CN100450426C - Endoscope apparatus - Google Patents

Abstract

An endoscope apparatus comprises: an endoscope comprising an imaging device that forms a color image signal of a body to be observed; a storage portion that stores matrix data regarding a wavelength range in which a spectral image is constituted; a spectral image forming circuit that conducts matrix calculation based on the color image signals by using the matrix data of the storage portion and forms a spectral image of a selected wavelength range; and a wavelength selecting section that selects the wavelength range of the spectral image formed by the spectral image forming circuit through a continuous changeover or a step-wise changeover.

Description

Endoscope apparatus

Technical field

The present invention relates to endoscope apparatus, the formation of particularly in medical field, using, be used to form the spectroscopy scheme picture (image) that demonstration is made up of the image information of optional frequency range.

Background technology

In recent years, in the electronic endoscope apparatus that uses solid photographic device, according to the spectral reflectance of digestive organs (gastric mucosa etc.), the spectroscopic imaging of combination narrow-band band pass filter, promptly narrow-band filtering built-in electronic endoscope apparatus (Narrow Band Imaging-NBI) gets most of the attention.This device replaces the surface to press the light filter of R (red), G (green), B (orchid) rotation in turn, design the band pass filter of 3 narrow (wavelength) frequency bands, export illumination light in turn by these arrowband band pass filters, for 3 signals that obtain by these illumination light, form the spectroscopy scheme picture by changing its weighting, enforcement and R, identical processing of G, B (RGB) RST separately.According to such spectroscopy scheme picture, in the digestive organs of stomach, large intestine etc., can extract unavailable microstructure etc. in the past.

On the other hand, what adopt above-mentioned arrowband band pass filter is not surface formula in turn, as the analysis/evaluation of the digital color image in the distribution of patent 2003-93336 communique, juridical person Tokyo University publishing house, author three residence oceans one (shown in the P148～P153), disclose in the light filter of the small mosaic texture of configuration in solid photographic device, based on the picture signal that obtains by white light, adopt calculation process to form the spectroscopy scheme picture.This is that the relation of the logical dichroism of the specific arrowband band of each colour sensitivity characteristic of the RGB of numeric dataization and numeric dataization is found the solution as matrix data (coefficient settings value), according to the computing of this matrix data and rgb signal, obtain being similar to the spectroscopy scheme image signal that can obtain by the arrowband band pass filter.By such computing, form spectroscopy scheme as the time, do not need to prepare a plurality of light filters of corresponding desired frequency band, do not need to exchange the configuration of these light filters in addition, so thereby can avoid the maximization of device to seek cost degradation yet.

Yet, in the formation of the spectroscopy scheme picture of above-mentioned endoscope apparatus, consider the blood vessel of the target that will depict thicker blood vessel, blood capillary or deep-seated the are arranged blood vessel of putting, shallow position, sb.'s illness took a turn for the worse different a plurality of kinds or the states such as cancerous tissue of degree, in addition, the relation of the frequency range of selecting the zone of these care and should selecting, individual variation according to observed body, also have different situations, thus to obtain describing the care zone expected optimal spectroscopy scheme picture frequency range selection, to set be not easily.

On the other hand, for example analyzed with depict oxyhemoglobin and deoxy haemachrome etc., frequency range when difference between specific material is target, at such target, expectation can obtain being set in the spectroscopy scheme picture on the frequency range of regulation rapidly.

Summary of the invention

The present invention proposes just in view of the above problems, and its purpose is to provide a kind of endoscope apparatus, and it can select the frequency range that is used to form the spectroscopy scheme picture of depicting desired destination easily and rapidly.

Also have, after forming, showing the spectroscopy scheme picture of easily observing clinically, optimal frequency range is often because the difference of clinicist's etc. device operator and difference, even be considered to the suitableeest frequency range so the position of corresponding observed body is prepared in advance, also exist each clinicist to wait and when the spectroscopy scheme picture forms, can not utilize, must select to be suitable for the situation of operation of the frequency range of self sensitivity one by one.If like that, want to form, show for each device operator self, the spectroscopy scheme picture of easy observation, will need for a long time.

The present invention proposes in view of the above problems, and purpose is to provide a kind of endoscope apparatus, and it is for each device operator self, the spectroscopy scheme picture of easy observation that can form rapidly, show.

In order to achieve the above object, the 1st invention is characterised in that, is loaded into picture pick-up device in the endoscope in utilization, forms in the endoscope apparatus of colour picture signal of observed body and be provided with: storage constitutes the storage part of matrix data (coefficient data) of the frequency range of spectroscopy scheme picture; Utilize the matrix data of this storage part, implement the matrix operations based on above-mentioned colour picture signal, the spectroscopy scheme picture of spectroscopy scheme picture that forms the frequency range of selecteed arbitrary value forms circuit; To look like to form the frequency range of circuit-formed spectroscopy scheme picture with this spectroscopy scheme, carry out the Frequency Band Selection mechanism of the arbitrary value that (step) in successive or stage select while switching.

The 2nd invention is characterised in that, the wavelength of switching amplitude that is provided for changing the frequency range of being selected by above-mentioned wavelength selection mechanism of setting switches the amplitude set mechanism.

The 3rd invention is characterised in that, is loaded into picture pick-up device in the endoscope in utilization, forms in the endoscope apparatus of colour picture signal of observed body, and the storage part of matrix data that storage constitutes the frequency range of spectroscopy scheme picture is set; Utilize the matrix data of this storage part, carry out the matrix operations based on above-mentioned colour picture signal, the spectroscopy scheme picture of spectroscopy scheme picture that forms the frequency range of selecteed arbitrary value forms circuit; To look like to form a plurality of frequency ranges of circuit-formed spectroscopy scheme picture with this spectroscopy scheme, set, select the wavelength selection mechanism of the wavelength set value of these arbitrary values while switching as a plurality of wavelength set values.

The 4th invention is characterised in that, above-mentioned wavelength selection mechanism, can with under monochromatic mode, form spectroscopy scheme as the time single frequency band, select to carry out like that as above-mentioned wavelength set value.

The 5th invention is characterised in that, the wavelength set value that available above-mentioned wavelength selection mechanism is selected comprises the wavelength set value of the difference that is used to describe oxyhemoglobin and deoxy haemachrome and is used to describe the wavelength set value of difference of blood and carotene or the wavelength set value of blood and cytoplasmic difference.

By above-mentioned formation, try to achieve the λ 1 of wavelength arrowband (composition), λ 2, λ 3 signals in order to utilize matrix operations from rgb signal, (matrix data that coefficient settings value p1～p61) forms, the computing that is stored in the blood processor side is with in the memorizer for example will to cut apart 61 frequency range parameters of the frequency range from 400nm to 700nm at interval with 5nm.And, by wavelength selection mechanism, if the operator selects 3 frequency ranges (1 frequency range also can), then from above-mentioned memorizer, read the matrix data of corresponding these 3 frequency ranges, form in the circuit at the spectroscopy scheme picture, form λ 1, λ 2, λ 3 signals formed by the rgb signal of outputs such as this matrix data and DSP,, form the spectroscopy scheme picture again according to these λ 1, λ 2, λ 3 signals.

In above-mentioned wavelength selection mechanism, utilize and to design each switch of the guidance panel in blood processor, the operation of keyboard, can enough 1nm amplitudes successive or with the amplitude step of 5nm, 10nm, 20nm etc. switch, the frequency range of selection above-mentioned λ 1, λ 2, λ 3.And this switching amplitude can utilize switching amplitude configuration switch to select.

In addition, in the formation of the 3rd～5 invention, utilization is as switch of wavelength selection mechanism etc., can select to be used to describe blood vessel the wavelength set value, describe cancerous tissue etc. particular organization the wavelength set value and also describe oxyhemoglobin and poor, the blood of deoxy haemachrome and the difference of carotene or the wavelength set value of blood and cytoplasmic difference etc., can be easy to form with the spectroscopy scheme picture of specific target as purpose.

By endoscope apparatus of the present invention, by selecting frequency range with the switching amplitude of setting arbitrarily, in addition by selecting predefined wavelength set value, can be easily and select the frequency range of the spectroscopy scheme picture that is used to depict desired destination rapidly, it is first-class that the spectroscopy scheme of depicting blood vessel, particular organization, oxyhemoglobin and deoxy haemachrome difference etc. is looked like to be presented at monitor, provides useful information to diagnosis.

The 6th invention of the present invention is characterized in that, in above-mentioned the 1st invention, also possesses the wavelength storing mechanism of storage by the above-mentioned frequency range of above-mentioned wavelength selection mechanism selection.

In addition, the 7th invention of the present invention is characterized in that, in above-mentioned the 3rd invention, is the corresponding situation that adopts a plurality of frequency ranges, also possesses the wavelength storing mechanism of a plurality of frequency ranges of the above-mentioned wavelength set value of conduct that storage selected by above-mentioned wavelength selection mechanism.

Also have the above-mentioned wavelength storing mechanism in the endoscope apparatus of the present invention, outside the zone of the above-mentioned frequency range of storage, preferably also possess the default data memory area of the initial set value (default value) that is stored in the frequency range of selecting in the wavelength selection mechanism.

In addition, above-mentioned wavelength storing mechanism outside the zone of the above-mentioned frequency range of storage, preferably also possesses the change wavelength storage area that storage keeps the frequency range that the quilt after from then on read in the zone changes.Under such situation, endoscope apparatus of the present invention preferably has and can will be stored in the frequency range of above-mentioned change wavelength storage area, writes the formation in the zone of the above-mentioned frequency range of storage.

By above-mentioned endoscope apparatus of the present invention, the frequency range of selecting by wavelength selection mechanism according to the storage that possesses or as the wavelength storing mechanism of a plurality of frequency ranges of wavelength set value, can with for clinicist's etc. device operator self, think the best frequency range of once selecting storage, be kept in this wavelength storing mechanism.Therefore, when its device user form after next time, show spectroscopy scheme as the time, can read and be kept at frequency range wherein and re-use, so for the device user, can form, show the spectroscopy scheme picture of the easiest observation rapidly.

In addition, especially, wavelength storing mechanism in the endoscope apparatus of the present invention, outside the zone of the above-mentioned frequency range of storage, also possess under the situation of default data memory area of the initial set value that is stored in the frequency range of selecting in the wavelength selection mechanism, can read the initial set value of frequency range therefrom and be used.If like that, device operator can repeatedly be changed the frequency range of selection, chaotic, do not know under the situation of the frequency range which is best suited for concerning own, clear away confusion by the mode that makes frequency range turn back to the initial set value of benchmark.

In addition, above-mentioned wavelength storing mechanism, outside the zone of storage frequency range, also possessing storage, keeping zone from then on to read under the situation of change wavelength storage area of the frequency range that is changed the back, owing to utilize this change wavelength storage area, carry out the change operation of frequency range, so can prevent to be write as the generation of the situation that is not suitable for of value by mistake in the frequency range of the region memory storage of storing frequency range.

In addition, the object of the present invention is to provide a kind of electronic endoscope apparatus that can carry out the diagnosis of normal image and expectation easilier with the handover operation of image.

The 8th invention of the present invention is can be with the normal image of organism mucosa, with by based on the matrix operations (spectroscopy scheme looks like to infer computing) of the wavelength set value of from above-mentioned a plurality of wavelength set values, selecting, the diagnosis image that obtains as the arrowband spectroscopy scheme picture of organism mucosa, switch the electronic endoscope apparatus of demonstration.Its formation possesses the up-to-date wavelength set value storing mechanism of the selecteed up-to-date wavelength set value of storage, when when using image switching, showing the diagnosis image of the up-to-date wavelength set value of corresponding stored in up-to-date wavelength set value storing mechanism to diagnosis from normal image.

Above-mentioned up-to-date wavelength set value storing mechanism, even the driving power that contains at this fujinon electronic video endoscope is under the OFF state, the standby mechanism that the storage of the above-mentioned up-to-date wavelength set value in this up-to-date wavelength set value storing mechanism can be kept.

Also have, above-mentioned storing mechanism is not limited to store the situation of wavelength set value itself, represents that in fact the relevant information of this wavelength set value can both be stored.

The inventor is in the diagnosis of adopting the organism mucosa can make the electronic endoscope apparatus that the multiple diagnosis that utilizes above-mentioned arrowband spectroscopy scheme picture to generate shows with image and normal image, from normal image when diagnosis is carried out image switching with image, obtained making and switched a lot of practical intelligence that the diagnosis that is shown before the above-mentioned normal image is come out with pictorial display, according to these knowledge, finished the present invention.That is to say, in above-mentioned electronic endoscope apparatus, in case determine to the suitable certain wavelengths setting value of the diagnosis of organism mucosa, switch a lot of relevant knowledge that shows between the image repeatedly according to using, finished the present invention in the diagnosis of normal image and corresponding above-mentioned certain wavelengths setting value.

Electronic endoscope apparatus of the present invention, it possesses the up-to-date wavelength set value storing mechanism of the selecteed up-to-date wavelength set value of storage, when from normal image to diagnosis when using image switching, demonstrate the diagnosis image of the up-to-date wavelength set value of corresponding stored in up-to-date wavelength set value storing mechanism, so can easierly carry out the handover operation of the diagnosis of normal image and expectation with image.

That is to say that general, when image switching was used in diagnosis, the diagnosis image of wanting to show was to show that the diagnosis that shows before the above-mentioned normal image is very high with the probability of image from normal image.Under such situation, use the demonstration of image according to the diagnosis of the wavelength set value of corresponding stored in storing mechanism, can realize the diagnosis expected demonstration with image, thus can easier realization from normal image to the diagnosis of expectation handover operation with image.

In addition, above-mentioned up-to-date wavelength set value storing mechanism, if even the driving power that contains at this fujinon electronic video endoscope is under the OFF state, the standby mechanism that the storage of the above-mentioned up-to-date wavelength set value in this up-to-date wavelength set value storing mechanism can be kept just can more reliable realization show the action of the diagnosis of above-mentioned expectation with image.

Description of drawings

Fig. 1 is the block diagram of expression about the formation of the endoscope apparatus of one embodiment of the present invention.

Fig. 2 is that the guidance panel of blood processor of the endoscope apparatus of expression pie graph 1 constitutes and the figure of the example of wavelength set value.

Fig. 3 is wavelength information viewing area in the detector of endoscope apparatus of presentation graphs 1 and the figure that shows example thereof.

Fig. 4 be with the spectral sensitivity characteristic of former colour pattern CCD together, the curve chart of an example of the frequency range of expression spectroscopy scheme picture.

Fig. 5 be with the organism reflecting spectrum together, the curve chart of an example of the frequency range of expression spectroscopy scheme picture.

Fig. 6 is the figure of expression with the wavelength switching state of the wavelength change-over switch operation of the endoscope apparatus of Fig. 1.

Fig. 7 is the figure of the wavelength set value that is illustrated in the endoscope apparatus of Fig. 1, selected by monochromatic mode.

Fig. 8 is other the key diagram of example that the wavelength set value in the setting value change-over switch of expression embodiment is switched.

Fig. 9 is the block diagram that the summary of the electronic endoscope apparatus of expression embodiments of the present invention constitutes.

Figure 10 is the figure of the concrete example of expression wavelength set value.

Figure 11 is the amplification block diagram that the summary of expression variation 1 constitutes.

Figure 12 is the amplification block diagram that the summary of expression variation 2 constitutes.

The specific embodiment

Fig. 1 represents the formation about the electronic endoscope apparatus of embodiment.This electronic endoscope apparatus is such as shown, oscillograph (fujinon electronic video endoscope) 10, is about to the endoscopic main body part and connects into the formation that can freely load and unload with respect to blood processor 12, manages herein on the device 12, for example disposes the light source 14 of the coloured light that turns white.Also have, also there is the situation of the light supply apparatus that is configured to split in this light source 14.On above-mentioned oscillograph 10, its leading section is provided with solid photographic device CCD15, as this CCD15, for example can adopt complementary color type that contains Mg (fuchsin), Ye (yellow), Cy (cyan), G (green) light filter on the shooting face or the former colour pattern that contains the light filter of RGB.

For this CCD15, be provided with according to synchronizing signal, when forming the CCD drive circuit 16 of driving pulse, image (image) signal of this CCD15 input of sampling and CDS/AGC (control of correlated double sampling/automatic gain) circuit 17, the A/D changer 18 that amplifies are set.In addition, the various circuit in the configuration control oscillograph 10 and and blood processor 12 between the microcomputer 20 of communication.Also have, its front end is provided with illuminating window 23 on oscillograph 10, and this illuminating window 23 is connected to above-mentioned light source 14 by light guide 24.

On the other hand, on blood processor 12, setting for by the picture signal after the digital conversion, carry out the DSP (digital signal processor) 25 of various Flame Image Process, on this DSP25, form and export the next y/c signal of output signal of above-mentioned CCD15 by brightness (Y) signal and aberration [C (R-Y), (B-Y)] signal formation.In an embodiment, the formation that can select and common image (dynamic image and rest image) and the spectroscopy scheme picture (dynamic image and rest image) of demonstration, on above-mentioned DSP25, by implementing to form the switch 26 (on a terminal) that common image still forms the switching of spectroscopy scheme picture, the 1st complexion changed is set changes circuit 28, change on the circuit 28 at this 1st complexion changed, will be transformed to rgb signal by Y (brightness)/C (aberration) signal of above-mentioned DSP25 output.Also have, above-mentioned DSP25 is also configurable in oscillograph 10 sides.

Change the back segment of circuit 28 at this 1st complexion changed, be provided with: be used for the color space transformation treatment circuit 29 (be equivalent to the spectroscopy scheme picture and form circuit) that spectroscopy scheme looks like to carry out the spectroscopy scheme image signal of matrix operations, the selecteed wavelength X 1 of output, λ 2, λ 3; Selection is by any one mode selector 30 in spectroscopy scheme picture (monochromatic mode) of 1 each frequency range (arrowband) and the spectroscopy scheme picture of being made up of 3 frequency ranges (3 color pattern) (in this mode selector, also can be provided with the 2 color patterns of selecting 2 colors); For the picture signal (λ 1s, λ 2s, λ 3s) that makes 1 frequency range or 3 frequency ranges, realize the processing of corresponding rgb signal in the past, Rs, Gs, Bs signal are changed circuit 31 as input, the 2nd complexion changed that this Rs, Gs, Bs signal are transformed into y/c signal; And carry out other various signal processing (mirror image processing, produce cover, character generation etc.) signal processing circuit 32, D/A changer 33.

In addition, in the inside of the blood processor 12 of Fig. 1, be arranged on and oscillograph 10 between same timed unit 12 inside that communicate each circuit, from memorizer 36 (being equivalent to storage part) sensor matrix (coefficient) data, supply with the microcomputer 35 of above-mentioned color space transformation treatment circuit 29.On above-mentioned memorizer 36, according to rgb signal, storage is used to form matrix (coefficient) data (form) of spectroscopy scheme picture.In the present embodiment, it is as shown in table 1 below to be stored in an example of matrix data in the above-mentioned memorizer 36.

[table 1]

Parameter	kpr	kpg	kpb
				p1	0.000083	-0.00188	0.003592
. . .	. . .	. . .	. . .
				p18	-0.00115	0.000569	0.003325
p19	-0.00118	0.001149	0.002771
				p20	-0.00118	0.001731	0.0022
p21	-0.00119	0.002346	0.0016
				p22	-0.00119	0.00298	0.000983
p23	-0.00119	0.003633	0.000352
				. . .	. . .	. . .	. . .
p43	0.003236	0.001377	-0.00159
				p44	0.003656	0.000671	-0.00126
p45	0.004022	0.000068	-0.00097
				p46	0.004342	-0.00046	-0.00073
p47	0.00459	-0.00088	-0.00051
				p48	0.004779	-0.00121	-0.00034
p49	0.004922	-0.00148	-0.00018
				p50	0.005048	-0.00172	-0.000036
p51	0.005152	-0.00192	0.000088
				p52	0.005215	-0.00207	0.000217
. . .	. . .	. . .	. . .
				p61	0.00548	-0.00229	0.00453

The matrix data of above-mentioned table 1, for example by cut apart at interval with 5nm from 400nm to 700nm after parameter (coefficient settings value) p1～p61 of 61 frequency ranges form.These parameter p 1～p61 is by the coefficient k that is used for matrix operations _Pr, k _Pg, k _Pb(p is equivalent to p1～p61) and constitutes.

And, in above-mentioned color space transformation treatment circuit 29, according to above-mentioned coefficient k _Pr, k _Pg, k _PbRgb signal with changed circuit 28 outputs by the 1st complexion changed carries out the matrix operations of following formula 1, forms λ 1s, λ 2s, λ 3s.

[formula 1]

$\left[\begin{array}{c}\mathrm{\λ}1\\ \mathrm{\λ}2\\ \mathrm{\λ}3\end{array}\right]=\left[\begin{array}{ccc}{k}_{1r}& k_{1g}& k_{1b}\\ k_{2r}& k_{2g}& k_{1b}\\ k_{3r}& k_{3g}& k_{3b}\end{array}\right]\×\left[\begin{array}{c}R\\ G\\ B\end{array}\right]$

That is to say, as wave band λ 1, the λ 2, the λ 3 that constitute the spectroscopy scheme picture, for example when selecting 500nm, 620nm, 650nm respectively, as coefficient (k _Pr, k _Pg, k _Pb), the coefficient (0.005152 ,-0.00192,0.000088) of the coefficient (0.004022,0.000068 ,-0.00097) of the coefficient (0.00119,0.002346,0.0016) of the parameter p 21 of the corresponding centre wavelength 500nm in 61 parameters of employing table 1, the parameter p 45 of corresponding centre wavelength 620nm and the parameter p 51 of corresponding centre wavelength 650nm carries out above-mentioned matrix operations.Also have, such parameter is according to the combination that is stored in the wavelength in the wavelength set memorizer 42 described later, reads from memorizer 36, sets forth in the back about this point.

In addition, on another lead-out terminal of above-mentioned switch 26, connect and to be used to form non-spectral image but the color-signal processing circuit 38 of common coloured image, and D/A changer 39 connects these color-signal processing circuits 38.

Microcomputer 35 is except above-mentioned memorizer 36, also connected by guidance panel 41, wavelength set value memorizer 42 and the input part 43 be made up of keyboard etc.The expression that Fig. 2 is detailed aforesaid operations panel 41, on this guidance panel 41, integrate and for example be provided with being used to shown in skeleton diagram and select the setting value selector switch 41a of a～h wavelength set value; Be used to select the wavelength-selective switches 41b of each centre wavelength of frequency range λ 1, λ 2, λ 3; Set the switching amplitude configuration switch 41c of the amplitude that wavelength that wavelength-selective switches 41b thus selects switches; The mode selector switch 41d of the monochromatic mode of enforcement selection single wavelength and the switching of 3 color patterns; Be used to make the frequency range of whole wavelength set value of a～h to get back to all reset switch 41e of initial value described later; Be used for making the frequency range of 1 wavelength set value of a～h to get back to a part of reset switch 41f of initial value; Be used for that wavelength set value a～h that the device user with each clinicist etc. generates is written to wavelength set value memorizer 42 and again from that doctor's page switch 41g that reads; Be used for the wavelength set value is stored, is kept at the preservation switch 41h of wavelength set value memorizer 42; And the spectroscopy scheme picture that indication spectroscopy scheme picture forms forms switch 41j.Also have, also this spectroscopy scheme picture can be formed switch 41j and be arranged on oscillograph 10 sides.

Wavelength-selective switches 41b, irrelevant with the frequency range of the wavelength set value that sets by setting value selector switch 41a, can select centre wavelength.In addition, also the selection frequency range can be switched in the value of the wavelength set value selected by setting value selector switch 41a position to start with.And above-mentioned microcomputer 35 is supplied with color space transformation treatment circuit 29 with above-mentioned switch 41a～frequency range λ 1, the λ 2 of 41e signal selection, the matrix data of λ 3.Also have, the function of these switches all can be by the key assignments of keyboard.

Below, describe at the effect of the electronic endoscope apparatus of the present embodiment that contains above-mentioned formation.At first, the formation from normal image and spectroscopy scheme picture describes.As shown in Figure 1, in oscillograph 10, the CCD15 that drives by the CCD drive circuit 16 observed body of making a video recording, output image pickup signal.This image pickup signal after the amplification of accepting to be undertaken by correlated double sampling and automatic gain control, carries out the A/D conversion in A/D changer 18 in CDS/AGC circuit 17, be input to as digital signal among the DSP25 of blood processor 12.

In this DSP25, for output signal from oscillograph 10, when carrying out the gamma processing, for the signal that the light filter by Mg, Ye, Cy, G obtains, carry out complexion changed and change processing, form the y/c signal of forming by brightness (Y) signal and aberration (R-Y, B-Y) signal.The output of this DSP25, usually supply with color-signal processing circuit 38 by switch 26, utilize this circuit 38 accept mirror image processing, produce cover and the predetermined process of character generation etc. after, after being transformed into analogue signal, supply with monitor 34 as shown in Figure 3 by D/A changer 39.Thus, the coloured image that on this monitor 34, shows common observed body.

On the other hand, form switch 41j if press the spectroscopy scheme picture of guidance panel 41 (being equivalent to wavelength selection mechanism) as shown in Figure 2, switch 26 will make the y/c signal of DSP25 output switch to the state that the 1st complexion changed changes circuit 28 of supplying with, by this circuit 28, above-mentioned y/c signal is transformed to rgb signal.This rgb signal is supplied to color space transformation treatment circuit 29, in this color space transformation treatment circuit 29, is used for the matrix operations of the above-mentioned formula 1 that the spectroscopy scheme picture forms according to rgb signal and matrix data.That is to say, in the formation of this spectroscopy scheme picture,, set 3 frequency ranges of λ 1, λ 2, λ 3 by the operation of guidance panel 41 described later, microcomputer 35 is read the matrix data of corresponding its 3 frequency ranges from memorizer 36, is entered in the color space transformation treatment circuit 29.

For example, when 3 frequency range λ 1, λ 2, λ 3 selected 500nm, 620nm, 650nm, adopt the parameter p 21 of the table 1 of corresponding each wavelength, the coefficient of p45, p51, facial 2 matrix operations forms spectroscopy scheme image signal λ 1s, λ 2s, λ 3s under the rgb signal utilization.

[formula 2]

$\left[\begin{array}{c}\mathrm{\λ}1s\\ \mathrm{\λ}2s\\ \mathrm{\λ}3s\end{array}\right]=\left[\begin{array}{ccc}-0.00119& 0.002346& 0.0016\\ 0.004022& 0.000068& -0.00097\\ 0.005152& -0.00192& 0.000088\end{array}\right]\×\left[\begin{array}{c}R\\ G\\ B\end{array}\right]$

When mode selector 30 is selected 3 color patterns, above-mentioned spectroscopy scheme image signal λ 1s, λ 2s, λ 3s are input to the 2nd complexion changed as the 3 color image signals of Rs, Gs, Bs respectively change in the circuit 31.In addition, when selecting monochromatic mode, among spectroscopy scheme image signal λ 1s, λ 2s, the λ 3s any one as Rs, Gs, Bs signal, is input to the 2nd complexion changed and changes in the circuit 31.Change in the circuit 31 at this 2nd complexion changed, the 3 color image signals of Rs, Gs, Bs are transformed to y/c signal (Y, Rs-Y, Bs-Y), and this y/c signal is imported in above-mentioned monitor 34 etc. by signal processing circuit 32 and D/A changer 33.

As mentioned above, be presented at the spectroscopy scheme picture on monitor 34 grades, constitute by the colour content of Fig. 4 and frequency range shown in Figure 5.That is to say that Fig. 4 is on the spectral sensitivity characteristic R, G, B at the light filter of former colour pattern CCD15, overlap to form 3 frequency range λ 1, λ 2, λ 3 concept maps of spectroscopy scheme picture.In addition, Fig. 5 is the concept map of overlapping 3 frequency range λ 1, λ 2, λ 3 on the reflecting spectrum of organism.The spectroscopy scheme image signal λ 1s, λ 2s, the λ 3s that are made up of as previously shown parameter p 21, p45, p51 are as shown in Figure 5, respectively with 500nm, 620nm, 650nm be centre wavelength ± chrominance signal of the frequency range of 10nm left and right sides scope, shown by the colour cell of these 3 frequency ranges and closed the spectroscopy scheme picture (dynamic image and rest image) that constitutes.

Also have, switch 26 is in and makes the y/c signal of DSP25 output supply with the state that the 1st complexion changed changes circuit 28, when form, show spectroscopy scheme as the time, form switch 41j if press the spectroscopy scheme picture of guidance panel shown in Figure 2 41, switch 26 will be got back to the state that makes above-mentioned y/c signal supply with color-signal processing circuit 38, demonstrates the chromatic normal image as dynamic image or rest image.

Below, describe at the selection of above-mentioned frequency range λ 1, λ 2, λ 3.In the present embodiment, as shown in Figure 2, as the wavelength set value of λ 1, λ 2, λ 3, the typical set value a of (nm, following same) for example with 400,500,600; Be used to depict 470,500,670 blood vessel B1 setting value b of blood vessel; Be used to depict 475,510,685 blood vessel B2 setting value c of blood vessel equally; Be used to depict particular organization 440,480,520 organize E1 setting value d; Be used to equally to retouch out particular organization 480,510,580 organize E2 setting value e; Be used to depict 400,430,475 haemachrome setting value f of oxyhemoglobin and deoxy haemachrome difference; Be used to depict blood-carotene setting value g of 415,450,500 of blood and carotene difference; Be used to depict 8 wavelength set values of blood-Cytoplasm setting value h of 420,550,600 of the difference of blood and Cytoplasm,, store among the 1st regional 42a of wavelength set value memorizer 42 as shown in Figure 2 as acquiescence wavelength set value.

When the shipment of the workshop of electronic endoscope apparatus, the acquiescence wavelength set value that is stored in above-mentioned the 1st regional 42a also is stored among the 2nd regional 42b of wavelength set value register 42, if switch on launcher thereafter earlier, the acquiescence wavelength set value that then is stored in this 2nd regional 42b is selected by microcomputer 35.And, forming switch 41j if press the spectroscopy scheme picture of guidance panel 41 as shown in Figure 2, the typical set value a in the above-mentioned selecteed wavelength set value is presented among the wavelength information viewing area 34s in the monitor 34 of Fig. 3.At this moment, if press mode selector switch 41d, select 3 color patterns, then from memorizer 36, read λ 1=400nm, the λ 2=500nm of corresponding typical set value a, each parameter of λ 3=600nm, again those parameters are input in the color space transformation treatment circuit 29.Color space transformation treatment circuit 29 utilizes the parameter of input to carry out above-mentioned matrix operations, forms spectroscopic signal λ 1s, λ 2s, λ 3s.And the spectroscopy scheme of being made up of these spectroscopy scheme image signals λ 1s, λ 2s, λ 3s looks like to be presented in the monitor 34 of Fig. 3.

In addition, clinicist's etc. device operator, the setting value selector switch 41a that contains on the guidance panel 41 by application drawing 2; Can select arbitrarily to give tacit consent to the wavelength set value beyond wavelength set value b～h, microcomputer 35 is presented among the wavelength information viewing area 34s in the monitor 34 of Fig. 3 the wavelength set value of such selection.Meanwhile, from memorizer 36, read frequency range λ 1, the λ 2 of corresponding selecteed wavelength set value, each parameter of λ 3, again these parameters are input in the color space transformation treatment circuit 29 by microcomputer 35.Color space transformation treatment circuit 29 utilizes the parameter of input to carry out above-mentioned matrix operations, forms spectroscopy scheme image signal λ 1s, λ 2s, λ 3s; And the spectroscopy scheme of being made up of these spectroscopy scheme image signals λ 1s, λ 2s, λ 3s looks like to be presented in the monitor 34 of Fig. 3.

Also have, setting value selector switch 41a is made up of up switch that contains triangle operating portion up and the downing switch that contains triangle operating portion down as shown in Figure 2.Whenever press the former once, the wavelength set value is selected a → h → g one by one Relative with it, whenever press the latter once, the wavelength set value is selected a → b → c one by one ...

In addition, during in selecting above-mentioned wavelength set value a～h one, the operator is by operative wavelength selector switch 41b, frequency range λ 1, the λ 2 of the wavelength set value of its selection, each value of λ 3 can be changed to arbitrary value.When this frequency range change, can change wavelength by switching amplitude configuration switch 41c (be equivalent to wavelength and switch the amplitude set mechanism) and switch amplitude.That is to say, by rotating the knob of switching amplitude configuration switch 41c, can set the switching in the successive or stage the 1nm amplitude that is similar to continuous switching of resembling, 5nm amplitude that step is switched, 10nm amplitude, the 20nm amplitude.Also have, when for example switching, become and in 400～700 scope, set 301 frequency ranges with 1nm, the matrix data of corresponding this 301 frequency range of generation (p ' 1～p ' 301).

Fig. 6 represents the selection of this frequency range, when setting above-mentioned 5nm amplitude, as as shown in the switching of λ 1, switch resembling 400 → 405 → 410, when switching the amplitude of above-mentioned 20nm, as as shown in the switching of λ 3, to switch resembling 600 → 620 → 640, this value is presented among the wavelength information viewing area 34s of monitor 34.Like this, has the setting that makes the frequency range when the seeking target advantage easily that becomes.

The expression that Fig. 3 is detailed show state among the above-mentioned wavelength information viewing area 34s.In the present embodiment, by the character generation in the above-mentioned signal processing circuit 32 etc., shown in Fig. 3 (A), in the wavelength information viewing area 34s of the right lower quadrant that is set in monitor 34 etc., shown wavelength information.That is to say, on the 34s of this wavelength information viewing area, shown in Fig. 3 (B), below the literal of λ 1, λ 2, λ 3 etc., shown selecteed wavelength value (nm).Can shown in figure (C), be that wave length calibration, the longitudinal axis are sensitivity also perhaps with the transverse axis, the visual selecteed frequency range of demonstration in movable coordinate diagram (corresponding diagram 4 curves).

Also have, as above-mentioned, with frequency range λ 1, the λ 2 of wavelength set value, the processing that λ 3 changes to arbitrary value, the operating area 42d of utilization wavelength set value memorizer 42 as shown in Figure 2, temporary transient data carry out by storing there.

Mode selector switch 41d shown in Figure 2 is the switching of carrying out monochromatic mode and 3 color patterns, if press this mode selector switch 41d during the action of 3 color patterns, then switch to monochromatic mode, the whole setting of frequency range λ 1, λ 2, λ 3 become to resemble 470,470,470 identical value by microcomputer 35.And, in monitor 34, as shown in Figure 7, show common frequency range.Also have,, also can select value arbitrarily by above-mentioned wavelength-selective switches 41b even on this common frequency range.

Here, can be the keypress function of keyboard with the replacement of function of the part of the Switch on the aforesaid operations panel 41, can with whole replacement of function the keypress function of keyboard also.

As mentioned above, several among wavelength set value a～h, when changing its frequency range λ 1, λ 2, λ 3, if press the preservation switch 41h that the guidance panel 41 of Fig. 2 is contained, the new wavelength set value a～h that comprises its change will write, be saved on the 2nd regional 42b of wavelength set value memorizer 42 by microcomputer 35.Such preservation forms directly, shows that to utilizing its new wavelength set value a～h the situation of spectroscopy scheme picture is favourable.

In addition, resemble the new wavelength set value a～h that generates above-mentioned, for example preservation switch 41h and the doctor's page switch 41g by containing on the guidance panel 41 of pressing Fig. 2 simultaneously carries out new storage, preservation by microcomputer on the 3rd regional 42c of wavelength set value memorizer 42.At this moment, on monitor shown in Figure 3 34, the notice that can eject the name of the device operator of pointing out input to carry out its preservation shows.Thus, utilize the input part 43 of keyboard shown in Figure 1 etc., the name of for example input [Dr. * *] etc.The name of microcomputer 35 corresponding these inputs is stored in above-mentioned new wavelength set value a～h on the above-mentioned the 3rd regional 42c.In the present embodiment, as an example, can be with maximum 10 groups wavelength set value a～h, with the name difference corresponding stored of each device operator.

Storage, be kept at the wavelength set value a～h on the 3rd regional 42c of above-mentioned wavelength set value memorizer 42, the doctor's page switch 41g by containing on the push panel 41 can read from the 3rd regional 42c and use.That is to say, whenever press this doctor's page switch 41g next time, just can resemble and select the 1st group wavelength set value a～h, wavelength set value a～h of the 2nd group, wavelength set value a～h of the 3rd group by microcomputer 35 ... select the wavelength set value like that in turn, from the 3rd regional 42c, read, store among the above-mentioned the 2nd regional 42b as change wavelength storage area.And by microcomputer 35, frequency range λ 1, the λ 2 that the corresponding wavelength of this storage can be set value, each parameter of λ 3 are read from memorizer 36, and the spectroscopy scheme picture of being made up of its parameter forms, with above-mentioned identical.

Also have, about resembling the wavelength set value a～h that selects above-mentioned, as (B) of Fig. 3 and (C), in the 34s of the wavelength information viewing area of monitor 34, for example in the demonstration of [i] that expression spectroscopy scheme picture forms, carry out the demonstration of producer's name and setting value name with the form of [Dr. * * b. blood vessel B1].Thus, can be confirmed to be according to which wavelength set value and form, show the spectroscopy scheme picture.

Forming, showing on the spectroscopy scheme picture of easily observing clinically, optimal frequency range λ 1, λ 2, λ 3 are often because the difference of clinicist's etc. device operator and different, but as described above, if each each device operator generates, preserves 1 group of wavelength set value a～h, it is read, uses, just can be rapidly and simply form each device operator spectroscopy scheme picture of easy observation.

Also have, for the wavelength set value, run into phenomenon above-mentioned [Dr. * *. blood vessel B1] during such demonstration, if its wavelength set value is under the situation of above-mentioned acquiescence wavelength set value, for example use white, under the situation that the acquiescence wavelength is changed, for example carry out chromatograph and show with green such mode, owing to know the resume of wavelength set value, so very convenient.

In addition, the wavelength set value a～h that reads from the 3rd regional 42c of above-mentioned wavelength set value memorizer 42, the situation of the acquiescence wavelength set value a～h that reads from the 1st regional 42a zone with foregoing change is identical, can carry out the change of frequency range λ 1, λ 2, λ 3 for part or all.The wavelength set value a～h that is changed like this by the preservation switch 41h that contains on the push panel 41, covers among the 3rd regional 42c of the wavelength set value memorizer 42 that is saved in Fig. 1 by microcomputer 35.That is to say that the wavelength set value a～h that is then changed can be saved as the 1st group new wavelength set value if its wavelength set value is when for example being the wavelength set value of the 1st group of being generated by [Dr. * *].

Also have, resemble the wavelength set value a～h that is changed above-mentioned, by preservation switch 41h and the doctor's page switch 41g that contains on the while push panel 41, can be on the 3rd regional 42c of the wavelength set value memorizer 42 of Fig. 1 store, preserve as the wavelength set value of the group of new work.On the monitor 34 as shown in Figure 3, the notice that also can eject the name of the device operator of pointing out input to implement its preservation shows at this moment.Therefore, utilize the input part 43 of keyboard shown in Figure 1 etc., for example can import the name of [Dr. 0 0] etc.The name of microcomputer and this input is corresponding, and newly-generated wavelength set value a～h is stored on the above-mentioned the 3rd regional 42c.Like this, for example the shallow device operator of clinical experience can be continued to employ wavelength set value a～h that the abundant device operator of a part of clinical experience makes, and generates the wavelength set value that is fit to oneself simply.

Also have, substitute above-mentioned pressing like that simultaneously and preserve switch 41h and doctor's page switch 41g, when only pressing preservation switch 41h, make and occur on the above-mentioned monitor 34 [will covering? ] demonstration, relative therewith, when the input that obtains agreeing from input part 43, cover the wavelength set value of the group of reading the wavelength set value, when obtaining representing the input of non-agreement, make it store, preserve the wavelength set value of the different group of new group with reading the wavelength set value.

Below, describe at the resetting of wavelength set value of the 2nd regional 42b that is stored in wavelength set value memorizer 42.As above-mentioned, change is stored in the acquiescence wavelength set value among this 2nd regional 42b, after forming, show the spectroscopy scheme picture in view of the above, if all reset switch 41e that contains on the push panel, microcomputer 35 can be read the acquiescence wavelength set value among the 1st regional 42a that is stored in wavelength set value memorizer 42, and it is stored among the 2nd regional 42b.

This reset operation for example must carry out after forming, showing the spectroscopy scheme picture.Like that, generation based on the new wavelength set value of the wavelength set value that is stored in the 2nd regional 42b, no matter device operator is replaced for Whom, owing to must carry out from acquiescence wavelength set value, and all exist as the wavelength set value on basis several times, so can prevent the confusion of the generation of new wavelength set value.

In addition, resemble and change the acquiescence wavelength set value that is stored in above-mentioned the 2nd regional 42b above-mentioned, after forming, show the spectroscopy scheme picture in view of the above, if press a part of reset switch 41f that contains on the guidance panel 41 of Fig. 2, microcomputer 35 can replace being used for 1 group of wavelength set value (any one of a～h) that its spectroscopy scheme picture forms, and the wavelength set value (any one among a～h) on the same group in the acquiescence wavelength set value that is stored in the 1st regional 42a is stored among the 2nd regional 42b.Like that, in various change wavelength set values (any one among a～h), chaotic, do not know which is under the situation of best frequency range λ 1, λ 2, λ 3, by getting back to the acquiescence wavelength set value on basis, can clear away confusion.

Below, the resetting of wavelength set value of the 3rd regional 42c that is stored in wavelength set value memorizer 42 described.Change is stored in the wavelength set value of each device operator of the 3rd regional 42c as mentioned above, after forming, show the spectroscopy scheme picture in view of the above, if press all reset switch 41e that contains on the guidance panel 41 of Fig. 2, microcomputer 35 can be read the acquiescence wavelength set value of the 1st regional 42a that is stored in wavelength set value memorizer 42, and it is stored among the 3rd regional 42c.

Perhaps as above-mentioned, change is stored in the wavelength set value of each device operator of above-mentioned the 3rd regional 42c, form in view of the above, show after the spectroscopy scheme picture, if press a part of reset switch 41f that contains on the guidance panel 41 of Fig. 2, microcomputer 35 replacements are used for 1 group of wavelength set value (any one among a～h) of the formation of spectroscopy scheme picture, and the wavelength set value (any one among a～h) on the same group in the acquiescence wavelength set value that is stored in the 1st regional 42a is stored among the 3rd regional 42c.

Implement in two above reset operations which, among in various change wavelength set value a～h any one or a plurality of frequency range λ 1, λ 2, the λ 3, chaotic, do not know which is under the situation of best frequency range λ 1, λ 2, λ 3, the acquiescence wavelength set value of benchmark is got back in utilization, can clear away confusion.

The example of other when Fig. 8 represents with above-mentioned setting value selector switch 41a wavelength switching setting value, this example is by above-mentioned setting value selector switch 41a, and the setting value (4 setting values, 5 setting values etc.) of defined amount is carried out in the mode of cyclical-transformation.For example, as shown in the figure, set a (standard) setting value, b (blood vessel B1) setting value, c (blood vessel B2) setting value and d (tissue E1) setting value (setting value of defined amount), but these setting values are carried out in the mode of in turn cyclical-transformation, in addition, replace these b～d setting value,, change the kind of conversion wavelength set value by the setting value e～h (tissue E2, haemachrome, blood-carotene, blood-Cytoplasm etc.) that selects other.Like this, by setting the wavelength set value of frequent use, be easy to carry out the selection of wavelength set value.

In the above-described embodiment, 400nm can be divided into 61 frequency ranges to the frequency range of 700nm selects like that, but as frequency range λ 1, λ 2, λ 3, by selecting to comprise the frequency range of region of ultra-red or the wavelength set value of region of ultra-red only, do not use the cut-off filter in visible light zone, can obtain and shone the akin spectroscopy scheme picture of image that infrared ray obtains in the past.In addition, in endoscope in the past, be to realize that by the exciting light irradiation shooting waits next luminous fluorescence from cancerous tissue, but wavelength set value as above-mentioned λ 1, λ 2, λ 3, by the wavelength of fluorescence of selecting to match, formation is the spectroscopy scheme picture of target with the part of sending fluorescence, has the advantage of the cut-off filter that does not need exciting light this moment.

Also have, in endoscope in the past, carrying out indigo-blue, peacock blue etc. pigment in observed body scatters, shooting is subjected to the tissue of the distribution influence of pigment, wavelength set value as above-mentioned λ 1, λ 2, λ 3, by selecting to depict the frequency range that is subjected to pigment to scatter the tissue that influences, the equal spectroscopy scheme picture of image in the time of also can not needed pigment distribution and pigment to scatter.

Below, at other embodiment of the present invention, utilize drawing to describe.Fig. 9 is the block diagram that the summary of the electronic endoscope apparatus of expression embodiments of the present invention constitutes, and Figure 10 is the figure of the concrete example of expression wavelength set value.

The electronic endoscope apparatus of forming by embodiments of the present invention shown in Figure 9 100, possess: inlay the picture of light filter 12 shooting organism mucosas 1 by colour, obtain the broadband beam split view data Dr of red frequency range, green frequency range and the blue frequency bands of the normal image that constitutes this organism mucosa 1, the image pickup part 110 of Dg, Db; Store predetermined constitute organism mucosa 1 diagnostic image each arrowband spectroscopy scheme picture frequency range (situation as narrow frequency range is described) each wavelength set value Se (a), Se (b) ... wavelength set value storage part 122; From the wavelength set value Se (a), the Se (b) that are stored in wavelength set value storage part 122 ... in, select to be used for the wavelength set value selection portion 124 that above-mentioned spectroscopy scheme looks like to infer the wavelength set value of computing; Storage is used for looking like to infer the matrix data storage part 126 that the branch luminous reflectance of computing is inferred matrix data M with organism mucosa 1 relevant spectroscopy scheme; Wavelength set value by above-mentioned broadband beam split view data Dr, Dg, Db and 124 selections of wavelength set value selection portion, for example look like to infer computing, try to achieve the arrowband beam split view data Db1 of the organism mucosa 1 of corresponding above-mentioned wavelength set value Se (b) represented each frequency range λ b1, λ b2, λ b3, the spectroscopy scheme of Db2, Db3 looks like to infer operational part 128 according to the spectroscopy scheme of inferring matrix data M (b) based on the branch luminous reflectance of corresponding wavelength setting value Se (b); Wavelength set value Se (b) with reference to 124 selections of wavelength set value selection portion, extract the branch luminous reflectance of corresponding this wavelength set value Se (b) and infer matrix data M (b), the branch luminous reflectance of this extraction is inferred matrix data M (b) output to the matrix data extraction unit 132 that spectroscopy scheme looks like to infer operational part 128.

Also have, above-mentioned normal image is the broadband spectroscopy scheme picture of 3 kinds of represented broadband spectroscopy scheme pictures of synthetic wideband beam split view data Dr, Dg, Db.On the other hand, diagnosis is to synthesize the arrowband spectroscopy scheme picture of arrowband spectroscopy scheme as 3 kinds of represented arrowband spectroscopy scheme pictures of data Db1, Db2, Db3 with image.

Also have, above-mentioned electronic endoscope apparatus 100, possess: make the normal image Gt that utilizes the organism mucosa 1 that broadband beam split view data Dr, Dg, Db generate be presented at the normal image display mode in the display device 80 and utilize diagnosis that above-mentioned arrowband beam split view data Db1, Db2, Db3 generate to be presented at diagnosis image display mode in the above-mentioned display device 80, can switch the display mode switching part 134 of demonstration with image Gs; When switching to above-mentioned diagnosis and use image display mode, the up-to-date wavelength set value storage part 136 of the up-to-date wavelength set value that storage wavelength set value selection portion 124 is selected; When implement by display mode switching part 134 forms from the normal image display mode during to the switching of diagnosis usefulness image display mode, the initial stage display setting portion 138 that the diagnosis that makes the wavelength set value of corresponding stored in up-to-date wavelength set value storage part 136 is come out with pictorial display.

As mentioned above, electronic endoscope apparatus 100 is the normal image Gt that switch as the wideband image of organism mucosa 1, look like to infer spectroscopy scheme that operational part 128 carries out with spectroscopy scheme and look like to infer that computing obtains as the diagnosis image Gs of the arrowband spectroscopy scheme picture of organism mucosa 1, be presented in the display device 80 by the wavelength set value selected in the wavelength set value based on a plurality of kinds from be stored in wavelength set value storage part 122.In addition, these electronic endoscope apparatus 100 its formations possess the up-to-date wavelength set value storage part 136 of storage by the up-to-date wavelength set value of wavelength set value selection portion 124 selections, when by display mode switching part 134, make the image that shows to display device 80 when normal image Gt switches to diagnosis with image Gs, by initial stage display setting portion 138 effect, the diagnosis of the wavelength set value of corresponding stored in up-to-date wavelength set value storage part 136 is revealed with image Gs.

This electronic endoscope apparatus 100 also possesses: synthetic wideband beam split view data Dr, Dg, Db, the general image data generating unit 142 of the general image data Dt of generation expression normal image; Synthetic arrowband spectroscopy scheme is as data Db1, Db2, Db3, and the diagnosis diagnosis view data generating unit 144 of the diagnosis of image with view data Ds represented in generation; With the timing of all action of this endoscope apparatus of control 100, synchronous etc. controller 82.

Also have, it is to wait the branch reflective character of corresponding organism mucosa to stipulate in advance by experiment that above-mentioned minute luminous reflectance inferred matrix data.The spectroscopy scheme of inferring matrix data and broadband beam split view data Dr, Dg, Db by the branch luminous reflectance of corresponding specific wavelength setting value looks like to infer computing, can obtain representing the arrowband beam split view data of the arrowband spectroscopy scheme picture of the organism mucosa 1 in each frequency range of above-mentioned certain wavelengths setting value regulation.

In addition, wavelength set value selection portion 124, connect suitable the direction switching push button 124 of the cycling switch be used to select the wavelength set value and against direction switching push button 124D, when pressing along direction switching push button 124 or contrary direction switching push button 124D at every turn, be stored in wavelength set value Se (a), Se (b) in the wavelength set value storage part 122 ... in this order or the order opposite with said sequence selected.

Display mode switching part 134, connect normal image the Show Button 134T and diagnosis pictorial display button 134S, if press normal image the Show Button 134T, then switch to the normal image display mode from display mode, if press diagnosis with pictorial display button 134S, then switch to the diagnosis image display mode from display mode.

That is to say, if press normal image the Show Button 134T, broadband beam split view data Dr, Dg, Db that display mode switching part 134 can will be obtained by the shooting of image pickup part 119 are sent to general image data generating unit 142, general image data generating unit 142 synthetic above-mentioned broadband beam split view data Dr, Dg, the Db that are transmitted generate general image data Dt.And, imported the display device 80 of the above-mentioned general image data Dt that transmits by general image data generating unit 142, show normal image Gt.

On the other hand, if press diagnosis pictorial display button 134S, display mode switching part 134 is sent to above-mentioned broadband beam split view data Dr, Dg, Db spectroscopy scheme and looks like to infer in the operational part 128, spectroscopy scheme looks like to infer operational part 128, according to looking like to infer computing, generate arrowband beam split view data Db1, Db2, Db3 based on the broadband beam split view data Dr of above-mentioned transmission, the spectroscopy scheme of Dg, Db.And the diagnosis of having imported above-mentioned arrowband beam split view data Db1, Db2, Db3 can be synthesized it, generate the diagnosis view data Ds of the diagnosis of expression organism mucosa 1 with image with view data generating unit 144., imported display device 80 that the diagnosis of by diagnosis with view data generating unit 144 being exported use view data Ds, shown diagnosis image Gs thereafter.

Above-mentioned up-to-date wavelength set value storage part 136, even the driving power that contains at electronic endoscope apparatus 100 is under the situation of OFF state, can carry out the stand-by power supply 137 of the standby mechanism of conduct that the storage of the wavelength set value in this up-to-date wavelength set value storage part 136 keeps.

Below, describe at the effect of above-mentioned electronic endoscope apparatus.

From the white light Lw that lighting source 113 sends, by light collecting lens 114, after by an end incident of the light guide 115 of light harvesting, from then on the other end of light guide 115 penetrates.The white light Lw that penetrates from the other end of above-mentioned light guide 115 is by illuminating lens 116 illumination organism mucosas 1.

Be subjected to the illumination of white light Lw, be responsible for utilizing the reflected light Lh of picture of this organism mucosa 1 of organism mucosa 1 reflection, the colour of the front of the sensitive surface by being configured in the solid-state image pickup parts that above-mentioned image pickup part 110 possessed is inlayed light filter 112, in the time of by beam split, be imaged on the above-mentioned sensitive surface by imaging optical system 111.

Image pickup part 110, shooting is obtained broadband beam split view data Dr, Dg, the Db of the various expression broadband spectroscopy schemes of red frequency range, green frequency range and the blue frequency bands of representing above-mentioned organism mucosa 1 as Gr, Gg, Gb by the picture of the imaging on the sensitive surface of above-mentioned beam split.

When pressing normal image the Show Button 134T, when becoming the normal image display mode, adopting the normal image Gt of above-mentioned broadband beam split view data Dr, Dg, Db generation, be presented in the display device 80.On the other hand, diagnose with pictorial display button 134S when pressing, become and diagnose when using image display mode, utilization looks like to infer arrowband beam split view data Db1 that computing tries to achieve, Db2, Db3 based on the spectroscopy scheme of above-mentioned broadband beam split view data Dr, Dg, Db and the diagnosis image Gs that generates, is displayed in the display device 80.

Below, be described in detail at the switching of above-mentioned image display mode.

Diagnose with pictorial display button 134S when pressing, become and diagnose when using image display mode, if for example press along direction switching push button 124U, in the wavelength set value of a plurality of kinds of wavelength set value selection portion 124 from be stored in wavelength set value storage part 122, select wavelength set value Se (c) as the next wavelength set value of present selecteed wavelength set value Se (b).

And, represent that the data of wavelength set value Se (c) of λ c1, λ c2, the λ c3 of the frequency range of a plurality of kinds are imported in the matrix data extraction unit 132.

As shown in figure 10, as the wavelength set value, for example store the order by 400 (centre wavelengths), 500,600[λ 1, λ 2, λ 3: unit is nm] the wavelength set value (a) of standard (substantially) usefulness formed, be used to describe the wavelength set value (c) that the blood vessel B2 of wavelength set value (b) that 470,500,670 blood vessel B1 of blood vessel uses and 475,510,685 uses; Be used to describe particular organization 440,480,520 organize the wavelength set value (e) of organizing E2 use of E1 with wavelength set value (d) and 480,510,580; Be used to describe the wavelength set value (f) that 400,430,475 haemachrome of the difference of oxyhemoglobin and deoxy haemachrome is used; Be used to retouch out the wavelength set value (g) that blood-carotene of 415,450,500 of the difference of blood and carotene is used; Be used to retouch out blood and cytoplasmic difference 420,550, the wavelength set value (h) used of 600 blood-Cytoplasm etc., by wavelength set value selection portion 124, the wavelength set value that makes wherein expectation is by circulation selection in turn, and selecteed wavelength set value is input in the matrix data extraction unit 132.

Matrix data efferent 132, above-mentioned wavelength set value Se (c) with reference to input, to infer matrix data M (c) by the branch luminous reflectance that computing is used for inferring the beam split reflex strength of above-mentioned wavelength set value Se (c) represented each frequency range λ c1, λ c2, λ c3, from matrix data storage part 126, extract, again with this minute luminous reflectance infer matrix data M (c) and output to spectroscopy scheme and look like to infer in the operational part 128.

Spectroscopy scheme looks like to infer operational part 128, the branch luminous reflectance of above-mentioned matrix data extraction unit 132 inputs is inferred matrix data M (c) and passed through broadband beam split view data Dr, Dg, the Db that display mode switching part 134 is imported, look like to infer computing by adopting as shown in the formula the spectroscopy scheme shown in (1), obtain representing arrowband beam split view data Dc1, Dc2, the Dc3 of the arrowband spectroscopy scheme of the organism mucosa 1 among above-mentioned frequency range λ c1, λ c2, the λ c3 as Gc1, Gc2, Gc3 as matrix operations.

Be stored in branch luminous reflectance in the matrix data storage part 126 and infer an example of matrix data, can exemplify the data of above-mentioned table 1.

And, look like to infer in the operational part 128 at above-mentioned spectroscopy scheme, according to above-mentioned coefficient k _Pr, k _Pg, k _PbBroadband beam split view data Dr, Dg, Db with from image pickup part 110 outputs carry out the matrix operations of following formula 3.Also have, by above-mentioned coefficient k _Pr, k _Pg, k _PbThe matrix of 3 row * 3 row that constitute is that the corresponding luminous reflectance that divides is inferred matrix data.In addition, the R in the formula, G, B are corresponding above-mentioned broadband beam split view data Dr, Dg, Db.

[formula 3]

$\left[\begin{array}{c}\mathrm{\λ}1\\ \mathrm{\λ}2\\ \mathrm{\λ}3\end{array}\right]=\left[\begin{array}{ccc}k1r& k1g& k1b\\ k2r& k2g& k2b\\ k3r& k3g& k3b\end{array}\right]\×\left[\begin{array}{c}R\\ G\\ B\end{array}\right]$

That is to say, as λ 1, λ 2, λ 3, for example when the parameter p 21 (centre wavelength 500nm) of option table 1, p45 (centre wavelength 620nm), p51 (centre wavelength 650nm), as coefficient (k _Pr, k _Pg, k _Pb), can be with (0.00119,0.002346,0.0016) of p21, (0.004022,0.000068 ,-0.00097), (0.005152 ,-0.00192,0.000088) substitution following formula of p51 of p45.

[0044B]

In above-mentioned formula 3, the state of having imported above-mentioned each parameter value is as follows.

[formula 4]

$\left[\begin{array}{c}\mathrm{\λ}1\\ \mathrm{\λ}2\\ \mathrm{\λ}3\end{array}\right]=\left[\begin{array}{ccc}-0.00119& 0.002346& 0.0016\\ 0.004022& 0.000068& -0.00097\\ 0.005152& -0.00192& 0.000088\end{array}\right]\×\left[\begin{array}{c}R\\ G\\ B\end{array}\right]$

Synthesized that computing is inferred in beam split like this and the diagnosis image of the arrowband spectroscopy scheme picture of trying to achieve, utilized the colour content of Fig. 4 and frequency range shown in Figure 5 to constitute.That is to say that Fig. 4 is on the spectral sensitivity characteristic of being made up of the light filter of former colour pattern of inlaying light filter, overlap to form the concept map (scale of the sensitivity of each frequency range of light filter and λ 1, λ 2, λ 3 inconsistent) of diagnosis with 3 frequency ranges of image.In addition, Fig. 5 is in the distribution of the beam split reflex strength of organism mucosa, overlaps to form the concept map of above-mentioned diagnosis with 3 frequency ranges of image.As above-mentioned λ 1, λ 2, λ 3, selecteed parameter p 21, p45, p51, such as shown, expression is a centre wavelength with 500nm, 620nm, 650nm in turn, the frequency range of the scope about ± 10nm.Above-mentioned diagnosis image, the color of 3 kinds of frequency ranges constitutes thus.

That is to say, corresponding above-mentioned spectroscopy scheme looks like to infer λ 1, λ 2, the arrowband beam split view data Dc1 of λ 3, Dc2, the Dc3 of the above-mentioned formula that computing obtains, being imported into diagnosis is displayed in the display device 80 with image Gs (c) with the represented diagnosis of view data Ds (c) with view data Ds (c), diagnosis thereafter with synthetic in the view data generating unit 144, generation diagnosis.

Also have, when whenever pressing above-mentioned suitable direction switching push button 124U or contrary direction switching push button 124D, repeatedly generate the above-mentioned action of the diagnosis of corresponding selecteed wavelength set value with image, mutual different types of diagnosis is shown in turn with image.

On the other hand, by display mode switching part 134 is switched to the normal image display mode, can show common coloured image.

Also have, utilize above-mentioned spectroscopy scheme to look like the maneuver of inferring computing, obtaining arrowband spectroscopy scheme picture, can open 2003-93336 communique or three residences ocean, one work [assay of digital color image] Tokyo University publishing house etc. with reference to the spy.

Below, at by display mode switching part 134, from the normal image display mode when diagnosis is switched with image display mode, the diagnosis of the wavelength set value of corresponding stored in up-to-date wavelength set value storage part 136 is described with the effect that pictorial display comes out.

For example, use in the image display mode in diagnosis, if when selecting wavelength set value Se (g) by wavelength set value selection portion 124, the data that show wavelength setting value Se (g) are forwarded to the matrix data extraction unit 132 from wavelength set value selection portion 124, this moment also can be in up-to-date wavelength set value storage part 136 data of storage representation this wavelength set value Se (g).And, as above-mentioned, adopt the branch luminous reflectance of corresponding wavelength setting value Se (g) to infer the diagnosis image Gs (g) that matrix data M (g) generates, be displayed in the display device.

When press normal image the Show Button 134T, from diagnosis use image display mode when normal image display mode switch, become following state thereafter.Promptly the state that is displayed on the display device 80 with image Gs (g) from diagnosis switches to the state that normal image Gt is shown, but up-to-date wavelength set value storage part 136 still keeps it to store the state of above-mentioned wavelength set value Se (g).

Secondly, if press diagnosis with pictorial display button 134S, when switching to diagnosis and use image display mode, the in the initial stage of that display setting portion 138 detected from above-mentioned normal image pattern and switched to the situation of using image display mode of diagnosing.And, this at initial stage display setting portion 138, wavelength set value Se (g) with reference to being stored in the up-to-date wavelength set value storage part 136 becomes the such mode of state of having selected wavelength set value Se (g) with wavelength set value selection portion 124, controls above-mentioned wavelength set value selection portion 124.

Thus, with above-mentioned identical, the diagnosis that the branch luminous reflectance that utilizes corresponding wavelength to set value Se (g) is inferred matrix data M (g) generation is revealed with image Gs (g).

That is to say, when from normal image when diagnosis shows with image switching, matrix data extraction unit 132 is extracted the branch luminous reflectance of the corresponding wavelength setting value Se (g) that is stored in the up-to-date wavelength set value storage part 136 and is inferred matrix data M (g), the branch luminous reflectance of this extraction is inferred matrix data M (g) output to spectroscopy scheme and look like to infer in the operational part 128.And, with above-mentioned identical, implement spectroscopy scheme and look like to infer computing etc., diagnosis is displayed in the display device 80 with image Gs (g).

After above-mentioned diagnosis showed with image Gs (g), the diagnosis that can make correspondence press the expectation of the wavelength set value of selecting along direction switching push button 124U or contrary direction switching push button 124D was come out with pictorial display.

In the above-described embodiment, as the mechanism of selecting the wavelength set value be adopt along direction and contrary direction circulate in turn select Se (a), Se (b) ... Se (h) circulation switching mode, but be not limited to the sort of situation.

For example, selection does not as described above circulate, only along direction and backward select in turn wavelength set value Se (a), Se (b) ... under the situation of Se (h), promptly adopt in wavelength set value Se (h) back and select wavelength set value Se (a), behind wavelength set value Se (a), do not select the restriction order switching mode of wavelength set value Se (h).Also have, also can adopt possess can select at random each wavelength Se (a), Se (b) ... the switching mode at random of each button of Se (h) etc.

Adopt above-mentioned restriction order switching mode, the situation of switching mode at random, effect when adopting above-mentioned circulation switching mode is identical, promptly from normal image to diagnosis when using image switching, corresponding stored is come out with pictorial display in the diagnosis of the wavelength set value of up-to-date wavelength set value storing mechanism, obtain to carry out easilier the effect of the diagnosis of normal image and expectation with the handover operation of image.

Also have, when the selecteed up-to-date wavelength set value of storage, from normal image to diagnosis during with the demonstration of image switching image, show the formation of the diagnosis of corresponding above-mentioned up-to-date wavelength set value with image, which kind of mode all can adopt, be not limited to adopt above-mentioned up-to-date wavelength set value storage part and the initial stage display setting portion situation.

When the above-mentioned selecteed up-to-date wavelength set value of storage, from normal image to diagnosis during with the demonstration of image switching image, show the mode of the diagnosis of corresponding above-mentioned up-to-date wavelength set value as realizing, can adopt the mode shown in the following variation etc. with the function of image.

(variation 1)

Fig. 1 is the block diagram that the summary of expression variation 1 constitutes, and is the part of change Fig. 9, the figure that amplification shows its part.

This variation 1 omit above-mentioned up-to-date wavelength set value storage part 136 shown in Figure 9 and the initial stage display setting portion 138, use in the image display mode in diagnosis, under pressing, possess by the wavelength set value of the change of the selection mode of forbidding the wavelength set value and select the 124 ' mode that replaces above-mentioned wavelength set value selection portion 124 along the situation beyond direction switching push button 124U or the contrary direction switching push button 124D.Like this, available this wavelength set value selection portion 124 ' realizes and display setting portion 138 the identical effect of situation of the initial stage of employing.

That is to say, wavelength set value selection portion 124 ', detect expression and switch signal down with image display mode to the normal image display mode from display mode switching part 134 from diagnosis, the selection by maintenance the state of up-to-date wavelength set value, store above-mentioned up-to-date wavelength set value.And, when demonstration from normal image to diagnosis usefulness image switching image, by keeping above-mentioned up-to-date wavelength set to be worth selecteed state, initial value as selecteed wavelength set value, select above-mentioned up-to-date wavelength set value, the diagnosis of its corresponding above-mentioned up-to-date wavelength set value is come out with pictorial display.Also have, above-mentioned wavelength set value selection portion 124 ', detect expression from diagnosis with the signal from display mode switching part 134 of image display mode under the normal image display mode switches, eliminate the forbidding of change of the selection mode of above-mentioned wavelength set value.

In these cases, wavelength set value selection portion 124 ' have concurrently utilize up-to-date wavelength set value storage part 136 that Fig. 9 illustrates and the initial stage display setting portion 138.Other formation and effect thereof are identical with the situation of utilizing Fig. 9 to illustrate.

Also have, above-mentioned wavelength set value selection portion 124 ', the driving power that also can contain at electronic endoscope apparatus 100 is under the situation of OFF state, can keep the stand-by power supply 125 of the standby mechanism of conduct of the storage of up-to-date wavelength set value.

(variation 2)

Figure 12 is the figure that the summary of expression variation 2 constitutes, and is the part of change Fig. 9, the figure that amplification shows its part.

This variation 2 omit above-mentioned up-to-date wavelength set value storage parts 136 shown in Figure 9 and the initial stage display setting portion 138, possess storage part 146 and transmit control part 148.

Above-mentioned storage part 146, storage is sent to the up-to-date branch luminous reflectance that spectroscopy scheme looks like to infer operational part 128 from matrix data extraction unit 132 and infers matrix data M.In addition, above-mentioned transmission control part 148, when from the normal image pattern when diagnosis is switched with image model, detect this switching, the branch luminous reflectance that blocking-up matrix data extraction unit 132 looks like to infer operational part 128 to spectroscopy scheme is inferred the transmission of matrix data, and the up-to-date branch luminous reflectance that storage part 146 will be stored is inferred matrix data M and is sent to spectroscopy scheme from storage part 146 and looks like to infer the operational part 128.

On the other hand, use in the image model in diagnosis, when if control part 148 detects and is pressed along direction switching push button 124U or contrary direction switching push button 124D, detect the transmission control part 148 of this switching, remove from the matrix data extraction unit 132 of blocking-up and look like to infer the transmission that the branch luminous reflectance of operational part 128 is inferred matrix data M to spectroscopy scheme.

Owing to possess above-mentioned storage part 146 and transmit control part 148, identical with above-mentioned variation 1, when the selecteed up-to-date wavelength set value of storage, when diagnosis is carried out the switching of demonstration of image with image, the diagnosis of its corresponding above-mentioned up-to-date wavelength set value is come out from normal image with pictorial display.

Above-mentioned storage part 146 is that storage divides luminous reflectance to infer matrix data, but this minute luminous reflectance to infer matrix data be corresponding wavelength setting value, storage part 146 can be regarded as storage up-to-date wavelength set value in fact, the formation of this variation 2 comprises in the present invention.

Claims (12)

1, a kind of endoscope apparatus utilizes the picture pick-up device that is loaded in the endoscope to form the colour picture signal of observed body, and it is provided with:

Storage part, its storage constitutes the matrix data of the frequency range of spectroscopy scheme picture;

The spectroscopy scheme picture forms circuit, and it utilizes the matrix data of above-mentioned storage part, carries out the matrix operations based on above-mentioned colour picture signal, forms the spectroscopy scheme picture of the frequency range of selecteed arbitrary value;

Wavelength selection mechanism, its limit continuously or stage ground switch the frequency range that forms the formed spectroscopy scheme picture of circuit by above-mentioned spectroscopy scheme picture, the frequency range of limit selection arbitrary value.

2, endoscope apparatus according to claim 1 is characterized in that,

Be provided with wavelength and switch the amplitude set mechanism, it is used for the switching amplitude of variable setting by the frequency range of above-mentioned wavelength selection mechanism selection.

3, a kind of endoscope apparatus utilizes the picture pick-up device that is loaded in the endoscope, the colour picture signal that forms observed body, is provided with:

Storage part, its storage constitutes the matrix data of the frequency range of spectroscopy scheme picture;

The spectroscopy scheme picture forms circuit, and it utilizes the matrix data of above-mentioned storage part, carries out the matrix operations based on above-mentioned colour picture signal, forms the spectroscopy scheme picture of the frequency range of selecteed arbitrary value;

Wavelength selection mechanism, it is set a plurality of frequency ranges that above-mentioned spectroscopy scheme picture forms the formed spectroscopy scheme picture of circuit as a plurality of wavelength set values, and the frequency range that arbitrary value is selected on above-mentioned wavelength set value limit is switched on the limit.

4, endoscope apparatus according to claim 3 is characterized in that,

Above-mentioned wavelength selection mechanism, can with under monochromatic mode, form spectroscopy scheme as the time single frequency band, be chosen as above-mentioned wavelength set value.

5, according to claim 3 or 4 described endoscope apparatus, it is characterized in that,

Can be by the wavelength set value of above-mentioned wavelength selection mechanism selection, the wavelength set value or be used to that comprises the wavelength set value of the difference that is used to describe oxyhemoglobin and deoxy haemachrome and be used to describe the difference of blood and carotene is described the wavelength set value of the difference of blood and Cytoplasm.

6, endoscope apparatus according to claim 1 is characterized in that,

Also possesses the wavelength storing mechanism of storing in advance by the selected above-mentioned frequency range of above-mentioned wavelength selection mechanism.

7, endoscope apparatus according to claim 3 is characterized in that,

Also possess the wavelength storing mechanism, it is stored in advance as a plurality of frequency ranges by the selected above-mentioned wavelength set value of above-mentioned wavelength selection mechanism.

8, according to claim 6 or 7 described endoscope apparatus, it is characterized in that,

Above-mentioned wavelength storing mechanism except that the zone of storing above-mentioned frequency range in advance, also possesses the default data memory area of the initial set value that is stored in selecteed frequency range in the wavelength selection mechanism.

9, according to claim 6 or 7 described endoscope apparatus, it is characterized in that,

Above-mentioned wavelength storing mechanism except that the zone of storing above-mentioned frequency range in advance, also possesses storage in advance keeps reading the frequency range that is changed the back from above-mentioned zone change wavelength storage area.

10, endoscope apparatus according to claim 9 is characterized in that,

Have the frequency range that will be stored in the above-mentioned change wavelength storage area, be written to the formation in the zone of the above-mentioned frequency range of storage.

11, a kind of electronic endoscope apparatus, it is the described electronic endoscope apparatus of claim 3, can with the common image of organism mucosa and obtain based on the matrix operations of the wavelength set value of from above-mentioned a plurality of wavelength set values, selecting, as the diagnosis image of the arrowband spectroscopy scheme picture of above-mentioned organism mucosa, switch demonstration

It possesses the up-to-date wavelength set value storing mechanism of the selecteed up-to-date above-mentioned wavelength set value of storage,

When from above-mentioned common image when image switching is used in above-mentioned diagnosis, can show corresponding to the diagnosis image that is stored in the above-mentioned up-to-date wavelength set value in the above-mentioned up-to-date wavelength set value storing mechanism.

12, endoscope apparatus according to claim 11 is characterized in that,

Above-mentioned up-to-date wavelength set value storing mechanism, contain standby mechanism, even this standby mechanism is under the situation of OFF state at the driving power of above-mentioned electronic endoscope apparatus, the storage that can carry out the above-mentioned up-to-date wavelength set value of above-mentioned up-to-date wavelength set value storing mechanism keeps.

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