CN100473424C - Blood transfusion system - Google Patents

Abstract

The present invention provides a blood transfusion system having valve circuit, for transfusion of blood to a patient, said system comprising a Y-shaped connector comprising of three arms and ajunction, wherein arm 7 is connected to the patient at tisone end and to the junction at its other end, arm is connected to the junction at its one end and to a waste-blood suction syringe at its other end through a valve, an outlet is being provided in the arm between the valve 11 and the waste-blood suction syringe for dispensing the waste blood, arm is connected to the junction at its one end and to a fresh-blood supplying syringe at its other end through a valve, a fresh-blood supplying means is being connected in the arm 16(b) between the valve 14 and the fresh-blood supplying syring through valve, and syringes and are being operated synchronously.

Description

blood transfusion system

technical field

The present invention provides a blood transfusion system having a valve circuit for transfusing blood to a patient.

Background technique

A transfusion is the exchange of fresh blood for infected blood in newborns who are jaundiced, have certain blood-related disorders, and are used for those babies whose mothers have an O (Rh-negative) blood type. Blood transfusions require successive repeated cycles of aspiration of approximately 5-20 ml of infected blood while simultaneously transfusing the same volume of fresh blood. Blood transfusions are given through disposable valves and several syringe sets. Instruments based on this method, known as blood transfusion controllers, have certain advantages, such as accuracy and precision of blood transfusion at a predetermined rate, and various alarms to attract the attention of the operator if the instrument is not working properly .

Reference can be made to the current neonatal blood transfusion system, which requires an experienced nurse or doctor to sit at the bedside continuously for 5-6 hours while keeping a record of the number of blood draws and transfusions. The requirements of the prior art are illustrated in Figure 1 of the accompanying drawings of this specification. The entire process requires 4 syringe strokes. The circuit employs two three-way pistons 1 and 2 with a syringe 3 and two intravenous (I.V.) sets 4 and 5. During the outward stroke of the syringe 3 during the first stroke, the infected blood is withdrawn with the syringe 3 through a dedicated tubing 6 fitted to the patient's umbilical vein. The piston 1 is manually rotated in such a way that during the inward stroke of the syringe 3 infected blood passes through the IV set 4 to the waste bottle. Now, the piston 2 is manually rotated in this way, so that the fresh blood is aspirated from the bottle by the outward stroke of the syringe 3 . Both pistons 1 and 2 are then manually rotated so that an inward stroke of one syringe 3 infuses blood into the baby through the same conduit. This process requires 5 rotations of the three-way plunger and 4 syringe strokes for each transfusion and blood draw cycle, which requires the physician to remain vigilant throughout the process. In addition, the required proper rate of blood transfusion cannot be maintained due to human factors involved, thus increasing the chance of blood cell rupture. It is a cumbersome procedure and requires keeping a proper record of transfusion and blood draw cycles and blood volumes. In addition, when the suction and output speed of blood is changed due to manual operation, there are more chances of blood cell rupture. Therefore, there is a need to improve the current blood transfusion system.

Contents of the invention

The main object of the present invention is to provide a blood transfusion system with a valve circuit, which overcomes the above-mentioned disadvantages.

Another object of the present invention is to provide an automatic blood transfusion system in which fewer syringe strokes are required.

Yet another object of the present invention is to provide an automatic blood transfusion system which will result in minimal physician involvement and which is only used to check the function of the instrument at any time, thereby overcoming the above-mentioned disadvantages.

Still another object of the present invention is to provide an automatic blood transfusion system which can transfuse blood at a desired fixed rate, thereby eliminating the chance of blood cell rupture, thereby overcoming the above disadvantages.

Yet another object of the present invention is to provide an automatic blood transfusion system which can have ready recording, alarm and display of blood exchanged.

According to the present invention, a blood transfusion system having a disposable valve circuit for delivering blood to a patient, said system comprising a Y-connector comprising arms connected to the patient, The arm of the waste blood aspiration syringe, the arm of the blood supply syringe and a junction, wherein the arm connected to the patient is connected at its one end to the patient and at its other end to the junction, the waste blood aspiration syringe The arm is connected at its one end to the joint and at its other end to a variable volume waste blood aspiration syringe through a one-way disposable waste blood syringe valve, an outlet being provided at the waste blood draw In the arm of the aspiration syringe, between the disposable waste blood syringe valve and the waste blood aspiration syringe for dispensing waste blood, the arm of the fresh blood supply syringe is connected at its one end to the joint and at its other end Connected to a variable volume blood supply syringe through a one-way disposable blood syringe valve, a blood supply device is connected through a disposable blood valve in the arm of the blood supply syringe between the disposable blood syringe valve and the blood supply syringe between, and the waste blood aspiration syringe, the fresh blood supply syringe are connected to the slider, and they are operated synchronously by hand or by a drive mechanism, wherein the waste blood syringe valve and the fresh blood valve are synchronously operated so as to draw and draw from the patient simultaneously Transfuse the same amount of blood into the patient's body.

In accordance with the present invention, a blood transfusion system having a disposable valve circuit for delivering blood to a patient, said system comprising a Y-connector comprising an arm waste connected to the patient The arms of the blood aspiration syringe, the arms of the fresh blood supply syringe and a junction, wherein the arm connected to the patient is connected at its one end to the patient and at its other end to the junction, and the arm of the waste blood aspiration syringe The arm is connected at its one end to the joint and at its other end to a waste blood aspiration syringe through a one-way disposable waste blood syringe valve, an outlet being provided in the arm of the waste blood aspiration syringe , between the disposable waste blood syringe valve and the waste blood aspiration syringe used for dispensing waste blood, the arm of the blood supply syringe is connected at its one end to the joint and passed through a one-way primary at its other end The blood syringe valve is connected to a blood supply syringe, a blood supply device is connected in the arm of the blood supply syringe through a disposable blood valve between the disposable blood syringe valve and the blood supply syringe, and the waste blood aspiration syringe, The blood supply syringes are attached to the sliders and they are manually synchronized or operated synchronously by a drive mechanism, wherein the waste blood syringe valve and the fresh blood valve are synchronously operated so as to simultaneously draw from and infuse substantially the same amount of blood into the patient .

Description of drawings

In the accompanying drawings of this manual

Figure 1 represents the system of various elements used in the prior art and their operation.

Figure 2 represents the blood transfusion system of the present invention and its operation.

Detailed ways

Accordingly, the present invention provides a blood transfusion system having a valve circuit for delivering blood to a patient, said system comprising a Y-connector comprising 3 arms (with the patient connected arm 7, the arm 16a of the waste blood aspiration syringe, the arm 16b of the fresh blood supply syringe) and a junction 9, wherein the arm 7 connected to the patient is connected to the patient at its one end, and at its other end Connected to the junction 9, the arm 16a is connected to the junction 9 at its one end, and is connected to a waste blood suction syringe 10 through a waste blood syringe valve 11 at its other end, an outlet is provided at the arm 16a Between the waste blood injector valve 11 and the waste blood aspiration syringe, for distributing waste blood, the arm 16b is connected at one end to the junction 9, and at its other end to a blood injector valve 14 to a On the fresh blood supply syringe 13, a fresh blood supply device is connected between the fresh blood syringe valve 14 and the fresh blood supply syringe in the arm 16b through a fresh blood valve 15, and the waste blood aspiration syringe 10 and the fresh blood supply syringe 13 operate synchronously.

In one embodiment of the invention, the patient-attached arm 7 is attached to the umbilical vein of an infant patient.

In another embodiment of the present invention, the waste blood syringe valve 11, the fresh blood syringe valve 14 and the fresh blood valve 15 are disposable valves.

In yet another embodiment of the present invention, the waste blood injector valve 11 , the fresh blood injector valve 14 and the fresh blood valve 15 are one-way valves.

In yet another embodiment of the present invention, the waste blood aspirated from the patient is collected in a waste blood collection device connected to an outlet provided on the arm 16a.

In another embodiment of the present invention, the waste blood collection device is connected to the outlet through a one-way disposable blood waste valve 12 .

In yet another embodiment of the present invention, the one-way disposable waste blood valve 12 is connected to the waste blood collection device through the intravenous injection device 4 .

In another embodiment of the present invention, the fresh blood valve 15 is connected to the fresh blood supply device through the intravenous injection set 5 .

In one embodiment of the present invention, the waste blood syringe valve 11, the waste blood valve 12, the fresh blood syringe valve 14 and the fresh blood valve 15 can be controlled manually or by a stepping motor.

In another embodiment of the invention, waste blood from the patient and fresh blood from the fresh blood supply are aspirated simultaneously.

In yet another embodiment of the present invention, fresh blood is pumped to the patient and waste blood is pumped to the waste blood collection device simultaneously.

In yet another embodiment of the present invention, when the waste blood is aspirated from the patient, the waste blood syringe valve 11 is opened and the waste blood valve 12 is closed, and when the waste blood is pumped to the waste blood collection device, the waste blood Blood valve 12 is open and waste blood syringe valve 11 is closed.

In another embodiment of the present invention, wherein the blood valve 15 is opened and the blood syringe valve 14 is closed when the blood is drawn from the blood supply, and the blood syringe valve 14 is opened and closed when the blood is pumped into the patient. The fresh blood valve 15 is closed.

In yet another embodiment of the present invention, the blood waste valve 12 and the fresh blood syringe valve 14 operate synchronously.

In another embodiment of the present invention, the waste blood injector valve 11 and the fresh blood valve 15 operate synchronously.

In one embodiment of the invention, each syringe can be operated manually or with a syringe drive mechanism.

In another embodiment of the present invention, the above-mentioned syringe drive mechanism comprises a slider 8 connected to a motor 17 through a device 18 for converting the rotary motion of the motor into linear motion.

In yet another embodiment of the present invention, the waste blood aspiration syringe 10 and the fresh blood supply syringe 13 may have the same volume or variable volumes.

In yet another embodiment of the invention, the syringes are replaceable to vary the volume of blood exchanged during a stroke.

In another embodiment of the invention, the valves used may be disposable and may be made of polycarbonate and silicone rubber compatible with medical fluids.

In yet another embodiment of the present invention, transfused blood may be withdrawn from the umbilical vein through the umbilicus.

In a further embodiment of the present invention, the syringe used may have a volume between 5-20ml.

In one embodiment of the invention, the power source used to drive the motor may be, for example, mains power, accumulators, rechargeable batteries.

An embodiment of the device of the present invention is shown in Figure 2 of the accompanying drawings of this specification.

The device of the present invention is shown in Figure 2 of the accompanying drawings of this specification. The schematic can be divided into three main parts. They are:

(i) Disposable valve circuit

(ii) Syringe Fixture

(iii) Syringe drive unit

1. Disposable valve circuit: The circuit consists of 4 one-way valves, an umbilicus, 3 Y-connectors, 2 syringes and suitable tubing for interconnection. The one-way valve is a single-use type and is made for use with liquid medicine. These materials of manufacture are silicone rubber and polycarbonate. No static electricity is generated, and these are pressure cooker sterilizable. All tubing consists of standard commercially available I.V. device tubing and forms tight joints. It is a low cost system and can be easily produced.

2. Syringe fixing device: Syringes with a capacity between 5-25ml need to be fixed. The clamping device only requires loosening and tightening of the screw after placing the syringe into a V-groove.

3. Syringe driving device: it consists of a motor, a slider and a driving mechanism. The syringes are clamped with their plunger ends in movable sliders secured to a rack. The drive mechanism includes a rack and pinion arrangement.

The device of the present invention operates as follows:

Any commercially available adult or pediatric I.V. device can be used. Tubing for connection to the umbilical vein is also available. Insert the syringes together with their plunger ends in the slider 8 into the rack. All disposable valves, pipelines are connected with each syringe according to the circuits in the figure (2) of the accompanying drawings of this description. Place the blood container at the open end of the umbilicus and at the open end of the I.V. Turn on the main switch. The motor will start, and each syringe moves toward top dead center. The one-way waste blood syringe valve 11 and the fresh blood valve 15 start to open, and the whole system starts to fill with fresh blood. During the return stroke, the blood waste valve 12 and the blood syringe valve 14 begin to open. This way all the air bubbles start to be eliminated. The device is then disabled when both syringes are at their bottom dead center. Connect the patient's umbilical vein to tubing 7. Turn the switch on to the main circuit. The transfusion cycle begins.

The main specifications of an embodiment of the device of the present invention can be characterized as follows:

Specification

Volume exchanged in one stroke: 5-20ml

Flow rate: variable

Main power supply: 220VAC (AC), 50Hz.

System - Fluid is delivered through readily available tubing and syringes and check valves are driven by a stepper motor.

The following examples are given as illustrations only, and therefore should not be seen as limiting the scope of the invention.

example 1

Flow rate = 20ml/min. Precisely 200ml of green liquid is bottled (say a patient), and exactly 200ml of red liquid is bottled (blood). The motor speed was set at 20ml/min. The liquid is consumed in exactly 10 minutes.

The main advantages of the present invention are:

1. Adopt disposable valve circuit.

2. All valves and pipelines can be sterilized with a pressure cooker, and can be used together with liquid medicine.

3. Cycle with fewer syringe strokes.

4. It provides the basis for developing an automatic blood transfusion device that will have minimal physician involvement and that is only for frequent testing of the instrument's functionality.

5. It provides the basis for the development of automatic blood transfusion devices that can transfuse blood at a desired fixed rate, thus eliminating the chance of blood cell fragmentation.

6. It provides the basis for the development of an automatic blood transfusion device according to the method studied which records, alarms and displays the volume of blood exchanged.

7. According to the studied system, an automatic blood transfusion device can be designed and manufactured. It may have some radio and visual alarms to make the system safe and malfunction-proof, so far as possible. Various features that can be included are: LCD (Liquid Crystal Display) display of blood transfusion and draw volume and total time spent during transfusion, selection of flow rate via switch, LCD display for flow rate and alarms for: Air bubbles, high flow rates, completion of operations, leaks in the circuit, high pressure required for blood transfusion. Rechargeable batteries and their indicators should be provided. If any of the above alarm conditions are observed, the system should stop immediately.

Claims (22)

1. blood transfusion system, described blood transfusion system has disposable valve loop, be used for blood transport in patient's body, said system comprises a Y-connection, described Y-connection comprises the arm (7) that links to each other with the patient, the arm (16a) of useless blood suction syringe, blood is supplied with the arm (16b) and a joint (9) of syringe, wherein the arm that links to each other with the patient (7) is connected to the patient and is connected on the joint (9) at its other end place at its an end place, the arm (16a) of useless blood suction syringe is connected to joint (9), and upward and at its other end place unidirectional disposable useless blood syringe valve (11) is connected on the useless blood suction syringe of a variable-displacement (10) by one at its an end place, an outlet is arranged in the arm (16a) of useless blood suction syringe, at disposable useless blood syringe valve (11) be used to distribute between the useless blood suction syringe of useless blood, the arm (16b) of blood supply syringe is connected to joint (9), and upward and at its other end place unidirectional disposable blood syringe valve (14) is connected on the variable-displacement blood supply syringe (13) by one at its an end place, blood feedway is connected blood by a disposable blood valve (15) and supplies with in the arm (16b) of syringe and supply with between the syringe at disposable blood syringe valve (14) and blood, and useless blood suction syringe (10), blood is supplied with syringe (13) and is connected on the slider, with manual synchronization operation they or with driving mechanism simultaneously operating they, wherein useless blood syringe valve (11) and blood valve (15) simultaneously operating are so that aspirate and the commensurability substantially blood of input in the patient body in the patient body simultaneously.

2. blood transfusion system as claimed in claim 1, wherein the arm that links to each other with the patient (7) is connected on the umbilical vein of infant patients.

3. blood transfusion system as claimed in claim 2, wherein transfusing blood obtains from umbilical vein by umbilical canal.

4. blood transfusion system as claimed in claim 1, wherein the useless blood that will extract out in patient's body is collected in the useless blood gathering-device, and described useless blood gathering-device is connected in the outlet on the arm (16a) that is arranged on useless blood suction syringe.

5. blood transfusion system as claimed in claim 4, wherein useless blood gathering-device is connected in the outlet by a unidirectional disposable useless blood valve (12).

6. blood transfusion system as claimed in claim 5, wherein unidirectional disposable useless blood valve (12) is connected on the useless blood gathering-device by intravenous injection device (4).

7. blood transfusion system as claimed in claim 1, wherein blood valve (15) is connected on the blood feedway by intravenous injection device (5).

8. blood transfusion system as claimed in claim 5, the operation of wherein useless blood syringe valve (11), useless blood valve (12), blood syringe valve (14) and blood valve (15) is with manually controlling or with a step motor control.

9. blood transfusion system as claimed in claim 8, wherein used valve Merlon compatible and silicone rubber manufacturing with medicinal liquid.

10. blood transfusion system as claimed in claim 1, the wherein useless blood of suction and carry out simultaneously in patient's body from blood feedway suction blood.

11. blood transfusion system as claimed in claim 1 wherein is pumped into blood in patient's body and the blood pump that will give up is delivered to useless blood gathering-device and carried out simultaneously.

12. blood transfusion system as claimed in claim 1, wherein when in patient's body, aspirating out useless blood, useless blood syringe valve (11) opens and useless blood valve (12) cuts out, and when the blood pump that will give up was delivered to useless blood gathering-device, giving up, blood valve (12) was opened and useless blood syringe valve (11) cuts out.

13. blood transfusion system as claimed in claim 1, when when the blood feedway aspirates out blood, blood valve (15) opens with blood syringe valve (14) and cuts out, and when blood being pumped in patient's body, blood syringe valve (14) opens with blood valve (15) and cuts out.

14. blood transfusion system as claimed in claim 8, wherein useless blood valve (12) and blood syringe valve (14) simultaneously operating.

15. blood transfusion system as claimed in claim 1, wherein slider (8) is connected in the injector drive mechanism.

16. blood transfusion system as claimed in claim 15, wherein the said syringe driving mechanism comprises a motor by power drives (17), and above-mentioned motor is connected to one and is used for rotatablely moving of motor is transformed into straight-line device (18).

17. blood transfusion system as claimed in claim 15, wherein slider (8) is connected to and is used for rotatablely moving of motor is transformed into straight-line device (18).

18. blood transfusion system as claimed in claim 16, the power supply that wherein is used for drive motors are feeder cable power supply or accumulator or rechargeable battery.

19. blood transfusion system as claimed in claim 1, wherein used syringe has capacity between 5-20ml.

20. blood transfusion system as claimed in claim 1, wherein each syringe can be changed, so that change the blood volume that is exchanged in a stroke.

21. blood transfusion system, described blood transfusion system has disposable valve loop, be used for blood transport in patient's body, said system comprises a Y-connection, described Y-connection comprises the arm (7) that links to each other with the patient, the arm (16a) of useless blood suction syringe, blood is supplied with the arm (16b) and a joint (9) of syringe, wherein the arm that links to each other with the patient (7) is connected to the patient and is connected on the joint (9) at its other end place at its an end place, the arm (16a) of useless blood suction syringe is connected to joint (9), and upward and at its other end place unidirectional disposable useless blood syringe valve (11) is connected on the useless blood suction syringe (10) by one at its an end place, an outlet is arranged in the arm (16a) of useless blood suction syringe, at disposable useless blood syringe valve (11) be used to distribute between the useless blood suction syringe of useless blood, the arm (16b) of blood supply syringe is connected to joint (9), and upward and at its other end place unidirectional disposable blood syringe valve (14) is connected on the blood supply syringe (13) by one at its an end place, blood feedway is connected blood by a disposable blood valve (15) and supplies with in the arm (16b) of syringe and supply with between the syringe at disposable blood syringe valve (14) and blood, and useless blood suction syringe (10), blood is supplied with syringe (13) and is connected on the slider, with manual synchronization operation they or with driving mechanism simultaneously operating they, wherein useless blood syringe valve (11) and blood valve (15) simultaneously operating are so that aspirate and the commensurability substantially blood of input in the patient body in the patient body simultaneously.

22. blood transfusion system as claimed in claim 21, wherein used syringe has capacity between 5-20ml.

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