CN100415097C - Synergistic Pesticide Mixtures for Animal Pest Control - Google Patents

Abstract

The present invention relates to synergistic mixtures comprising one or more sodium channel effectors and the compound (Z) -3- (6-chloro-3-picolyl) -1, 3-thiazolidin-2-ylidenecyanamide or the compound (E) -1- (2-chloro-1, 3-thiazol-5-ylmethyl) -3-methyl-2-nitroguanidine or the compound 1- [ (6-chloro-3-pyridyl) methyl ] -N-nitro-2-imidazolidinimine and the use of these mixtures for controlling pests.

Description

Synergistic Pesticide Mixtures for Animal Pest Control

This application is a divisional application of the application No. 02803928.9. The filing date of the application No. 02803928.9 is January 7, 2002. The applicant is Bayer Crop Science AG.

The present invention relates to synergistic mixtures comprising one or more sodium ion channel effectors and the compound (Z)-3-(6-chloro-3-pyridylmethyl)-1,3-thiazolidin-2-ylidene Cyanamide or compound (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine or compound 1-[(6-chloro-3- Pyridyl)methyl]-N-nitro-2-imidazolidine imines and the use of these mixtures for controlling pests.

Mixtures of sodium ion channel antagonists with certain compounds selected from modulators of acetylcholine receptors are known (WO 00/54591, Research Disclosure May 1997, No. 39786). In practice, however, the above-mentioned known mixtures are not always satisfactory, either because of the poor insecticidal effect against certain insects or because the required application rates are very high.

It has now been found that one or more sodium ion channel effectors and compounds (Z)-3-(6-chloro-3-pyridylmethyl)-1,3-thiazolidine-2-ylidene cyanamide (clothiazolin (Thiacloprid)) or compound (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine (Chlothianidin) or compound 1-[( Mixtures of 6-chloro-3-pyridyl)methyl]-N-nitro-2-imidazolidineimine (imidacloprid) have synergistic activity and are suitable for controlling pests. Due to the aforementioned synergistic effect, it is possible to significantly reduce the amount of active compound used, ie the activity of the mixture is greater than that of the individual components.

The term sodium channel effector refers to compounds that prevent the transport of sodium ions across the cell membrane of nerve cells. The aforementioned compounds and their modes of action have been disclosed, for example, in "Pesticide Biochemistry and Physiology, 60:177-185" and "Archives of Insect Biochemistry and Physiology, 37:91-103". Sodium channel inhibitors have been disclosed, for example, in US Patents US 5,543,573; US 5,708,170; US 5,324,837 and US 5,462,938. As an example, compounds of the following formulas are listed:

in

A stands for CR ⁴ R ⁵ or NR ⁶ ,

W stands for O or S,

X, Y, Z, X', Y' and Z' each independently represent H, halogen, OH, CN, NO ₂ ,

stands for C ₁ -C ₆ -alkyl optionally substituted by one or more of the following groups: halogen, C ₁ -C ₃ -alkoxy, C ₁ -C ₃ -halogenated alkoxy, C ₃ -C ₆ -cyclo Alkyl, C ₂ -C ₆ -alkenyloxy or sulfonyloxy,

represents C ₁ -C ₆ -alkoxy optionally substituted by one or more of: halogen, C ₁ -C ₃ -alkoxy or C ₃ -C ₆ -cycloalkyl,

stands for C ₁ -C ₆ -alkoxycarbonyl, stands for C ₃ -C ₆ -cycloalkylcarbonyloxy, stands for phenyl optionally substituted by one or more of the following groups: halogen, C ₁ -C ₄ -alk radical or C ₁ -C ₄ -alkoxy,

represents aminocarbonyloxy optionally mono- or disubstituted by C ₁ -C ₃ -alkyl,

stands for C ₁ -C ₆ -alkoxycarbonyloxy, stands for C ₁ -C ₆ -alkylsulfonyloxy, stands for C ₂ -C ₆ -alkenyl or stands for NR ₁₂ R ₁₃ ,

m, p and q each independently represent 1, 2, 3, 4 or 5,

n stands for 0, 1 or 2,

r stands for 1 or 2,

t stands for 1, 2, 3 or 4,

R, R ¹ , R ² , R ³ , R ⁴ and R ⁵ each independently represent H or C ₁ -C ₄ -alkyl,

R ⁶ represents H, C ₁ -C ₆ -alkyl, C ₁ -C ₆ -haloalkyl, C ₁ -C ₆ -alkoxyalkyl, C ₁ -C ₆ -alkoxy, C ₁ -C ₆ -Haloalkoxy, C ₂ -C ₆ -alkenyl, C ₂ -C ₆ -alkynyl, C ₁ -C ₆ -alkylcarbonyl, C ₁ -C ₆ -alkoxycarbonyl, C ₁ -C ₆ - Alkylthio or C ₁ -C ₆ -haloalkylthio,

R ⁷ and R ⁸ each independently represent H, halogen, C ₁ -C ₆ -alkyl, C ₁ -C ₆ -alkylcarbonyloxy or represent phenyl optionally substituted by one or more of the following groups: halogen , CN, NO ₂ , C ₁ -C ₆ -alkyl, C ₁ -C ₆ -haloalkyl, C ₁ -C ₆ -alkoxy or C ₁ -C ₆ -haloalkoxy,

R ⁹ and R ¹⁰ each independently represent H or C ₁ -C ₄ -alkyl,

R ¹¹ represents H, C ₁ -C ₆ -alkyl, C ₁ -C ₆ -haloalkyl, C ₁ -C ₄ -alkylcarbonyl, C ₁ -C ₆ -alkoxycarbonyl or C ₁ -C ₆ - Haloalkoxycarbonyl,

R ¹² and R ¹³ each independently represent H or C ₁ -C ₆ -alkyl,

G stands for H,

represents C ₁ -C ₆ -alkyl optionally substituted by one or more of the following groups: halogen, C ₁ -C ₄ -alkoxy, C ₁ -C ₆ -haloalkoxy, CN, NO ₂ , S( O) _n R ¹⁴ , COR ¹⁵ , CO ₂ R ¹⁶ , phenyl or C ₃ -C ₆ -cycloalkyl,

stands for C ₁ -C ₆ -alkoxy, C ₁ -C ₆ -halogenated alkoxy, CN, NO ₂ ,

S(O) _n R ¹⁷ , COR ¹⁸ , CO ₂ R ¹⁹ ,

represents phenyl optionally substituted by one or more of the following groups: halogen, CN, C ₁ -C ₃ -haloalkyl or C ₁ -C ₃ -haloalkoxy,

represents C ₃ -C ₆ -cycloalkyl or phenylthio,

Q represents phenyl optionally substituted by one or more of the following groups: halogen, CN, SCN, NO ₂ , S(O) _n R ²⁰ , C ₁ -C ₄ -alkyl, C ₁ -C ₄ -haloalkyl , C ₁ -C ₄ -alkoxyalkyl, C ₁ -C ₆ -alkoxy, C ₁ -C ₆ -halogenated alkoxy or NR ²¹ R ²² ,

n stands for 0, 1 or 2,

R ¹⁴ , R ¹⁵ , R ¹⁶ , R ¹⁸ , R ¹⁹ , R ²¹ and R ²² each independently represent H or C ₁ -C ₆ -alkyl,

R ¹⁷ and R ²⁰ each independently represent C ₁ -C ₆ -alkyl or C ₁ -C ₆ -haloalkyl,

R ³³ represents CO ₂ R ³⁴ ,

R ³⁴ represents H, C ₁ -C ₆ -alkyl, C ₁ -C ₆ -haloalkyl, phenyl or halophenyl and the group

C=N stands for C-N or, in particular, stands for C=N.

Preference is given to sodium ion channel effectors of formula (I), especially those compounds in which C=N represents C=N.

Preference is also given to sodium ion channel effectors of formula (II), especially those compounds in which C=N represents C=N.

Preference is also given to sodium ion channel effectors of formula (III), especially those compounds in which C=N represents C=N.

Preferred compounds of formula (I), wherein

X _m represents 4-OCF ₃ or 4-SCF ₃ ,

Y _p represents 3-Cl, 3-CF ₃ , 3-CN, 4-Cl, 4-CF ₃ or 4-CN and

Z _q represents 3-Cl, 3-CF ₃ , 3-CN, 4-Cl, 4-CF ₃ or 4-CN.

Compounds of the formula may be mentioned

Preference is given to compounds of the formula (II) in which

_Y'p represents 4-OCF ₃ or 4-SCF ₃ ,

X' _m represents 3-Cl, 3-CF ₃ , 3-CN, 4-Cl, 4-CF ₃ or 4-CN,

R ⁷ stands for H and

R ⁸ represents phenyl substituted by 3-Cl, 3-CF ₃ , 3-CN, 4-Cl, 4-CF ₃ or 4-CN.

Compounds of formula that may be mentioned

Preference is given to compounds of formula (III) in which

Cl represents phenyl substituted by 4-OCF ₃ or 4-SCF ₃ ,

G stands for H, CO ₂ CH ₃ or CO ₂ C ₂ H ₅ ,

R ³³ represents CO ₂ CH ₃ or CO ₂ C ₂ H ₅ and

_Z't represents 3-Cl, 3-CF ₃ , 3-CN, 4-Cl, 4-CF ₃ or 4-CN.

Compounds of formula that may be mentioned

Oxadiazole

Other sodium channel inhibitors are also disclosed in US 5,116,850 and US 5,304,573. As an example, compounds represented by the following structural formulas are listed

in

W stands for oxygen or sulfur,

X" and Y" independently represent H, CN, SCN,

stands for C ₁ -C ₆ -alkyl optionally substituted by one or more of the following groups: halogen, NO ₂ , CN, C ₁ -C ₄ -alkoxy, C ₁ -C ₄ -alkylthio, phenyl , halophenyl, C ₁ -C ₄ -alkylsulfonyl or C ₁ -C ₄ -alkoxycarbonyl,

stands for C ₂ -C ₄ -alkenyl, C ₂ -C ₄ -halogenated alkenyl, C ₂ -C ₄ -alkynyl, C ₂ -C ₄ -halogenated alkynyl, C ₃ -C ₆ -cycloalkyl , C ₃ -C ₆ -halocycloalkyl,

represents phenyl optionally substituted by one or more of the following groups: halogen, CN, NO ₂ , C ₁ -C ₄ -alkyl, C ₁ -C ₄ -haloalkyl, C ₁ -C ₄ -alkoxy, C ₁ -C ₄ -haloalkoxy, C ₁ -C ₄ -alkylthio, C ₁ -C ₄ -alkylsulfonyl or C ₁ -C ₄ -halogenated alkylsulfonyl,

represents a six-membered aromatic ring containing one or two heteroatoms selected from the group consisting of 0 or 1 oxygen atom, 0 or 1 sulfur atom and 0, 1 or 2 nitrogen atoms and wherein the heteroaromatic ring is attached via a carbon atom and it is optionally substituted by one or more of the groups mentioned in X",

Q' stands for H,

represents C ₁ -C ₆ -alkyl optionally substituted by one or more of the following groups: halogen, CN, C ₁ -C ₃ -alkoxy, C ₁ -C ₆ -alkoxycarbonyl or phenyl, where Phenyl itself may also be substituted by one or more of the following groups: halogen, CN, NO ₂ , C ₁ -C ₄ -alkyl, C ₁ -C ₄ -haloalkyl, C ₁ -C ₄ -alkylsulfonyl and C ₁ -C ₄ -Alkylsulfinyl,

represents C ₂ -C ₆ -alkenyl, C ₂ -C ₆ -alkynyl or

represents C ₁ -C ₄ -alkylcarbonyl, C ₁ -C ₄ -halogenated alkylcarbonyl or represents NR ²⁸ R ²⁹ ,

or

represents a five or six membered heteroaromatic ring (e.g. pyridyl) containing one or two heteroatoms selected from 0 or 1 oxygen atom, 0 or 1 sulfur atom and 0, 1 or 2 nitrogen A group of heteroatoms consisting of atoms and wherein the heteroaromatic ring is connected via a carbon atom and optionally substituted by one or more of the groups mentioned in X",

m stands for 0, 1, 2, 3, 4 or 5,

G' represents phenyl optionally substituted one or more times by the radicals mentioned in X",

represents a five or six membered heteroaromatic ring (e.g. pyridyl) containing one or two heteroatoms selected from 0 or 1 oxygen atom, 0 or 1 sulfur atom and 0, 1 or 2 nitrogen A group of heteroatoms consisting of atoms and the heteroaryl ring is connected via a carbon atom and it is optionally substituted by one or more of the groups mentioned in X",

R ²³ , R ²⁴ , R ²⁵ , R ²⁶ , R ²⁷ , R ²⁸ and R ²⁹ each independently represent H or C ₁ -C ₄ -alkyl and groups,

C=N stands for C-N or, in particular for C=N.

Preference is given to compounds of the following formula (IV), wherein

X” _m stands for 4-OCF ₃ or 4-SCF ₃ ,

G' represents phenyl substituted by the following groups: 3-Cl, 3-CF ₃ , 3-CN, 4-Cl, 4-CF ₃ or 4-CN and

Q' represents a heterocyclic ring substituted by Cl or CF ₃ , such as 4-Cl-2-pyridyl.

As examples, the following compounds may be mentioned:

Preference is given to compounds of the following formula (V), wherein

Y" _m represents 4-OCF ₃ or 4-SCF ₃ .

As examples, the following compounds may be mentioned:

Other sodium channel effectors are benzophenone-hydrazones, such as disclosed in EP-O-0 742 202, JP-1000 14 69, WO 96/33 168, WP-O-647 622, WO 97/11 050 and WO 97/38 973 in. They include benzophenone-hydrazones of formula (VI)

in

R ³⁸ represents H, C ₁ -C ₆ -alkyl or C ₁ -C ₆ -alkoxycarbonyl, especially H or COCH ₃ ,

R ³¹ represents C ₁ -C ₆ -alkyl, especially methyl or ethyl,

R represents ^halogen , especially chlorine, and

R ³³ represents O-SO ₂ -C ₁ -C ₆ -alkyl or O-SO ₂ -C ₁ -C ₆ -haloalkyl, especially O-SO ₂ CH ₃ or O-SO ₂ -CF ₃ , or

represents CH ₂ -S(O) _y -C ₁ -C ₆ -alkyl or CH ₂ -S(O) _y -C ₁ -C ₆ -haloalkyl, wherein

y stands for 0, 1 or 2,

stands for especially (CH ₃ )S(O) _y CH ₃ , CH ₂ -S(O) _y C ₂ H ₅ or CH ₂ -S(O) _y CH ₂ CF ₃ , particularly preferably CH ₂ -S-CH ₃ .

Particular preference is given to the following compounds:

(Et = ethyl)

Another group of known sodium ion channel inhibitors are the bis-aryl-methylpiperidines, disclosed for example in WO 95/23 507, US 5,569,664, WO 96/36 228, WO 97/26 252, WO 98/00015 , WO 99/14 193 and WO 00/01 838. The above inhibitors include compounds of formula (VII)

in

R ³⁴ represents H or OH,

R ³⁵ and R ³⁶ each independently represent halogen, C ₁ -C ₆ -haloalkyl, haloalkylthio or C ₁ -C ₆ -haloalkoxy, especially CF ₃ , OCF ₃ and SCF ₃ ,

R ³⁷ represents H, C ₁ -C ₆ -alkyl, C ₁ -C ₆ -haloalkyl, C ₁ -C ₆ -alkoxy, C ₁ -C ₆ -halogenated alkoxy, C ₁ -C ₆ -alk Oxycarbonyl, NH-CO ₂ -C ₁ -C ₆ -alkyl or CH=NOC ₁ -C ₆ -alkyl,

A stands for CH or N and

B for N or

Particular preference is given to the following compounds:

Another group of sodium ion channel effectors are the oxadiazines, which are disclosed, for example, in WO 96/36618, WO 99/41 245, US 5,536,720 and WO 98/33 794.

They include compounds of formula (VIII)

in

R ³⁸ represents H, C ₁ -C ₆ -alkyl, C ₁ -C ₆ -alkylcarbonyl or C ₁ -C ₆ -alkylcarbonyloxy, especially H,

R ³⁹ represents C ₁ -C ₆ -alkyl or C ₁ -C ₆ -alkoxy,

R ⁴⁰ represents halogen, C ₁ -C ₆ -haloalkyl, C ₁ -C ₆ -haloalkoxy or C ₁ -C ₆ -haloalkylthio, especially chlorine, CF ₃ , OCF ₃ or SCF ₃ , and

Ar represents phenyl optionally substituted by one or more of the following groups: halogen, CN, C ₁ -C ₆ -alkyl or C ₁ -C ₆ -haloalkyl, especially represents 4-chlorophenyl, 4-cyano phenyl, 4-trifluoromethylphenyl, 3-chlorophenyl, 3-cyanophenyl or 3-trifluoromethylphenyl, or

represents a 5- or 6-membered heteroaryl group each bearing an O, S or N atom, especially thienyl, furyl or pyridyl, which are optionally substituted by one or more of the following groups: halogen, CN, C ₁ -C ₆ -Alkyl or C ₁ -C ₆ -haloalkyl.

The following compounds may be mentioned as examples:

In addition to the above-mentioned one or more compounds selected from sodium ion channel effectors, the mixture of the present invention also includes at least one compound of the following formula (IX), (X) and (XI)

Thiacloprid

Clothianidin

imidacloprid

Compound (IX) is known and disclosed in US 4,849,432.

Compound (X) is known and disclosed in EP-0-375 907-A1.

Compound (XI) is known and disclosed in EP-0-192 060.

The ratio (by weight) of the Na ion channel effector to the compound of formula (IX)-(XI) in the mixture is usually 1:0.1-1:100, preferably 1:1-1:50.

Particularly preferred mixtures according to the invention include the active compound oxadiazole of the formula

Clothianidin of formula (X)

It is also particularly preferred that the mixtures according to the invention include the active compound oxadiazole of the formula

Thiacloprid of formula (IX)

It is also particularly preferred that the mixtures according to the invention include the active compound oxadiazole of the formula

and imidacloprid of formula (XI)

The active compound mixtures (mixtures) according to the invention are suitable for controlling animal pests, especially insects, acarids and nematodes occurring in agriculture, forestry, protection of stored products and materials and hygiene, while being very well tolerated by plants Sexuality and favorable toxicity to warm-blooded animals. They can preferably be used as plant protection agents. They are active against normally sensitive and resistant species and against all or individual stages of development. The aforementioned pests include:

From the order of the Isopoda: eg, Oniscus asellus, flat beetles, squirrels.

Diplopoda: eg, Zebralandia.

From the order of the Chiropods: eg, the frugivorous centipedes, the spp.

General headings: eg, garden crocodile.

Thysanoptera: eg, Formosan silverfish.

Collembola: eg, Armed Collembola.

From the order of Orthoptera: eg, house crickets, Mole crickets, African migratory locusts, Black locusts, desert locusts.

Blattata: eg, Blatta orientalis, Periplaneta americana, Blatta Madeira, Blattella germanica.

From the order Deroptera: eg, European ballworms.

From the order of the Isoptera: eg, Trichotermes.

From the order of Louse: for example, Body Louse, Blood Louse, Jaw Louse, Chewing Louse, Animal Louse.

From the order Thysanoptera: eg, Thrips greenhouse, Thrips tabaci, Thrips palmi, Thrips alfalfa.

From the Heteroptera: eg, Dysdercus intermedius, Dysdercus intermedius, Scutellaria chinensis, temperate bedbugs, long red stinkbug, Dysdercus intermedius.

Homoptera: e.g., Cabbage whitefly, Sweet potato whitefly, Greenhouse whitefly, Cotton aphid, Cabbage aphid, Cryptoxera tea, Euonymus bean, Apple aphid, Apple cotton aphid, Peach aphid, Grape phylloxera, Gall aphids, wheat elongated tube aphids, xenomorphs genus, chrysoprhidis, cereal stalk aphids, green leafhoppers, leafhoppers (Euscelis bilobatus), black-tailed leafhoppers, eucalyptus balls, olives Bead wax scale, gray planthopper, brown planthopper, red kidney scale scale, ivy scale scale, mealybug genus, psyllid genus.

Lepidoptera: e.g., cotton pink bollworm, pine butterfly moth, orchard fall moth, leaf miner (lithocolletis blancardella), apple nest moth, diamondback moth, yellow-brown tent caterpillar, chrysanthemum moth, genus Lithocolletis, cotton miner Moth (Bucculatrix thurberiella), citrus leaf miner, Spodoptera, Spodoptera, Digoptera, Egyptian borer, Helicoptera, Cabbage Spodoptera, Microphagia, Spodoptera . ), spruce-colored tortrix, grape fruit beetle, tea long tortrix, oak green tortrix, Cnaphalocerus spp., rice negative mud worm.

Coleoptera: e.g., furniture beetle, grain beetle, beetle beetle (Bruchidius obtectus), common beetle beetle, longhorn beetle, blue-breathed beetle, potato beetle, horseradish beetle, genus obtectus, rapeseed beetle Golden-headed flea beetle, Mexican bean beetle, cryptophagia, saw beetle, flower elephant, rice elephant, grape black-eared beetle, banana root neck, seed elephant, alfalfa leaf beetle, dermoptera, Trogoderma genus, Toroderma genus, Trichoderma genus, Mesoderma genus, Rapeseed Beetle, Arachnidus genus, Yellow spider beetle, Wheat spider beetle, Trichoderma spp., Chrysanthemum beetles, Pythia spp., Broad-breasted Beetle, May beetle, potato beetle, brown New Zealand ribbed beetle, rice water elephant.

From the order of the Hymenoptera: for example, the genus Pinus, Tetraphyllum, Hairy Ants, House Ants, Vespas.

Diptera: e.g., Aedes, Anopheles, Culex, Orangutan Drosophila, Musca musca, Plethia, Red-headed blowfly, Lucilia, Chrysalis, Anopheles, Gastric Tannia spp., Tickfly, Tickfly, Tannia spp., Derma spp., Garden Mosquito, Swedish Stemfly, Lysia spp., Spinach Fly, Medfly , Olive fruit fly, swamp mosquito, species fly, Liriomyza spp.

From the order of the Fleas: for example, Ceratophyllus, Ceratophyllus spp.

Arachnida: e.g., scorpion (Scorpio maurus), red-spotted spider, Adenophora cerevisiae, genus Auropharidum, genus Phyllosporum, gall mite, rabbit gall mite, citrus gall mite, bovine genus, fan Head ticks, Flower ticks, Hyalophthalum, Ixodes, Pruritus, Itch mite, Sarcoptes, Tarsus, Mosquito californica, Panonychus, Tetranychus, Hemitarsus Acarids, Brachycarps.

Plant-parasitic nematodes include, e.g., Brachysomes spp., D. similarius, D. hemipiercs, Heteroderma spp., Heteroderma spp., Meloidogyne spp., S. spp. The genus, the genus Prunus, and the genus Umbrella.

According to the invention, it is possible to treat all plants and plant parts. Plants are here understood to mean all plants and plant communities, such as desired and undesired wild plants or crops (including naturally occurring crops). Crops can be plants obtained by conventional breeding and optimization methods or by biotechnological and genetic engineering methods or combinations of the above methods, including transgenic plants and including plant cultivars with or without protection of plant breeding rights (Sortenschutzrechte). Parts of plants are to be understood as meaning all above- and below-ground parts and plant organs such as stems, leaves, flowers and roots, examples of which may be mentioned are leaves, needles, branches, trunks, flowers, fruiting bodies, fruits and seeds and Roots, tubers and rhizomes. Plant parts also include harvested plants and plant vegetative bodies and sexual propagation material, for example seedlings, tubers, rhizomes, cuttings and seeds.

The treatment of plants and plant parts according to the invention with the active compound mixtures is carried out by direct application or by acting on their environment, habitat or storage area by customary treatment methods, for example by dipping, spraying, fumigation, misting, spreading, brushing And in the case of propagation material, especially seeds, one or more coatings can also be applied.

The active compound mixture of the present invention can be processed into conventional preparations, such as liquids, emulsions, wettable powders, suspensions, powders, fine powders, pastes, soluble powders, granules, concentrated suspoemulsions, natural formulations impregnated with active compounds. and synthetic materials, as well as polymer-encapsulated microcapsules.

These formulations are produced by known methods, for example by mixing the active compounds with extenders, i.e. liquid solvents and/or solid carriers, optionally with the addition of surfactants, i.e. emulsifiers and/or dispersants, and / or blowing agent.

In the case of using water as an extender, for example, an organic solvent can also be used as a co-solvent. Appropriate liquid solvents mainly include: aromatic hydrocarbons, such as xylene, toluene or alkylnaphthalene, chlorinated aromatic hydrocarbons and chlorinated aliphatic hydrocarbons, such as chlorobenzene, dichloroethane (Chlorethylene) or methylene chloride, aliphatic hydrocarbons such as cyclohexane or paraffins such as petroleum distillates, mineral and vegetable oils, alcohols such as butanol or ethylene glycol and their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl Isobutyl ketone or cyclohexanone, strong polar solvents such as dimethylformamide and dimethylsulfoxide, and water.

Suitable solid carriers are:

Examples include ammonium salts and natural mineral powders such as kaolin, clay, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth, and synthetic mineral powders such as highly disperse silica, alumina and silicates; Suitable solid carriers for granules are: for example, crushed and graded natural rocks, such as calcite, marble, pumice, sepiolite and dolomite, and synthetic granules of inorganic and organic powders, and granules of organic materials, such as sawdust, nut shells , corn cob stems and tobacco stems; suitable emulsifiers and/or foaming agents are, for example, nonionic and anionic emulsifiers, such as polyoxyethylene fatty acid esters, polyoxyethylene fatty alcohol ethers, such as alkylaryl polyethylene glycol ethers Alcohol ethers, alkyl sulfonates, alkyl sulfates, aryl sulfonates and protein hydrolysates; suitable dispersants are, for example, lignin sulfite and methyl cellulose.

Binders such as carboxymethylcellulose and natural or synthetic polymers in the form of powders, granules or latexes, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, and natural phospholipids, such as cephalins and lecithins, can also be used in the formulations, and synthetic phospholipids. Other additives may be mineral and vegetable oils.

It is also possible to use colorants such as inorganic pigments such as iron oxide, titanium oxide and Prussian blue, as well as organic dyes such as alizarin dyes, azo dyes and metal phthalocyanine dyes, and trace nutrients such as iron, manganese, boron , copper, cobalt, molybdenum and zinc salts.

The formulations generally contain 0.1-95% by weight, preferably 0.5-90% by weight, of active compound.

The active compounds of the present invention can also be present through their commercially available preparations and the application forms prepared from the above-mentioned preparations in mixtures with other active compounds, such as insecticides, attractants, disinfectants, bactericides, acaricides pesticides, nematicides, fungicides, plant growth regulators or herbicides. Insecticides include, for example, phosphoric acid esters, carbamates, carboxylates, halogenated hydrocarbons, phenylureas, substances produced by microorganisms, and the like.

Particularly preferred co-components are, for example, the following:

Fungicides:

Aldimorph, Amprodronic Acid, Amprodronate Potassium Salt, Andoprim, Difenazol, Oconazole, Azoxystrobin,

Benalaxyl, Maitrudine, Benomyl, Benzenoic Acid, Isobutyl Benzenoate, Bialaphos, Lexa, Biphenyl, Bifentriazole, Blasticidin, Fuconazole, B Pyrimidinylsulfonate, Buthiazine, Calcium Sulfur, Capsimycin, Captafol, Captan, Carbendazim, Wiltazol, Carvon, Manganese, Mebendazole, Benmidazole, Demaoxan, Chloropicrin, Chlorothalonil, Promethazil, Clozylacon, Thiazaline, Cymoxanil, Cyproconazole, Cyprodinil, Eclostrobin,

Profencarb, Diclofenac, Benclotriazole, Diclofluanid, Pyridoxone, Clonitramine, Dimethocarb, Difenocarb, Difenocarb, Dimethylen, Dimethomorph, Diniconazole, Diniconazole Alcohol-M, dinocap, diphenylamine, pyridinil, fenphos, dicyanoanthraquinone, dodecyclomorph, dodine, difendone,

Difenfofos, Oxaconazole, Etoconazole, Pyrimethol, Terendazim,

Oxaconazole, Mipronil, Chlorpyrimidol, Nibendazole, Furafil, Seedcoating Ester, Seed Dressing, Fenpropidin, Fenpropimorph, Triphenyltin Acetate, Hydroxytriphenyltin, Thiam Iron, pyrizone, fluazinam, fluorinated biphenyl, fluorinated, fluoroquinazole, flurizol, flusilazole, sulfazone, flunamide, fuconazole, folpet, triethyl Aluminum phosphonate, sodium triethylphosphonate, tetrachlorophthalide, wheat suingin, furaxyl, furazolin, fenfen, furconazole, furetazole, seed dressing amine,

Biguanide salt, hexachlorobenzene, hexaconazole, hymexazol,

Imazalil, imidazole, biguanide octine, double octaguanide salt, biguanide octyl acetate, Iodocarb, cloconazole, isofridazine, iprodione, Irumamycin, rice blastin, chlorbendone,

Kasugamycin, imimidium, copper-containing fungicides such as: copper hydroxide, copper naphthenate, copper king, copper sulfate, copper oxide, copper quinoline and Bordeaux mixture,

Mancocopper, Mancozeb, Maneb, Meferimzone, Azoxyprodil, Rustamine, Metalaxyl, Meconazole, Sulfurcarb, Furfuramide, Disenlian, Phenylpyrrole, Thiobacillin Amine, midomycin, myclobutanil, triclocarbazol,

Fumagnesium Nickel, Propylene Glycol, Fluoxetine Alcohol,

Furamide, Oxafaxyl, Oxamocarb, Oxamethalone, Oxyprofen, Oxyfenthiin,

Paclobutrazol, blastic acid ester, penconazole, pendicloron, chlorfenfos, domomycin, peripridine, polyoxamycin, Polyoxorim, allyl benzothiazole, prochloraz, procymidone, propamocarb , Propanosine-sodium, propiconazole, procyon, pyriprofos, acetoxime, pyrimethanil, pyrimethanil, pyrimethanone, clopifur,

Quinconazole, pentachloronitrobenzene,

Sulfur and sulfur preparations,

Tebuconazole, Tetraclophthalein, Tetrachloronitrobenzene, Tetracyclazole, Tetrafluconazole, Thiabendazole, Thipronil, Bromfluconazole, Thiophanate-Methyl, Thiram, Thiocyanate , tolclofos-methyl, toluene flusulfonamide, triadimefon, triadimenol, leaf rust, imidazosin, salicylamine, tricyclazole, tridemorpholine, fluconazole, azinamide, sterilization azole,

Uniconazole,

Validamycin A, vinclozolin, difenazazole,

cypromethanil, zineb, thiram, and

Imazethapyr (Dagger G)

OK-8705, OK-8801,

α-(1,1-dimethylethyl)-β-(2-phenoxyethyl)-1H-1,2,4-triazole-1-ethanol,

α-(2,4-dichlorophenyl)-β-fluoro-b-propyl-1H-1,2,4-triazole-1-ethanol,

α-(2,4-dichlorophenyl)-β-methoxy-a-methyl-1H-1,2,4-triazole-1-ethanol,

α-(5-methyl-1,3-dioxan-5-yl)-β-[[4-(trifluoromethyl)-phenyl]-methylene]-1H-1,2,4 -triazole-1-ethanol,

(5RS, 6RS)-6-hydroxy-2,2,7,7-tetramethyl-5-(1H-1,2,4-triazol-1-yl)-3-octanone,

(E)-a-(methoxyimino)-N-methyl-2-phenoxy-phenylacetamide,

1-isopropyl{2-methyl-1-[[[1-(4-methylphenyl)-ethyl]-amino]-carbonyl]-propyl}-carbamate,

1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)-ethanone-O-(phenylmethyl)-oxime,

1-(2-Methyl-1-naphthyl)-1H-pyrrole-2,5-dione,

1-(3,5-dichlorophenyl)-3-(2-propenyl)-2,5-pyrrolidinedione,

1-[(Diiodomethyl)-sulfonyl]-4-methyl-benzene,

1-[[2-(2,4-dichlorophenyl)-1,3-dioxolan-2-yl]-methyl]-1H-imidazole,

1-[[2-(4-chlorophenyl)-3-phenyloxiranyl]-methyl]-1H-1,2,4-triazole,

1-[1-[2-[(2,4-Dichlorophenyl)-methoxy]-phenyl]-vinyl]-1H-imidazole,

1-methyl-5-nonyl-2-(phenylmethyl)-3-pyrrolidinol,

2',6'-Dibromo-2-methyl-4'-trifluoromethoxy-4'-trifluoro-methyl-1,3-thiazole-5-carboxanilide,

2,2-dichloro-N-[1-(4-chlorophenyl)-ethyl]-1-ethyl-3-methyl-cyclopropanecarboxamide,

2,6-dichloro-5-(methylthio)-4-pyrimidinyl-thiocyanate,

2,6-Dichloro-N-(4-trifluoromethylbenzyl)-benzamide,

2,6-dichloro-N-[[4-(trifluoromethyl)-phenyl]-methyl]-benzamide,

2-(2,3,3-triiodo-2-propenyl)-2H-tetrazole,

2-[(1-methylethyl)-sulfonyl]-5-(trichloromethyl)-1,3,4-thiadiazole,

2-[[6-Deoxy-4-O-(4-O-methyl-β-D-glucopyranosyl)-a-D-glucopyranosyl]-amino]-4-methoxy-1H- pyrrolo[2,3-d]pyrimidine-5-carbonitrile,

2-aminobutane,

2-Bromo-2-(bromomethyl)-glutaronitrile,

2-chloro-N-(2,3-dihydro-1,1,3-trimethyl-1H-inden-4-yl)-3-pyridinecarboxamide,

2-Chloro-N-(2,6-dimethylphenyl)-N-(isothiocyanatomethyl)-acetamide,

2-Phenylphenol (OPP),

3,4-dichloro-1-[4-(difluoromethoxy)-phenyl]-1H-pyrrole-2,5-dione,

3,5-dichloro-N-[cyano[(1-methyl-2-propynyl)-oxyl]-methyl]-benzamide,

3-(1,1-Dimethylpropyl-1-oxo-1H-indene-2-carbonitrile,

3-[2-(4-Chlorophenyl)-5-ethoxy-3-isoxazolidinyl]-pyridine,

4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide,

4-methyl-tetrazolo[1,5-a]quinazolin-5(4H)-one,

8-(1,1-Dimethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro[4.5]decane-2-methylamine,

8-hydroxyquinoline sulfate (sulfat),

9H-Xanthene-2-[(phenylamino)-carbonyl]-9-carboxhydrazide,

bis-(1-methylethyl)-3-methyl-4-[(3-methylbenzoyl)-oxy]-2,5-thiophene dimethyl ester,

cis-1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)-cycloheptanol,

cis-4-[3-[4-(1,1-dimethylpropyl)-phenyl-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride,

[(4-Chlorophenyl)-azo]-ethyl cyanoacetate,

potassium bicarbonate,

Methyltetramercaptan sodium salt,

1-(2,3-Dihydro-2,2-dimethyl-1H-inden-1-yl)-1H-imidazole-5-carboxylic acid methyl ester,

N-(2,6-Dimethylphenyl)-N-(5-isoxazolylcarbonyl)-DL-alanine methyl ester,

N-(chloroacetyl)-N-(2,6-dimethylphenyl)-DL-alanine methyl ester,

N-(2,3-dichloro-4-hydroxyphenyl)-1-methyl-cyclohexanecarboxamide,

N-(2,6-Dimethylphenyl)-2-methoxy-N-(tetrahydro-2-oxo-3-furyl)-acetamide,

N-(2,6-Dimethylphenyl)-2-methoxy-N-(tetrahydro-2-oxo-3-thienyl)-acetamide,

N-(2-Chloro-4-nitrophenyl)-4-methyl-3-nitro-benzenesulfonamide,

N-(4-cyclohexylphenyl)-1,4,5,6-tetrahydro-2-pyrimidinamine,

N-(4-hexylphenyl)-1,4,5,6-tetrahydro-2-pyrimidinamine,

N-(5-chloro-2-methylphenyl)-2-methoxy-N-(2-oxo-3-oxazolidinyl)-acetamide,

N-(6-methoxy)-3-pyridyl)-cyclopropanecarboxamide,

N-[2,2,2-Trichloro-1-[(chloroacetyl)-amino]-ethyl]-benzamide,

N-[3-chloro-4,5-bis-(2-propynyloxy)-phenyl]-N'-methoxy-formimidamide (methahimidamid),

N-Formyl-N-hydroxy-DL-alanine sodium salt,

[2-(Dipropylamino)-2-oxoethyl]-ethyl phosphorothioate O, O-diethyl ester,

Phenylpropyl phosphorothioate O-methyl S-phenyl ester,

1,2,3-Benzothiadiazole-7-thiocarboxylate S-methyl ester,

Spiro[2H]-1-benzopyran-2,1'(3'H)-isobenzofuran]-3'-one,

Bactericides:

Bronopol, Dichlorophen, Trichloromethylpyridine, Nickel Niramide, Kasugamycin, Octthinone, Furancarboxylic Acid, Oxytetracycline, Allylbenthiazole, Streptomycin, Tecloftin, Copper Sulfate and others Copper preparations.

Insecticides/Acaricides/Nematocides:

Abamectin, acephate, acetamiprid, flumethrin, acetamicarb, aldicarb, sulfonecarb, cis-cypermethrin, alpha-cypermethrin, amitraz, abamectin, AZ 60541, Aizadin, methyl pyroxaphos, ethyl azinphos, azinphos, triazotin,

Bacillus japonicus, Bacillus sphaericus, Bacillus subtilis, Bacillus thuringiensis, Baculoviruses, Beauveria bassiana, Beauveria bassiana, Dihexacarb, Carbosulfan, sulfonate, benzapter, beta-cyfluthrin , Bifenazate, Bifenthrin, Bioethanomethrin, Biological Permethrin, Secbucarb, Brothion A, Hexacarb, Buprofezin, Tepyrifos, Butanonecarb, Butylpyridaben

Thiamifos, carbaryl, carbofuran, trithion, carbosulfan, cartap, ChloethoCarb, oxychloride, chlorfenapyr, chlorpyrifos, chlorpyrifos, Chlorpyrifos-methyl, Chlovaporthrin, cis-resmethrin, cis-permethrin, Clocythrin, Cyclothrin, Tetrafenazin, Cyclonil, Cycloprene, Vethrin, Cyfluthrin, Cyhalothrin, Three Cyclotin, Cypermethrin, Cyromazine

Deltamethrin, Demeton methyl, Demeton-methyl isomer, Demeton-methyl isomer, Diafenthiuron, Diazinon, Dichlorvos, Diflubenzuron, Dimethoate, Methamphetamine, Difenpyr, Dithiocarbamate, Iodopoxime, Phenoxypyridine

Efusilanate, Emamectin, D-styrenthrin, Endosulfan, Inch, Eprinomectin, S-Cenvalerate, Ethiobencarb, Ethion, Femiphos, Etoproxil, Terbenoxazole, Ethifen Pyrimithion

Fenamifos, Fenazafen, Fenbutatin, Fenitrothion, Fenthiocarb, Fenoxacrim, Fenoxycarb, Fenpropathrin, Fenpyrad, Fenpyrithrin, Fenifaben, Fenvalerate, Fipronil, Fluoride Pyridine, pyridoxuron, delmafluthrin, hexafenuron, flucyvalerate, flubenzuron, flutenzine, fluvalinate, tefenthion, fenfenfos, thiazophos, Fubfenprox, furanthrin line prestige

Granular virus

Terbufenozide, BHC, heptenphos, hexaflumuron, hexythiazox, methoprene, imidacloprid, chlorazophos, isofenphos, oxazophos, abamectin

nuclear polyhedrosis virus

Beta-cyhalothrin, flupropoxycarbamide

Malathion, Methion, Metaldehyde, Methamidophos, Metharhizium anisopliae, Metharhizium flavoviride, Methaphos, Methiocarb, Methomyl, Methoxyfenozide, Methofen, Methoxyfen, Acetyl Phosphate, Milmectin, Monocrotophos

Dibromophos, nitenpyram, nitrothiazide, diflufenuron

Omethoate, Shaxicarb, Phosphate Sulfoxide

Paecilomyces fumigatus, parathion A, methyl parathion, permethrin, Daofengsan, phorate, phosthion, imidophos, phosphamide, phoxim, pirimicarb , pirimiphos-ethyl, pirimiphos-methyl, profenofos, monsoxur, propoxur, prothion, phathion, pymetrozine, pyrazophos, antipyrethrum, pyrethrin, pyridaben , Pyridathion, pyrimifen, pyriproxyfen

Quetiaphos

Ribavirin

Chalpine, thiometaphos, Selamectin, flusilicate, Acetyl 105, Sulfotep, thioprofos

Fluvalinate, tebufenozide, tebufenpyrad, pyrimprofos, hexafenuron, tefluthrin, teflufos, metenfen, terbufos, dimethox, octyl-cypermethrin, Thiamethoxam, Thiapronil, Thiatriphos, Thiocyclad, Thiadicarb, Monoclocarb, Difibrate, Deltacypermethrin, Permetrimethrin, Benfenthrin, Fenpyramid, Triazophos, Thiazuron, Clomidazole, Trichlorfon , thaluron, mixed thicarb

Aphidol, flurazole, McCotel

YI 5302

Cypermethrin, zolaprofos

(1R-cis)-[5-(phenylmethyl)-3-furyl]-methyl-3-[(dihydro-2-oxo-3(2H)-furylidene)-methyl] -2,2-Dimethylcyclopropanecarboxylate

(3-phenoxyphenyl)-methyl-2,2,3,3-tetramethylcyclopropanecarboxylate

1-[(2-Chloro-5-thiazolyl)methyl]tetrahydro-3,5-dimethyl-N-nitro-1,3,5-triazine-2(1H)-imine

2-(2-Chloro-6-fluorophenyl)-4-[4-(1,1-dimethylethyl)phenyl]-4,5-dihydro-oxazole

2-(Acetoxy)-3-dodecyl-1,4-naphthalenedione

2-Chloro-N-[[[4-(1-phenylethoxy)-phenyl]-amino]-carbonyl]-benzamide

2-Chloro-N-[[[4-(2,2-dichloro-1,1-difluoroethoxy)-phenyl]-amino]-carbonyl]-benzamide

3-Methylphenyl-propyl carbamate

4-[4-(4-ethoxyphenyl)-4-methylpentyl]-1-fluoro-2-phenoxy-benzene

4-Chloro-2-(1,1-dimethylethyl)-5-[[2-(2,6-dimethyl-4-phenoxyphenoxy)ethyl]thio]-3 (2H)-Pyridazinone

4-chloro-2-(2-chloro-2-methylpropyl)-5-[(6-iodo-3-pyridyl)methoxy]-3(2H)-pyridazinone

4-Chloro-5-[(6-chloro-3-pyridyl)methoxy]-2-(3,4-dichlorophenyl)-3(2H)-pyridazinone

Bacillus thuringiensis EG-2348 strain

2-benzoyl-1-(1,1-dimethylethyl)-hydrazinobenzoic acid,

2,2-Dimethyl-3-(2,4-dichlorophenyl)-2-oxo-1-oxaspiro[4,5]dec-3-en-4-ylbutyrate

[3-[(6-Chloro-3-pyridyl)methyl]-2-thiazolidinyl]-cyanamide

Dihydro-2-(nitromethylene)-2H-1,3-thiazine-3(4H)-carbaldehyde

[2-[[1,6-Dihydro-6-oxo-1-(phenylmethyl)-4-pyridazinyl]oxy]ethyl]-urethane

N-(3,4,4-Trifluoro-1-oxo-3-butenyl)-glycine

N-(4-chlorophenyl)-3-[4-(difluoromethoxy)phenyl]-4,5-dihydro-4-phenyl-1H-pyrazole-1-carboxamide

N-[(2-Chloro-5-thiazolyl)methyl]-N’-methyl-N”-nitro-guanidine

N-methyl-N'-(1-methyl-2-propenyl)-1,2-hydrazinedithioformamide

N-methyl-N'-2-propenyl-1,2-hydrazinedithioformamide

[2-(Dipropylamino)-2-oxoethyl]-ethyl phosphorothioate O, O-diethyl ester

Mixtures with other known active compounds, such as herbicides or with fertilizers and growth regulators, are also possible.

When used as insecticides, the active compound mixtures according to the invention can also be present in the commercially available formulations and in the application forms prepared from the abovementioned formulations in admixture with synergists. Synergists are compounds which increase the activity of the active compounds, without it being necessary for the synergist added to be active itself.

The active compound content of the use forms prepared from the commercial formulations can vary within wide ranges. The active compound concentration in the use forms is 0.0000001 to 95% by weight of active compound, preferably 0.0001 to 1% by weight.

Administration is carried out in the usual manner suitable for the application form.

When used for controlling sanitary pests and pests in stored goods, the active compound mixture has excellent residual activity on wood and clay and very good stability to alkalis on calcified substrates.

The active compound mixture of the present invention is not only active against plant pests, hygienic pests and pests in stored goods, but also in the field of veterinary medicine for controlling animal parasites (ectoparasites), such as hard ticks, soft ticks, mange mite, Also active are spider mites, flies (biting and sucking), parasitic fly larvae, lice, head lice, feather lice and fleas. These parasites include:

From the order of the lice, e.g., Haemalopus, Pthirus, Pthirus spp., Pthirus spp.;

Trichophaera and the suborders Obtuse and Slenderceramia, e.g., Pleurotus spp., Menopons pp., Pyrophyllus spp., Lepikentron spp., Werneckiella spp., Lepikentron spp., Lepikentron spp., Lepikentron spp., Lepikentron spp., Lepikentron spp., Lepikentron spp., Lepikentron spp. ;

From the order Diptera and from the suborders Longocera and Brachycera, e.g., Aedes, Anopheles, Culex, Gnats, Euphoria, Chrysalis, Lutzomyia spp., Culicoides, Zephyr . Genus, Glossia, Calliphora, Lucilia, Chrysalis, Wohlfahrtia spp., Sarcophagia, Cystia, Derma, Gastonia, Lipopena, Lipoptena spp., Tick

From the order of Fleas, e.g., Fleas, Ctenocephalus, Ctenophora, Ceratophyllus

Heteroptera, e.g., Bedbugs, Vertebras, Red-bellied Stinkbugs, Oculus

Blattata, e.g., Blatta orientalis, Periplaneta americana, Blattella germanica, Blattella

Acarinae and suborders of Metastigmata and Mesostigmata, e.g., Acarids, Mesophysalis, Pyrocystis, Ixodes, Anthropophys, Bovine, Derma, Haemophysalis spp. , Hyalophthalum spp., Rhizocephalus spp., Dermatophthora spp., Pythias spp., Pulmonary stinger spp., Thoracicus spp., Varroa spp.

Acarina (former stigmata) and Acarina (aspirata), e.g., Tarsus spp., Ichimangi, Avulina spp., Sarcocarpus, Pleurotus spp., Demodex Acarids, Chiggers, Yakyids, Acarids, Tyrophagous, Xylophilus, Intracervical Acarids, Pteromyces, Pruritus, Pruritus, Ear Acarids, Scabies, Scab mites, Pimple mites, Cytomangi, Thylemids.

The active compound mixture of the present invention is also suitable for controlling arthropods infesting agricultural livestock such as cattle, sheep, goats, horses, pigs, donkeys, camels, buffaloes, rabbits, chickens, turkeys, ducks, geese, bees, etc. Domestic animals such as dogs, cats, caged birds, aquarium fish and so-called laboratory animals such as voles, guinea pigs, rats and mice. By controlling the aforementioned arthropods, the aim is to reduce animal mortality and production (meat, milk, fur, hides, eggs, honey, etc.), so that the use of the active compound mixture according to the invention makes animal husbandry more economical and simpler.

When used in the veterinary field, the active compound mixture according to the invention can be administered enterally by known methods, for example in the form of tablets, capsules, drinks, drenches, granules, ointments, boluses, feeding sessions and suppositories ; parenteral administration, e.g. by injection (intramuscular, subcutaneous, intravenous, intraperitoneal, etc.), implantation; nasal administration; transdermal administration, e.g., by soaking or bathing, spraying, splashing Or rubbing, washing and dusting can also be carried out by means of shaped articles containing active compounds, such as collars, earrings, tail ornaments, limb rings (belts), bridles, decorative utensils, etc.

When used for livestock, poultry, pets, etc., the active compound mixture can be used in the form of preparations (such as powders, emulsions, flowables), which include 1-80% by weight of the active compound, directly used or used after 100-10000 times diluted , or used as a medicinal bath.

In addition, it has been found that the active compound mixtures according to the invention also have a strong insecticidal activity against insects which damage industrial materials.

The following insects are listed as examples and preferably, but not limited to:

Coleoptera insects such as

North American house beetle, green tiger beetle (Chlorophorus pilosis), furniture beetle, dead wood beetle, wing beetle, Dendrobium pertinex, pine bud beetle, pine product beetle (Priobium carpini), brown powder beetle Lyctus africanus, Lyctus africanus, Lyctus pubescens, Lyctus pubescens, Trogoxylonaequale, Lyctus africanus, Lyctus africanus, Lyctus spp. .

Dermatoptera, such as

Blue-black Horntail, Spruce Horntail, Taiga Horntail, Urocerus augur

termites such as

Carpenter termites (Kalotermes flavicollis), Matou termites, Indian termites, European and American termites, Reticulitermess antonensis, Reticulitermes lucifugus, Darwin's Australian termites, Nevada ancient termites, Taiwan milk termites

Thysanoptera, e.g. Taiwan silverfish

Industrial materials in the context of the invention are understood to mean non-living (nicht-lebende) articles, such as preferably plastics, adhesives, glues, paper and board, leather, wood, (processed) wood products and coatings.

Wood and wood products are materials in particular that require optimal protection from insect attack.

Wood and wood products which can be protected by using the composition according to the invention or mixtures containing it are understood to mean, for example:

Timber for construction, wooden beams, railroad ties, bridge components, ship bows, wooden vehicles, boxes, shelves, containers, poles, wood paneling, wooden windows and doors, plywood, chipboard, in house building or architectural details Joinery or woodwork commonly used in the carpentry trade.

The active compounds can be used directly or in concentrated form or in the customary formulations, such as powders, granules, solutions, suspensions, emulsions or pastes.

The aforementioned formulations can be prepared by known methods, for example by mixing the active compounds with at least one solvent or diluent, emulsifiers, dispersants and/or binders or fixatives, water repellents and, if desired, driers and UV stabilizers and, if desired, dyes and pigments and other processing aids.

The pesticidal compositions or concentrates for the protection of wood and wood products comprise the active compounds according to the invention in concentrations of 0.0001 to 95% by weight, in particular of 0.001 to 60% by weight.

The amount of composition or concentrate to be used is determined according to the species of insect and the occurrence and medium. The optimum application rates can each be determined by series of experiments in application. In general, however, it is sufficient to use 0.0001 to 20% by weight, preferably 0.001 to 10% by weight, of active compound, based on the material to be protected.

Suitable solvents and/or diluents are organic chemical solvents or solvent mixtures and/or low volatility oily or oily organic solvents or solvent mixtures and/or polar organic solvents or solvent mixtures and/or water, if required Emulsifier and/or wetting agent.

Organic solvents used with preference are oily or oily solvents with an evaporation value greater than 35 and a flash point greater than 30°C, and preferably greater than 45°C. The aforementioned water-insoluble and low-volatility oily or oily solvents are suitable mineral oils or their aromatic fractions or solvent mixtures containing mineral oils, preferably white spirit, petroleum and/or alkylbenzenes.

It is preferred to use mineral oil with a boiling range of 170-220°C, petroleum solvent with a boiling range of 170-220°C, spindle oil with a boiling range of 250-350°C, petroleum and aromatic hydrocarbons with a boiling range of 160-280°C, turpentine, etc.

In a preferred embodiment, liquid aliphatic hydrocarbons with a boiling range of 180-210° C. or high boiling mixtures of aromatic and aliphatic hydrocarbons with a boiling range of 180-220° C. and/or spindle oils and/or monochlorinated naphthalenes are used, Alpha-monochloronaphthalene is preferred.

Low-volatility organic oily or oil-like solvents with an evaporation value greater than 35 and a flash point greater than 30 °C and preferably greater than 45 °C may be partially replaced by high or medium volatility organic solvents, provided that the solvent mixture also has an evaporation value greater than 35 and a flash point The point is greater than 30° C. and preferably greater than 45° C., and the insecticide-fungicide mixture is soluble or emulsifiable in the solvent mixture.

In a preferred embodiment, some of the organic solvent or solvent mixture is replaced by an aliphatic polar organic solvent or solvent mixture. Preference is given to using aliphatic organic solvents containing hydroxyl and/or ester and/or ether groups, such as glycol ethers, esters and the like.

The organic chemical binders used in the present invention are synthetic resins and/or adhesive drying oils known per se, which are water-dilutable and/or soluble or dispersible or emulsified in the organic chemical solvents used, in particular from the following Composition of matter or adhesives containing: acrylate resins (Acrylatharz), vinyl resins such as polyvinyl acetate, polyester resins, polycondensation or polyaddition reaction resins, polyurethane resins, alkyd resins or modified Alkyd resins, phenolic resins, hydrocarbon resins such as indene/coumarone resins, silicone resins, drying vegetable oils and/or drying oils and/or physically drying adhesives based on natural and/or synthetic resins .

Synthetic resins used as binders can be used in the form of emulsions, dispersions or solutions. Bitumen or bituminous substances can also be used as binders in amounts of up to 10% by weight. It is also possible to use dyes, pigments, water repellents, odor-masking agents and inhibitors or corrosion inhibitors etc. known per se.

Preferably at least one alkyd resin or modified alkyd resin and/or a drying vegetable oil is included in the composition or concentrate according to the invention as an organic chemical binder. The present invention preferably uses alkyd resins having an oil content greater than 45% by weight, preferably 50-68% by weight.

All or some of the above binders may be replaced by fixatives (mixtures) or plasticizers (mixtures). The purpose of adding these additives is to prevent evaporation and crystallization or precipitation of the active compounds. They preferably replace 0.01 to 30% of the binder (based on 100% of the binder used).

Plasticizers Chemicals derived from phthalates, such as dibutyl phthalate, dioctyl phthalate, or benzyl butyl phthalate, phosphate esters, such as phosphoric acid Tributyl, adipates such as di-(2-ethylhexyl)adipate, stearates such as butyl stearate or amyl stearate, oleates such as butyl oleate Esters, glyceryl ethers or high molecular weight glycol ethers, glycerides and p-toluene sulfonates.

Fixatives are chemically based on polyvinyl alkyl ethers, such as polyvinyl methyl ether, or ketones, such as benzophenone or ethylenebenzophenone.

Other suitable solvents or diluents are especially water, if desired in admixture with one or more of the abovementioned organic chemical solvents or diluents, emulsifiers and dispersants.

A particularly effective method of wood protection is by mass impregnation methods, for example by vacuum, double vacuum (Doppelvakuum) or pressurized methods.

Ready-to-use compositions may also include other insecticides if desired, and one or more fungicides if desired.

Other mixing components are preferably those insecticides and fungicides mentioned in WO 94/29268. The compounds described in this document also expressly form part of the present application.

Particularly preferred mixing components that may be mentioned are insecticides such as chlorpyrifos, phoxim, flusalthrin, cis-cypermethrin, cyfluthrin, cypermethrin, deltamethrin, permethrin, imidacloprid, acetamiprid , diflubenzuron, hexaflumuron, tetrafluthrin, thiacloprid, Methoxyphenoxid and triflumuron, and fungicides such as oxyconazole, hexaconazole, oxyconazole, propiconazole, tebuconazole, Cyproconazole, Meconazole, Imazalil, Champagazol, Toluene Flusulfonamide, 3-Iodo-2-Proynyl-Butylcarbamate, N-Octyl-isothiazolin-3-one and 4,5-dichloro-N-octylisothiazolin-3-one.

The mixtures according to the invention can also be used for the protection of various objects from the colonization of animals and plants, especially objects in contact with sea water or salt water, such as ship hulls, observation screens, nets, ship hull structures, docks and signaling systems.

Due to the sedentary oligochaetes, such as Saccharidae and crustaceans and Ledamorpha (Minghe), such as various Minghe and Kaiminghe, or Barnacles (barnacle insects), such as Barnacles or Ledamorpha Myogonia colonization increases hull friction and significantly increases operating costs due to increased energy consumption and frequent dry docking.

Also colonized are seaweeds, such as the genus Hyacinthus and Sesquita, particularly important by the attachment and infestation of the resident molluscs (Cilipedes), which belong to the cirripedes (Cilipedes crustaceans). animal).

Surprisingly, it has now been found that the mixtures according to the invention have a pronounced antifouling (anticolonization) effect either alone or in combination with other active compounds.

By using the mixture according to the invention, either alone or in combination with other active compounds, the use of heavy metals such as, for example, di(trialkyltin) sulfide, tri-n-butyltin laurate, tri-n-butyltin chloride, copper (I ), triethyltin chloride, tri-n-butyl (2-phenyl-4-chlorophenoxy)-tin, tributyltin oxide, molybdenum disulfide, antimony oxide, polybutyl titanate, benzene trichloride Base-(bipyridyl)-bismuth, tri-n-butyltin fluoride, manganese ethylenedithiocarbamate, zinc dimethyldithiocarbamate, zinc ethylenedithiocarbamate, 2-pyridinethiol Zinc and copper salts of 1-oxides, zinc bisdimethyldithiocarbamoyl ethylenebisthiocarbamate, zinc oxide, copper(I) ethylenebisdithiocarbamate, thiocyanate Copper, copper naphthenate and tributyltin halide, or significantly reduce the use concentration of these compounds.

If appropriate, the ready-to-use antifouling paints can also comprise other active compounds, preferably algicides, fungicides, herbicides, molluscicides or other antifouling active compounds.

Suitable components which are preferably mixed with the antifouling compositions of the invention are:

Algicides, such as

2-tert-butylamino-4-cyclopropylamino-6-methylthio-1,3,5-triazine, dichlorophen, diuron, indochine, triphenyltin acetate, isoproturon , Mebenthiuron, Oxyfluorfen, Algaquinone and Terbutin,

fungicides, such as

Benzo[b]thiophene carboxylic acid cyclohexanamide S, S-dioxide, fenzazolin, Fluorfolpet, 3-iodo-2-propynylbutylcarbamate, tolueneflusulfonamide and azoles such as

Oxyconazole, cyproconazole, oxyconazole, hexaconazole, metconazole, propiconazole and tebuconazole;

molluscicides, such as

Triphenyltin acetate, metaldehyde, methiocarb, spiroxamine, thiodicarb, and musulur;

or commonly used antifouling active compounds such as

4,5-dichloro-2-octyl-4-isothiazolin-3-one, diiodomethyl paratryl sulfone, 2-(N,N-dimethylthiocarbamoylthio)-5-nitro Thiazolyl, potassium, copper, sodium and zinc salts of 2-pyridinethiol 1-oxide, pyridinetriphenylborane, tetrabutyldistannoxane, 2,3,5,6-tetrachloro-4 -(methylsulfonyl)-pyridine, 2,4,5,6-tetrachloroisophthalonitrile, tetramethylthiuram disulfide and 2,4,6-trichlorophenylmaleimide.

The antifouling compositions used comprise the active compounds according to the invention in concentrations of 0.001 to 50% by weight, in particular 0.01 to 20% by weight, in the admixtures according to the invention.

Furthermore, the antifouling compositions of the present invention include conventional components disclosed in, for example, Ungerer, Chem.

In addition to the algicides, fungicides, molluscicides and the insecticidally active compounds according to the invention, the antifouling paints also include in particular binders.

Examples of known binders include polyvinyl chloride in solvent systems, chlorinated rubber in solvent systems, acrylic resins in solvent systems, especially aqueous systems, vinyl chloride/vinyl acetate copolymers in the form of aqueous dispersions or organic solvent systems Butadiene/styrene/acrylonitrile rubber, drying oils such as linseed oil, resin esters or with tar or bitumen, asphalt and epoxy compounds, small amounts of chlorinated rubber, chlorinated polypropylene and vinyl Modified hard resin formed by mixing resins.

If desired, inorganic pigments, organic pigments or dyes, which are preferably insoluble in salt water, are also included in the paint. Coatings may also contain substances such as rosin to provide controlled release of the active compound. Coatings may also include plasticizers, modifiers to affect rheological properties, and other conventional components. It is also possible to add the compounds according to the invention or the aforementioned mixtures to self-polishing antifouling systems.

The active compound mixtures are also suitable for controlling pests, especially insects, spiders and mites, which occur in closed spaces such as apartments, factories, offices, carriages and the like. They can be used alone or in admixture with other active compounds and with other active compounds and adjuvants in domestic insecticide formulations for the control of the above-mentioned pests. They are insecticidally active against sensitive and resistant species and against all stages of development. These pests include:

From the order of the scorpions, for example Buthus occitanus.

Acariles, for example, Persian acarids, Acarina spp., Mollus sp., Chicken skin mite, House food mite, Orthodnis africanus, Rhizocephalus blood red, Chigger (Trombicula alfreddugesi), Neutrombicula autumnalis, House Dust mites, dust mites.

From the order of the Arachnidae, for example, Corididae, Arachnididae.

From the order of the blind spiders, for example, Pseudoscorpiones chelifer, Pseudoscorpiones cheiridium, Opiliones phalangium.

Isopoda, such as woodworms, mouse women.

Diplopoda, such as Zebraland, Pinus genus.

From the order of the Chiropods, for example, the genus Centipede.

From the order of the Zygentomas, for example, Cullina, Formosa, Lepismodes inquilinus.

From the order of Blattata, such as Blattella orientalis, Blattella germanica, Blattella asahinai, Blattella Madeira, Blattella spp., Blattella, Periplaneta australis, Periplaneta americana, Periplaneta brown spot, Black chest Periplaneta, long bearded cockroach.

Leaping suborders, such as house crickets.

From the order of Deroptera, such as European ballworms.

From the order of the Isoptera, for example, the genus Carpentertermes, Termites.

From the order of Rodentia, for example, the genus Lepinatus, the genus Amygdalis.

From the order of Coleoptera, for example, the genus Toroderma, Trichoderma, Dermoptera, Long-headed Beetle, Cryptotarsus, Arachnida, Grain Beetle, Grain Weevil, Rice Weevil, Corn Beetle, and Medicinal Herb Beetle.

Diptera, e.g. Aedes aegypti, Aedes albopictus, Aedes taeniorhynchus, Anopheles spp., Blowflies, Mafly, Culex fasciatus, Culex apes, Culex tarsalis, Drosophila, Drosophila , Housefly, Phlebos, Sarcophaga carnaria, Gnat, Stable fly, Tipula paludosa.

From the order of Lepidoptera, for example, the wax moth, the wax moth, the Indian spotted moth, the meal moth, the sack moth, and the meal moth.

From the order of the Fleas, for example Ctenocephalis canis, Ctenocephalus felis nominative subspecies, Human fleas, Pythias dermatophila, Pythias imina.

From the order of the Hymenoptera, for example, the ants of the broadspread ants, the ants of the ants, the ants of the black ants, Lasius umbratus, the house ants, the genus Paravespula, the pavement ants.

Louse, eg head lice, body lice, pubic lice.

From the suborder of Heteroptera, for example, tropical bed bugs, temperate bed bugs, long red bugs, infesting triatomine bugs.

In the field of household insecticides, they can be used alone or in combination with other suitable active compounds, such as phosphates, carbamates, pyrethroids, growth regulators or selected from other known classes of insecticides. The active compounds are used in combination.

They can be used in aerosol form, non-pressurized spray products such as spray by pumps and sprayers, automated spray systems, aerosol generators, foams, gels, vaporizers with vaporizing sheets made of cellulose or polymers, liquids Evaporators, gel and thin-film evaporators, pusher evaporators, energy-free or passive evaporation systems, moth-proof paper, moth-proof bags and moth-proof glue, as granules or powders for spreading in or on bait.

As already mentioned above, all plants and their parts can be treated according to the invention. In a preferred embodiment, wild plant species and plant cultivars, or those obtained by conventional biological breeding methods, such as crossing or protoplast fusion, and parts thereof, are treated. In another preferred embodiment, the treated plants are transgenic plants and plant cultivars and parts thereof obtained by genetic engineering, such as in combination with conventional breeding methods (Genetic Modified Organisms). The term "parts" or "parts of a plant" or "plant parts" has been explained above.

Particularly preferably plants to be treated according to the invention are those plant cultivars which are respectively commercially available or commonly used. Plant cultivars are understood to mean plants having certain characteristics ("traits") obtained by conventional breeding, mutagenesis or recombinant DNA techniques. They can be varietal, biological- and geographical-type.

Depending on the plant species or plant cultivars, their location and growth conditions (soils, climate, vegetative growth period, fertilizers), the treatment according to the invention can also achieve superadditive (“synergistic”) effects. Thus, for example, it is possible to reduce the application rate and/or expand the active spectrum and/or increase the activity of the active substances and compositions used in the present invention, the growth of the plants is better, the tolerance to high or low temperature is enhanced, and the resistance to drought or flooding is improved. or tolerance to soil salinity, improved flowering, easier harvesting, accelerated maturation, higher yield, better quality and/or harvested products with higher nutritional value, better storage stability and/or Better processability of the harvested product, all of which are beyond what could actually be expected.

(例如玉米，棉花，大豆)，KnockOut(例如玉米)，StarLink

(例如玉米)，Bollgard

(棉花)，Nucotn

(棉花)和NewLeaf

(马铃薯)。可提及的耐除草剂植物的实例是市售的下述玉米品种，棉花品种和大豆品种，它们的商品名为Roundup Ready(耐草甘膦，例如玉米，棉花，大豆)，Liberty Link

(耐膦基麦黄酮，例如油菜)，IMI

(耐咪唑啉酮)以及STS

(耐磺酰脲，例如玉米)。可提及的抗除草剂植物(通过用于除草剂耐受性的常规方法培育的植物)包括商品名为Clearfield

(例如玉米)的市售植物品种。当然，上面的描述也适用于具有这些遗传性状或具有仍需开发的遗传性状的那些植物栽培品种，未来将培育这些植物和/或市场化开发。Transgenic (ie those plants obtained by genetic engineering) plants or plant cultivars which are preferably to be treated according to the invention include all plants which have received genetic material in the genetic modification which imparts particularly useful traits to these plants. Examples of such traits include better growth of plants, increased tolerance to high or low temperatures, increased tolerance to drought or waterlogging or soil salinity, increased flowering rates, easier harvesting, accelerated maturation, Higher yield, better quality and/or higher nutritional value of the harvested product, better storage stability and/or better processing properties of the harvested product. Further and particularly preferred examples of the aforementioned traits are increased defense of plants against animal and microbial pests, such as resistance to insects, mites, phytopathogenic fungi, bacteria and/or viruses, and increased tolerance of plants to certain herbicidally active compounds ability. Examples of transgenic plants that may be mentioned include economically important cereals such as cereals (wheat, rice), maize, soybeans, potatoes, cotton, rapeseed and fruit trees (apples, pears, citrus fruits and grapes), in which particularly preferred Corn, soybeans, potatoes, cotton and canola. Preferred traits increase the plant's defense against insects, in particular through the generation of toxins in the plant, in particular through genetic material derived from Bacillus thuringiensis (e.g. through the genes CryIA(a), CryIA(b), CryIA(c), CryIIA, CryIIIA, CryIIIB2, Cry9c, Cry2Ab, Cry3Bb and CryIF and combinations thereof) (hereinafter referred to as "Bt plants") are those toxins produced in plants. Also particularly preferred traits are increased plant defenses against fungi, bacteria and viruses by systemic acquired resistance (SAR), systemin, phytoalexins, elicitors and resistance genes and correspondingly expressed proteins and toxins. Further particularly preferred traits also include increased plant tolerance to certain herbicidally active compounds, such as imidazolinones, sulfonylureas, glyphosate or phosphinotricoflavones (for example the "PAT" gene). In transgenic plants, the genes imparting the above-mentioned desired traits can also be combined with each other. Examples of "Bt plants" that may be mentioned are the following maize varieties, cotton varieties, soybean varieties and potato varieties commercially available under the trade name YIELDGARD

(e.g. corn, cotton, soybean), KnockOut (e.g. corn), StarLink

(e.g. corn), Bollgard

(Cotton), Nucotn

(cotton) and NewLeaf

(potato). Examples of herbicide-tolerant plants that may be mentioned are the following maize varieties, cotton varieties and soybean varieties commercially available under the trade name Roundup Ready (glyphosate tolerant e.g. corn, cotton, soybeans), Liberty Link

(Phosphin-tolerant Triflavone, e.g. canola), IMI

(imidazolinone resistant) and STS

(resistance to sulfonylureas, such as corn). Herbicide-resistant plants (plants bred by conventional methods for herbicide tolerance) that may be mentioned include the trade name Clearfield

commercially available plant varieties (eg maize). Of course, the above description also applies to those plant cultivars with these genetic traits or with genetic traits still to be developed, which plants will be bred and/or marketed in the future.

The plants mentioned above are treated in a particularly advantageous manner with the active compound mixtures according to the invention by the method according to the invention. The preferred ranges stated above for the active compounds or mixtures according to the invention also apply to the treatment of these plants. Particular preference is given to treating plants with the compounds or mixtures specifically mentioned herein.

Application example

Calculation formula for evaluating the rate of killing from a mixture of two active compounds

The expected activity of a mixture of the two active compounds can be calculated according to the following method (see Colby, SR, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations", Weeds 15 , P20-22, 1967):

if

X The killing rate of active compound A at the application rate of m ppm expressed as a percentage of the untreated control,

The killing rate of Y active compound B at the application rate of n ppm, expressed as a percentage of the untreated control,

E The killing rate of active compounds A and B at the application rate of m and n ppm, expressed as a percentage of the untreated control,

but

$\mathrm{<span\; class="notranslate">\; E.</span>}<span\; class="notranslate">\; =</span>\mathrm{<span\; class="notranslate">\; x</span>}<span\; class="notranslate">\; +</span>\mathrm{<span\; class="notranslate">\; Y</span>}<span\; class="notranslate">\; -</span>\frac{\mathrm{<span\; class="notranslate">\; x</span>}<span\; class="notranslate">\; \&times;</span>\mathrm{<span\; class="notranslate">\; Y</span>}}{\mathrm{<span\; class="notranslate">\; 100</span>}}$

If the actual insecticidal rate exceeds the calculated value, the killing activity of the mixture is superadditive, that is, there is a synergistic effect. In this case, the actual observed kill rate must be greater than the value of the expected kill rate (E) calculated by the above formula.

Example A

Experiment on Phaedon larvae

Solvent: 7 parts by weight dimethylformamide

Emulsifier: 2 parts by weight of alkyl aryl polyglycol ether

To prepare a suitable active compound preparation, 1 part by weight of active compound is mixed with the abovementioned amounts of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier.

Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and then populated with larvae of the Cruciferous beetle (Phaedon cochleariae), while keeping the leaves permanently moist.

)；0％表示没有杀死一头辣根猿叶甲幼虫。测定的致死率是采用Colby公式计算的(见页1)。After a predetermined period of time, the insecticidal activity is determined in %. 100% means that all horseradish beetle larvae have been killed (

); 0% means that no horseradish beetle larvae were killed. The measured lethality was calculated using the Colby formula (see page 1).

In this test, the following active compound mixtures according to the application exhibit a synergistic activity compared to the individual active compounds used alone:

Table A Page 1

insects that infest plants

The larva test of the simian beetle

observed value ^* = observed activity

Calculated value ^** = calculated activity of Colby's formula

Table A Page 2

insects that infest plants

The larva test of the simian beetle

observed value ^* = observed activity

Calculated value ^** = calculated activity of Colby's formula

Example B

Diamondback moth (Plutella) test (common sensitive species)

Solvent: 7 parts by weight dimethylformamide

Emulsifier: 2 parts by weight of alkyl aryl polyglycol ether

To prepare a suitable active compound preparation, 1 part by weight of active compound is mixed with the abovementioned amounts of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier.

Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and then populated with larvae of the common sensitive diamondback moth (Plutellaxylostella), while keeping the leaves permanently moist.

After a predetermined period of time, the insecticidal activity is determined in %. 100% means that all larvae have been killed; 0% means that none of the larvae have been killed. The measured lethality was calculated using the Colby formula (see page 1).

In this test, the following active compound mixtures according to the application exhibit a synergistic activity compared to the individual active compounds used alone:

Form B

Insects infesting plants

Plutella xylostella test (common sensitive species)

observed value ^* = observed activity

Calculated value ^** = calculated activity of Colby's formula

Example C

Plutella xylostella test (resistant population)

Solvent: 7 parts by weight dimethylformamide

Emulsifier: 2 parts by weight of alkyl aryl polyglycol ether

To prepare a suitable active compound preparation, 1 part by weight of active compound is mixed with the abovementioned amounts of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier.

Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and then colonized with resistant diamondback moth larvae while keeping the leaves permanently moist.

After a predetermined period of time, the insecticidal activity is determined in %. 100% means that all larvae have been killed; 0% means that none of the larvae have been killed. The measured lethality was calculated using the Colby formula (see page 1).

In this test, the following active compound mixtures according to the application exhibit a synergistic activity compared to the individual active compounds used alone:

Form C

Insects infesting plants

Plutella xylostella test (resistant population)

observed value ^* = observed activity

Calculated value ^** = calculated activity of Colby's formula

Example D

Lawn armyworm (Spodoptera frugiperda) test

Solvent: 7 parts by weight dimethylformamide

Emulsifier: 2 parts by weight of alkyl aryl polyglycol ether

To prepare a suitable active compound preparation, 1 part by weight of active compound is mixed with the abovementioned amounts of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier.

Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and then populated with larvae of the grass armyworm while keeping the leaves permanently moist.

After a predetermined period of time, the insecticidal activity is determined in %. 100% means that all larvae have been killed; 0% means that none of the larvae have been killed. The measured lethality was calculated using the Colby formula (see page 1).

In this test, the following active compound mixtures according to the application exhibit a synergistic activity compared to the individual active compounds used alone:

Form D

insects that infest plants

Meadow Armyworm Test

observed value ^* = observed activity

Calculated value ^** = calculated activity of Colby's formula

Example E

Experiments with Heliothis virescens

Solvent: dimethylformamide in 7 parts by weight

Emulsifier: 2 parts by weight of alkyl aryl polyglycol ether

To prepare a suitable active compound preparation, 1 part by weight of active compound is mixed with the abovementioned amounts of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier.

Soybean shoots (Glycine max) are treated by being dipped into the preparation of active compound of the desired concentration and then infested with larvae of the tobacco armyworm, while keeping the leaves constantly moist.

After a defined period of time, the insecticidal activity is determined in %. 100% means that all larvae have been killed; 0% means that none of the larvae have been killed. The measured lethality was calculated using the Colby formula (see page 1).

In this test, the following active compound mixtures according to the application exhibit a synergistic activity compared to the individual active compounds used alone:

Form E

insects that infest plants

American tobacco moth test

observed value ^* = observed activity

Calculated value ^** = calculated activity of Colby's formula

Calculation formula for evaluating synergistic activity from a mixture of two active compounds

The expected activity of the mixture of two active compounds can be calculated according to the following method (see Carpenter, C.S., "Mammalian Toxicity of 1-Naphthyl-N-methylcarbamate [Sevin Insecticide]", Agricultural and FoodChemistry, Vol.9, No.1 , pages 30-39, 1961):

if

Pa Proportion of active compound A in the mixture

Proportion of active compound B in Pb mixture

LC _{50 (or 95)} a is the concentration at which 50% (or 95%) of the dead animals are treated with active compound A and

LC _{50 (or 95)} b is the concentration at which 50% (or 95%) of the dead animals are treated with active compound B,

If the calculated LC _{50 (or 95)} value is greater than the measured value and outside the confidence interval (Vertrauensbereichs), the activity of the mixture is superadditive, ie synergistic.

Example A

The larva test of the simian beetle

Solvent: 7 parts by weight dimethylformamide

Emulsifier: 2 parts by weight of alkyl aryl polyglycol ether

To prepare a suitable active compound preparation, 1 part by weight of active compound is mixed with the abovementioned amounts of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier.

Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and then populated with larvae of the Brassicaceae beetle (Brassica oleracea), while keeping the leaves permanently moist.

After a predetermined period of time, the insecticidal activity is determined in %. 100% means that all horseradish beetle larvae have been killed; 0% means that none of the horseradish beetle larvae have been killed. The measured lethality was calculated using the Carpenter formula (see page 1).

In this test, the following mixtures of active compounds of the present application exhibit synergistic activity compared with the prepared active compounds used alone:

Table A

insects that infest plants

The larva test of the simian beetle

observed value ^* = observed activity

Calculated value ^** = calculated activity of Carpenter's formula

Example B

Plutella xylostella test (sensitive species)

Solvent: 7 parts by weight dimethylformamide

Emulsifier: 2 parts by weight of alkyl aryl polyglycol ether

To prepare a suitable active compound preparation, 1 part by weight of active compound is mixed with the abovementioned amounts of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier.

Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and then populated with larvae of diamondback moth (a susceptible species), while keeping the leaves constantly moist.

After a predetermined period of time, the insecticidal activity is determined in %. 100% means that all larvae have been killed; 0% means that none of the larvae have been killed. The measured lethality was calculated using the Carpenter formula (see page 1).

In this test, the following active compound mixtures according to the application exhibit a synergistic activity compared to the individual active compounds used alone:

Form B

insects that infest plants

Plutella xylostella test, sensitive species

observed value ^* = observed activity

Calculated value ^** = calculated activity of Carpenter's formula

Example C

Plutella xylostella test, resistant population

Solvent: 7 parts by weight dimethylformamide

Emulsifier: 2 parts by weight of alkyl aryl polyglycol ether

To prepare a suitable active compound preparation, 1 part by weight of active compound is mixed with the abovementioned amounts of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier.

Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and then populated with larvae of the diamondback moth (resistant population), while keeping the leaves constantly moist.

After a predetermined period of time, the insecticidal activity is determined in %. 100% means that all larvae have been killed; 0% means that none of the larvae have been killed. The measured lethality was calculated using the Carpenter formula (see page 1).

In this test, the following active compound mixtures according to the application exhibit a synergistic activity compared to the individual active compounds used alone:

Form C

Insects infesting plants

Plutella xylostella test, resistant population

observed value ^* = observed activity

Calculated value ^** = calculated activity of Carpenter's formula

Example D

Meadow Armyworm Test

Solvent: 7 parts by weight dimethylformamide

Emulsifier: 2 parts by weight of alkyl aryl polyglycol ether

To prepare a suitable active compound preparation, 1 part by weight of active compound is mixed with the abovementioned amounts of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier.

Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and then populated with larvae of the grass armyworm, while keeping the leaves permanently moist.

After a predetermined period of time, the insecticidal activity is determined in %. 100% means that all larvae have been killed; 0% means that none of the larvae have been killed. The measured lethality was calculated using the Colby formula (see page 1).

In this test, the following active compound mixtures according to the application exhibit a synergistic activity compared to the individual active compounds used alone:

Form D

insects that infest plants

Meadow Armyworm Test

observed value ^* = observed activity

Calculated value ^** = calculated activity of Carpenter's formula

Claims (2)

1. A mixture for controlling animal pests comprising the active compound oxadiazole of the formula

and thiacloprid of formula (IX)

Wherein, the ratio of the oxadiazole and the thiacloprid in parts by weight is 1:1-1:50. 2. the mixture of claim 1 is used for preparing the purposes of the composition that is used for controlling lepidopteran animal pest.