cause of disease and pathogenesis are comparatively complicated, and Chinese medicine thinks that itself and six climate exopathogens are invaded all multi-pathogenesis such as skin, internal injury caused by excess of seven emotions, eating and drinking without temperance, QI and blood are not normal, the prosperity and decline of zang-fu disharmony regulating YIN and YANG, pathogenesis is relevant.Modern medicine thinks that then this disease and inherited genetic factors, spirit and neural factor, infective agent, immune factor, microcirculatory change, biochemical change and cutin form, and cellular metabolism, dysregulation etc. all have relation.But its definite pathogeny is still clear and definite not enough so far.
According to the applicant's clinical observation for many years, the psoriatic is in case after being made a definite diagnosis, its mental burden is often all heavier, and emotion is how pessimistic and worried, all is to seek medical advice everywhere usually.Because it is also very lack of standardization for the treatment of this disease both at home and abroad; doctor's method rule of treatment of each family also exists great difference; therefore; the patient usually can be taken the oral and external applied medicine that some toxic and side effects are big, zest is strong by misleading; not only the state of an illness fails thoroughly to improve, and the other parts of health but have been subjected to very big infringement on the contrary.
Oral and external application medicine in the market is various in style, really there are many medicines fair for the psoriatic short term effect of treatment, but the toxic and side effects of many medicines wherein is very big, take the back liver, kidney, lymph node are produced certain influence, can also cause leukopenia easily, blood platelet reduction, a lot of diseases can recur after drug withdrawal at once.The patient who also has because of the too fast or unexpected drug withdrawal of decrement, makes the state of an illness accelerate to recur and increase the weight of because of widely applying steroid hormone class medicine, produces different drug-resistant capability and tolerance in the body, very easily brings out pustular type and erythrodermic psoriasis.The low grade fever hyperpyrexia appears, the erythra generation intensive that has, shallow, the little pus bubble of aseptic, the finger that has (toe) joint, congestion and swelling pain, limitation of activity, ankylosis distortion.Have because of former skin lesion enlarges, invade profit and deepen, skin is cracked from dryness, and is hemorrhage, leukocyte raises, symptoms such as each lymphadenectasis, very person's threat to life.Therefore, improve the therapeutic effect of such medicine, and reduce the main goal of attack that the effect of paying of its poison to human body obviously is current psoriasis research.
Summary of the invention
The technical solution adopted for the present invention to solve the technical problems is: this Chinese medicine preparation is to adopt following raw material components and weight portion proportioning to be prepared from.
Radix Rehmanniae 15---30 part Cortex Moutan 15---30 part Cortex Lycii 15---30 part
Radix Paeoniae Rubra 10---25 part Radix Tripterygii Wilfordii 10---30 part Radix Trichosanthis 8---20 part
Flos Lonicerae 10---20 part Fructus Forsythiae 10---20 part Radix Arnebiae (Radix Lithospermi) 10---20 part
Cortex Dictamni 10---20 part Herba Menthae 10---20 part Radix Et Rhizoma Rhei 8---15 part
Radix Glycyrrhizae 8---15 part fructus kochiae 10---15 part Rhizoma Et Radix Notopterygii 10---15 part
Myrrha 3---10 part Retinervus Luffae Fructus 15---35 part
Below be the property of medicine effect of above-mentioned all medicines:
The Radix Rehmanniae: property hardship, cold, clearing away heat and cooling blood, class's rash carbuncle, osteopyrexia and fever, body fluid are done few.Modern medicine determines it and contains various trace elements.
Cortex Moutan: the property hardship, be slightly cold, GUIXIN, liver, kidney, clearing away heat and cooling blood, dissipating blood stasis blood, calentura is sent out speckle, and infantile convulsion is told the nosebleed hematochezia, amenorrhea, acute appendicitis.It has antiinflammatory, resistance attitude, the effect of resisting pathogenic microbes modern study.
Cortex Lycii: bitter cold, return lung, liver, kidney, removing heat from blood clearing away lung-heat, the swollen malignant boil of pain: cough is spitted blood, and dysphoria with smothery sensation is quenched one's thirst, and osteopyrexia and fever, modern study find that its root bark contains cinnamic acid and multiple aldehydes matter and betaine, has analgesic blood sugar reducing function.
Retinervus Luffae Fructus: with blood vessels, the grain of living, removing pathogenic heat from blood and toxic substance from the body, pain relieving.It contains protein modern study, calcium phosphorus, ferrum, and various active organic substances such as vitamin have very strong permeability to skin.
Radix Paeoniae Rubra: sour, bitter, be slightly cold, return liver, spleen channel, removing blood stasis and activating blood flow, the eliminating pathogen in the liver heat clearing away is used for carbuncle, and blood closes.Modern study shows that it has antiinflammatory, antipathogen, the effect of enhancing immunity.
Flos Lonicerae: sweet, bitter, return, stomach, the heart, spleen channel heat-clearing and toxic substances removing, calentura, dysentery, cellulitis sore.It has antiinflammatory action modern study, enhance immunity mechanism.
Fructus Forsythiae: bitter, be slightly cold GUIXIN, lung, tri-jiao channel, heat-clearing and toxic substances removing eliminating stagnation.It has inhibitory action to pathogenic microorganism modern study, and antiinflammatory action is arranged.
Radix Arnebiae (Radix Lithospermi): sweet, salty, cold, GUIXIN envelope, Liver Channel, removing heat from blood and promoting blood circulation, detoxifcation lung moistening, prevention measles, macule variola, carbuncle, constipation due to dry stool.Modern study it have antiinflammatory to suppress the effect of pathogenic microorganism.
Radix Trichosanthis: little hardship, be slightly cold, return, lung, stomach warp, quench the thirst and move back dysphoria with smothery sensation, be used to quench one's thirst sore swollen toxin.It can improve immunity modern study, and antiinflammatory promotes the production of body fluid, detumescence and apocenosis.
Cortex Dictamni: go into spleen, stomach warp, heat clearing and damp drying, the detoxifcation of dispeling the wind is used for damp and hot sore, and yellow fluid is dripping, eczema, rheumatic fever, jaundice, dark coloured urine.Its root of modern study contains shaggy-fruited dittany alkali, dictamnolactone medicine, has antitumaous effect.
Herba Menthae: hot, cool, return Liver Channel, function of gallbladder promoting, diaphoresis are arranged, the wind heat effect of loosing is used to the conjunctival congestion of having a headache, pharyngalgia, macule is warded off dirty detoxifcation, the urticaria Pruritus.It has antivirus action modern study, and viral ECHLL strain is had inhibitory action, has analgesia, bactericidal action.
Rhizoma Et Radix Notopterygii: arduous temperature, Liver and kidney is delivered diffusing rheumatism, is used for Feng Shi Paralysis pain, anemofrigid cold, headache.
Fructus kochiae: sharp bladder, the usefulness of washing skin.It has inhibitory action to dermatophytes modern study, antiallergic.
Radix Et Rhizoma Rhei: bitter cold, return the Liver and kidney large intestine, the tangible thing of following the intestines and stomach rushes down the pathogenic heat in the blood, is used for what tachometer poison malignant boil.It has antiviral modern study, the antigen microorganism, and microcirculation improvement is invigorated blood circulation, and improves the immunity antiinflammatory, antitumor action.
Radix Glycyrrhizae: coordinating the actions of various ingredients in a prescription, detoxifcation, modern study it have antiinflammatory to protect the liver, and has antibiotic, anti-allergic effects.
Myrrha: bitter flat, conscience, the circulation of qi promoting eliminating stasis to stop pain is used for carbuncle, promoting blood circulation to remove blood stasis, acute appendicitis.Modern study its can anti-tinea bacterium.
Be the composition principle analysis of this medicament below,
The Radix Rehmanniae, Cortex Moutan, Cortex Lycii, Retinervus Luffae Fructus, Radix Paeoniae Rubra are monarch drug, main heat-clearing and toxic substances removing, promoting blood circulation and cooling blood, and the dissipating blood stasis dissipating rashes, and can remove the heat of hectic fever due to YIN-deficiency.
Radix Trichosanthis, Flos Lonicerae, Fructus Forsythiae, Herba Menthae, Radix Arnebiae (Radix Lithospermi) are ministerial drug, and effect is the effect that strengthens heat-clearing and toxic substances removing, and the energy dredge the meridian passage, microcirculation improvement.
Cortex Dictamni, fructus kochiae, Radix Tripterygii Wilfordii, Rhizoma Et Radix Notopterygii are adjuvant drug, remove the wind damp eliminating, skin moistening and itch stopping, speckle dispelling pain relieving.
Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Myrrha are the messenger drug loosening bowel to relieve constipation, concoct all medicines, promoting the circulation of QI to relieve pain.
The manufacture method of medicine of the present invention is as follows:
Getting above-mentioned selected medicine dries in the shade, by described proportion speed weighing, Retinervus Luffae Fructus cold water is wherein cleaned, put into marmite, add water purification to not having Fructus Luffae to be as the criterion, the decoction of setting fire was boiled after boiling 15 minutes again, take out medicinal liquid after, decoct one time by last method again, two liquid of boiling medicine are poured on together, in the bottle of packing into, or standby in the vacuum medicated bag.All the other medical materials grind to 120 order fine powders, put shady and cool dry place and further dry in the shade.Press every bag of 12g packing behind the mixing.
Product of the present invention can also be made decoction, takes for the patient with severe symptoms.
Be suitable for disease: by the psoriasis that heat in blood causes, lupus erythematosus, eczema ecchymosis, dermatosis such as purpura.
Using method: 1 bag of each one after each meal, drink Retinervus Luffae Fructus water 50g, 2 bags of adult every days, every bag of 12g, the child reduces by half.
The beneficial effect of medicine of the present invention is: compatibility of drugs science of the present invention, complete function, at first selected promoting blood circulation and cooling blood for use, the wet class medicine of the evanescence of heat of dispelling, intravital damp virus can be gathered in body surface, the reuse heat-clearing and toxic substances removing, stasis-resolving spot-removing class medicine is concentrated and is removed, and by skin moistening and itch stopping, dredge the meridian passage class medicine promotes the regeneration of healthy skin.According to the viewpoint of modern medicine, selected a lot of medicines all possess significant antiinflammatory, antibiotic, anti-infectious function, can effectively get rid of various viruses and pathogenic bacteria, and can suppress the invasion of pathogenic microorganism.At the microcirculation that has also improved body surface except that the evil toxicide while, make immunity of organisms obtain improving greatly, thereby can access a persistent curative effect.The big advantage of another of medicine of the present invention is that toxic and side effects is especially little, can not cause any harm to liver, kidney, lymphsystem.
Specific embodiment
Example 1
The raw material composition and the weight proportion of product of the present invention are as follows:
Radix Rehmanniae 30g Cortex Moutan 30g Cortex Lycii 30g
Radix Paeoniae Rubra 25g Radix Tripterygii Wilfordii 10g Radix Trichosanthis 20g
Flos Lonicerae 20g Fructus Forsythiae 20g Radix Arnebiae (Radix Lithospermi) 20g
Cortex Dictamni 20g Herba Menthae 20g Radix Et Rhizoma Rhei 15g
Radix Glycyrrhizae 15g fructus kochiae 15g Rhizoma Et Radix Notopterygii 15g
Myrrha 10g Retinervus Luffae Fructus 30g
Example 2
The Radix Rehmanniae, Cortex Moutan, Cortex Lycii, Retinervus Luffae Fructus, Radix Paeoniae Rubra
The raw material composition and the weight proportion of product of the present invention are as follows:
Radix Rehmanniae 25g Cortex Moutan 30g Cortex Lycii 25g
Radix Paeoniae Rubra 25g Radix Tripterygii Wilfordii 20g Radix Trichosanthis 15g
Flos Lonicerae 15g Fructus Forsythiae 15g Radix Arnebiae (Radix Lithospermi) 20g
Cortex Dictamni 15g Herba Menthae 10g Radix Et Rhizoma Rhei 15g
Radix Glycyrrhizae 10g fructus kochiae 15g Rhizoma Et Radix Notopterygii 10g
Myrrha 8g Retinervus Luffae Fructus 30g
Example 3
The raw material composition and the weight proportion of product of the present invention are as follows:
Radix Rehmanniae 25g Cortex Moutan 30g Cortex Lycii 20g
Radix Paeoniae Rubra 10g Radix Tripterygii Wilfordii 30g Radix Trichosanthis 10g
Flos Lonicerae 20g Fructus Forsythiae 20g Radix Arnebiae (Radix Lithospermi) 10g
Cortex Dictamni 20g Herba Menthae 15g Radix Et Rhizoma Rhei 10g
Radix Glycyrrhizae 15g fructus kochiae 15g Rhizoma Et Radix Notopterygii 10g
Myrrha 10g Retinervus Luffae Fructus 25g
Example 4
The model case of medicine of the present invention.
Chen Xiuyun, the woman, 50 years old, the patient shoveled ground down on the farm before 15 years, and after drenching with rain, second day, being dispersed in property erythema appearred in duplex and knee, and there is white scales on the surface, does not originally take notice of, after hospital is diagnosed as psoriasis, though through being interrupted treatment and not feeling any better.After go to Harbin again, cure on ground such as Shenyang does not still have improvement.Do birth control surgery in the time of 40 years old, because whole body Pruritus and be covered with erythra, so abandon performing the operation.Used Drug therapy of the present invention afterwards, according to inspection, the whole body erythema, and the ground figure is arranged, and breach is hemorrhage, and the pain of itching interweaves, desquamation, brothers' heating, wiry and frequent pulse is hard and dry, yellowish or reddish urine, being subjected to wet causes that menstruation is blue, and clot is arranged, heat in blood is sent out speckle, the skin pruritus due to dryness.With three courses of treatment of this side, be 15 days per course of treatment.The scurf attenuation has not had breach, three courses of treatment of continuous the place ahead, recovery from illness, the criminal of not having so far.
Example 4
The model case of medicine of the present invention
Xiao Xinhong: the man is 22 years old, unmarried.Patient spring puts sheep out to pasture going up a hill, and afterwards in the grave mound sleep, the aftersensation of getting up is uncomfortable from head to foot, and the 3rd day, pimple was played on the whole body, and with very itching, is psoriasis after Qiqihaer City first hospital examines.Well-planned failing to respond to any medical treatment in the period of several treated to me upon somebody's introduction.Inspection is removed outside the exposure skin, and the skin ulcer face spreads all over whole body, and good skin is few.Whole body skin ulcer face is restrained rapidly after medication two courses of treatment, becomes the generation of being dispersed in property, and xerosis cutis in 30 days is taken off the white scales redness and invaded profit, is almost recovered, and continuous clothes are completely recovered a course of treatment, do not see recurrence so far.
The comprehensive therapeutic effect analysis of medicine of the present invention:
With Drug therapy patient of the present invention name surplus in the of totally 148, wherein the psoriatic is 69 in nearly 1 year for the applicant, treat three courses of treatment after, the dermatosis wound person of being clearly better be effectively, it is produce effects that disease is created complete obiteration person.Total effective rate is 90.5%, and obvious effective rate is 79%.
Efficacy analysis
| Psoriasis | Lupus erythematosus | The eczema ecchymosis | Purpura | Dermatosis | Comprehensively | |
| Patient's number | 69 | 19 | 22 | 11 | 27 | 148 |
| Effective number | 64 | 16 | 20 | 9 | 25 | 134 |
| Effective percentage | 92.7％ | 84.2％ | 91％ | 81.8％ | 92.6％ | 90.5％ |
| The produce effects number | 58 | 11 | 18 | 7 | 23 | 117 |
| Obvious effective rate | 84％ | 57.9％ | 81.8％ | 63.6％ | 85.2％ | 79％ |
Claims (2)
1, the psoriatic Chinese medicine preparation of a kind of treatment is characterized in that: this Chinese medicine preparation adopts following raw material components and weight portion proportioning to be prepared from:
Radix Rehmanniae 15---30 part Cortex Moutan 15---30 part Cortex Lycii 15---30 part
Radix Paeoniae Rubra 10---25 part Radix Tripterygii Wilfordii 10---30 part Radix Trichosanthis 8---20 part
Flos Lonicerae 10---20 part Fructus Forsythiae 10---20 part Radix Arnebiae (Radix Lithospermi) 10---20 part
Cortex Dictamni 10---20 part Herba Menthae 10---20 part Radix Et Rhizoma Rhei 8---15 part
Radix Glycyrrhizae 8---15 part fructus kochiae 10---15 part Rhizoma Et Radix Notopterygii 10---15 part
Myrrha 3---10 part Retinervus Luffae Fructus 15---35 part.
2, the preparation method of psoriatic Chinese medicine preparation is treated in a kind of preparation according to claim 1, it is characterized in that: get above-mentioned selected medicine and dry in the shade, by described proportion speed weighing, Retinervus Luffae Fructus cold water is wherein cleaned, put into marmite, add water purification to not having Fructus Luffae to be as the criterion, the decoction of setting fire, boiled again after boiling 15 minutes, after taking out medicinal liquid, decoct one time by last method, two liquid of boiling medicine are poured on together again, pack in the bottle, or standby in the vacuum medicated bag; All the other medical materials grind to 120 order fine powders, put shady and cool dry place and further dry in the shade; Press every bag of 12g packing behind the mixing.
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| CN1235036A (en) * | 1998-05-11 | 1999-11-17 | 张祥新 | Chinese medicine and prescription for psoriasis |
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