CN100560111C - A health product for reducing blood fat - Google Patents
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Abstract
本发明涉及一种降血脂的保健品,它是以茵陈、首乌藤、菟丝子和藿香等中草药为原料。本发明具有清热化湿,行气消滞的功效。本发明是在传统的中医辨证治疗的基础上结合现代最新科研成果研制而成的。本发明的目的是提供一种降血脂的保健品。具有疗效确切、安全方便、无毒副作用、价格低廉的特点。The invention relates to a health product for lowering blood fat, which uses Chinese herbal medicines such as capillary wormwood, shouwu vine, dodder seed and wrinkled ager as raw materials. The invention has the effects of clearing heat and removing dampness, promoting qi and eliminating stagnation. The present invention is developed on the basis of traditional Chinese medicine syndrome differentiation and treatment combined with the latest modern scientific research achievements. The purpose of the present invention is to provide a health product for lowering blood fat. It has the characteristics of definite curative effect, safety and convenience, no toxic and side effects, and low price.
Description
技术领域 technical field
本发明涉及一种降血脂的保健品,是一种降血脂的保健品以中草药为原料的保健品。属于保健品领域。The invention relates to a health product for lowering blood fat, which is a health product made of Chinese herbal medicine. It belongs to the field of health products.
背景技术 Background technique
血脂是血浆或血清中脂类的总称,主要有胆固醇、甘油三酯、磷酯、游离脂肪酸等,血中的脂类含量超过正常浓度称为高脂血症。由于血浆脂质为脂溶性物质,在血液中与蛋白质结合,成为水溶性的复合物才能运转全身,所以又称高脂蛋白血症。Blood lipid is the general term for lipids in plasma or serum, mainly including cholesterol, triglycerides, phospholipids, free fatty acids, etc. The lipid content in blood exceeds the normal concentration and is called hyperlipidemia. Because plasma lipids are fat-soluble substances, they combine with proteins in the blood and become water-soluble complexes to circulate throughout the body, so it is also called hyperlipoproteinemia.
我国人群中血脂胆固醇平均值有显著上升趋势,其原因和生活水平膳食营养成分高低的差别有关。男性高于女性,大城市居民较高,农民、渔民较低。总体说来,与欧美等西方人群相比仍然属于较低水平。随着人民生活水平的提高,一些不正常生活方式,如高糖、高动物脂肪膳食、不或少运动、吸烟、大量饮酒、体重增加等,是引起血脂代谢异常的重要基础,也是造成冠心病的一些危险因素。目前,治疗高脂血症的药物很多,但人们随着生活水平的提高,预防重于治疗的观念越来越强,所以发明一种降血脂的保健品具有及其重大的意义。The average value of blood lipids and cholesterol in the Chinese population has a significant upward trend, which is related to the difference in the nutritional content of the standard of living diet. Males are higher than females, residents of big cities are higher, farmers and fishermen are lower. Generally speaking, compared with Western populations such as Europe and the United States, it is still at a lower level. With the improvement of people's living standards, some abnormal lifestyles, such as high sugar, high animal fat diet, no or less exercise, smoking, heavy drinking, weight gain, etc., are the important basis for abnormal blood lipid metabolism and coronary heart disease. some risk factors. At present, there are many medicines for treating hyperlipidemia, but with the improvement of people's living standards, the concept that prevention is more important than treatment is getting stronger and stronger, so it is of great significance to invent a kind of health product for reducing blood fat.
发明内容 Contents of the invention
本发明是在传统的中医辨证治疗的基础上结合现代最新科研成果研制而成的。本发明的目的是提供一种降血脂的保健品,且具有疗效确切、安全方便、无副作用、价格低廉的特点。The present invention is developed on the basis of traditional Chinese medicine syndrome differentiation and treatment combined with the latest modern scientific research achievements. The purpose of the present invention is to provide a health care product for reducing blood fat, which has the characteristics of definite curative effect, safety and convenience, no side effects and low price.
本发明是由下述重量配比的原料制成的:The present invention is made up of the raw material of following weight ratio:
茵陈2.5~10份 泽泻2.5~10份 熟大黄1.5~6份2.5-10 parts of capillary, 2.5-10 parts of Alisma, 1.5-6 parts of cooked rhubarb
栀子1.5~6份 荷叶1.5~6份 首乌藤1.5~6份1.5-6 parts of gardenia 1.5-6 parts of lotus leaf 1.5-6 parts of Shouwu vine
藿香1.5~6份 山楂0.1~2份 炙甘草0.1~2份Huoxiang 1.5~6 parts Hawthorn 0.1~2 parts Roasted licorice 0.1~2 parts
本发明的优选配方各原料的重量配比是:The weight proportion of each raw material of preferred formula of the present invention is:
茵陈3.0~7.0份 泽泻3.0~7.0份 熟大黄2.5~3.5份Capillary 3.0~7.0 parts Alisma 3.0~7.0 parts Cooked rhubarb 2.5~3.5 parts
栀子2.5~3.5份 荷叶2.5~3.5份 首乌藤2.5~3.5份2.5-3.5 parts of gardenia 2.5-3.5 parts of lotus leaf 2.5-3.5 parts of Shouwu vine
藿香2.5~3.5份 山楂0.5~1.5份 炙甘草0.5~1.5份Huoxiang 2.5-3.5 parts Hawthorn 0.5-1.5 parts Sunburned licorice 0.5-1.5 parts
本发明的最佳配方各原料的重量配比是:The weight proportion of each raw material of optimum formula of the present invention is:
茵陈5份 泽泻5份 熟大黄3份5 parts capillary, 5 parts Alisma, 3 parts cooked rhubarb
栀子3份 荷叶3份 首乌藤3份3 parts of gardenia 3 parts of lotus leaf 3 parts of Shouwu vine
藿香3份 山楂1份 炙甘草1份3 parts Huoxiang 1 part Hawthorn 1 part Roasted Licorice
本发明中的药物机理如下:Drug mechanism among the present invention is as follows:
茵陈性味苦、辛,微寒。归脾、胃、肝、胆经。具有清湿热,退黄疸的功效。可治疗黄疸尿少,湿疮瘙痒;传染性黄疸型肝炎等。(国家药典委员会编《中华人民共和国药典》2000年版一部第192页化学工业出版社)。Yin Chen nature and flavor are bitter, pungent, slightly cold. Return spleen, stomach, liver, gall bladder channel. It has the effect of clearing damp heat and reducing jaundice. It can treat jaundice, oliguria, eczema and itching; infectious jaundice hepatitis, etc. (National Pharmacopoeia Committee edited "Pharmacopoeia of the People's Republic of China" 2000 edition one page 192 Chemical Industry Press).
泽泻性味甘、寒。归肾、膀胱经。具有利小便,清湿热的功效。可治疗小便不利,水肿胀满,泄泻尿少,痰饮眩晕,热淋涩痛;高血脂等。(国家药典委员会编《中华人民共和国药典》2000年版一部第184页化学工业出版社)。Alisma is sweet and cold in nature and flavor. Return kidney, urinary bladder channel. It has the effect of diuresis and clearing away dampness and heat. It can treat dysuria, edema and fullness, diarrhea and oliguria, dizziness due to phlegm and retention, hot stranguria and astringent pain; hyperlipidemia, etc. (National Pharmacopoeia Committee edited "Pharmacopoeia of the People's Republic of China" 2000 edition one page 184 Chemical Industry Press).
熟大黄药性苦,寒。归胃、大肠、肝、脾经。具有攻积滞,清湿热,泻火,凉血,祛瘀,解毒的功效。可治疗食积便秘,热结胸痞;湿热泻痢,黄疸,淋病,水肿腹满,小便不利;目赤,咽喉肿痛,口舌生疮,胃热呕吐;吐血,咯血,衄血,便血,尿血;蓄血,经闭,产后瘀滞腹痛,癥瘕积聚,跌打损伤;热毒痈疡,丹毒,烫伤等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第141页)。Ripe rhubarb is bitter and cold in nature. Return stomach, large intestine, liver, spleen channel. It has the effects of attacking accumulated stagnation, clearing damp-heat, purging fire, cooling blood, removing blood stasis, and detoxifying. It can treat food accumulation, constipation, hot knot in the chest, damp-heat diarrhea, jaundice, gonorrhea, edema, abdominal fullness, dysuria; red eyes, sore throat, sore mouth and tongue, stomach heat and vomiting; hematemesis, hemoptysis, epistaxis, blood in the stool, hematuria ; blood accumulation, amenorrhea, postpartum stasis and abdominal pain, accumulation of lumps, bruises; pyretic carbuncle, erysipelas, burns, etc. ("Dictionary of Chinese Medicine" edited by Nanjing University of Traditional Chinese Medicine, Shanghai Science and Technology Press Second Edition, page 141).
栀子药性苦,寒。归心、肝、肺、胃、三焦经。具有泻火除烦,清热利湿,凉血解毒的功效。可治疗热病心烦,肝火目赤,头痛,湿热黄疸,淋症,吐血,衄血,血痢,尿血,口舌生疮,疮疡肿毒,扭伤肿痛等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第2242页)。Gardenia is bitter in nature and cold in nature. Guixin, Liver, Lung, Stomach, Sanjiao Meridian. It has the effects of purging fire and relieving restlessness, clearing heat and promoting dampness, cooling blood and detoxifying. It can treat fever and upset, liver fire and red eyes, headache, damp-heat jaundice, gonorrhea, hematemesis, epistaxis, bloody dysentery, hematuria, sore mouth and tongue, sore swelling, sprain, swelling and pain. ("Dictionary of Chinese Medicine" edited by Nanjing University of Traditional Chinese Medicine Shanghai Science and Technology Press second edition page 2242).
荷叶药性苦、涩,平。归心、肝、脾经。具有清热解暑,升阳,止血的功效。可治疗暑热烦渴,头痛眩晕,脾虚腹胀,大便泄泻,吐血下血,产后恶露不净,赤游火丹等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第2510页)。Lotus leaf medicinal property is bitter, puckery, flat. GUIXIN, liver, spleen channel. It has the effects of clearing away heat and relieving heat, promoting yang and stopping bleeding. It can treat heat and thirst, headache and dizziness, spleen deficiency and abdominal distension, stool and diarrhea, hematemesis and bleeding, postpartum lochia, Chiyou Huo Dan, etc. ("Dictionary of Traditional Chinese Medicine" edited by Nanjing University of Traditional Chinese Medicine Shanghai Science and Technology Press second edition page 2510).
首乌藤性味甘,平。有养血安神,祛风通络的功效。可治疗失眠多梦,血虚身痛,风湿痹痛;外治皮肤瘙痒。有降低血清胆固醇作用。(党毅肖颖等主编《中药保健食品研制与开发》人民卫生出版社第190页)。Shouwu Teng nature and flavor are sweet, flat. It has the effects of nourishing blood and calming the nerves, dispelling wind and dredging collaterals. It can treat insomnia and dreaminess, blood deficiency and body pain, rheumatic arthralgia; external treatment of skin itching. It has the effect of lowering serum cholesterol. (Dang Yi, Xiaoying and other chief editors "Research and Development of Chinese Medicine Health Food" People's Health Publishing House, page 190).
藿香药性辛,微温。归肺、脾、胃经。具有祛暑解表,化湿和胃的功效。可治疗夏令感冒,寒热头痛,胸脘痞闷,呕吐泄泻,妊娠呕吐,鼻渊,手、足癣等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第3828页)。Huoxiang medicinal property is acrid, tepor. Return lung, spleen, stomach warp. It has the effects of dispelling summer heat, relieving the exterior, dispelling dampness and harmonizing the stomach. It can treat summer cold, cold and heat headache, chest pain, vomiting and diarrhea, pregnancy vomiting, nasal sinusitis, hand and athlete's foot, etc. ("Dictionary of Chinese Medicine" edited by Nanjing University of Traditional Chinese Medicine Shanghai Science and Technology Press second edition page 3828).
山楂药性酸、甘,微温。归脾、胃、肝经。具有消食健胃,行气散瘀的功效。可治疗饮食积滞,脘腹胀痛,泻泄痢疾、经闭,产后腹痛,恶露不尽,疝气或睾丸肿痛,高血脂症等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第226页)。Hawthorn is sour, sweet and slightly warm. Return spleen, stomach, liver channel. It has the effects of promoting digestion, invigorating the stomach, promoting qi and dispelling blood stasis. It can treat food stagnation, abdominal pain, diarrhea, dysentery, amenorrhea, postpartum abdominal pain, lochia, hernia or testicular swelling, hyperlipidemia, etc. ("Dictionary of Chinese Medicine" edited by Nanjing University of Traditional Chinese Medicine Shanghai Science and Technology Press second edition page 226).
炙甘草药性甘,平。归脾、胃、心、肺经。具有和中缓急,润肺,解毒,调和诸药的功效。可治疗脾胃虚弱,倦怠食少,腹痛便溏,四肢挛急疼痛,心悸,脏躁,肺痿咳嗽;生用治咽喉肿痛,痈疮肿毒,小儿胎毒,及药物、食物中毒等。(《中药大辞典》南京中医药大学编著上海科学技术出版社第二版第792页)。Roasted licorice is sweet in nature and flat. Return spleen, stomach, heart, lung channel. It has the effects of neutralizing urgency, nourishing the lungs, detoxifying, and harmonizing various medicines. It can treat weakness of the spleen and stomach, fatigue and lack of food, abdominal pain and loose stools, acute pain in the limbs, palpitations, visceral irritability, lung flaccidity and cough; it can be used raw to treat sore throat, carbuncle sores, fetal poisoning in children, and drug and food poisoning. ("Dictionary of Chinese Medicine" edited by Nanjing University of Traditional Chinese Medicine Shanghai Science and Technology Press second edition page 792).
本发明遵循中医辩证治疗的原则。诸药相和共具清热化湿,行气消滞的功效,降低血脂,具有疗效确切,无毒副作用,服用方便,价格低廉的特点。The present invention follows the principle of dialectical treatment of traditional Chinese medicine. The combination of various medicines has the effects of clearing away heat and removing dampness, promoting qi and eliminating stagnation, lowering blood lipids, has the characteristics of definite curative effect, no toxic and side effects, convenient administration and low price.
本发明药物临床使用结果表明,有如下优点:Clinical use result of medicine of the present invention shows, has following advantage:
1、本发明选用的中草药各组份符合《卫生部关于进一步规范保健食品原料管理的通知》的规定,利用各味中药的综合作用降低血脂,对人体无毒无害。经动物急性毒性实验表明被实验的动物未见任何毒性反应,其主要脏器也无明显的改变,药物安全可靠。1, each component of the Chinese herbal medicine that the present invention selects meets the regulation of " Ministry of Public Health about further standardizing the notice of raw material management of health food ", utilizes the comprehensive action of various flavors of Chinese medicines to reduce blood fat, and is nontoxic and harmless to human body. The animal acute toxicity test shows that the tested animals have no toxic reaction, and the main organs have no obvious changes, and the drug is safe and reliable.
2、本发明中富含葡萄糖,挥发油,有机酸,维生素,氨基酸,等多种微量元素,利于人体吸收,增强体质。2. The present invention is rich in various trace elements such as glucose, volatile oil, organic acid, vitamins, amino acids, etc., which is beneficial for human body to absorb and enhance physical fitness.
3、本发明具有制作简便、服用方便,价格低廉的特点。3. The present invention has the characteristics of simple manufacture, convenient administration and low price.
具体实施方式 Detailed ways
实施例 胶囊剂 按下述重量称取原料:Example Capsules Weigh the raw materials by the following weights:
茵陈5份 泽泻5份 熟大黄3份5 parts capillary, 5 parts Alisma, 3 parts cooked rhubarb
栀子3份 荷叶3份 首乌藤3份3 parts of gardenia, 3 parts of lotus leaf, 3 parts of Shouwu vine
藿香3份 山楂1份 炙甘草1份Huoxiang 3 parts Hawthorn 1 part Zhilicorice 1 part
制备方法是取上述原料洗净,去杂,加水煎煮两次,第一次1.5~2小时,第二次0.5~1小时,合并两次煎液,滤过,滤液浓缩至80度~85度时,相对密度1.08~1.10的清膏,加入乙醇使清膏含醇量达70%,静置24小时,回收乙醇,在50度~55度时浓缩至相对密度1.30~1.32的清膏,干燥,粉碎成细粉,装入胶囊。每粒装0.3克,通常饭前半小时口服,温开水送下,一次2~10粒,一日三至四次,一个月为一个疗程。患者可以长期服用,且无任何毒副作用。The preparation method is to take the above raw materials, wash them, remove impurities, add water to decoct twice, the first time is 1.5 to 2 hours, and the second time is 0.5 to 1 hour, combine the two decoctions, filter, and concentrate the filtrate to 80 degrees to 85 degrees. When the relative density is 1.08~1.10, add ethanol to make the clear cream contain 70% alcohol, let it stand for 24 hours, recycle ethanol, concentrate to the clear cream with a relative density of 1.30~1.32 at 50~55℃, Dried, crushed into fine powder, packed into capsules. Each capsule contains 0.3 grams, usually taken orally half an hour before meals, given with warm boiled water, 2 to 10 capsules at a time, three to four times a day, one month as a course of treatment. Patients can take it for a long time without any toxic and side effects.
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中医治疗脂肪肝的方药研究. 杨智军.药学进展,第22卷第3期. 1998 * |
中医药治疗脂肪肝的分析探讨. 孔祥廉等.时珍国医国药,第14卷第12期. 2003 * |
国家中成药标准汇编 中成药地方标准上升国家标准部分 内科心系分册. 国家药品监督管理局,143-144. 2002 * |
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