CN101095938A - Chinese traditional medicine for treating diabetic ischemic muscular atrophy - Google Patents
Chinese traditional medicine for treating diabetic ischemic muscular atrophy Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal preparation for treating diabetic muscular dystrophies, which is prepared from more than ten kinds of Chinese medicinal herbs including pseudostellaria root, coix seed, astragalus root and white atractylodes rhizome. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to treat a kind of Chinese medicine of diabetic amyotrophy, is that a kind of diabetic amyotrophy for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
That diabetic amyotrophy is more common in is older, diabetic duration short and it is bad to control, and general onset is more anxious, suitably can take a turn for the better rapidly after the control of diabetes.Clinical manifestation is the lower limb weakness, and difficulty in walking accompanies by wasting, claims the diabetic duchenne muscular dystrophy again.Mainly be unsymmetry or one-sided property, based on the amyotrophy of pelvic girdle, huckle, minority can merge the amyotrophy or the far-end of limb amyotrophy of pectoral girdle, upper arm.It is low to suffer from muscle tone, and tendon reflex weakens disappearance, muscle package can occur and quiver, and accompanies by pathologic reflex, and skeleton myalgia, minority can have burst a portion's hypalgesia or a disappearance, but most sensory disturbance is not obvious.Electromyogram inspection prompting muscle be primary affection with neuropathy, protein raises obviously in the cerebrospinal fluid, intramuscular biopsy prompting muscle fiber atrophy.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as QI and blood deficiency, deficiency of kidney-essence clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetic amyotrophy.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Radixs Astragali of 1.5～6 parts of Radix Pseudostellariaes of Semen Coicis
1.0～4 parts of 1.0～4 parts of Pericarpium Citri Reticulataes of 1.0～4 parts of Radix Angelicae Sinensis of Rhizoma Atractylodis Macrocephalae (parched)
0.1～2 part of 1.0～4 parts of Radix Polygalae of 1.0～4 parts of Poria of Radix Rehmanniae Preparata
0.1～2 part of 0.1～2 part of Fructus Tsaoko of 0.1～2 portion of Rhizoma Zingiberis of Radix Glycyrrhizae.
The weight proportion of each raw material of optimization formula of the present invention is:
2.5～3.5 parts of 2.5～3.5 parts of Radixs Astragali of 2.5～3.5 parts of Radix Pseudostellariaes of Semen Coicis
1.5～2.5 parts of 1.5～2.5 parts of Pericarpium Citri Reticulataes of 1.5～2.5 parts of Radix Angelicae Sinensis of Rhizoma Atractylodis Macrocephalae (parched)
0.5～1.5 part of 1.5～2.5 parts of Radix Polygalae of 1.5～2.5 parts of Poria of Radix Rehmanniae Preparata
0.5～1.5 part of 0.5～1.5 part of Fructus Tsaoko of 0.5～1.5 portion of Rhizoma Zingiberis of Radix Glycyrrhizae.
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of Radixs Astragali of 3 parts of Radix Pseudostellariaes of Semen Coicis
2 parts of 2 parts of Pericarpium Citri Reticulataes of 2 parts of Radix Angelicae Sinensis of Rhizoma Atractylodis Macrocephalae (parched)
1 part of 2 parts of Radix Polygalae of 2 parts of Poria of Radix Rehmanniae Preparata
1 part of 1 part of Fructus Tsaoko of 1 portion of Rhizoma Zingiberis of Radix Glycyrrhizae.
Drug action mechanism among the present invention is as follows:
The Semen Coicis property of medicine is sweet, light, is slightly cold.Return spleen, stomach, lung meridian.Has the dampness removing spleen invigorating, arthralgia relieving by relaxing muscles and tendons, the effect of clearing away heat and discharging pus.Can treat edema, beriberi, dribbling urination, damp-warm diseases is had loose bowels, leukorrhagia, rheumatic arthralgia, the contracture of muscle arteries and veins, lung abscess, acute appendicitis, verruca plana etc.(the 3725th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Pseudostellariae property of medicine is slightly cold.Return spleen, lung meridian.Has supplementing QI for promoting the production of body fluid, the effect of spleen reinforcing lung moistening.It is tired to treat insufficiency of the spleen body, inappetence, and impairment of both QI and YIN, dry cough expectorant is few, and spontaneous perspiration is breathed hard, and interior-heat is thirsty, the neurasthenia, palpitation and insomnia, dizzy forgetful, children's's summer fever etc.(the 534th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Atractylodis Macrocephalae (parched) hardship, sweet, temperature.Return spleen, stomach warp.Has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Can treat the weak of deficiency-weakness of spleen-QI, lack of appetite abdominal distention is had loose bowels, constipation, the dysuria of fluid-retention stagnating in the interior, edema, dizziness due to fluid-retention, cold-damp numbness, general pain, spontaneous sweating due to deficiency of QI, frequent fetal movement etc.(the 945th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Polygalae property of medicine suffering, hardship, tepor.GUIXIN, lung, kidney channel.Have mind tranquilizing and the heart calming, eliminate the phlegm and have one's ideas straightened out, the effect of removing toxic substances and promoting subsidence of swelling.Can treat irritability, the palpitation with fear insomnia, forgetful, infantile convulsion, cough with copious phlegm, carbuncle carbuncle on the back, breast swell and pain etc.(the 1436th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Glycyrrhizae property of medicine is sweet, and is flat.Return spleen, stomach, the heart, lung meridian.Have and middle emergency lung moistening, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Can treat weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough; Give birth to controlling laryngopharynx swelling and pain, the carbuncle pyogenic infections from tumour or sore, infantile carbuncle reaches medicine, alimentary toxicosis etc.(the 792nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Zingiberis property of medicine suffering, heat.Return spleen, stomach, the heart, lung meridian.Have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the effect of warm arteries and veins dissipating fluid-retention.Can treat coldness and pain in the epigastrium, vomiting is had loose bowels, and YANG-depletion is fainted contrary, and arthralgia due to cold-dampnes, cold fluid-retention are breathed with cough etc.(the 100th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Tsaoko nature and flavor suffering, temperature.Return spleen, stomach warp.Has the dampness warming middle-JIAO, the effect of expectorant preventing the attack (or recurrence) of malaria.Can treat the cold-damp internal resistance, abdominal distention, feeling of fullness vomiting, malaria cold and heat etc.(the 192nd page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Semen Coicis, Radix Pseudostellariae and the Radix Astragali; With Rhizoma Atractylodis Macrocephalae (parched), Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Pericarpium Citri Reticulatae, Poria, Rhizoma Zingiberis and Fructus Tsaoko is ministerial drug; With Radix Polygalae and Radix Glycyrrhizae is adjuvant.All medicines are harmonious, and are total to the tool replenishing QI to invigorate the spleen, the effect of nourishing YIN and benefiting blood.The treatment diabetic amyotrophy has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic amyotrophy of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic amyotrophy, and the prevention of diabetic amyotrophy is also had good effect, and the treatment diabetic amyotrophy has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic amyotrophy; Treatment diabetic amyotrophy patient 18 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.7 examples of fully recovering account for 38.89%, and 8 examples that take a turn for the better account for 44.44%, and invalid 3 examples account for 16.67%, and total effective rate reaches 83.33%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Radixs Astragali of 3 parts of Radix Pseudostellariaes of Semen Coicis
2 parts of 2 parts of Pericarpium Citri Reticulataes of 2 parts of Radix Angelicae Sinensis of Rhizoma Atractylodis Macrocephalae (parched)
1 part of 2 parts of Radix Polygalae of 2 parts of Poria of Radix Rehmanniae Preparata
1 part of 1 part of Fructus Tsaoko of 1 portion of Rhizoma Zingiberis of Radix Glycyrrhizae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic amyotrophy that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two months is a course of treatment.
Claims (3)
1, a kind of Chinese medicine of treatment diabetic amyotrophy is characterized in that it is made by the following weight proportion raw material:
1.5～6 parts of 1.5～6 parts of Radixs Astragali of 1.5～6 parts of Radix Pseudostellariaes of Semen Coicis
1.0～4 parts of 1.0～4 parts of Pericarpium Citri Reticulataes of 1.0～4 parts of Radix Angelicae Sinensis of Rhizoma Atractylodis Macrocephalae (parched)
0.1～2 part of 1.0～4 parts of Radix Polygalae of 1.0～4 parts of Poria of Radix Rehmanniae Preparata
0.1～2 part of 0.1～2 part of Fructus Tsaoko of 0.1～2 portion of Rhizoma Zingiberis of Radix Glycyrrhizae.
2, a kind of Chinese medicine of treatment diabetic amyotrophy according to claim 1, wherein the weight proportion of each raw material is:
2.5～3.5 parts of 2.5～3.5 parts of Radixs Astragali of 2.5～3.5 parts of Radix Pseudostellariaes of Semen Coicis
1.5～2.5 parts of 1.5～2.5 parts of Pericarpium Citri Reticulataes of 1.5～2.5 parts of Radix Angelicae Sinensis of Rhizoma Atractylodis Macrocephalae (parched)
0.5～1.5 part of 1.5～2.5 parts of Radix Polygalae of 1.5～2.5 parts of Poria of Radix Rehmanniae Preparata
0.5～1.5 part of 0.5～1.5 part of Fructus Tsaoko of 0.5～1.5 portion of Rhizoma Zingiberis of Radix Glycyrrhizae.
3, a kind of Chinese medicine of treatment diabetic amyotrophy according to claim 1, wherein the weight proportion of each raw material is:
3 parts of 3 parts of Radixs Astragali of 3 parts of Radix Pseudostellariaes of Semen Coicis
2 parts of 2 parts of Pericarpium Citri Reticulataes of 2 parts of Radix Angelicae Sinensis of Rhizoma Atractylodis Macrocephalae (parched)
1 part of 2 parts of Radix Polygalae of 2 parts of Poria of Radix Rehmanniae Preparata
1 part of 1 part of Fructus Tsaoko of 1 portion of Rhizoma Zingiberis of Radix Glycyrrhizae.
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| Application Number | Priority Date | Filing Date | Title |
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| CNA200710118357XA CN101095938A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine for treating diabetic ischemic muscular atrophy |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA200710118357XA CN101095938A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine for treating diabetic ischemic muscular atrophy |
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| CNA200710118357XA Pending CN101095938A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine for treating diabetic ischemic muscular atrophy |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101530479B (en) * | 2008-03-13 | 2011-05-11 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetes mellitus and muscle atrophy |
| US20170296603A1 (en) * | 2016-04-14 | 2017-10-19 | Sinphar Tian-Li Pharmaceutical Co., Ltd. Hangzhou | Uses of fu-ling (poria cocos) extract and tumulosic acid in protecting muscles |
| KR20190016486A (en) * | 2016-04-14 | 2019-02-18 | 신파 티엔리 파머슈티컬 컴퍼니 리미티드 (항저우) | Uses of Porcia cocos extract and Tumurous acid in muscle protection |
-
2007
- 2007-07-05 CN CNA200710118357XA patent/CN101095938A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101530479B (en) * | 2008-03-13 | 2011-05-11 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetes mellitus and muscle atrophy |
| US20170296603A1 (en) * | 2016-04-14 | 2017-10-19 | Sinphar Tian-Li Pharmaceutical Co., Ltd. Hangzhou | Uses of fu-ling (poria cocos) extract and tumulosic acid in protecting muscles |
| KR20190016486A (en) * | 2016-04-14 | 2019-02-18 | 신파 티엔리 파머슈티컬 컴퍼니 리미티드 (항저우) | Uses of Porcia cocos extract and Tumurous acid in muscle protection |
| EP3443971A4 (en) * | 2016-04-14 | 2020-01-01 | Sinphar Tian-li Pharmaceutical Co., Ltd. (Hangzhou) | Uses of poria cocos extract and tumulosic acid in protecting muscles |
| KR102147239B1 (en) * | 2016-04-14 | 2020-08-25 | 신파 티엔리 파머슈티컬 컴퍼니 리미티드 (항저우) | Use of Poria Cocos Extract and Tumulosic Acid in Muscle Protection |
| US11369651B2 (en) * | 2016-04-14 | 2022-06-28 | Sinphar Pharmaceutical Co., Ltd. (Dongshan, Taiwan) | Uses of FU-LING (Poria cocos) extract and tumulosic acid in protecting muscles |
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Open date: 20080102 |