CN100337669C - Externally applied medicine for curing pain and process for preparing the same - Google Patents
Externally applied medicine for curing pain and process for preparing the same Download PDFInfo
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- CN100337669C CN100337669C CNB2005100031655A CN200510003165A CN100337669C CN 100337669 C CN100337669 C CN 100337669C CN B2005100031655 A CNB2005100031655 A CN B2005100031655A CN 200510003165 A CN200510003165 A CN 200510003165A CN 100337669 C CN100337669 C CN 100337669C
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- pain
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- 239000003814 drug Substances 0.000 title claims abstract description 34
- 238000004519 manufacturing process Methods 0.000 title 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims abstract description 12
- 241000723346 Cinnamomum camphora Species 0.000 claims abstract description 12
- 229960000846 camphor Drugs 0.000 claims abstract description 12
- 229930008380 camphor Natural products 0.000 claims abstract description 12
- 229940079593 drug Drugs 0.000 claims abstract description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 20
- 239000000706 filtrate Substances 0.000 claims description 15
- 238000001914 filtration Methods 0.000 claims description 10
- 238000002360 preparation method Methods 0.000 claims description 9
- 238000005303 weighing Methods 0.000 claims description 7
- LSPHULWDVZXLIL-UHFFFAOYSA-N (+/-)-Camphoric acid Chemical class CC1(C)C(C(O)=O)CCC1(C)C(O)=O LSPHULWDVZXLIL-UHFFFAOYSA-N 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 5
- 238000010298 pulverizing process Methods 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 13
- 230000017531 blood circulation Effects 0.000 abstract description 4
- 210000003205 muscle Anatomy 0.000 abstract description 3
- 210000002435 tendon Anatomy 0.000 abstract description 3
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 230000000638 stimulation Effects 0.000 abstract description 2
- 241000173529 Aconitum napellus Species 0.000 abstract 1
- 241000759271 Alangium Species 0.000 abstract 1
- 241001419717 Anisodus luridus Species 0.000 abstract 1
- 241000721153 Chloranthus japonicus Species 0.000 abstract 1
- 206010030113 Oedema Diseases 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 239000002994 raw material Substances 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 229940098465 tincture Drugs 0.000 description 4
- 208000014674 injury Diseases 0.000 description 3
- 206010050031 Muscle strain Diseases 0.000 description 2
- 206010034464 Periarthritis Diseases 0.000 description 2
- 206010041591 Spinal osteoarthritis Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 208000036319 cervical spondylosis Diseases 0.000 description 2
- 230000005714 functional activity Effects 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 230000002040 relaxant effect Effects 0.000 description 2
- 208000005801 spondylosis Diseases 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 230000008736 traumatic injury Effects 0.000 description 2
- 206010033474 Pain of skin Diseases 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses an external application drug for treating pain, which comprises the crude drugs of the following proportion by weight: 10 to 20 portions of anisodus luridus, 10 to 20 portions of Chinese alangium root, 10 to 20 portions of henry chloranthus herb, 10 to 20 portions of common monkshood root, 10 to 20 portions of RADIX ACONITI KUSNEZIFFII and 3 to 5 portions of camphor tablet. The drugs are combined, which enables each drug efficacy to generate synergistic effect. Thus, the pain is effectively treated. The present invention can expel wind, clear away cold, relax muscles and tendons, promote blood circulation, reduce edema and alleviate pain, and has the advantages of good treating effect, high efficiency, no toxic side effect and no stimulation for skin.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of pain, relating in particular to a kind of is the medicine for external use of primary raw material preparation with the Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Background technology
By rheumatism, rheumatoid, scapulohumeral periarthritis, cervical spondylosis, lumbar muscle strain, caused pain symptom such as traumatic injury, comparatively common in daily life.For this class treatment of diseases, Chinese and western medicine common method and medicine are a lot, but curative effect is undesirable, and often with untoward reaction, the toxic and side effects that has is also very big during medication and after the drug withdrawal.At present Chinese medicine comprises two kinds of medicine for external use and oral medicine, and oral medicine has certain toxic and side effects to human body, and gastrointestinal tract is also had certain stimulation.The externally applied ointment class is pasted for a long time in the part can cause certain injury to skin, and general medicine for external use is difficult for absorbing, and curative effect is not obvious.
Summary of the invention
The object of the present invention is to provide a kind of expelling wind and cold, relaxing muscles and tendons to promote blood circulation, reducing swelling and alleviating pain, therapeutic effect is good, effective percentage is high, have no side effect and to the external used medicine of the non-stimulated treatment pain of skin.
Another object of the present invention is to provide the preparation method of this external used medicine.
The consumption of drug component of the present invention is also groped to sum up to draw through the inventor in a large number, and each amounts of components is for all to have better curative effect in the following weight parts scope:
Radix Anisodi Acutanguli 10-20 part Radix Alangii 10-20 part Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 10-20 part
Radix Aconiti 10-20 part Radix Aconiti Kusnezoffii 10-20 part camphor tablet 3-5 part
The preparation method of medicine activity component of the present invention is:
(1) it is standby to take by weighing camphor tablet in the formula ratio ratio;
(2) take by weighing all the other five kinds of pulverizing medicinal materials in the formula ratio ratio, add three times of 70% soak with ethanol 15-20 days, filter filtrate for later use;
(3) in last step medicated powder after filtering, added again three times of 50% soak with ethanol 15-20 days, filter filtrate for later use;
(4) soak the filtrate mixing that after-filtration obtains with twice, the piece that camphorates again mixes stirring evenly promptly.
The active ingredient of medicine gained of the present invention can add conventional adjuvant, makes various exterior-applied formulations according to a conventional method.
Medicine of the present invention makes the direct osmotic absorption of medicine, forms higher drug level at affected part, make that therapeutic effect is good, effective percentage is high, can improve the local organization blood circulation, the absorption of softening local fiber adhesion and promotion adhesion, thereby the recovery of promotion function of joint; Has tangible expelling wind and cold, relaxing muscles and tendons to promote blood circulation, the effect of reducing swelling and alleviating pain.
The specific embodiment
Below further set forth the beneficial effect of medicine of the present invention by clinical observation on the therapeutic effect test.
(1) physical data
Whole case 890 examples, male's 390 examples wherein, women's 500 examples, maximum 72 years old age, minimum 25 years old, 45 years old mean age.
(2) Therapeutic Method
The tincture that the treatment group adopts the embodiment of the invention 1 to make.
The cleaning local skin, taking liquid dabs pain part (scope of applying medicinal lotion or ointment is big slightly than the pain scope), then by gently to the heavy massage part, the heating get final product, treat every day 3 times, 7 is a course of treatment, treats 3 courses of treatment altogether.
(3) therapeutic effect
Curative effect judging standard:
Produce effects: pain disappears, and functional activity recovers.
Effectively: pain obviously alleviates, and functional activity partly recovers.
Invalid: curative effect is not obvious
| The sick kind | The example number | Produce effects | Effectively | Invalid | Total effective rate |
| Scapulohumeral periarthritis | 150 | 70 | 74 | 6 | 96％ |
| Lumbar muscle strain | 130 | 68 | 54 | 8 | 94％ |
| Cervical spondylosis | 180 | 82 | 86 | 12 | 93％ |
| Traumatic injury | 210 | 100 | 82 | 8 | 96％ |
| Rheumatic arthritis | 220 | 140 | 72 | 8 | 96％ |
Embodiment 1
Take by weighing raw material by following amount:
Radix Anisodi Acutanguli 15g Radix Alangii 15g Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 15g
Radix Aconiti 15g Radix Aconiti Kusnezoffii 15g camphor tablet 4g
Preparation method is:
(1) it is standby to get camphor tablet;
(2) all the other five kinds of pulverizing medicinal materials add three times of 70% soak with ethanol 15-20 days, filter filtrate for later use;
(3) in last step medicated powder after filtering, added again three times of 50% soak with ethanol 15-20 days, filter filtrate for later use;
(4) soak the filtrate mixing that after-filtration obtains with twice, the piece that camphorates again mixes stirring evenly the tincture that promptly gets the invention medicine.
Embodiment 2
Take by weighing raw material by following amount:
Radix Anisodi Acutanguli 20g Radix Alangii 20g Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 20g
Radix Aconiti 20g Radix Aconiti Kusnezoffii 20g camphor tablet 5g
Preparation method is:
(1) it is standby to get camphor tablet;
(2) all the other five kinds of pulverizing medicinal materials add three times of 70% soak with ethanol 15-20 days, filter filtrate for later use;
(3) in last step medicated powder after filtering, added again three times of 50% soak with ethanol 15-20 days, filter filtrate for later use;
(4) soak the filtrate mixing that after-filtration obtains with twice, the piece that camphorates again mixes stirring evenly the tincture that promptly gets the invention medicine.
Embodiment 3
Take by weighing raw material by following amount:
Radix Anisodi Acutanguli 10g Radix Alangii 10g piece watt 10g
Radix Aconiti 10g Radix Aconiti Kusnezoffii 10g camphor tablet 3g
Preparation method is:
(1) it is standby to get camphor tablet;
(2) all the other five kinds of pulverizing medicinal materials add three times of 70% soak with ethanol 15-20 days, filter filtrate for later use;
(3) in last step medicated powder after filtering, added again three times of 50% soak with ethanol 15-20 days, filter filtrate for later use;
(4) soak the filtrate mixing that after-filtration obtains with twice, the piece that camphorates again mixes stirring evenly the tincture that promptly gets the invention medicine.
Claims (3)
1, a kind of external used medicine for the treatment of pain is characterized in that it is made by following raw medicaments in portion by weight:
Radix Anisodi Acutanguli 10-20 part Radix Alangii 10-20 part Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 10-20 part
Radix Aconiti 10-20 part Radix Aconiti Kusnezoffii 10-20 part camphor tablet 3-5 part.
2, the external used medicine of treatment pain as claimed in claim 1 is characterized in that the consumption of each crude drug is:
15 parts of 15 parts of Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae)s of 15 parts of Radix Alangiis of Radix Anisodi Acutanguli
4 parts of 15 parts of camphor tablets of 15 parts of Radix Aconiti Kusnezoffiis of Radix Aconiti.
3, treat the preparation method of the external used medicine of pain as claimed in claim 1 or 2, it is characterized in that:
(1) it is standby to take by weighing camphor tablet by described weight proportion;
(2) take by weighing all the other five kinds of pulverizing medicinal materials by described weight proportion, add three times of 70% soak with ethanol 15-20 days, filter filtrate for later use;
(3) in last step medicated powder after filtering, added again three times of 50% soak with ethanol 15-20 days, filter filtrate for later use;
(4) soak the filtrate mixing that after-filtration obtains with twice, the piece that camphorates again mixes stirring evenly promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100031655A CN100337669C (en) | 2005-08-17 | 2005-08-17 | Externally applied medicine for curing pain and process for preparing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100031655A CN100337669C (en) | 2005-08-17 | 2005-08-17 | Externally applied medicine for curing pain and process for preparing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1733150A CN1733150A (en) | 2006-02-15 |
| CN100337669C true CN100337669C (en) | 2007-09-19 |
Family
ID=36075905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100031655A Expired - Fee Related CN100337669C (en) | 2005-08-17 | 2005-08-17 | Externally applied medicine for curing pain and process for preparing the same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100337669C (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1459310A (en) * | 2002-05-24 | 2003-12-03 | 黄本云 | medicine for treating hyperosteogeny |
-
2005
- 2005-08-17 CN CNB2005100031655A patent/CN100337669C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1459310A (en) * | 2002-05-24 | 2003-12-03 | 黄本云 | medicine for treating hyperosteogeny |
Non-Patent Citations (1)
| Title |
|---|
| 自拟镇痛消突酊热敷配合功能锻炼治疗腰椎间盘突出症 王纪云 姜玲 余华忠，中医正骨，第14卷第8期 2002 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1733150A (en) | 2006-02-15 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |