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CN100346742C - Method and system for non-invasive detecting intra-abdominal pressure - Google Patents

Method and system for non-invasive detecting intra-abdominal pressure Download PDF

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CN100346742C
CN100346742C CNB2004100091666A CN200410009166A CN100346742C CN 100346742 C CN100346742 C CN 100346742C CN B2004100091666 A CNB2004100091666 A CN B2004100091666A CN 200410009166 A CN200410009166 A CN 200410009166A CN 100346742 C CN100346742 C CN 100346742C
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pressure
abdominal pressure
intra
displacement
abdominal
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CN1582848A (en
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白净
毛羽
徐灿星
应葵
李霞
孙剑
张永红
李彤
张立军
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Tsinghua University
Beijing Tongren Hospital
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Beijing Tongren Hospital
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Abstract

腹内压的无创检测方法及其系统属于医学测量领域,其特征在于:它由压力传感器和位移传感器构成压力-位移传感器组合,通过数据测量和处理系统测量腹外压变化时产生的压力传感器输出电压变化量,再根据通过临床实验采集数据并由数学拟合方法得到的腹内压-腹外压转换公式计算出腹内压的值,它具有无创伤且临床应用方便的优点;并提出了相应的腹内压无创检测用的硬件结构。

Figure 200410009166

The non-invasive detection method and system of intra-abdominal pressure belong to the field of medical measurement, and it is characterized in that it consists of a pressure sensor and a displacement sensor to form a pressure-displacement sensor combination, and the pressure sensor output generated when the external pressure of the abdomen is measured is measured by a data measurement and processing system Then calculate the value of intra-abdominal pressure according to the conversion formula of intra-abdominal pressure-external abdominal pressure obtained by data collected through clinical experiments and obtained by mathematical fitting method, which has the advantages of non-invasive and convenient clinical application; and put forward Corresponding hardware structure for non-invasive detection of intra-abdominal pressure.

Figure 200410009166

Description

腹内压的无创检测方法及其系统Non-invasive detection method and system for intra-abdominal pressure

技术领域technical field

腹内压无创检测方法及其系统属于医用测量方法及装置领域,主要用于腹内压的间接无创测量。The non-invasive detection method and system for intra-abdominal pressure belong to the field of medical measurement methods and devices, and are mainly used for indirect non-invasive measurement of intra-abdominal pressure.

背景技术Background technique

腹腔室隔综合征(ACS)定义为腹腔内压急剧升高引起一系列病理生理改变所形成的一种临床综合征。根据腹腔内压力升高速度和病程进展情况可分为急性ACS和慢性ACS(如肿瘤、腹水、妊娠),临床上所指的ACS均系急性ACS,常发生于创伤后或腹部手术后。当腹内压急剧增高到一定程度时,如不及时采取措施,将会对肺、肾以及心脏等多个器官造成损害,甚至会导致多个器官衰竭以至休克和死亡。Abdominal compartment syndrome (ACS) is defined as a clinical syndrome formed by a series of pathophysiological changes caused by a sharp increase in intra-abdominal pressure. According to the speed of intra-abdominal pressure rise and the progress of the disease, it can be divided into acute ACS and chronic ACS (such as tumor, ascites, pregnancy). The clinically referred to ACS are all acute ACS, which often occur after trauma or abdominal surgery. When the intra-abdominal pressure increases sharply to a certain level, if measures are not taken in time, it will cause damage to multiple organs such as the lungs, kidneys, and heart, and even lead to multiple organ failure, shock and death.

目前,腹腔减压术是对ACS治疗的唯一方法,而手术时机对腹腔减压术的效果影响很大,因此,确定最佳手术时间显得尤为重要,这就要求必须正确、及时了解并跟踪ACS的病况。由于腹内压(IAP)的大小及变化能准确反映ACS的状况,临床上一直采用其作为病况判断及决定手术时间的重要指标。At present, abdominal decompression is the only way to treat ACS, and the timing of operation has a great influence on the effect of abdominal decompression. Therefore, it is particularly important to determine the best operation time, which requires correct and timely understanding and tracking of ACS. condition. Since the size and change of intra-abdominal pressure (IAP) can accurately reflect the condition of ACS, it has been used clinically as an important indicator for judging the condition and deciding the time of operation.

目前腹内压的测量方法可分为直接测压和间接测压两种方法。前者是直接置管于腹腔内,然后连接压力传感器,或在腹腔镜手术中通过气腹机对腹压连续监测。间接测压法是通过测量下腔静脉压力、胃内压力及膀胱内压来间接反映腹腔内压力。At present, the measurement methods of intra-abdominal pressure can be divided into direct pressure measurement and indirect pressure measurement. The former is to directly place a tube in the abdominal cavity, and then connect a pressure sensor, or continuously monitor the abdominal pressure through an insufflation machine during laparoscopic surgery. Indirect manometry is to indirectly reflect intra-abdominal pressure by measuring inferior vena cava pressure, intragastric pressure and intravesical pressure.

虽然目前对于膀胱压是否准确地反映腹腔内压尚有争议,其中由于膀胱测压法相对准确、简单且损伤性较小,因此作为一个客观指标,膀胱压在腹内压测量中使用最为普遍。该方法首先被Kron等提出并描述,测量方法很简单,患者仰卧位,将引流管与Foley导尿管连接,向膀胱内注入50ml等渗盐水,然后通过三通连接水压计,以耻骨联合为零平面,水柱高度即为腹腔内压力。Although it is still controversial whether bladder pressure accurately reflects intra-abdominal pressure, bladder pressure is the most commonly used in intra-abdominal pressure measurement as an objective indicator because cystometry is relatively accurate, simple and less invasive. This method was first proposed and described by Kron et al. The measurement method is very simple. The patient is placed in the supine position, the drainage tube is connected to the Foley catheter, 50ml of isotonic saline is injected into the bladder, and then a water pressure gauge is connected through a three-way connection to the pubic symphysis. is the zero plane, and the height of the water column is the intra-abdominal pressure.

在临床上,测量膀胱压的过程虽然属于微创,但它依然会对病人心理、生理造成一定伤害,甚至可能会造成感染或针刺伤害,引起不良后果,因此,研究并寻求一种准确且无创的腹内压测量方法十分必要,具有重要的科学意义和广泛的实用价值。In clinical practice, although the process of measuring bladder pressure is minimally invasive, it will still cause certain psychological and physical harm to the patient, and may even cause infection or acupuncture injury, causing adverse consequences. Therefore, it is necessary to study and seek an accurate and Non-invasive intra-abdominal pressure measurement method is very necessary, has important scientific significance and extensive practical value.

发明内容Contents of the invention

本发明的目的在于提供一种腹内压无创检测方法及装置,它通过腹外压力、位移与腹内压之间的函数关系,从腹外压的测量结果计算得到腹内压的数值,从而间接实现腹内压的无创检测,能大大减轻患者和医生的负担。The purpose of the present invention is to provide a non-invasive detection method and device for intra-abdominal pressure, which calculates the value of intra-abdominal pressure from the measurement results of external pressure through the functional relationship between external pressure, displacement and intra-abdominal pressure, thereby Indirect non-invasive detection of intra-abdominal pressure can greatly reduce the burden on patients and doctors.

考虑到将压力传感器与位移传感器进行合理组装,可以实现压力与位移之间的正比关系,如果将位移进行分档,那么利用该压力-位移传感器装置就可测得一定位移下的腹外压力,而此数据与腹内压之间存在相关性,如果建立起此二者之间的函数关系,我们就能由该函数关系通过外腹压测量值间接得到腹内压的数值,从而真正实现腹内压的无创测量。若在固定位移的情况下测量腹外压的变化,或者在固定腹外压的情况下测量位移的变化,则均可以得到腹内压的发展状况,从而保证对病人病况进行实时跟踪。Considering that the pressure sensor and the displacement sensor are properly assembled, the proportional relationship between pressure and displacement can be realized. If the displacement is divided into stages, the pressure-displacement sensor device can be used to measure the external pressure under a certain displacement. There is a correlation between this data and the intra-abdominal pressure. If a functional relationship between the two is established, we can indirectly obtain the value of the intra-abdominal pressure from the functional relationship through the measured value of the external abdominal pressure, so as to truly realize the abdominal pressure. Non-invasive measurement of internal pressure. If the change of external abdominal pressure is measured under the condition of fixed displacement, or the change of displacement is measured under the condition of fixed external pressure, the development status of intra-abdominal pressure can be obtained, so as to ensure the real-time tracking of the patient's condition.

本发明所述的方法,其特征在于:它依次含有以下步骤:The method of the present invention is characterized in that: it contains the following steps successively:

(1)向计算机输入腹外压的采样数据以及下述腹外压-腹内压转换公式:(1) Input the sampling data of external abdominal pressure and the following external pressure-intra-abdominal pressure conversion formula into the computer:

             y=ax+by=ax+b

其中,x为腹外压,y为腹内压,a、b分别为待定系数,对于不同型号的压力-位移传感器,a、b的具体值可事先通过数据拟合的方法求得;Among them, x is the external pressure of the abdomen, y is the intra-abdominal pressure, and a and b are undetermined coefficients respectively. For different types of pressure-displacement sensors, the specific values of a and b can be obtained in advance by the method of data fitting;

(2)采用由压力传感器和位移传感器机械连接构成的压力-位移传感器组合,再按以下步骤测量腹外压:(2) Use a pressure-displacement sensor combination composed of a pressure sensor and a displacement sensor mechanically connected, and then measure the external abdominal pressure according to the following steps:

(2.1)把压力传感器滑杆的端部紧贴被测试者的腹部,即位移、腹外压的初始值均为零,再缓缓推进滑杆,使其端部紧压腹部,至某个固定位移;(2.1) Put the end of the slide bar of the pressure sensor close to the abdomen of the subject, that is, the initial values of displacement and external pressure are both zero, and then slowly push the slide bar so that the end presses the abdomen tightly to a certain value. fixed displacement;

(2.2)在该位移下,压力传感器将此时的腹外压转化为电压值;(2.2) Under this displacement, the pressure sensor converts the external abdominal pressure at this time into a voltage value;

(3)该电压值输入到一个放大倍数与腹外压测量范围相对应的电压放大电路;(3) The voltage value is input to a voltage amplifying circuit whose magnification is corresponding to the measuring range of the external abdominal pressure;

(4)电压放大电路的输出信号经A/D转换后送往CPU,算出相应的腹内压并加以显示;同时也经USB采集卡送往PC机储存。(4) The output signal of the voltage amplifying circuit is sent to the CPU after A/D conversion, and the corresponding intra-abdominal pressure is calculated and displayed; at the same time, it is also sent to the PC for storage through the USB acquisition card.

本发明所述的系统,其特征在于:它含有:System of the present invention is characterized in that: it contains:

压力-位移传感器,它由压力传感器和位移传感器机械连接构成;A pressure-displacement sensor, which is composed of a pressure sensor and a displacement sensor mechanically connected;

电压放大电路,它的输入端和上述压力传感器的数据输出端相连;A voltage amplifying circuit, the input end of which is connected to the data output end of the above-mentioned pressure sensor;

A/D转换器,它的输入端与上述电压放大电路的输出端相连;A/D converter, its input end is connected with the output end of above-mentioned voltage amplifying circuit;

CPU,它的信号输入端与上述A/D转换器的输出端相连,而该CPU的信号输出端又与一个显示电路的信号输入端相连;CPU, its signal input end is connected with the output end of above-mentioned A/D converter, and the signal output end of this CPU is connected with the signal input end of a display circuit;

USB采集卡,它的信号输入端与上述电压放大电路的输出端相连,而USB采集卡的输出端则与一个PC机相连。The signal input end of the USB acquisition card is connected with the output end of the voltage amplifying circuit, and the output end of the USB acquisition card is connected with a PC.

该方法将免除有创测量中可能造成的感染,使得临床医生可在病人无任何创伤的条件下实现病况跟踪和及时监护,并对手术时间作出最佳判断,而且该方法操作简单方便,更适于临床应用。This method will avoid the infection that may be caused by the invasive measurement, so that the clinician can realize the tracking and timely monitoring of the patient's condition without any trauma, and make the best judgment on the operation time, and the method is simple, convenient and more suitable in clinical application.

附图说明Description of drawings

图1.压力-位移传感器的结构示意图。Figure 1. Schematic diagram of the structure of the pressure-displacement sensor.

图2.压力-位移传感器的使用示意图:Figure 2. Schematic diagram of the use of pressure-displacement sensors:

A-压力传感器的滑杆紧贴被测试者腹部;A- The slide bar of the pressure sensor is close to the abdomen of the subject;

B-压力传感器的滑杆挤压被测试者腹部。The slide bar of the B-pressure sensor squeezes the abdomen of the subject.

图3.腹内压无创检测方法的计算流程图。Figure 3. Calculation flow chart of the non-invasive detection method of intra-abdominal pressure.

图4.腹内压无创检测系统的电路原理框图。Figure 4. Schematic block diagram of the circuit for the non-invasive detection system of intra-abdominal pressure.

图5.实施例的位移-腹外压曲线。Figure 5. Displacement-External Abdominal Pressure Curve of Example.

图6.实施例的腹外压-腹内压曲线。Figure 6. The external abdominal pressure-intra-abdominal pressure curve of the embodiment.

具体实施方式Detailed ways

请见图1:6是压力传感器,1是它的滑杆,3是位移传感器,2是3的滑动头,5是圆筒。位移传感器3用螺钉4固定在圆筒5的内壁,滑杆1和滑动头5楔接,而压力传感器6则穿过圆筒5的上下两端。Please see Figure 1: 6 is the pressure sensor, 1 is its sliding rod, 3 is the displacement sensor, 2 is the sliding head of 3, and 5 is the cylinder. The displacement sensor 3 is fixed on the inner wall of the cylinder 5 with the screw 4 , the sliding rod 1 and the sliding head 5 are wedged, and the pressure sensor 6 passes through the upper and lower ends of the cylinder 5 .

先用滑杆1紧贴被测试者腹部,再把位移传感器滑动头缓缓推进至一个固定值,此推进过程中引起腹外压的变化,从而引起压力传感器输出电压的变化,测得图5所示的曲线。再由本发明所述的系统,得到图6所示曲线,并在显示电路上输出显示。First use the slide bar 1 to cling to the subject’s abdomen, and then slowly advance the sliding head of the displacement sensor to a fixed value. During this advance process, the external pressure of the abdomen will change, which will cause the output voltage of the pressure sensor to change. The measured value is shown in Figure 5 the curve shown. Then by the system of the present invention, the curve shown in Fig. 6 is obtained, and output and displayed on the display circuit.

以下为本发明的一个实施例:采用YH-4型压力传感器,采用滑动变阻器为位移传感器,通过数据拟合得到腹外压-腹内压转换公式系数a=110.0746,b=-3.4664,所测得的腹内压与常用的膀胱压测量值列表并比较如下:   年龄   性别   身高(cm)   体重(kg)   腹外压(mv)   膀胱压测量值(cm水柱)   腹内压计算值(cm水柱)   误差   病况   58   男   173   53   100   7.5   7.54   0.04   腹腔粘液腺癌   38   男   168   55   68   4.0   4.02   0.02   脑外伤   71   女   155   42.5   90   6.5   6.44   0.06   梗阻性黄疸,胰头癌 The following is an embodiment of the present invention: adopt the YH-4 type pressure sensor, adopt the sliding rheostat as the displacement sensor, obtain the external pressure-intra-abdominal pressure conversion formula coefficient a=110.0746, b=-3.4664 by data fitting, the measured The obtained intra-abdominal pressure is tabulated and compared with commonly used bladder pressure measurements as follows: age gender height (cm) weight(kg) Abdominal pressure (mv) Bladder pressure measurement (cm water column) Calculated value of intra-abdominal pressure (cm water column) error condition 58 male 173 53 100 7.5 7.54 0.04 peritoneal mucinous adenocarcinoma 38 male 168 55 68 4.0 4.02 0.02 traumatic brain injury 71 female 155 42.5 90 6.5 6.44 0.06 Obstructive jaundice, carcinoma of the head of the pancreas

Claims (1)

1、腹内压无创检测系统,其特征在于,它含有:1. The intra-abdominal pressure non-invasive detection system is characterized in that it contains: 压力—位移传感器,由压力传感器和位移传感器机械连接构成,按如下步骤将腹压转换为位移:The pressure-displacement sensor is composed of a pressure sensor and a displacement sensor mechanically connected, and converts abdominal pressure into displacement according to the following steps: 首先,把压力传感器滑杆的端部紧贴被测试者的腹部,即位移、腹外压的初始值均为零,再缓缓推进滑杆,使其端部紧压腹部,至某个固定位移;First, put the end of the pressure sensor slide bar close to the subject's abdomen, that is, the initial values of displacement and external pressure are both zero, and then slowly push the slide bar so that the end presses the abdomen tightly to a fixed position. displacement; 其次,在该位移下,压力传感器将此时的腹外压转化为电压值;Secondly, under this displacement, the pressure sensor converts the external abdominal pressure at this time into a voltage value; 第三,该电压值输入到一个放大倍数与腹外压测量范围相对应的电压放大电路;电压放大电路,输入端和上述压力传感器的数据输出端相连;Third, the voltage value is input to a voltage amplifying circuit with a magnification corresponding to the measurement range of the external abdominal pressure; the voltage amplifying circuit has an input terminal connected to the data output terminal of the above-mentioned pressure sensor; A/D转换器,输入端与上述电压放大电路的输出端相连;A/D converter, the input terminal is connected with the output terminal of the above-mentioned voltage amplifying circuit; CPU,信号输入端与上述A/D转换器的输出端相连,而该CPU的信号输出端又与一个显示电路的信号输入端相连;根据下述公式y=ax+b将腹外压转换为腹内压,其中x为腹外压,y为腹内压,a、b为待定系数,对于不同型号的压力—位移传感器,a、b的具体值可事先通过数据拟合的方法求得;CPU, the signal input end is connected with the output end of above-mentioned A/D converter, and the signal output end of this CPU is connected with the signal input end of a display circuit again; According to following formula y=ax+b, external abdominal pressure is converted into Intra-abdominal pressure, where x is external abdominal pressure, y is intra-abdominal pressure, and a and b are undetermined coefficients. For different types of pressure-displacement sensors, the specific values of a and b can be obtained in advance through data fitting methods; USB采集卡,信号输入端与上述电压放大电路的输出端相连,而USB采集卡的输出端则与一个PC机相连。In the USB acquisition card, the signal input end is connected with the output end of the above-mentioned voltage amplifying circuit, and the output end of the USB acquisition card is connected with a PC.
CNB2004100091666A 2004-06-03 2004-06-03 Method and system for non-invasive detecting intra-abdominal pressure Expired - Fee Related CN100346742C (en)

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