CN100457170C - A Medicine for treatment of gastrointestinal diseases - Google Patents
A Medicine for treatment of gastrointestinal diseases Download PDFInfo
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- CN100457170C CN100457170C CNB2006101340025A CN200610134002A CN100457170C CN 100457170 C CN100457170 C CN 100457170C CN B2006101340025 A CNB2006101340025 A CN B2006101340025A CN 200610134002 A CN200610134002 A CN 200610134002A CN 100457170 C CN100457170 C CN 100457170C
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- 239000003814 drug Substances 0.000 title claims abstract description 23
- 208000018522 Gastrointestinal disease Diseases 0.000 title claims abstract description 9
- 229940079593 drug Drugs 0.000 title description 9
- 241000218176 Corydalis Species 0.000 claims abstract description 8
- 239000009636 Huang Qi Substances 0.000 claims abstract description 4
- 208000010643 digestive system disease Diseases 0.000 claims description 8
- 208000018685 gastrointestinal system disease Diseases 0.000 claims description 8
- 241000756943 Codonopsis Species 0.000 claims description 7
- 239000010271 massa medicata fermentata Substances 0.000 claims description 7
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 5
- 239000002994 raw material Substances 0.000 claims 1
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- 230000001737 promoting effect Effects 0.000 description 9
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- 241000545442 Radix Species 0.000 description 4
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- 208000002193 Pain Diseases 0.000 description 3
- 208000007107 Stomach Ulcer Diseases 0.000 description 3
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 230000029087 digestion Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
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- 208000000718 duodenal ulcer Diseases 0.000 description 3
- 230000008673 vomiting Effects 0.000 description 3
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
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- 206010046274 Upper gastrointestinal haemorrhage Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000008034 disappearance Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 210000004211 gastric acid Anatomy 0.000 description 2
- 201000005917 gastric ulcer Diseases 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
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- 210000004072 lung Anatomy 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 206010006784 Burning sensation Diseases 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- 206010018498 Goitre Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
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- 206010067171 Regurgitation Diseases 0.000 description 1
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- KZFDVWZZYOPBQZ-UHFFFAOYSA-K bismuth;potassium;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [K+].[Bi+3].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KZFDVWZZYOPBQZ-UHFFFAOYSA-K 0.000 description 1
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- 239000003172 expectorant agent Substances 0.000 description 1
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- 230000002401 inhibitory effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
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- 229940055726 pantothenic acid Drugs 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 230000001175 peptic effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
A medicine used in the treatment of gastrointestinal diseases, comprising the following ingredients by weight: rhizoma bletillae 10-30 doses, halloysitum rubrum10-30 doses, concha arcae 10-30 doses, wuzeigu 10-30 doses, fructus amomi 10-30 doses, radix codonopsis10-30 doses, rhizoma corydalis 10-30 doses, rhizoma atractylodis macrocephalae 10-30 doses. rhizoma coptidis 10-30 doses, massa fermentata10-30 doses, rhizoma atractylodis10-30 doses, radix astragali 10-30 doses. The invention has the advantages of effective, high cure rate, no relapse and so on.
Description
Technical field
The present invention is a kind of medicine and method for making thereof for the treatment of gastrointestinal disease.
Background technology
At present, gastrointestinal disease is human commonly encountered diseases, frequently-occurring disease, is worldwide distribution, estimates to have approximately 10% population to suffer from this disease in life.Mainly comprise symptoms such as acute or chronic gastritis, functional dyspepsia, main performance has epigastrium flatulence discomfort, burning sensation or pain, anorexia or early full, feel sick, vomiting, belch, acid regurgitation and noisy sense and digestive tract hemorrhage etc.Therapeutic Principle, method are varied, at present, on the market medicine of treatment gastrointestinal disease have that WEIDE is peaceful, bismuth potassium citrate, gavirin tablet, gastrointestinal peace sheet etc., these medicines be mostly simple anti-inflammation or simple by gastric acid inhibitory, in and gastric acid control some symptoms of gastroenteropathy, in case drug withdrawal, relapse rate is high.
Summary of the invention
Therefore, still there is demand in people for the medicine of the treatment gastrointestinal disease of better efficacy.Up to now, also do not find the report of any relevant pharmaceutical composition of the present invention.The inventor according to a large amount of clinical practices, proves and adopts Drug therapy of the present invention that through research for many years the cure rate height does not recur after healing.
The medicine of the treatment gastrointestinal disease that the purpose of this invention is to provide a kind of cure rate height of better efficacy, do not recur after more.
The consumption of drug component of the present invention is repeatedly studied with the clinical trial summary through the inventor and is drawn, and each amounts of components is for all to have better curative effect in the following weight parts scope:
Pseudobulbus Bletillae (Rhizoma Bletillae) 10-30 part, Halloysitum Rubrum 10-30 part, Concha Arcae 10-30 part, Os Sepiae 10-30 part, Fructus Amomi 10-30 part, Radix Codonopsis 10-30 part, Rhizoma Corydalis 10-30 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Rhizoma Coptidis 10-30 part, Massa Medicata Fermentata 10-30 part, Rhizoma Atractylodis 10-30 part, Radix Astragali 10-30 part.
Be preferably: 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Halloysitum Rubrums, 15 parts of Concha Arcaes, 20 parts of Os Sepiae, 20 parts of Fructus Amomis, 15 parts of Radix Codonopsis, 15 parts of Rhizoma Corydalis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Rhizoma Coptidis, 15 parts of Massa Medicata Fermentata, 15 parts of Rhizoma Atractylodis, 15 parts of the Radixs Astragali.Said medicine all can directly have been bought in pharmacy.
Medicine of the present invention adopts conventional pharmaceutical methods to make powder or other any pharmacy dosage form for oral administration.
The pharmacological action of each constituent medicine of the present invention is as follows:
The Pseudobulbus Bletillae (Rhizoma Bletillae): tonifying the lung hemostasis, nourishing the stomach granulation promoting.Be applicable to that lung gastrorrhagia, gastric and duodenal ulcers are hemorrhage etc.
Halloysitum Rubrum: Halloysitum Rubrum is a Kaolin, red smooth matter exquisiteness, the sticking tongue earth gas of licking, astringing intestine to stop diarrhea hemostasis and granulation promoting.
Concha Arcae: expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.Be used for the long-pending knot of pertinacious phlegm, the thickness difficulty is coughed up, goiter, scrofula, abdominal mass mass in the abdomen, stomachache pantothenic acid.
Os Sepiae: Os Sepiae has nourishing the stomach benefit essence, astringing to arrest bleeding, relieving gastric hyperacidity to alleviate stomachache, expelling pus and promoting granulation effect.
Fructus Amomi: promoting the circulation of QI to relieve pain, spleen invigorating relieving distension, antiabortive preventing or arresting vomiting.Through test fragrant digestion promoting function is arranged, can promote the secretion of peptic digestion liquid, and get rid of the digestive tract pneumatosis.Clinical stagnation of QI in spleen and stomach, the stomachache distension of being used for; Deficiency and coldness of spleen and stomach, feeling of stuffiness in chest vomiting.
Radix Codonopsis: can invigorating the spleen and replenishing QI, to control deficiently, the lack of appetite body is tired, and chronic diarrhea is quenched one's thirst.
Rhizoma Corydalis: effect with blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain.
The Rhizoma Atractylodis Macrocephalae: sweet in the mouth, warm in nature, go into the taste warp, good air making-up and spleen enlivening effect is arranged.
Rhizoma Coptidis: the effect of eliminating fire and detoxication.
Massa Medicata Fermentata: can strengthen the effect of its promoting digestion and removing stagnation, invigorating the spleen and regulating the stomach behind the parching to brown.
Rhizoma Atractylodis: have spleen invigorating, dampness, resolving depression, ward off dirty, the effect of expelling cold and relieving exterior syndrome.
The Radix Astragali: have invigorating QI to consolidate the body surface resistance, the effect of holder skin ulcer granulation promoting, diuretic.
Cure mainly; Gastric ulcer, duodenal ulcer, upper gastrointestinal hemorrhage, various gastritis.
Function: the cold expelling that is good for the stomach, putrefaction removing and tissue regeneration promoting.
Advantages such as that the present invention has is evident in efficacy, cure rate is high, do not recur after more.
The specific embodiment
[clinical efficacy test report]
1, physical data
Accept out-patient's totally 100 examples for medical treatment, wherein male 70 examples, women 30 examples, age 15-30 year 38 examples, 31-40 year 22 examples, 41-50 year 23 examples, 17 examples more than 50 years old.
2, Therapeutic Method
Medicine of the present invention is summed up through clinical trial for many years, and for symptoms such as gastric ulcer, duodenal ulcer, upper gastrointestinal hemorrhage, various gastritis, 15 days is a course of treatment, usage and dosage is: oral, three times on the one, each 10 grams are taken a course of treatment or two courses of treatment.
3, efficacy assessment standard
Produce effects: all clinical symptom disappearance, drug withdrawal are followed up a case by regular visits to and are not seen recurrence more than half a year;
Take a turn for the better: all clinical symptom disappearance, drug withdrawal are followed up a case by regular visits to a light symptoms half a year by chance;
Invalid: it is invalid not meeting effective standard.
4, therapeutic outcome (see Table 1)
Table 1 is observation of curative effect after treating
In a word, in two months clinical practice, with medicine of the present invention treatment patient 100 examples, produce effects 99 examples as a result, 1 example that takes a turn for the better, invalid 0 example, obvious effective rate is 99%, and improvement rate is 1%, and total effective rate is 99%.
Come further to illustrate medicine of the present invention and preparation method thereof by the following examples.
Embodiment 1
The consumption of drug component of the present invention is repeatedly studied with the clinical trial summary through the inventor and is drawn, and each amounts of components is preferably: 20 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 15 parts of Halloysitum Rubrums, 15 parts of Concha Arcaes, 20 parts of Os Sepiae, 20 parts of Fructus Amomis, 15 parts of Radix Codonopsis, 15 parts of Rhizoma Corydalis, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts of Rhizoma Coptidis, 15 parts of Massa Medicata Fermentata, 15 parts of Rhizoma Atractylodis, 15 parts of the Radixs Astragali.
Said medicine all can directly have been bought in pharmacy.
Medicine of the present invention adopts conventional pharmaceutical methods to make powder or other any pharmacy dosage form for oral administration.
Embodiment 2
10 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 10 parts of Halloysitum Rubrums, 10 parts of Concha Arcaes, 10 parts of Os Sepiae, 10 parts of Fructus Amomis, 30 parts of Radix Codonopsis, 30 parts of Rhizoma Corydalis, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Rhizoma Coptidis, 30 parts of Massa Medicata Fermentata, 30 parts of Rhizoma Atractylodis, 30 parts of the Radixs Astragali.
Medicine of the present invention adopts conventional pharmaceutical methods to make powder or other any pharmacy dosage form for oral administration.
Embodiment 3
30 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 30 parts of Halloysitum Rubrums, 30 parts of Concha Arcaes, 30 parts of Os Sepiae, 30 parts of Fructus Amomis, 10 parts of Radix Codonopsis, 10 parts of Rhizoma Corydalis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Rhizoma Coptidis, 10 parts of Massa Medicata Fermentata, 10 parts of Rhizoma Atractylodis, 10 parts of the Radixs Astragali.
Medicine of the present invention adopts conventional pharmaceutical methods to make powder or other any pharmacy dosage form for oral administration.
Claims (1)
1, a kind of medicine for the treatment of gastrointestinal disease is characterized in that this medicine is to be made by the following raw material medicaments in part by weight proportioning:
Pseudobulbus Bletillae (Rhizoma Bletillae) 10-30 part, Halloysitum Rubrum 10-30 part, Concha Arcae 10-30 part, Os Sepiae 10-30 part, Fructus Amomi 10-30 part, Radix Codonopsis 10-30 part, Rhizoma Corydalis 10-30 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Rhizoma Coptidis 10-30 part, Massa Medicata Fermentata 10-30 part, Rhizoma Atractylodis 10-30 part, Radix Astragali 10-30 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101340025A CN100457170C (en) | 2006-10-24 | 2006-10-24 | A Medicine for treatment of gastrointestinal diseases |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101340025A CN100457170C (en) | 2006-10-24 | 2006-10-24 | A Medicine for treatment of gastrointestinal diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1943754A CN1943754A (en) | 2007-04-11 |
| CN100457170C true CN100457170C (en) | 2009-02-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006101340025A Expired - Fee Related CN100457170C (en) | 2006-10-24 | 2006-10-24 | A Medicine for treatment of gastrointestinal diseases |
Country Status (1)
| Country | Link |
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| CN (1) | CN100457170C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926955B (en) * | 2010-08-26 | 2012-06-27 | 河南大学消化病研究所 | Medicament for treating stomach illness |
| CN102755635B (en) * | 2012-07-27 | 2014-05-28 | 广州加原医药科技有限公司 | Composition for improving gastrointestinal function and preparation method thereof |
| CN104771657A (en) * | 2015-04-26 | 2015-07-15 | 赵霞 | Traditional Chinese medicine composition for treating gastric ulcer |
| CN105168904A (en) * | 2015-08-31 | 2015-12-23 | 李丽芬 | Traditional Chinese medicine preparation for treating chronic gastric ulcer or duodenal ulcer |
| CN106562997A (en) * | 2016-11-23 | 2017-04-19 | 岑立君 | Composition and preparation method of effective spurrite medicine |
| CN109420113A (en) * | 2017-08-31 | 2019-03-05 | 黄文利 | A kind of Chinese medicine composition for treating peptic ulcer disease |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1218685A (en) * | 1998-10-30 | 1999-06-09 | 阎作礼 | Capsule for enterogastric disease |
-
2006
- 2006-10-24 CN CNB2006101340025A patent/CN100457170C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1218685A (en) * | 1998-10-30 | 1999-06-09 | 阎作礼 | Capsule for enterogastric disease |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1943754A (en) | 2007-04-11 |
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Granted publication date: 20090204 Termination date: 20111024 |