CN100418555C - Medicine for treating sub-health and endocrine disorders and preparation method thereof - Google Patents

Abstract

The present invention discloses a medicine for treating subhealth and endocrine disorder, which is prepared from astragalus root, lucid ganoderma mulberry fruit, donkey-hide gelatin, deerhorn glue desertliving cistanche, leech, peach kernel, barbary wolfberry fruit, tuckahoe, longspur epimedium and common macrocarpium fruit. The medicine has the functions of nourishing the liver, invigorating the kidney, activating blood circulation, removing blood stasis, benefiting qi, replenishing the blood and balancing yin and yang, and is suitable for people with subhealth and endocrine disturbance.

Description

Medicine for treating sub-health and endocrine disorders and preparation method thereof

Technical field:

The invention relates to a medicine for treating sub-health and endocrine disorders and a preparation method thereof, belonging to the technical field of traditional Chinese medicines.

Background technique:

With the development of society, the pace of work and life of modern people is accelerating, people are in a state of fierce competition, long-term psychological tension, repeated psychological stimulation and bad emotions, and changes in people's living environment and lifestyle have caused long-term depression. Mental fatigue leads to sub-health; and endocrine disorders are mostly caused by excessive stress and emotional tension. Such tension and emotional changes are reflected in the nervous system and cause hormone secretion disorders. This disease widely exists in all age groups. In my country, the incidence of sub-health is about 50% among middle-aged people, and as high as 70% among intellectuals and business managers (managers, chairman of the board).

Sub-health is a new concept proposed by the medical field in recent years. It refers to the clinical manifestations of insomnia, dreaminess, weakness of the waist and knees, anxiety, fatigue, dizziness, tinnitus, hot spontaneous sweating, dull complexion or chlorosis despite no obvious disease. , black eye circles, obesity, poor diet, and women's various pigmentation, constipation and other symptoms, but the doctor's examination is "no disease". Kidney deficiency".

Most of the drugs used to treat sub-health and endocrine disorders on the market are to improve sleep and treat neurological symptoms, and some will produce other symptoms, such as hyperlipidemia and irritability.

Contents of the invention

In order to allow people in a sub-healthy state to live and work better, the inventors, through repeated research, aiming at the pathological basis of sub-healthy etiology mainly due to lack of nourishment of mind and spirit, deficiency of both qi and blood, and loss of liver and spleen, from the balance of yin and yang, conditioning Starting from the viscera, the yin and yang, qi and blood, and viscera of the human body can be balanced; in view of endocrine disorders, which are manifestations of kidney deficiency and the pathological basis caused by stagnation of qi and blood, start with regulating endocrine, so that qi and blood can flow smoothly, so that essence and blood can nourish the whole body, Promote blood circulation. The drug has been developed to nourish the liver and kidney, promote blood circulation, remove blood stasis, replenish qi and blood, and balance yin and yang, and is suitable for sub-health and endocrine disorders.

The purpose of the invention is to disclose a traditional Chinese medicine component of medicine for treating sub-health and endocrine disorders.

Another object of the present invention is to disclose the preparation method of this medicine.

The medicine of the present invention selects 12 kinds of traditional Chinese medicines for combination, and is composed of astragalus, ganoderma lucidum, mulberry, donkey-hide gelatin, antler gum, cistanche, leech, peach kernel, medlar, poria cocos, epimedium and dogwood.

After continuous exploration, the applicant determined that the dosage range of each component in this medicine is as follows: astragalus 15g-120g, Ganoderma lucidum 10g-150g, mulberry 12g-100g, donkey-hide gelatin 5g-100g, antler gum 3g-70g, cistanche 15g-100g, leeches 5g-90g, peach kernel 10g-120g, poria cocos 8g-90g, medlar 12g-120g, epimedium 5g-60g, dogwood 15g-120g.

The preferred dosage range of each ingredient is: astragalus 25g-100g, Ganoderma lucidum 20g-120g, mulberry 30g-100g, donkey-hide gelatin 20g-90g, antler gum 20g-70g, cistanche 20g-100g, leech 15g-75g, peach kernel 30g-100g , Poria cocos 20g-80g, medlar 25g-90g, epimedium 20g-50g, dogwood 25g-100g.

The optimal dosage range of each ingredient is: astragalus 45g-65g, Ganoderma lucidum 60g-100g, mulberry 50g-90g, donkey-hide gelatin 40g-70g, antler gum 35g-60g, cistanche 60g-80g, leech 45g-70g, peach kernel 50g- 90g, Poria cocos 45g-65g, medlar 50g-70g, epimedium 30g-40g, dogwood 60g-70g.

The optimal dosage of each ingredient is: astragalus 60g, ganoderma lucidum 80g, mulberry 80g, donkey-hide gelatin 65g, antler gum 50g, cistanche 80g, leech 65g, peach kernel 80g, poria cocos 65g, medlar 70g, epimedium 40g, dogwood 70g.

The preparation process of the drug is as follows:

(1), pulverize the astragalus, Ganoderma lucidum, mulberry, cistanche, leech, peach kernel, Poria cocos, wolfberry, epimedium, dogwood, and then sieve through a 180 mesh basket to collect the powder, and use cobalt-60 gamma ray Sterilized by irradiation;

(2) Add donkey-hide gelatin and antler gum to the powder collected in step 1, stir evenly, fill capsules, sterilize them with cobalt-60 gamma rays, and bottle them.

Wherein, curing in step (2) refers to glue-like medicinal materials such as donkey-hide gelatin, deer horn glue, etc., in order to avoid sticking to the pan, the medicine is generally boiled in a separate pot and then melted, and taken together with other medicinal liquids.

In 12 kinds of Chinese medicines selected for use of the present invention:

Astragalus is warm in nature and sweet in taste. It has the effects of invigorating qi and promoting yang, benefiting health and solidifying the surface, detoxifying and promoting muscle growth, diuresis and reducing swelling. The polysaccharide contained in it has the effect of increasing immunity, replenishing deficiencies, nourishing vitality, and strengthening the spleen and stomach , blood circulation;

Ganoderma lucidum is mild in nature and sweet in taste, and has the effects of nourishing blood and calming the nerves, invigorating the spleen and stomach, and the triterpenoids contained in it can not only enhance the activation of monocytes, macrophages, NK cells, nuclear T, and B lymphocytes It can also promote the synthesis and release of immune cytokines, thereby correcting immune dysfunction, enhancing immune function, nourishing the qi of the five internal organs, and calming the nerves;

Mulberry fruit is cold in nature and sweet in taste. It has the effects of nourishing yin and blood, promoting body fluid, and moisturizing the intestines. The fatty acid contained in it can enhance immunity and stimulate lymphocyte transformation. It is used for dizziness, dark eyes, tinnitus, insomnia, Premature graying of beard and hair, nourishing kidney and consolidating essence;

Donkey-hide gelatin is flat in nature and sweet in taste, and has the effects of nourishing blood, stopping bleeding, nourishing, and nourishing the lungs. It is used for blood deficiency, dizziness, palpitations, yin deficiency, upset, and insomnia;

Deer antler gum is warm in nature, sweet and salty in taste, has the effect of nourishing the liver and kidney, and benefiting essence and blood.

Cistanche deserticola is warm in nature, sweet and salty in taste, has the effect of invigorating the kidney and yang, moistening the intestines and laxative.

Leech is flat in nature, salty and bitter in taste, and has the effect of dispelling blood stasis and lowering blood fat;

Peach kernel is flat in nature, sweet and bitter in taste, has the effect of promoting blood circulation and removing blood stasis, smoothing intestines and laxative;

Lycium barbarum is flat in nature and sweet in taste, and has the effects of nourishing the liver and kidney, improving eyesight, and moistening the lungs. It contains betaine, polysaccharides, and riboflavin, which can enhance the immunity of cells and the body, promote hematopoiesis, and have anti-inflammatory effects. Aging and hypoglycemic effects, used for liver and kidney yin deficiency, dizziness, vision loss, weak waist and knees, can replenish essence;

Poria cocos is flat in nature, sweet and light in taste, and has the effects of calming the mind, calming the nerves, diuresis and expelling dampness, strengthening the spleen and stomach;

Epimedium is warm in nature, pungent and sweet in taste, and has the effects of invigorating the kidney and strengthening yang, dispelling wind and dehumidification. It contains total flavonoids and polysaccharides in Epimedium, which can expand peripheral blood vessels, improve microcirculation, and improve the immune function of the body. It is used for impotence , frequent urination, weak waist and knees, can benefit essence and strengthen muscles and bones;

Cornus officinalis is lukewarm in nature and sour in taste. It has the effects of nourishing the liver and kidney, astringent and astringent, and can replenish essence and yang, increase yin and calm the five internal organs.

The medicine of the invention has the effects of nourishing qi and blood, nourishing liver and kidney, promoting blood circulation and removing blood stasis, moistening intestines and laxative, balancing yin and yang, and improving body immunity. The king medicines are antler glue, cistanche, medlar, epimedium, and mulberry, which have the effects of nourishing the liver and kidney, and nourishing the essence and blood; astragalus, ganoderma lucidum, dogwood, and donkey-hide gelatin, which are beneficial to vitality and soothing the five internal organs, are the ministerial medicines; The leeches and peach kernels with the effect of promoting blood circulation and removing blood stasis are used as adjuvant drugs; Poria cocos is used as an adjuvant drug to promote water and dampness, invigorate the spleen and stomach, calm the mind and calm the nerves, and regulate water passages to form the medicine of the present invention. Fundamentally balance the body's yin and yang, qi and blood, and viscera, make qi and blood unobstructed, nourish the whole body with essence and blood, promote blood circulation, and effectively treat sub-health and endocrine disorders.

Detailed ways

The beneficial effects that the medicine of the present invention (hereinafter referred to as "Ya Kang Bao") has are illustrated by the test example below, and this test example is a clinical efficacy test of the medicine of the present invention

[Test example]

1. General information

1,000 patients with sub-health and endocrine symptoms were admitted and treated.

2. Diagnostic criteria

Sub-health symptoms: memory loss, insomnia, dreaminess, mental fatigue and other mental disorders;

Endocrine disorders: Chloasma and freckles appear on women's faces.

3. Treatment method

Oral, three times a day, three to five capsules at a time or as directed by the doctor, take it on an empty flight, one month is a course of treatment.

4. Evaluating Criteria for Efficacy

Sub-health symptoms: the elimination of various sub-health symptoms is a cure;

Endocrine disorders: the cure is to eliminate all kinds of spots in women.

5. Treatment results

1,000 patients took Yacombo for three courses of treatment, and the treatment results are as follows:

For sub-healthy patients, the effective rate is 100%, and the cure rate is 100%;

For women's various stains, the effective rate is 100%, and the cure rate is 96.4%.

The following examples illustrate the preparation of the medicament of the present invention.

[Example]

(1) Weigh 60g astragalus, 80g ganoderma lucidum, 80g mulberry, 65g donkey-hide gelatin, 50g antler gum, 80g cistanche, 65g leech, 80g peach kernel, 70g medlar, 65g Yunling, 40g epimedium, 70g dogwood;

(2), pulverize 10 kinds of medicinal materials except donkey-hide gelatin and deer horn glue in step (1), screen with a 180-order basket, collect medicinal powder, and carry out irradiation sterilization with cobalt-60 gamma rays;

(3) Add donkey-hide gelatin and antler gum to the medicinal powder in step (2), stir thoroughly, fill capsules, and irradiate and sterilize with cobalt-60 gamma rays for bottling.

Claims (5)

1. medicine for the treatment of subhealth state and endocrine disturbance is characterized in that it is made up of following materials of weight proportions medicine: Radix Astragali 15g-120g, Ganoderma lucidum seu Japonicum 10g-150g, Fructus Mori 12g-100g, Colla Corii Asini 5g-100g, Colla cornus cervi 3g-70g, Herba Cistanches 15g-100g, Hirudo 5g-90g, Semen Persicae 10g-120g, Poria 8g-90g, Fructus Lycii 12g-120g, Herba Epimedii 5g-60g, Fructus Corni 15g-120g.

2. a kind of medicine for the treatment of subhealth state and endocrine disturbance according to claim 1, wherein the weight proportion of each crude drug is: Radix Astragali 25g-100g, Ganoderma lucidum seu Japonicum 20g-120g, Fructus Mori 30g-100g, Colla Corii Asini 20g-90g, Colla cornus cervi 20g-70g, Herba Cistanches 20g-100g, Hirudo 15g-75g, Semen Persicae 30g-100g, Poria 20g-80g, Fructus Lycii 25g-90g, Herba Epimedii 20g-50g, Fructus Corni 25g-100g.

3. a kind of medicine for the treatment of subhealth state and endocrine disturbance according to claim 1, wherein the weight proportion of each crude drug is: Radix Astragali 45g-65g, Ganoderma lucidum seu Japonicum 60g-100g, Fructus Mori 50g-90g, Colla Corii Asini 40g-70g, Colla cornus cervi 35g-60g, Herba Cistanches 60g-80g, Hirudo 45g-70g, Semen Persicae 50g-90g, Poria 45g-65g, Fructus Lycii 50g-70g, Herba Epimedii 30g-40g, Fructus Corni 60g-70g.

4. a kind of medicine for the treatment of subhealth state and endocrine disturbance according to claim 1, wherein the weight proportion of each crude drug is: Radix Astragali 60g, Ganoderma lucidum seu Japonicum 80g, Fructus Mori 80g, Colla Corii Asini 65g, Colla cornus cervi 50g, Herba Cistanches 80g, Hirudo 65g, Semen Persicae 80g, Poria 65g, Fructus Lycii 70g, Herba Epimedii 40g, Fructus Corni 70g.

5. the described a kind of preparation method for the treatment of subhealth state and endocrine disturbance's medicine of claim 1, it is made up of following steps:

(1), with the described Radix Astragali, Ganoderma lucidum seu Japonicum, Fructus Mori, Herba Cistanches, Hirudo, Semen Persicae, Poria, Fructus Lycii, Herba Epimedii, Fructus Corni, pulverize, through the screening of 180 order square-bottomed bamboo baskets, collect medicated powder then, carry out irradiation sterilization with cobalt-60 gamma ray;

(2), stir evenly, fill capsule, carry out irradiation sterilization, bottle with cobalt-60 gamma ray with adding after Colla Corii Asini, the Colla cornus cervi molten in the medicated powder of collecting in the step 1.