CN101167466B - Insecticidal composition containing avermectin with synergistic effect - Google Patents
Insecticidal composition containing avermectin with synergistic effect Download PDFInfo
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- CN101167466B CN101167466B CN2007101952670A CN200710195267A CN101167466B CN 101167466 B CN101167466 B CN 101167466B CN 2007101952670 A CN2007101952670 A CN 2007101952670A CN 200710195267 A CN200710195267 A CN 200710195267A CN 101167466 B CN101167466 B CN 101167466B
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- avermectin
- nitenpyram
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- effect
- insecticides
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Abstract
The invention relates to an insecticide compound of avermectin and nitenpyram, which is characterized in that the effect components of the invention are avermectin and nitenpyram, and the mass ratio of avermectin and nitenpyram is between 0.1:50 and 5:1. The invention has the advantages that obvious synergy effect and persistent effect can be achieved after remixing, and plural functions of broadspectrum, high efficiency, low toxicity, low pollution and low residual against aphides, whiteflies, spiny white flies, tobacco whiteflies and the like which are common on fruit trees and cotton can be achieved. Besides, the consumption and application times of pesticide are substantially decreased, costs are reduced and the drug resistance of pests is retarded.
Description
Technical field
The invention belongs to technical field of compounded pesticide, the richness that is specifically related to a kind of Avermectin and Nitenpyram is joined agricultural chemicals.
Background technology
Avermectin: be a kind of macrolide disaccharide compounds.Be the natural products that from edaphon, separates, insect and mite class had tag and stomach poison function and faint fumigation action is arranged, no systemic action.But it has very strong osmosis to blade, can kill subepidermal insect, and the longevity of residure is long.It does not kill ovum.What its mechanism of action was different with general insecticide is that it disturbs the neurophysiology activity, stimulate and discharge r one aminobutyric acid, and r one aminobutyric acid has inhibitory action to arthropodan nerve conduction, the mite class becomes, if mite and insect and larva with paralysis symptom promptly appears after medicament contacts, inertia is not got food, and is dead after 2-4 days.Because of not causing that insect dewaters rapidly, so its lethal effect is slower.But though predatism and parasite are had direct killing effect, because of plant surface is residual few, therefore little to the damage of beneficial insect.English with using name: abamectin.
Structural formula:
Molecular formula: C
48H
72O
14(B
1a) C
47H
70O
14(B
1b)
Molecular weight: 859.1
Nitenpyram: this crystalline substance belongs to the nicotimine insecticides, is widely used in paddy rice, fruit tree, vegetables and tealeaves, prevents and treats various pests.Especially vegetable aphid there is good preventive effect.English common name: nitenpyram, chemical name: (E)-N-(6-chloro-base 3-is than pyridine methyl)-N-ethyl-N '-methyl-2-nitro ethenylidene diamines.
Structural formula:
Often there is defective in various degree in the insecticide variety that contains a kind of active component on agricultural insect pests control: use insect to be easy to generate pesticide resistance continuously, access times cause the pollution grows worse of environment etc. more.And become the blending ingredients insecticide can effectively overcome above shortcoming by the insecticide mixture of two or more active component.Simultaneously, utilize two kinds of synergistic effects that active component is mixed and is produced, can improve preventive effect, reduce the consumption of active ingredient, save cost, delay the generation of pest resistance to insecticide, and reduce that some contains the existing report of insecticides of Avermectin dual-active component to the pollution of environment, the richness that openly contains Avermectin as: CN1957708A is joined the worm composition of stopping.But, do not see the report of the insecticides that Avermectin and Nitenpyram are formed so far.
Summary of the invention
Advantage of the present invention and good effect: in agricultural insecticide, selectively the agricultural chemicals of two or more different molecular structures types, different insecticidal mechanism and different insecticidal spectrums is carried out compositely, be the control resistant insect, enlarge insecticidal spectrum, improve drug effect, the effective way of delaying drug resistance development.The present invention utilizes macrolide disaccharide insecticides and pyrethroid insecticides two insecticides agricultural chemicals to carry out binary built, has reached above-mentioned purpose, has improved the drug effect that prevents resistant insect, has enlarged insecticidal spectrum, and can delay the development of pest resistance to insecticide.
A kind of insecticides of the present invention, active ingredient are Avermectin and Nitenpyram, and the weight proportion of Avermectin and Nitenpyram is between 0.1: 50 to 5: 1.
Described Avermectin can be Avermectin or ivermectin.
The formulation of the insecticides of described Avermectin and Nitenpyram is a wetting powder, water dispersible granules, suspending agent, aqueous emulsion, effervescent tablet.
Wetting powder contains 10～85% active components usually, except solid inert carrier, contains 3～10% dispersants usually, can also contain 0～10% stabilizing agent or other additive for example bleeding agent or sticker.
Water dispersible granules is made 10～100 international standard sieve meshes usually, and (1.676～0.152mm) particles can be by extruding, dipping or the preparation of mist projection granulating method.Usually granule contains 0.5～75% active component, and is external except solid, inert, contains 0～10% additive such as stabilizing agent, surfactant, slow release regulator and adhesive usually.
Suspending agent contains 5～75% active components usually, 0.5～15% dispersant, 0.1～10% thixotropic agent, 0～10% other additive such as defoamer, corrosion inhibitor, stabilizing agent, bleeding agent and thickener, and water or organic liquid, wherein active component is undissolved basically.Some organic solid or mineral salt can be dissolved in the preparation, to help preventing deposition or as antifreezing agent.Suspending agent need grind usually to obtain stable non-deposition flowable product.
The composition (by the mass component proportional meter) that the invention provides the effervescent tablet of a kind of Avermectin and Nitenpyram is composed as follows:
5 parts～650 parts of bulk drugs
5 parts～50 parts of wetting agents
20 parts～100 parts of dispersants
0 part～50 parts of lubricants
100 parts～300 parts of acid effervescent agent
100 parts～300 parts of alkalescence effervescent agent
0 part～500 parts of thinners
0 part～30 parts in adhesive
Effervescent tablet is shaped as circular or erose tablet, and every weight is counted: 0.5～5g; Get 1～5 of effervescent tablet and add water to 1000～3000 times of sprayings.
Described wetting agent has: sodium alkyl sulfate, alkylbenzenesulfonate, Fluhyzon formaldehyde condensation products, alkyl phenol polyether, fatty alcohol-polyoxyethylene ether, Tween-60, Tween-80 one of them or two or more combination.
Described dispersant has: polycarboxylate, lignosulfonates, Fluhyzon formaldehyde condensation products, sulfite cellulose solid dry substance, oxirane propylene oxide block copolymer, can use separately, but also two or more mixes use.
Described acid effervescent agent has: citric acid, tartaric acid one of them or two kinds of combinations.
Described alkaline effervescent agent has: sodium carbonate, sodium bicarbonate one of them or two kinds of combinations.
Described thinner has: starch, ammonium sulfate, potassium chloride, kaolin, bentonite, white carbon, can use separately, but also two or more mixes use.Described lubricant has: Macrogol 6000, starch one of them or two kinds of combinations.
Under lubricant have: wherein one or both or the two or more combination of Macrogol 6000, talcum powder, dolomol, alkyl sulfate.
The present invention compared with prior art, it is simple to have production technology, cost is low, easy to use, operator ' s health is not had the injury and the characteristics of environmentally safe, and the while is adjuvant used, and carrier is nonhazardous, pollution-free, reduced pollution, be applicable to the control cotton aphid environment and operating personnel.
The invention has the advantages that and utilize two kinds of synergistic effects that active component is mixed and is produced, improved preventive effect, reduce the consumption of active ingredient, delay the generation of pest resistance to insecticide, and reduce environment, pollution.
Embodiment
Embodiment 1: aphid
By Avermectin weight proportion (unless he does not mentionlet alone bright, average percentage by weight) 5%, Nitenpyram 30%, dispersant sodium lignin sulfonate 15%, disintegrant aluminium chloride 4%, stabilizing agent tributyl phosphate 1.5%, wetting agent draws back powder 5%, and carrier bentonite 39.5% is made water dispersible granules.This prescription is by 2000～2500 times of dilution sprayings, and 72 hours field control effects are 98.10% behind the medicine.5% Avermectin water dispersible granules and 30% Nitenpyram, water dispersible granules is according to using with quadrat method, and 72 hours preventive effect branches are not 55.05% and 55.91% in addition behind the medicine.
Embodiment 2: aphid
By Avermectin weight proportion (unless he does not mentionlet alone bright, average percentage by weight) 5%, Nitenpyram 30%, dispersant sodium lignin sulfonate 15%, disintegrant 4%, stabilizing agent BHT1.5%, thickener gum Arabic 5%, antifreezing agent urea 0.5%, wetting agent draws back powder 5%, and water is mended to 100%.Make composition suspending agent.This prescription is by 2000～2500 times of dilution sprayings, and 72 hours field control effects are 90.98% behind the medicine.5% Avermectin suspending agent and 30% Nitenpyram, suspending agent is according to using with quadrat method, and 72 hours preventive effects are respectively 41.04% and 43.21% behind the medicine.
Embodiment 3: aphid
By Avermectin weight proportion (unless he does not mentionlet alone bright, average percentage by weight) 1%, Nitenpyram 30%, dispersant sodium lignin sulfonate 15%, stabilizing agent tributyl phosphate 1.5%, wetting agent draw back powder 5%, and carrier bentonite 47.5% is made wetting powder.This prescription is by 2000～2500 times of dilution sprayings, and 72 hours field control effects are 92.07% behind the medicine.1% Avermectin wetting powder and 30% Nitenpyram, wetting powder is according to using with quadrat method, and 72 hours preventive effects are respectively 48.09% and 43.07% behind the medicine.
Can draw by embodiment 1,2,3: be to use more than 2 times of single agent Avermectin or Nitenpyram with sample ingredient Avermectin and the composite back control efficiency of Nitenpyram to aphid.
Embodiment 4 Avermectin are mixed the indoor determination of activity experiment of use with Nitenpyram
For the examination object; Aphid, the sensitive strain of indoor feeding.
Reagent agent: the former medicine content 95% of Avermectin, the former medicine content 95% of Nitenpyram.
Supply strip spare: temperature: 24～26 ℃, humidity: RH60%, illumination: L: D=14: 10
Test method: accurately take by weighing reagent agent respectively with electronic analytical balance, relate to the serial soup that dosage is diluted to tool finite concentration gradient respectively by test in water.
Test adopts infusion process to handle, and the band root vegetables bean seedlings that will have two true leaves are put into test tube and cultivated with clear water, and every test tube one young plant connects 40～60 of healthy and strong adults on every young plant.The Kidney bean seedling that is connected to adult was flooded 5 seconds in the good soup of dilution, put back to former test tube after the taking-up.Handle blank earlier, relate to dosage order from low to high by test then and repeat aforesaid operations, every processing repeats for 3 times.
Examination material after handling is placed in the observation ward dead, the borer population of living of 48h " Invest, Then Investigate ".
With abbott formula calculation correction lethality, the appliance computer program is obtained each for trying virulence regression equation formula, the LC that single agent and variant proportioning are used with
50Value and 95% confidence limit are calculated co-toxicity coefficient with the abundant method of Sun Yun, estimate and use effect with.
Result of the test sees Table 1:
Table 1 Avermectin Nitenpyram is to the indoor joint toxicity measuring result of cotton aphid
Claims (2)
1. the insecticides of Avermectin and Nitenpyram is characterized in that active ingredient is Avermectin and Nitenpyram, and the weight proportion of Avermectin and Nitenpyram is 1: 10 to 5: 1.
2. insecticides according to claim 1 is characterized in that, the formulation of this insecticides is wetting powder, water dispersible granules, suspending agent, aqueous emulsion, effervescent tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101952670A CN101167466B (en) | 2007-12-05 | 2007-12-05 | Insecticidal composition containing avermectin with synergistic effect |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2007101952670A CN101167466B (en) | 2007-12-05 | 2007-12-05 | Insecticidal composition containing avermectin with synergistic effect |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101167466A CN101167466A (en) | 2008-04-30 |
| CN101167466B true CN101167466B (en) | 2010-06-02 |
Family
ID=39388330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2007101952670A Expired - Fee Related CN101167466B (en) | 2007-12-05 | 2007-12-05 | Insecticidal composition containing avermectin with synergistic effect |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101167466B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103181392B (en) * | 2013-01-17 | 2015-05-13 | 华中农业大学 | Mixture preparation of nitenpyram and abamectin and preparation method |
| CN106165690A (en) * | 2016-07-21 | 2016-11-30 | 佛山市盈辉作物科学有限公司 | A kind of composition pesticide containing avilamycin |
| CN107258800A (en) * | 2017-05-26 | 2017-10-20 | 河北威远生物化工有限公司 | A kind of composition pesticide containing avermectin B2a |
-
2007
- 2007-12-05 CN CN2007101952670A patent/CN101167466B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101167466A (en) | 2008-04-30 |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Shaanxi Welch Crop Protection Co., Ltd. Assignor: Zhang Shaowu Contract record no.: 2011610000013 Denomination of invention: Insecticidal composition containing avermectin with synergistic effect Granted publication date: 20100602 License type: Common License Open date: 20080430 Record date: 20110310 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170109 Address after: 715500 Shaanxi Pucheng County agricultural base industrial park Patentee after: Shaanxi Meibang Pesticides Co., Ltd. Address before: 715500 Pucheng province Shaanxi County Chengguan Town Food City Street No. 23 Patentee before: Zhang Shaowu |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100602 Termination date: 20171205 |
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| CF01 | Termination of patent right due to non-payment of annual fee |