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CL2018001135A1 - Métodos de tratamiento usando anticuerpos anti - il 17a/17f (il-17a/f) - Google Patents

Métodos de tratamiento usando anticuerpos anti - il 17a/17f (il-17a/f)

Info

Publication number
CL2018001135A1
CL2018001135A1 CL2018001135A CL2018001135A CL2018001135A1 CL 2018001135 A1 CL2018001135 A1 CL 2018001135A1 CL 2018001135 A CL2018001135 A CL 2018001135A CL 2018001135 A CL2018001135 A CL 2018001135A CL 2018001135 A1 CL2018001135 A1 CL 2018001135A1
Authority
CL
Chile
Prior art keywords
antibodies
treatment methods
treatment
dermatological
psoriasis
Prior art date
Application number
CL2018001135A
Other languages
English (en)
Inventor
Sophie Glatt
Lucian Ionescu
Margaret Jones
Ruth Oliver
Stevan Graham Shaw
Foteini Strimenopoulou
Venkata Pavan Kumar Vajjah
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57223670&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2018001135(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of CL2018001135A1 publication Critical patent/CL2018001135A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La invención se refiere a usos terapéuticos de moléculas de anticuerpo que tienen especificidad por determinantes antigénicos tanto de IL-17A como de IL-17F en el tratamiento de enfermedades dermatológicas y reumatológicas, tales como psoriasis, artritis psoriásica y espondiloartritis axial.
CL2018001135A 2015-10-27 2018-04-27 Métodos de tratamiento usando anticuerpos anti - il 17a/17f (il-17a/f) CL2018001135A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562246989P 2015-10-27 2015-10-27
US201662303230P 2016-03-03 2016-03-03
US201662346826P 2016-06-07 2016-06-07
US201662405546P 2016-10-07 2016-10-07

Publications (1)

Publication Number Publication Date
CL2018001135A1 true CL2018001135A1 (es) 2019-05-10

Family

ID=57223670

Family Applications (3)

Application Number Title Priority Date Filing Date
CL2018001135A CL2018001135A1 (es) 2015-10-27 2018-04-27 Métodos de tratamiento usando anticuerpos anti - il 17a/17f (il-17a/f)
CL2021002815A CL2021002815A1 (es) 2015-10-27 2021-10-26 Usos de anticuerpos anti-il-17a/f (divisional 2018-01135)
CL2021002816A CL2021002816A1 (es) 2015-10-27 2021-10-26 Usos de anticuerpos anti-il-17a/f (divisional 2018-01135)

Family Applications After (2)

Application Number Title Priority Date Filing Date
CL2021002815A CL2021002815A1 (es) 2015-10-27 2021-10-26 Usos de anticuerpos anti-il-17a/f (divisional 2018-01135)
CL2021002816A CL2021002816A1 (es) 2015-10-27 2021-10-26 Usos de anticuerpos anti-il-17a/f (divisional 2018-01135)

Country Status (15)

Country Link
US (3) US11492396B2 (es)
EP (1) EP3368570A1 (es)
JP (5) JP6931648B2 (es)
KR (2) KR20180067676A (es)
CN (2) CN116059350A (es)
AU (2) AU2016347471B2 (es)
BR (1) BR112018008075A2 (es)
CA (1) CA3001260A1 (es)
CL (3) CL2018001135A1 (es)
CO (1) CO2018004493A2 (es)
IL (1) IL258515A (es)
MX (4) MX2018005031A (es)
RU (1) RU2754683C2 (es)
SG (2) SG11201802887PA (es)
WO (1) WO2017072183A1 (es)

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* Cited by examiner, † Cited by third party
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EP4467565A3 (en) 2016-12-21 2025-03-12 Amgen Inc. Anti-tnf alpha antibody formulations
US20200277369A1 (en) * 2017-11-20 2020-09-03 Novartis Ag Method of treating hidradentitis suppurativa with il-17 antagonists
GB201719447D0 (en) * 2017-11-23 2018-01-10 Ucb Biopharma Sprl Pharmaceutical composition
WO2021050563A1 (en) * 2019-09-09 2021-03-18 The Rockefeller University Antibody treatment for lesional tissue of hidradenitis suppurativa
CN116685605A (zh) * 2020-12-17 2023-09-01 上海华奥泰生物药业股份有限公司 靶向il-17a和il-36r的双特异性抗体及其应用
EP4471427A1 (en) * 2023-05-31 2024-12-04 Centre Hospitalier Universitaire De Nice Biomarker for spondyloarthitis diagnostic and response to treatment

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Also Published As

Publication number Publication date
CN108350068A (zh) 2018-07-31
MX2022009380A (es) 2022-09-07
KR20240156437A (ko) 2024-10-29
JP2023025019A (ja) 2023-02-21
JP7176044B2 (ja) 2022-11-21
AU2016347471A1 (en) 2018-05-10
US11492396B2 (en) 2022-11-08
JP2021130707A (ja) 2021-09-09
RU2018118029A3 (es) 2020-09-17
US20190292255A1 (en) 2019-09-26
EP3368570A1 (en) 2018-09-05
MX2022009379A (es) 2022-09-07
WO2017072183A1 (en) 2017-05-04
AU2016347471B2 (en) 2023-08-03
JP2021119168A (ja) 2021-08-12
CL2021002816A1 (es) 2022-07-29
MX2023004315A (es) 2023-05-08
SG11201802887PA (en) 2018-05-30
US20230279093A1 (en) 2023-09-07
CL2021002815A1 (es) 2022-07-29
BR112018008075A2 (pt) 2018-12-04
JP2018535961A (ja) 2018-12-06
AU2023255037A1 (en) 2023-11-16
CN116059350A (zh) 2023-05-05
CA3001260A1 (en) 2017-05-04
MX2018005031A (es) 2018-06-13
SG10202112586WA (en) 2021-12-30
IL258515A (en) 2018-05-31
CO2018004493A2 (es) 2018-11-30
RU2754683C2 (ru) 2021-09-06
JP6931750B2 (ja) 2021-09-08
US20230287100A1 (en) 2023-09-14
RU2018118029A (ru) 2019-12-04
JP6931648B2 (ja) 2021-09-08
JP2025037926A (ja) 2025-03-18
KR20180067676A (ko) 2018-06-20

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