CN101181614B - Medicament for curing podosoma numbness caused by cerebrovascular disease - Google Patents
Medicament for curing podosoma numbness caused by cerebrovascular disease Download PDFInfo
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Abstract
The invention belongs to the technical field of Chinese patent drug, in particular to a medicine for curing numbness over limbs caused by cerebrovascular disease. the invention is mainly made of the following raw materials by weight: 10 to 20g of tall gastrodia tuber, 15 to 30g of gambir plant, 20 to 50g of fresh abalone, 10 to 15g of pinellia tuber, 10 to 15g of arissarmatis, 10 to 20g of fresh largehead atractylodesrhizome, 10 to 30g of indian buead, 10 to 15g of tangerine peel, 10 to 30g of white paeony root, 10 to 30g of radix achyranthis bidentatae, 10 to 20g of fructus cormi, 15 to 30g of angelica, 15 to 30g of taxillus twig, 10 to 30g of eucommia bark, 20 to 50g of fresh radix astragali, 15 to 30g of radix codonopsitis, 5 to 15g of cassia twig, 3 to 9g of scorpion, 3 to 5g of chilopod, 10 to 15g of fructus zizyphi and 6 to 10g of ginger. The invention has remarkable effect for curing numbness over limbs caused by cerebrovascular disease, thereby eliminating the suffering of chronic diseases for numerous patients.
Description
Technical field:
The invention belongs to Chinese patent drug technique field, especially a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease.
Background technology:
Podosoma numbness caused by cerebrovascular disease, comparatively common clinically, be one of medical circle pertinacious disease of being difficult to thoroughly overcome.When cerebrovascular damaged the cortex of brain stem, thalamus, capsula interna, postcentral gyrus and top, the nerve fiber in the sense of touch pathway, conductive beam, nucleus or cortical centre were involved, thereby cause the numb limbs and tense tendons of corresponding site.The characteristics of this class numbness mostly are intercrossing numbness, pathological changes offside hemianesthesia, numb limbs and tense tendons of pathological changes offside or serve as obvious with the far-end numb limbs and tense tendons.Doctor trained in Western medicine is many often to produce little effect based on symptomatic treatment, and obstinate can not fundamentally be removed patient's misery, the patient is enjoyed decoct.
Summary of the invention:
The invention provides a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, it improved should disease cure rate, the hardship for numerous patients remove persistent ailment has solved problems of the prior art.
The present invention solves the problems of the technologies described above the technical scheme that is adopted to be: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, mainly make: Rhizoma Gastrodiae 10～20g, Ramulus Uncariae Cum Uncis 15～30g by the following raw materials in weight medicine, Concha Haliotidis 20～50g, the Rhizoma Pinelliae 10～15g, Rhizoma Arisaematis 10～15g, Rhizoma Atractylodis Macrocephalae 10～20g, Poria 10～30g, Pericarpium Citri Reticulatae 10～15g, the Radix Paeoniae Alba 10～30g, Radix Achyranthis Bidentatae 10～30g, Fructus Corni 10～20g, Radix Angelicae Sinensis 15～30g, Herba Taxilli 15～30g, the Cortex Eucommiae 10～30g, Radix Astragali 20～50g, Radix Codonopsis 15～30g, Ramulus Cinnamomi 5～15g, Scorpio 3～9g, Scolopendra 3～5g, Fructus Jujubae 10～15g, Rhizoma Zingiberis Recens 6～10g.
The medicine of above-mentioned treatment podosoma numbness caused by cerebrovascular disease, preferably the consumption of each crude drug is: Rhizoma Gastrodiae 20g, Ramulus Uncariae Cum Uncis 30g, Concha Haliotidis 50g, Rhizoma Pinelliae 15g, Rhizoma Arisaematis 15g, Rhizoma Atractylodis Macrocephalae 20g, Poria 30g, Pericarpium Citri Reticulatae 15g, Radix Paeoniae Alba 30g, Radix Achyranthis Bidentatae 30g, Fructus Corni 20g, Radix Angelicae Sinensis 30g, Herba Taxilli 30g, Cortex Eucommiae 30g, Radix Astragali 50g, Radix Codonopsis 30g, Ramulus Cinnamomi 15g, Scorpio 9g, Scolopendra 5g, Fructus Jujubae 15g, Rhizoma Zingiberis Recens 10g.
The present invention is made for pure Chinese medicine, and dosage form can be the above any dosage form of pharmaceutics.Commonly used is decoction or oral liquid.Preparation method of the present invention is as follows: take by weighing each crude drug by weight proportion, with the abundant mix homogeneously of each crude drug, soaked 1 hour, steaming and decocting secondary in steam-jacked kettle boiled 45～55 minutes at every turn; Merge secondary filtrate, about 10～12 hours of quiescent setting, get after the supernatant decocting and concentrating decoction, divide the bottle of packing into, vapor sterilization promptly gets oral liquid then.
Other dosage form is produced according to a conventional method and is got final product.
Modern pharmacological research proves:
Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Concha Haliotidis: three medicines are all liver wind calming drug.Rhizoma Gastrodiae: endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG.The property sweet flat, be the medicine of Liver Channel edema caused by disorder of QI, so the title of " controlling bearing's medicine " is arranged.This product aid yang qi is mended five kinds of strain and seven kinds of impairment, and promoting blood circulation is had one's ideas straightened out, and is the main medicine of treatment numb limbs and tense tendons.No matter numb limbs and tense tendons such as cold, heat through suitable compatibility, all can be used.Studies show that: Rhizoma Gastrodiae contains gastrodine, gastrodin unit, polysaccharide and micro-alkaloid, several amino acids etc., can increase the cerebral blood flow of animal, improves cerebral circulation.Numb limbs and tense tendons, dizziness due to the clinical practice Rhizoma Gastrodiae treatment a variety of causes obtain satisfactory effect.In a word, Rhizoma Gastrodiae is best suited for the smooth and numb limbs and tense tendons that causes of QI-blood circulation due to excessive rising of liver-YANG, the essential resistance of turbid phlegm.Can also obviously bring high blood pressure down, blood fat, anticoagulant, tranquilizing soporific, convulsion, slow down aging.Ramulus Uncariae Cum Uncis: endogenous wind stopping relieving convulsion, heat clearing away YANG hyperactivity suppressing.Ramulus Uncariae Cum Uncis is discussed by doctor family, and " hands is fainted cloudy medicine also.Logical pericardium is in edema with the liver involved, and the quiet fire of wind ceases, and then all cards are from removing." so cure mainly the head revolve dizzy, hypertension etc.Pharmacological research shows: Ramulus Uncariae Cum Uncis contains multiple indoles alkaloid, has tangible hypotensive effect, anticoagulant and antithrombotic and forms the formation effect.Concha Haliotidis: suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving.Concha Haliotidis is discussed by doctor family, and " it is little salty to distinguish the flavor of, and slightly cool in nature is the key medicine of cool liver, town liver.Congested work aches, does dizzy in the brain so be apt to control." pharmacological research shows: Concha Haliotidis contains calcium carbonate, gallbladder element and conchiolin and several amino acids.
The Rhizoma Pinelliae, Rhizoma Arisaematis: two medicines are all apophlegmatisant.The Rhizoma Pinelliae: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.The property of this product tool warm-dryness syndrome can dampness and reduce phlegm, for controlling the key medicine of damp-phlegm.Pharmacological research shows: the Rhizoma Pinelliae contains alkaloids such as volatile oil, choline, several amino acids, Saponin, sanedrine.Have blood fat reducing, antiarrhythmic effect, breathing, digestive system disease are had better curative effect.Rhizoma Arisaematis: drying dampness to eliminate phlegm, expelling wind and relieving convulsion.Pharmacological research shows: Rhizoma Arisaematis contains multiple inorganic elementss such as triterpenoid saponin, aminoacid, cupreol and calcium, magnesium, aluminum, zinc.Have eliminate the phlegm, convulsion, calmness, analgesic activity, also can treat arrhythmia, cervical cancer." Rhizoma Pinelliae is specially walked the intestines and stomach to the argumentation of doctor family, and Rhizoma Arisaematis is specially walked meridians.The special main warp network of Rhizoma Arisaematis wind-phlegm, the special main the intestines and stomach damp-phlegm of the Rhizoma Pinelliae.
Rhizoma Atractylodis Macrocephalae, Radix Astragali, Radix Codonopsis: three medicines are all and are Qi-tonifying drug.Rhizoma Atractylodis Macrocephalae: sweet in the mouth, hardship, warm in nature.Bitter can dampness, sweet can tonification and in, go into taste two warps again.Its performance and spleen fortuneization are liked the wet property of dry evil and are harmonious, so is the key medicine of spleen reinforcing.Pharmacological research shows: Rhizoma Atractylodis Macrocephalae contains volatile oil, mannan, fructose and several amino acids.Have the gastrointestinal function of enhancing, promote secretion of urine, enhancing human body immunity function.Radix Astragali: sweet in the mouth, slightly warm in nature.Panacea for QI invigorating.Strengthening the spleen gas, tonifying the lung gas; But benefiting qi and nourishing blood, the effect of a blood stasis removing eliminating stagnation.Pharmacological research shows: Radix Astragali contains compositions such as polysaccharide component, flavone compound, triterpene astragalin, aminoacid and trace element.Have the human body immunity improving function, obviously improve hemorheology, protection hemopoietic system, improve the ability that the myocardial cell anti-hypoxia lacks sugar, also have gastrointestinal function, the antitumor of enhancing and prevent and treat effect such as osteoporosis.Radix Codonopsis: sweet in the mouth, slightly warm in nature.Key medicine for the treatment asthenia of pulmonosplenic qi.But benefiting QI and nourishing blood " nourishes blood and does not grow greasyly partially, the beneficial will effect of better calming the nerves is arranged.Pharmacological research shows: Radix Codonopsis contains materials such as saccharide, tangshenoside, codonopsine, volatile oil, flavonoid, aminoacid and trace element.Have enhance immunity systemic effect, anti-stress effect, inhibition inside and outside thrombosis, promote memory effect, antagonism superoxide radical damaging action, also have the gastrointestinal motility of adjustment, protect the liver, effect such as calm, anticancer and anti-inflammation.
Poria: be damp-clearing drug.Sweet in the mouth, light, property is flat." Poria simply, for controlling the expectorant principal agent.Expectorant this, water also, Poria can be gone water; Expectorant is moving, wets also, and Poria can be gone wet again." pharmacological research shows: Poria contains β-pachyman, pachymaran, pachymic acid, su-fuling, histidine, choline etc.Has the enhancing human body immunity function, adjust gastrointestinal function, promote the water-electrolyte metabolism function of body also have mind tranquilizing and the heart calming, antitumor, protect the liver and effect such as antibiotic.
Pericarpium Citri Reticulatae: be QI regulating medicine.Bitter in the mouth, property suffering, temperature.For lung, spleen two medicine through edema caused by disorder of QI, circulation of qi promoting preferably, dampness, the effect of reducing phlegm are arranged, be used for the impaired depurative descending of lung QI of retention of damp leading to blockage of QI expectorant due to coagulating, the card of dysfunction of the spleen in transportation.Pharmacological research shows: Pericarpium Citri Reticulatae contains volatile oil and hesperidin, Nobiletin, inositol and vitamin C, B
1Deng.Have and suppress gastrointestinal smooth muscle contraction, anti-gastric-ulcer, hepatic cholagogic, eliminate the phlegm, relieving asthma, improve cardiac hemodynamic, rising blood pressure, also have effects such as cholesterol reducing, antibiotic, antiviral, antioxidation.
The Radix Paeoniae Alba, Radix Angelicae Sinensis: two medicines are all hematonic.The Radix Paeoniae Alba: bitter in the mouth, acid, cold nature.The effect yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, suppressing liver-YANG.Be the key medicine of enriching blood, have and enrich blood and and blood vessels effect.Pharmacological research shows: Radix Paeoniae Alba main component comprises paeoniflorin, hydroxypaeoniflorin, peony lactone glycoside, benzoylpaeoniflorin, paeoniflorin and paeonol.Also contain volatile oil and triterpenoid compound etc.Have antithrombotic, anticoagulant, raising function of immune system, also have effects such as the analgesia of protecting the liver, spasmolytic, anti-inflammatory, antibacterial antiviral.Radix Angelicae Sinensis: sweet in the mouth, warm in nature.Be the gas medicine in the blood, the promoting the circulation of blood of enriching blood, tonifying five ZANG-organs, granulation promoting meat.Pharmacological research shows: Radix Angelicae Sinensis contains Rhizoma Ligustici lactone, n-butene lactone, angelicone, ferulic acid, polysaccharide, several amino acids, vitamin and inorganic elements.Have blood vessel dilating, anticoagulant, antithrombotic formation, blood fat reducing, promotion hemopoietic function, human body immunity improving function, resist myocardial ischemia, the dementia effect, also have protect the liver, anti-radiation, anti-damage, antitumor, anti-inflammatory analgesic and purging and intestine lubricating action.
Radix Achyranthis Bidentatae: be blood circulation and stasis-eliminating medicine.Bitter in the mouth, acid, property is flat.Blood circulation promoting and blood stasis dispelling power is stronger, " all diseases of stagnation of QI-blood of leading ".The merit that nourishing the liver and kidney, strengthening the tendons and bones are arranged, " power of its nourishing, also " as power more than the cattle.Pharmacological research shows: Radix Achyranthis Bidentatae contains triterpenoid saponin, polysaccharide, glycopeptide, ecdysterone, inokosterone, alkaloids and coumarin etc.Have the protein assimilation of enhancing, delaying senility function, enhance immunity effect, memory reinforcing and endurance, blood sugar lowering effect, also have effects such as anti-inflammatory analgesic, anti-I type herpes simplex virus.
Fructus Corni: be astringent medicinal.Sour in the mouth, puckery, slightly warm in nature.Have liver and kidney tonifying, kidney-Yang invigorating adds marrow, effects such as brute force.Pharmacological research shows: Fructus Corni contains Fructus Corni glycoside, Saponin, tannin class, ursolic acid and vitamin A, iridoid glycosides etc.Have the content of hemoglobin of increasing, physical strength reinforcing, Fructus Alpiniae Oxyphyllae, blood fat reducing, blood sugar lowering, the anticoagulant effect also has effects such as heart tonifying, shock, antiinflammatory, and body's immunity is had two-way function.
Herba Taxilli: be medicine for rheumatism.Bitter in the mouth, property is flat.Be longer than invigorating the liver and kidney, bone and muscle strengthening.Pharmacological research shows: Herba Taxilli contains oleanolic acid, B-Amyrin, meso inositol, flavone compound, Quercetin, avacularin etc.Have blood pressure lowering, diuresis, also have heart contraction, calmness and the antivirus action of enhancing.
The Cortex Eucommiae: be yang-tonifying drug.Sweet in the mouth, warm in nature.Liver and kidney tonifying is arranged, bone and muscle strengthening, invigorating middle warmer, beneficial vital essence, effects such as Qiang Zhi.Pharmacological research shows: the Cortex Eucommiae contains lignin, aucubin, chlorogenic acid, Cortex Eucommiae sugar A, Cortex Eucommiae sugar B, flavone compound, several amino acids, fatty acid, vitamin and trace element etc.Have blood pressure lowering, blood fat reducing, diuresis, enhancing human body immunity function, also have effects such as the osteocyte of enhancing propagation, defying age, antitumor, function of gallbladder promoting, anti-inflammation.
Ramulus Cinnamomi: be wind-cold-dispersing medicinal.Acrid in the mouth, sweet, warm in nature.Xin Wenhang looses, and reaches battalion thoroughly and defends; Be apt to into blood system, be the key medicine of warm promoting blood circulation.Pharmacological research shows: Ramulus Cinnamomi contains volatile oil, anti-glycoside cinnamic acid, coumarin, phlegmatic temperament and resin etc.Having increases the myocardial nutritional flow amount, improves cardiac function, increases coronary flow, antithrombase effect, also has effects such as antipyretic-antalgic, antibiotic, antiviral, diuresis.
Scorpio, Scolopendra: two medicines are all liver wind calming drug.Scorpio: salty in the mouth, suffering, property is flat, and is poisonous.The endogenous wind stopping relieving convulsion, removing obstruction in the collateral to relieve pain, detoxicating and resolving stagnation of pathogens.Pharmacological research shows: Scorpio contains scorpion venom, various kinds of amine and amino acids, cholesterol, phosphatidylcholine and multiple fatty acid.Have antithrombotic and form, effects such as convulsion, epilepsy, antitumor and analgesia are also arranged.Scolopendra; Acrid in the mouth, warm in nature, poisonous.The endogenous wind stopping relieving convulsion, detoxicating and resolving stagnation of pathogens, removing obstruction in the collateral to relieve pain." Scolopendra walks to scurry the power steepest, interior and internal organs, and outer and meridians, all QI and blood cohesion parts all can be opened it." pharmacological research shows: Scolopendra contains scorpion venom (H-subst and dissolved blood protein matter), cruel amino acid, formic acid and cholesterol etc.Have microcirculation improvement and reduce packed cell volume, reduce blood viscosity, effects such as convulsion, antibacterial and antitumor are also arranged.
Podosoma numbness caused by cerebrovascular disease, the traditional Chinese medical science are thought the following reason of having of primary disease.1. suffer unexpected stimulation mentally, or persistent psychentonia, cause heart-fire to be contained cruelly, liver-yang rises suddenly and sharply, fire and wind stirring up each other, QI and blood superinverse and falling ill; 2. surfeit delicious food, excessive drinking, hungry full inappropriate, cause the spleen sun injured, strong fortune mistake department, accumulatively wet raise phlegm, expectorant lies prostrate meridians; 3. nutrient blood loss, muscle arteries and veins cervical carcinoma with cachexia; 4. old asthenia, instability of kidney QI, or labor is desired excessively hepatic and renal YIN deficiency, excessive rising of liver-YANG, QI and blood superinverse, the last illiteracy god of unit; 5. weakness due to chronic disease or innate deficiency, vigour is not filled, and ailment said due to cold or exposure is taken advantage of a weak point, or exogenous wind priming phlegm-damp, numbness resistance channels.Rhizoma Gastrodiae, Ramulus Uncariae Cum Uncis, Concha Haliotidis in the side, suppressing the hyperactive liver and subsiding YANG, dispelling pathogenic wind and eliminating phlegm; Rhizoma Pinelliae drying dampness to eliminate phlegm, the Rhizoma Arisaematis dispelling pathogenic wind and eliminating phlegm, compatibility is to strengthen the effect of eliminating phlegm and calming wind with it; Rhizoma Atractylodis Macrocephalae, Poria invigorating the spleen to clear away damp pathogen are to control the source of living expectorant; The Pericarpium Citri Reticulatae activating QI to eliminate phlegm is played eliminating phlegm and calming wind altogether, the merit of invigorating the spleen to clear away damp pathogen; Radix Paeoniae Alba vital essence replenishing, easing the affected liver relieves dizziness, high fever, infantile convulsions, epilepsy, etc.; The Radix Achyranthis Bidentatae conducting blood to flow downwards is rolled over its yang hyperactivity, and the energy nourishing the liver and kidney; Fructus Corni invigorating the liver and kidney and arresting seminal emission, essence and blood sharing the same origin, with the Radix Angelicae Sinensis compatibility, foster battalion enriches blood; Radix Astragali, Radix Codonopsis strengthening the spleen gas, tonifying the lung gas, invigorating the spleen and replenishing QI; Herba Taxilli, the Cortex Eucommiae are equipped with Radix Achyranthis Bidentatae, invigorating the liver and kidney, bone and muscle strengthening; Ramulus Cinnamomi temperature promoting blood circulation closes the Radix Astragali and escorts table admittedly, with the Radix Paeoniae Alba, Fructus Jujubae, Rhizoma Zingiberis Recens compatibility, harmonizing yingfen and weifen; Scorpio, Scolopendra collateral dredging dispel the wind, and merit poison eliminating stagnation is apt to control the network disease, and to the treatment of numb limbs and tense tendons, effect is better.More than prescription at the cause of disease, is learnt from other's strong points to offset one's weaknesses, and therapeutical effect is strengthened, adverse reaction reduction, to podosoma numbness caused by cerebrovascular disease at one stroke and merit it.Real in capturing the good recipe of primary disease.
For verifying therapeutic effect of the present invention, the present invention has carried out clinical verification to 91 routine cerebrovascular accidents are podosoma numbness caused.The clinical verification that the podosoma numbness caused patient of 91 routine cerebrovascular accidents is carried out successively, all disappear or alleviate greatly in the limbs pain and numbness of taking medicine after 10～60 bottles, hemiplegia, the treatment effective percentage of hemianesthesia is respectively 64.8% and 96.7%, obtains unexpected effect.
Clinical verification:
1, clinical data: the present invention verifies podosoma numbness caused 69 examples of cerebral hemorrhage, podosoma numbness caused 22 examples of cerebral infarction.All cases all meet the podosoma numbness caused by cerebrovascular disease diagnostic criteria.Podosoma numbness caused male 51 examples of cerebral hemorrhage, women 18 examples, 39～72 years old age, 56.4 years old mean age.The elder of the course of disease is for 13 years, and the shortest person had a surplus in 3 months.Podosoma numbness caused male 9 examples of cerebral infarction, women 13 examples, 42～63 years old age, 51.4 years old mean age.The course of disease did not wait in 1～12 year.
2, method: after all case diagnosis are clear and definite, with throwing 5～10 bottles of the present invention, 1 bottle of every day, decoction being taken at a draught or divide and take for 2 times.According to the difference of patient's symptom, on we's basis, can also suitably add and subtract.
3, result:
The podosoma numbness caused patient of 69 routine cerebral hemorrhages, take 10～30 bottles after, numb limbs and tense tendons complete obiteration 32 examples alleviate 35 examples.For consolidating curative effect, advise it to obey 30 bottles again, symptom complete obiteration 52 examples.Cure rate 75.3%, effective percentage 97.1%.Visited 1 year, and do not see recurrence.
The podosoma numbness caused patient of 22 routine cerebral infarction, take 10～30 bottles after, numb limbs and tense tendons complete obiteration 13 examples alleviate 8 examples.For consolidating curative effect, advise it to obey 30 bottles again, symptom complete obiteration 18 examples.Cure rate 81.8%, effective percentage 95.4%.Visited 1 year, and do not see recurrence.
Model case:
Case 1: mutually so-and-so, man, 63 years old, workman.Left limb was gone to a doctor in numb 6 years.The patient because of the thalamic hemorrhage hospitalization takes a turn for the better, still felt the left limb numbness before 6 years after leaving hospital, dizzy, headache is forgetful drowsiness, and being irritable and getting angry easily is taken treatment cerebrovascular medicine for a long time, and curative effect does not show, and comes institute to go to a doctor on July 12nd, 2002.Check: blood pressure 160/105mmHg, sanity, speech is fluent, circle such as isocoria, light reflex exists, ocular fundus arteriosclerosis sign, bilateral nasolabial fold symmetry, it is placed in the middle to loll.Extremity muscular strength, muscular tension are normal, left side hemihypalgesia, bilateral biceps brachii m. and knee jerk symmetry, bilateral Babinski sign feminine gender.The in vain greasy little Huang of dark tongue quality tongue, stringy and rolling pulse.With throwing medicine of the present invention, take 5 bottles after, pain and numbness subtracts greatly, surplus disease alleviates.For consolidating curative effect, advise it to obey 7～10 bottles again, left limb is numb to disappear.Visited 1 year, and do not see recurrence.
Case 2: shut out so-and-so, woman, 54 years old, peasant.Right side numb limbs and tense tendons, prescription on individual diagnosis in unable 2 years.The patient because of the Big Area Cerebral Infarction treatment takes a turn for the better, still felt right side numb limbs and tense tendons, unable, slurred speech before 2 years during prescription on individual diagnosis, dizzy head is heavy, and the xerostomia mouth is sticking, the time convulsion arranged, take treatment cerebrovascular and antiepileptic, poor effect comes institute to go to a doctor on April 23rd, 2003.Check: blood pressure 150/115mmHg, sanity, the imperfection motor aphasia, circle such as isocoria, light reflex exists, ocular fundus arteriosclerosis sign, the right side nasolabial fold is shallow, and right avertence lolls.Right side limbs muscular strength IV level, the muscular tension height, left limb muscular strength, muscular tension are normal, the right side hemihypalgesia, right side biceps brachii m. and knee jerk be greater than the left side, the right side Babinski sign positive.The big tongue of enlarged tongue is thick in vain, thready and rolling pulse.With throwing medicine of the present invention, take 10 bottles after, pain and numbness alleviates, speech is flexible, the convulsion number of times reduces.For consolidating curative effect, advise it to obey 40 bottles again, the right side numb limbs and tense tendons disappears, and flexibly movable, epilepsy is not reaccessed.Followed up a case by regular visits to 1 year, and do not see recurrence.
Case 3: Lee so-and-so, man, 46 years old, workman.Right upper extremity numbness, prescription on individual diagnosis in unable 4 months.The patient because of cerebral infarction therapy takes a turn for the better, now still felt right upper extremity numbness, unable before 5 months, and is nervous, breathe hard, and anemophobia, spontaneous perspiration, medicine treatments such as clothes SHENGMAI YIN, effect does not show, and comes institute's prescription on individual diagnosis on the 18th in JIUYUE in 2003.Check: blood pressure 130/80mmHg, sanity, speech is fluent, circle such as isocoria, light reflex exists, ocular fundus arteriosclerosis sign, bilateral nasolabial fold symmetry, it is placed in the middle to loll.A little less than the right upper extremity muscular strength V level, surplus limbs muscular strength, muscular tension are normal, right upper extremity hypalgesia, bilateral biceps brachii m. and knee jerk symmetry, bilateral Babinski sign feminine gender.Pale tongue with white fur, thready and weak pulse.With throwing medicine of the present invention, take 5 bottles after, pain and numbness alleviates.For consolidating curative effect, advise it to obey 10 bottles again, right upper extremity is numb to disappear, and movable strong, surplus disease knowing removed.Followed up a case by regular visits to 1 year, and do not see recurrence.
Case 4: the king so-and-so, man, 66 years old, teacher.Right side numb limbs and tense tendons, prescription on individual diagnosis in unable 7 years.The patient because of the capable evacuation of intracranial hematoma treatment of cerebral hemorrhage takes a turn for the better, now still felt the right side numb limbs and tense tendons before 7 years, and is movable ineffective, dizziness, order revolves, cardiopalmus, insomnia, take medicines such as treatment cerebrovascular medicine and multivitamin for a long time, unsatisfactory curative effect comes institute to go to a doctor on April 3rd, 2004.Check: blood pressure 170/110mmHg, sanity, the imperfection motor aphasia, the right side nasolabial fold is shallow, and right avertence lolls.Right side limbs muscular strength III level, the muscular tension height, left limb muscular strength, muscular tension are normal, the right side hemihypalgesia, right side biceps brachii m. and knee jerk be greater than the left side, the right side Babinski sign positive.The pale tongue yellow and thin fur, thready and rolling pulse.With throwing medicine of the present invention, take 10 bottles after, right side numb limbs and tense tendons sx.For consolidating curative effect, advise it to obey 50 bottles again, the right side numb limbs and tense tendons disappears, and limb activity is flexible, and surplus disease disappears.Followed up a case by regular visits to 1 year, and do not see recurrence.
Case 5: Lee so-and-so, man, 58 years old, cadre.Left limb numbness, prescription on individual diagnosis in unable 3 years.The patient because of the cerebral hemorrhage expectant treatment takes a turn for the better, now still felt left limb numbness, unable before 3 years, hemiplegia, and the soreness of waist is as folding, and the soft lower limb of knee joint quivers, and takes medicines such as treatment cerebrovascular medicine and LIUWEI DIHUANG WAN for a long time, and effect does not show, and comes institute to go to a doctor May 30 in 2003.Check: blood pressure 150/95mHg, sanity, artistomia, the left side nasolabial fold is shallow slightly, and left avertence lolls.Right side limbs muscular strength, muscular tension are normal, left limb muscular strength IV level, and the muscular tension height, the left side hemihypalgesia, left side biceps brachii m. and knee jerk be greater than the right side, the left side Babinski sign positive.The dark red tongue of tongue is greasy in vain, thready pulse.With throwing medicine of the present invention, take 10 bottles after, the left limb pain and numbness alleviates.For consolidating curative effect, advise it to obey 30 bottles again, left numb limbs and tense tendons disappears, and limb activity is flexible, and surplus disease disappears.Followed up a case by regular visits to 1 year, and do not see recurrence.
The present invention is applicable to hepatic and renal YIN deficiency, contains in the liver-wind stirring up internally, phlegm-damp, and deficiency of both QI and blood, channels is obstructed, hemiplegia, numb limbs and tense tendons, obstinate person.Effective percentage reaches 96.7%, and does not see recurrence.Pure Chinese medicinal preparation, easy and simple to handle, taking convenience, the patient also can make at home.Observe through clinical multiple-case, without any side effects.
The specific embodiment:
For clearly demonstrating technical scheme of the present invention, below by the specific embodiment, the present invention will be described in detail.
Embodiment 1: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, make by the crude drug of following weight: Rhizoma Gastrodiae 20g, Ramulus Uncariae Cum Uncis 30g, Concha Haliotidis 50g, Rhizoma Pinelliae 15g, Rhizoma Arisaematis 15g, Rhizoma Atractylodis Macrocephalae 20g, Poria 30g, Pericarpium Citri Reticulatae 15g, Radix Paeoniae Alba 30g, Radix Achyranthis Bidentatae 30g, Fructus Corni 20g, Radix Angelicae Sinensis 30g, Herba Taxilli 30g, Cortex Eucommiae 30g, Radix Astragali 50g, Radix Codonopsis 30g, Ramulus Cinnamomi 15g, Scorpio 9g, Scolopendra 5g, Fructus Jujubae 15g, Rhizoma Zingiberis Recens 10g.
Manufacturing method for above mentioned medicine is as follows: take by weighing each crude drug by weight proportion, with the abundant mix homogeneously of each crude drug, soaked 1 hour, steaming and decocting secondary in steam-jacked kettle boiled 45～55 minutes at every turn; Merge secondary filtrate, about 10～12 hours of quiescent setting, get after the supernatant decocting and concentrating decoction, divide the bottle of packing into, vapor sterilization promptly gets oral liquid then.
Embodiment 2: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, make by the crude drug of following weight: Rhizoma Gastrodiae 10g, Ramulus Uncariae Cum Uncis 15g, Concha Haliotidis 20g, Rhizoma Pinelliae 10g, Rhizoma Arisaematis 10g, Rhizoma Atractylodis Macrocephalae 10g, Poria 10g, Pericarpium Citri Reticulatae 10g, Radix Paeoniae Alba 10g, Radix Achyranthis Bidentatae 10g, Fructus Corni 10g, Radix Angelicae Sinensis 15g, Herba Taxilli 15g, Cortex Eucommiae 10g, Radix Astragali 20g, Radix Codonopsis 15g, Ramulus Cinnamomi 5g, Scorpio 3g, Scolopendra 3g, Fructus Jujubae 10g, Rhizoma Zingiberis Recens 6g.
Soak time, the time of boiling, quiescent setting time can be done to adapt to and be adjusted in the preparation method, and all the other are with the preparation method of embodiment 1.
Embodiment 3: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, make by the crude drug of following weight: Rhizoma Gastrodiae 12g, Ramulus Uncariae Cum Uncis 15g, Concha Haliotidis 20g, Rhizoma Pinelliae 12g, Rhizoma Arisaematis 12g, Rhizoma Atractylodis Macrocephalae 15g, Poria 18g, Pericarpium Citri Reticulatae 12g, Radix Paeoniae Alba 18g, Radix Achyranthis Bidentatae 18g, Fructus Corni 12g, Radix Angelicae Sinensis 18g, Herba Taxilli 18g, Cortex Eucommiae 18g, Radix Astragali 40g, Radix Codonopsis 25g, Ramulus Cinnamomi 10g, Scorpio 5g, Scolopendra 3g, Fructus Jujubae 10g, Rhizoma Zingiberis Recens 6g.
Soak time, the time of boiling, quiescent setting time can be done to adapt to and be adjusted in the preparation method, and all the other are with the preparation method of embodiment 1.
Embodiment 4: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, make by the crude drug of following weight: Rhizoma Gastrodiae 15g, Ramulus Uncariae Cum Uncis 15g, Concha Haliotidis 30g, Rhizoma Pinelliae 10g, Rhizoma Arisaematis 10g, Rhizoma Atractylodis Macrocephalae 20g, Poria 10g, Pericarpium Citri Reticulatae 10g, Radix Paeoniae Alba 20g, Radix Achyranthis Bidentatae 10g, Fructus Corni 10g, Radix Angelicae Sinensis 15g, Herba Taxilli 20g, Cortex Eucommiae 10g, Radix Astragali 50g, Radix Codonopsis 15g, Ramulus Cinnamomi 5g, Scorpio 5g, Scolopendra 5g, Fructus Jujubae 10g, Rhizoma Zingiberis Recens 10g.
Soak time, the time of boiling, quiescent setting time can be done to adapt to and be adjusted in the preparation method, and all the other are with the preparation method of embodiment 1.
Embodiment 5: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, make by the crude drug of following weight: Rhizoma Gastrodiae 18g, Ramulus Uncariae Cum Uncis 25g, Concha Haliotidis 35g, Rhizoma Pinelliae 12g, Rhizoma Arisaematis 12g, Rhizoma Atractylodis Macrocephalae 18g, Poria 25g, Pericarpium Citri Reticulatae 12g, Radix Paeoniae Alba 25g, Radix Achyranthis Bidentatae 25g, Fructus Corni 18g, Radix Angelicae Sinensis 25g, Herba Taxilli 25g, Cortex Eucommiae 25g, Radix Astragali 35g, Radix Codonopsis 25g, Ramulus Cinnamomi 10g, Scorpio 6g, Scolopendra 5g, Fructus Jujubae 5g, Rhizoma Zingiberis Recens 10g.
Soak time, the time of boiling, quiescent setting time can be done to adapt to and be adjusted in the preparation method, and all the other are with the preparation method of embodiment 1.
Embodiment 6: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, make by the crude drug of following weight: Rhizoma Gastrodiae 10g, Ramulus Uncariae Cum Uncis 15g, Concha Haliotidis 20g, Rhizoma Pinelliae 10g, Rhizoma Arisaematis 10g, Rhizoma Atractylodis Macrocephalae 20g, Poria 30g, Pericarpium Citri Reticulatae 10g, Radix Paeoniae Alba 10g, Radix Achyranthis Bidentatae 10g, Fructus Corni 10g, Radix Angelicae Sinensis 15g, Herba Taxilli 30g, Cortex Eucommiae 10g, Radix Astragali 50g, Radix Codonopsis 30g, Ramulus Cinnamomi 10g, Scorpio 9g, Scolopendra 5g, Fructus Jujubae 15g, Rhizoma Zingiberis Recens 10g.
Soak time, the time of boiling, quiescent setting time can be done to adapt to and be adjusted in the preparation method, and all the other are with the preparation method of embodiment 1.
Embodiment 7: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, make by the crude drug of following weight: Rhizoma Gastrodiae 20g, Ramulus Uncariae Cum Uncis 30g, Concha Haliotidis 50g, Rhizoma Pinelliae 10g, Rhizoma Arisaematis 10g, Rhizoma Atractylodis Macrocephalae 10g, Poria 10g, Pericarpium Citri Reticulatae 10g, Radix Paeoniae Alba 30g, Radix Achyranthis Bidentatae 30g, Fructus Corni 20g, Radix Angelicae Sinensis 30g, Herba Taxilli 20g, Cortex Eucommiae 20g, Radix Astragali 30g, Radix Codonopsis 15g, Ramulus Cinnamomi 5g, Scorpio 9g, Scolopendra 5g, Fructus Jujubae 15g, Rhizoma Zingiberis Recens 6g.
Soak time, the time of boiling, quiescent setting time can be done to adapt to and be adjusted in the preparation method, and all the other are with the preparation method of embodiment 1.
Embodiment 8: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, make by the crude drug of following weight: Rhizoma Gastrodiae 20g, Ramulus Uncariae Cum Uncis 30g, Concha Haliotidis 50g, Rhizoma Pinelliae 10g, Rhizoma Arisaematis 10g, Rhizoma Atractylodis Macrocephalae 20g, Poria 10g, Pericarpium Citri Reticulatae 10g, Radix Paeoniae Alba 10g, Radix Achyranthis Bidentatae 10g, Fructus Corni 10g, Radix Angelicae Sinensis 20g, Herba Taxilli 15g, Cortex Eucommiae 10g, Radix Astragali 30g, Radix Codonopsis 15g, Ramulus Cinnamomi 10g, Scorpio 5g, Scolopendra 3g, Fructus Jujubae 10g, Rhizoma Zingiberis Recens 10g.
Soak time, the time of boiling, quiescent setting time can be done to adapt to and be adjusted in the preparation method, and all the other are with the preparation method of embodiment 1.
Embodiment 9: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, make by the crude drug of following weight: Rhizoma Gastrodiae 10g, Ramulus Uncariae Cum Uncis 15g, Concha Haliotidis 20g, Rhizoma Pinelliae 10g, Rhizoma Arisaematis 10g, Rhizoma Atractylodis Macrocephalae 10g, Poria 10g, Pericarpium Citri Reticulatae 10g, Radix Paeoniae Alba 10g, Radix Achyranthis Bidentatae 10g, Fructus Corni 10g, Radix Angelicae Sinensis 15g, Herba Taxilli 15g, Cortex Eucommiae 10g, Radix Astragali 50g, Radix Codonopsis 30g, Ramulus Cinnamomi 5g, Scorpio 3g, Scolopendra 3g, Fructus Jujubae 10g, Rhizoma Zingiberis Recens 6g.
Soak time, the time of boiling, quiescent setting time can be done to adapt to and be adjusted in the preparation method, and all the other are with the preparation method of embodiment 1.
Embodiment 10: a kind of medicine for the treatment of podosoma numbness caused by cerebrovascular disease, make by the crude drug of following weight: Rhizoma Gastrodiae 15g, Ramulus Uncariae Cum Uncis 15g, Concha Haliotidis 30g, Rhizoma Pinelliae 10g, Rhizoma Arisaematis 15g, Rhizoma Atractylodis Macrocephalae 15g, Poria 15g, Pericarpium Citri Reticulatae 15g, Radix Paeoniae Alba 20g, Radix Achyranthis Bidentatae 30g, Fructus Corni 20g, Radix Angelicae Sinensis 15g, Herba Taxilli 30g, Cortex Eucommiae 30g, Radix Astragali 30g, Radix Codonopsis 30g, Ramulus Cinnamomi 10g, Scorpio 6g, Scolopendra 4g, Fructus Jujubae 5g, Rhizoma Zingiberis Recens 10g.
Soak time, the time of boiling, quiescent setting time can be done to adapt to and be adjusted in the preparation method, and all the other are with the preparation method of embodiment 1.
The described weight proportion of above-mentioned embodiment can not be as the basis of restriction protection domain of the present invention.
Claims (2)
1. treat cerebral hemorrhage or the podosoma numbness caused medicine of brain jam for one kind, it is characterized in that: make: Rhizoma Gastrodiae 10～20g, Ramulus Uncariae Cum Uncis 15～30g by the following raw materials in weight medicine, Concha Haliotidis 20～50g, the Rhizoma Pinelliae 10～15g, Rhizoma Arisaematis 10～15g, Rhizoma Atractylodis Macrocephalae 10～20g, Poria 10～30g, Pericarpium Citri Reticulatae 10～15g, the Radix Paeoniae Alba 10～30g, Radix Achyranthis Bidentatae 10～30g, Fructus Corni 10～20g, Radix Angelicae Sinensis 15～30g, Herba Taxilli 15～30g, the Cortex Eucommiae 10～30g, Radix Astragali 20～50g, Radix Codonopsis 15～30g, Ramulus Cinnamomi 5～15g, Scorpio 3～9g, Scolopendra 3～5g, Fructus Jujubae 10～15g, Rhizoma Zingiberis Recens 6～10g.
2. a kind of cerebral hemorrhage or podosoma numbness caused medicine of brain jam for the treatment of according to claim 1, it is characterized in that: wherein the consumption of each crude drug is: Rhizoma Gastrodiae 20g, Ramulus Uncariae Cum Uncis 30g, Concha Haliotidis 50g, Rhizoma Pinelliae 15g, Rhizoma Arisaematis 15g, Rhizoma Atractylodis Macrocephalae 20g, Poria 30g, Pericarpium Citri Reticulatae 15g, Radix Paeoniae Alba 30g, Radix Achyranthis Bidentatae 30g, Fructus Corni 20g, Radix Angelicae Sinensis 30g, Herba Taxilli 30g, Cortex Eucommiae 30g, Radix Astragali 50g, Radix Codonopsis 30g, Ramulus Cinnamomi 15g, Scorpio 9g, Scolopendra 5g, Fructus Jujubae 15g, Rhizoma Zingiberis Recens 10g.
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| CN1086429A (en) * | 1993-05-27 | 1994-05-11 | 高齐崧 | The compound method of hard paralysed health |
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| CN1086429A (en) * | 1993-05-27 | 1994-05-11 | 高齐崧 | The compound method of hard paralysed health |
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