CN101168029B - 舒肝理气解毒胶囊的制作方法 - Google Patents
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Abstract
舒肝理气解毒胶囊的制作方法，它是一种用中草药制备的治疗急、慢性肝炎口服的胶囊。制作该胶囊的原料为：当归、白芍、柴胡、郁金、五味子、黄芩、龙胆草、虎杖、茵陈、茯苓、草河车、山药、党参、陈皮、木香、砂仁、板蓝根、败酱草、川楝子、二花、蒲公英、甘草，将上述中草药按一定的重量配比，烘干、粉碎、过筛分装入无菌胶囊。本疗效显著，据对数百例急、慢性肝炎患者的观察；其中基本治愈(标准：临床症状消失，HBV-DNV检测阴性，肝功能正常，随访10年以上未见复发)不低于86％。
Description
一、技术领域
本发明是一种用中草药制备一种治疗急、慢性肝炎口服胶囊的方法。
二、背景技术
据有关资料显示，有将近十分之一的人患有肝病，已成为严重威胁人类健康的重要杀手，人们之所以谈肝色变，是因为肝病有急强的传染性，急性肝炎或慢性病毒携带者急易转成慢性肝炎，且肝炎病毒易于潜伏，常可携带终身。急、慢性肝炎主要为为疫毒之邪，首犯肌肤，入于血分，深藏于肝。肝为五脏之一，脏本藏精气而不泻，若邪伏于肝，则难自净，是以难治。乙肝固为疫毒之邪，但发于外则多表现为湿热，故又称之为湿热疫毒，与不同者，实在于毒之性质区别，故取一般清热利湿之剂治之，或能取效，但邪留体内，故迭复发，迁延而成慢性。目前的患者有很大一部分得不到较正规系统的治疗，特别是缺医少药的贫困地区更是如此，给患者及其家庭造成精神和心理上的极大损害。西药采用的一些治疗方法也得不到根治，易产生药物依赖。
三、发明内容
本发明的目的是全部采用中草药原料制作一种可治疗急、慢性肝炎的口服胶囊。
制作该胶囊的原料为：当归、白芍、柴胡、郁金、五味子、黄芩、龙胆草、虎杖、茵陈、茯苓、草河车、山药、党参、陈皮、木香、砂仁、板蓝根、败酱草、川楝子、二花、蒲公英、甘草，其重量配比依次为10∶10-30∶12-30∶8-20∶12-30∶10-30∶12-50∶20-60∶50-80∶10-30∶20-30∶10-30∶12-50∶8-16∶8-16∶6-10∶20-120∶20-80∶8-30∶12-50∶12-70∶6-12。
制作方法为：将所有中草药原料在60-80℃烘箱内烘干后，经粉碎、混合过120目筛，以0.5克装入无菌胶囊。
服用方法：用温开水送服，每次5粒，每日3次。1个月为一疗程；服药期间禁食生冷，忌油腻辛辣刺激物。调整患者的饮食，宜少食多餐，予有营养易于消化的食物。
适应症：急、慢性乙型肝炎。活动期，表现为谷丙转氨酶显著升高。
其药理为：按地(肝)为将军之官，主舒泄，性喜调达而恶抑郁，为藏血之脏，本阴而用阳，是人体气机运行畅达的保证，若情志不遂，肝木失于条达，肝体失于矛格以致肝气横逆，胁痛等症随之而起。且肝木为病，易于横侮脾土，脾胃居于中焦，为气机升降之枢纽，若中土受损，人体气机之升降逆乱，诸症峰起。故本方使用舒肝理气解郁之品，意即顺其条达之性，发其郁遏之气，正合《内经》“木郁达之”之旨，又伍健脾助运之味，实土以御木侮。且肝气条，则肝血不足，所以肝郁易致血亏，虚则外邪侵入，恋于肝内，故更佐清肝解毒之剂，补肝体而和肝用，以消除外来之邪毒，如是则体用兼顾，肝脾并治共奏祛邪扶正之效。方中柴胡、黄芩、郁金舒肝解郁；当归、白芍、五味子养血敛阴柔肝；茯苓、甘草、山药、党参、陈皮、木香、砂仁健脾行气开胃；板蓝根、败酱草、龙胆草、虎杖清热解毒，抗菌谱广，又兼有抗病毒作用，尤其对肝炎病毒有较强的杀灭作用，并能促进肝细胞再生，防止肝细胞变性；二花、公英、草河车清热解毒，对多种细菌、病毒有较强的杀灭作用；茵陈、川楝子清热利湿，舒肝利胆，对多种病毒，细菌有较强的抑制作用，为肝胆疾患所常用。以上诸药相伍，即可以通过清热解毒杀灭病菌等作用以祛邪，又可通过舒肝健脾而调动机体抗病力以扶正，是治疗急、慢性迁延肝炎的理想方剂，用药之灵验，临床可连续服2-4个疗程，无不良反应。对于肝功能不正常患者，不管有无临床症状，均有疗效。
本疗效显著，据对968例急、慢性肝炎患者的观察；其中基本治愈(标准：临床症状消失，HBV-DNV检测阴性，肝功能正常，随访10年以上未见复发)不低于86％：明显好转(标准：临床症状基本消失，肝功能检测偶有一项或两项不正常)不低于11％；无效3例。
四、具体实施方式
例1：首先取当归10克，然后取白芍、黄芩、茯苓、山药各10克，柴胡、五味子各12克，郁金8克，龙胆草、党参、二花各12克，虎杖20克，茵陈50克，草河车20克，陈皮、木香各8克，砂仁6克，板蓝根20克，败酱草20克，川楝子8克，蒲公英12克，甘草6克，将上述原料冼净去杂在60-80℃烘箱内烘干后，经粉碎混合过120目筛，以每粒0.5克装入胶囊，经无毒处理后即可服用；
例2：首先取当归10克，然后取白芍、黄芩、茯苓、山药各20克，柴胡、五味子各20克，郁金10克，龙胆草、党参、二花各30克，虎杖40克，茵陈65克，草河车25克，陈皮、木香各12克，砂仁8克，板蓝根70克，败酱草50克，川楝子20克，蒲公英40克，甘草9克，将上述原料冼净去杂后放入60-80℃烘箱内烘干后，经粉碎混合过120目筛，以每粒0.5克装入胶囊，经无毒处理后即可服用；
例3：首先取当归10克，然后取白芍、黄芩、茯苓、山药各30克，柴胡、五味子各30克，郁金20克，龙胆草、党参、二花各50克，虎杖60克，茵陈80克，草河车30克，陈皮、木香各16克，砂仁10克，板蓝根120克，败酱草80克，川楝子30克，蒲公英70克，甘草12克，将上述原料冼净去杂后放入60-80℃烘箱内烘干后，经粉碎混合过120目筛，以每粒0.5克装入胶囊，经无毒处理后即可服用。
Claims (1)
1.舒肝理气解毒胶囊的制作方法，其特征在于：
(1)制作该胶囊的原料为：当归、白芍、柴胡、郁金、五味子、黄芩、龙胆草、虎杖、茵陈、茯苓、草河车、山药、党参、陈皮、木香、砂仁、板蓝根、败酱草、川楝子、二花、蒲公英、甘草，其重量配比依次为10∶10-30∶12-30∶8-20∶12-30∶10-30∶12-50∶20-60∶50-80∶10-30∶20-30∶10-30∶12-50∶8-16∶8-16∶6-10∶20-120∶20-80∶8-30∶12-50∶12-70∶6-12；
(2)制作方法为：将所有中草药原料在60-80℃烘箱内烘干后，经粉碎、混合过120目筛，以0.5克装入无菌胶囊。
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| CN101889664B (zh) * | 2010-04-22 | 2012-07-04 | 广东海洋大学 | 一种预防罗非鱼脂肪肝病的中草药添加剂 |
| CN102441147A (zh) * | 2011-12-20 | 2012-05-09 | 北京天科仁祥医药科技有限公司 | 一种治疗慢性肝炎的中药复方制剂 |
| CN102836228B (zh) * | 2012-10-10 | 2014-06-25 | 滨州医学院附属医院 | 一种治疗结膜炎的中药组合物及其制备方法和应用 |
| CN103463543B (zh) * | 2013-08-19 | 2015-04-29 | 赵四秧 | 医用雷火神灸 |
| CN104189789A (zh) * | 2014-09-28 | 2014-12-10 | 袁国防 | 一种治疗急性传染性黄疸型肝炎的中药组合物 |
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| Title |
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| 韦麟, 潘炳堂, 黄礼周, 甘荣军.慢性乙型肝炎中医治疗近况.甘肃中医20 5.2007,20(5),90-92. |
| 韦麟, 潘炳堂, 黄礼周, 甘荣军.慢性乙型肝炎中医治疗近况.甘肃中医20 5.2007,20(5),90-92. * |
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