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CH649533A5 - Picolilamide idrata di acido isoftalico ad azione antiaggregante piastrinica, antitrombinica ed anticoagulante e procedimento per la sua preparazione. - Google Patents

Picolilamide idrata di acido isoftalico ad azione antiaggregante piastrinica, antitrombinica ed anticoagulante e procedimento per la sua preparazione. Download PDF

Info

Publication number
CH649533A5
CH649533A5 CH2531/81A CH253181A CH649533A5 CH 649533 A5 CH649533 A5 CH 649533A5 CH 2531/81 A CH2531/81 A CH 2531/81A CH 253181 A CH253181 A CH 253181A CH 649533 A5 CH649533 A5 CH 649533A5
Authority
CH
Switzerland
Prior art keywords
picotamide
monohydrate
water
anhydrous
blood
Prior art date
Application number
CH2531/81A
Other languages
English (en)
Italian (it)
Inventor
Giovanni Orzalesi
Ivo Volpato
Original Assignee
Manetti & Italo Brit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manetti & Italo Brit filed Critical Manetti & Italo Brit
Publication of CH649533A5 publication Critical patent/CH649533A5/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CH2531/81A 1980-04-23 1981-04-07 Picolilamide idrata di acido isoftalico ad azione antiaggregante piastrinica, antitrombinica ed anticoagulante e procedimento per la sua preparazione. CH649533A5 (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48494/80A IT1143942B (it) 1980-04-23 1980-04-23 Picolilammide idrata di acido isoftalico ad azione antiaggregante piastrinica antitrombinica ed anticoagulante e procedimento per la sua preparazione

Publications (1)

Publication Number Publication Date
CH649533A5 true CH649533A5 (it) 1985-05-31

Family

ID=11266904

Family Applications (1)

Application Number Title Priority Date Filing Date
CH2531/81A CH649533A5 (it) 1980-04-23 1981-04-07 Picolilamide idrata di acido isoftalico ad azione antiaggregante piastrinica, antitrombinica ed anticoagulante e procedimento per la sua preparazione.

Country Status (23)

Country Link
JP (1) JPS6043063B2 (de)
AT (1) AT375645B (de)
AU (1) AU537921B2 (de)
BE (1) BE888528A (de)
CA (1) CA1129419A (de)
CH (1) CH649533A5 (de)
DD (1) DD158397A5 (de)
DE (1) DE3113150C2 (de)
DK (1) DK155735C (de)
ES (1) ES501470A0 (de)
FI (1) FI74951C (de)
FR (1) FR2481283B1 (de)
GB (1) GB2080288B (de)
IE (1) IE51218B1 (de)
IL (1) IL62509A (de)
IT (1) IT1143942B (de)
NL (1) NL186860C (de)
NO (1) NO154193C (de)
NZ (1) NZ196677A (de)
OA (1) OA06795A (de)
PT (1) PT72899B (de)
SE (1) SE438674B (de)
ZA (1) ZA812362B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1214915B (it) * 1985-10-10 1990-01-31 Manetti & Roberts Italo Brit Derivato dell'acido 4-metossiisoftalico con attivita'farmacologica in disordini tromboembolici e procedimento per la sua preparazione
US5227492A (en) * 1988-01-20 1993-07-13 Yamanouchi Pharmaceutical Co., Ltd. Diurea derivatives useful as medicaments and processes for the preparation thereof
TW200900393A (en) * 2007-05-21 2009-01-01 Dybly Ag Salts of picotamide
CN111154114A (zh) * 2019-12-31 2020-05-15 肇庆学院 一种基于5-乙氧基间苯二甲酸的锌(ⅱ)金属有机配位化合物及其制备方法
CN111154113A (zh) * 2019-12-31 2020-05-15 肇庆学院 一种基于双核钴(ⅱ)的金属有机配合物及其制备方法
CN112159347B (zh) * 2020-10-27 2022-06-07 常州工程职业技术学院 吡考他胺的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL149810B (nl) * 1969-04-21 1976-06-15 Lilly Co Eli Werkwijze ter bereiding van een farmaceutisch preparaat door kristallijn cefalexine in een voor therapeutische toediening geschikte vorm te brengen, gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van voor bovengenoemde toepassing geschikt cefalexine.
IT1016005B (it) * 1970-07-01 1977-05-30 Manetti & Roberts Italo Brit Picolilamidi dell acido 4 idrossi isoftalico e suoi derivati e relativo procedimento di prepara zione
US3973026A (en) * 1975-02-05 1976-08-03 Societa Italo-Britannica L. Manetti-H. Roberts & C. Inhibitor of blood plate aggregation

Also Published As

Publication number Publication date
IE51218B1 (en) 1986-11-12
FI74951B (fi) 1987-12-31
IE810808L (en) 1981-10-23
FR2481283A1 (de) 1981-10-30
CA1129419A (en) 1982-08-10
JPS5735566A (en) 1982-02-26
DD158397A5 (de) 1983-01-12
IL62509A0 (en) 1981-05-20
DE3113150C2 (de) 1985-05-15
IL62509A (en) 1984-03-30
PT72899B (en) 1982-04-05
DK155735B (da) 1989-05-08
SE438674B (sv) 1985-04-29
IT8048494A0 (it) 1980-04-23
NO811360L (no) 1981-10-26
ZA812362B (en) 1982-04-28
AU537921B2 (en) 1984-07-19
NL8102016A (nl) 1981-11-16
FI811257L (fi) 1981-10-24
ES8203086A1 (es) 1982-02-16
FR2481283B1 (de) 1985-01-04
GB2080288B (en) 1984-02-01
SE8101963L (sv) 1981-10-24
NL186860C (nl) 1991-03-18
ES501470A0 (es) 1982-02-16
PT72899A (en) 1981-05-01
BE888528A (nl) 1981-08-17
FI74951C (fi) 1988-04-11
NO154193C (no) 1986-08-06
GB2080288A (en) 1982-02-03
DE3113150A1 (de) 1982-01-28
AT375645B (de) 1984-08-27
NZ196677A (en) 1983-05-31
JPS6043063B2 (ja) 1985-09-26
DK155735C (da) 1989-10-02
OA06795A (fr) 1982-12-31
AU6931081A (en) 1981-10-29
NO154193B (no) 1986-04-28
NL186860B (nl) 1990-10-16
DK177281A (da) 1981-10-24
IT1143942B (it) 1986-10-29
ATA166481A (de) 1984-01-15

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Legal Events

Date Code Title Description
PUE Assignment

Owner name: INTERNATIONAL LICENSING & SERVICES B.V.

PUE Assignment

Owner name: SANDOZ AG

PL Patent ceased