CN101176805A - Intrapulmonary administration device - Google Patents

Abstract

The present invention relates to a medical device for alveolar absorption of drugs, specifically, a device for intrapulmonary drug delivery that atomizes drugs dissolved in liquid into microparticles that can reach deep into the alveoli, including a shell and a suction nozzle arranged on one side thereof, a battery, a liquid supply bottle and an atomizer are placed in the shell, wherein: one end of the liquid supply bottle is connected to the suction nozzle, and the other end is connected to the atomizer, an air inlet is opened on the shell and located above the atomizer, and an airway is opened on the outer surface of the liquid supply bottle; an action switch is installed on the shell. The present invention has uniform atomization, small atomized particles, and an average diameter of about 1 micron, which is the best technical parameter for intrapulmonary absorption; a quantitative device is provided to control the dosage. The present invention can be used for drug delivery to capillaries and alveoli.

Description

intrapulmonary drug delivery device

technical field

The invention relates to a medical device for alveolar absorption of medicine, in particular to an intrapulmonary drug delivery device that atomizes medicine dissolved in liquid into microparticles that can reach deep into alveoli.

Background technique

Most of the existing intrapulmonary drug delivery devices for medical purposes are divided into high-pressure gas tank spray devices and ultrasonic atomization devices, which are currently widely used in clinics and homes to make the alveoli absorb drugs. Although the existing intrapulmonary drug delivery device represents a technological development stage, it also has defects such as being inconvenient to carry, the atomized particles are too large, and the inhalation amount of the atomized agent is uncontrollable.

Contents of the invention

The object of the present invention is to provide an intrapulmonary drug delivery device. When using the drug delivery device, the atomized particles are small, the atomization is uniform, and the drug dosage can also be controlled.

The purpose of the present invention is achieved through the following technical solutions:

The invention includes a shell and a suction nozzle on one side thereof, and a battery, a liquid supply bottle and an atomizer are placed in the casing, wherein: one end of the liquid supply bottle communicates with the suction nozzle, and the other end is connected with the atomizer , There is an air inlet on the shell above the atomizer, and an air channel is opened on the outer surface of the liquid supply bottle; an action switch is installed on the shell.

Wherein: the atomizer is a jet heating atomizer, including a liquid supply structure and a heating body, the liquid supply structure is a porous structure or a fiber structure, one end has a jet hole, and the other end is provided with a protrusion, heating The body is placed in the liquid supply structure, and the liquid medicine in the liquid supply bottle enters the body through the liquid supply structure; the atomizer is an infiltration heating atomizer, including a liquid supply structure and a heating body, and the liquid supply structure The body is a porous body structure or a fiber structure, and one end is provided with a protrusion, and the heating body is installed at the other end, and the liquid medicine in the liquid supply bottle enters the body through the liquid supply structure; the heating body can be a metal heating wire, Conductive ceramics or PTC ceramics; there is also a gas-liquid isolation film between the air inlet and the atomizer; a quantitative device is added in the housing; a cleaning pipeline is also opened on the housing; at the air inlet of the housing An air filter is added; the liquid supply bottle is a porous body structure or a fiber structure; the action switch can be a manual switch, or an air pressure/air flow sensor, Hall device, semiconductor force-sensitive chip, semiconductor matrix thermal bridge chip Or capacitive and inductive sensors made.

Advantage of the present invention and positive effect are:

1. The invention has uniform atomization, small atomized particles, and an average diameter of about 1 micron, which is the best technical parameter for intrapulmonary absorption.

2. The present invention is provided with a dosing device, which can control the dosage.

Description of drawings

Fig. 1 is a structural representation of the present invention;

Fig. 2 is the right view of Fig. 1;

Fig. 3 is a schematic structural view of the jet heating atomizer of the present invention;

Fig. 4 is the right view of Fig. 3;

Fig. 5 is a schematic structural view of the immersion heating atomizer of the present invention;

Fig. 6 is a right side view of Fig. 5 .

Detailed ways

The present invention will be described in further detail below in conjunction with the accompanying drawings.

As shown in FIG. 1 and FIG. 2 , the present invention includes a housing 10 and a suction nozzle 2 disposed on one side thereof. The housing 10 houses a battery 1 , a liquid supply bottle 3 and an atomizer 5 . The liquid supply bottle 3 has a porous structure or a fiber structure and can be replaced; one end of the liquid supply bottle 3 communicates with the suction nozzle 2 , and the other end contacts the atomizer 5 , and an air channel 12 is opened on the outer surface of the liquid supply bottle 3 . There is an air inlet on the housing 10 above the atomizer 5 , and an air filter 9 is provided at the inlet, through which the inhaled external air enters the housing 10 after being filtered. A gas-liquid isolation membrane 8 is arranged between the air inlet and the atomizer to separate the liquid medicine and the air so that the whole device does not leak. An action switch 7 is installed on the casing 10, and it is connected in series with the battery 1 and the atomizer 5 to form a circuit. The action switch 7 can be a manual switch, or can be made with an air pressure/air flow sensor, a Hall device, a semiconductor force-sensitive chip, a semiconductor matrix thermal bridge chip, or a capacitance and inductive sensor. In order to control the dosage of administration, a certain amount device 6 can be added in the housing 10 . A cleaning pipeline 4 may also be opened on the housing 10 .

As shown in Figure 3 and Figure 4, the atomizer 5 can be a jet heating atomizer, including a liquid supply structure 101 and a heating body 102, the liquid supply structure 101 is a porous structure or a fiber structure, and a jet is opened at one end The hole 103 is provided with a protrusion 104 at the other end. The heating body 102 is accommodated in the liquid supply structure 101 , and the liquid medicine in the liquid supply bottle 3 enters the body through the liquid supply structure 101 . The heating body 102 can be a metal heating wire, a conductive ceramic or a PTC ceramic. The jet heating atomizer utilizes the inhaled airflow to conduct primary atomization in the jet hole 103, and then sprays on the heating body 102 for secondary atomization.

As shown in Figure 5 and Figure 6, the atomizer 5 can be an infiltration heating atomizer, including a liquid supply structure 201 and a heating body 202, the liquid supply structure 201 is a porous structure or a fiber structure, and one end is provided with a convex 204, the heating body 202 is installed at the other end, and the liquid medicine in the liquid supply bottle 3 enters the body through the liquid supply structure 201. The heating body 102 can be a metal heating wire, a conductive ceramic or a PTC ceramic. The immersion heating atomizer uses the heating body 202 to directly heat the liquid supply structure 201 to atomize the liquid medicine.

In the atomizers of the two structures, the protrusions 104 and 204 at one end are connected to the liquid supply bottle 3 , and the liquid medicine in the liquid supply bottle 3 gradually penetrates into the liquid supply structure. The liquid supply structure is made of foam ceramics, microporous ceramics, porous metal, stainless steel fiber felt or chemical fiber forming openings. The heating body is made of a microporous ceramic frame wound with a metal electrothermal material, or a porous body with sintered electrodes made of conductive ceramic or PTC ceramic material. The surface of the heating body is sintered into a high-temperature glaze to fix the zeolite particles, which are made of natural zeolite, artificial inorganic microporous ceramics or alumina particles.

The working principle of the present invention is: after the medicine is dissolved in propylene glycol, the medicine liquid is loaded into the replaceable liquid supply bottle 3 . Put the liquid supply bottle 3 into the casing 10, contact with the atomizer 5 and supply liquid to the atomizer. When the user inhales the suction nozzle 2, he presses the action switch 7, the circuit is connected, the battery 1 supplies power to the atomizer 5, and the heating bodies 102 and 202 start to heat. When the user breathes in, the working indicator light 11 lights up, and the outside air enters the casing 10 after being filtered by the air filter 9 , passes through the gas-liquid isolation membrane 8 , mixes with the liquid medicine, and is atomized by the atomizer 5 . The aerosol generated by the nebulizer 5 is inhaled into the lungs of the user through the airway 12 and the mouthpiece 2 . The dosing device 6 can be a microprocessor, which pre-sets the dosage for each administration, and performs atomization and quantification during the atomization process.

After use, when necessary, the user can clean the device through the cleaning pipeline 4 with water or ethanol solution.

The present invention can be used for administration in capillaries and alveoli.

Claims (11)

1. A drug delivery device in the lungs, characterized in that: it comprises a housing (10) and a suction nozzle (2) located on one side thereof, a battery (1), a liquid supply bottle are housed in the housing (10) (3) and the atomizer (5), wherein: one end of the liquid supply bottle (3) communicates with the suction nozzle (2), and the other end is connected with the atomizer (5). There is an air inlet above the device (5), and an air channel (12) is opened on the outer surface of the liquid supply bottle (3); an action switch (7) is installed on the housing (10). 2. The intrapulmonary drug delivery device according to claim 1, characterized in that: the atomizer (5) is a jet heating atomizer, comprising a liquid supply structure (101) and a heating body (102), for supplying The liquid structure (101) is a porous body structure or a fiber structure, with a jet hole (103) at one end and a protrusion (104) at the other end, and the heating body (102) is accommodated in the liquid supply structure (101) , the liquid medicine in the liquid supply bottle (3) enters its body through the liquid supply structure (101). 3. The intrapulmonary drug delivery device according to claim 2, characterized in that: the heating body (102) can be a metal heating wire, conductive ceramics or PTC ceramics. 4. The intrapulmonary drug delivery device according to claim 1, characterized in that: the atomizer (5) is an infiltration heating atomizer, comprising a liquid supply structure (201) and a heating body (202), for supplying The liquid structure (201) is a porous structure or a fiber structure, one end of which is provided with a protrusion (204), the heating body (202) is installed at the other end, and the liquid medicine in the liquid supply bottle (3) penetrates the liquid supply structure (201) into its body. 5. The intrapulmonary drug delivery device according to claim 4, characterized in that: the heating body (102) can be a metal heating wire, conductive ceramics or PTC ceramics. 6. The intrapulmonary drug delivery device according to claim 1, characterized in that: an air-liquid isolation membrane (8) is also provided between the air inlet and the nebulizer (5). 7. The intrapulmonary drug delivery device according to claim 1, characterized in that a dosing device (6) is added in the housing (10). 8. The intrapulmonary drug delivery device according to claim 1, characterized in that: the housing (10) is also provided with a cleaning pipeline (4). 9. The intrapulmonary drug delivery device according to claim 1, characterized in that an air filter (9) is added at the air inlet of the casing (10). 10. The intrapulmonary drug delivery device according to claim 1, characterized in that: the liquid supply bottle (3) has a porous structure or a fiber structure. 11. The intrapulmonary drug delivery device according to claim 1, characterized in that: the action switch (7) can be a manual switch, or an air pressure/airflow sensor, Hall device, semiconductor force-sensitive chip, semiconductor matrix thermoelectric Bridge chips or capacitive and inductive sensors are made.

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