CN100366279C - Method for preparing traditional Chinese medicine to treat apoplexia hemiplegia and said medicine - Google Patents
Method for preparing traditional Chinese medicine to treat apoplexia hemiplegia and said medicine Download PDFInfo
- Publication number
- CN100366279C CN100366279C CNB2006100756940A CN200610075694A CN100366279C CN 100366279 C CN100366279 C CN 100366279C CN B2006100756940 A CNB2006100756940 A CN B2006100756940A CN 200610075694 A CN200610075694 A CN 200610075694A CN 100366279 C CN100366279 C CN 100366279C
- Authority
- CN
- China
- Prior art keywords
- radix
- chinese medicine
- medicine
- blood
- carapax
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 71
- 206010019468 Hemiplegia Diseases 0.000 title claims abstract description 42
- 238000000034 method Methods 0.000 title abstract description 8
- 229940079593 drug Drugs 0.000 claims abstract description 21
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 12
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 12
- 235000008434 ginseng Nutrition 0.000 claims abstract description 12
- 241000489492 Arisaema Species 0.000 claims abstract description 11
- 210000000941 bile Anatomy 0.000 claims abstract description 11
- 241001465754 Metazoa Species 0.000 claims abstract description 10
- 241000196324 Embryophyta Species 0.000 claims abstract description 6
- 238000002360 preparation method Methods 0.000 claims description 17
- 241000271039 Agkistrodon Species 0.000 claims description 11
- 241000208340 Araliaceae Species 0.000 claims description 11
- 241000190633 Cordyceps Species 0.000 claims description 11
- 241001489978 Eupolyphaga Species 0.000 claims description 11
- 241000628997 Flos Species 0.000 claims description 11
- 239000009636 Huang Qi Substances 0.000 claims description 11
- 241000180649 Panax notoginseng Species 0.000 claims description 11
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 11
- 241000237636 Pheretima Species 0.000 claims description 11
- 241000131808 Scolopendra Species 0.000 claims description 11
- 241000522620 Scorpio Species 0.000 claims description 11
- 239000009490 scorpio Substances 0.000 claims description 11
- 241000237903 Hirudo Species 0.000 claims description 9
- 239000002994 raw material Substances 0.000 claims description 5
- 238000005303 weighing Methods 0.000 claims 1
- 239000008280 blood Substances 0.000 abstract description 37
- 210000004369 blood Anatomy 0.000 abstract description 37
- 230000017531 blood circulation Effects 0.000 abstract description 17
- 230000000694 effects Effects 0.000 abstract description 15
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 14
- 201000010099 disease Diseases 0.000 abstract description 13
- 208000006011 Stroke Diseases 0.000 abstract description 7
- 206010008190 Cerebrovascular accident Diseases 0.000 abstract description 6
- 238000005728 strengthening Methods 0.000 abstract description 6
- 210000001519 tissue Anatomy 0.000 abstract description 6
- 210000005036 nerve Anatomy 0.000 abstract description 5
- 230000003387 muscular Effects 0.000 abstract description 4
- 230000005540 biological transmission Effects 0.000 abstract description 3
- 210000004204 blood vessel Anatomy 0.000 abstract description 3
- 210000004958 brain cell Anatomy 0.000 abstract description 3
- 210000003792 cranial nerve Anatomy 0.000 abstract description 3
- 230000000004 hemodynamic effect Effects 0.000 abstract description 3
- 230000001771 impaired effect Effects 0.000 abstract description 3
- 230000035790 physiological processes and functions Effects 0.000 abstract description 3
- 210000002161 motor neuron Anatomy 0.000 abstract description 2
- 244000131316 Panax pseudoginseng Species 0.000 abstract 2
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 241000131329 Carabidae Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 241000258920 Chilopoda Species 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 241000305492 Gastrodia Species 0.000 abstract 1
- 241000545744 Hirudinea Species 0.000 abstract 1
- 241000361919 Metaphire sieboldi Species 0.000 abstract 1
- 241000521581 Millettia Species 0.000 abstract 1
- 240000001307 Myosotis scorpioides Species 0.000 abstract 1
- 235000003181 Panax pseudoginseng Nutrition 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 241000239226 Scorpiones Species 0.000 abstract 1
- 241000270666 Testudines Species 0.000 abstract 1
- 241000270708 Testudinidae Species 0.000 abstract 1
- 241001482963 Thamnophis Species 0.000 abstract 1
- 241000271897 Viperidae Species 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 229940107666 astragalus root Drugs 0.000 abstract 1
- 210000005013 brain tissue Anatomy 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 description 20
- 235000019634 flavors Nutrition 0.000 description 20
- 230000001737 promoting effect Effects 0.000 description 16
- 235000009508 confectionery Nutrition 0.000 description 13
- 210000002435 tendon Anatomy 0.000 description 13
- 210000003414 extremity Anatomy 0.000 description 12
- 230000007812 deficiency Effects 0.000 description 11
- 230000036461 convulsion Effects 0.000 description 10
- 206010010904 Convulsion Diseases 0.000 description 9
- 208000002193 Pain Diseases 0.000 description 8
- 230000001815 facial effect Effects 0.000 description 8
- 210000003205 muscle Anatomy 0.000 description 8
- 208000006820 Arthralgia Diseases 0.000 description 7
- 231100000614 poison Toxicity 0.000 description 7
- 230000007096 poisonous effect Effects 0.000 description 7
- 206010039424 Salivary hypersecretion Diseases 0.000 description 6
- 208000008630 Sialorrhea Diseases 0.000 description 6
- 201000007201 aphasia Diseases 0.000 description 6
- 208000002173 dizziness Diseases 0.000 description 6
- 230000006870 function Effects 0.000 description 6
- 208000019505 Deglutition disease Diseases 0.000 description 5
- 206010062717 Increased upper airway secretion Diseases 0.000 description 5
- 210000003734 kidney Anatomy 0.000 description 5
- 208000026435 phlegm Diseases 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 208000032843 Hemorrhage Diseases 0.000 description 4
- 208000025747 Rheumatic disease Diseases 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 4
- 230000000552 rheumatic effect Effects 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 206010019233 Headaches Diseases 0.000 description 3
- 206010062575 Muscle contracture Diseases 0.000 description 3
- 208000005392 Spasm Diseases 0.000 description 3
- 230000003213 activating effect Effects 0.000 description 3
- 210000001367 artery Anatomy 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 230000002490 cerebral effect Effects 0.000 description 3
- 208000006111 contracture Diseases 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 230000023597 hemostasis Effects 0.000 description 3
- 208000013403 hyperactivity Diseases 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 230000005906 menstruation Effects 0.000 description 3
- 230000002040 relaxant effect Effects 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 2
- 208000015220 Febrile disease Diseases 0.000 description 2
- 206010033799 Paralysis Diseases 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 206010037714 Quadriplegia Diseases 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 238000001467 acupuncture Methods 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000036772 blood pressure Effects 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000000812 cholinergic antagonist Substances 0.000 description 2
- 208000013116 chronic cough Diseases 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 239000002934 diuretic Substances 0.000 description 2
- 230000001882 diuretic effect Effects 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 206010015037 epilepsy Diseases 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 208000021760 high fever Diseases 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 231100000862 numbness Toxicity 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 238000010791 quenching Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000003014 reinforcing effect Effects 0.000 description 2
- 230000002048 spasmolytic effect Effects 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 206010020741 Hyperpyrexia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 244000207740 Lemna minor Species 0.000 description 1
- 235000006439 Lemna minor Nutrition 0.000 description 1
- 241000283956 Manis Species 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 235000001855 Portulaca oleracea Nutrition 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 208000010513 Stupor Diseases 0.000 description 1
- 206010043376 Tetanus Diseases 0.000 description 1
- 208000003217 Tetany Diseases 0.000 description 1
- 208000001435 Thromboembolism Diseases 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000001772 anti-angiogenic effect Effects 0.000 description 1
- 230000001147 anti-toxic effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- -1 as electuary Substances 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000000157 blood function Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 210000000589 cicatrix Anatomy 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 208000013210 hematogenous Diseases 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 210000003701 histiocyte Anatomy 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 201000010849 intracranial embolism Diseases 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002078 massotherapy Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000009418 renovation Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 235000015961 tonic Nutrition 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a method for preparing a traditional Chinese medicine treating apoplexy and hemiplegia, and a traditional Chinese medicine prepared by the method. The method comprises the preparing steps that leech, earthworm, scorpion, long-nosed pit viper, garter snake, tortoise plastron, turtle shell, centipede, ground beetle, stir-baked squama manitis, gastrodia tuber, bile arisaema, safflower, reticulate millettia, astragalus root, ginseng, Chinese angelica, prepared rhizome of rehmannia, pseudo-ginseng and Chinese caterpillar fungus are used as raw medicinal materials; animal medicines and plant medicines are respectively crushed; the crushed animal medicines are decocted and are put into a high-pressure container; the crushed plant medicines are added into the high-pressure container, and the mixed medicine powder are decocted at high temperature. The present invention treats diseases on the basis of overall analyses of patients' conditions, starting with body resistance strengthening, blood nourishment and blood circulation promotion, and consequently, factors causing diseases are eliminated. The medicine can directly relax the blood vessel, can clear the obstruction to hemodynamics, and can regulate the rheological property of blood; the medicine can improve and promote the information transmission among impaired cranial nerve, brain tissues, brain cells, all motor neurons and all muscular tissues, can eliminate focus and can recover various atrophic nerves and atrophic physiological functions of tissues. The medicine has good curative effect, and the total effective rate reaches 100%.
Description
Technical field
The present invention relates to a kind of preparation method of Chinese medicine, relate in particular to a kind of preparation method of Chinese medicine of controlling apoplectic hemiplegia, also relate to Chinese medicine with this method preparation.
Background technology
Apoplexy is global commonly encountered diseases, is brain tremulous pulse or the focal disturbance of blood circulation that causes for the neck arteries pathological changes of cerebral blood supply, thereby causes acute or subacute cerebral lesion, and cardinal symptom is hemiplegia aphasia and stupor.Prevention of stroke, eliminating apoplexy sequela-hemiplegia is one of important subject of current medical circle.Treat hemiplegia at present clinically and use Western medicine vasodilation regulator, neurocyte renovation agent, blood anticoagulant or the traditional Chinese medical science, Chinese medicine, acupuncture, massage therapy usually.Though above-mentioned Western medicine preparation can be played a role to the short apoplectic hemiplegia of some courses of disease, long apoplectic hemiplegia of some courses of disease or the hemiplegia that formed muscle joint shrinkage deformation are not played much effects.Acupuncture, massage, massage be a kind of topical therapeutic also be a kind of auxiliary treatment.Common traditional Chinese medical herbal treatment because the not enough system of medication and simple Chinese herbal medicine great majority are water solublity, are difficult for being absorbed by when injected organism tissue, is difficult to arrive hemiplegia focus core and cell the inside and goes, so therapeutic effect is not obvious.And the formation cause of disease of hemiplegia be numerous and diverse, changeable, both can be cerebrovascular disease, it can be again the hemodynamics obstacle, or other factors causes rupture of blood vessel in brain or thromboembolism and makes brain cell, cranial nerve impaired etc., so must Synergistic treatment, the just effect that can obtain in treatment clinical course.
Summary of the invention
The purpose of this invention is to provide a kind of preparation method of Chinese medicine of apoplectic hemiplegia and Chinese medicine for preparing with this method controlled.The Chinese medicine that the system each side method that adopts the present invention to control the Chinese medicine of apoplectic hemiplegia prepares is vasodilator, removing hemodynamics obstacle, the degeneration of adjusting ware liquid stream directly, can improve and promote again between impaired cranial nerve, cerebral tissue, brain cell and each motor neuron and each muscular tissue the information transmission, eliminate focus, recover the physiological function of various withered exhausted nerve or tissues, effectively the treatment apoplectic hemiplegia has overcome the deficiency that present treatment apoplectic hemiplegia exists.
The present invention controls the preparation method of Chinese medicine of apoplectic hemiplegia, and its step is as follows:
1. crude drug and weight proportion thereof are:
Hirudo 4-10g, Pheretima 8-15g, Scorpio 4-8g, Agkistrodon 8-15g,
Zaocys 8-15g, Carapax et Plastrum Testudinis 10-18g, Carapax Trionycis 10-18g, Scolopendra 1.5-4g,
Eupolyphaga Seu Steleophaga 6-15g, stir-baked SQUAMA MANITIS 8-15g, Rhizoma Gastrodiae 8-15g, Arisaema Cum Bile 8-14g,
Flos Carthami 6-15g, Caulis Spatholobi 10-25g, Radix Astragali 12-35g, Radix Ginseng 6-15g,
Radix Angelicae Sinensis 8-15g, Radix Rehmanniae Preparata 10-20g, Radix Notoginseng 6-13g, Cordyceps 6-12g;
Crude drug and preferred weight proportioning thereof are:
Hirudo 4-7g, Pheretima 8-11g, Scorpio 4-6g, Agkistrodon 10-15g,
Zaocys 10-15g, Carapax et Plastrum Testudinis 15-18g, Carapax Trionycis 10-13g, Scolopendra 2.5-4g
Eupolyphaga Seu Steleophaga 6-10g stir-baked SQUAMA MANITIS 8-12g, Rhizoma Gastrodiae 11-15g, Arisaema Cum Bile 8-12g,
Flos Carthami 8-15g, Caulis Spatholobi 15-25g, Radix Astragali 20-35g, Radix Ginseng 8-15g,
Radix Angelicae Sinensis 8-13g, Radix Rehmanniae Preparata 15-20g, Radix Notoginseng 6-10g, Cordyceps 8-12g.
With the animal class crude drug-Hirudo in the required above-mentioned raw materials medicine, Pheretima, Scorpio, Agkistrodon, Zaocys, Carapax et Plastrum Testudinis, Carapax Trionycis, Scolopendra, Eupolyphaga Seu Steleophaga, stir-baked SQUAMA MANITIS, and plant class crude drug-Rhizoma Gastrodiae, Arisaema Cum Bile, Flos Carthami, Caulis Spatholobi, the Radix Astragali, Radix Ginseng, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Radix Notoginseng, Cordyceps pulverize with pulverizer respectively;
3. the above-mentioned animal class crude drug of having pulverized was decocted 30 minutes, put into high-pressure bottle again;
4. the above-mentioned class of comminuted plants crude drug is put into above-mentioned high-pressure bottle, be heated to 120 ℃, decocted again 15 minutes, filter, obtain the Chinese medicine of decoction-treatment apoplectic hemiplegia.
The present invention controls the instructions of taking of the Chinese medicine of apoplectic hemiplegia: one pair of every day, one day twice; General 15-20 days is a course of treatment.
Control the Chinese medicine of the preparation method of Chinese medicine preparation of apoplectic hemiplegia by the present invention, also can make common dosage form, as electuary, tablet, oral liquid, honeyed pill, the watered pill, capsule etc. by the pharmaceutics common method.
The present invention is based on some strong toxicities, have very strong active animal drugs to human nerve, blood vessel, blood, cell, selection has blood circulation promoting and blood stasis dispelling, the animal of the sharp key of promoting blood circulation, relaxing muscles and tendons and activating QI and blood in the collateral, elimination paralysis effect is used as medicine, utilize these medicines strong to the human body zest, excited and those long periods of activation lose the nerve and the histiocyte of information transmission and forfeiture normal physiological function.The stimulation excitation of the lubricant component institute tool of animal simultaneously and with the meeting property of focus cell membrane, make it can directly arrive the focus core and focus is removed in the cell the inside.Be aided with simultaneously have qi-supplementing, blood-engendering, nourishing blood and promoting granulation, promoting the circulation of blood hemostasis, blood circulation promoting and blood stasis dispelling, Shujin are promoted blood circulation, the Conclusion Decreasing blood stasis dispelling, remove the Chinese crude drug of hemiplegia effect, reach strengthening the body resistance, eliminating evil and just do not hinder, set upright and do not stay heresy, blood circulation promoting and blood stasis dispelling collateral dredging and do not cause new hemorrhage purpose, effectively treat various apoplectic hemiplegia.
Hirudo: nature and flavor are salty, and are flat, slightly poisonous, have removing blood stasis, anti-angiogenic, the blood circulation promoting effect.
Pheretima: nature and flavor are salty, the heat clearing away relieving convulsion, and active blood stasis dispelling, salty-cold, property is apt to away scurry, inducing menstruation to relieve menalgia, and energy clearing away heat and relieving the wind syndrome, arresting convulsion, the diuretic of relievining asthma.Have the various epidemic febrile disease of treatment, hyperpyrexia, agitation is twitched, and it is unfavorable that the limbs song is stretched, and hemiplegia and accumulation of heat urine retention are panted etc.
Scorpio: nature and flavor are flat, and are sweet, and suffering is poisonous, the spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.Sweet, suffering, poisonous, be longer than relieving spasm by subduing liver-wind, removing obstruction in the collateral to relieve pain is controlled infantile convulsion and is twitched, and tetanus, apoplexy facial hemiparalysis are the analgesic key medicine of expellingging wind and relieving convulsion.
Carapax et Plastrum Testudinis: nature and flavor are cold, salty, sweet, nourishing YIN and benefiting blood, the kidney tonifying YANG hyperactivity suppressing, bone strengthening is sweet salty and cold, kind nourishing YIN branch can YIN nourishing and the heart-fire clearind deficient heat falls in YANG hyperactivity suppressing, nourish blood, and can only collapse by controlling nocturnal emission with astringent drugs, reinforcing the heart, the kidney invigorating are arranged, enrich blood, be the key medicine of nourishing YIN and benefiting blood, clearind deficient heat, and the strengthening by means of tonics effect is arranged, the bone strengthening Conclusion Decreasing is used for cloudy the having a dizzy spell of hyperactivity of fire of losing, the diseases such as soft blood deficiency metrorrhagia of withering of tetany, the insufficient muscles and bones of suffering from a deficiency of the kidney due to cardiopalmus tinnitus and the consumption of body fluid caused by febrile disease.
Carapax Trionycis: nature and flavor are cold, and are salty, nourishing YIN for suppressing the hyperactive YANG, and hard masses softening and resolving is salty-coldly gone into blood, can nourishing YIN and clearing away heat, can dive again and fall floating sun, but and hard masses softening and resolving, be deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, the key medicine of blood stasis Tian Jia.
Scolopendra: the nature and flavor suffering, temperature, poisonous, have the spasmolytic of relieving dizziness, high fever, infantile convulsions, epilepsy, etc., detoxicating and resolving stagnation of pathogens, removing obstruction in the collateral to relieve pain effect.Cure mainly spasm and twitch, intractable headache is taken out the pain of pulling, and diseases such as rheumatic arthralgia have good inducing menstruation to relieve menalgia effect.
Eupolyphaga Seu Steleophaga: nature and flavor are salty, and are cold, slightly poisonous, the energy removing blood stasis, and reunion of fractured tendons and bones has active arthralgia aggravated by cold, the merit of the pain relieving of curing the wound.
Stir-baked SQUAMA MANITIS: nature and flavor are salty, are slightly cold effect energy promoting blood circulation to remove obstruction in the collateral stimulating milk secretion, detumescence and apocenosis.Squama Manis is good at walking to scurry, and property is specially done good works, can collateral dredging and reach disease institute, be used for the treatment of amenorrhea due to stagnation of blood cicatrix mass in the abdomen, and rheumatic arthralgia, the limbs contracture is tetanic to wait disease.
Agkistrodon: nature and flavor, sweet, salty, temperature, poisonous, have strong dispelling, collateral-activating, arresting convulsion function, cure mainly rheumatalgia, the contracture of muscle arteries and veins, facial hemiparalysis, numb limbs and tense tendons, the unsuccessful effect of apoplexy lower body.
Zaocys: nature and flavor are sweet, and are flat, nontoxic, can calm the frightened by dispelling, collateral-activating, cure mainly rheumatic arthralgia, the contracture of muscle arteries and veins, and numb limbs and tense tendons, the apoplexy lower body is unsuccessful.
Rhizoma Gastrodiae: nature and flavor are sweet, and are flat, have relieving spasm by subduing liver-wind, the suppressing the hyperactive liver and subsiding YANG function.The treatment liver-wind stirring up internally is arranged, and infantile convulsion is twitched, wind-damp dispelling, stopping numbness pain, the dizziness headache of excessive rising of liver-YANG and numb limbs and tense tendons, hands and feet caused by paralysis effect.
Rhizoma Arisaematis: the nature and flavor hardship, suffering, temperature, poisonous, have only drying dampness to eliminate phlegm, the collateral dredging function of expellingging wind and relieving convulsion.There is treatment phlegm-damp harmony to stagnate, dizziness due to wind-phlegm, middle wind-phlegm harmony, mouthful eye whirlpool is oblique, the rheumatism stupid fiber crops of brothers that meridians cause of being detained, hemiplegia effect.
Flos Carthami: nature and flavor, suffering, temperature has blood circulation promoting and blood stasis dispelling, the function of stimulating the menstrual flow, the merit of this product blood circulation promoting and blood stasis dispelling is excellent, is widely used in the disease of the multiple congestion retardance of clinical each section for trouble or hematogenous blockage in recent years.Key medicine for apoplectic hemiplegia.
Caulis Spatholobi: the nature and flavor hardship, little sweet, temperature has promoting the circulation of blood and enriches blood, and relaxing muscles and tendons and activating QI and blood in the collateral can be enriched blood, and can invigorate blood circulation again, has the merit of relaxing muscles and tendons and activating QI and blood in the collateral, and the treatment arthralgia is arranged, numb hand and foot, quadriplegia, rheumatic arthralgia.
Radix Ginseng: nature and flavor are sweet, little hardship, and tepor has strongly invigorating primordial QI, the spleen reinforcing the liver benefiting, promoting the production of body fluid to quench thirst, calming the nerves increases the intelligence function.Control the deficiency of vital energy, anemia, the deficiency of vital energy are desired to take off, deficiency of spleen-QI, and lung qi loses empty, the effect that Tianjin wound is thirsty.
The Radix Astragali: nature and flavor are sweet, and tepor, tonifying Qi and lifting yang, benefit are defended consolidating superficial resistance, antitoxin granulation promoting, diuretic detumescent, have the treatment asthenia of pulmonosplenic qi, sinking of QI of middle-JIAO, and blood stagnancy due to deficiency of QI causes numb limbs and tense tendons, arthralgia, hemiplegia, the disease such as quench one's thirst of deficiency of vital energy body fluid deficiency.
Radix Angelicae Sinensis: nature and flavor, temperature, sweet, suffering, hardship has and enriches blood, invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation can nourishing blood for regulating menstruation, again can promoting blood circulation and stopping pain, have the Wen Erneng profit, mend and oiliness effect.
Radix Rehmanniae Preparata: the nature and flavor temperature, sweet in the mouth has liver and kidney tonifying, the nourishing YIN and benefiting blood function.
Radix Notoginseng: nature and flavor are sweet, little hardship, temperature.Can removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation is used for the inside and outside various hemorrhage diseases of human body, can blood circulation promoting and blood stasis dispelling, have the advantages that the stasis of blood is not stayed in hemostasis, to have the stasis of blood person that stagnates concurrently particularly suitable to hemorrhage.
Cordyceps: nature and flavor, Gan Wen, but but not only kidney tonifying nourishing YIN but also tonification lung yin, hemostasis and phlegm.The treatment impotence and seminal emission, soreness of waist and knee joint, chronic cough dyspnea due to deficiency, chronic cough expectorant blood, and multiple or spontaneous perspiration fear of cold of body void or the like after being ill.
Can cause aphasia, facial hemiparalysis, sialorrhea, dysphagia, numb limbs and tense tendons, joint stuffiness behind the apoplectic hemiplegia.The present invention has selected the principal agent of animal drugs as the treatment apoplectic hemiplegia for use, starts with from strengthening the body resistance, nourshing blood and promoting blood circulation simultaneously, comprehensive determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs,, thereby elimination paathogenic factor, regulate the function of each system of human body comprehensively, strengthen human body stress and tolerance, so therapeutic effect is good.Apoplectic hemiplegia patient majority is taken promptly has positive effect in 1-2 week, and it is normal that blood pressure recovers, and muscle power strengthens, spirit takes a turn for the better, muscular strength improves, and numbness of hands and feet, headache and dizzy phenomenon are eliminated facial hemiparalysis, the quadriplegia phenomenon is obviously improved, continue to take, health recovers normally gradually, obtains recovery from illness, cure rate is 90%, and total effective rate reaches 100%.
Raw material required for the present invention, equipment all have commercially available.
The specific embodiment
Embodiment 1
Control the Chinese medicine of apoplectic hemiplegia by above-mentioned preparation method preparation, the first step wherein, the component of crude drug and weight proportion thereof are: Hirudo 4g, Pheretima 8g, Scorpio 4g, Agkistrodon 8g, Zaocys 8g, Carapax et Plastrum Testudinis 10g, Carapax Trionycis 10g, Scolopendra 1.5g, Eupolyphaga Seu Steleophaga 6g, stir-baked SQUAMA MANITIS 8g, Rhizoma Gastrodiae 8g, Arisaema Cum Bile 8g, Flos Carthami 6g, Caulis Spatholobi 10g, Radix Astragali 12g, Radix Ginseng 6g, Radix Angelicae Sinensis 8g, Radix Rehmanniae Preparata 10g, Radix Notoginseng 6g, Cordyceps 6g.
Embodiment 2
Control the Chinese medicine of apoplectic hemiplegia by above-mentioned preparation method preparation, the first step wherein, the component of crude drug and weight proportion thereof are: Hirudo 7g, Pheretima 11g, Scorpio 6g, Agkistrodon 10g, Zaocys 10g, Carapax et Plastrum Testudinis 15g, Carapax Trionycis 13g, Scolopendra 2.5g, Eupolyphaga Seu Steleophaga 10g, stir-baked SQUAMA MANITIS 12g, Rhizoma Gastrodiae 11g, Arisaema Cum Bile 12g, Flos Carthami 8g, Caulis Spatholobi 15g, Radix Astragali 20g, Radix Ginseng 8g, Radix Angelicae Sinensis 13g, Radix Rehmanniae Preparata 15g, Radix Notoginseng 10g, Cordyceps 8g.
Embodiment 3
Control the Chinese medicine of apoplectic hemiplegia by above-mentioned preparation method preparation, the first step wherein, the component of crude drug and weight proportion thereof are: Hirudo 10g, Pheretima 15g, Scorpio 8g, Agkistrodon 15g, Zaocys 15g, Carapax et Plastrum Testudinis 18g, Carapax Trionycis 18g, Scolopendra 4g, Eupolyphaga Seu Steleophaga 15g, stir-baked SQUAMA MANITIS 15g, Rhizoma Gastrodiae 15g, Arisaema Cum Bile 14g, Flos Carthami 15g, Caulis Spatholobi 25g, Radix Astragali 35g, Radix Ginseng 15g, Radix Angelicae Sinensis 15g, Radix Rehmanniae Preparata 20g, Radix Notoginseng 13g, Cordyceps 12g.
Clinical observation is summed up
One. the diagnostic criteria of apoplectic hemiplegia: hypertension, aphasia, facial hemiparalysis, sialorrhea, dysphagia, numb limbs and tense tendons, joint stuffiness etc.
Two. control the instructions of taking of the Chinese medicine of apoplectic hemiplegia: one pair of every day, one day twice; General 15-20 days is a course of treatment.
Three. efficacy assessment standard:
1. cure: blood pressure recovers normal, and spirit takes a turn for the better, and muscular strength improves, clinical symptom disappearance such as aphasia, facial hemiparalysis, sialorrhea, dysphagia, numb limbs and tense tendons, joint stuffiness.
2. effective: clinical symptom relief, obviously improve as phenomenons such as aphasia, facial hemiparalysis, sialorrhea, dysphagia, numb limbs and tense tendons, joint stuffiness.
Four. therapeutic effect: clinical observation is totally 100 examples, wherein male 64 examples, women 36 examples; Cure 92 examples, cure rate reaches 92%; Effective 8 examples, total effective rate reaches 100%.
Model case
1. Ma Gang, man, 61 years old; Apoplectic hemiplegia more than 8 years, in so for many years, has been walked a lot of hospitals, Chinese medicine, medical herbs, Western medicine, massage, and the washout Chinese herbal medicine is all constantly using.In the past two years, lower limb are atrophy, and it is active in bed to sleep, and defecation also is in bed.The present invention who opened two courses of treatment (40 days) last year controls the Chinese medicine of apoplectic hemiplegia, after taking, can walk now, and life also can have been taken care of oneself.
2. Liu Changping, man, 63 years old; Suffering from apoplectic hemiplegia has had for many years, his symptom is exactly sialorrhea, dysphagia, numb limbs and tense tendons, and Chinese medicine and western medicine was all used, and is exactly ineffective, the present invention who had eaten two courses of treatment (40 days) afterwards controls the Chinese medicine of apoplectic hemiplegia, be clearly better, can have a meal very smoothly, extremity have also had consciousness, can loose, after continuing to have taken a course of treatment again, can freely loose, spirit might as well.
3. open duckweed, woman, 54 years old; Cause symptoms such as aphasia, facial hemiparalysis, sialorrhea behind the apoplectic hemiplegia,, used a lot of medicines, all do not have effect to a lot of hospitalizes.Ate the present invention afterwards and control two courses of treatment of Chinese medicine decoction (30 days) of apoplectic hemiplegia, the state of an illness takes a turn for the better to some extent, mouthful eye recovery gradually normal, after taken two courses of treatment again, disease has disappeared, and just recurs never again later on.
Claims (4)
1. a Chinese medicine decoction for the treatment of apoplectic hemiplegia is characterized in that, prepares its raw materials of effective components medicine and weight ratio thereof to be:
Hirudo 4-10g, Pheretima 8-15g, Scorpio 4-8g, Agkistrodon 8-15g,
Zaocys 8-15g, Carapax et Plastrum Testudinis 10-18g, Carapax Trionycis 10-18g, Scolopendra 1.5-4g,
Eupolyphaga Seu Steleophaga 6-15g, stir-baked SQUAMA MANITIS 8-15g, Rhizoma Gastrodiae 8-15g, Arisaema Cum Bile 8-14g,
Flos Carthami 6-15g, Caulis Spatholobi 10-25g, Radix Astragali 12-35g, Radix Ginseng 6-15g,
Radix Angelicae Sinensis 8-15g, Radix Rehmanniae Preparata 10-20g, Radix Notoginseng 6-13g, Cordyceps 6-12g.
2. Chinese medicine decoction as claimed in claim 1 is characterized in that, prepares its raw materials of effective components medicine and weight ratio thereof to be:
Hirudo 4-7g, Pheretima 8-11g, Scorpio 4-6g, Agkistrodon 10-15g,
Zaocys 10-15g, Carapax et Plastrum Testudinis 15-18g, Carapax Trionycis 10-13g, Scolopendra 2.5-4g
Eupolyphaga Seu Steleophaga 6-10g stir-baked SQUAMA MANITIS 8-12g, Rhizoma Gastrodiae 11-15g, Arisaema Cum Bile 8-12g,
Flos Carthami 8-15g, Caulis Spatholobi 15-25g, Radix Astragali 20-35g, Radix Ginseng 8-15g,
Radix Angelicae Sinensis 8-13g, Radix Rehmanniae Preparata 15-20g, Radix Notoginseng 6-10g, Cordyceps 8-12g.
3. Chinese medicine decoction as claimed in claim 1, it is characterized in that, prepare its raw materials of effective components medicine and weight ratio thereof and be: Hirudo 10g, Pheretima 15g, Scorpio 8g, Agkistrodon 15g, Zaocys 15g, Carapax et Plastrum Testudinis 18g, Carapax Trionycis 18g, Scolopendra 4g, Eupolyphaga Seu Steleophaga 15g, stir-baked SQUAMA MANITIS 15g, Rhizoma Gastrodiae 15g, Arisaema Cum Bile 14g Flos Carthami 15g, Caulis Spatholobi 25g, Radix Astragali 35g, Radix Ginseng 15g, Radix Angelicae Sinensis 15g, Radix Rehmanniae Preparata 20g, Radix Notoginseng 13g, Cordyceps 12g.
4. as the preparation method of each described Chinese medicine decoction among the claim 1-3, it is characterized in that making by following step:
1) takes by weighing each crude drug according to its weight ratio, and animal class crude drug-Hirudo, Pheretima, Scorpio, Agkistrodon, Zaocys, Carapax et Plastrum Testudinis, Carapax Trionycis, Scolopendra, Eupolyphaga Seu Steleophaga, stir-baked SQUAMA MANITIS are pulverized with pulverizer; Plant class crude drug-Rhizoma Gastrodiae, Arisaema Cum Bile, Flos Carthami, Caulis Spatholobi, the Radix Astragali, Radix Ginseng, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Radix Notoginseng, Cordyceps are also pulverized with pulverizer;
2) the above-mentioned animal class crude drug of having pulverized was decocted 30 minutes, put into high-pressure bottle again;
3) the above-mentioned class of comminuted plants crude drug is put into above-mentioned high-pressure bottle, and be heated to 120 ℃, decocted again 15 minutes, filter the Chinese medicine decoction of the apoplectic hemiplegia that obtains medical treatment.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2006100756940A CN100366279C (en) | 2006-04-18 | 2006-04-18 | Method for preparing traditional Chinese medicine to treat apoplexia hemiplegia and said medicine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2006100756940A CN100366279C (en) | 2006-04-18 | 2006-04-18 | Method for preparing traditional Chinese medicine to treat apoplexia hemiplegia and said medicine |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1861171A CN1861171A (en) | 2006-11-15 |
CN100366279C true CN100366279C (en) | 2008-02-06 |
Family
ID=37388757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2006100756940A Expired - Fee Related CN100366279C (en) | 2006-04-18 | 2006-04-18 | Method for preparing traditional Chinese medicine to treat apoplexia hemiplegia and said medicine |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN100366279C (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101628054B (en) * | 2009-08-02 | 2011-08-31 | 李述岩 | Medicine for treating ischemic stroke and sequela thereof |
CN103494953B (en) * | 2013-10-15 | 2015-11-11 | 杨逢贤 | Purify the blood capsule and preparation method thereof |
CN104127643A (en) * | 2014-07-21 | 2014-11-05 | 刘远杰 | Medicament for treatment of cerebral apoplexy and preparation method thereof |
CN105169265A (en) * | 2015-09-30 | 2015-12-23 | 青岛友诚高新技术有限公司 | Traditional Chinese medicine composition for treating hemiplegia and preparation method of traditional Chinese medicine composition |
CN105770498B (en) * | 2016-04-13 | 2019-10-18 | 河南省傅潭酒业有限公司 | A kind of traditional Chinese medicine wine for treating hemiplegia after ischemic cerebral apoplexy and its preparation method |
CN105770758A (en) * | 2016-04-22 | 2016-07-20 | 涂已文 | Drug for treating stroke paralysis |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1106674A (en) * | 1994-10-13 | 1995-08-16 | 汪志伟 | Traditional Chinese medicine for curing paralysis |
CN1660395A (en) * | 2004-12-27 | 2005-08-31 | 杨俭 | Formula of treating apoplexy |
CN1686510A (en) * | 2005-04-14 | 2005-10-26 | 赵宏伟 | Ready prepared Chinese medicine for preventing and treating brain apoplexia |
-
2006
- 2006-04-18 CN CNB2006100756940A patent/CN100366279C/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1106674A (en) * | 1994-10-13 | 1995-08-16 | 汪志伟 | Traditional Chinese medicine for curing paralysis |
CN1660395A (en) * | 2004-12-27 | 2005-08-31 | 杨俭 | Formula of treating apoplexy |
CN1686510A (en) * | 2005-04-14 | 2005-10-26 | 赵宏伟 | Ready prepared Chinese medicine for preventing and treating brain apoplexia |
Also Published As
Publication number | Publication date |
---|---|
CN1861171A (en) | 2006-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104958484A (en) | traditional Chinese medicine unguent for promoting blood circulation to remove meridian obstruction and preparing method of traditional Chinese medicine unguent | |
CN103356877A (en) | Traditional Chinese medicine composition for treating orthopedic diseases | |
CN100366279C (en) | Method for preparing traditional Chinese medicine to treat apoplexia hemiplegia and said medicine | |
CN103212045A (en) | Fumigated drug for treating arthralgia | |
CN102119990A (en) | Chinese medicinal preparation for nourishing liver and kidney, supplementing qi, engendering blood, promoting blood circulation, removing obstruction in channels and relieving pain | |
CN100366278C (en) | Method for preparing traditional Chinese medicine for treating rheumatism and rheumatoid disease, and said medicine thereby | |
CN101450197B (en) | Traditional Chinese medicine for treating rheumatism, rheumatoid disease | |
CN102247497A (en) | Chinese patent medicine for treating rheumatoid arthritis | |
CN101690768B (en) | Vein and artery relieving pills for impediment of sinew | |
CN102274457B (en) | Physiotherapy enhanced spray for scraping and massaging | |
CN103446453A (en) | Chinese patent medicine oral capsule for curing pains in necks, shoulders, waists, and legs | |
CN103721082A (en) | Traditional Chinese medicinal composition for treating scapulohumeral periarthritis | |
CN115054674A (en) | Formula and using method of external plaster for relieving pain, softening hardness and dissipating stagnation | |
CN103202985A (en) | Traditional Chinese medicine used for treating lumbar spondylosis, cervical spondylosis, sciatica and rheumatism and preparation method thereof | |
CN102600328B (en) | Fracture setting hot compress traditional Chinese medicine bag | |
CN102512560A (en) | Traditional Chinese medicinal composition for treating arthromyodynia | |
CN101797291B (en) | Traditional Chinese medicine for treating osteoproliferation | |
CN101041021A (en) | Chinese medicines composition took orally for treating vrain apoplexy | |
CN101194985B (en) | Orally taken Chinese medicine composition for treating articulatio genus hyperosteogeny | |
CN105250933B (en) | A kind of preparation method of the 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots and its paste | |
CN103610914B (en) | A kind of internal traditional Chinese medicinal wine for the treatment of rheumatic arthritis | |
CN102028810B (en) | Traditional Chinese medicine for treating lumbar intervertebral disc protrusion | |
CN102397422A (en) | Chinese herbal medicine preparation for treating ischemic necrosis of femoral head | |
CN102512543A (en) | Chinese medicinal composition for treating rheumatoid arthritis | |
CN106344793A (en) | Traditional Chinese medicine foot bath powder for treating arthritis and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080206 Termination date: 20100418 |