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CL2008003007A1 - Un micro chip con capas de ceramicas de coccion conjunta a baja temperatura (ltcc) formando una camara de reaccion, anillos conductores que rodean a la camara de reaccion y un calentador que suministra calor a los anillos, el metodo de fabricacion del micro chip y un micro dispositivo de reaccion en cadena de polimerasa (pcr). - Google Patents

Un micro chip con capas de ceramicas de coccion conjunta a baja temperatura (ltcc) formando una camara de reaccion, anillos conductores que rodean a la camara de reaccion y un calentador que suministra calor a los anillos, el metodo de fabricacion del micro chip y un micro dispositivo de reaccion en cadena de polimerasa (pcr).

Info

Publication number
CL2008003007A1
CL2008003007A1 CL2008003007A CL2008003007A CL2008003007A1 CL 2008003007 A1 CL2008003007 A1 CL 2008003007A1 CL 2008003007 A CL2008003007 A CL 2008003007A CL 2008003007 A CL2008003007 A CL 2008003007A CL 2008003007 A1 CL2008003007 A1 CL 2008003007A1
Authority
CL
Chile
Prior art keywords
reaction chamber
layers
heater
microchip
rings
Prior art date
Application number
CL2008003007A
Other languages
English (en)
Inventor
Krishna Kumar Kishore
Bhaskaran Nair Chandrasekhar
Venkata Subbarao Pillarisetti
Jagannath Manjula
Chennakrishnaiah Shilpa
prakash jayaraman Ravi
Kaipa Narasimha Sankaranand
Mahiladevi Radhakrishnan Renjith
Viswanathan Sathyadeep
Original Assignee
Bigtec Private Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bigtec Private Ltd filed Critical Bigtec Private Ltd
Publication of CL2008003007A1 publication Critical patent/CL2008003007A1/es

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0848Specific forms of parts of containers
    • B01L2300/0851Bottom walls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

SE DESCRIBE UN MICRO DISPOSITIVO DE REACCIÓN EN CADENA DE POLIMERASA (PCR), QUE COMPRENDE UN MICRO CHIP HECHO DE CAPAS DE LTCC, QUE COMPRENDE UNA CÁMARA DE REACCIÓN FORMADA POR MÚLTIPLES CAPAS PARA LA CARGA DE UNA MUESTRA, ANILLOS CONDUCTORES QUE RODEAN LA CÁMARA DE REACCIÓN Y UN CALENTADOR<br /> INCORPORADO EN POR LO MENOS UNA CAPA PARA SUMINISTRAR CALOR A LOS ANILLOS CONDUCTORES, UN SENSOR DE TEMPERATURA INCORPORADO EN EL MICRO CHIP, UN CIRCUITO DE CONTROL PARA CONTROLAR EL CALENTADOR EN BASE A LA LECTURA DEL SENSOR DE TEMPERATURA Y UN SISTEMA ÓPTICO PARA DETECTAR LA SEÑAL DE FLUORESCENCIA A PARTIR<br /> DE LA MUESTRA, EN DONDE EL MÉTODO DE FABRICACIÓN DEL MICRO CHIP COMPRENDE LOS PASOS DE DISPONER DE MÚLTIPLES CAPAS HECHAS DE CAPAS DE CERÁMICAS DE COCCIÓN CONJUNTA A BAJA TEMPERATURA (LTCC) Y QUE TIENE UN POZO PARA FORMAR UNA CÁMARA DE REACCIÓN, EN DONDE LA CÁMARA ES RODEADA POR ANILLOS CONDUCTORES, COLOCAR POR LO MENOS UNA CAPA DE LTCC QUE COMPRENDE UN CALENTADOR DEBAJO LA CÁMARA, COLOCAR UNA O VARIAS CAPAS DE CONDUCTOR ENTRE EL CALENTADOR Y LA CÁMARA DE REACCIÓN, E INTERCONECTAR LAS CAPAS PARA FORMAR EL MICRO CHIP.<br />  
CL2008003007A 2007-10-12 2008-10-10 Un micro chip con capas de ceramicas de coccion conjunta a baja temperatura (ltcc) formando una camara de reaccion, anillos conductores que rodean a la camara de reaccion y un calentador que suministra calor a los anillos, el metodo de fabricacion del micro chip y un micro dispositivo de reaccion en cadena de polimerasa (pcr). CL2008003007A1 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN2311CH2007 2007-10-12
IN2312CH2007 2007-10-12
IN2314CH2007 2007-10-12
IN2313CH2007 2007-10-12
IN2328CH2007 2007-10-15

Publications (1)

Publication Number Publication Date
CL2008003007A1 true CL2008003007A1 (es) 2009-10-02

Family

ID=40549716

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2008003008A CL2008003008A1 (es) 2007-10-12 2008-10-10 Un micro dispositivo portatil de reaccion en cadena de polimerasa (pcr) basado en un micro chip de ceramica de coccion conjunta de baja temperatura (ltcc) que comprende camara de reaccion, calentador, control de temperatura del calentador, deteccion optica de interfaz de comunicacion, y el metodo para monitorearlo y controlarlo.
CL2008003007A CL2008003007A1 (es) 2007-10-12 2008-10-10 Un micro chip con capas de ceramicas de coccion conjunta a baja temperatura (ltcc) formando una camara de reaccion, anillos conductores que rodean a la camara de reaccion y un calentador que suministra calor a los anillos, el metodo de fabricacion del micro chip y un micro dispositivo de reaccion en cadena de polimerasa (pcr).

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL2008003008A CL2008003008A1 (es) 2007-10-12 2008-10-10 Un micro dispositivo portatil de reaccion en cadena de polimerasa (pcr) basado en un micro chip de ceramica de coccion conjunta de baja temperatura (ltcc) que comprende camara de reaccion, calentador, control de temperatura del calentador, deteccion optica de interfaz de comunicacion, y el metodo para monitorearlo y controlarlo.

Country Status (33)

Country Link
US (2) US9044754B2 (es)
EP (2) EP2212691B1 (es)
JP (2) JP5167362B2 (es)
KR (2) KR101571038B1 (es)
CN (2) CN101868721B (es)
AP (2) AP2683A (es)
AR (2) AR070659A1 (es)
AU (2) AU2008310525B2 (es)
BR (2) BRPI0817985B1 (es)
CA (2) CA2702549C (es)
CL (2) CL2008003008A1 (es)
CO (2) CO6270381A2 (es)
CY (2) CY1121430T1 (es)
DK (2) DK2212692T3 (es)
EA (2) EA027913B1 (es)
ES (2) ES2728957T3 (es)
HR (2) HRP20190871T1 (es)
HU (2) HUE043078T2 (es)
IL (2) IL204997A (es)
LT (2) LT2212692T (es)
MA (2) MA31803B1 (es)
MX (2) MX2010003978A (es)
MY (2) MY166386A (es)
NZ (2) NZ584594A (es)
PE (2) PE20090965A1 (es)
PL (2) PL2212692T3 (es)
PT (2) PT2212692T (es)
SI (2) SI2212692T1 (es)
TN (2) TN2010000157A1 (es)
TR (1) TR201903278T4 (es)
TW (2) TWI448686B (es)
WO (2) WO2009047804A2 (es)
ZA (1) ZA201002536B (es)

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