CN101406511B - External-use medicament for treating vitiligo - Google Patents
External-use medicament for treating vitiligo Download PDFInfo
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- CN101406511B CN101406511B CN2008101604037A CN200810160403A CN101406511B CN 101406511 B CN101406511 B CN 101406511B CN 2008101604037 A CN2008101604037 A CN 2008101604037A CN 200810160403 A CN200810160403 A CN 200810160403A CN 101406511 B CN101406511 B CN 101406511B
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- vitiligo
- healed
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- 239000003814 drug Substances 0.000 title claims abstract description 30
- 206010047642 Vitiligo Diseases 0.000 title abstract description 9
- 210000000582 semen Anatomy 0.000 claims abstract description 15
- 241001161070 Calomela Species 0.000 claims description 7
- 239000002994 raw material Substances 0.000 claims 2
- MUKYLHIZBOASDM-UHFFFAOYSA-N 2-[carbamimidoyl(methyl)amino]acetic acid 2,3,4,5,6-pentahydroxyhexanoic acid Chemical compound NC(=N)N(C)CC(O)=O.OCC(O)C(O)C(O)C(O)C(O)=O MUKYLHIZBOASDM-UHFFFAOYSA-N 0.000 abstract 1
- 244000241463 Cullen corylifolium Species 0.000 abstract 1
- 241000558306 Gynocardia odorata Species 0.000 abstract 1
- 241000132171 Phryma leptostachya Species 0.000 abstract 1
- 241000159213 Zygophyllaceae Species 0.000 abstract 1
- ZOMNIUBKTOKEHS-UHFFFAOYSA-L dimercury dichloride Chemical compound Cl[Hg][Hg]Cl ZOMNIUBKTOKEHS-UHFFFAOYSA-L 0.000 abstract 1
- HTUMBQDCCIXGCV-UHFFFAOYSA-N lead oxide Chemical compound [O-2].[Pb+2] HTUMBQDCCIXGCV-UHFFFAOYSA-N 0.000 abstract 1
- YEXPOXQUZXUXJW-UHFFFAOYSA-N lead(II) oxide Inorganic materials [Pb]=O YEXPOXQUZXUXJW-UHFFFAOYSA-N 0.000 abstract 1
- 235000009165 saligot Nutrition 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 244000045947 parasite Species 0.000 description 6
- 239000008280 blood Substances 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 3
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 241000209094 Oryza Species 0.000 description 2
- 235000007164 Oryza sativa Nutrition 0.000 description 2
- 230000003266 anti-allergic effect Effects 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 235000019504 cigarettes Nutrition 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 231100000344 non-irritating Toxicity 0.000 description 2
- 235000011837 pasties Nutrition 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 239000000049 pigment Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 208000037920 primary disease Diseases 0.000 description 2
- ZCCUUQDIBDJBTK-UHFFFAOYSA-N psoralen Chemical compound C1=C2OC(=O)C=CC2=CC2=C1OC=C2 ZCCUUQDIBDJBTK-UHFFFAOYSA-N 0.000 description 2
- 235000009566 rice Nutrition 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 206010040882 skin lesion Diseases 0.000 description 2
- 231100000444 skin lesion Toxicity 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 235000021419 vinegar Nutrition 0.000 description 2
- 239000000052 vinegar Substances 0.000 description 2
- VXGRJERITKFWPL-UHFFFAOYSA-N 4',5'-Dihydropsoralen Natural products C1=C2OC(=O)C=CC2=CC2=C1OCC2 VXGRJERITKFWPL-UHFFFAOYSA-N 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000201295 Euphrasia Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241001446509 Psoralea Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000000629 anti-dermatophyte Effects 0.000 description 1
- 230000001716 anti-fugal effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 238000011443 conventional therapy Methods 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- HAWPXGHAZFHHAD-UHFFFAOYSA-N mechlorethamine Chemical compound ClCCN(C)CCCl HAWPXGHAZFHHAD-UHFFFAOYSA-N 0.000 description 1
- 229960004961 mechlorethamine Drugs 0.000 description 1
- 208000017983 photosensitivity disease Diseases 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses an external applied medicine for treating vitiligo. The formula for the medicine is prepared by the following medicine formula in portion by weight: 20 portions of malaytea scurfpea, 18 portions of semen astragali complanati caltrop, 18 portions of chaulmoogra, 18 portions of litharge, 10 portions of mercurous chloride, 18 portions of fructus cnidii and 6 portions of lopseed. The external applied medicine has the advantages that vitiligo is difficult to relapse after being healed, and the external applied medicine has no stimulant function; slight patients can be healed after 1 to 2 treatment periods, and heavy patients can be healed after 3 to 5 treatment periods; and the effective rate is 76 percent, and the cure rate is 62 percent.
Description
Technical field
The invention belongs to pure technical field of Chinese medicines, the leukodermic external used medicine of specifically a kind of treatment.
Background technology
Vitiligo has another name called vitiligo, and how evil objective in skin by rheumatism, consequently qi-blood disharmony, blood does not allow skin to form.The primary disease skin lesion appearing without definite location, for circumscribed skin pigment takes off mistake, but the white patch single-shot that skin clear-cut margin occurs, differs in size also can general, and hair bleaches in the speckle, smooth surface is superficial, sensation is normal, and its infringement can be at any position, but based on the exposure portion morbidity, the course of disease is slow, and utmost point refractory more.Doctor trained in Western medicine is used hormone medicine, chlormethine alcohol treatment more, and effect is undesirable, and cure rate is low, and zest is arranged, easily recurrence.The traditional Chinese medical science is then with psoralea tincture, vitiligo sheet treatment (wound science) Guangdong college of traditional Chinese medicine.Though certain curative effect is all arranged, its effect is all undesirable, and effective percentage is low, easily recurrence.
The invention reside in provides a kind of effective percentage height, cures the back and is difficult for recurrence, the leukodermic external used medicine of non-irritating a kind of treatment.
Summary of the invention
Theory of Chinese medical science thinks that vitiligo is how evil objective in skin by rheumatism, and consequently qi-blood disharmony, blood does not allow skin to form.The primary disease skin lesion appearing without definite location, for circumscribed skin pigment takes off mistake, but the white patch single-shot that skin clear-cut margin occurs, differs in size also can general, and hair bleaches in the speckle, smooth surface is superficial, sensation is normal, and its infringement can be at any position, but based on the exposure portion morbidity, the course of disease is slow, and utmost point refractory more.
The object of the invention provides a kind of effective percentage height, is difficult for recurrence, the leukodermic external used medicine of non-irritating a kind of treatment, Drug therapy vitiligo effective percentage 76% of the present invention, cure rate 62%.
Technical scheme of the present invention is achieved in that
Medicine of the present invention, the leukodermic external used medicine of a kind of treatment is characterized in that: it is made by following drugs and weight portion proportioning: Fructus Psoraleae 10-20, Semen Astragali Complanati 10-18, Semen Hydnocarpi 12-20, Lithargyrum 10-18, Calomelas 6-12, Fructus Cnidii 10-20, Herba speranskiae tuberculatae 6-9.
Medicine of the present invention, the leukodermic external used medicine of a kind of treatment is characterized in that: it is made by following drugs and weight portion proportioning: Fructus Psoraleae 20, Semen Astragali Complanati 18, Semen Hydnocarpi 18, Lithargyrum 18, Calomelas 10, Fructus Cnidii 18, Herba speranskiae tuberculatae 6.
Drug action mechanism of the present invention is as follows:
Fructus Psoraleae kidney invigorating and YANG supporting, modern pharmacological research have anti-photosensitization, and psoralen can promote the synthetic of dermal melanin, and makes it to be deposited on subcutaneous; Semen Astragali Complanati suppressing the hyperactive liver vegetables liver, Eradicates wind make eye bright, and modern pharmacological research has immunity and anti-allergic effects, and dermatosis is had therapeutical effect preferably; Semen Hydnocarpi detoxicating and killing parasites, Eradicates wind-dryness are wet; Lithargyrum's removing dampness and killing parasites, detoxifcation, convergence, anticorrosion have the anti-dermatophyte effect; The Calomelas counteracting toxic substances, parasite killing; The Fructus Cnidii killing parasites for relieving itching, the Eradicates wind-dryness is wet, and warming the kidney to activate YANG has antifungic action; The Herba speranskiae tuberculatae expelling wind and removing dampness, promoting blood circulation and stopping pain.
The present invention's Fructus Psoraleae, Semen Astragali Complanati Eradicates wind, the anti-allergic effects of enhancing skin; Detoxicating and killing parasites is wet in Lithargyrum, Calomelas, Semen Hydnocarpi, Fructus Cnidii Eradicates wind-dryness; The Herba speranskiae tuberculatae priming is gone into skin, and all medicines are harmonious, mutually easily clear, it is wet to have a Eradicates wind-dryness, the merit of detoxicating and killing parasites reaches the effect of rapid healing vitiligo.The processing of will adding medicine to cooks makes super cell grade (more than 300 orders) micropowder altogether, and it is standby to receive bottle.
1, using method: according to skin affected part size, get an amount of medicated powder,, smear, smear 0.5-3 millimeters thick, changed a time medicine in per 2 days in the affected part with rice vinegar furnishing pasty state.
2, use the course of treatment: 3-15 days is a course of treatment, the lighter, and can cure 1-2 courses of treatment; Weight person, can cure 3-5 courses of treatment.
3, therapeutic effect: advantage of the present invention is to cure the back to be difficult for recurrence, has no stimulation.The lighter can cure 1-2 courses of treatment; Weight person, can cure 3-5 courses of treatment, effective percentage 76%, cure rate 62%.
4, taboo: hot, peppery, wine, cigarette.
The specific embodiment:
Embodiment: get Fructus Psoraleae 20, Semen Astragali Complanati 18, Semen Hydnocarpi 18, Lithargyrum 18, Calomelas 10, Fructus Cnidii 18, Herba speranskiae tuberculatae 6.The processing of will adding medicine to cooks makes super cell grade (more than 300 orders) micropowder altogether, and it is standby to receive bottle.
1, using method: according to skin affected part size, get an amount of medicated powder,, smear, smear 0.5-3 millimeters thick, changed a time medicine in per 2 days in the affected part with rice vinegar furnishing pasty state.
2, use the course of treatment: 3-15 days is a course of treatment, the lighter, and can cure 1-2 courses of treatment; Weight person, can cure 3-5 courses of treatment.
3, therapeutic effect: advantage of the present invention is to cure the back to be difficult for recurrence, has no stimulation.The lighter can cure 1-2 courses of treatment; Weight person, can cure 3-5 courses of treatment, effective percentage 76%, cure rate 62%.
4, taboo: hot, peppery, wine, cigarette.
For showing the curative effect of medicine of the present invention, the 100 routine patients that treat are divided into test group and matched group, test group has Drug therapy of the present invention, and the matched group conventional therapy all is effectively with the sx, is recovery from illness with the transference cure.
Test group is treated 50 examples, effective percentage 76%, cure rate 62%.
Treatment of control group 50 examples, effective percentage 16%, cure rate 10%.
Claims (2)
1. treat leukodermic external used medicine for one kind, it is characterized in that it is made by following raw material medicaments and weight portion proportioning: Fructus Psoraleae 10-20, Semen Astragali Complanati 10-18, Semen Hydnocarpi 12-20, Lithargyrum 10-18, Calomelas 6-12, Fructus Cnidii 10-20, Herba speranskiae tuberculatae 6-9.
2. the leukodermic external used medicine of a kind of treatment according to claim 1, it is characterized in that it is made by following raw material medicaments and weight portion proportioning: Fructus Psoraleae 20, Semen Astragali Complanati 18, Semen Hydnocarpi 18, Lithargyrum 18, Calomelas 10, Fructus Cnidii 18, Herba speranskiae tuberculatae 6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101604037A CN101406511B (en) | 2008-11-18 | 2008-11-18 | External-use medicament for treating vitiligo |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101604037A CN101406511B (en) | 2008-11-18 | 2008-11-18 | External-use medicament for treating vitiligo |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101406511A CN101406511A (en) | 2009-04-15 |
| CN101406511B true CN101406511B (en) | 2010-11-17 |
Family
ID=40569856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008101604037A Expired - Fee Related CN101406511B (en) | 2008-11-18 | 2008-11-18 | External-use medicament for treating vitiligo |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101406511B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2973697B1 (en) * | 2011-04-05 | 2013-10-25 | Nuxe Lab | COMPOSITION BASED ON OIL OF CHAULMOOGRA AND TRIBULUS TERRESTRIS FOR THE PIGMENTATION OF THE SKIN. |
| CN102908492B (en) * | 2012-10-24 | 2014-02-12 | 尹甲仑 | Traditional Chinese medicine composition for treating vitiligo and preparation method of traditional Chinese medicine composition |
| CN105833150A (en) * | 2016-05-17 | 2016-08-10 | 商皓 | Externally-applied medicine for treating leucoderma |
-
2008
- 2008-11-18 CN CN2008101604037A patent/CN101406511B/en not_active Expired - Fee Related
Non-Patent Citations (4)
| Title |
|---|
| 梁小梅.中药补骨脂为要药治疗白癜风40例.《中华全科医师杂质》.2003,第2卷(第4期), |
| 梁小梅.中药补骨脂为要药治疗白癜风40例.《中华全科医师杂质》.2003,第2卷(第4期). * |
| 陈梅花等.中药外用治疗白癜风的临床应用概况.《中国中西医结合皮肤性病学杂质》.2005,第4卷(第4期), |
| 陈梅花等.中药外用治疗白癜风的临床应用概况.《中国中西医结合皮肤性病学杂质》.2005,第4卷(第4期). * |
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| Publication number | Publication date |
|---|---|
| CN101406511A (en) | 2009-04-15 |
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Granted publication date: 20101117 Termination date: 20111118 |