CN100348525C - Biological activity glass ceramics capable of cutting and its preparation method - Google Patents
Biological activity glass ceramics capable of cutting and its preparation method Download PDFInfo
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- CN100348525C CN100348525C CNB2004100792789A CN200410079278A CN100348525C CN 100348525 C CN100348525 C CN 100348525C CN B2004100792789 A CNB2004100792789 A CN B2004100792789A CN 200410079278 A CN200410079278 A CN 200410079278A CN 100348525 C CN100348525 C CN 100348525C
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- 239000002241 glass-ceramic Substances 0.000 title claims abstract description 46
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 230000004071 biological effect Effects 0.000 title description 14
- 239000011521 glass Substances 0.000 claims abstract description 36
- 239000011159 matrix material Substances 0.000 claims abstract description 20
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229910002804 graphite Inorganic materials 0.000 claims abstract description 13
- 239000010439 graphite Substances 0.000 claims abstract description 13
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000000203 mixture Substances 0.000 claims abstract description 8
- 239000000843 powder Substances 0.000 claims abstract description 8
- 238000010791 quenching Methods 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 230000000975 bioactive effect Effects 0.000 claims abstract description 6
- 229910052587 fluorapatite Inorganic materials 0.000 claims abstract description 5
- 239000013078 crystal Substances 0.000 claims abstract description 3
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 239000006060 molten glass Substances 0.000 claims abstract 2
- GALOTNBSUVEISR-UHFFFAOYSA-N molybdenum;silicon Chemical compound [Mo]#[Si] GALOTNBSUVEISR-UHFFFAOYSA-N 0.000 claims abstract 2
- 229910004261 CaF 2 Inorganic materials 0.000 claims description 10
- 229910004298 SiO 2 Inorganic materials 0.000 claims description 9
- 238000004455 differential thermal analysis Methods 0.000 claims description 2
- 229910018072 Al 2 O 3 Inorganic materials 0.000 claims 3
- 239000004615 ingredient Substances 0.000 claims 2
- 238000010438 heat treatment Methods 0.000 claims 1
- 238000001556 precipitation Methods 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 abstract description 11
- 239000000463 material Substances 0.000 abstract description 10
- 239000000126 substance Substances 0.000 abstract description 3
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 abstract description 2
- 210000003298 dental enamel Anatomy 0.000 abstract description 2
- 230000008439 repair process Effects 0.000 abstract description 2
- 230000007547 defect Effects 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000009413 insulation Methods 0.000 description 17
- 238000000034 method Methods 0.000 description 15
- 238000012545 processing Methods 0.000 description 12
- 238000005452 bending Methods 0.000 description 11
- 238000001816 cooling Methods 0.000 description 10
- 238000005553 drilling Methods 0.000 description 10
- 229910052782 aluminium Inorganic materials 0.000 description 7
- 229910006295 Si—Mo Inorganic materials 0.000 description 6
- 238000000498 ball milling Methods 0.000 description 6
- 230000000171 quenching effect Effects 0.000 description 6
- 239000012890 simulated body fluid Substances 0.000 description 6
- 229910000997 High-speed steel Inorganic materials 0.000 description 5
- 208000037656 Respiratory Sounds Diseases 0.000 description 5
- 241001074085 Scophthalmus aquosus Species 0.000 description 5
- 238000002441 X-ray diffraction Methods 0.000 description 5
- 238000002149 energy-dispersive X-ray emission spectroscopy Methods 0.000 description 5
- 238000002844 melting Methods 0.000 description 5
- 230000008018 melting Effects 0.000 description 5
- 229910052751 metal Inorganic materials 0.000 description 5
- 239000002184 metal Substances 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 238000013001 point bending Methods 0.000 description 5
- 238000005498 polishing Methods 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 238000005507 spraying Methods 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 238000012546 transfer Methods 0.000 description 5
- 230000000007 visual effect Effects 0.000 description 5
- 239000012620 biological material Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 229940077441 fluorapatite Drugs 0.000 description 3
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 3
- 239000000919 ceramic Substances 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- 229910000771 Vitallium Inorganic materials 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000000602 vitallium Substances 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C4/00—Compositions for glass with special properties
- C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C10/00—Devitrified glass ceramics, i.e. glass ceramics having a crystalline phase dispersed in a glassy phase and constituting at least 50% by weight of the total composition
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Geochemistry & Mineralogy (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Ceramic Engineering (AREA)
- Crystallography & Structural Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Glass Compositions (AREA)
Abstract
本发明涉及硅酸盐材料领域，该材料应用于骨、齿缺损的修复与替代。其特征在于：将按重量百分比配制好的原料装入氧化铝球磨罐中混合均匀；接着倒入氧化铝坩埚中，在硅钼棒炉中高温熔炼；然后将熔融的玻璃浇于水中淬冷、烘干后磨碎；将这些玻璃粉再进行重熔后浇铸到石墨模具中，在500～700℃保温1h，随炉冷却至室温，得到成分均匀的玻璃母体；再升温至800～1100℃保温4～24h，使母体玻璃受控析出含有氟金云母和氟磷灰石两种主晶相的玻璃陶瓷。本发明制备的医用可切削生物活性玻璃陶瓷，其抗弯强度、弹性模量符合人体骨、齿的力学性能要求，能与人体骨组织直接产生强的化学键合；其色泽与人体牙釉质十分相近，适合用于齿科替代材料；且其制备工艺简单，技术成熟，易于操作。The invention relates to the field of silicate materials, which are applied to the repair and replacement of bone and tooth defects. It is characterized in that: the raw materials prepared according to the weight percentage are put into an alumina ball mill jar and mixed evenly; then poured into an alumina crucible and smelted at a high temperature in a silicon-molybdenum rod furnace; then the molten glass is poured into water to quench, Grind after drying; remelt the glass powder and cast it into a graphite mold, keep it at 500-700°C for 1 hour, and cool it to room temperature with the furnace to obtain a glass matrix with uniform composition; then heat it up to 800-1100°C and keep it warm 4 to 24 hours, the matrix glass is controlled to precipitate glass ceramics containing two main crystal phases of fluorphlogopite and fluoroapatite. The medical machinable bioactive glass-ceramic prepared by the present invention has the flexural strength and elastic modulus in line with the mechanical performance requirements of human bones and teeth, and can directly produce strong chemical bonds with human bone tissue; its color is very similar to human enamel , suitable for dental substitute materials; and its preparation process is simple, mature and easy to operate.
Description
Technical field:
The present invention relates to especially a kind of biological activity glass ceramics capable of cutting in silicate material field and preparation method thereof, this material is applied to the damaged reparation of bone, tooth and substitutes.
Background technology:
Traditional biomaterial for medical purpose mostly is titanium alloy, stainless steel, vitallium, macromolecular material PMMA etc., these materials are because biocompatibility is poor, as in bone, the tooth equivalent material implant into body time, easily form the fibering packing, can not produce chemical bonding closely with osseous tissue, be easy to loose or dislocation.In recent years, biological ceramics is as a kind of novel biomaterial for medical purpose, and is subjected to extensive concern.But the ceramic-like materials difficulty of processing is big, and the profile of human body bone, tooth different and widely different because of individual and concrete position, thereby the processing difficulties of biological ceramics has limited its application in bone, tooth repair materials.
Summary of the invention:
The purpose of this invention is to provide a kind of have good machinability and bioactive medical glass stupalith and preparation method.
Biological activity glass ceramics capable of cutting of the present invention is (wt%) SiO by weight percentage
252-28%, Al
2O
311-5%, MgO 14-7%, NaF 15-8%, CaHPO
46-32%, CaCO
32-14%, CaF
2The 1-5% preparation is respectively 50～90% and 10～50% in the hope of fluorophlogopite and fluorapatite two-phase in the final glass-ceramic.
Biological activity glass ceramics capable of cutting preparation method of the present invention is: at first with raw materials by weight (wt%) SiO
252-28%, Al
2O
311-5%, MgO 14-7%, NaF 15-8%, CaHPO
46-32%, CaCO
32-14%, CaF
21-5% prepares, and mixes in the aluminum oxide ball milling jar of packing into; Then pour in the alumina crucible high melt in the Si-Mo rod stove into; Then fused glass is watered in water and grind after quenching, the oven dry.These glass powder are carried out being cast in the graphite jig after the remelting again,,, cool to room temperature with the furnace, obtain the uniform glass matrix of composition at 500～700 ℃ of insulation 1h before this with mold heated to 400～600 ℃; Determine suitable heat treating regime through the DTA differential thermal analysis, be warming up to 800～1100 ℃ of insulation 4～24h again, make the controlled glass-ceramic that contains fluorophlogopite and two kinds of principal crystalline phases of fluorapatite of separating out of mother glass.Owing to form by phosphatic rock more than 70% in the bone of human body, the tooth, therefore, fluorapatite has given glass-ceramic good biological activity and biocompatibility, the fluorophlogopite of laminate structure is owing to have very strong divisibility along (001) crystal face simultaneously, have good machinable performance, thereby make this glass-ceramic have machinability and biological activity concurrently.
The present invention is used for each ionic concn (10 of simulated body fluid of biological activity glass ceramics capable of cutting
-3Mol/L) be: Na
+142.0, K
+5.0, Mg
2+1.5, Ca
2+2.5, Cl
-147.8, HCO
3 -4.2, HPO
4 2-1.0, SO
4 2-0.5.
Advantage of the present invention and positively effect demonstrate fully in following several respects:
The medical machinable biological active glass ceramic of the present invention's preparation, its bending strength, Young's modulus meet the performance requriements of human body bone, tooth, have good biological activity and biocompatibility simultaneously, can directly produce strong chemical bonding with body bone tissue, and tissue is not had any toxic action, it is a kind of ideal novel biomaterial, its color and luster and human body enamel are very close, especially be suitable for tooth section equivalent material, and its preparation technology are simple, technology maturation, easy handling.
Embodiment:
Embodiment 1: press SiO
245.9%, Al
2O
39.2%, MgO 11.8%, and NaF 13.1%, CaHPO
412.6%, CaCO
35.4%, CaF
22.0% batching mixing; Pour in the alumina crucible, 1500 ℃ of following meltings are 2 hours in the Si-Mo rod stove, and heat-up rate is 5 ℃/min, and fused glass is watered quenching in water, below ball milling to the 74 μ m of oven dry back; These glass powders are carried out being cast in the graphite jig after the remelting under identical condition again,, immediately graphite jig is moved in the process furnace, obtain glass matrix at 650 ℃ of insulations furnace cooling after 1 hour before this with mold heated to 500～600 ℃; Then glass matrix is warmed up to 925 ℃ of insulations 6 hours from room temperature, heat-up rate is 10 ℃/min, takes out after cooling to room temperature with the furnace.After the glass-ceramic sample processing polishing that makes, be of a size of 3 * 4 * 35mm, adopting three-point bending method test bending strength on CSS-44100 type electronic universal tester is 134MPa, Young's modulus is 12GPa.
Perhaps be incubated 20 hours at 925 ℃ after obtaining glass matrix, recording its bending strength under same condition is 153MPa, and Young's modulus is 15GPa.
Sample is soaked in constant temperature in 37 ℃, pH value transfer to 7.4 simulated body fluid, take out after 3 days, the surface is carried out microscopic appearance behind the metal spraying and is observed, the resultant of sample surfaces is carried out X-ray analysis and in conjunction with EDAX micro-area composition analytical results at D/max-2500 type superpower X-ray diffractometer on JSM-5600LV type scanning electron microscope, discovery has a large amount of fluorapatites to generate at sample surfaces, shows that this kind glass-ceramic has high biological activity.
The method that employing is holed on drilling machine is weighed the cutting ability of glass-ceramic, the boring processing conditions is: constant axial power is 392N, and High Speed Steel Bit, bit diameter are Φ 3mm, rotating speed is 400r/min, drilling time is 15s, and a drill bit is changed in hole of every brill, and the result shows, 925 ℃ the insulation 6 hours or 20 hours after, the mean depth of glass-ceramic boring is respectively 2.6mm and 2.8mm, and the no visual crackle of hole periphery, does not have and be out of shape, and has shown the good machinability of this glass-ceramic.
Embodiment 2: press SiO
234.4%, Al
2O
36.9%, MgO 8.9%, and NaF 9.8%, CaHPO
425.3%, CaCO
310.7%, CaF
24.0% batching mixing; Pour in the alumina crucible, 1500 ℃ of following meltings are 2 hours in the Si-Mo rod stove, and heat-up rate is 5 ℃/min, and fused glass is watered quenching in water, below ball milling to the 74 μ m of oven dry back; These glass powders are carried out being cast in the graphite jig after the remelting under identical condition again,, immediately graphite jig is moved in the process furnace, obtain glass matrix at 650 ℃ of insulations furnace cooling after 1 hour before this with mold heated to 500～600 ℃; Then glass matrix is warmed up to 925 ℃ of insulations 6 hours from room temperature, heat-up rate is 10 ℃/min, takes out after cooling to room temperature with the furnace.After the glass-ceramic sample processing polishing that makes, be of a size of 3 * 4 * 35mm, adopting three-point bending method test bending strength on CSS-44100 type electronic universal tester is 168MPa, Young's modulus is 21GPa.
Perhaps be incubated 20 hours at 925 ℃ after obtaining glass matrix, recording its bending strength under same condition is 190MPa, and Young's modulus is 23GPa.
Sample is soaked in constant temperature in 37 ℃, pH value transfer to 7.4 simulated body fluid, take out after 3 days, the surface is carried out microscopic appearance behind the metal spraying and is observed, the resultant of sample surfaces is carried out X-ray analysis and in conjunction with EDAX micro-area composition analytical results at D/max-2500 type superpower X-ray diffractometer on JSM-5600LV type scanning electron microscope, discovery has a large amount of fluorapatites to generate at sample surfaces, shows that this kind glass-ceramic has high biological activity.
The method that employing is holed on drilling machine is weighed the cutting ability of glass-ceramic, the boring processing conditions is: constant axial power is 392N, and High Speed Steel Bit, bit diameter are Φ 3mm, rotating speed is 400r/min, drilling time is 15s, and a drill bit is changed in hole of every brill, and the result shows, 925 ℃ the insulation 6 hours or 20 hours after, the mean depth of glass-ceramic boring is respectively 2.2mm and 2.3mm, and the no visual crackle of hole periphery, does not have and be out of shape, and has shown the good machinability of this glass-ceramic.
Embodiment 3: press SiO
245.9%, Al
2O
39.2%, MgO 11.8%, and NaF 13.1%, CaHPO
412.6%, CaCO
35.4%, CaF
22.0% batching mixing; Pour in the alumina crucible, 1500 ℃ of following meltings are 2 hours in the Si-Mo rod stove, and heat-up rate is 5 ℃/min, and fused glass is watered quenching in water, below ball milling to the 74 μ m of oven dry back; These glass powders are carried out being cast in the graphite jig after the remelting under identical condition again,, immediately graphite jig is moved in the process furnace, obtain glass matrix at 650 ℃ of insulations furnace cooling after 1 hour before this with mold heated to 500～600 ℃; Then glass matrix is warmed up to 925 ℃ of insulations 6 hours from room temperature, heat-up rate is 10 ℃/min, takes out after cooling to room temperature with the furnace.After the glass-ceramic sample processing polishing that makes, be of a size of 3 * 4 * 35mm, adopting three-point bending method test bending strength on CSS-44100 type electronic universal tester is 134MPa, Young's modulus is 12GPa.
Perhaps after obtaining glass matrix, be incubated 20 hours at 925 ℃, recording its bending strength under same condition is 153MPa, Young's modulus is 15GPa, and the glass-ceramic for preparing under the heat-treat condition is compared similarly to Example 1, and its mechanical property is further enhanced.
Sample is soaked in constant temperature in 37 ℃, pH value transfer to 7.4 simulated body fluid, take out after 3 days, the surface is carried out microscopic appearance behind the metal spraying and is observed, the resultant of sample surfaces is carried out X-ray analysis and in conjunction with EDAX micro-area composition analytical results at D/max-2500 type superpower X-ray diffractometer on JSM-5600LV type scanning electron microscope, discovery has a large amount of fluorapatites to generate at sample surfaces, shows that this kind glass-ceramic has high biological activity.
The method that employing is holed on drilling machine is weighed the cutting ability of glass-ceramic, the boring processing conditions is: constant axial power is 392N, and High Speed Steel Bit, bit diameter are Φ 3mm, rotating speed is 400r/min, drilling time is 15s, and a drill bit is changed in hole of every brill, and the result shows, 925 ℃ the insulation 6 hours or 20 hours after, the mean depth of glass-ceramic boring is respectively 2.6mm and 2.8mm, and the no visual crackle of hole periphery, does not have and be out of shape, and has shown the good machinability of this glass-ceramic.
Embodiment 4: press SiO
234.4%, Al
2O
36.9%, MgO 8.9%, and NaF 9.8%, CaHPO
425.3%, CaCO
310.7%, CaF
24.0% batching mixing; Pour in the alumina crucible, 1500 ℃ of following meltings are 2 hours in the Si-Mo rod stove, and heat-up rate is 5 ℃/min, and fused glass is watered quenching in water, below ball milling to the 74 μ m of oven dry back; These glass powders are carried out being cast in the graphite jig after the remelting under identical condition again,, immediately graphite jig is moved in the process furnace, obtain glass matrix at 650 ℃ of insulations furnace cooling after 1 hour before this with mold heated to 500～600 ℃; Then glass matrix is warmed up to 925 ℃ of insulations 6 hours from room temperature, heat-up rate is 10 ℃/min, takes out after cooling to room temperature with the furnace.After the glass-ceramic sample processing polishing that makes, be of a size of 3 * 4 * 35mm, adopting three-point bending method test bending strength on CSS-44100 type electronic universal tester is 168MPa, Young's modulus is 21GPa.
Perhaps after obtaining glass matrix, be incubated 20 hours at 925 ℃, recording its bending strength under same condition is 190MPa, Young's modulus is 23GPa, compares with the glass-ceramic of embodiment 3 preparations with embodiment 1, embodiment 2, and its mechanical property is further enhanced.
Sample is soaked in constant temperature in 37 ℃, pH value transfer to 7.4 simulated body fluid, take out after 3 days, the surface is carried out microscopic appearance behind the metal spraying and is observed, the resultant of sample surfaces is carried out X-ray analysis and in conjunction with EDAX micro-area composition analytical results at D/max-2500 type superpower X-ray diffractometer on JSM-5600LV type scanning electron microscope, discovery has a large amount of fluorapatites to generate at sample surfaces, shows that this kind glass-ceramic has high biological activity.
The method that employing is holed on drilling machine is weighed the cutting ability of glass-ceramic, the boring processing conditions is: constant axial power is 392N, and High Speed Steel Bit, bit diameter are Φ 3mm, rotating speed is 400r/min, drilling time is 15s, and a drill bit is changed in hole of every brill, and the result shows, 925 ℃ the insulation 6 hours or 20 hours after, the mean depth of glass-ceramic boring is respectively 2.2mm and 2.3mm, and the no visual crackle of hole periphery, does not have and be out of shape, and has shown the good machinability of this glass-ceramic.
Embodiment 5: press SiO
228.6%, Al
2O
35.8%, MgO 7.4%, and NaF 8.2%, CaHPO
431.6%, CaCO
313.4%, CaF
25.0% batching mixing; Pour in the alumina crucible, 1500 ℃ of following meltings are 2 hours in the Si-Mo rod stove, and heat-up rate is 5 ℃/min, and fused glass is watered quenching in water, below ball milling to the 74 μ m of oven dry back; These glass powders are carried out being cast in the graphite jig after the remelting under identical condition again,, immediately graphite jig is moved in the process furnace, obtain glass matrix at 650 ℃ of insulations furnace cooling after 1 hour before this with mold heated to 500～600 ℃; Then glass matrix is warmed up to 925 ℃ of insulations 6 hours from room temperature, heat-up rate is 10 ℃/min, takes out after cooling to room temperature with the furnace.After the glass-ceramic sample processing polishing that makes, be of a size of 3 * 4 * 35mm, adopting three-point bending method test bending strength on CSS-44100 type electronic universal tester is 191MPa, Young's modulus is 26GPa.
Perhaps after obtaining glass matrix, be incubated 20 hours at 925 ℃, recording its bending strength under same condition is 215MPa, Young's modulus is 30GPa, compares with embodiment 1, embodiment 2, embodiment 3 and the glass-ceramic of embodiment 4 preparations, and its mechanical property is further enhanced.
Sample is soaked in constant temperature in 37 ℃, pH value transfer to 7.4 simulated body fluid, take out after 3 days, the surface is carried out microscopic appearance behind the metal spraying and is observed, the resultant of sample surfaces is carried out X-ray analysis and in conjunction with EDAX micro-area composition analytical results at D/max-2500 type superpower X-ray diffractometer on JSM-5600LV type scanning electron microscope, discovery has a large amount of fluorapatites to generate at sample surfaces, as shown in Figure 3, show that this kind glass-ceramic has high biological activity.
The method that employing is holed on drilling machine is weighed the cutting ability of glass-ceramic, the boring processing conditions is: constant axial power is 392N, and High Speed Steel Bit, bit diameter are Φ 3mm, rotating speed is 400r/min, drilling time is 15s, and a drill bit is changed in hole of every brill, and the result shows, 925 ℃ the insulation 6 hours or 20 hours after, the mean depth of glass-ceramic boring is respectively 2.0mm and 2.2mm, and the no visual crackle of hole periphery, does not have and be out of shape, and has shown the good machinability of this glass-ceramic.
Claims (4)
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| CN102432164A (en) * | 2011-08-05 | 2012-05-02 | 江西理工大学 | A method for improving the structure and performance of glass-ceramics |
| CN102432182B (en) * | 2011-09-28 | 2013-11-13 | 华南理工大学 | Method for preparing machinable microcrystal glass material with high bioactivity |
| CN105936588A (en) * | 2015-02-28 | 2016-09-14 | 肖特玻璃科技(苏州)有限公司 | Glass ceramics capable of being mechanically processed and chemically tempered |
| CN109773183B (en) * | 2019-04-08 | 2021-08-27 | 长沙集智创新工业设计有限公司 | Medical metal ceramic material and preparation method thereof |
| CN110590161B (en) * | 2019-10-10 | 2022-02-15 | 西南科技大学 | A kind of method for adding V2O5 to improve the solubility of molybdenum oxide in glass ceramic solidified body |
| CN112960988A (en) * | 2021-02-02 | 2021-06-15 | 烟台正海生物科技股份有限公司 | 3D printing cuttable biological ceramic support and preparation method and application thereof |
Citations (8)
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| JPH06305827A (en) * | 1993-04-26 | 1994-11-01 | Ryoden Kasei Co Ltd | Production of glass ceramic having machinability |
| CN1280812A (en) * | 1999-07-20 | 2001-01-24 | 华西医科大学口腔医学院 | Method for making or repairing tooth crown or bridge with high-strength cuttable osmotic ceramic |
| US6280863B1 (en) * | 1997-06-12 | 2001-08-28 | Ivoclar Ag | Translucent apatite glass ceramic |
| CN1349943A (en) * | 2001-12-18 | 2002-05-22 | 清华大学 | Cutable bioactive devitrified glass and its prepn |
| CN1356289A (en) * | 2001-12-12 | 2002-07-03 | 温宁 | High-strength material with excellent machinability for repairing tooth |
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| CN1489988A (en) * | 2002-10-18 | 2004-04-21 | 中国科学院上海硅酸盐研究所 | Low-cost machinable zirconia ceramic dental restoration and its preparation method |
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2004
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| WO1993017976A1 (en) * | 1992-03-09 | 1993-09-16 | Turku Implant Team Oy | Bioactive glass as a bone substitute |
| JPH06305827A (en) * | 1993-04-26 | 1994-11-01 | Ryoden Kasei Co Ltd | Production of glass ceramic having machinability |
| US6280863B1 (en) * | 1997-06-12 | 2001-08-28 | Ivoclar Ag | Translucent apatite glass ceramic |
| CN1280812A (en) * | 1999-07-20 | 2001-01-24 | 华西医科大学口腔医学院 | Method for making or repairing tooth crown or bridge with high-strength cuttable osmotic ceramic |
| CN1356289A (en) * | 2001-12-12 | 2002-07-03 | 温宁 | High-strength material with excellent machinability for repairing tooth |
| CN1349943A (en) * | 2001-12-18 | 2002-05-22 | 清华大学 | Cutable bioactive devitrified glass and its prepn |
| CN1388077A (en) * | 2002-07-22 | 2003-01-01 | 北京盛康宁科技开发有限公司 | Method of raising bioactivity of cutable devitrified glass |
| CN1489988A (en) * | 2002-10-18 | 2004-04-21 | 中国科学院上海硅酸盐研究所 | Low-cost machinable zirconia ceramic dental restoration and its preparation method |
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| 可切削的氧化锆陶瓷牙科修复体的制备 荣天君等.无机材料学报，第18卷第2期 2003 * |
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