CN100350934C - Baidianxiao treaditional Chinese medicine for treating vitiligo and preparation method thereof - Google Patents
Baidianxiao treaditional Chinese medicine for treating vitiligo and preparation method thereof Download PDFInfo
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Abstract
The present invention discloses a traditional Chinese medicine composition, namely Baidianxiao, for treating vitiligo and a preparation method thereof. The traditional Chinese medicine comprises the following raw material components: serissa, siegesbeckia, tribulus fruit, psoralea fruit, snake slough, table salt, purslane herb, ginger juice, eggplant pedicle, scorpion, smoked plum, pink plumepoppy herb, white snake, honeycomb, dahurian angelica, angelica, boracic acid, safflower, yerbadetajo herb, barbary wolfberry fruit, fleeceflower root, realgar, lithargite and sulfur. The raw medicinal materials are mixed and extracted by adding ethanol; the obtained extraction solution is filtered; the obtained filter liquor is cooled; the realgar, the lithargite and the sulfur are added into the filter liquor for soaking for 5 to 10 days; then, the liquor is filtered; the obtained filter liquor is prepared into various preparation forms by a preparation method of a conventional externally applied medicine for skin, and then the traditional Chinese medicine composition is obtained. The traditional Chinese medicine composition has an obvious curative effect on intractable vitiligo, and has the advantage of no toxic or side effect.
Description
Technical field
The present invention relates to the dermopathic medicine of a kind of treatment, relate in particular to leukodermic medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition of a kind of treatment and preparation method thereof.
Background technology
Vitiligo is still one of the world's four big pertinacious diseases so far, and it is obstinate that the state of an illness that in recent years should disease also tends to, and is one of disease of World Health Organization (WHO) and skin research field primary study and control.This disease cause of disease is unclear fully as yet so far.It is generally acknowledged relevant with multiple factors such as heredity, infection, immunity, metabolism, endocrine, spirit.How vitiligo can not form melanin by skin and cause that symptom is to present blocks of white macula on the skin, and is superficial, also claims leukoderma.
At present, therapy for vitiligo is mainly based on medicine, though the method for treatment is many, can only reach recent clinical effectiveness mostly, and recurrence is difficult to suppress.Western medicine adopts 17-hydroxy-11-dehydrocorticosterone or cellular immunization inhibitor more, though this class medicine has short term effect preferably, but the disadvantage that they exist is epidermis and the corium attenuation that life-time service can make skin, and can cause serious toxicity such as telangiectasis and addiction, complication is many, subject range is little, and price is also relatively more expensive, is not the leukodermic direction of treatment; And the shortcoming that treatment by Chinese herbs exists uncertain therapeutic efficacy to cut.
Summary of the invention
The purpose of this invention is to provide the dermopathic medicine of a kind of treatment, leukodermic medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition of a kind of treatment and preparation method thereof especially is provided, it is serious to have overcome present western medicine toxicity, the shortcoming that treatment by Chinese herbs exists uncertain therapeutic efficacy to cut.
The objective of the invention is to be achieved through the following technical solutions:
A kind of medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition comprises following component: Radix Serissae, Herba Siegesbeckiae, Fructus Atriplicis Sibiricae, Fructus Psoraleae, Periostracum Serpentis, Sal, Herba Portulacae, Sucus Zingberis, the Fructus Solani melongenae base of a fruit, Scorpio (annotate: the formal name used at school of " Scorpio " is " Scorpio "), Fructus Mume, Herba Macleayae Cordatae, white Serpentis, Nidus Vespae, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, boric acid, Flos Carthami, Herba Ecliptae, Fructus Lycii, Radix Polygoni Multiflori, Realgar, Lithargyrum, sulfur;
Described component can be following parts by weight of component: Radix Serissae 15-20 Herba Siegesbeckiae 10-15, Fructus Atriplicis Sibiricae 15-25, Fructus Psoraleae 20-30, Periostracum Serpentis 10-15, Sal 30-50, Herba Portulacae 15-30, Sucus Zingberis 25-30, Fructus Solani melongenae base of a fruit 30-40, Scorpio (formal name used at school is " Scorpio ") 10-15, Fructus Mume 30-35, Herba Macleayae Cordatae 20-25, white Serpentis 20-25, Nidus Vespae 10-15, Radix Angelicae Dahuricae 20-30, Radix Angelicae Sinensis 15-20, boric acid 30-35, Flos Carthami 20-25, Herba Ecliptae 15-20, Fructus Lycii 20-25, Radix Polygoni Multiflori 15-20, Realgar 50-60, Lithargyrum 40-45, sulfur 30-45;
Described component is preferably following parts by weight of component: Radix Serissae 18, Herba Siegesbeckiaes 12, Fructus Atriplicis Sibiricae 20, Fructus Psoraleae 25, Periostracum Serpentis 12, Sal 40, Herba Portulacae 22, Sucus Zingberis 28, the Fructus Solani melongenae base of a fruit 35, Scorpio 12, Fructus Mume 32, Herba Macleayae Cordatae 22, white Serpentis 22, Nidus Vespae 12, the Radix Angelicae Dahuricae 25, Radix Angelicae Sinensis 18, boric acid 32, Flos Carthami 22, Herba Ecliptae 18, Fructus Lycii 22, Radix Polygoni Multiflori 18, Realgar 55, Lithargyrum 42, sulfur 38;
Described medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition can be made into said external preparation for skin dosage form on any pharmaceutics, especially is water preparation, varnish, unguentum, spray.
The preparation method of a kind of medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition of the present invention may further comprise the steps:
Get the above-mentioned raw materials medicine, mix, add ethanol or water extraction, extracting liquid filtering adds Realgar, Lithargyrum, sulfur and soaked 5-10 days, filters, get filtrate routinely external preparation for skin pharmaceutical preparation method make various dosage forms promptly.
Described method also comprises: after getting the above-mentioned raw materials medicine and concocting respectively, mix, or be ground into corase meal altogether, put into container such as marmite, vial, and to add concentration be the ethanol of 45-80% that preferably concentration is that 80% soak with ethanol raw material gets final product; Slow fire boils 2 times-3 times, filters, and gets filtrate; Filtrate is put cold, and adding Realgar, Lithargyrum, sulfur soaked 5-10 days, especially were 7 days; Soak filters, and gets filtrate, makes various dosage forms in external preparation for skin pharmaceutical preparation method routinely, and fill promptly gets described medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition.
Using method: impose on the vitiligo affected part, every day 3-4 time, two months is a course of treatment, and can cure general 2-3 course of treatment; Preferably every day with ginger slice wiping vitiligo affected part to little red after, the reuse Rhizoma Zingiberis Recens is stained with medicine juice and is put affected part on the skin, every day 3-4 time, two months is a course of treatment, can cure general 2-3 course of treatment, discrete patient 4-5 the healing course of treatment, suitable various vitiligo.
Ingredient effect of the present invention:
Radix Serissae, bitter, hot, cool, cold in nature, nontoxic, have and dispel the wind, heat clearing away, the effect of detoxifcation.
Herba Siegesbeckiae, is gone into the Liver and kidney warp, settling five organs, hair growth promoting, hair color, nourishing YIN and benefiting blood, the tonify deficiency of clothes, but curing vitiligo at bitter, cold, little suffering.
Fructus Atriplicis Sibiricae, bitter, hot, warm in nature, go into liver lung stomach warp, the wind therapeutic method to keep the adverse QI flowing downwards promoting the circulation of blood of loosing, the speckle that goes out, but curing vitiligo.
Fructus Psoraleae, bitter, hot, warm in nature, return the kidney spleen channel, the external curing vitiligo contains Fructus Psoraleae and different benefit fat element, can promote the newborn of dermal melanin and cause photosensitization, can expand local vascular, improves histotrophic nutrition.
Periostracum Serpentis contains osseocolla essence etc., and the Periostracum Serpentis extract that boils has antiinflammatory action, can suppress leukocytic hypertrophy and the permeability of blood vessel is provided, but curing vitiligo.
Sal relieves inflammation or internal heat, removing heat from blood, detoxifcation, controls pathogen, mends skin raw meat, blood circulation promoting and blood stasis dispelling, removing heat from blood and moisturizes.Dispel the wind, kill fire, polyphagia can make colour of skin brilliant black, and vitiligo mostly is disharmony between QI and blood, or the Liver and kidney asthenia of essence and blood, or multiple paathogenic factor such as stagnation of blood stasis wind-engaging causes imbalance of YIN and YANG, causes that local melanin disappears, Sal can make blood vessels condense and variable color, can urge Intradermal melanin and generate, so but curing vitiligo.
Herba Portulacae, hot, cold, little acid, heat-clearing and toxic substances removing, QI invigorating, removing food stagnancy stagnates, and kills fire, and cooperate curing vitiligo to imitate with boric acid excellent.
Realgar, the detoxifcation parasite killing goes dampness, dispels the wind.
Sucus Zingberis promotes skin venation microcirculation, promotes the absorption of medicine to affected part.
The Fructus Solani melongenae base of a fruit contains a large amount of ferrous components, promotes the affected part metabolism, but curing vitiligo.
Scorpio, suffering, poisonous, go into Liver Channel, meridian passage dredging detoxication is controlled tinea corporis, fish scale.
Fructus Mume, sour in the mouth, temperature, flat, nontoxic, control dead flesh, melanotic nevus, to go into dead flesh, dislike meat, melanotic nevus then removes, incarnation is controlled psoriasis, children's's tinea alba disease such as do not heal for many years, but the external curing vitiligo.
Sulfur, topical application has the cutin of clearing up to skin, the effect of softening skin, pain relieving, infection, the protection wound surface promotes healing, to scrotum, labia, pruritus due to damp pathogen, scabies, malignant boil, bald, and cuts dried exudative dermatitis etc. and curing vitiligo.
Herba Macleayae Cordatae, bitter, hot, warm in nature, very toxic, detumescence, detoxifcation, parasite killing can be made last the accent and be coated with curing vitiligo.
White Serpentis, Serpentis property is walked to scurry, and also benefaction nowhere less than, so can draw the fresh breeze medicine, reach also from internal organs to sick institute, what solid wind was given birth to prolongs, and makes its power obtaining recovery from illness invariably, and Serpentis is the special medicine of vitiligo specially except that the wind of the bottom of heart in vain.
Nidus Vespae, sweet, put down, return the stomach warp, have merit poisoning worm, wind-expelling pain-stopping, and can treat carbuncle, scrofula, the effect of tinea skin ulcer.
The Radix Angelicae Dahuricae can go the dried defect tinea of dough cover, and the wind of the skin migration of dispelling is treated wind, controls skin Pruritus such as welt, decortication, wet dry, sepage, can control scabies, longue skin etc.
Radix Angelicae Sinensis, Gan Xin, temperature, nontoxic, be the promoting the circulation of blood medicine of enriching blood.
Boric acid can be transferred pH value in this medicine, make it stored for a long time.
Flos Carthami is invigorated blood circulation, blood stasis removing, and color has been made us in pain relieving.
Herba Ecliptae, removing heat from blood, hemostasis, black beard and hair, kidney tonifying the moon can be taken a tonic or nourishing food to build up one's health melanin, thus but curing vitiligo.
Fructus Lycii is gone into the Autoscreen II lung meridian, the nourishing kidney lung moistening, and tonifying liver makes eye bright, and makes longue meat, beneficial color.
Radix Polygoni Multiflori is made ripe the kidney invigorating, benefiting essence-blood, and black beard and hair, controlling nocturnal emission with astringent drugs gas, beneficial vim and vigour, black hair on the temple, improving healthy complexion is controlled the skin ulcer scabies, stubborn dermatitis, red vitiligo.
The Lithargyrum as medicine for external use, can reduce inflammation, and has convergence anticorrosion, detumescence poison, and scar is done on the face that goes out, to remove tinea versicolor external curing vitiligo effective.
Stone sulfur is ground into powder, and is hot flat, poisonous, scorching, and scabies is controlled in the parasite killing detoxifcation, bald, crusted scabies, and itching over the body, the dead flesh of skin that looses, absentminded evil thought is controlled tinea.
The present invention has the following advantages:
1, medicine-feeding is closed and is gathered, and can dispel the wind, detoxifies, invigorates blood circulation, removing heat from blood, has nourishing the liver and kidney, benefiting QI and nourishing blood, and removing heat from blood, the granulation promoting skin moistening is taken a tonic or nourishing food to build up one's health melanin, has made us color, the many types of vitiligo of treatment of can dispeling the wind.
2, short treating period, instant effect has no side effect.
3, need not other medicines cooperate, direct wiping white macula position, if every day with Rhizoma Zingiberis Recens erasing vitiligo affected part to little red after, the reuse Rhizoma Zingiberis Recens is stained with medicine juice and is put affected part on the skin, more remarkable treatment effect.
The insane syndrome caused by wind pathogen disease of medicine dialogue of the present invention clinical case efficacy analysis
From year June in October, 2002 to 2003, treat vitiligo 250 examples altogether in Linquan County, Anhui hospital dermatology department out-patient department, wherein male 145 examples, women 105 examples.
Using method: medicine is embodiment 1 varnish, and cleaning skin is embrocated this medicine on the surface, affected part, and every day 3 times, 7 days is a course of treatment.
Curative effect judging standard: 1. clinical cure: skin color recovers normal, and no vestige is as excellent as before, glossy as jade; 2. produce effects: white macula obviously disappears, and transfers brown white to by pure white, gradually to normal skin; 3. take a turn for the better: white macula gradually transfers erythema to, and foxiness occurs; 4. invalid: medication does not have significant change after 2 months; 5. recurrence: follow the trail of after 3 years and pay a return visit.Observation shows that only 3 patients have slight anasarca, and 1-2 disappears after week or after the drug withdrawal, does not influence treatment.
Table 5 Drug therapy vitiligo of the present invention disease efficacy analysis
| Name of disease (people) | Example number (people) | Cure (people) | Produce effects (people) | Take a turn for the better (people) | Invalid (%) | Effective percentage (people) | Recurrence (%) | Relapse rate |
| Vitiligo | 250 | 175 | 64 | 11 | 0 | 100 | 21 | 12 |
The specific embodiment
Embodiment 1
Water preparation
Take by weighing each component (kg) by following proportioning: Radix Serissae 18, Herba Siegesbeckiaes 12, Fructus Atriplicis Sibiricae 20, Fructus Psoraleae 25, Periostracum Serpentis 12, Sal 40, Herba Portulacae 22, Sucus Zingberis 28, the Fructus Solani melongenae base of a fruit 35, Scorpio 12, Fructus Mume 32, Herba Macleayae Cordatae 22, white Serpentis 22, Nidus Vespae 12, the Radix Angelicae Dahuricae 25, Radix Angelicae Sinensis 18, boric acid 32, Flos Carthami 22, Herba Ecliptae 18, Fructus Lycii 22, Radix Polygoni Multiflori 18, Realgar 55, Lithargyrum 42, sulfur 38.
Preparation method may further comprise the steps: get above-mentioned raw materials, be mixed in proportion, be ground into corase meal, cross 10 mesh sieves, put into marmite, and to add concentration be that 50% soak with ethanol raw material gets final product; Slow fire boils twice, filters, and gets filtrate; Filtrate is put cold, and adding Realgar, Lithargyrum, sulfur soaked 7 days; Soak filters, and gets filtrate, and it is 100L that the adjustment water content makes solution, fill, and 100 ℃ of steam sterilizations promptly got water preparation in 20 minutes.
Embodiment 2
Varnish
Take by weighing each component (kg) by following proportioning: Radix Serissae 20, Herba Siegesbeckiaes 15, Fructus Atriplicis Sibiricae 25, Fructus Psoraleae 30, Periostracum Serpentis 15, Sal 50, Herba Portulacae 30, Sucus Zingberis 30, the Fructus Solani melongenae base of a fruit 40, Scorpio 15, Fructus Mume 35, Herba Macleayae Cordatae 25, white Serpentis 25, Nidus Vespae 15, the Radix Angelicae Dahuricae 30, Radix Angelicae Sinensis 20, boric acid 35, Flos Carthami 25, Herba Ecliptae 20, Fructus Lycii 25, Radix Polygoni Multiflori 20, Realgar 60, Lithargyrum 45, sulfur 45g.
Preparation method may further comprise the steps: get above-mentioned raw materials, be mixed in proportion, be ground into corase meal, cross 10 mesh sieves, put into marmite, and to add concentration be that 80% soak with ethanol raw material gets final product; Slow fire boils 3 times, filters, and gets filtrate; Filtrate is put cold, and adding Realgar, Lithargyrum, sulfur soaked 10 days; Soak filters, and gets filtrate, concentrates, and adjusting water content is 20%, fill, and 1000,10g/ props up, and cobalt 60 is sterilized 15 minutes promptly.
Embodiment 3
Unguentum
Take by weighing each component (kg) by following proportioning: Radix Serissae 15, Herba Siegesbeckiaes 10, Fructus Atriplicis Sibiricae 15, Fructus Psoraleae 20, Periostracum Serpentis 10, Sal 30, Herba Portulacae 15, Sucus Zingberis 25, Fructus Solani melongenae base of a fruit 30-40, Scorpio 10, Fructus Mume 30, Herba Macleayae Cordatae 20, white Serpentis 20, Nidus Vespae 10, the Radix Angelicae Dahuricae 20, Radix Angelicae Sinensis 15, boric acid 30, Flos Carthami 20, Herba Ecliptae 15, Fructus Lycii 20, Radix Polygoni Multiflori 15, Realgar 50, Lithargyrum 40, sulfur 30.
Preparation method may further comprise the steps: get above-mentioned raw materials, be mixed in proportion, be ground into coarse powder, put into marmite, and to add concentration be that 45% soak with ethanol raw material gets final product; Slow fire boils 3 times, filters, and gets filtrate; Filtrate is put cold, and adding Realgar, Lithargyrum, sulfur soaked 5 days; Soak filters, and gets filtrate, concentrates to be thick shape, add excipient octadecanol 4 grams, stearic acid 10 grams, glyceryl monostearate 5 grams, vaseline 6 grams, glycerol 10 grams, triethanolamine 0.8 gram and surplus distilled water are mixed with unguentum, fill, 10g/ props up, and 100 ℃ of steam sterilizations 15 minutes promptly.
Embodiment 4
Spray
Take by weighing each component (kg) by following proportioning: Radix Serissae 16, Herba Siegesbeckiaes 11, Fructus Atriplicis Sibiricae 22, Fructus Psoraleae 26, Periostracum Serpentis 13, Sal 437, Herba Portulacae 21, Sucus Zingberis 26, the Fructus Solani melongenae base of a fruit 32, Scorpio 13, Fructus Mume 30, Herba Macleayae Cordatae 21, white Serpentis 23, Nidus Vespae 13, the Radix Angelicae Dahuricae 24, Radix Angelicae Sinensis 17, boric acid 30, Flos Carthami 23, Herba Ecliptae 19, Fructus Lycii 21, Radix Polygoni Multiflori 19, Realgar 54, Lithargyrum 41, sulfur 39.
Preparation method may further comprise the steps: get above-mentioned raw materials, be mixed in proportion, put into container, and to add concentration be that 50% soak with ethanol raw material gets final product; Slow fire boils twice, filters, and gets filtrate; Filtrate is put cold, and adding Realgar, Lithargyrum, sulfur soaked 10 days; Soak filters, and gets filtrate, and adjusting water content, to make solution be 1000L, the fill spray bottle, and the 50ml/ bottle, 100 ℃ of steam sterilizations 30 minutes, promptly.
Claims (7)
1, a kind of medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition is made by each crude drug of following weight portion: Radix Serissae 15-20 part Herba Siegesbeckiae 10-15 part, Fructus Atriplicis Sibiricae 15-25 part, Fructus Psoraleae 20-30 part, Periostracum Serpentis 10-15 part, Sal 30-50 part, Herba Portulacae 15-30 part, Sucus Zingberis 25-30 part, Fructus Solani melongenae base of a fruit 30-40 part, Scorpio 10-15 part, Fructus Mume 30-35 part, Herba Macleayae Cordatae 20-25 part, white Serpentis 20-25 part, Nidus Vespae 10-15 part, Radix Angelicae Dahuricae 20-30 part, Radix Angelicae Sinensis 15-20 part, boric acid 30-35 part, Flos Carthami 20-25 part, Herba Ecliptae 15-20 part, Fructus Lycii 20-25 part, Radix Polygoni Multiflori 15-20 part, Realgar 50-60 part, Lithargyrum 40-45 part, sulfur 30-45 part.
2, medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition according to claim 1, described component is following parts by weight of component: Radix Serissae 18 12 parts of Fen, Herba Siegesbeckiaes, 20 parts of Fructus Atriplicis Sibiricaees, 25 parts of Fructus Psoraleaes, 12 parts of Periostracum Serpentiss, 40 parts of Sal, 22 parts of Herba Portulacaes, 28 parts of Sucus Zingberis, 35 parts of the Fructus Solani melongenae bases of a fruit, 12 parts of Scorpios, 32 parts of Fructus Mumes, 22 parts of Herba Macleayae Cordatae, 22 parts of white Serpentiss, 12 parts in Nidus Vespae, 25 parts of the Radixs Angelicae Dahuricae, 18 parts of Radix Angelicae Sinensis, 32 parts of boric acid, 22 parts on Flos Carthami, 18 parts of Herba Ecliptaes, 22 parts of Fructus Lycii, 18 parts of Radix Polygoni Multiflori, 55 parts of Realgars, 42 parts of Lithargyrums, 38 parts of sulfurs.
3, medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition according to claim 1, described medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition are said external preparation for skin dosage form on any pharmaceutics.
4, medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition according to claim 1, described medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition is water preparation, varnish, unguentum, spray.
5, a kind of preparation method of medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition may further comprise the steps:
The weighting profit requires the 1-2 crude drug, mixes, and adds ethanol or water extraction, extracting liquid filtering, adding Realgar, Lithargyrum, sulfur soaked 5-10 days, filtered, get filtrate routinely external preparation for skin pharmaceutical preparation method make various dosage forms, promptly get described medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition.
6, the preparation method of medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition according to claim 5, described method also comprises: the weighting profit requires the 1-2 crude drug to be ground into coarse powder altogether, puts into container, and adding concentration is that the soak with ethanol raw material of 45-80% gets final product; Slow fire boils 2 times-3 times, filters, and gets filtrate; Filtrate is put cold, and adding Realgar, Lithargyrum, sulfur soaked 5-10 days; Soak filters, and gets filtrate, and external preparation for skin pharmaceutical preparation method is made various dosage forms routinely, promptly gets described medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition.
7, the preparation method of medicine ' Baidianxiao ' for treating leukoderma Chinese medicine composition according to claim 6, described concentration of alcohol are 80%; It is 7 days that described adding Realgar, Lithargyrum, sulfur soak.
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100450524C (en) * | 2005-12-21 | 2009-01-14 | 李德峰 | Chinese medicine composition for treating facial skin disease and its preparing method |
| CN101204410B (en) * | 2007-12-19 | 2011-09-21 | 干慕美 | External medicine for vitligo |
| CN103505574A (en) * | 2013-06-28 | 2014-01-15 | 保定华仁白癜风医院 | Traditional Chinese medicine ointment used for treating leucoderma, and preparation method thereof |
| CN104491170A (en) * | 2014-11-23 | 2015-04-08 | 溧阳市天目湖大紫王葡萄专业合作社 | Traditional Chinese medicinal composition for treating pathogenic wind type leucoderma |
| CN106215122A (en) * | 2016-08-31 | 2016-12-14 | 亳州市庆聚药业销售有限公司 | Traditional Chinese medicine formula for treating leucoderma |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1202375A (en) * | 1998-06-29 | 1998-12-23 | 叶庆莲 | Chinese drug for curing vitiligo |
| CN1337266A (en) * | 2001-09-24 | 2002-02-27 | 杨国帅 | Leukoderma liniment |
| CN1127348C (en) * | 2001-07-17 | 2003-11-12 | 张仲武 | Leukoderma treating medicine |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1202375A (en) * | 1998-06-29 | 1998-12-23 | 叶庆莲 | Chinese drug for curing vitiligo |
| CN1127348C (en) * | 2001-07-17 | 2003-11-12 | 张仲武 | Leukoderma treating medicine |
| CN1337266A (en) * | 2001-09-24 | 2002-02-27 | 杨国帅 | Leukoderma liniment |
Non-Patent Citations (1)
| Title |
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| 中医药治疗白癜风近况 贾静.中医药信息，第2期 2003 * |
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