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CN100342894C - A Chinese medicine for treating liver disease - Google Patents

A Chinese medicine for treating liver disease Download PDF

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Publication number
CN100342894C
CN100342894C CNB2005100415335A CN200510041533A CN100342894C CN 100342894 C CN100342894 C CN 100342894C CN B2005100415335 A CNB2005100415335 A CN B2005100415335A CN 200510041533 A CN200510041533 A CN 200510041533A CN 100342894 C CN100342894 C CN 100342894C
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radix
gram
liver
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CN1879781A (en
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何慕周
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Abstract

The present invention relates to a Chinese medicine for treating liver diseases, which is prepared from the following Chinese herbal medicines in proportion: 260 to 350g of radix codonopsitis, 50 to 120g of anthriscus sylvestris, 260 to 340g of stir-fired largehead atractylodes rhizome, 350 to 550g of poria from Yunnan of China, 20 to 50g of stir-fired immature orange fruit, 20 to 30g of common aucklandia root, 120 to 220g of common yam rhizome, 180 to 220g of palmleaf raspberry fruit, 150 to 260g of stringy stonecrop herb, 150 to 260g of isatis root, 100 to 220g of dandelion, 300 to 500g of red peony root, 250 to 300g of stir-baked Radix Paeoniae Alba and 40 to 60g of bupleurum root. According to the pathogenic mechanism of hepatosis, the present invention adopts a traditional Chinese medicinal prescription which can mainly replenish qi to invigorate the spleen, supplement the liver and the kidney, disperse stagnated liver qi for promoting bile flow and activate blood circulation to dissipate blood stasis, thereby realizing the functions of adjusting and increasing the immunizing power of organisms, improving the liver functions and making hepatosis stabilized, improved and cured. The prescription of the present invention takes the principle of protecting the liver, and has obvious therapeutic effect on various kinds of hepatosis, particularly on chronic hepatitis B, liver cirrhosis and hepatogenic ascites.

Description

A kind of Chinese medicine for the treatment of hepatopathy
Affiliated technical field
The present invention relates to a kind of medicine for the treatment of hepatopathy, exactly, is a kind of Chinese medicine for the treatment of hepatopathys such as viral hepatitis, liver cirrhosis, hepatic ascites.
Background technology
Hepatitis is as the term suggests be exactly that inflammatory reaction has taken place liver.Because the inner impercipience nerve of liver so pain is not too serious, if check that through " liver living tissue's puncture " hepatic tissue section that obtains is placed on microscopically and sees, can see that there is leukocyte infiltration in the inflammation district.The symptom of hepatitis mainly shows as, heating, weak, inappetence, feel sick, abdominal distention, diarrhoea, yellowish urine, skin and sclera (white of the eye) jaundice, the hepatic region is uncomfortable or pain etc.Chronic hepatitis has that nasal mucosa is hemorrhage, gingival hemorrhage, both legs swelling.Hepatitis gravis can occur that listlessness is depressed, dysphoria, sleep inversion, stupor etc.Hepatitis is commonly encountered diseases, frequently-occurring disease.Be divided into first type virus (HAV) hepatitis, B virus (HBV) hepatitis and third type virus (HCV) hepatitis etc. by morbidity cause virus, wherein, the hepatitis B incidence is the most serious.According to the statistics made by the departments concerned, China hepatitis B patient has 3,000 ten thousand at present, and hepatitis B virus carriers is 1.2 hundred million.Along with the quickening of people's rhythm of life, exceedingly drink, cause the alcoholic hepatitis sickness rate to increase, and ethanol not only can quicken chronic hepatitis such as hepatitis B greatly and changes into the process of liver cirrhosis, and can make healthy people directly drink into alcoholic cirrhosis, or cause hepatocarcinoma.Bad living habit and use medicine improperly causes the hepatitis due to medicine sickness rate also constantly to rise.
The doctor trained in Western medicine hepatopathy is normally checked what index was implemented to treat according to liver.With the treatment hepatitis B is example, and doctor trained in Western medicine is reducing serum alanine aminotransferase, and catharsis has harmful effect to liver but fall the enzyme medicine mostly, and the transaminase can rebound after the drug withdrawal, as re-uses and fall the enzyme medicine and then can cause the catharsis function of liver further to be destroyed.The patient who has paddy acyl transaminase rising can occur after using and falling the enzyme medicine, or bilirubin value seriously raises, hepatic fibrosis occurring is the liver cirrhosis omen, in this case, the enzyme medicine falls if continue to use doctor trained in Western medicine, liver function is made the matter worse beyond doubt, finally may cause liver cirrhosis, hepatic ascites even cancerate.To liver cirrhosis, hepatic ascites disease, doctor trained in Western medicine adopts diuretic or instillation albumin therapy usually, but general curative effect is not good enough, and the expense costliness.
Summary of the invention
For overcoming the defective of existing liver disease method, through exploring for many years, the present invention discloses a kind of easy to use, Chinese prescription that therapeutic effect is good, and the technical solution adopted for the present invention to solve the technical problems is:
1, it is to be made by the Chinese herbal medicine of following consumption proportion:
The 260-350 of Radix codonopsis pilosulae (Radix Codonopsis) gram, GUANG Radix Notoginseng 50-120 gram, Rhizoma Atractylodis Macrocephalae (parched) 260-340 gram, PORIA from Yunnan of China 350-550 gram, Fructus Aurantii Immaturus (parched) 20-50 gram, Radix Aucklandiae 20-30 gram, Rhizoma dioscoreae 120-220 gram, Fructus Rubi 180-220 gram, Herba Sedi Sarmentosi 150-260 gram, Radix Isatidis 150-260 gram, Herba Taraxaci 100-220 gram, Radix Paeoniae Rubra 300-500 gram, Radix Paeoniae Alba (parched) 250-300 gram, Radix Bupleuri 40-60 gram.
2, its optimization prescription is the Chinese herbal medicine by following consumption proportion:
Radix codonopsis pilosulae's 300 grams, GUANG Radix Notoginseng 100 grams, Rhizoma Atractylodis Macrocephalae (parched) 300 grams, PORIA from Yunnan of China 500 grams, Fructus Aurantii Immaturus (parched) 50 grams, the Radix Aucklandiae 30 grams, Rhizoma dioscoreae 200 grams, Fructus Rubi 200 grams, Herba Sedi Sarmentosi 200 grams, Radix Isatidis 200 grams, Herba Taraxaci 200 grams, Radix Paeoniae Rubra 400 grams, Radix Paeoniae Alba (parched) 300 grams, Radix Bupleuri 60 grams.
Chinese medicine of the present invention is traditional honeyed pill, and the Chinese herbal medicine of above-mentioned prescription is ground into superfine powder, the mixing of sieving, and refined honey is made.
The present invention be directed to the hepatopathy pathogeny, selected prescription is based on replenishing QI to invigorate the spleen, liver and kidney tonifying, depressed liver-energy dispersing and function of gallbladder promoting, blood circulation promoting and blood stasis dispelling, reaches to adjust to improve body immunity, improve liver function, makes hepatopathy stable good then control.
The present invention selects Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Fructus Rubi, Poria for use, is monarch drug, replenishing QI to invigorate the spleen, liver and kidney tonifying, wherein:
Radix Codonopsis is the root of campanulaceae plant Radix Codonopsis, contain Saponin, alkaloid, sucrose, glucose, inulin, starch, mucus and resin etc., Radix codonopsis pilosulae (Radix Codonopsis) contains volatile oil, scutellarein glucosid, micro-alkaloid, polysaccharide, inulin, Saponin, and nature and flavor are sweet, flat, has invigorating middle warmer, QI invigorating, an effect of promoting the production of body fluid.
The Rhizoma Atractylodis Macrocephalae is a feverfew Rhizoma Atractylodis Macrocephalae rhizome, contains volatile oil, atractylol, atractylone, vitamin etc., and property bitter but sweet flavor, temperature have spleen reinforcing, stomach reinforcing, dampness and middle effect.
Fructus Rubi is green fruits such as rosaceous plant Fructus Rubi, rubus coreanus, contain organic acid, saccharide and a small amount of vitamin C, the sweet acid of nature and flavor, flat has invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs, the effect that makes eye bright are controlled diseases such as sexual impotence, seminal emission, frequency of micturition, asthenia, order be dark.
Rhizoma Dioscoreae has another name called RHIIZOMA DIOSCOREAE frOm Henan of China, Rhizoma dioscoreae, tuber for Dioscoreaceae plant Rhizoma Dioscoreae, contain Saponin, phlegmatic temperament, choline, starch, glycoprotein and free amino acid etc., have spleen invigorating, tonifying the lung, reinforce the kidney, beneficial smart function, control diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, quench one's thirst, seminal emission, leukorrhagia, frequent micturition.
Poria is the dry sclerotia of Polyporaceae plant Poria, contain pachyman, acetyl pachymic acid, natural gum, chitin etc., the property slightly sweet flavor, flat, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming effect, diseases such as controlling dysuria, edema distension, phlegm retention cough with dyspnea, have loose bowels, drench worm, be forgetful.
It is ministerial drug that the present invention selects Radix Notoginseng for use, blood circulation promoting and blood stasis dispelling and the absurd row of not hyperamization, because:
Radix Notoginseng is the root of Araliaceae Panax pseudoginseng, contains Saponin, arasaponin and glucose etc., and property sweet and slightly bitter taste, temperature have hemostasis, dissipating blood stasis, detumescence, analgesic therapy function, controls haematemesis, hemoptysis, has blood in stool, disease such as traumatic hemorrhage, carbuncle pain.
It is adjuvant drug that the present invention selects Fructus Aurantii Immaturus, the Radix Aucklandiae, Radix Paeoniae for use, and Fructus Aurantii Immaturus, the circulation of qi promoting of the broken knot of the Radix Aucklandiae to separate the fraud that causes abdominal distention of qi-benefiting and spleen-strengthening drug, help the merit of Poria circulation of qi promoting diuresis, and the Radix Paeoniae Rubra removing heat from blood and promoting blood circulation helps the Radix Notoginseng blood stasis dispelling, helps the Herba Artemisiae Scopariae function of gallbladder promoting to fall Huang, wherein:
Fructus Aurantii Immaturus is the young fruit of cloud savoury herb Fructus Ponciri Trifoliatae (Fructus Ponciri Trifoliatae Immaturus), Citrus aurantium Linn. or fragrant circle, contains volatile oil, and contains flavonoid glycoside more, and the nature and flavor bitter cold has dispelling the stagnated QI, diffusing painful abdominal mass, rushes down expectorant, removing food stagnancy effect, controls diseases such as distension and fullness of the chest and abdomen, the thoracic obstruction, accumulation of phlegm in the hypochondrium, edema, food stagnation, constipation.
The Radix Aucklandiae is the root of feverfew Saussurea lappa Clarke, vladimiria denticulata Ling, Radix Vladimiriae etc., contains volatile oil, and nature and flavor are arduous, warm, have promoting the circulation of QI to relieve pain, warming middle-JIAO for easing the stomach effect, controls the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain, vomits, has loose bowels etc.
Radix Paeoniae Rubra is the root of the wild Radix Paeoniae of ranunculaceae plant, Paeonia obovata Maxim., river Radix Paeoniae Rubra etc., contains paeoniflorin, and nature and flavor are bitter, flat, have clots absorbing, pain relieving, removing heat from blood, detumescence effect.
It is messenger drug that the present invention selects Herba Sedi Sarmentosi, Radix Isatidis, Herba Taraxaci, Radix Bupleuri for use, and liver heat removing is fallen enzyme and protected stomach, wherein:
Herba Sedi Sarmentosi is the herb of Crassulaceae plant Herba Sedi, and property slightly sweet flavor, cold have heat clearing away, detumescence, detoxicating functions, control laryngopharynx swelling and pain, carbuncle, burn due to hot liquid or fire, Serpentis, insect bite etc.
Radix Isatidis is root or the acanthaceous vegetable acanthaceous indigo rhizome and the root of cruciferae isatis and careless Folium Isatidis, contain indigo glycoside, sitosterol, isatin etc., nature and flavor hardship, cold has heat clearing away, detoxifcation, removing heat from blood effect, controls influenza, encephalitis b, pneumonia, erysipelas, pyretic toxicity and sends out diseases such as speckle, pharyngalgia, skin ulcer rash.
Herba Taraxaci is the whole herb with root of feverfew Herba Taraxaci, contains taraxasterol, choline, inulin and pectin, and property bitter but sweet flavor, cold has heat-clearing and toxic substances removing, diuresis mass-dissipating efficacy, diseases such as treatment carbuncle toxin, cat fever, gastritis, hepatitis, cholecystitis.
Radix Bupleuri is the root of samphire Radix Bupleuri, Radix Bupeuri Scorzonerfolii. etc., contain volatile oil, bupleurumol, oleic acid, linolenic acid, glucose, saikoside etc., nature and flavor hardship, cold have reconciling superficies and interior, soothing the liver, yang invigorating effect, control alternate attack of chill and fever, fullness in the chest costalgia, bitter taste deafness, malaria etc.
The obtained beneficial effect of the present invention is:
1, the present invention is according to the pathogeny of hepatopathy, the Chinese prescription that adopts, and it is main having replenishing QI to invigorate the spleen, liver and kidney tonifying, depressed liver-energy dispersing and function of gallbladder promoting, blood circulation promoting and blood stasis dispelling, reaches to adjust to improve body immunity, improve liver function, makes hepatopathy stable good then control.
2, prescription of the present invention is a principle to protect the liver, and specially the treating the liver disease is applied widely, and various hepatopathys especially chronic viral hepatitis B, liver cirrhosis and hepatic ascites are had obvious curative effects;
3, result of use of the present invention:
Clinical treatment 680 routine hepatopaths with screening are example, hepatitis B patient 520 examples wherein, liver cirrhosis 90 examples, hepatic ascites 70 examples.Using method: the present invention is made honeyed pill, and for oral administration, lunch and supper were taken in last hour, and it is a course of treatment that chronic viral hepatitis B is taken 30 days continuously; It is a course of treatment that liver cirrhosis is taken 30 days; It is a course of treatment that hepatic ascites takes 35.Above-mentioned patient by age reaches the state of an illness and uses the present invention to treat one or two course of treatment continuously, carries out observation of curative effect.408 routine patients recovery from illness is arranged, and follow up a case by regular visits to after 1 year and there is no the recidivist, 68 examples have significant curative effect, and 102 examples have certain curative effect, invalid 102 examples, and total effective rate reaches 85.0%, and cure rate reaches 60%.
The specific embodiment
Below in conjunction with embodiment the present invention is further described.
Embodiment 1:
Take off the row raw material: Radix codonopsis pilosulae's 300 grams, GUANG Radix Notoginseng 100 grams, Rhizoma Atractylodis Macrocephalae (parched) 300 grams, PORIA from Yunnan of China 500 grams, Fructus Aurantii Immaturus (parched) 50 grams, the Radix Aucklandiae 30 grams, Rhizoma dioscoreae 200 grams, Fructus Rubi 200 grams, Herba Sedi Sarmentosi 200 grams, Radix Isatidis 200 grams, Herba Taraxaci 200 grams, Radix Paeoniae Rubra 400 grams, Radix Paeoniae Alba (parched) 300 grams, Radix Bupleuri 60 grams are ground into superfine powder respectively, sieving is mixed, and makes honeyed pill in 1: 1 ratio and refined honey, and the bottling sealing is stand-by.
Embodiment 2:
The Chinese medicine for oral administration of present embodiment is to be made by the Chinese herbal medicine of following consumption proportion: get Radix codonopsis pilosulae's 350 grams, GUANG Radix Notoginseng 120 grams, Rhizoma Atractylodis Macrocephalae (parched) 340 grams, PORIA from Yunnan of China 550 grams, Fructus Aurantii Immaturus (parched) 50 grams, the Radix Aucklandiae 30 grams, Rhizoma dioscoreae 220 grams, Fructus Rubi 220 grams, Herba Sedi Sarmentosi 260 grams, Radix Isatidis 260 grams, Herba Taraxaci 220 grams, Radix Paeoniae Rubra 500 grams, Radix Paeoniae Alba (parched) 300,60 parts of Radix Bupleuri, its preparation method is with embodiment 1.
Embodiment 3:
The Chinese medicine for oral administration of present embodiment is to be made by the Chinese herbal medicine of following consumption proportion: Radix Codonopsis 260 grams, GUANG Radix Notoginseng 50 grams, Rhizoma Atractylodis Macrocephalae (parched) 260 grams, PORIA from Yunnan of China 350 grams, Fructus Aurantii Immaturus (parched) 20 grams, the Radix Aucklandiae 20 grams, Rhizoma dioscoreae 120 grams, Fructus Rubi 180 grams, Herba Sedi Sarmentosi 150 grams, Radix Isatidis 150 grams, Herba Taraxaci 100 grams, Radix Paeoniae Rubra 300 grams, Radix Paeoniae Alba (parched) 250 grams, Radix Bupleuri 40 grams, its preparation method is with embodiment 1.

Claims (2)

1, a kind of Chinese medicine for the treatment of hepatopathy is characterized in that: it is to be made by the Chinese herbal medicine of following consumption proportion:
Radix Codonopsis 260-350 gram, GUANG Radix Notoginseng 50-120 gram, Rhizoma Atractylodis Macrocephalae (parched) 260-340 gram, PORIA from Yunnan of China 350-550 gram, Fructus Aurantii Immaturus (parched) 20-50 gram, Radix Aucklandiae 20-30 gram, Rhizoma dioscoreae 120-220 gram, Fructus Rubi 180-220 gram, Herba Sedi Sarmentosi 150-260 gram, Radix Isatidis 150-260 gram, Herba Taraxaci 100-220 gram, Radix Paeoniae Rubra 300-500 gram, Radix Paeoniae Alba (parched) 250-300 gram, Radix Bupleuri 40-60 gram.
2, according to the Chinese medicine of the described treatment hepatopathy of claim 1, it is characterized in that: it is to be made by the Chinese herbal medicine of following consumption proportion:
Radix codonopsis pilosulae's 300 grams, GUANG Radix Notoginseng 100 grams, Rhizoma Atractylodis Macrocephalae (parched) 300 grams, PORIA from Yunnan of China 500 grams, Fructus Aurantii Immaturus (parched) 50 grams, the Radix Aucklandiae 30 grams, Rhizoma dioscoreae 200 grams, Fructus Rubi 200 grams, Herba Sedi Sarmentosi 200 grams, Radix Isatidis 200 grams, Herba Taraxaci 200 grams, Radix Paeoniae Rubra 400 grams, Radix Paeoniae Alba (parched) 300 grams, Radix Bupleuri 60 grams.
CNB2005100415335A 2005-08-16 2005-08-16 A Chinese medicine for treating liver disease Expired - Fee Related CN100342894C (en)

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CN102341114A (en) 2009-03-03 2012-02-01 加拿大瑞发生物科技制药集团 Herbal extract composition for prevention and treatment of influenza
CN102727633B (en) * 2012-07-20 2014-03-19 成都中医药大学 Pharmaceutical composition for treating chronic hepatitis B and preparation method and application thereof
CN106068667B (en) 2015-07-13 2019-09-10 海能达通信股份有限公司 A kind of LTE group system identical networking resource regulating method and device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1113779A (en) * 1994-06-17 1995-12-27 殷广全 Anti- hepatitis B preparation
CN1137383A (en) * 1995-06-02 1996-12-11 丁殿利 Yigan Kangyangsan powder for curing hepatitis B
CN1253013A (en) * 1999-10-25 2000-05-17 车兴泉 Medicine for treating hepatism and its preparing process

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1113779A (en) * 1994-06-17 1995-12-27 殷广全 Anti- hepatitis B preparation
CN1137383A (en) * 1995-06-02 1996-12-11 丁殿利 Yigan Kangyangsan powder for curing hepatitis B
CN1253013A (en) * 1999-10-25 2000-05-17 车兴泉 Medicine for treating hepatism and its preparing process

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