CN100350943C - Medicinal composition for treating hepatitis B and preparation method thereof - Google Patents
Medicinal composition for treating hepatitis B and preparation method thereof Download PDFInfo
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- CN100350943C CN100350943C CNB2004100677013A CN200410067701A CN100350943C CN 100350943 C CN100350943 C CN 100350943C CN B2004100677013 A CNB2004100677013 A CN B2004100677013A CN 200410067701 A CN200410067701 A CN 200410067701A CN 100350943 C CN100350943 C CN 100350943C
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- hepatitis
- radix
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- herba
- roots
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- 208000002672 hepatitis B Diseases 0.000 title claims abstract description 27
- 239000000203 mixture Substances 0.000 title claims abstract description 8
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 239000000843 powder Substances 0.000 claims abstract description 28
- 239000007788 liquid Substances 0.000 claims abstract description 23
- 239000002994 raw material Substances 0.000 claims abstract description 8
- 238000000034 method Methods 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims description 16
- 241000756943 Codonopsis Species 0.000 claims description 13
- 241001252483 Kalimeris Species 0.000 claims description 13
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 13
- 239000009636 Huang Qi Substances 0.000 claims description 11
- 241000545442 Radix Species 0.000 claims description 8
- 238000012856 packing Methods 0.000 claims description 7
- 239000008194 pharmaceutical composition Substances 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 5
- 239000012535 impurity Substances 0.000 claims description 5
- 230000002262 irrigation Effects 0.000 claims description 5
- 238000003973 irrigation Methods 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 229940079593 drug Drugs 0.000 claims description 3
- 230000017531 blood circulation Effects 0.000 abstract description 6
- 239000008280 blood Substances 0.000 abstract description 5
- 210000004369 blood Anatomy 0.000 abstract description 5
- 230000036737 immune function Effects 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 3
- 230000006870 function Effects 0.000 abstract description 3
- 241000700721 Hepatitis B virus Species 0.000 abstract description 2
- 210000004185 liver Anatomy 0.000 abstract description 2
- 230000003908 liver function Effects 0.000 abstract description 2
- 230000008030 elimination Effects 0.000 abstract 2
- 238000003379 elimination reaction Methods 0.000 abstract 2
- 241001061264 Astragalus Species 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 241000050051 Chelone glabra Species 0.000 abstract 1
- 241000729173 Cirsium japonicum Species 0.000 abstract 1
- 241000594402 Damnacanthus Species 0.000 abstract 1
- 241000756137 Hemerocallis Species 0.000 abstract 1
- 240000001659 Oldenlandia diffusa Species 0.000 abstract 1
- 244000248825 Peltandra virginica Species 0.000 abstract 1
- 235000001188 Peltandra virginica Nutrition 0.000 abstract 1
- 241000985694 Polypodiopsida Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 241000593775 Serissa Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 235000008216 herbs Nutrition 0.000 abstract 1
- 210000005229 liver cell Anatomy 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 210000000582 semen Anatomy 0.000 abstract 1
- 210000004233 talus Anatomy 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 231100000283 hepatitis Toxicity 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 206010003445 Ascites Diseases 0.000 description 1
- 206010008909 Chronic Hepatitis Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 210000003494 hepatocyte Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a medicinal composition for treating hepatitis B and a preparation method thereof. The preparation method comprises: preparing hepatitis B negative turning liquid by using astragalus roots, pilose asiabell roots, asket ferns, tuckahoe, white atractylodes rhizomes, barbat skullcap, damnacanthus, serissa herbs, oldenlandia diffusa, day-lily flower roots and semen coicis roots as raw materials; preparing hepatitis B negative turning powder by using cirsium japonicum roots and malan roots as raw materials; separately packaging the hepatitis B negative turning liquid and the hepatitis B negative turning powder; then obtaining the medicinal composition by putting the hepatitis B negative turning liquid and the hepatitis B negative turning powder together. The combination of the hepatitis B negative turning liquid and the hepatitis B negative turning powder of the medicinal composition can effectively regulate various functions in bodies, participate the killing and the elimination of hepatitis B viruses, purify blood, improve liver blood circulation, protect liver cells and restore liver functions. The hepatitis B can be fundamentally cured. The taking method of the medical combination is: the hepatitis B negative turning liquid is taken by twice per day, once in the morning, the other once in the afternoon; the hepatitis B negative turning powder is taken by once in the morning, and the other once in the afternoon, each time is 4g. Thus, the present invention has the advantages of dampness elimination, stasis transformation, blood circulation promotion, high curing rate, no recurrence after turning negative, no toxic and side function and outstanding curing effect. The immune function of hepatitis B patients can be strengthened.
Description
Technical field
What the present invention relates to is medicine in the field of medicaments, especially relates to a kind of pharmaceutical composition for the treatment of hepatitis B and preparation method thereof.
Background technology
Hepatitis is a kind of infectious disease, divide first, second, third, fourth, penta, oneself, 7 kinds of heptan, because it is popular extensively, hazardness is big, sickness rate is high, being one of difficult and complicated illness of generally acknowledging both at home and abroad at present, is example with the hepatitis B, and just there is hepatitis B (being commonly called as big and small three Yang) patient nearly 50,000,000 in light China, annual newly-increased patient about 1,100,000, cure rate is 10% only, and the overwhelming majority transfers chronic hepatitis to, serious hepatic ascites, the hepatocarcinoma of being converted into.The drug variety for the treatment of hepatitis at present clinically is very many, but there are long, shortcomings such as negative conversion rate is low, meeting bounce-back medicine time in most of medicine, and some medicine also has significant side effects, and the harm people's is healthy.
Summary of the invention
The purpose of this invention is to provide a kind ofly can strengthen that hepatitis B patient immunologic function, damp eliminating blood stasis dispelling are invigorated blood circulation, the pharmaceutical composition of clearing away heat-damp and promoting diuresis detoxifcation, cure rate height, the treatment hepatitis B that do not rebound, have no side effect after turning out cloudy and preparation method thereof.
The object of the present invention is achieved like this: the present invention is made up of medicinal liquid and two kinds of medicines of medicated powder:
(1), medicinal liquid: form by following raw material in weight portion:
The Radix Astragali 50 Herba Scutellariae Barbataes 15 Herba Hedyotidis Diffusaes 13 Radix Codonopsis 7
Rhizoma Osmundae 8 Herba Damnacanthi 20 hemerocallitis,radixs 40 Poria 6
The Rhizoma Atractylodis Macrocephalae 18 Radix Serissae 24 italian-jobi jen roots 50;
(2), medicated powder: form by following two kinds of raw materials in weight portion:
Cirsii japonici,radix 10 root of Indian kalimeris herb 15.
Preparation method of the present invention is:
1, the Radix Astragali, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Radix Codonopsis, Rhizoma Osmundae, Herba Damnacanthi, hemerocallitis,radix, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Serissae, italian-jobi jen root, cirsii japonici,radix and root of Indian kalimeris herb are cleaned respectively, remove impurity, be up to the standards;
50 parts of Radixs Astragali that 2, will be up to the standards, 15 portions of Herba Scutellariae Barbataes, 13 parts of Herba Hedyotidis Diffusaes, 7 parts of Radix Codonopsis, 8 parts of Rhizoma Osmundae, 20 parts of Herba Damnacanthi, 40 parts of hemerocallitis,radixs, 6 parts of Poria, 18 parts of Rhizoma Atractylodis Macrocephalaes, 24 parts of Radix Serissae and 50 parts of italian-jobi jen roots mix puts into medicinal cupping, decoct with water, obtain medicinal liquid after the filtration;
10 parts of cirsii japonici,radixs that 3, will be up to the standards and 15 parts of root of Indian kalimeris herb mix the back and are ground into powder with pulverizer, obtain medicated powder;
4, medicine liquid irrigation is packed into bottle, with the medicated powder branch pouch of packing into, closing puts together again gets product.
The present invention is to be that raw material is made medicinal liquid with the Radix Astragali, Radix Codonopsis, Rhizoma Osmundae, Poria, the Rhizoma Atractylodis Macrocephalae, Herba Scutellariae Barbatae, Herba Damnacanthi, Radix Serissae, Herba Hedyotidis Diffusae, hemerocallitis,radix, italian-jobi jen root, be that raw material is made medicated powder with cirsii japonici,radix and root of Indian kalimeris herb again, close again to put together and promptly get pharmaceutical composition after the packing respectively.Medicinal liquid in the pharmaceutical composition of the present invention can detoxify by clearing away heat-damp and promoting diuresis; can strengthen the hepatitis B patient immunologic function; medicated powder can be invigorated blood circulation in the damp eliminating blood stasis dispelling; medicinal liquid and medicated powder share can adjust effectively that various functions participate in killing and eliminate hepatitis B virus in the body, purify the blood, improve the liver blood circulation, the protection hepatocyte, recover liver function, fundamentally cures hepatitis B.Instructions of taking: medicinal liquid day clothes 2 times, morning and afternoon each once, medicated powder sooner or later each once, each 4g.After clinical 37 routine hepatitis B patients were taken medicine, the front and back clearance time was 50--120 days, had 34 people to turn out cloudy and did not recur, and 3 people are invalid, negative conversion rate 91.8%.Therefore the present invention have can strengthen that hepatitis B patient immunologic function, damp eliminating blood stasis dispelling are invigorated blood circulation, the cure rate height, do not rebound after turning out cloudy, have no side effect, determined curative effect, abundant, the cheap advantage in medicine source, be a kind of medicine of novel therapeutic hepatitis B.
The specific embodiment
Be described in further detail the present invention below in conjunction with embodiment, but should understand the scope that scope of the present invention is not limited only to these embodiment.
Embodiment 1
1, the Radix Astragali, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Radix Codonopsis, Rhizoma Osmundae, Herba Damnacanthi, hemerocallitis,radix, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Serissae, italian-jobi jen root, cirsii japonici,radix and root of Indian kalimeris herb are cleaned respectively, remove impurity, be up to the standards;
2, the 300g Radix Astragali, 100g Herba Scutellariae Barbatae, 100g Herba Hedyotidis Diffusae, 50g Radix Codonopsis, 50g Rhizoma Osmundae, 100g Herba Damnacanthi, 300g hemerocallitis,radix, 50g Poria, the 100g Rhizoma Atractylodis Macrocephalae, 100g Radix Serissae and the 300g italian-jobi jen root that is up to the standards mixed put into medicinal cupping, decoct with water, obtain medicinal liquid after the filtration;
3, the 30g cirsii japonici,radix that is up to the standards and 30g root of Indian kalimeris herb are mixed the back and be ground into powder, obtain medicated powder with pulverizer;
4, medicine liquid irrigation is packed into bottle, with the medicated powder branch pouch of packing into, closing puts together again gets product.
Embodiment 2
1, the Radix Astragali, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Radix Codonopsis, Rhizoma Osmundae, Herba Damnacanthi, hemerocallitis,radix, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Serissae, italian-jobi jen root, cirsii japonici,radix and root of Indian kalimeris herb are cleaned respectively, remove impurity, be up to the standards;
2, the 600g Radix Astragali, 200g Herba Scutellariae Barbatae, 200g Herba Hedyotidis Diffusae, 100g Radix Codonopsis, 100g Rhizoma Osmundae, 300g Herba Damnacanthi, 600g hemerocallitis,radix, 100g Poria, the 300g Rhizoma Atractylodis Macrocephalae, 300g Radix Serissae and the 600g italian-jobi jen root that is up to the standards mixed put into medicinal cupping, decoct with water, obtain medicinal liquid after the filtration;
3, the 2000g cirsii japonici,radix that is up to the standards and 2000g root of Indian kalimeris herb are mixed the back and be ground into powder, obtain medicated powder with pulverizer;
4, medicine liquid irrigation is packed into bottle, with the medicated powder branch pouch of packing into, closing puts together again gets product.
Embodiment 3
1, the Radix Astragali, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Radix Codonopsis, Rhizoma Osmundae, Herba Damnacanthi, hemerocallitis,radix, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Serissae, italian-jobi jen root, cirsii japonici,radix and root of Indian kalimeris herb are cleaned respectively, remove impurity, be up to the standards;
2, the 500g Radix Astragali, 150g Herba Scutellariae Barbatae, 130g Herba Hedyotidis Diffusae, 70g Radix Codonopsis, 80g Rhizoma Osmundae, 200g Herba Damnacanthi, 400g hemerocallitis,radix, 60g Poria, the 180g Rhizoma Atractylodis Macrocephalae, 240g Radix Serissae and the 500g italian-jobi jen root that is up to the standards mixed put into medicinal cupping, decoct with water, obtain medicinal liquid after the filtration;
3, the 100g cirsii japonici,radix that is up to the standards and 150g root of Indian kalimeris herb are mixed the back and be ground into powder, obtain medicated powder with pulverizer;
4, medicine liquid irrigation is packed into bottle, with the medicated powder branch pouch of packing into, closing puts together again gets product.
Claims (2)
1, a kind of pharmaceutical composition for the treatment of hepatitis B is characterized in that: be made up of medicinal liquid and two kinds of medicines of medicated powder:
(1), medicinal liquid: form by following raw material in weight portion:
The Radix Astragali 50 Herba Scutellariae Barbataes 15 Herba Hedyotidis Diffusaes 13 Radix Codonopsis 7
Rhizoma Osmundae 8 Herba Damnacanthi 20 hemerocallitis,radixs 40 Poria 6
The Rhizoma Atractylodis Macrocephalae 18 Radix Serissae 24 Radix Semen Coiciss 50;
(2), medicated powder: form by following two kinds of raw materials in weight portion:
Cirsii japonici,radix 10 root of Indian kalimeris herb 15.
2, the method for the pharmaceutical composition of preparation treatment hepatitis B as claimed in claim 1 is characterized in that:
(1), the Radix Astragali, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Radix Codonopsis, Rhizoma Osmundae, Herba Damnacanthi, hemerocallitis,radix, Poria, the Rhizoma Atractylodis Macrocephalae, Radix Serissae, italian-jobi jen root, cirsii japonici,radix and root of Indian kalimeris herb are cleaned respectively, remove impurity, be up to the standards;
50 parts of Radixs Astragali that (2), will be up to the standards, 15 portions of Herba Scutellariae Barbataes, 13 parts of Herba Hedyotidis Diffusaes, 7 parts of Radix Codonopsis, 8 parts of Rhizoma Osmundae, 20 parts of Herba Damnacanthi, 40 parts of hemerocallitis,radixs, 6 parts of Poria, 18 parts of Rhizoma Atractylodis Macrocephalaes, 24 parts of Radix Serissae and 50 parts of italian-jobi jen roots mix puts into medicinal cupping, decoct with water, obtain medicinal liquid after the filtration;
(3), 10 parts of cirsii japonici,radixs that will be up to the standards and 15 parts of root of Indian kalimeris herb mix the back and are ground into powder with pulverizer, obtain medicated powder;
(4), with the medicine liquid irrigation bottle of packing into, with the medicated powder branch pouch of packing into, closing puts together again gets product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100677013A CN100350943C (en) | 2004-10-29 | 2004-10-29 | Medicinal composition for treating hepatitis B and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100677013A CN100350943C (en) | 2004-10-29 | 2004-10-29 | Medicinal composition for treating hepatitis B and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1634348A CN1634348A (en) | 2005-07-06 |
| CN100350943C true CN100350943C (en) | 2007-11-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB2004100677013A Expired - Fee Related CN100350943C (en) | 2004-10-29 | 2004-10-29 | Medicinal composition for treating hepatitis B and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102754674A (en) * | 2012-06-18 | 2012-10-31 | 李友军 | Liver-protecting and health-care loach freeze-dried flour and making method thereof |
| CN103860829A (en) * | 2014-04-01 | 2014-06-18 | 兰土生 | Traditional Chinese medicine oral solution for treating acute or chronic hepatitis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1230412A (en) * | 1998-03-31 | 1999-10-06 | 韩瑞星 | Turn-to-negative medicine powder to treat positive heaptitis B E-antigen |
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- 2004-10-29 CN CNB2004100677013A patent/CN100350943C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1230412A (en) * | 1998-03-31 | 1999-10-06 | 韩瑞星 | Turn-to-negative medicine powder to treat positive heaptitis B E-antigen |
Non-Patent Citations (1)
| Title |
|---|
| 肝泰92治疗慢性乙型肝炎的临床观察 郭翔，谭行华，张穗坚.新中医，第24卷第12期 1992 * |
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| CN1634348A (en) | 2005-07-06 |
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Granted publication date: 20071128 Termination date: 20091130 |