CL2008003007A1 - Un micro chip con capas de ceramicas de coccion conjunta a baja temperatura (ltcc) formando una camara de reaccion, anillos conductores que rodean a la camara de reaccion y un calentador que suministra calor a los anillos, el metodo de fabricacion del micro chip y un micro dispositivo de reaccion en cadena de polimerasa (pcr). - Google Patents
Un micro chip con capas de ceramicas de coccion conjunta a baja temperatura (ltcc) formando una camara de reaccion, anillos conductores que rodean a la camara de reaccion y un calentador que suministra calor a los anillos, el metodo de fabricacion del micro chip y un micro dispositivo de reaccion en cadena de polimerasa (pcr).Info
- Publication number
- CL2008003007A1 CL2008003007A1 CL2008003007A CL2008003007A CL2008003007A1 CL 2008003007 A1 CL2008003007 A1 CL 2008003007A1 CL 2008003007 A CL2008003007 A CL 2008003007A CL 2008003007 A CL2008003007 A CL 2008003007A CL 2008003007 A1 CL2008003007 A1 CL 2008003007A1
- Authority
- CL
- Chile
- Prior art keywords
- reaction chamber
- layers
- heater
- microchip
- rings
- Prior art date
Links
- 238000003752 polymerase chain reaction Methods 0.000 title abstract 3
- 239000000919 ceramic Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000010304 firing Methods 0.000 title 1
- 239000004020 conductor Substances 0.000 abstract 1
- 238000010411 cooking Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0851—Bottom walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Optical Measuring Cells (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
SE DESCRIBE UN MICRO DISPOSITIVO DE REACCIÓN EN CADENA DE POLIMERASA (PCR), QUE COMPRENDE UN MICRO CHIP HECHO DE CAPAS DE LTCC, QUE COMPRENDE UNA CÁMARA DE REACCIÓN FORMADA POR MÚLTIPLES CAPAS PARA LA CARGA DE UNA MUESTRA, ANILLOS CONDUCTORES QUE RODEAN LA CÁMARA DE REACCIÓN Y UN CALENTADOR<br /> INCORPORADO EN POR LO MENOS UNA CAPA PARA SUMINISTRAR CALOR A LOS ANILLOS CONDUCTORES, UN SENSOR DE TEMPERATURA INCORPORADO EN EL MICRO CHIP, UN CIRCUITO DE CONTROL PARA CONTROLAR EL CALENTADOR EN BASE A LA LECTURA DEL SENSOR DE TEMPERATURA Y UN SISTEMA ÓPTICO PARA DETECTAR LA SEÑAL DE FLUORESCENCIA A PARTIR<br /> DE LA MUESTRA, EN DONDE EL MÉTODO DE FABRICACIÓN DEL MICRO CHIP COMPRENDE LOS PASOS DE DISPONER DE MÚLTIPLES CAPAS HECHAS DE CAPAS DE CERÁMICAS DE COCCIÓN CONJUNTA A BAJA TEMPERATURA (LTCC) Y QUE TIENE UN POZO PARA FORMAR UNA CÁMARA DE REACCIÓN, EN DONDE LA CÁMARA ES RODEADA POR ANILLOS CONDUCTORES, COLOCAR POR LO MENOS UNA CAPA DE LTCC QUE COMPRENDE UN CALENTADOR DEBAJO LA CÁMARA, COLOCAR UNA O VARIAS CAPAS DE CONDUCTOR ENTRE EL CALENTADOR Y LA CÁMARA DE REACCIÓN, E INTERCONECTAR LAS CAPAS PARA FORMAR EL MICRO CHIP.<br />
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2311CH2007 | 2007-10-12 | ||
IN2312CH2007 | 2007-10-12 | ||
IN2314CH2007 | 2007-10-12 | ||
IN2313CH2007 | 2007-10-12 | ||
IN2328CH2007 | 2007-10-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2008003007A1 true CL2008003007A1 (es) | 2009-10-02 |
Family
ID=40549716
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008003008A CL2008003008A1 (es) | 2007-10-12 | 2008-10-10 | Un micro dispositivo portatil de reaccion en cadena de polimerasa (pcr) basado en un micro chip de ceramica de coccion conjunta de baja temperatura (ltcc) que comprende camara de reaccion, calentador, control de temperatura del calentador, deteccion optica de interfaz de comunicacion, y el metodo para monitorearlo y controlarlo. |
CL2008003007A CL2008003007A1 (es) | 2007-10-12 | 2008-10-10 | Un micro chip con capas de ceramicas de coccion conjunta a baja temperatura (ltcc) formando una camara de reaccion, anillos conductores que rodean a la camara de reaccion y un calentador que suministra calor a los anillos, el metodo de fabricacion del micro chip y un micro dispositivo de reaccion en cadena de polimerasa (pcr). |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2008003008A CL2008003008A1 (es) | 2007-10-12 | 2008-10-10 | Un micro dispositivo portatil de reaccion en cadena de polimerasa (pcr) basado en un micro chip de ceramica de coccion conjunta de baja temperatura (ltcc) que comprende camara de reaccion, calentador, control de temperatura del calentador, deteccion optica de interfaz de comunicacion, y el metodo para monitorearlo y controlarlo. |
Country Status (33)
Country | Link |
---|---|
US (2) | US9044754B2 (es) |
EP (2) | EP2212691B1 (es) |
JP (2) | JP5167362B2 (es) |
KR (2) | KR101571038B1 (es) |
CN (2) | CN101868721B (es) |
AP (2) | AP2683A (es) |
AR (2) | AR070659A1 (es) |
AU (2) | AU2008310525B2 (es) |
BR (2) | BRPI0817985B1 (es) |
CA (2) | CA2702549C (es) |
CL (2) | CL2008003008A1 (es) |
CO (2) | CO6270381A2 (es) |
CY (2) | CY1121430T1 (es) |
DK (2) | DK2212692T3 (es) |
EA (2) | EA027913B1 (es) |
ES (2) | ES2728957T3 (es) |
HR (2) | HRP20190871T1 (es) |
HU (2) | HUE043078T2 (es) |
IL (2) | IL204997A (es) |
LT (2) | LT2212692T (es) |
MA (2) | MA31803B1 (es) |
MX (2) | MX2010003978A (es) |
MY (2) | MY166386A (es) |
NZ (2) | NZ584594A (es) |
PE (2) | PE20090965A1 (es) |
PL (2) | PL2212692T3 (es) |
PT (2) | PT2212692T (es) |
SI (2) | SI2212692T1 (es) |
TN (2) | TN2010000157A1 (es) |
TR (1) | TR201903278T4 (es) |
TW (2) | TWI448686B (es) |
WO (2) | WO2009047804A2 (es) |
ZA (1) | ZA201002536B (es) |
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