CN101095730A - Medicine for treating rheumatism atrophic arthritis - Google Patents

Abstract

The invention discloses a medicament for treating rheumatic and rheumatoid arthritis, wherein the constituents include raw materials of pubescent angelica root, notopterygium root, Sichuan aconite root, Kusnezoff monkshood root, achyranthes and cyathula root, seed of nuxvomica, prepared aconite root, Chinese ephedra, spatholobus stem, Chinese angelica root, asaryl and fenugreek seed.

Description

A kind of medicine for the treatment of rheumatism atrophic arthritis

Technical field

The present invention is a kind of medicine of pure treatment by Chinese herbs rheumatism atrophic arthritis.

Background technology

Rheumatism is a kind of commonly encountered diseases frequently-occurring disease, directly influences osteoarthrosis, muscle and cartilaginous tissue, as diseases such as tendon, fascia, stndon sheaths.Be characterized in the unusual or biochemical change of immunity, the course of disease is chronic, and outbreak repeatedly.Rheumatoid arthritis is that a kind of chronic general is from the immunity disease, main invasion and attack whole body is the joint everywhere, it is multiple and symmetry chronic hyperplastic synovitis, cause the destruction of articular cartilage and joint capsule thus, cause the ankylosis deformity at last, at present this disease is adopted the western medicine means mostly.As: hormone medicines such as ibuprofen, tramadol, though can the respite symptom cure the symptoms, not the disease, side effect such as easy generation dependency and bone structure change are taken in recurrence for a long time easily, are difficult to recover because of obstinate easily causes joint deformity to cause.

Technology contents

The object of the present invention is to provide a kind of medicine for the treatment of rheumatism atrophic arthritis.

The rheumatic and rheumatoid disease traditional Chinese medical science is referred to as " arthromyodynia ".Because wind, wet, cold-evil's gas cut are attacked human body, the impatency meridians are due to QI-blood circulation is smooth.The present invention follows the ultimate principle of Chinese medicine, adopt dispel the wind, purpose that dehumidifying, cold expelling, the way of regulating the flow of vital energy, enriching blood reach treating both the principal and secondary aspects of a disease.

The object of the present invention is to provide a kind of medicine for the treatment of rheumatic and rheumatoid disease.By taking orally based on each flavor synergism, patient's whole body is played the effect of dispelling cold by warming the meridian, expelling wind and removing dampness, collateral dredging passages through which vital energy circulates, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, can make erythrocyte sedimentation rate value, rheumatoid factor and non-fusibility streptostacin O recover normal, and taking convenience, side effect is little.

Medicine of the present invention is characterised in that following recipe ratio forms by weight

Radix Angelicae Pubescentis 1-8 gram Rhizoma Et Radix Notopterygii 1-7 gram Radix Aconiti 1-5 gram Radix Aconiti Kusnezoffii 1-5 gram Radix Achyranthis Bidentatae 1-3 KEMA Semen Strychni 0.3-0.5 gram Radix Aconiti Lateralis Preparata 1-5 gram Herba Ephedrae 1-3 gram Caulis Spatholobi 1-6 gram Radix Angelicae Sinensis 2-6 gram Herba Asari 1-3 gram Semen Trigonellae 1-3 gram.

Override prescription of the present invention is by weight forming

Radix Angelicae Pubescentis 8 gram Rhizoma Et Radix Notopterygiis 4 gram Radix Aconitis 3 gram Radix Aconiti Kusnezoffii 3 gram Radix Achyranthis Bidentataes 2 KEMA Semen Strychni 0.4 gram Radix Aconiti Lateralis Preparata 2 gram Herba Ephedraes 1 gram Caulis Spatholobi 4 gram Radix Angelicae Sinensis 3 gram Herba Asaris 1 gram Semen Trigonellae 3 grams.

The side separates:

Radix Angelicae Pubescentis: the abnormal smells from the patient hero is strong, sweet perfumes are diffused all around, so can declare logical hundred arteries and veins, mediation meridians, lead to muscles and bones and the numbness of sharp joint, all cold-damp heresies in muscle, in the joint person, the non-male strong flavor of this abnormal smells from the patient that utilizes can not go directly between the passages through which vital energy circulates joint, so be the essential medicine of the soft all big diseases of migratory arthralgia flaccidity; Rhizoma Et Radix Notopterygii: the exterior cold of loosing, wind-damp dispelling, sharp joint row is burnt and go up reason, and then urticaria headache Fengshi Guanjie pain can be controlled, and the walk alone part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels and reason down then lie prostrate wind headache, two sufficient arthralgia chiefly caused by damp pathogens can be controlled, and are monarch drug altogether; Radix Aconiti, Radix Aconiti Kusnezoffii: expelling wind and removing dampness, antalgic, be used for that anemofrigid-damp arthralgia arthralgia, sympotoms caused by cold factors are had a pain, narcotic analgesic; Radix Aconiti Lateralis Preparata: recuperating depleted YANG and rescuing the patient from collapse, supporing yang, the expelling cold and dampness of benefit fire, the big heat of this product, cold relieving power is strong, so can control the bone marrow pain of inward invasion of pathogenic cold; Semen Strychni: the meridian dredging, eliminating stagnation swell, relieve the pain bitterly, are applicable to rheumatoid arthritis stubborn, paralysis and numbness, traumatic injury, are that ministerial drug is to help monarch's power altogether; Radix Angelicae Sinensis: tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, moisturize laxation; Caulis Spatholobi: enrich blood invigorate blood circulation, collateral dredging; Semen Trigonellae: the kidney warming cold relieving, pain relieving are used for kidney cold caused by deficiency, cold and pain in the lower abdomen, inguinal hernia, the disturbance of lower legs due to pathogenic cold and dampness; Radix Achyranthis Bidentatae: give birth to diffusing congestion, disappear that pain swells, main cold-damp flaccidity syndrome and arthralgia syndrome, spasm of the limbs, gonalgia can not bend, pursue QI and blood, is adjuvant drug; Herba Asari: expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention, when being messenger drug.

Medicine of the present invention is concocted to learn by the traditional Chinese medical science and is crossed 120 mesh sieves with the grinding machine pulverizing after routine is concocted.Make capsule by stirring after the proportional quantity mixing in the side.Adorn capsule No. 0, every 0.4 gram, every day, supper was taken after one hour, obeyed 6 at every turn.

The rheumatic arthritis diagnostic criteria:

1. based on the big arthralgia of extremity, with tingle wood, inconvenience is bent and stretched in the joint, symptoms such as heating;

2. the part patient can have low grade fever, extremity erythema iris or erythema nodosum, and heart is often got involved;

3. the painful history of pharynx is arranged before the disease or paddle and drench with rain and occupy flush history for a long time;

4. erythrocyte sedimentation rate value (ESR)＞20mm/h antistreptolysin O＞500 μ;

The rheumatoid arthritis diagnostic criteria:

1. morning, stiff uncomfortable sensation surpassed more than one hour;

2. the swelling phenomenon takes place in the joint more than three;

3. carpometacarpal joints or near-end swollen joint;

4. with the swelling phenomenon of upper joint symmetry whether;

5. subcutaneous nodule;

6. the rheumatoid factor (RF) positive;

7. whether the X-ray examination of hand or wrist portion finds to have the erosion (erosion) at bone edge, or the osteoporosis phenomenon of joint periphery;

Must there be six in above 1-4 bar more than week, just can by identification be suffered from rheumatoid arthritis more than 4 if meet by patient of this standard in 7.

The clinical treatment standard:

1. clinical cure: symptom all disappears, functional rehabilitation is normal;

2. produce effects: symptomatology disappears or cardinal symptom is eliminated, and function of joint is recovered substantially, can participate in operate as normal;

3. effective: cardinal symptom is eliminated substantially, and main function of joint is recovered substantially or had clear improvement;

4. invalid: as all not have improvement with the each side of comparing before the treatment;

Therapeutic effect can be referring to data statistic, all ages and classes clinical data statistics.

All ages and classes clinical data statistical table

Age	The case number	Cure	Produce effects	Effectively	Invalid
						15-30	60	43	9	8	0
31-45	82	48	22	12	0
						46-60	121	61	36	20	4
Add up to	263	152	67	40	4
						Effective percentage		57.79％	25.48％	15.2％	1.5％

By above clinical data as seen, the advantage of medicine of the present invention is treating both the principal and secondary aspects of a disease, can alleviate the elimination symptom after taking medicine, and two-ways regulation body equilibrium between yin and yang, enhancing human body immunity function and repair function are dispeled rheumatism, have to alleviate and the healing effect, and be difficult for recurrence, taking convenience, side effect is little.

Model case:

1 xx woman, 28 years old, the Shijiazhuang City Yuhua District was talked solid sub-district, and the whole body arthralgia was shown effect 8 years repeatedly, and limbs are heavy, and rise stiff morning, and the joint joint stuffiness is met cold rnning and is weighed.Chemical examination erythrocyte sedimentation rate 60mm/h.Anti-" O " 600 units, rheumatoid factor negative.Clinical diagnosis: rheumatic arthritis, card belongs to arthralgia due to cold-dampness.The medicine of taking the present invention's " rheumatic and rheumatoid " is after 30 days, and arthralgia alleviates, take three months continuously after, play the disappearance of stiff all disease in arthralgia, morning, functional rehabilitation, laboratory indexes is normally.

2 Lee xx men, 58 years old, people from Xingtang County, Hebei province.Suffered from rheumatoid arthritis 9 years, extremities joint pain refers to the toe distortion, and limitation of activity is very painful.The erythrocyte sedimentation rate 80mm/h rheumatoid factor positive on inspection.Introduce me to treat through the ward mate, take medicine of the present invention after two months, symptom obviously alleviates, and continues treatment after two months, and erythrocyte sedimentation rate, rheumatoid factor recover normal.The whole body arthralgia is eliminated, and activity and can be taken part in the work freely.Follow up a case by regular visits to and do not see recurrence in 3 years.

3 xx woman Zhao, 42 years old, the Zhengding County people of Hebei province.Suffer from rheumatoid arthritis .12.Main suit's arthralgia, swelling, the numb whole body migration of muscle pain, finger-joint distortion when examining, getting up early is stiff serious morning, and activity to the afternoon symptom of getting up could be alleviated.Chemical examination erythrocyte sedimentation rate 50mm/h, the rheumatoid factor positive.Clinical diagnosis: rheumatoid arthritis, take medicine of the present invention after four courses of treatment, arthralgia, numbness, morning, stiff symptom all disappeared greatly.The rheumatoid factor chemical examination, feminine gender.Reach and take a course of treatment again after the clinical cure standard and consolidated.Pay a return visit, so far not recurrence.

The specific embodiment

Embodiment one

Medicine material composition and proportioning that the present invention treats rheumatic and rheumatoid are as follows

Radix Angelicae Pubescentis 1-8 gram Rhizoma Et Radix Notopterygii 1-7 gram Radix Aconiti 1-5 gram Radix Aconiti Kusnezoffii 1-5 gram Radix Achyranthis Bidentatae 1-3 KEMA Semen Strychni 0.3-0.5 gram Radix Aconiti Lateralis Preparata 1-5 gram Herba Ephedrae 1-3 gram Caulis Spatholobi 1-6 gram Radix Angelicae Sinensis 2-6 gram Herba Asari 1-3 gram Semen Trigonellae 1-3 gram.After using the grinding machine pulverizing, the back crosses 120 mesh sieves by conventional process of preparing Chinese medicine of the science of Chinese drug processing.Stir after mixing by weight ratio and make pill, capsule.

Embodiment two

Radix Angelicae Pubescentis 3 gram Rhizoma Et Radix Notopterygiis 1 gram Radix Aconiti 1 gram Radix Aconiti Kusnezoffii 2 gram Radix Achyranthis Bidentataes 1 KEMA Semen Strychni 0.3 gram Radix Aconiti Lateralis Preparata 1 gram Herba Ephedrae 1 gram Caulis Spatholobi 3 gram Radix Angelicae Sinensis 2 gram Herba Asaris 1 gram Semen Trigonellae 1 gram.After using the grinding machine pulverizing, the back crosses 120 mesh sieves by conventional process of preparing Chinese medicine of the science of Chinese drug processing.Stir after mixing by weight ratio and make pill, capsule.

Embodiment three

Radix Angelicae Pubescentis 5 gram Rhizoma Et Radix Notopterygiis 3 gram Radix Aconitis 3 gram Radix Aconiti Kusnezoffii 1 gram Radix Achyranthis Bidentatae 2 KEMA Semen Strychni 0.4 gram Radix Aconiti Lateralis Preparata 3 gram Herba Ephedraes 2 gram Caulis Spatholobis 1 gram Radix Angelicae Sinensis 3 gram Herba Asaris 1.5 gram Semen Trigonellaes 1.5 grams.After using the grinding machine pulverizing, the back crosses 120 mesh sieves by conventional process of preparing Chinese medicine of the science of Chinese drug processing.Stir after mixing by weight ratio and make pill, capsule.

Embodiment four

Radix Angelicae Pubescentis 1 gram Rhizoma Et Radix Notopterygii 2 gram Radix Aconitis 2 gram Radix Aconiti Kusnezoffii 3 gram Radix Achyranthis Bidentataes 1.5 KEMA Semen Strychni 0.4 gram Radix Aconiti Lateralis Preparata 4 gram Herba Ephedraes 1.5 gram Caulis Spatholobis 2 gram Radix Angelicae Sinensis 4 gram Herba Asaris 2 gram Semen Trigonellaes 2 grams.After using the grinding machine pulverizing, the back crosses 120 mesh sieves by conventional process of preparing Chinese medicine of the science of Chinese drug processing.Stir after mixing by weight ratio and make pill, capsule.

Embodiment five

Radix Angelicae Pubescentis 6 gram Rhizoma Et Radix Notopterygiis 5 gram Radix Aconitis 4 gram Radix Aconiti Kusnezoffii 4 gram Radix Achyranthis Bidentataes 3 KEMA Semen Strychni 0.5 gram Radix Aconiti Lateralis Preparata 5 gram Herba Ephedraes 3 gram Caulis Spatholobis 4 gram Radix Angelicae Sinensis 5 gram Herba Asaris 2.5 gram Semen Trigonellaes 3 grams.After using the grinding machine pulverizing, the back crosses 120 mesh sieves by conventional process of preparing Chinese medicine of the science of Chinese drug processing.Stir after mixing by weight ratio and make pill, capsule.

Embodiment six

Radix Angelicae Pubescentis 8 gram Rhizoma Et Radix Notopterygiis 7 gram Radix Aconitis 5 gram Radix Aconiti Kusnezoffii 5 gram Radix Achyranthis Bidentataes 5 KEMA Semen Strychni 0.35 gram Radix Aconiti Lateralis Preparata 2 gram Herba Ephedraes 2.5 gram Caulis Spatholobis 6 gram Radix Angelicae Sinensis 6 gram Herba Asaris 3 gram Semen Trigonellaes 2.5 grams.After using the grinding machine pulverizing, the back crosses 120 mesh sieves by conventional process of preparing Chinese medicine of the science of Chinese drug processing.Stir after mixing by weight ratio and make pill, capsule.

Claims (3)

1 one kinds of medicines for the treatment of rheumatism atrophic arthritis is characterized in that comprising in the raw material: Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Achyranthis Bidentatae, Semen Strychni, Radix Aconiti Lateralis Preparata, Herba Ephedrae, Caulis Spatholobi, Radix Angelicae Sinensis, Herba Asari, Semen Trigonellae.

2 one kinds of medicines for the treatment of rheumatism atrophic arthritis is characterized in that prescription is by weight than composition.Radix Angelicae Pubescentis 1-8 gram Rhizoma Et Radix Notopterygii 1-7 gram Radix Aconiti 1-5 gram Radix Aconiti Kusnezoffii 1-5 gram Radix Achyranthis Bidentatae 1-5 KEMA Semen Strychni 0.1-0.5 gram Radix Aconiti Lateralis Preparata 1-5 gram Herba Ephedrae 1-3 gram Caulis Spatholobi 1-6 gram Radix Angelicae Sinensis 2-6 gram Herba Asari 1-3 gram Semen Trigonellae 1-3 gram.Cross 120 mesh sieves by the conventional back of concocting of the science of Chinese drug processing with the grinding machine pulverizing.

3 medicines according to claim 1,2 described treatment rheumatism atrophic arthritis it is characterized in that ground medicated powder by formulation weight make pill than stirring after mixing, capsule is for oral administration.Took in 1 hour after the every day supper.