CN101352169B - Pesticide composition based on ivermectin - Google Patents
Pesticide composition based on ivermectin Download PDFInfo
- Publication number
- CN101352169B CN101352169B CN2008102119630A CN200810211963A CN101352169B CN 101352169 B CN101352169 B CN 101352169B CN 2008102119630 A CN2008102119630 A CN 2008102119630A CN 200810211963 A CN200810211963 A CN 200810211963A CN 101352169 B CN101352169 B CN 101352169B
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- Prior art keywords
- ivermectin
- insect
- mixed
- pesticide
- sodium
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- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
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- 239000001023 inorganic pigment Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 229940126181 ion channel inhibitor Drugs 0.000 description 1
- DCYOBGZUOMKFPA-UHFFFAOYSA-N iron(2+);iron(3+);octadecacyanide Chemical compound [Fe+2].[Fe+2].[Fe+2].[Fe+3].[Fe+3].[Fe+3].[Fe+3].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] DCYOBGZUOMKFPA-UHFFFAOYSA-N 0.000 description 1
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- QPJVMBTYPHYUOC-UHFFFAOYSA-N methyl benzoate Chemical class COC(=O)C1=CC=CC=C1 QPJVMBTYPHYUOC-UHFFFAOYSA-N 0.000 description 1
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- 238000002156 mixing Methods 0.000 description 1
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- 229960003512 nicotinic acid Drugs 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
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- 239000003960 organic solvent Substances 0.000 description 1
- 239000003992 organochlorine insecticide Substances 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- IEQIEDJGQAUEQZ-UHFFFAOYSA-N phthalocyanine Chemical compound N1C(N=C2C3=CC=CC=C3C(N=C3C4=CC=CC=C4C(=N4)N3)=N2)=C(C=CC=C2)C2=C1N=C1C2=CC=CC=C2C4=N1 IEQIEDJGQAUEQZ-UHFFFAOYSA-N 0.000 description 1
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- 229920006324 polyoxymethylene Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
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- 244000144977 poultry Species 0.000 description 1
- 229940088417 precipitated calcium carbonate Drugs 0.000 description 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 description 1
- 229960003351 prussian blue Drugs 0.000 description 1
- 239000013225 prussian blue Substances 0.000 description 1
- 239000002728 pyrethroid Substances 0.000 description 1
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- 235000009566 rice Nutrition 0.000 description 1
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- 150000007949 saponins Chemical class 0.000 description 1
- 229910052624 sepiolite Inorganic materials 0.000 description 1
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- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
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- 229910052911 sodium silicate Inorganic materials 0.000 description 1
- JAJWGJBVLPIOOH-IZYKLYLVSA-M sodium taurocholate Chemical compound [Na+].C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS([O-])(=O)=O)C)[C@@]2(C)[C@@H](O)C1 JAJWGJBVLPIOOH-IZYKLYLVSA-M 0.000 description 1
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- 239000010457 zeolite Substances 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to an agricultural chemical composition, more particularly relates to an agricultural chemical composition that comprises ivermectin (effective synergy component) and an insecticidal active constituent which is selected from indoxacarb, thiamethoxam and pymetrozine. The optimized weight proportion of ivermectin and indoxacarb is 2:1-1:20, and further optimized proportion is 1:1-1:15; the optimized weight proportion of ivermectin and thiamethoxam is 1:1-1:50, and further optimized proportion is 1:5-1:50; the optimized weight proportion of ivermectin and pymetrozine is 1:1-1:50, and further optimized proportion is 1:10-1:50.
Description
Technical field
The present invention relates to a kind of synergetic pesticide composition, particularly relate to a kind of synergetic pesticide composition that comprises ivermectin and be selected from arbitrary active insecticidal components of indenes worm prestige, thiophene worm piperazine and pyrrole aphid ketone.
Background technology
Ivermectin (Ivermectin) is to be lead compound with the Avermectin, by two key hydrogenations, and structure optimization and the novel synthetic pesticide succeeded in developing.Structure optimization product as agricultural antibiotic, compare with the parent Avermectin, its expelling parasite and acaricidal activity have not only been kept, and safety is higher, be difficult for to produce resistance, for the production of vegetables, fruit, cotton etc. provide efficient a, high security and with the good biogenic pesticide insecticide of Environmental compatibility.Ivermectin has stomach toxicity and action of contace poison to mite class and insect, and the horizontal infiltration conduction is arranged.Also can be used as additive and get antiparasitic agent.Nematode, insect and mite are all killed effect, be used for the treatment of intestines and stomach nematodosis, acariasis and the parasitic insect disease of fowl poultry.
Indenes worm prestige (indoxacarb), belong to Yi Zhong oxadiazine insecticides, it is insect sodium-ion channel inhibitor, it is mainly to tag and stomach poison function, there is not cross resistance in other insecticides, and to natural enemy insect safety, can be used for the insect comprehensive regulation (IPM) and resistance management (RPM), be used to that crops such as vegetables, cotton, beet prevent and treat various insects such as beet armyworm, tomato moth, diamond-back moth, imported cabbageworm, cotton bollworm, pink bollworm, cotten aphid, rice stinkbug, fruit eats into moth, potato leaf is first-class, and each instar larvae is all had good control efficiency.
Thiophene worm piperazine (thiamethoxam) is the anabasine insecticide of a kind of efficient, low toxicity, wide spectrum, its mechanism of action mainly is that selectivity suppresses insect central nervous system nicotinic acid acetylcholinesterase acceptor, and then the normal conduction of blocking-up insect central nervous system, death when causing insect the paralysis machine to occur.Thiophene worm piperazine not only have tag, stomach toxicity and systemic activity, and have better safety, wider insecticidal spectrum and characteristics such as speed of action is fast, the lasting period is long, be to replace those better kinds to mammalian toxicity height, the organic phosphates that residual and environmental problem are arranged, carbamates and organochlorine insecticides.Thiophene worm piperazine is to coleoptera, diptera, Lepidoptera, especially homoptera pest has high activity, can effectively prevent and treat insect such as various aphids, leafhopper, plant hopper, aleyrodid, chafer larva, colorado potato beetle, nematode, ground beetle, leaf miner and polytype produce resistance to chemical pesticide insect.Thiophene worm piperazine both can be used for cauline leaf, seed treatment, also can be used for soil treatment.
Pyrrole aphid ketone (pymetrozine), chemical name: (E)-4,5-dihydro-6-methyl-4-(3-pyridine methylene amino)-1,2,4-triazine-3 (2H)-ketone, be a kind of insecticidal/acaricidal agent that is specifically designed to control sucking pest such as aphid, trialeurodes vaporariorum, rice leafhopper, small brown rice planthopper etc., be widely used in crops, vegetables, ornamental plants, cotton, hop, fruit tree, citrus and paddy rice etc. both at home and abroad.This insecticidal/acaricidal agent has selectivity highly to insect, to people, mammal low toxicity, to birds, fish, non-target arthropods safety.Pyrrole aphid ketone has unique mode of action to insect, and it is different with conventional insecticidal/acaricidal agent, and to be the insect that stops sucking mouth parts on physiology insert plant tissue with lancet makes it hungry and death is good to rice fulgorid quick-acting.
The inventor studies have shown that by a series of ivermectin is mixed with the arbitrary active insecticidal components that is selected from indenes worm prestige, thiophene worm piperazine and pyrrole aphid ketone target pest is had extremely strong synergistic effect, thereby has finished the present invention.
Summary of the invention
The object of the present invention is to provide a kind of mixed ratio reasonable, control efficiency is good, the synergetic pesticide composition that drug cost is low.
Another object of the present invention is to provide by formulations such as the formulated missible oil of this composition pesticide, wetting powder, microemulsion, aqueous emulsion, suspending agent or water dispersible granules.
Technical scheme of the present invention is as described below:
A kind of composition pesticide, the arbitrary active insecticidal components that it is characterized in that containing the ivermectin of synergy effective dose and be selected from indenes worm prestige, thiophene worm piperazine and pyrrole aphid ketone.
Wherein, the weight ratio of ivermectin and indenes worm prestige is preferably 2:1～1:20, more preferably 1:1～1:15; The weight ratio of ivermectin and thiophene worm piperazine is preferably 1:1～1:50, more preferably 1:5～1:50; The weight ratio of ivermectin and pyrrole aphid ketone is preferably 1:1～1:50, more preferably 1:10～1:50.
Composition pesticide of the present invention can be mixed with formulations such as missible oil, wetting powder, microemulsion, aqueous emulsion, suspending agent or water dispersible granules according to the method for well known to a person skilled in the art.
Except active component, the also optional functional aid that comprises in the composition pesticide of the present invention.That is to say, composition pesticide of the present invention also can add other components such as functional aid, is mixed with missible oil, wetting powder, microemulsion, aqueous emulsion, suspending agent, water dispersible granules or other formulations with the routine techniques means according to those skilled in the art.
In above-mentioned formulation, except that active component, usually all can contain surfactant, and also can choose wantonly according to different dosage form and to contain organic solvent (or cosolvent), carrier (or filler) and water etc., also can add other auxiliary agents such as antifreeze, thickener, stabilizing agent, defoamer, disintegrant in case of necessity.Surfactant can be emulsifier, dispersant, wetting agent or the bleeding agent of nonionic or ionic, also can be the compound use of two or more surfactants.
Described emulsifier can be alkylphenol-polyethenoxy (polyoxypropylene) ether, benzylphenol APEO, phenethyl phenol polyethenoxy ether, fatty alcohol-polyoxyethylene ether, polyoxyethylene carboxylate, phenethyl phenol polyethenoxy polyethenoxy ether, castor oil ethylene oxide adduct, alkylphenol polyoxyethylene formaldehyde condensation products, and the phosphate of these compounds, alkyl benzene sulphonate (calcium salt or sodium salt) or directly use commercially available emulsifier monomer and composite product.The newborn 500# series of concrete example such as farming, 600# series, 1600# series, NP series, OP series, AEO series, 700#, 400# series and composite kind 2201 thereof, 0203B, 2021B, 4103 etc., these all are emulsifier productions well known in the art, and market is on sale.
Described dispersant; wetting agent; bleeding agent can be lignosulfonates (sodium salt or calcium salts); Negel; condensation compound of methyl naphthalene sulfonic acid and formaldehyde sulphate; naphthalene sulfonic acid-formaldehyde condensation product; methanonaphthalene sodium sulfonate dibutyl naphthalene sulfonic acid-formaldehyde condensation product; N-methyl fatty acyl group sodium taurocholate; alkylphenol polyoxyethylene formaldehyde condensation products sulphate; polymerization of carboxylic acid sodium; the alkylphenol polyoxyethylene phosphate; the withered powder of tea; saponin; lignosulfite; aliphatic alcohol sulfate; dodecyl sodium sulfate; alkylbenzenesulfonate; penetrant t; bleeding agent OT; fatty acid amide-N methyl taurine sodium salt; sodium sulfate of polyethenoxy ether of fatty alcohol; draw back powder or JFC etc.They can use separately, also can compoundly use.Above-mentioned surfactant all is materials well known in the art, can obtain by various commercial channel.
Described solvent, cosolvent can be toluene, dimethylbenzene, chlorobenzene, solvent naphtha, alpha-methyl-naphthalene, turpentine oil, carrene, chloroform, methyl alcohol, ethanol, isopropyl alcohol, butanols, isoamyl alcohol, cyclohexanone, isophorone, acetophenone, ethyl acetate, butyl acetate, N.N-dimethyl formamide, dimethyl sulfoxide (DMSO), methyl cellosolve or ethyl cellosolve etc.
Described antifreeze can be ethylene glycol, glycerine, propane diols, urea, glycerine, ether diglycol, polyethylene glycol or isopropyl alcohol etc.
Described carrier, filler can be white carbon, precipitated calcium carbonate, potter's clay, attapulgite, kaolin, diatomite, bentonite, sepiolite, zeolite, quartz sand or talcum powder etc.They can use separately, also can two kinds or above mixing use.
Described disintegrant can be sodium alginate, sodium carboxymethyl starch, sulfuric acid amine, bentonite, urea or calcium chloride etc.
Described defoamer has bubble enemy, silicone, C
8-10Fatty alcohol, C
10-20Saturated fat acids (as capric acid, stearic acid etc.) and amide-type etc.
Described binding agent has starch, dextrin, gum Arabic, soybean protein, gelatine, sodium sulphate, gypsum, polyvinyl alcohol, polyethylene glycol, rosin, paraffin, CMC or sodium silicate etc.They can use separately, also can two or morely use with.
Can contain toner in the preparation, inorganic pigment iron oxide for example, titanium oxide or Prussian blue; Organic dyestuff is as A Lizhalin, azo dyes, metal phthalocyanine or kiton colors.In water-base preparation, for preventing moldy metamorphism, can choose wantonly and add a certain amount of preservative, described preservative has Sodium Benzoate, polyformaldehyde, sorbitol, formalin, citric acid, to yl benzoic acid methyl esters, O-SyL sodium, 1,2-benzisothiazole-3-ketone etc.
The composition that the present invention has a pesticide and miticide actility can be used for preventing and treating the thorny insect on the important agricultural crops such as cotton, fruit tree, vegetables, tea tree, gardening, eats into moth, lyonetid, tea geometrid, fleahopper, leafhopper, thrips, aphid, chrysomelid, aleyrodid, various tetranychids etc. as cotton bollworm, pink bollworm, corn borer, beet armyworm, prodenia litura, tomato moth, imported cabbageworm, leaf roller, fruit.
Though having the amount of application of the composition of pesticide and miticide actility, the present invention need adjust according to the kind of essential condition such as population density, core crop and cropping pattern, weather condition, method of application etc., but generally speaking, the total amount of the composition with pesticide and miticide actility that per hectare is used is 0.1～1000g, is 10～100g. preferably.In practice, the composition that has pesticide and miticide actility as the present invention is wetting powder, missible oil, microemulsion, colloidal suspending agent, water-dispersible granules etc., can impose on the crop after the consumption dilution by correspondence.
Component of the present invention is reasonable, and drug cost is low, good disinsection effect, and its insecticidal effect and activity level are not the stacks of simple each composition activity, but the effect of synergy is arranged.
Embodiment
The invention will be further described below in conjunction with embodiment.But the present invention only limits to these examples absolutely not.Umber or proportioning are parts by weight or weight ratio in all prescriptions.To be the public known for the processing technology of various preparations and equipment in the present composition.
Example of formulations 1
2 parts of ivermectins
1 part of indenes worm prestige
5 parts of the newborn 500# of farming
5 parts of the newborn 601# of farming
Dimethylbenzene complements to 100 parts
With mentioned component homogeneous mixture and dissolving, obtain missible oil.This preparation possibility is prevented and treated insects such as vegetables cabbage caterpillar, beet armyworm, prodenia litura effectively.
Example of formulations 2
2 parts of ivermectins
0.5 part of thiophene worm piperazine
15 parts of the newborn 500# of farming
N, 5 parts of dinethylformamides
Dimethylbenzene complements to 100 parts
Mentioned component is mixed equably and dissolve, obtain missible oil.This preparation possibility is prevented and treated pests such as lepidoptera pest, all kinds of aphid, mite effectively.
Example of formulations 3
1 part of ivermectin
10 parts of pyrrole aphid ketone
20 parts of Tween 80s
5 parts of cyclohexanes
Dimethylbenzene complements to 100 parts
With mentioned component homogeneous mixture and dissolving, obtain missible oil.This preparation possibility is prevented and treated pests such as lepidoptera pest, all kinds of aphid, mite effectively.
Example of formulations 4
1 part of ivermectin
1 part of pyrrole aphid ketone
20 parts of sldium lauryl sulfates
15 parts of calcium lignosulfonates
Kaolin complements to 100 parts
With the airbrasive machine mentioned component is mixed equably, get wetting powder.Pests such as this preparation possibility control lepidoptera pest, all kinds of aphid, mite.
Biological Examples 1: ivermectin and indenes worm prestige are mixed to the toxicity test of cabbage caterpillar
With resistance cabbage caterpillar (Pieris rapae) 3 instar larvaes is tested object.This confession examination cabbage caterpillar is picked up from Fujian China Foochow vegetable field, and it has reached high anti-level to the resistance of pyrethroid and organophosphorus insecticides.
The leaf dipping method that adopts international resistance Action Committee (IRAC) to carry.The Mixed Pharmacy of reagent agent and different proportion thereof is diluted to 5 series concentration with running water, cabbage leaves is cut into the fritter of 6～7cm, immerse the about 5S of soup and take out, after indoor drying, again blade is put into and be connected to the culture dish that tries worm, preserve moisture with wet cotton balls.Compare with clear water, each is handled 3 times and repeats, and each repeats 1 culture dish, and each culture dish is put and tried worm 20 three ages.24h, 48h, each handling dead of 72h observed and recorded, the borer population of living behind the medicine.Larva death standard: touch examination worm polypide with the writing brush point, do not have obvious autonomic response person and be judged as death.Calculate the corrected mortality that each is handled with the Abbott formula, with the lethal concentration of 50 (LC of 72h after the computing of DPS software
50), correlation coefficient and regression equation.According to the insecticide synergy virulence computational methods of reports such as Sun Yunpei, calculate co-toxicity coefficient (CTC).The symphyogenetic evaluation method of mixture is to adopt the abundant method of Sun Yun, promptly calculates the co-toxicity coefficient (CTC) of each proportioning combination, estimates the interaction property of mixture by comparing co-toxicity coefficient.The result is as shown in table 1:
Table 1: ivermectin and indenes worm prestige are mixed to the toxicity test result of cabbage caterpillar
She: indenes=ivermectin: indenes worm prestige
Biological Examples 2: thiophene worm piperazine and ivermectin are mixed to the toxicity test of trialeurodes vaporariorum
On the basis of preliminary experiment, behind former medicinal proper amount of acetone preliminarily solubilised, and be mixed into the mother liquor of different proportionings in set ratio.Each mother liquor is mixed with 5 serial test solutions with distilled water, and concentration range can cause that supplying to try insect mortality reaches 10%～90%, puts in the beaker stand-by.The spray-on process of recommending with reference to FAO is carried out Toxicity Determination then.Gather trialeurodes vaporariorum from the field and take back indoorly, blade is put into the glass culture dish of the wet filter paper of pad together with trialeurodes vaporariorum, under spray tower with the processing of spraying of certain soup.Every processing weighs 3 times, handles in contrast with clear water, places in the greenhouse of (25 ± 1) ℃.Handle back 48h and check death toll, calculate lethality,, calculate LC50 and virulence regression equation with DPS software with each lethality of handling of Abbott formula correction.Adopt Sun Pei cloud method to obtain the co-toxicity coefficient (CTC) of each mixed ratio with reference to NY/T1154.7-2006, and estimate the synergistic effect that the two is used with.The result is as shown in table 2:
Table 2: ivermectin and pyrrole aphid ketone are mixed to the toxicity test result of trialeurodes vaporariorum
She: pyrrole=ivermectin: pyrrole aphid ketone
Biological Examples 3: thiophene worm a kind of cicada mentioned in ancient books and ivermectin are mixed to the toxicity test of vegetables thrips
On the basis of preliminary experiment, behind former medicinal proper amount of acetone preliminarily solubilised, and be mixed into the mother liquor of different proportionings in set ratio.Each mother liquor is mixed with 5 serial test solutions with distilled water, and concentration range can cause that supplying to try insect mortality reaches 10%～90%, puts in the beaker stand-by.The spray-on process of recommending with reference to FAO is carried out Toxicity Determination then.Gather thrips at vegetable field and take back indoorly, blade is put into the glass culture dish of the wet filter paper of pad together with thrips, under spray tower with the processing of spraying of certain soup.Every processing weighs 3 times, handles in contrast with clear water, places in the greenhouse of (25 ± 1) ℃.Handle back 48h and check death toll, calculate lethality,, calculate LC50 and virulence regression equation with DPS software with each lethality of handling of Abbott formula correction.Adopt Sun Pei cloud method to obtain the co-toxicity coefficient (CTC) of each mixed ratio with reference to NY/T1154.7-2006, and estimate the synergistic effect that the two is used with.The result is as shown in table 3:
Table 3: thiophene worm a kind of cicada mentioned in ancient books and ivermectin are mixed to the toxicity test result of vegetables thrips
She: thiophene=ivermectin: thiophene worm piperazine
Claims (3)
1. composition pesticide is characterized in that containing ivermectin and indenes worm prestige, and the weight ratio of ivermectin and indenes worm prestige is 2: 1～1: 20.
2. composition pesticide according to claim 1 is characterized in that the weight ratio of ivermectin and indenes worm prestige is 1: 1～1: 15.
3. composition pesticide according to claim 1 and 2 is characterized in that this composition pesticide is missible oil, wetting powder, microemulsion, aqueous emulsion, suspending agent or water dispersible granules.
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| CN2008102119630A CN101352169B (en) | 2008-09-12 | 2008-09-12 | Pesticide composition based on ivermectin |
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| CN2008102119630A CN101352169B (en) | 2008-09-12 | 2008-09-12 | Pesticide composition based on ivermectin |
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| Publication Number | Publication Date |
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| CN101352169A CN101352169A (en) | 2009-01-28 |
| CN101352169B true CN101352169B (en) | 2011-04-20 |
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| CN2008102119630A Expired - Fee Related CN101352169B (en) | 2008-09-12 | 2008-09-12 | Pesticide composition based on ivermectin |
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Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101766176B (en) * | 2010-01-26 | 2013-09-04 | 中国水稻研究所 | Pymetrozine and ivermectin mixed pesticide |
| CN101810187B (en) * | 2010-04-01 | 2014-06-18 | 上海悦联化工有限公司 | Pesticide combination containing thiamethoxam and pymetrozine |
| CN102763672B (en) * | 2012-08-13 | 2014-01-08 | 广西汇丰生物科技有限公司 | Granula containing ivermectin and clothianidin |
| CN103070197A (en) * | 2012-12-29 | 2013-05-01 | 广东中迅农科股份有限公司 | Insecticidal composition of indoxacarb and agritol |
| CN105340940A (en) * | 2015-12-14 | 2016-02-24 | 济南舜昊生物科技有限公司 | Insecticide composition containing benclothiaz and indoxacarb |
| CN105941445B (en) * | 2016-06-21 | 2018-09-07 | 南京华洲药业有限公司 | A kind of compound pesticide compositions and application thereof containing Lepimectin and d ichlorbenzuron |
| CN105941449A (en) * | 2016-06-21 | 2016-09-21 | 南京华洲药业有限公司 | Compound insecticidal composition containing Lepimectin and indoxacarb and application thereof |
| CN107242245A (en) * | 2017-07-15 | 2017-10-13 | 广西南宁益土生物科技有限责任公司 | A kind of Pesticidal combination containing Ivermectin HCL and indoxacarb |
| CN115227645A (en) * | 2022-08-03 | 2022-10-25 | 上虞颖泰精细化工有限公司 | Antiparasitic solution preparation containing ivermectin and neonicotinoid insecticides and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1925749A (en) * | 2004-03-16 | 2007-03-07 | 辛根塔参与股份公司 | Pesticidal composition and method for seed treatment |
| CN101027991A (en) * | 2007-04-04 | 2007-09-05 | 南京尊龙生物科学有限公司 | Pyraphione compound active insecticide |
| CN101156579A (en) * | 2007-11-19 | 2008-04-09 | 广西田园生化股份有限公司 | Compound agricultural chemical |
| CN101243798A (en) * | 2008-01-11 | 2008-08-20 | 湖南万家丰科技有限公司 | Insecticidal composition containing indoxacarb |
-
2008
- 2008-09-12 CN CN2008102119630A patent/CN101352169B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1925749A (en) * | 2004-03-16 | 2007-03-07 | 辛根塔参与股份公司 | Pesticidal composition and method for seed treatment |
| CN101027991A (en) * | 2007-04-04 | 2007-09-05 | 南京尊龙生物科学有限公司 | Pyraphione compound active insecticide |
| CN101156579A (en) * | 2007-11-19 | 2008-04-09 | 广西田园生化股份有限公司 | Compound agricultural chemical |
| CN101243798A (en) * | 2008-01-11 | 2008-08-20 | 湖南万家丰科技有限公司 | Insecticidal composition containing indoxacarb |
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| CN101352169A (en) | 2009-01-28 |
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