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CH484092A - Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren - Google Patents

Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren

Info

Publication number
CH484092A
CH484092A CH1076467A CH1076467A CH484092A CH 484092 A CH484092 A CH 484092A CH 1076467 A CH1076467 A CH 1076467A CH 1076467 A CH1076467 A CH 1076467A CH 484092 A CH484092 A CH 484092A
Authority
CH
Switzerland
Prior art keywords
preparation
carboxylic acids
heterocyclic carboxylic
new heterocyclic
new
Prior art date
Application number
CH1076467A
Other languages
English (en)
Inventor
Jonas Dr Zergenyi
Ernst Dr Habicht
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Priority to CH1807069A priority Critical patent/CH484095A/de
Priority to CH1806969A priority patent/CH484094A/de
Priority to CH1076467A priority patent/CH484092A/de
Priority to SE09914/68*A priority patent/SE364957B/xx
Priority to NO2865/68A priority patent/NO122751B/no
Priority to NO2864/68A priority patent/NO122656B/no
Priority to NL686810314A priority patent/NL139969B/xx
Priority to DK351368AA priority patent/DK121087B/da
Priority to DK351268AA priority patent/DK121514B/da
Priority to FI682064A priority patent/FI49416C/fi
Priority to FI682063A priority patent/FI49415C/fi
Priority to SE09915/68A priority patent/SE364270B/xx
Priority to NL686810315A priority patent/NL141185B/xx
Priority to US746267A priority patent/US3557152A/en
Priority to US746262A priority patent/US3580931A/en
Priority to YU1782/68A priority patent/YU32524B/xx
Priority to YU1783/68A priority patent/YU32705B/xx
Priority to ES356526A priority patent/ES356526A1/es
Priority to BG012203A priority patent/BG15387A3/bg
Priority to BE718654A priority patent/BE718654A/xx
Priority to CS719771*1A priority patent/CS153468B2/cs
Priority to BE718655D priority patent/BE718655A/xx
Priority to IE905/68A priority patent/IE32223B1/xx
Priority to BG012202A priority patent/BG15386A3/bg
Priority to SU1415775A priority patent/SU393827A3/ru
Priority to AT446869A priority patent/AT283346B/de
Priority to ES356525A priority patent/ES356525A1/es
Priority to IL30443A priority patent/IL30443A/xx
Priority to AT07301/68A priority patent/AT281811B/de
Priority to FR1585129D priority patent/FR1585129A/fr
Priority to GB1228615D priority patent/GB1228615A/en
Priority to BR200997/68A priority patent/BR6800997D0/pt
Priority to ES356524A priority patent/ES356524A1/es
Priority to PL1968128332A priority patent/PL69796B1/pl
Priority to AT729868A priority patent/AT280272B/de
Priority to GB35698/68A priority patent/GB1244761A/en
Priority to IL30442A priority patent/IL30442A/en
Priority to AT06940/69A priority patent/AT285595B/de
Priority to FR1603426D priority patent/FR1603426A/fr
Priority to DE19681793049 priority patent/DE1793049C3/de
Priority to CS547268A priority patent/CS153467B2/cs
Priority to DE19681793047 priority patent/DE1793047A1/de
Priority to IE904/68A priority patent/IE32222B1/xx
Priority to FR171418A priority patent/FR7989M/fr
Priority to FR171417A priority patent/FR7988M/fr
Publication of CH484092A publication Critical patent/CH484092A/de
Priority to YU1751/73A priority patent/YU33794B/xx
Priority to YU1749/73A priority patent/YU33956B/xx
Priority to YU1752/73A priority patent/YU33869B/xx
Priority to YU1750/73A priority patent/YU33861B/xx
Priority to YU1753/73A priority patent/YU33870B/xx
Priority to GT197640170A priority patent/GT197640170A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/008—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with tri- or tetrahalomethyl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Fertilizing (AREA)
CH1076467A 1967-07-28 1967-07-28 Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren CH484092A (de)

Priority Applications (51)

Application Number Priority Date Filing Date Title
CH1807069A CH484095A (de) 1967-07-28 1967-07-28 Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren
CH1806969A CH484094A (de) 1967-07-28 1967-07-28 Verfahren zur Herstellung von neuen Benzofuranderivaten und ihren Salzen
CH1076467A CH484092A (de) 1967-07-28 1967-07-28 Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren
SE09914/68*A SE364957B (de) 1967-07-28 1968-06-19
NO2865/68A NO122751B (de) 1967-07-28 1968-07-19
NO2864/68A NO122656B (de) 1967-07-28 1968-07-19
NL686810314A NL139969B (nl) 1967-07-28 1968-07-19 Werkwijze voor de bereiding van onverzadigde keto-carbonzuren met diuretische en saluretische werking, alsmede werkwijze voor de bereiding van farmaceutische preparaten die deze verbindingen bevatten en de daarbij verkregen gevormde farmaceutische preparaten.
DK351368AA DK121087B (da) 1967-07-28 1968-07-19 Analogifremgangsmåde til fremstilling af benzofurancarboxylsyrer eller salte deraf.
DK351268AA DK121514B (da) 1967-07-28 1968-07-19 Analogifremgangsmåde til fremstilling af heterocycliske carboxylsyrer eller salte deraf.
FI682064A FI49416C (fi) 1967-07-28 1968-07-19 Menetelmä uusien farmakologisesti aktiivisten bentsofuraani-2-karbonih appojohdannaisten valmistamiseksi.
FI682063A FI49415C (fi) 1967-07-28 1968-07-19 Menetelmä uusien farmakologisesti aktiivisten bentsofuraani-2-karbonih appojohdannaisten valmistamiseksi.
SE09915/68A SE364270B (de) 1967-07-28 1968-07-19
NL686810315A NL141185B (nl) 1967-07-28 1968-07-19 Werkwijze voor de bereiding van carbonzuren met diuretische en saluretische werking, en van geneesmiddelen, die deze verbindingen bevatten.
US746267A US3557152A (en) 1967-07-28 1968-07-22 5-(2-bromomethyl or chloromethyl-2-bromo or chloro alkanoyl) benzofuran-2-carboxylic acids
US746262A US3580931A (en) 1967-07-28 1968-07-22 5-(2-methylenealkanoyl)-benzofuran 7-carboxylic acids
YU1782/68A YU32524B (en) 1967-07-28 1968-07-25 Postopek za pripravo novih heterociklicnih karboksilnih kislin
YU1783/68A YU32705B (en) 1967-07-28 1968-07-25 Postopek za pripravo novih heterociklicnih karboksilnih kislin
ES356526A ES356526A1 (es) 1967-07-28 1968-07-26 Procedimiento para la preparacion de nuevos acidos carboxi-licos heterociclicos.
BG012203A BG15387A3 (bg) 1967-07-28 1968-07-26 Метод за получаване на нови хетероциклични карбонови киселини
BE718654A BE718654A (de) 1967-07-28 1968-07-26
CS719771*1A CS153468B2 (de) 1967-07-28 1968-07-26
BE718655D BE718655A (de) 1967-07-28 1968-07-26
IE905/68A IE32223B1 (en) 1967-07-28 1968-07-26 Novel carboxylic acids,processes for their production and compositions containing the same
BG012202A BG15386A3 (bg) 1967-07-28 1968-07-26 Метод за получаване на нови хетероциклични карбонови киселини
SU1415775A SU393827A3 (de) 1967-07-28 1968-07-26
AT446869A AT283346B (de) 1967-07-28 1968-07-26 Verfahren zur Herstellung von neuen Cumaron-, Benzo[b]thiopen- oder Indolderivaten und ihren Salzen
ES356525A ES356525A1 (es) 1967-07-28 1968-07-26 Procedimiento para la preparacion de nuevos acidos carboxi-licos heterociclicos.
IL30443A IL30443A (en) 1967-07-28 1968-07-26 Substituted benzofuran,benzothiophene and indole carboxylic acids and process for their production
AT07301/68A AT281811B (de) 1967-07-28 1968-07-26 Verfahren zur herstellung von neuen benzofuranderivaten und ihren salzen
FR1585129D FR1585129A (de) 1967-07-28 1968-07-26
GB1228615D GB1228615A (de) 1967-07-28 1968-07-26
BR200997/68A BR6800997D0 (pt) 1967-07-28 1968-07-26 Processo para a obtencao de nvos acidos cochosilicos heterocidicos
ES356524A ES356524A1 (es) 1967-07-28 1968-07-26 Procedimiento para la preparacion de nuevos acidos carboxi-licos heterociclicos.
PL1968128332A PL69796B1 (de) 1967-07-28 1968-07-26
AT729868A AT280272B (de) 1967-07-28 1968-07-26 Verfahren zur Herstellung von neuen Cumaron-, Benzo[b]thiophen- oder Indolderivaten und ihren Salzen
GB35698/68A GB1244761A (en) 1967-07-28 1968-07-26 Novel carboxylic acids, processes for their production and compositions containing same
IL30442A IL30442A (en) 1967-07-28 1968-07-26 Substituted benzofuran carboxylic acids and process for their production
AT06940/69A AT285595B (de) 1967-07-28 1968-07-26 Verfahren zur herstellung von neuen benzofuranderivaten und ihren salzen
FR1603426D FR1603426A (de) 1967-07-28 1968-07-26
DE19681793049 DE1793049C3 (de) 1967-07-28 1968-07-26 Benzofuran-2-carbonsaeuren und deren Salze mit pharmakologisch vertraeglichen anorganischen oder organischen Basen sowie Arzneimittel mit einem Gehalt dieser Verbindungen
CS547268A CS153467B2 (de) 1967-07-28 1968-07-26
DE19681793047 DE1793047A1 (de) 1967-07-28 1968-07-26 Verfahren zur Herstellung von neuen heterocyclischen Carbonsaeuren
IE904/68A IE32222B1 (en) 1967-07-28 1968-07-26 Novel heterocyclic carboxylic acids,process for their production and preparations containing same
FR171418A FR7989M (de) 1967-07-28 1968-10-25
FR171417A FR7988M (de) 1967-07-28 1968-10-25
YU1751/73A YU33794B (en) 1967-07-28 1973-06-28 Process for preparing novel heterocyclic carboxylic acids
YU1749/73A YU33956B (en) 1967-07-28 1973-06-28 Process for preparing novel heterocyclic carboxylic acids
YU1752/73A YU33869B (en) 1967-07-28 1973-06-28 Process for preparing novel heterocyclic carboxylic acids
YU1750/73A YU33861B (en) 1967-07-28 1973-06-28 Process for preparing novel heterocyclic carboxylic acids
YU1753/73A YU33870B (en) 1967-07-28 1973-07-28 Process for preparing novel heterocyclic carboxylic acids
GT197640170A GT197640170A (es) 1967-07-28 1976-02-13 Procedimiento para la preparacion de nuevos acidos carboxilicos heterociclicos.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1076467A CH484092A (de) 1967-07-28 1967-07-28 Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren
CH1363767 1967-09-29

Publications (1)

Publication Number Publication Date
CH484092A true CH484092A (de) 1970-01-15

Family

ID=25707248

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1076467A CH484092A (de) 1967-07-28 1967-07-28 Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren

Country Status (14)

Country Link
US (2) US3557152A (de)
BE (2) BE718655A (de)
CH (1) CH484092A (de)
DE (2) DE1793047A1 (de)
DK (1) DK121514B (de)
ES (3) ES356525A1 (de)
FR (4) FR1585129A (de)
GB (2) GB1244761A (de)
IE (1) IE32223B1 (de)
IL (1) IL30443A (de)
NL (2) NL141185B (de)
NO (1) NO122656B (de)
SE (1) SE364957B (de)
YU (6) YU32524B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3627785A (en) * 1968-07-22 1971-12-14 Geigy Chem Corp Benzofuran-2-carboxylic acids
BE758838A (fr) * 1969-11-13 1971-05-12 Geigy Ag J R Esters d'acides carboxyliques heterocyliques et medicaments renfermant de telles substances
BE758956R (fr) * 1969-11-13 1971-05-13 Geigy Ag J R Acides heterocycliques et medicaments contenant de tels
BE758955R (fr) * 1969-11-13 1971-05-13 Geigy Ag J R Acides carboxyliques heterocycliques et medicaments contenant de tels
BE759137R (fr) * 1969-11-20 1971-05-19 Geigy Ag J R Acides carboxyliques heterocycliques et medicaments contenant de tels
US4933351A (en) * 1983-10-31 1990-06-12 Merck Frosst Canada, Inc. Benzofuran 2-carbox amides useful as inhibitors of leukoriene biosynthesis
US4822803A (en) * 1983-10-31 1989-04-18 Merck Frosst Canada, Inc. Benzofuran 2-carboxylic acid hydrazides useful as inhibitors of leukotriene biosynthesis
US4663347A (en) * 1983-10-31 1987-05-05 Merck Frosst Canada, Inc. Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis
US4654365A (en) * 1985-09-26 1987-03-31 Merck & Co., Inc. 2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxylic acids, and their salts useful in the treatment of brain injury

Also Published As

Publication number Publication date
DE1793049B2 (de) 1972-12-21
NO122656B (de) 1971-07-26
YU175373A (en) 1977-12-31
DE1793049A1 (de) 1972-04-20
FR7989M (de) 1970-06-08
DK121514B (da) 1971-10-25
NL6810314A (de) 1969-01-30
IE32223B1 (en) 1973-05-16
YU175273A (en) 1977-12-31
YU33956B (en) 1978-09-08
YU33861B (en) 1978-06-30
YU33869B (en) 1978-06-30
US3557152A (en) 1971-01-19
DE1793049C3 (de) 1973-07-19
IE32223L (en) 1969-01-28
GB1244761A (en) 1971-09-02
IL30443A (en) 1971-11-29
BE718654A (de) 1969-01-27
BE718655A (de) 1969-01-27
YU178268A (en) 1974-06-30
ES356525A1 (es) 1970-06-01
ES356526A1 (es) 1970-04-01
IL30443A0 (en) 1968-09-26
DE1793047A1 (de) 1972-04-20
YU175073A (en) 1977-12-31
GB1228615A (de) 1971-04-15
YU175173A (en) 1977-10-31
FR7988M (de) 1970-06-08
NL139969B (nl) 1973-10-15
ES356524A1 (es) 1970-01-16
NL6810315A (de) 1969-01-30
YU33870B (en) 1978-06-30
US3580931A (en) 1971-05-25
YU174967A (en) 1978-02-28
SE364957B (de) 1974-03-11
FR1603426A (de) 1971-04-19
FR1585129A (de) 1970-01-09
NL141185B (nl) 1974-02-15
YU33794B (en) 1978-05-15
YU32524B (en) 1974-12-31

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