CH546768A - PROCESS FOR THE PREPARATION OF 2- (5-NITRO-2-IMIDAZOLYL) BENZIMIDAZOLES. - Google Patents

PROCESS FOR THE PREPARATION OF 2- (5-NITRO-2-IMIDAZOLYL) BENZIMIDAZOLES.

Info

Publication number: CH546768A
Authority: CH; Switzerland
Prior art keywords: benzimidazoles; imidazolyl; nitro; preparation
Prior art date: 1969-04-19

Application number

CH1820172A

Other languages

German (de)

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1969-04-19

Filing date

1970-04-02

Publication date

1974-03-15

1970-04-02 Application filed by Schering Ag filed Critical Schering Ag

1974-03-15 Publication of CH546768A publication Critical patent/CH546768A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/95—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by nitrogen atoms, attached to other ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
- C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
- C07C209/325—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups reduction by other means than indicated in C07C209/34 or C07C209/36
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/30—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds
- C07C209/32—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups
- C07C209/36—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of nitrogen-to-oxygen or nitrogen-to-nitrogen bonds by reduction of nitro groups by reduction of nitro groups bound to carbon atoms of six-membered aromatic rings in presence of hydrogen-containing gases and a catalyst
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

CH1820172A 1969-04-19 1970-04-02 PROCESS FOR THE PREPARATION OF 2- (5-NITRO-2-IMIDAZOLYL) BENZIMIDAZOLES. CH546768A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE1920635A DE1920635C3 (en)	1969-04-19	1969-04-19	2- (1-methyl-5-nitro-2-imidazolyl) benzimidazoles

Publications (1)

Publication Number	Publication Date
CH546768A true CH546768A (en)	1974-03-15

Family

ID=5732064

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CH1820172A CH546768A (en)	1969-04-19	1970-04-02	PROCESS FOR THE PREPARATION OF 2- (5-NITRO-2-IMIDAZOLYL) BENZIMIDAZOLES.
CH491970A CH546774A (en)	1969-04-19	1970-04-02	PROCESS FOR THE PREPARATION OF 2- (5-NITRO-2-IMIDAZOLYL) BENZIMIDAZOLES.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CH491970A CH546774A (en)	1969-04-19	1970-04-02	PROCESS FOR THE PREPARATION OF 2- (5-NITRO-2-IMIDAZOLYL) BENZIMIDAZOLES.

Country Status (15)

Country	Link
JP (1)	JPS4914231B1 (en)
AT (1)	AT294075B (en)
BE (1)	BE749102A (en)
CH (2)	CH546768A (en)
CS (1)	CS167896B2 (en)
DE (1)	DE1920635C3 (en)
DK (1)	DK137758B (en)
ES (1)	ES378368A1 (en)
FI (1)	FI52861C (en)
FR (1)	FR2042351B1 (en)
GB (1)	GB1312056A (en)
NL (1)	NL7005703A (en)
NO (1)	NO126624B (en)
SE (1)	SE364962B (en)
ZA (1)	ZA702577B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4053472A (en) *	1969-04-19	1977-10-11	Schering Aktiengesellschaft	2-(5-nitro-2-imidazolyl)-benzimidazoles
IT1043840B (en) *	1971-05-08	1980-02-29	Poli Ind Chimica Spa	PYRIMIDINES 2 5 REPLACED AND PROCESS FOR THEIR PREPARATION
US3996238A (en) *	1972-02-08	1976-12-07	Ciba-Geigy Corporation	4- or 5-Nitroimidazoles and processes for their manufacture
BE795636A (en) *	1972-02-19	1973-08-20	Schering Ag	NITROIMIDAZOLYLPYRIMIDINES, AND THEIR PREPARATION PROCESS
PT78358B (en) *	1983-04-07	1986-05-30	Smith Kline French Lab	Chemical process
US5852011A (en) *	1994-05-31	1998-12-22	Mitsui Chemicals, Inc.	Benzimidazole derivatives
WO1996006831A1 (en) *	1994-08-26	1996-03-07	Auckland Division Cancer Society Of New Zealand Inc.	Novel dna-targeted alkylating agents

1969
- 1969-04-19 DE DE1920635A patent/DE1920635C3/en not_active Expired
1970
- 1970-03-27 CS CS2059A patent/CS167896B2/cs unknown
- 1970-04-02 CH CH1820172A patent/CH546768A/en not_active IP Right Cessation
- 1970-04-02 CH CH491970A patent/CH546774A/en not_active IP Right Cessation
- 1970-04-08 ES ES70378368A patent/ES378368A1/en not_active Expired
- 1970-04-15 DK DK188570AA patent/DK137758B/en unknown
- 1970-04-17 SE SE05326/70A patent/SE364962B/xx unknown
- 1970-04-17 AT AT351470A patent/AT294075B/en active
- 1970-04-17 NO NO01455/70A patent/NO126624B/no unknown
- 1970-04-17 BE BE749102D patent/BE749102A/en unknown
- 1970-04-17 FR FR707013970A patent/FR2042351B1/fr not_active Expired
- 1970-04-17 ZA ZA702577A patent/ZA702577B/en unknown
- 1970-04-17 FI FI701070A patent/FI52861C/en active
- 1970-04-20 NL NL7005703A patent/NL7005703A/xx not_active Application Discontinuation
- 1970-04-20 GB GB1874370A patent/GB1312056A/en not_active Expired
- 1970-04-20 JP JP45033734A patent/JPS4914231B1/ja active Pending

Also Published As

Publication number	Publication date
SE364962B (en)	1974-03-11
CS167896B2 (en)	1976-05-28
NO126624B (en)	1973-03-05
FR2042351A1 (en)	1971-02-12
CH546774A (en)	1974-03-15
BE749102A (en)	1970-10-19
DE1920635A1 (en)	1970-10-29
ES378368A1 (en)	1972-06-16
DK137758B (en)	1978-05-01
GB1312056A (en)	1973-04-04
DE1920635B2 (en)	1978-11-02
AT294075B (en)	1971-11-10
NL7005703A (en)	1970-10-21
FI52861B (en)	1977-08-31
DE1920635C3 (en)	1979-06-28
FR2042351B1 (en)	1973-07-13
DK137758C (en)	1978-10-09
JPS4914231B1 (en)	1974-04-05
ZA702577B (en)	1971-01-27
FI52861C (en)	1977-12-12

Publication	Publication Date	Title
AT299142B (en)	1972-06-12	Process for the preparation of 2,2-dimethylpropanediol- (1,3)
CH535239A (en)	1973-03-31	Process for the preparation of heterocyclically substituted N-benzylimidazoles
CH544116A (en)	1973-12-28	Process for the preparation of 2- (thienyl-3 -amino) -1,3-diazacycloalkenene (2)
CH556341A (en)	1974-11-29	PROCESS FOR THE PREPARATION OF 2-CYANOBENZIMIDAZOLES.
CH556335A (en)	1974-11-29	PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENOXYPYRROLIDINES.
CH552593A (en)	1974-08-15	PROCESS FOR THE PREPARATION OF PYRIDINTHIOACETAMIDE DERIVATIVES.
CH550176A (en)	1974-06-14	PROCESS FOR THE PREPARATION OF SUBSTITUTED N-AMINOALKYLARYLAMINO-IMIDAZOLINES- (2).
CH553181A (en)	1974-08-30	PROCESS FOR THE PREPARATION OF 4-HETERO-SUBSTITUTED AZETIDINONE- (2).
CH552633A (en)	1974-08-15	PROCESS FOR THE PREPARATION OF 2-HALOGENOETHYLPHOSPHONIC ACIDS.
CH535249A (en)	1973-03-31	Process for the preparation of 2-amino-4-hydroxy-6-hydroxymethyl-7,7-dimethyl-7,8-dihydropteridine
CH547284A (en)	1974-03-29	PROCESS FOR THE PREPARATION OF 1-HYDROXY-2-PYRIDONS.
CH531523A (en)	1972-12-15	Process for the preparation of 2,6-dichloro-4-heterocyclyl-pyridine-3,5-dicarbonitriles
CH546774A (en)	1974-03-15	PROCESS FOR THE PREPARATION OF 2- (5-NITRO-2-IMIDAZOLYL) BENZIMIDAZOLES.
CH552631A (en)	1974-08-15	PROCESS FOR THE PREPARATION OF N-ACYLDER DERIVATIVES OF PHOSPHORAMIDOTHIOATES.
CH558794A (en)	1975-02-14	PROCESS FOR THE PREPARATION OF 3-AROYLPYRROLIDINES.
CH508616A (en)	1971-06-15	Process for the preparation of 2-alkyl-3-hydroxy-4,5-dihydrofuran-4-ones
CH542854A (en)	1973-10-15	Process for the preparation of benzimidazole derivatives
CH529768A (en)	1972-10-31	Process for the preparation of benzimidazole derivatives
CH557365A (en)	1974-12-31	PROCESS FOR THE PREPARATION OF 5-AMINO-SUBSTITUTED IMIDAZOLES.
CH558802A (en)	1975-02-14	PROCESS FOR THE PREPARATION OF IMIDAZOLES.
CH525876A (en)	1972-07-31	Process for the preparation of 3-keto-6,7-methylene-20-spirox-4-enes
CH524556A (en)	1972-06-30	Process for the preparation of 2,3,6-trimethylhydroquinone
CH555857A (en)	1974-11-15	PROCESS FOR THE PREPARATION OF PYRRYLVINYLTHIAZOLIUM SALTS.
CH532569A (en)	1973-01-15	Process for the preparation of 6-alkoxy-5,6-dihydro-4H-pyrans
CH551410A (en)	1974-07-15	PROCESS FOR THE PREPARATION OF 2-PHENYLAMINO- (DELTA) 1-PYRROLINES.

Legal Events

Date	Code	Title	Description
1982-12-31	PL	Patent ceased