CN101028491B - Chinese-medicinal preparation for treating ribbon bleb - Google Patents
Chinese-medicinal preparation for treating ribbon bleb Download PDFInfo
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- CN101028491B CN101028491B CN2007100654797A CN200710065479A CN101028491B CN 101028491 B CN101028491 B CN 101028491B CN 2007100654797 A CN2007100654797 A CN 2007100654797A CN 200710065479 A CN200710065479 A CN 200710065479A CN 101028491 B CN101028491 B CN 101028491B
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- herpes zoster
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Abstract
A Chinese medicine for treating herpes zoster is prepared from more than 11 Chinese-medicinal materials including Chinese gentian, bupleum root, isatis leaf, rehmannia root, etc.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of herpes zoster, is that a kind of herpes zoster for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Herpes zoster is a kind of caused by varicella zoster virus, involves the acute herpetic viral dermatosis of neural and skin.Clinical manifestation is zonal distribution with a bunch collection property vesicle along health one side peripheral nerve, and accompanying remarkable neuralgia is feature.Can betide any age, be more common in person between twenty and fifty.Herpes zoster belongs to categories such as Chinese medicine " herpes zoster ", " herpes zoster ", " herpes zoster ", " herpes zoster ", " herpes zoster ".
Chinese medicine thinks that primary disease is that impression poison is evil, and wet, heat, wind, fire stagnation be in the heart, liver, lung, spleen, the meridians obstruct, and coagulation of QI-blood forms.Feelings will internal injury, conscience heat resulting from stagnation of QI, heat stagnation for a long time and fire-transformation intimately overflows in the flesh table are fled meridians, feel wind, pathogenic fire poison again, make the QI and blood closing, then disease such as show speckle, papulovesicle, the pain of itching; Dysfunction of the spleen in transportation and give birth to wetly, spleen is wet to be pented up and heat-transformation, and the damp and hot outer skin of sending out is felt damp and hot evil poison again, a surname of lung is sent out, respectfully fall, control the joint dysfunction, causes water liquid and follows meridians and close and gather in the flesh table, and then the water breakthrough bleb is innumerable as pearl; The evil poison of damp and hot wind-fire, the damage meridians are not declared through gas, qi depression to blood stasis, stagnation of QI and blood may bring about pain, often cause pain endlessly or twinge continuous.Therefore, the Chinese traditional treatment herpes zoster is divided into: ascites of liver meridian damp-heat type; Spleen and stomach damp-heat type; Dialectical treatment such as qi stagnation and blood stasis type obtains better curative effect, and does not recur.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of herpes zoster.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
0.1～2 part of 1.5～6 parts of vinegar Rhizoma Corydalis of 0.1～2 part of Radix Rehmanniae of Radix Gentianae
1～4 part of 1.5～6 parts of Semen Coicis of 1～4 portion of Herba Portulacae of Radix Bupleuri (processed with vinegar)
0.1～1 part of 1～4 part of raw sangqi ginseng of 1.5～6 parts of Cortex Moutans of Folium Isatidis
0.1～2 part of 1～4 portion of Radix Curcumae of Rhizoma Alismatis (processeded with salt)
The weight proportion of each raw material of optimization formula of the present invention is:
0.5～1.5 part of 2.5～3.5 parts of vinegar Rhizoma Corydalis of 0.5～1.5 part of Radix Rehmanniae of Radix Gentianae
1.5～2.5 parts of 2.5～3.5 parts of Semen Coicis of 1.5～2.5 portions of Herba Portulacaes of Radix Bupleuri (processed with vinegar)
0.3～0.7 part of 1.5～2.5 parts of raw sangqi ginseng of 2.5～3.5 parts of Cortex Moutans of Folium Isatidis
0.5～1.5 part of 1.5～2.5 portions of Radix Curcumae of Rhizoma Alismatis (processeded with salt)
The weight proportion of each raw material of optimum formula of the present invention is:
1 part of 3 parts of vinegar Rhizoma Corydalis of 1 part of Radix Rehmanniae of Radix Gentianae
2 parts of 3 parts of Semen Coicis of 2 portions of Herba Portulacaes of Radix Bupleuri (processed with vinegar)
0.5 part of 2 parts of raw sangqi ginseng of 3 parts of Cortex Moutans of Folium Isatidis
1 part of 2 portions of Radix Curcumae of Rhizoma Alismatis (processeded with salt)
Drug action mechanism among the present invention is as follows:
Radix Gentianae nature and flavor hardship, cold.Return liver, gallbladder meridian.Have eliminating pathogen in the liver gallbladder fire, the clear part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is wet, relieving convulsion making eye bright, and the malaria protozoon is good for the stomach, the effect that protects the liver.Can treat that Liver Channel intenseness of heat, infantile convulsion are manic, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, the swollen skin infection of pain, scrotum swell and ache, pudendum pruritus due to damp pathogen, hypertension dizziness tinnitus, chest and hypochondrium, acute infectious hepatitis, cystitis, skin infection swell and ache etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 413rd page).
Radix Bupleuri (processed with vinegar) nature and flavor hardship, be slightly cold.Return liver, gallbladder meridian.Effect with reconciling superficies and interior, soothing the liver, yang invigorating.Can treat alternate attack of chill and fever, fullness in the chest and hypochondriac pain, deafness, headache and dizziness, malaria, dysentery proctoptosis, menoxenia, uterine prolapse, flu, upper respiratory tract infection, hepatitis, cholecystitis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1004th page).
Folium Isatidis nature and flavor hardship, cold.Return liver, the heart, stomach warp.Has heat-clearing and toxic substances removing, the effect of blood cooling and ecchymoses removing.Can treat epidemic febrile disease intenseness of heat excessive thirst, send out the speckle dermexanthesis, unconsciousness due to high fever, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, hematemesis and epistaxis, jaundice, laryngopharynx swelling and pain, sore throat, mumps, aphtha, swollen ulcer drug, mumps, epidemic cerebrospinal meningitis, epidemic encephalitis type B, upper respiratory tract infection, ancylostome, dermatitis, pyrexia of unknown origin, leptospira is separated lead poisoning etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 129th page).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Herba Portulacae nature and flavor acid, cold.Return liver, large intestine channel.Has heat-clearing and toxic substances removing, the effect of cooling blood for hemostasis.Can treat toxic-heat and blood stasis, the carbuncle furuncle, eczema, erysipelas, snake bite and insect sting is had blood in stool, hemorrhoidal bleeding, metrostaxis etc.(the 37th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Vinegar Rhizoma Corydalis nature and flavor suffering, hardship, wet.Return liver, spleen channel.Have and invigorate blood circulation, promoting the circulation of QI, analgesic effect.Can treat the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, treating swelling and pain by traumatic injury etc. (Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 680th page).
Cortex Moutan nature and flavor hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, the amenorrhea dysmenorrhea, carbuncle sore tumefacting virus falls and pounces on the pain of injury etc.(the 137th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Semen Coicis nature and flavor are sweet, light, cool.Return spleen, stomach, lung meridian.Has the spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, the effect of clearing away heat and discharging pus.Can treat edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana etc.(the 309th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The Rhizoma Alismatis (processeded with salt) nature and flavor are sweet, cold.Return kidney, urinary bladder channel.Has diuresis, the effect of clearing away damp-heat.Can treat dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia etc.(the 184th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Sweet, the little hardship of raw sangqi ginseng nature and flavor, temperature.Return liver, stomach, large intestine channel.Has the dissipating blood stasis hemostasis, the effect of subduing swelling and relieving pain.Can treat haematemesis, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia, lump in the abdomen, puerperal blood faints, retention of lochia, traumatic hemorrhage, breast ventral spine pain, fall and pounce on blood stasis, carbuncle pain, acute pharyngolaryngitis, Light-headedness, tinnitus, coronary heart disease, angina pectoris, acute necrosis sections enteritis, venom, bee sting, rheumatic arthritis disease, hypertension etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 60th page).
Radix Curcumae nature and flavor suffering, hardship, cold.Return liver, the heart, lung meridian.Has regulating qi to disperse stagnation, heart fire-clearing upset-relieving, the effect of promoting the function of the gallbladder to alleviate jaundice.Can treat the amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, the calentura coma, epilepsy is gone mad, jaundice dark coloured urine etc.(the 167th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Gentianae, Radix Bupleuri (processed with vinegar), Folium Isatidis, Radix Rehmanniae and Herba Portulacae; With vinegar Rhizoma Corydalis, Cortex Moutan, Semen Coicis and Rhizoma Alismatis (processeded with salt) is ministerial drug; With raw sangqi ginseng and Radix Curcumae is adjuvant.All medicines are harmonious, altogether the effect of tool heat-clearing and toxic substances removing, removing obstruction in the collateral to relieve pain.The treatment herpes zoster has determined curative effect, has no side effect taking convenience, cheap characteristics.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet, granule, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.
Preparation of the present invention, preferably peroral dosage form is as tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment herpes zoster of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention treats herpes zoster and has determined curative effect, has no side effect taking convenience, cheap characteristics.
Further specify the therapeutic effect of medicine of the present invention below by the clinical practice example to the treatment herpes zoster.
The diagnosis basis of herpes zoster: 1, skin lesion mostly is the vesicle of Semen phaseoli radiati size, bunch integrated group, and tonic vesicle wall, base coat colour is red, and normal one-sided distribution is arranged in band shape.The severe patient skin lesion can show as hemorrhagic, or visible gangrene infringement.Skin lesion is sent out the person in women's head-ornaments portion, and the state of an illness is often heavier.2, before erythra occurs, skin irritation or burn feeling are often arranged earlier, can be slight uncomfortable with the whole body, heating.3, conscious pain is obvious, and insufferable severe pain can be arranged, or loses pain after the deflorescence.(the 834th page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen)
Herpes zoster efficacy assessment standard: 1, cure: deflorescence, clinical sign disappears, no pain sequela.2, take a turn for the better: deflorescence is about 30%, and pain obviously alleviates.3, do not heal: deflorescence less than 30% still has pain.(the 837th page of chief editor's " traditional Chinese medical science disease diagnosis and treatment standard and prescription are selected for use " People's Health Publisher's calendar year 2001 version such as Dai Shen)
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment herpes zoster; Treatment herpes zoster patient 61 examples.Take embodiment 3 granules, each 1～3 bag, three to four times on the one, boiled water is taken after mixing it with water, and take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Cure 52 examples and account for 85.24%, 6 examples that take a turn for the better account for 9.84%, and more 3 examples do not account for 4.92%, and total effective rate reaches more than 95%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule takes by weighing raw material by following weight:
1 part of 3 parts of vinegar Rhizoma Corydalis of 1 part of Radix Rehmanniae of Radix Gentianae
2 parts of 3 parts of Semen Coicis of 2 portions of Herba Portulacaes of Radix Bupleuri (processed with vinegar)
0.5 part of 2 parts of raw sangqi ginseng of 3 parts of Cortex Moutans of Folium Isatidis
1 part of 2 portions of Radix Curcumae of Rhizoma Alismatis (processeded with salt)
Preparation method is to get raw sangqi ginseng drying and crushing to 120～200 order fine powders earlier, get Radix Gentianae again, Radix Rehmanniae, the vinegar Rhizoma Corydalis, Radix Bupleuri (processed with vinegar), Herba Portulacae, Semen Coicis, Folium Isatidis, Cortex Moutan, Rhizoma Alismatis (processeded with salt), Radix Curcumae decocts with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and raw sangqi ginseng fine powder mixing, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, one month is a course of treatment.
Embodiment 2 tablets take by weighing raw material by following weight:
1 part of 3 parts of vinegar Rhizoma Corydalis of 1 part of Radix Rehmanniae of Radix Gentianae
2 parts of 3 parts of Semen Coicis of 2 portions of Herba Portulacaes of Radix Bupleuri (processed with vinegar)
0.5 part of 2 parts of raw sangqi ginseng of 3 parts of Cortex Moutans of Folium Isatidis
1 part of 2 portions of Radix Curcumae of Rhizoma Alismatis (processeded with salt)
Preparation method is to get raw sangqi ginseng drying and crushing to 120～200 order fine powders earlier, get Radix Gentianae again, Radix Rehmanniae, the vinegar Rhizoma Corydalis, Radix Bupleuri (processed with vinegar), Herba Portulacae, Semen Coicis, Folium Isatidis, Cortex Moutan, Rhizoma Alismatis (processeded with salt), Radix Curcumae decocts with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree～55 are spent, be concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and raw sangqi ginseng fine powder mixing, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2～10, three to four times on the one, one month is a course of treatment.
Embodiment 3 granules take by weighing raw material by following weight:
1 part of 3 parts of vinegar Rhizoma Corydalis of 1 part of Radix Rehmanniae of Radix Gentianae
2 parts of 3 parts of Semen Coicis of 2 portions of Herba Portulacaes of Radix Bupleuri (processed with vinegar)
0.5 part of 2 parts of raw sangqi ginseng of 3 parts of Cortex Moutans of Folium Isatidis
1 part of 2 portions of Radix Curcumae of Rhizoma Alismatis (processeded with salt)
Preparation method is to get raw sangqi ginseng drying and crushing to 120～200 order fine powders earlier, get Radix Gentianae again, Radix Rehmanniae, the vinegar Rhizoma Corydalis, Radix Bupleuri (processed with vinegar), Herba Portulacae, Semen Coicis, Folium Isatidis, Cortex Moutan, Rhizoma Alismatis (processeded with salt), Radix Curcumae decocts with water twice, 1.5～2 hours for the first time, 0.5～1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree～85 when spending, the clear paste of relative density 1.08～1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree～55 are concentrated into the clear paste of relative density 1.30～1.32, again with clear paste and raw sangqi ginseng fine powder mixing, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1～3 bag, three to four times on the one, one month is a course of treatment.
Claims (3)
1. Chinese medicine preparation for the treatment of herpes zoster is characterized in that it is made by following raw materials by weight proportions:
0.1～2 part of 1.5～6 parts of vinegar Rhizoma Corydalis of 0.1～2 part of Radix Rehmanniae of Radix Gentianae
1～4 part of 1.5～6 parts of Semen Coicis of 1～4 portion of Herba Portulacae of Radix Bupleuri (processed with vinegar)
0.1～1 part of 1～4 part of raw sangqi ginseng of 1.5～6 parts of Cortex Moutans of Folium Isatidis
0.1～2 part of 1～4 portion of Radix Curcumae of Rhizoma Alismatis (processeded with salt).
2. a kind of Chinese medicine preparation for the treatment of herpes zoster according to claim 1, wherein the weight proportion of each crude drug is:
0.5～1.5 part of 2.5～3.5 parts of vinegar Rhizoma Corydalis of 0.5～1.5 part of Radix Rehmanniae of Radix Gentianae
1.5～2.5 parts of 2.5～3.5 parts of Semen Coicis of 1.5～2.5 portions of Herba Portulacaes of Radix Bupleuri (processed with vinegar)
0.3～0.7 part of 1.5～2.5 parts of raw sangqi ginseng of 2.5～3.5 parts of Cortex Moutans of Folium Isatidis
0.5～1.5 part of 1.5～2.5 portions of Radix Curcumae of Rhizoma Alismatis (processeded with salt).
3. a kind of Chinese medicine preparation for the treatment of herpes zoster according to claim 1, wherein the weight proportion of each crude drug is:
1 part of 3 parts of vinegar Rhizoma Corydalis of 1 part of Radix Rehmanniae of Radix Gentianae
2 parts of 3 parts of Semen Coicis of 2 portions of Herba Portulacaes of Radix Bupleuri (processed with vinegar)
0.5 part of 2 parts of raw sangqi ginseng of 3 parts of Cortex Moutans of Folium Isatidis
1 part of 2 portions of Radix Curcumae of Rhizoma Alismatis (processeded with salt).
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| CN101306186B (en) * | 2008-06-10 | 2011-09-21 | 叶明伟 | Traditional Chinese medicine taken orally for treating Qi stagnation and blood stasis type zoster |
| CN103070892A (en) * | 2013-01-10 | 2013-05-01 | 济南康众医药科技开发有限公司 | Application of freeze-dried purslane in preparing drug for treating herpes zoster |
| CN105902715A (en) * | 2016-07-13 | 2016-08-31 | 王云龙 | Externally applied traditional Chinese medicine for treating herpes zoster |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1461649A (en) * | 2002-05-28 | 2003-12-17 | 杨毓龙 | Medicine for treating herpes zoster |
| CN1836715A (en) * | 2005-03-26 | 2006-09-27 | 李有凤 | External use medicine for quickly treating herpes zoster |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1461649A (en) * | 2002-05-28 | 2003-12-17 | 杨毓龙 | Medicine for treating herpes zoster |
| CN1836715A (en) * | 2005-03-26 | 2006-09-27 | 李有凤 | External use medicine for quickly treating herpes zoster |
Non-Patent Citations (2)
| Title |
|---|
| 覃洁萍，张广征等.三七不同炮制品中皂苷类成分的测定.中草药37 8.2006,37(8),第1175页第1栏第1段. |
| 覃洁萍，张广征等.三七不同炮制品中皂苷类成分的测定.中草药37 8.2006,37(8),第1175页第1栏第1段. * |
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