CN101168007A - Medicine for treating cerebral palsy diseases and its preparing process - Google Patents
Medicine for treating cerebral palsy diseases and its preparing process Download PDFInfo
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- CN101168007A CN101168007A CNA2007101396966A CN200710139696A CN101168007A CN 101168007 A CN101168007 A CN 101168007A CN A2007101396966 A CNA2007101396966 A CN A2007101396966A CN 200710139696 A CN200710139696 A CN 200710139696A CN 101168007 A CN101168007 A CN 101168007A
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- cerebral palsy
- fermentation liquid
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- 239000003814 drug Substances 0.000 title claims abstract description 28
- 206010008129 cerebral palsy Diseases 0.000 title claims abstract description 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims abstract description 13
- 229940079593 drug Drugs 0.000 title abstract 2
- 230000000694 effects Effects 0.000 claims abstract description 15
- 239000002775 capsule Substances 0.000 claims abstract description 7
- 238000000855 fermentation Methods 0.000 claims description 16
- 239000007788 liquid Substances 0.000 claims description 16
- 230000004151 fermentation Effects 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 9
- 230000000243 photosynthetic effect Effects 0.000 claims description 8
- 241000255791 Bombyx Species 0.000 claims description 5
- 239000009636 Huang Qi Substances 0.000 claims description 5
- 206010033799 Paralysis Diseases 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 5
- 241000894006 Bacteria Species 0.000 claims description 4
- 239000012141 concentrate Substances 0.000 claims description 4
- 150000002333 glycines Chemical class 0.000 claims description 4
- 239000008187 granular material Substances 0.000 claims description 4
- 230000001590 oxidative effect Effects 0.000 claims description 4
- 210000000582 semen Anatomy 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 2
- 230000002490 cerebral effect Effects 0.000 claims 3
- 230000001148 spastic effect Effects 0.000 claims 3
- 208000014644 Brain disease Diseases 0.000 abstract description 4
- 230000003925 brain function Effects 0.000 abstract description 3
- 201000010099 disease Diseases 0.000 abstract description 3
- 230000036039 immunity Effects 0.000 abstract description 3
- 239000002994 raw material Substances 0.000 abstract description 3
- 230000006870 function Effects 0.000 abstract description 2
- 241001061264 Astragalus Species 0.000 abstract 1
- 235000010110 Astragalus glycyphyllos Nutrition 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 241000255789 Bombyx mori Species 0.000 abstract 1
- 241000830535 Ligustrum lucidum Species 0.000 abstract 1
- 241000237502 Ostreidae Species 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 241000157352 Uncaria Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 238000005538 encapsulation Methods 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 235000020636 oyster Nutrition 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 description 8
- 210000004556 brain Anatomy 0.000 description 6
- 210000000952 spleen Anatomy 0.000 description 6
- 230000009471 action Effects 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 230000007812 deficiency Effects 0.000 description 4
- 210000004185 liver Anatomy 0.000 description 4
- 230000008859 change Effects 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 239000002552 dosage form Substances 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 238000000554 physical therapy Methods 0.000 description 2
- 208000037920 primary disease Diseases 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 238000012549 training Methods 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 241000931705 Cicada Species 0.000 description 1
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 208000014094 Dystonic disease Diseases 0.000 description 1
- 208000032274 Encephalopathy Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000003190 augmentative effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000013256 coordination polymer Substances 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 208000010118 dystonia Diseases 0.000 description 1
- 206010014599 encephalitis Diseases 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 230000008111 motor development Effects 0.000 description 1
- 208000037922 refractory disease Diseases 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940126672 traditional medicines Drugs 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a Chinese patent drug for treating a disease of cerebral palsy. The raw materials of the invention comprise milk vetch root, atractylodes rhizome, glossy privet fruit, root of rehmannia, hooked uncaria, stiff silkworm, oyster and the like, which are made into a capsule after decoction, concentration and desiccation and further encapsulation. The invention has the advantages of enhancing immunity, improving self functions, and having a better effect to improve brain function and a prominent effect to treat the brain diseases.
Description
Technical field
The present invention relates to a kind of medicine, be specifically related to a kind of preparation method for the treatment of Chinese medicine preparation and this medicine of cerebral palsy.
Background technology
Cerebral palsy of children is a kind of worldwide refractory disease, and its domestic sickness rate accounts for 2.7-5 ‰, gives family, and society causes serious burden, and western medical treatment is dissatisfied again, therefore, can bring into play the effect of Chinese medicine.The traditional Chinese medical science thinks that the brain disease is that brains lose to be supported, the natural endowment deficiency, and kidney is given birth to marrow and is supported brain, the hepatic and renal YIN deficiency, the marrow life of becoming homeless, brain is become homeless foster, causes immunity degradation.Primary disease mostly is deficiency syndrome or simulataneous insufficiency and excessive, not enough and the person that causes the caused by liver and kidney deficiency of natural endowment is promptly arranged, having lose the day after tomorrow again supports, insufficiency of the spleenly can not change angry blood person, clinical many with the kidney invigorating nourishing the liver brain-strengthening, life essence-filling, marrow-benefitting has the flourish brain of spleen benefiting and replenishing qi and blood again, so it is main that the base therapy rule of primary disease with strengthening the body resistance, is augmented the spleen kidney.At present, the medicine that is used for the treatment of children's's cerebral palsy is symptomatic treatment mostly, and curative effect is all not good enough.
Summary of the invention
The object of the invention provides a kind of brain disease that is suitable for treating, and treating both the principal and secondary aspects of a disease to improving immunity, strengthens self function especially, improves the Chinese Traditional Medicines that brain function has better effects, and the preparation method that this medicine is provided.
Solution of the present invention is based on tcm theory: nourishing kidney-yin, marrow are become homeless and given birth to, brain is become homeless foster, insufficiency of the spleenly can not change angry blood person, and treatment is with the kidney invigorating nourishing the liver, and brain-strengthening, life essence-filling, marrow-benefitting, invigorating the spleen and benefiting QI, beneficial brain nourishes blood.
A kind of medicine for the treatment of cerebral palsy diseases of the present invention is the medicament of being made by the following materials based on weight medicine:
Radix Astragali 10-20 Fructus Alpiniae Oxyphyllae 6-12 Fructus Ligustri Lucidi 3-6 Radix Rehmanniae 6-12
Ramulus Uncariae cum Uncis 9-18 Bombyx Batryticatus 6-12 Radix Salviae Miltiorrhizae 6-12 Periostracum Cicadae 9-18
Radix Glycyrrhizae 3-6 Radix Polygalae 3-6 Rhizoma Atractylodis Macrocephalae 6-12 Concha Ostreae 3-6
Rhizoma Anemarrhenae 6-12.
Above-mentioned each component can be made said dosage form on any pharmaceutics, and as decoction, tablet, powder, capsule, electuary etc., the preferred dosage form of the present invention is a capsule.
Above-mentioned a kind of preparation method for the treatment of the medicine of cerebral palsy is: close with Semen Glycines and Chinese medicine earlier and fry in shallow oil into decocting liquid, the fermentation liquid behind photosynthetic oxidative fermentation adds Naco
3, be deployed into pH value and be 3 fermentation liquid, add 2%Seo again
2Fermentation liquid after the photosynthetic bacteria effect, concentrate 8 times and become concentrated solutions, dry back becomes dry powder, makes the capsule product after the granulate classification.
The present invention is a kind of to be treated in the medicine of cerebral palsy diseases: the Radix Astragali, the Rhizoma Atractylodis Macrocephalae are the medicine of invigorating the spleen and replenishing QI, and Fructus Ligustri Lucidi, Radix Rehmanniae are in the moon of the kidney invigorating, Fructus Alpiniae Oxyphyllae is reinforce spleen and kidney together then, thereby mend congenital kidney and the day after tomorrow spleen deficiency, Ramulus Uncariae Cum Uncis, Bombyx Batryticatus, Concha Ostreae have the suppressing the hyperactive liver to relieve the wind syndrome effect, and Periostracum Cicadae, the Rhizoma Anemarrhenae can rush down wind heat clearly, and Radix Salviae Miltiorrhizae always plays activating blood circulation to dissipate blood stasis, microcirculation improvement, the Radix Polygalae mind tranquilizing and the heart calming plays the effect that improves brain function jointly.
Clinical observation: 1. 2. age＜14 year old of the standard of formulating by national children's's cerebral palsy forum in 1988.3. adopt Gesell to grow diagnosis scale (Beijing child health care is revised) before and after the treatment and test, and calculate action (comprising thick action, fine movement) and grow the merchant.Evaluation criteria: produce effects: posture, action and dystonia obtain substantive progress, and the merchant is grown in action to be increased above 100%; Effectively: symptom, sign alleviate, and ordinary circumstance takes a turn for the better, and action is grown the merchant and increased to 10～100%; Invalid: symptom, sign no change, growth merchant increase are lower than 10%.Exclusion standard: 1. a course of treatment is discontented with in treatment.2. the paralysis due to the paralysis of the maincenter due to PD disease, and various encephalitis, the encephalopathy.3. normal children's's one property crossed Motor development falls behind.Screening 126 routine patients with cerebral palsy carry out the random packet treatment from the 0-14 of my institute's diagnosis and treatment in 2005 to 2006 year CP children, A organizes 63 examples, B organizes 63 examples, A group channel, rehabilitation training, physical therapy Comprehensive Treatment, B channel, rehabilitation training, physical therapy Comprehensive Treatment add oral said preparation, after 3 courses of treatment, grow the evaluation of diagnosis scale through Gesell, the result shows: it is effective that A organizes 33 people, 21 people's produce effects, 9 people are invalid, total effective rate 85.7%, obvious effective rate 33.3%, it is effective that B organizes 28 people, 32 people's produce effects, and 3 people are invalid, total effective rate 95.2%, obvious effective rate 50.7%.
| Classification | Effectively (example) | Produce effects (example) | Invalid (example) | Total effective rate | Obvious effective rate |
| The A group | 33 | 21 | 9 | 85.7％ | 33.3％ |
| The B group | 28 | 32 | 3 | 95.2％ | 50.7％ |
The specific embodiment
Embodiment 1:
A kind of medicine for the treatment of cerebral palsy diseases takes by weighing raw material by following weight (part) proportioning:
Radix Astragali 10g Fructus Alpiniae Oxyphyllae 12g Fructus Ligustri Lucidi 6g Radix Rehmanniae 12g
Ramulus Uncariae cum Uncis 18g Bombyx Batryticatus 12g Radix Salviae Miltiorrhizae 12 Periostracum Cicadaes 18
Radix Glycyrrhizae 6g Radix Polygalae 6g Rhizoma Atractylodis Macrocephalae 12g Concha Ostreae 6g
Rhizoma Anemarrhenae 12g.
Concrete preparation method:
Close with Semen Glycines and Chinese medicine earlier and fry in shallow oil into decocting liquid, the fermentation liquid behind photosynthetic oxidative fermentation adds Naco
3, be deployed into pH value and be 3 fermentation liquid, add 2%Seo again
2Fermentation liquid after the photosynthetic bacteria effect, concentrate 8 times and become concentrated solutions, dry back becomes dry powder, makes the capsule product after the granulate classification.
Embodiment 2:
A kind of medicine for the treatment of cerebral palsy diseases takes by weighing raw material by following weight (part) proportioning:
Radix Astragali 40g Fructus Alpiniae Oxyphyllae 24g Fructus Ligustri Lucidi 12g Radix Rehmanniae 24g
Ramulus Uncariae cum Uncis 36g Bombyx Batryticatus 24g Radix Salviae Miltiorrhizae 24g Periostracum Cicadae 36g
Radix Glycyrrhizae 12g Radix Polygalae 12g Rhizoma Atractylodis Macrocephalae 24g Concha Ostreae 12g
Rhizoma Anemarrhenae 24g.
Concrete preparation method:
Close with Semen Glycines and Chinese medicine earlier and fry in shallow oil into decocting liquid, the fermentation liquid behind photosynthetic oxidative fermentation adds Naco
3, be deployed into pH value and be 3 fermentation liquid, add 2%Seo again
2Fermentation liquid after the photosynthetic bacteria effect, concentrate 8 times and become concentrated solutions, the electuary product is made after becoming the classification of dry powder granulate in dry back.
Claims (4)
1. medicine for the treatment of cerebral palsy diseases is characterized in that: the medicament of being made by the following materials based on weight medicine:
Radix Astragali 10-20 Fructus Alpiniae Oxyphyllae 6-12 Fructus Ligustri Lucidi 3-6 Radix Rehmanniae 6-12
Ramulus Uncariae cum Uncis 9-18 Bombyx Batryticatus 6-12 Radix Salviae Miltiorrhizae 6-12 Periostracum Cicadae 9-18
Radix Glycyrrhizae 3-6 Radix Polygalae 3-6 Rhizoma Atractylodis Macrocephalae 6-12 Concha Ostreae 3-6
Rhizoma Anemarrhenae 6-12.
2. the medicine of treatment spastic cerebral paralysis disease according to claim 1 is characterized in that: described medicament is a capsule.
3. the preparation method of the described treatment spastic cerebral paralysis disease of claim 2 is characterized in that: close with Semen Glycines and Chinese medicine earlier and fry in shallow oil into decocting liquid, the fermentation liquid behind photosynthetic oxidative fermentation, interpolation Naco
3, be deployed into pH value and be 3 fermentation liquid, add 2%Seo again
2Fermentation liquid after the photosynthetic bacteria effect, concentrate 8 times and become concentrated solutions, dry back becomes dry powder, makes the capsule product after the granulate classification.
4. the medicine of treatment spastic cerebral paralysis disease according to claim 1 is characterized in that: described medicament is an electuary.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101396966A CN101168007A (en) | 2007-10-31 | 2007-10-31 | Medicine for treating cerebral palsy diseases and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101396966A CN101168007A (en) | 2007-10-31 | 2007-10-31 | Medicine for treating cerebral palsy diseases and its preparing process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101168007A true CN101168007A (en) | 2008-04-30 |
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ID=39388858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101396966A Pending CN101168007A (en) | 2007-10-31 | 2007-10-31 | Medicine for treating cerebral palsy diseases and its preparing process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101168007A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579974A (en) * | 2012-02-15 | 2012-07-18 | 高玉元 | Chinese medicinal wearing bag for treating cerebral palsy |
| CN104906518A (en) * | 2015-07-01 | 2015-09-16 | 李晓莉 | Medicine for treating child cerebral palsy |
-
2007
- 2007-10-31 CN CNA2007101396966A patent/CN101168007A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579974A (en) * | 2012-02-15 | 2012-07-18 | 高玉元 | Chinese medicinal wearing bag for treating cerebral palsy |
| CN102579974B (en) * | 2012-02-15 | 2013-06-12 | 高玉元 | Chinese medicinal wearing bag for treating cerebral palsy |
| CN104906518A (en) * | 2015-07-01 | 2015-09-16 | 李晓莉 | Medicine for treating child cerebral palsy |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20080430 |