CN101167647A - Dental pulp vitality fluorescence detection device and detection method - Google Patents
Dental pulp vitality fluorescence detection device and detection method Download PDFInfo
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Abstract
本发明提供了一种牙髓活力荧光检测装置和方法,采用荧光进行检测,即调制后的激发光经滤光器后,由发射光纤传输经探头窗口照射到被检牙表面,激励牙齿产生荧光辐射,又被探头窗口中的接收光纤接收并传输,经接收滤光片传送到微光检测单元,进而进入数据处理和控制电路统一控制和处理。本发明解决了无痛苦检测牙病尤其是快速检测牙髓活力、牙脱矿、龋坏牙本质综合性检测的专业难题,检测准确,能直接显示相对应数据。可选择单点检测和多点检测,具有检测的灵活性,检测过程可以剔除操作错误。快速,直观,准确,检测范围大,结构简单。可以用于口腔医院、牙科诊所等需要对牙病进行检测的场所。
The invention provides a fluorescence detection device and method for dental pulp vitality. Fluorescence is used for detection, that is, after the modulated excitation light is passed through an optical filter, it is transmitted by an emission optical fiber and irradiated to the surface of the tooth to be inspected through the probe window to stimulate the tooth to generate fluorescence. The radiation is received and transmitted by the receiving optical fiber in the probe window, and sent to the low-light detection unit through the receiving filter, and then enters the data processing and control circuit for unified control and processing. The invention solves the professional problem of painless detection of dental diseases, especially rapid detection of dental pulp vitality, tooth demineralization, and carious dentin comprehensive detection. The detection is accurate and the corresponding data can be directly displayed. Single-point detection and multi-point detection can be selected, with the flexibility of detection, and the detection process can eliminate operational errors. Fast, intuitive, accurate, large detection range, simple structure. It can be used in dental hospitals, dental clinics and other places that need to detect dental diseases.
Description
技术领域technical field
本发明装置属于医疗检测设备技术领域,是一种口腔牙齿的检测设备,具体讲就是一种检测牙髓活力的荧光检测装置及检测方法。The device of the invention belongs to the technical field of medical detection equipment, and is a detection device for oral cavity teeth, specifically a fluorescence detection device and a detection method for detecting pulp vitality.
背景技术Background technique
牙髓活力测试是牙体牙髓病诊治中的重要环节,传统的检测手段如牙髓电活力测试和温度试验,表现的是牙髓感觉神经的反映,因有一定的主观性而不准确,同时这些检测手段的刺激会增加患者的痛苦。目前国内对牙髓活力的检测还是普遍使用电活力测试仪。它是用从低到高的梯度电压来刺激患者牙齿,当患者感到疼痛时,记录电压的高低,判断牙齿的活力。痛感电压越低,说明牙髓越有活力,电压越高,说明牙髓的活力越低,甚至没有活力。由于每个人对相同电压的敏感程度差别很大,这样就造成人为的主观误差。Pulp vitality test is an important link in the diagnosis and treatment of endodontic diseases. Traditional detection methods, such as pulp electrical vitality test and temperature test, show the reflection of the sensory nerve in the pulp, which is inaccurate due to certain subjectivity. Simultaneously, the stimulation of these detection means can increase the misery of the patient. At present, electric vitality tester is widely used in the detection of pulp vitality in China. It uses a gradient voltage from low to high to stimulate the patient's teeth. When the patient feels pain, the voltage level is recorded to judge the tooth's vitality. The lower the pain-sensing voltage, the more active the dental pulp is, and the higher the voltage, the lower the vitality of the dental pulp, or even no vitality. Because each person's sensitivity to the same voltage varies greatly, this causes human-made subjective errors.
以光学原理而设计的牙病检测装置,具有无刺激,非侵入性,方便、实时、客观、对病人无痛苦、无伤害等优点,正在越来越受到重视和发展。Dental disease detection devices designed on the basis of optical principles have the advantages of non-stimulation, non-invasiveness, convenience, real-time, objective, no pain and no harm to patients, and are receiving more and more attention and development.
目前采用荧光技术进行牙髓活力的检测是一个新的研究方向。At present, it is a new research direction to use fluorescence technology to detect pulp vitality.
中国专利公开号为:CN1309545A的“用于牙菌斑检测的带有荧光装置的牙刷”,是一种具有检查牙齿表面生物沉积即检测牙菌斑功能的牙刷,可插入口中使用,给出牙齿表面使用前后是否有牙菌斑或牙菌斑被清除的提示。是一种口腔清洁保健装置,没有对牙病检测的功能,更不能对牙髓活力的状况进行检测。The Chinese Patent Publication No. is: CN1309545A "Toothbrush with Fluorescent Device for Detection of Dental Plaque", which is a toothbrush with the function of inspecting the biodeposition on the tooth surface, that is, detecting dental plaque. It can be inserted into the mouth and used to give teeth Whether there is plaque on the surface or an indication that the plaque has been removed before and after the surface is used. It is a device for cleaning and health care of the oral cavity. It has no function of detecting dental diseases, let alone detecting the vitality of the dental pulp.
中国专利公开号为:CN1703162A的“用于检测龋齿的系统和方法”,同样不能直接给出牙髓活力的数据显示,不能与高速的信息处理系统进行数据和图象存储以及传输或通讯。The Chinese Patent Publication No.: CN1703162A "System and Method for Detecting Dental Caries" also cannot directly provide data display of pulp vitality, and cannot store, transmit or communicate data and images with a high-speed information processing system.
以上专利虽然采用了荧光技术,但它们有的只能用于检测龋齿,有的只能检测牙齿的干净与否,均不能检测更多的牙病项目,更不能检测牙髓活力状态。当然也不能与高速的信息处理系统进行数据和图象存储以及传输或通讯。Although the above patents use fluorescence technology, some of them can only be used to detect dental caries, and some can only detect whether the teeth are clean or not, and they cannot detect more dental disease items, let alone detect the state of dental pulp vitality. Certainly also can not carry out data and image storage and transmission or communication with high-speed information processing system.
本发明项目组对国内外专利文献和公开发表的期刊论文检索,再尚未发现与本发明密切相关和一样的报道或文献。The project team of the present invention searched domestic and foreign patent documents and published periodical papers, and found no reports or documents closely related to the present invention.
发明内容Contents of the invention
本发明的目的是克服上述技术和仪器存在的缺点及不足,提供一种主要检测牙髓活力,还可检测获得牙齿脱矿、龋坏牙本质和牙菌斑的相关数据,可以不受环境中各种杂光干扰,采用体积小的探头,检测范围大,对患者检查无侵害,无刺激、无痛苦,对牙齿的整个外露部分,包括咬合面均可进行检测,检测准确,实时显示检查结果,其检测数据可以进行数据和图象处理以及存储、传输或通讯的牙髓活力检测装置及检测方法。The purpose of the present invention is to overcome the shortcomings and deficiencies of the above-mentioned technologies and instruments, and provide a method that mainly detects the vitality of the dental pulp, and can also detect and obtain relevant data on tooth demineralization, carious dentin and dental plaque, which can not be affected by the environment. All kinds of stray light interference, using a small probe with a large detection range, no harm to the patient, no stimulation, no pain, the entire exposed part of the tooth, including the occlusal surface, can be detected, the detection is accurate, and the inspection result is displayed in real time A device and method for detecting pulp vitality that can be processed, stored, transmitted or communicated for data and image processing.
下面对本发明进行详细说明:The present invention is described in detail below:
本发明是一种牙髓活力荧光检测装置和方法,其实现在于:检测装置包括有光学处理单元,将接收到被检测牙齿的荧光辐射与健康牙齿的荧光辐射进行比较的比较装置和用于传导光的光纤束。光学处理单元包括激发荧光的发射光路、接收牙齿表面荧光辐射光的接收光路,发射光路中产生激励光的光源是调制光源,其特征在于:检测装置还包括有检测仪,与检测仪相连接的光纤束端头分为两束,一束为激发光纤,其端面对准发射光路中的滤光器,另一束为接收光纤,其端面对准荧光接收光路中的滤光器,光纤束的另一端与探头连接,光纤束的直径在1.6mm-2.5mm之间,发射光路的发光器件选择紫光LED,发射光路上滤光器通过的激励光线光谱范围是410nm-430nm,接收光路上的滤光器可通过的荧光光谱范围是:440nm-800nm,在光纤束以及探头中发射光纤与接收光纤的数量的比例为2/5比3/5,探头的探测端口安装带有窗口的探头帽,检测仪的面板上设有液晶显示屏、功能开关和小型键盘,检测仪内安装有数据处理与控制电路和光学处理单元。The present invention is a fluorescence detection device and method for pulp vitality, which is realized in that the detection device includes an optical processing unit, a comparison device for comparing the fluorescence radiation received from the detected tooth with the fluorescence radiation of healthy teeth, and a conducting Fiber optic bundle of light. The optical processing unit includes an emitting optical path for exciting fluorescence, and a receiving optical path for receiving fluorescence radiation light on the tooth surface. The light source for generating excitation light in the emitting optical path is a modulated light source. It is characterized in that: the detection device also includes a detector connected to the detector. The end of the fiber bundle is divided into two bundles, one is the excitation fiber, and its end face is aligned with the optical filter in the emission optical path, and the other is the receiving optical fiber, and its end is aligned with the optical filter in the fluorescence receiving optical path. The other end of the bundle is connected to the probe. The diameter of the fiber bundle is between 1.6mm-2.5mm. The light-emitting device of the emitting light path is purple LED. The fluorescent spectrum range that the optical filter can pass is: 440nm-800nm, the ratio of the number of emitting fibers to receiving fibers in the fiber bundle and probe is 2/5 to 3/5, and the detection port of the probe is equipped with a probe with a window Cap, the panel of the tester is equipped with a liquid crystal display, a function switch and a small keyboard, and a data processing and control circuit and an optical processing unit are installed in the tester.
本发明针对牙髓活力检测难度大的实际问题,利用牙齿能够激发荧光的自然特性,采用调制的紫光LED为激励光源照射被测牙齿,调制光源使得牙齿激发出来的荧光也被调制,方便接收,在自然光环境下应用能避免杂散光的干扰。光的发射和接收均通过专用的探头对准牙齿的同一部位,所获取的荧光辐射强度与事先检测并存入检测仪内健康牙齿或牙齿健康部分的参考值作比较,从而得到所检测牙齿的数据或牙齿病变的数据,具有定量的比较和分析,进而得到被测牙齿的牙髓活力状况或龋齿、牙脱矿等病变情况。探头体积小,对于口腔深处的智齿以及畸形牙也能检测,对牙齿的外露表面包括侧面和咬合面均可进行检测,对患者检测无侵害,无刺激、无痛苦。Aiming at the practical problem that the detection of pulp vitality is difficult, the present invention utilizes the natural characteristic that the tooth can excite fluorescence, adopts the modulated purple light LED as the exciting light source to irradiate the tooth to be tested, modulates the light source so that the fluorescence excited by the tooth is also modulated, and is convenient for receiving. Application in natural light environment can avoid the interference of stray light. The emission and reception of light are aimed at the same part of the tooth through a special probe, and the obtained fluorescence radiation intensity is compared with the reference value of the healthy tooth or the healthy part of the tooth detected in advance and stored in the detector, so as to obtain the detected tooth. Data or data of tooth lesions can be quantitatively compared and analyzed, and then the pulp vitality of the tested teeth or the lesions such as dental caries and tooth demineralization can be obtained. The probe is small in size, and can also detect wisdom teeth and deformed teeth deep in the oral cavity. It can also detect exposed surfaces of teeth, including side surfaces and occlusal surfaces. It is non-invasive, non-stimulating, and pain-free for patients.
本发明选择的激发光的波长范围在410nm-430nm,这是在不损害人体健康的情况下,能够激励牙齿产生更多的荧光辐射的波长范围,同时也能增加检测灵敏度与检测准确性。本发明设定了较大的获取荧光辐射的接收范围,以适应检测牙髓活力状况或龋齿、牙脱矿等病变情况。The wavelength range of the excitation light selected in the present invention is 410nm-430nm, which is the wavelength range that can stimulate teeth to generate more fluorescent radiation without damaging human health, and can also increase detection sensitivity and detection accuracy. The present invention sets a relatively large receiving range for obtaining fluorescent radiation, so as to be suitable for detecting dental pulp vitality or dental caries, tooth demineralization and other lesion conditions.
本发明采用的探头体积小,便于在有限的口腔空间操作。在光纤束中发射光纤与接收光纤的数量的比例为2/5比3/5,这种优化比例可满足对各种牙齿的检测。探头的探测端口安装有带有窗口的探头帽,保证光纤对于荧光辐射的接收处于最佳位置上,也便于清洁和保护光纤正常工作。The volume of the probe adopted in the present invention is small, and it is convenient to operate in a limited oral cavity space. The ratio of the number of transmitting optical fibers to receiving optical fibers in the optical fiber bundle is 2/5 to 3/5, and this optimized ratio can meet the detection of various teeth. The detection port of the probe is equipped with a probe cap with a window to ensure that the optical fiber is in the best position for receiving fluorescent radiation, and it is also convenient for cleaning and protecting the normal operation of the optical fiber.
以光学原理而设计的牙髓活力检测装置,属于非接触检测,具有无刺激和非侵入性,又能满足方便的检测要求。对牙齿检测的同时检测仪显示与牙病相关的对应数据,使得医生可以从速诊断牙齿病变的所在以及严重程度。The pulp vitality detection device designed on the principle of optics belongs to non-contact detection, which is non-stimulating and non-invasive, and can meet the convenient detection requirements. While testing the teeth, the detector displays corresponding data related to dental diseases, so that doctors can quickly diagnose the location and severity of dental lesions.
本发明的实现还在于:检测仪内安装的数据处理和控制电路包括有微控制器、键盘及显示电路、通讯接口电路、A/D转换电路、微光检测单元、光源调制驱动电路和LED发光单元,微控制器与其他组成电路均有电信号连接,检测仪上还设有对外的通讯接口。控制电路由电源供电。The realization of the present invention also lies in that the data processing and control circuit installed in the detector includes a microcontroller, a keyboard and a display circuit, a communication interface circuit, an A/D conversion circuit, a low-light detection unit, a light source modulation drive circuit and an LED light emitting The unit, microcontroller and other components are connected with electrical signals, and the tester is also equipped with an external communication interface. The control circuit is powered by the power supply.
本发明设计了以微控制器为控制核心,主要可控参数有调制频率、LED光源开关、光源发光强度,微光检测灵敏度、同步采样频率,以及键盘输入及图形显示等,实时显示检查结果,还可扩展控制一些接口参数,能进行数据和图象处理以及存储、传输或通讯,方便与其他计算机或存储设备连接。The invention is designed with a microcontroller as the control core. The main controllable parameters include modulation frequency, LED light source switch, light source luminous intensity, low-light detection sensitivity, synchronous sampling frequency, keyboard input and graphic display, etc., and the inspection results are displayed in real time. It can also expand and control some interface parameters, and can perform data and image processing as well as storage, transmission or communication, and is convenient to connect with other computers or storage devices.
微控制器为中心的数据处理和控制电路,利用数值计算将大量的牙齿测量数据进行分析和归类,可以剔除操作错误以及对于牙齿具有大的形态学可变性引起的误差,或由于其它原因引起的低于确定值或超过最大值的任何荧光强度的错误信息。实现对光路的发射接收、光电信号的转换、显示电路以及通信的统一调控,可以直接检测和显示牙齿脱矿、龋坏牙本质及牙髓活力的相对应数据,使得牙齿脱矿、龋坏牙本质及牙髓活力检测装置自动化程度更高,还可以进一步方便地实现联网诊断和数据的存储通信。Microcontroller-centered data processing and control circuits, using numerical calculations to analyze and classify a large number of tooth measurement data, can eliminate operational errors and errors caused by large morphological variability of teeth, or caused by other reasons An error message for any fluorescence intensity below the determined value or above the maximum value. Realize the unified control of the transmission and reception of the optical path, the conversion of the photoelectric signal, the display circuit and the communication, and can directly detect and display the corresponding data of tooth demineralization, carious dentin and pulp vitality, making tooth demineralization, carious tooth The essence and pulp vitality detection device has a higher degree of automation, and can further conveniently realize networked diagnosis and data storage and communication.
本发明的实现还在于:接收光路上的滤光器由多个滤光片构成,其中至少包含有三片滤光片,这三个滤光片可通过的荧光光谱范围分别是:440nm-520nm,540nm-550nm及大于600nm的荧光。The realization of the present invention also lies in that the optical filter on the receiving optical path is composed of a plurality of optical filters, at least three optical filters are included, and the fluorescent spectrum ranges that these three optical filters can pass are respectively: 440nm-520nm, Fluorescence at 540nm-550nm and greater than 600nm.
接收光路的滤光器中的滤光片可以方便地切换,以针对牙髓活力状况或龋齿、牙脱矿等病变的检测。The filter in the optical filter of the receiving light path can be switched conveniently, so as to aim at the detection of dental pulp vitality or dental caries, tooth demineralization and other lesions.
本发明通过大量的实验和研究分析发现健康牙齿产生的荧光辐射在470nm-480nm附近存在峰值,也就是在此附近健康牙产生的荧光辐射最强,选用440nm-520nm荧光范围内检测牙髓活力;龋坏牙本质在大于620nm-800nm的荧光范围内存在峰值,比正常牙齿的荧光辐射强,选用大于600nm的荧光范围检测龋齿;牙齿脱矿在440nm-520nm和在540nm-550nm荧光范围内的荧光辐射强度较牙齿健康部分荧光辐射强度有明显的强弱变化,因此本发明优选了健康牙齿与有病牙齿荧光强度对比值大的接收荧光范围。Through a large number of experiments and research analysis, the present invention finds that the fluorescent radiation produced by healthy teeth has a peak value near 470nm-480nm, that is, the fluorescent radiation produced by healthy teeth is the strongest near this, and the pulp vitality is detected within the fluorescent range of 440nm-520nm; The carious dentin has a peak in the fluorescence range greater than 620nm-800nm, which is stronger than the fluorescence radiation of normal teeth. The fluorescence range greater than 600nm is used to detect dental caries; the fluorescence of tooth demineralization is in the fluorescence range of 440nm-520nm and 540nm-550nm Radiation intensity has obvious intensity changes compared with fluorescence radiation intensity of healthy teeth, so the present invention optimizes the receiving fluorescence range where the contrast value of fluorescence intensity between healthy teeth and diseased teeth is large.
本发明的实现还在于:光纤采用石英光纤,其直径为10μm-200μm。The realization of the present invention also lies in that the optical fiber is a quartz optical fiber with a diameter of 10 μm-200 μm.
石英光纤具有光能损耗小,传输效率高的性能,可以很好地完成激励光和荧光辐射的高效传导。Silica optical fiber has the performance of low light energy loss and high transmission efficiency, and can well complete the efficient transmission of excitation light and fluorescent radiation.
本发明的实现还在于:探头的探测端口安装带有窗口的探头帽,探头帽为圆锥台状,保护光纤避免与牙齿或口腔碰撞,并且保证光纤对于荧光辐射的接收处于最佳位置。探头帽为可拆装型,以便可以经常清洁和消毒。The realization of the present invention is also that: the detection port of the probe is equipped with a probe cap with a window, the probe cap is in the shape of a truncated cone, which protects the optical fiber from collision with teeth or oral cavity, and ensures that the optical fiber is in the best position for receiving fluorescent radiation. The probe cap is removable for frequent cleaning and disinfection.
本发明还是一种牙髓活力荧光检测方法,其实现在于:分别用同位或邻位牙齿或者同一牙齿的健康部分荧光强度作为参考;发射光路中调制后的激发光经滤光器后,由发射光纤传输通过探头窗口,照射到被检测牙齿表面,激励牙齿产生荧光辐射,被探头窗口中的接收光纤接收并传输,经滤光片,传送到微光检测单元。检测过程:首先检测和记录健康牙齿或牙齿健康部分的荧光辐射强度作为参考,然后检测被检测牙齿的荧光辐射强度,对两者进行比较,得出判定结果;检测的具体步骤是:The present invention is also a fluorescence detection method for dental pulp vitality, which is achieved by using the same or adjacent teeth or the fluorescence intensity of the healthy part of the same tooth as a reference; The optical fiber transmits through the probe window, irradiates the surface of the tooth to be detected, excites the tooth to generate fluorescent radiation, is received and transmitted by the receiving optical fiber in the probe window, passes through the optical filter, and is transmitted to the low-light detection unit. Detection process: first detect and record the fluorescence radiation intensity of healthy teeth or healthy parts of teeth as a reference, then detect the fluorescence radiation intensity of the detected teeth, compare the two, and obtain the judgment result; the specific steps of detection are:
一.打开电源开关,发射光路中调制后的LED光源发出激发光线;1. Turn on the power switch, and the modulated LED light source in the emission light path emits excitation light;
二.点击功能开关中的校准-测量按钮,校准检测仪进入测量状态;测量状态有两种测量模式,一种是一点测量模式,另一种是多点测定模式;2. Click the calibration-measure button in the function switch, and the calibration detector enters the measurement state; there are two measurement modes in the measurement state, one is a one-point measurement mode, and the other is a multi-point measurement mode;
三.功能开关中的模式选择旋至“单点”,进入一点测量模式,将探头置于健康牙齿或牙齿健康部分的表面,测量荧光辐射强度并存储数据于数据处理和控制电路中,即选择健康牙齿上一个测点进行检测,将测定结果作为测量参考;3. The mode selection in the function switch is turned to "single point" to enter the one-point measurement mode, place the probe on the surface of healthy teeth or healthy teeth, measure the intensity of fluorescent radiation and store the data in the data processing and control circuit, that is, select A measurement point on a healthy tooth is tested, and the measurement result is used as a measurement reference;
四.手持探头,将探头对准被检测牙齿的表面,测量一个测点,测得被检测牙齿的表面荧光辐射强度,并存储数据于数据处理和控制电路中,同时与第三步所录入数据处理和控制电路中的健康牙或牙齿健康部分的参考数据进行比较和处理;4. Hold the probe, aim the probe at the surface of the tooth to be tested, measure a measuring point, measure the surface fluorescence radiation intensity of the tooth to be tested, and store the data in the data processing and control circuit, and at the same time it will be compared with the data entered in the third step Reference data of healthy teeth or teeth healthy parts in the processing and control circuit for comparison and processing;
五.在同一坐标系下健康牙和被检测牙的荧光辐射曲线以及经处理过的比较信息在检测仪的显示屏上同时显示,经数据处理和控制电路检测的数据和图象,由通讯接口电路进行传输和存储。5. Under the same coordinate system, the fluorescence radiation curves of the healthy tooth and the detected tooth and the processed comparison information are displayed on the display screen of the detector at the same time, and the data and images detected by the data processing and control circuit are sent by the communication interface. circuits for transmission and storage.
六.液晶屏幕7显示的比较信息按检测类型分类,不仅可以检测牙髓活力,也可以检测牙齿的其他病症,根据不同的分类可以较直观的判断牙齿的不同病变情况。6. The comparative information displayed on the
本发明采用光学方法进行检测,无痛苦、无刺激,通过微控制器统一控制取样、检测、对比、显示,有效地解决了各种测试干扰和误差纠错,使得整个装置形成一个整体系统,可以方便地操作和检测,也可进一步扩展连接及对所测信息进行更多的对比以及更准确的判定。The present invention uses an optical method for detection, without pain and stimulation, and uniformly controls sampling, detection, comparison, and display through a microcontroller, effectively solving various test interference and error correction, so that the entire device forms an overall system, which can It is convenient to operate and detect, and can further expand the connection and perform more comparisons and more accurate judgments on the measured information.
本发明作为一种牙髓活力荧光检测方法,其实现还在于:多点测定模式,多点测定模式涉及第三步和第四步,具体是:As a fluorescence detection method for dental pulp vitality, the present invention is further implemented in the multi-point measurement mode, which involves the third step and the fourth step, specifically:
三.功能开关中的模式选择旋至“多点”,进入多点测量模式,将探头置于健康牙齿或牙齿健康部分的表面,测量荧光辐射强度并存储数据于数据处理和控制电路中,测量为多点测量模式,即选择健康牙齿或牙齿健康部分上的多个测点进行检测,将测定结果的均值作为测量参考,3. The mode selection in the function switch is turned to "multi-point" to enter the multi-point measurement mode, place the probe on the surface of healthy teeth or healthy teeth, measure the intensity of fluorescent radiation and store the data in the data processing and control circuit, measure It is a multi-point measurement mode, that is, select multiple measurement points on a healthy tooth or a healthy part of the tooth for detection, and use the average value of the measurement results as a measurement reference.
四.手持探头,将探头对准被检测牙齿的表面,测量多个测点,测得被检测牙齿的表面荧光辐射强度,并存储数据于数据处理和控制电路中,同时与第三步所录入数据处理和控制电路中健康牙的参考数据进行比较和处理。4. Hold the probe, aim the probe at the surface of the tooth to be tested, measure multiple measuring points, measure the surface fluorescence radiation intensity of the tooth to be tested, and store the data in the data processing and control circuit, and at the same time record with the third step The reference data of healthy teeth in the data processing and control circuit are compared and processed.
进行第四步时,可以与第三步检测的点数相同,也可不同。When performing the fourth step, the number of points detected in the third step may be the same or different.
由于本发明在总体上将光机电以及计算机技术结合,探索和精选出适当的激励光波长范围、接收荧光波长范围,优选出发射与接收光纤的配比,设计了恰当的光路,可以在自然光环境下应用而不受环境中各种杂光的干扰;选定了健康牙齿与有病牙齿荧光辐射强弱对比度大的检测光谱,检测范围较大,检测准确。针对性的设计了微控制器为中心的数据处理和控制电路,实现了对光路的发射、接收、光电信号的转换、比较分析、显示电路以及通信的统一调控。本发明可选择单点检测和多点检测,具有检测的灵活性。还针对牙齿排列不整齐以及年龄、修补因素等复杂情况进行统计和分类处理,因此在检测过程可以剔除操作错误,也可以剔除由于牙齿具有大的形态学可变性引起的变化引起的误差,或由于其它原因引起的低于确定值或超过最大值的任何错误信息。经过大量的实验和数据统计,获得牙齿脱矿、龋坏牙本质等相对应的荧光辐射强度的比例,以及牙髓活力不同程度的荧光辐射数据。检测装置自动化程度高,还可以进一步方便地实现联网诊断和数据的存储通信。Because the present invention combines opto-mechanical and computer technologies in general, explores and selects the appropriate excitation light wavelength range and receiving fluorescence wavelength range, optimizes the ratio of emitting and receiving optical fibers, and designs an appropriate optical path, which can be used in natural light. It is applied in the environment without interference from various stray lights in the environment; the detection spectrum with a large contrast between the intensity of fluorescent radiation between healthy teeth and diseased teeth is selected, and the detection range is large and the detection is accurate. The microcontroller-centered data processing and control circuit is designed in a targeted manner, which realizes the unified control of the transmission, reception, photoelectric signal conversion, comparative analysis, display circuit and communication of the optical path. The present invention can select single-point detection and multi-point detection, and has the flexibility of detection. Statistical and classification processing is also carried out for complex situations such as irregular tooth arrangement, age, and repair factors, so that operational errors can be eliminated during the detection process, and errors caused by changes caused by large morphological variability of teeth, or errors caused by Any error message below the specified value or exceeding the maximum value due to other reasons. After a large number of experiments and data statistics, the proportion of fluorescence radiation intensity corresponding to tooth demineralization and carious dentin, as well as the fluorescence radiation data of different degrees of pulp vitality were obtained. The detection device has a high degree of automation, and can further conveniently realize networked diagnosis and data storage and communication.
本发明解决了快速,直观,准确,无痛无刺激,进行牙表面的荧光检测的技术问题,还解决了快速检测牙齿脱矿、龋坏牙本质及牙髓活力的专业难题,综合性强,统一控制,结构简单,不受口腔环境影响和干扰。The invention solves the technical problem of fast, intuitive, accurate, painless and non-irritating fluorescence detection on the tooth surface, and also solves the professional problems of rapid detection of tooth demineralization, carious dentin and pulp vitality, and is comprehensive. Unified control, simple structure, free from oral environment influence and interference.
实现了同步检测与显示,可以用于口腔医院、牙科诊所等需要对牙病进行检测的场所。是每个牙科医疗诊所应该必备的设备。It realizes synchronous detection and display, and can be used in dental hospitals, dental clinics and other places that need to detect dental diseases. It is a must-have device for every dental clinic.
附图说明:Description of drawings:
图1是本发明的总体构成示意图;Fig. 1 is the overall composition schematic diagram of the present invention;
图2是本发明的光路传输示意图;Fig. 2 is a schematic diagram of optical path transmission of the present invention;
图3是本发明的数据处理和控制电路构成方框图;Fig. 3 is a block diagram of data processing and control circuits of the present invention;
图4是本发明光纤束的发射光纤和接收光纤分配比例示意图;Fig. 4 is a schematic diagram of distribution ratios of the transmitting optical fiber and the receiving optical fiber of the optical fiber bundle of the present invention;
图5是本发明探头的结构示意图。Fig. 5 is a schematic diagram of the structure of the probe of the present invention.
具体实施方式:Detailed ways:
实施例1:参见图1,本发明作为牙髓活力荧光检测装置,具有光学处理单元,主要是有产生激励光的发光部分、接收牙齿表面荧光辐射的光接收部分、将接收到的荧光辐射与健康牙齿荧光辐射进行比较的比较装置以及用于传导光的光纤束,本发明产生激励光的光源10是调制光源;检测装置还包括有检测仪1,从检测仪1中接出的光纤束2,光纤束2的一头分为两束,一束为激发光纤8,其端面对准发射光路的滤光器11,另一束为接收光纤9,其端面对准荧光接收光路的滤光器13,参见图2。发射光路的发光器件10为可见光中包含有紫光的光源,如紫光发光二极管、卤钨灯等,它可以避免短波光线对人体造成得伤害。聚光镜12可以将较多的激励光线汇聚到发射光纤8中。Embodiment 1: Referring to Fig. 1, the present invention, as a fluorescence detection device for dental pulp, has an optical processing unit, mainly including a light-emitting part that generates excitation light, a light-receiving part that receives fluorescent radiation on the tooth surface, and combines the received fluorescent radiation with A comparison device for comparing the fluorescent radiation of healthy teeth and an optical fiber bundle for conducting light, the
本例中发光器件10选择紫光LED,发射光路上设有的滤光器11可通过激励光的波长是410nm-430nm,本例中选用420nm,误差为±5nm的滤光片来实现。接收光路上的滤光器本例中选用480nm,误差为±5nm的滤光器,实现对牙髓活力的检测。光纤束2的另一端与探头3连接,光纤束2的直径为2mm,在光纤束2中发射光纤8与接收光纤9的数量比例为2/5比3/5,见图4。探头3的探测端口安装带有窗口的探头帽15,方便拆卸和安装。检测仪1的面板上有液晶显示屏7、功能开关6和小型键盘5,检测仪1内安装数据处理和控制电路、光学处理单元。In this example, the light-emitting
荧光经接收光路的滤光器13滤除杂散光和非检测荧光后,只允许适合检测、判别牙齿病变的荧光谱线通过,见图2,过滤后的荧光进入微光检测单元中的光电转换探测器14,光电探测器14可以是光电二极管、光电倍增管或其他光电转换器件转变为电信号,再经过放大、解调、存入数据处理与控制电路。同一坐标系下健康牙齿和被检测牙齿4的荧光强度曲线以及经处理过的比较信息在检测仪1的显示屏7上同时显示,经数据处理和控制电路检测的数据和图象,由通讯接口电路进行传输和存储。微机信息处理系统将接收到的健康牙齿和有病牙齿的荧光信息显示在液晶屏幕上,供医生做出判断,也可以将此次信息进行存储,或将有病牙的荧光数据同数据库里存储的数据进行比较。Fluorescence passes through the
光纤采用石英光纤,传输性能好,光纤的直径为50μm。The optical fiber adopts quartz optical fiber, which has good transmission performance, and the diameter of the optical fiber is 50 μm.
实施例2:参见图4,总体构成同实施例1,检测仪1内引出的光纤束2内的直径为2.5mm,光纤的直径为200μm。探头3的探测端口安装带有窗口的探头帽15为圆锥台状。见图5,通过罗纹连接,以便探头帽15可以经常清洁和消毒。Embodiment 2: Referring to FIG. 4 , the overall structure is the same as that of
实施例3:参见图4,总体构成同实施例1,检测仪1内引出的光纤束2的直径为2.2mm,光纤的直径为100μm。参见图5,圆锥台状的探头帽15与手持部分通过锥度旋转固紧,方便拆装,以便探头帽15可以经常清洗和消毒。另外探头3头部的探头帽15还保证光纤的端部离开牙齿表面0.5mm-1mm,使激励光线激发的荧光能够尽可能多的进入接收光纤9,也保护光纤头部不受损坏。Embodiment 3: Referring to FIG. 4 , the overall structure is the same as that of
实施例4:参见图4,总体构成同实施例2,检测仪1内引出的光纤束2的直径为1.6mm,光纤的直径为10μm。Embodiment 4: Referring to FIG. 4 , the overall structure is the same as that of
实施例5:参见图3,总体构成同实施例1,在检测仪1中安装的控制电路是包括有微控制器、键盘及显示电路、通讯接口电路、A/D转换电路、微光检测单元、光源调制驱动电路和LED发光装置,微控制器与其他组成电路均有电信号连接。光源调制驱动电路同步接收微控制器的控制信号和微控制器的调制信号,该调制信号即矩形脉冲,光源调制驱动电路的输出端接LED发光器件的输入端,LED发光器件直对光学滤器11;A/D转换电路接收微光检测单元输出的放大的模拟电信号,同时接收微控制器的控制信号,A/D转换电路输出接微控制器通用IO口。Embodiment 5: referring to Fig. 3, overall composition is the same as
控制电路以微控制器为控制核心,主要可控参数有调制频率、LED光源开关、光源发光强度,微光检测灵敏度、同步采样频率,以及键盘输入及图形显示等,还可扩展控制一些接口参数,方便与其他计算机或存储设备连接。The control circuit uses a microcontroller as the control core. The main controllable parameters include modulation frequency, LED light source switch, light source luminous intensity, low-light detection sensitivity, synchronous sampling frequency, keyboard input and graphic display, etc., and some interface parameters can also be extended to control , for easy connection with other computers or storage devices.
工作时,微控制器输出1~1KHz频率的矩形脉冲到光源调制驱动电路,使得LED发光管10按照一定频率闪烁。调制光源的主要目的是消除环境光干扰,利于检测电路检测。由于微控制器输出的矩形脉冲为5V的脉冲信号,且驱动能力较弱,需要增加一级驱动电路,来控制发光庄置。调制频率的设定主要受限于发光器件的频率特性,并且根据使用调制光源的目的,使用的调制频率不需要太高,可简化电路,因此选定1~1KHz。微控制器输出一控制信号控制LED是否发光,可以在非检测状态或其他特殊条件下,关闭发光LED,以延长其寿命。When working, the microcontroller outputs a rectangular pulse with a frequency of 1-1KHz to the light source modulation drive circuit, so that the LED light-emitting
实施例6:总体构成同实施例5,微光检测单元电路主要由光电转换探测器14、放大解调电路组成,光电转换探测器14采用光电倍增管,微光检测单元中的光电转换探测器14检测到荧光后,由微控制器设定的灵敏度通过放大解调电路进行信号放大,由于荧光信号强弱变化范围较大,信号放大倍数可根据具体情况调整。输出模拟信号由微控制器控制A/D转换器进行同步转换。为了消除干扰,可在一个发光周期内进行多次采样,实现多点检测,转换以后的数字信号经软件做去噪处理后,由液晶显示器以图线和数值的方式进行显示。Embodiment 6: The overall composition is the same as in
所有参数都可以通过小键盘5进行设置,并在显示屏7上同步显示更新。All parameters can be set through the
实施例7:总体构成同实施例6,接收光路上的滤光器13由多个滤光片构成,其中至少包含有三片滤光片,这三个滤光片可通过的荧光光谱范围分别是:440nm-520nm,540nm-550nm及大于600nm的荧光。可以将多个滤光片安装于一圆盘的同直径的圆环上,旋转圆盘各滤光片可方便地切换。Embodiment 7: The overall composition is the same as that of
实施例8:牙髓活力和牙菌斑的检测:Example 8: Detection of pulp vitality and dental plaque:
牙髓活力检测:Pulp vitality test:
接收光路上的滤光器切换滤光片使通过的荧光范围分别是:460nm-520nm的荧光,用于检测牙髓活力,因为健康牙齿在470nm-480nm存在荧光辐射的峰值,而失去或减弱活力的牙齿在此范围荧光辐射减弱明显,活力检测用同位或邻位牙齿进行,检测更准确。检测牙髓活力时接收光路用480nm--490nm滤光片,首先检测同位或邻位健康、干净牙齿的荧光辐射强度作为参考,然后检测怀疑有病牙齿的荧光辐射强度,比较两次的检测结果,如果检测牙齿的荧光强度小于健康牙齿荧光强度的25%,可以判断该牙为死髓牙。如果检测牙齿荧光强度小于健康牙齿荧光强度的10%--20%,可以考虑为活力正在减弱。The filter on the receiving light path switches the filter so that the fluorescence ranges that pass are: 460nm-520nm fluorescence, which is used to detect the vitality of the pulp, because healthy teeth have a peak of fluorescence radiation at 470nm-480nm, and lose or weaken vitality The fluorescent radiation of the teeth in this range is significantly weakened, and the vitality detection is performed with the same or adjacent teeth, and the detection is more accurate. 480nm--490nm optical filter is used in the receiving light path when detecting pulp vitality. First, detect the fluorescence radiation intensity of the same or adjacent healthy and clean teeth as a reference, and then detect the fluorescence radiation intensity of suspected diseased teeth, and compare the two detection results. , if the fluorescence intensity of the detected tooth is less than 25% of the fluorescence intensity of healthy teeth, it can be judged that the tooth is a tooth with dead pulp. If the fluorescence intensity of detected teeth is less than 10%-20% of the fluorescence intensity of healthy teeth, it can be considered that the vitality is weakening.
牙菌斑检测:Plaque detection:
接收光路用480nm--490nm滤光片,检测同一牙齿不同部位的荧光强度,如果一处比另一处低超过15%时,低处应考虑有牙菌斑的存在,牙菌斑处在清除荧光辐射强度后会明显提高。Use a 480nm--490nm filter in the receiving light path to detect the fluorescence intensity of different parts of the same tooth. If one part is more than 15% lower than the other part, the presence of dental plaque should be considered in the low part, and the dental plaque is being removed. Fluorescent radiation intensity will be significantly increased after.
实施例9:总体构成同实施例6,检测牙齿脱矿时,切换滤光片使接收光路先选用480nm--490nm滤光片,检测同一牙齿相邻部位的荧光强度,如果一处比周边低20%左右时,应考虑低处有牙齿脱矿存在,再选用540nm--550nm滤光片检测,如果此处比周边低的差值减小至10%以下或者比周边高时,即可以进行确认。接收光路上的滤光器中荧光范围540nm-550nm的滤光片主要用于牙脱矿的确认检测。Embodiment 9: The overall structure is the same as in
实施例10:总体构成同实施例6,接收光路上的滤光器切换滤光片采用通过的荧光光谱范围大于600nm截止滤光片,检测同一牙齿相邻部位的荧光强度,如果一处比周边高20%左右时,应考虑高处有龋齿存在。Embodiment 10: The overall composition is the same as that of
实施例11:采用塑料光纤,可以降低造价和成本。Embodiment 11: By using plastic optical fiber, the cost and cost can be reduced.
实施例12:总体构成同实施例10,接收光路上的滤光器切换滤光片采用通过的荧光光谱范围大于650nm截止滤光片,用于测龋齿。Embodiment 12: The overall structure is the same as that of
实施例13:检测装置采用同实施例1~9的装置,牙髓活力荧光检测方法是:调制后的激发光经滤光器11后,由发射光纤8传输通过探头3窗口,照射到被检测牙齿4表面,激励牙齿产生荧光辐射,被探头3窗口中的接收光纤9接收并传输,经滤光片13,传送到微光检测单元。检测过程:首先检测和记录健康牙齿或牙齿健康部分的荧光辐射强度作为参考,然后检测被检测牙齿4的荧光辐射强度,对两者进行比较,得出判定结果,检测的具体步骤是:Embodiment 13: The detection device adopts the same device as in
一.打开电源开关,发射光路中调制后的LED光源10发出激发光线;1. Turn on the power switch, and the modulated
二.点击功能开关6中的校准-测量按钮,校准检测仪1进入测量状态;测量状态有两种测量模式,一种是一点测量模式,另一种是多点测定模式;2. Click the calibration-measurement button in the
三.功能开关6中的模式选择旋至“单点”,进入一点测量模式,将探头3置于健康牙齿或牙齿健康部分的表面,测量荧光辐射强度并存储数据于数据处理和控制电路中,即选择健康牙齿或牙齿健康部分上的一个测点进行检测,将测定结果作为测量参考,3. The mode selection in the
四.手持探头3,将探头对准被检测牙齿4的表面,测量一个测点,测得被检测牙齿4的表面荧光辐射强度,并存储数据于数据处理和控制电路中,同时与第三步所录入数据处理和控制电路中的健康牙齿的参考数据进行比较和处理;4. Hand-hold the
五.在同一坐标系下健康牙齿或牙齿健康部分和被检测牙齿4的荧光辐射曲线以及经处理过的比较信息在检测仪1的显示屏7上同时显示,经数据处理和控制电路检测的数据和图象,由通讯接口电路进行传输和存储。5. Under the same coordinate system, the fluorescence radiation curves of healthy teeth or teeth healthy parts and detected
六.液晶屏幕7显示的比较信息按检测类型分类,根据本发明可以检测牙髓活力,也可以检测牙齿的其他病症,即牙髓活力,牙齿脱矿,龋齿和牙菌斑等,可以较直观的判断牙齿的不同病变情况。Six. The comparative information displayed on the
检测牙髓活力时接收光路用480nm--490nm滤光片,首先检测同位或邻位健康、干净牙齿的荧光强度作为参考,然后检测怀疑有病牙齿的荧光强度,比较两次的检测结果,如果检测牙齿的荧光强度小于健康牙齿荧光强度的25%,可以判断该牙为死髓牙。如果检测牙齿荧光强度小于健康牙齿荧光强度的10%--20%,可以考虑为活力正在减弱。When detecting pulp vitality, use a 480nm--490nm filter for the receiving light path, first detect the fluorescence intensity of the same or adjacent healthy and clean teeth as a reference, and then detect the fluorescence intensity of the suspected diseased tooth, compare the two detection results, if If the fluorescence intensity of the detected tooth is less than 25% of the fluorescence intensity of the healthy tooth, it can be judged that the tooth is a tooth with dead pulp. If the fluorescence intensity of detected teeth is less than 10%-20% of the fluorescence intensity of healthy teeth, it can be considered that the vitality is weakening.
检测牙菌斑时接收光路用480nm--490nm滤光片,检测同一牙齿不同部位的荧光强度,如果一处比另一处低超过15%时,低处应考虑有牙菌斑的存在。When detecting dental plaque, the receiving light path uses a 480nm--490nm filter to detect the fluorescence intensity of different parts of the same tooth. If one part is lower than the other by more than 15%, the presence of dental plaque should be considered in the lower part.
检测牙齿脱矿时接收光路先用480nm--490nm滤光片,检测同一牙齿相邻部位的荧光强度,如果一处比周边低20%左右时,应考虑低处有牙齿脱矿存在,再选用540nm--550nm滤光片检测,如果此处比周边低的差值减小至10%以下或者比周边高时,即可以进行确认。When detecting tooth demineralization, the receiving light path first uses a 480nm--490nm filter to detect the fluorescence intensity of the adjacent parts of the same tooth. If one place is about 20% lower than the surrounding area, it should be considered that there is tooth demineralization in the lower place, and then choose 540nm--550nm filter detection, if the difference lower than the surrounding area is reduced to less than 10% or higher than the surrounding area, it can be confirmed.
检测牙齿龋坏时接收光路选用通过大于600nm荧光的滤光片,检测同一牙齿相邻部位的荧光强度,如果一处荧光强度比周边高超过20%时,应考虑高处有牙齿龋坏的存在。When detecting dental caries, the receiving light path is selected to pass through a fluorescence filter greater than 600nm, and the fluorescence intensity of the adjacent parts of the same tooth is detected. If the fluorescence intensity of one place is more than 20% higher than that of the surrounding area, it should be considered that there is tooth decay in the high place .
实施例14:装置和方法均同实施例10,不同之处是多点测定模式,涉及第三步和第四步,具体是:Embodiment 14: The device and method are the same as in
三.功能开关6中的模式选择旋至“多点”,进入多点测量模式,将探头3置于健康牙齿或牙齿的健康部分的表面,测量荧光辐射强度并存储数据于数据处理和控制电路中,测量为多点测量模式,即选择健康牙齿或牙齿健康部分上的多个测点进行检测,将测定结果的均值作为测量参考,3. The mode selection in the
四.手持探头3,将探头对准被检测牙齿4的表面,测量多个测点,测得被检测牙齿4的表面荧光辐射强度,并存储数据于数据处理和控制电路中,同时与第三步所录入数据处理和控制电路中的健康牙齿或牙齿的健康部分的参考数据进行比较和处理;4. Hold the
进行第四步时,与第三步检测的点数相同。When performing the fourth step, the number of points detected in the third step is the same.
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