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CN101297679A - Feedstuff additive for improving immunity of livestock and poultry and preparation thereof - Google Patents

Feedstuff additive for improving immunity of livestock and poultry and preparation thereof Download PDF

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Publication number
CN101297679A
CN101297679A CNA2007100586183A CN200710058618A CN101297679A CN 101297679 A CN101297679 A CN 101297679A CN A2007100586183 A CNA2007100586183 A CN A2007100586183A CN 200710058618 A CN200710058618 A CN 200710058618A CN 101297679 A CN101297679 A CN 101297679A
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China
Prior art keywords
vitamin
livestock
cobastab
percent
immunity
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Pending
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CNA2007100586183A
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Chinese (zh)
Inventor
王连民
刘珂飞
张旭
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Tianjin Shengji Group Co Ltd
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Tianjin Shengji Group Co Ltd
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Priority to CNA2007100586183A priority Critical patent/CN101297679A/en
Publication of CN101297679A publication Critical patent/CN101297679A/en
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Abstract

The invention relates to a feed additive for enhancing immunity of livestock and poultry and a preparation method thereof, in particular to a feed additive for enhancing immunity of livestock and poultry and promoting the livestock and poultry to grow and the preparation method thereof, which are characterized by consisting of the following ingredients according to weight percentage: prebiotics of 10 to 50 percent, water-soluble vitamin A of 0.5 to 5 percent, water-soluble vitamin D [3] of 0.1 to 1 percent, water-soluble vitamin E of 1.0 to 3 percent, vitamin K [3] of 0.5 to 1.5 percent, vitamin B [1] of 0.2 to 1.0 percent, vitamin B [2] of 1 to 5 percent, calcium pantothenate of 2 to 5 percent, nicotine acid of 2 to 5 percent, vitamin B [12] of 0.005 to 0.02 percent, folic acid of 0.02 to 0.08 percent, and remainder is supplementary material. The feed additive is added according to the 0.4 millesimal of the feed weight, can prevent the occurrence of diseases by further adjusting the balance of the intestinal tract bacteria colony, supplementing nutrition, and enhancing resistivity of organism, and simultaneously promote the growth of the livestock and poultry. The additive promotes feed digestion and absorption, has the functions of nutrition, health care, and preventing and treating the diseases, and has low cost and safety, no resistance to drugs, no drug residue in the meat and eggs, thus being an ideal feed additive for enhancing the immunity of the livestock and poultry.

Description

A kind of feed addictive that improves immunity of livestock and preparation method thereof
Technical field
The present invention relates to a kind of feed addictive that improves immunity of livestock and preparation method thereof, particularly a kind of feed addictive immunity of livestock, the promotion growth and preparation method thereof that improves.
Background technology
The reason of livestock and poultry diarrhea mainly contains two aspects: on the one hand, enzyme is relatively poor in the phase of reaching maturity of gastrointestinal tract of livestock and fowls activity, but nutritional need is higher relatively, and the enteron aisle burden is heavy, causes the stomach and intestine regulative mechanism relatively poor, and immunologic function also descends relatively; On the other hand, because temperature is sometimes hot and sometimes cold, pathogenic microorganisms is bred in a large number, the easier trouble intestines problem of livestock and poultry in autumn, and for example, the fryer necrotic enteritis once took place in some areas, had caused bigger economic loss for vast chicken farm (family).In fact, in the breeding process of fryer, kind chicken, laying hen, pig, duck, goose, ox etc., because the enteritis based on Escherichia coli, salmonella infection that season in autumn, reason was caused is also very general.Keep the relative equilibrium stable state again because the animal and bird intestines flora forms, and with livestock and poultry in the long-term evolution process, significant to animal growth and development and resist the disease, in case dysequilibrium production performance decline just can occur or disease takes place.Under the normal condition, dominant population is an anaerobic bacteria in the animal intestinal, accounts for more than 99%, wherein mainly comprises bacteroid, Bifidobacterium, Bacillus acidi lactici, digestion bacillus, excellent bacillus etc.; And aerobic bacteria and facultative anaerobe only account for 1%.Change as this dominant population, above-mentioned obligate anaerobe can significantly reduce, and aerobic bacteria and facultative anaerobe increase, and this moment, the livestock and poultry immunity of organisms descended, and caused the generation of disease.
In decades, adding antibiotic in the feed is preventing Animal diseases, is resisting obtained remarkable result such as the aspect that stress, improve breeding performonce fo animals obvious to all, but the antibiotic shortcoming is both to have killed harmful bacterium, also kill beneficial bacterium, harmful bacterium is developed immunity to drugs and increase dosage, animal products is produced harmful effect, and antibiotic long-term and extensive use has caused that gut flora is unbalance, medicament residue, drug resistance and negative effects such as transmission and propagation thereof.
In recent years, development along with biotechnology and microbiological industry, some microecologic regulators arise at the historic moment as antibiotic substitute in the feed, as active bacteria formulation (probio) and prebiotics (compound sugar) etc., microecological balance promotes growth of animal in the animal intestinal by keeping for they, improves animal body immunity and production performance.At present, extensively research and the application in feed of probio and prebiotics, but exist collaborative or antagonism between different probios or the prebiotics and between prebiotics and antibiotic, probio and other trophism or the non-nutritive additive, seek of the interpolation combination of these novel fodder additive the bests, become one of focus of feed research with effect.
Probio mainly is an active bacteria formulation, and they are difficult under the advantage function of the primary flora of alimentary canal field planting at short notice and get off; Active bacteria formulation needs specific micro-ecological environment to satisfy the needs of propagation, and stands the effect at different environment positions; The processing of active bacteria formulation and service condition and time restriction are more, and compatibility is poor.
Prebiotics is the growth of the interior beneficial bacterium of stimulation of host animal alimentary canal selectively, thereby animal is produced the food of advantageous effect or the indigestible composition in the feed, comprises compound sugar, little algae (as spirulina, arthrospira) etc.Compound sugar is the carbohydrate that is formed straight chain and side chain by 2~10 monose molecules by glycosidic bond, the digestive ferment that they are difficult in the animal body is degraded, can directly enter enteron aisle, as beneficial microorganism nutrition substrate, promote enteron aisle beneficial microorganism propagation, suppress the harmful microbe growth, thereby improve the intestinal microecology environment; The compound sugar of research and application has mannosan (MOS), FOS (FOS), xylo-oligosaccharide (XOS), galactooligosaccharide (GOS), oligoisomaltose (IOS), soyabean oligosaccharides (SBOS) etc. in the feed.Prebiotics (compound sugar) has direct physiology and physical function concurrently, has avoided a processing deficiency of using of probiotic active bacteria formulation, is easy to large-scale production.
Summary of the invention
The objective of the invention is to overcome the deficiency of above-mentioned technology, a kind of feed addictive that improves immunity of livestock and preparation method thereof is provided, prebiotics and multivitamin are contained in its inside, vitamin is that animal is kept the necessary organic substance of normal activities, the metabolic process of indirect regulation material in body, though animal to the requirement of vitamin seldom, normally in milligram or microgram, but its effect is very important, because vitamin is damaged easily, perhaps summer vitamin seriously run off, cause animal body hypovitaminosis easily, resistance descends.And prebiotics and vitamin compatibility are better, so with the usefulness of vitamin enrichment probiotic, reduce antibiotic consumption.
For achieving the above object, the technical solution adopted in the present invention is as follows:
A kind of feed addictive that improves immunity of livestock is characterized in that percentage consists of by weight: prebiotics 10-50%, Solvisyn-A 0.5-5%, water soluble vitamin D 30.1-1%, watermiscible vitamin E 1.0-3%, vitamin K 30.5-1.5%, Cobastab 10.2-1.0%, Cobastab 21-5%, calcium pantothenate 2-5%, nicotinic acid 2-5%, Cobastab 120.005%-0.02%, folic acid 0.02-0.08%, surplus is an auxiliary material.
A kind of feed addictive that improves immunity of livestock is characterized in that the percentage best group becomes by weight: prebiotics 25%, Solvisyn-A 3%, water soluble vitamin D 30.4%, watermiscible vitamin E 1.5%, vitamin K 30.5%, Cobastab 10.2%, Cobastab 21.5%, calcium pantothenate 2%, nicotinic acid 3%, Cobastab 120.01%, folic acid 0.05%, surplus is an auxiliary material.
Described prebiotics is at least a in FOS, Oligomeric manna sugar, oligomeric malto-oligosaccharide, the low ficoll.
Described auxiliary material is at least a in sucrose, oral glucose, the DEXTROSE ANHYDROUS.
A kind of preparation method who improves the feed addictive of immunity of livestock is characterized in that comprising the steps:
(1) percentage is packed as a packing with the 10-50% prebiotics is airtight by weight, and the packing instructions moisture resistance is good,
(2) percentage takes by weighing Solvisyn-A 0.5-5% after sieving, water soluble vitamin D by weight 30.1-1%, watermiscible vitamin E 1.0-3%, vitamin K 30.5-1.5%, Cobastab 10.2-1.0%, Cobastab 21-5%, calcium pantothenate 2-5%, nicotinic acid 2-5%, Cobastab 120.005%-0.02%, folic acid 0.02-0.08%, surplus is an auxiliary material, mixes, packing becomes another packing,
(3) two packings are combined in the packing, promptly make a kind of feed addictive that improves immunity of livestock.
Described auxiliary material is at least a in sucrose, oral glucose, the DEXTROSE ANHYDROUS.
Described prebiotics is at least a in FOS, Oligomeric manna sugar, oligomeric malto-oligosaccharide, the low ficoll.
The characteristic of additive component:
Prebiotics: be called as compound sugar, can impel the intestinal microecology system to transform, strengthen the multiplication capacity of profitable strains such as Bifidobacterium and Bacillus acidi lactici, bring into play indirect immunization to helping animal health growth aspect, suppress pathogen breeding and field planting, strengthen the anti-infectious immunity ability.
Water soluble vitamin, water soluble vitamin D 3, watermiscible vitamin E, vitamin K 3, Cobastab 1, Cobastab 2, calcium pantothenate, nicotinic acid, Cobastab 12, folic acid is the vitamin that livestock and poultry often lack, the energy that produces in catabolic process is very little, constituent that neither the body tissue structure, its main biological action are to participate in the coenzyme of body endoenzyme or the composition of prothetic group, indirect regulation material metabolic process in vivo.
The present invention be with multivitamin and prebiotics by a certain percentage compatibility form.
VAD, make mucosal tissue generation pathologies such as eyes, respiratory tract, alimentary canal, resistance against diseases descends, the chance that infects increases, so keep the integrality of skin and epithelial tissue by replenishing vitamins A, promote the synthetic of mucopolysaccharide, can repair the impaired mucosal tissue of animal body, recover the innate immunity barrier of body.
The livestock and poultry D that is deficient in vitamin 3, being usually expressed as rickets and osteoporosis (growing up), poultry produces soft-shelled egg, eggshell thinning etc.; Vitamin E helps the formation of ubiquinone, and has the generation that promotes immune protein, improves body resistance against diseases.
The beneficial effect that the present invention had:
This product is with prebiotics and vitamin organic assembling, and the two complements each other, and can bring into play the enhancing immunity function of probiotic to greatest extent.Prebiotics and vitamin compatibility are better, so with the usefulness of vitamin enrichment probiotic, reduce antibiotic consumption.Use this additive, can promote intestinal beneficial bacterium propagation, balance anaerobic bacteria and aerobic bacteria ratio are supplemented with bacteria group rapidly, improve immunity of organisms, promote animal health, growth apace, the production performance of raising livestock and poultry, the price of deed that increases.The present invention guarantees animal and bird intestines health to the full extent, and is economical and practical.
The specific embodiment
Below in conjunction with specific embodiment this explanation is further described.
Embodiment 1:
A kind of feed addictive that improves immunity of livestock, percentage consists of by weight: FOS 25kg, Solvisyn-A 3kg, water soluble vitamin D 30.4kg, watermiscible vitamin E 1.5kg, vitamin K 30.5kg, Cobastab 10.2kg, Cobastab 21kg, calcium pantothenate 2kg, nicotinic acid 3kg, Cobastab 120.03kg, folic acid 0.05kg, DEXTROSE ANHYDROUS 63.32kg.
Embodiment 2:
A kind of feed addictive that improves immunity of livestock, percentage consists of by weight: Oligomeric manna sugar 50kg, Solvisyn-A 5kg, water soluble vitamin D 31kg, watermiscible vitamin E 3kg, vitamin K 31.5kg, Cobastab 11kg, Cobastab 25kg, calcium pantothenate 5kg, nicotinic acid 5kg, Cobastab 120.02kg, folic acid 0.08kg, oral glucose 23.4kg.
Embodiment 3:
A kind of feed addictive that improves immunity of livestock, percentage consists of by weight: oligomeric maltose 25kg, Solvisyn-A 2kg, water soluble vitamin D 30.5kg, watermiscible vitamin E 2kg, vitamin K 31kg, Cobastab 10.5kg, Cobastab 23kg, calcium pantothenate 2kg, nicotinic acid 5kg, Cobastab 120.01kg, folic acid 0.05kg, sucrose 58.94kg.
Embodiment 4:
A kind of preparation method who improves the feed addictive of immunity of livestock comprises the steps:
(1) percentage takes by weighing the 25kg FOS by weight, airtightly is packed as a packing;
(2) percentage takes by weighing Solvisyn-A 3kg after sieving, water soluble vitamin D by weight 30.4kg, watermiscible vitamin E 1.5kg, vitamin K 30.5kg, Cobastab 10.2kg, Cobastab 21kg, calcium pantothenate 2kg, nicotinic acid 3kg, Cobastab 120.03kg, folic acid 0.05kg, DEXTROSE ANHYDROUS 63.32kg mixes, and packing becomes another packing.
(3) two packings are combined in the packing, promptly make a kind of feed addictive that improves immunity of livestock.
Embodiment 5:
A kind of preparation method who improves the feed addictive of immunity of livestock comprises the steps:
(1) percentage takes by weighing that the 50kg Oligomeric manna sugar is airtight to be packed as a packing by weight;
(2) percentage takes by weighing Solvisyn-A 2kg after sieving, water soluble vitamin D by weight 30.5kg, watermiscible vitamin E 2kg, vitamin K 31kg, Cobastab 10.5kg, Cobastab 23kg, calcium pantothenate 2kg, nicotinic acid 5kg, Cobastab 120.01kg, folic acid 0.05kg, glucose 33.94kg.Mix, packing becomes another packing.
(3) two packings are combined in the packing, promptly make a kind of feed addictive that improves immunity of livestock.
Embodiment 6:
A kind of preparation method who improves the feed addictive of immunity of livestock comprises the steps:
(1) percentage takes by weighing that the 25kg oligomeric maltose is airtight to be packed as a packing by weight;
(2) percentage takes by weighing Solvisyn-A 2kg after sieving, water soluble vitamin D by weight 30.5kg, watermiscible vitamin E 2kg, vitamin K 31kg, Cobastab 10.5kg, Cobastab 23kg, calcium pantothenate 2kg, nicotinic acid 5kg, Cobastab 120.01kg, folic acid 0.05kg, sucrose 58.94kg.
(3) two packings are combined in the packing, promptly make a kind of feed addictive that improves immunity of livestock.
Application experiment and effect:
This additive is pressed 0.4 ‰ heavy amount of feed add, just can be further by adjusting gut flora balance, extra-nutrition, raising Abwehrkraft des Koepers, thus prophylactic generation promotes growth of animals or poultry simultaneously.This additive promotes feed to digest and assimilate, and has the effect of nutrition, health care, prevention and treatment disease.Its inexpensive safety does not develop immunity to drugs, and drug residue free in the meat egg is a kind of feed addictive of desirable raising immunity of livestock.
Table 1 and table 2 are beneficial effects of application experiment of the present invention and generation.
Table 1 adds the influence that this product is grown weanling pig
Index Control group Add 0.4 ‰ groups of this product Only add 0.4 ‰ groups of compound sugar
A test number 28 28 28
First body weight (kg) 9.1 9.1 9.1
Daily gain (g) 505 523 518
Daily ingestion amount (g) 832 859 851
Feed conversion rate 1.65 1.642 1.642
Diarrhea, soft stool are counted 11.1 5.1 5.6
Annotate: diarrhea, soft stool are counted: normal 0, and soft stool 1 point, the mud shape is 2 points just, and watery stool 3 points are mean value in the table.
As can be seen from Table 1, the frequency of adding this product generation diarrhea soft stool pig descends, and daily gain, daily ingestion amount improve.Illustrate that adding this product has the effect that promotes piglet growth.
Table 2 adds the influence of this product to meat chicken production performance
Index Control group Add 0.4 ‰ groups of this product Only add 0.4 ‰ groups of compound sugar
Survival rate (%) 86 96 92
Daily gain (g) 34.28 36.86 35.4
Feedstuff-meat ratio (%) 2.57 2.24 2.4
Diarrhea rate (%) 15.16 1.5 4.9

Claims (5)

1, a kind of feed addictive that improves immunity of livestock is characterized in that percentage consists of by weight: prebiotics 10-50%, Solvisyn-A 0.5-5%, water soluble vitamin D 30.1-1%, watermiscible vitamin E 1.0-3%, vitamin K 30.5-1.5%, Cobastab 10.2-1.0%, Cobastab 21-5%, calcium pantothenate 2-5%, nicotinic acid 2-5%, Cobastab 120.005%-0.02%, folic acid 0.02-0.08%, surplus is an auxiliary material.
2, the feed addictive of raising immunity of livestock according to claim 1 is characterized in that the percentage best group becomes by weight: prebiotics 25%, Solvisyn-A 3%, water soluble vitamin D 30.4%, watermiscible vitamin E 1.5%, vitamin K 30.5%, Cobastab 10.2%, Cobastab 21.5%, calcium pantothenate 2%, nicotinic acid 3%, Cobastab 120.01%, folic acid 0.05%, surplus is an auxiliary material.
3, the feed addictive of raising immunity of livestock according to claim 1 and 2, it is characterized in that described prebiotics is at least a in FOS, Oligomeric manna sugar, oligomeric malto-oligosaccharide, the low ficoll, described auxiliary material is at least a in sucrose, oral glucose, the DEXTROSE ANHYDROUS.
4, a kind of preparation method who improves the feed addictive of immunity of livestock is characterized in that comprising the steps:
(1) percentage is packed as a packing with the 10-50% prebiotics is airtight by weight, and the packing instructions moisture resistance is good,
(2) percentage takes by weighing Solvisyn-A 0.5-5% after sieving, water soluble vitamin D by weight 30.1-1%, watermiscible vitamin E 1.0-3%, vitamin K 30.5-1.5%, Cobastab 10.2-1.0%, Cobastab 21-5%, calcium pantothenate 2-5%, nicotinic acid 2-5%, Cobastab 120.005%-0.02%, folic acid 0.02-0.08%, surplus is an auxiliary material, mixes, packing becomes another packing,
(3) two packings are combined in the packing, promptly make a kind of feed addictive that improves immunity of livestock.
5, the preparation method of the feed addictive of raising immunity of livestock according to claim 4, it is characterized in that described prebiotics is at least a in FOS, Oligomeric manna sugar, oligomeric malto-oligosaccharide, the low ficoll, described auxiliary material is at least a in sucrose, oral glucose, the DEXTROSE ANHYDROUS.
CNA2007100586183A 2007-08-07 2007-08-07 Feedstuff additive for improving immunity of livestock and poultry and preparation thereof Pending CN101297679A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101785535A (en) * 2010-04-08 2010-07-28 山西医科大学 Feed additive containing chicken alpha interferon
CN102318735A (en) * 2011-09-23 2012-01-18 济宁市天瑞通科技开发有限公司 Antibiotic-free mixed feedstuff and preparation method thereof
CN102511680A (en) * 2011-12-19 2012-06-27 张家港市金洲农业科技发展有限公司 Scorpion feed additive
CN102599334A (en) * 2012-02-14 2012-07-25 广西南宁市圣农科技开发有限公司 Chinese medicinal herb feed additive with functions of digestion assistance and disease prevention and cure for livestock and poultry and preparation method of Chinese medicinal herb feed additive
CN103393716A (en) * 2013-07-19 2013-11-20 福建奥姆龙动物药业有限公司 Drug for improving livestock immunity and preparation method of drug
CN103416596A (en) * 2012-05-14 2013-12-04 河北飞龙家禽育种有限公司 Vitamin premix for livestock and poultry
CN103704533A (en) * 2014-01-03 2014-04-09 四川农业大学 Fish feed additive, application method, application and feed containing additive

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101785535A (en) * 2010-04-08 2010-07-28 山西医科大学 Feed additive containing chicken alpha interferon
CN101785535B (en) * 2010-04-08 2012-10-31 山西医科大学 A feed additive containing chicken alpha interferon
CN102318735A (en) * 2011-09-23 2012-01-18 济宁市天瑞通科技开发有限公司 Antibiotic-free mixed feedstuff and preparation method thereof
CN102318735B (en) * 2011-09-23 2013-04-03 济宁市天瑞通科技开发有限公司 Antibiotic-free mixed feedstuff and preparation method thereof
CN102511680A (en) * 2011-12-19 2012-06-27 张家港市金洲农业科技发展有限公司 Scorpion feed additive
CN102599334A (en) * 2012-02-14 2012-07-25 广西南宁市圣农科技开发有限公司 Chinese medicinal herb feed additive with functions of digestion assistance and disease prevention and cure for livestock and poultry and preparation method of Chinese medicinal herb feed additive
CN102599334B (en) * 2012-02-14 2014-03-26 广西南宁市圣农科技开发有限公司 Chinese medicinal herb feed additive with functions of digestion assistance and disease prevention and cure for livestock and poultry and preparation method of Chinese medicinal herb feed additive
CN103416596A (en) * 2012-05-14 2013-12-04 河北飞龙家禽育种有限公司 Vitamin premix for livestock and poultry
CN103393716A (en) * 2013-07-19 2013-11-20 福建奥姆龙动物药业有限公司 Drug for improving livestock immunity and preparation method of drug
CN103704533A (en) * 2014-01-03 2014-04-09 四川农业大学 Fish feed additive, application method, application and feed containing additive
CN103704533B (en) * 2014-01-03 2016-04-27 四川农业大学 Fish meal nutrition prescription, using method, application and the feed containing this nutrition prescription

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